Ectopic pregnancy(EP)could be defined as any embryo that got implanted in any site rather than the endometrial cavity.Lately,different types of EP were reportedly managed by high-intensity focused ultrasound(HIFU).We ...Ectopic pregnancy(EP)could be defined as any embryo that got implanted in any site rather than the endometrial cavity.Lately,different types of EP were reportedly managed by high-intensity focused ultrasound(HIFU).We aimed to pool all available data in a systematic review without meta-analysis and investigate the efficacy and safety tendencies of HIFU among different types of EP.We applied our comprehensive terms in Google Scholar,PubMed,Scopus,Ovid,and PubMed Central databases from their inception until September 23.Retrieved references were gathered using EndNote in which we omitted the duplicates and exported the record for screening.Data regarding character-istics,safety and efficacy outcomes,and baseline information of the enrolled population were extracted.The eligible case reports were assessed using a tool by Murad and colleagues,while the quality of the included cohorts was appraised using the NIH tool.We retrieved 6637 studies,which were scruti-nized by titles and abstracts.We scrutinized the full texts of 36 studies and ultimately included a total of 17 studies.All studies were conducted in China,and on different types of ectopic pregnancy including tubal,cervical,intra-mural,caesarian scar,and corneal ectopic pregnancy.The mean age of enrolled patients was 33.03 years,and we pooled a total sample of 853 patients.The follow-up period varied widely among the included studies,ranging from 1.3 months to up to 69 months.Normal menstruation recurred after a mean of 35 days,as reported by nine studies.Most of the included studies reported normalβ-HCG after around 30-40 days.Twelve studies with 757 patients reported a cumulative incidence of 179 cases of abdominal pain after HIFU.Neither of the enrolled patients reportedly complained of skin burn after HIFU.We suggested managing EP patients with HIFU,especially when seeking further conceiving.High-quality randomized controlled trials are required to draw a stronger level of evidence.展开更多
Purpose: The aim of this study was to examine if package inserts (PIs) supplied with prescribed medications in the Emirate of Abu Dhabi contain all relevant information to the safe and appropriate use of these medicat...Purpose: The aim of this study was to examine if package inserts (PIs) supplied with prescribed medications in the Emirate of Abu Dhabi contain all relevant information to the safe and appropriate use of these medications. Methods: Sixty seven PIs for prescription—only medications were evaluated against a set of safety criteria published from the Ministry of Health. Results: Analyzed PIs showed many deficiencies with regard to the Ministry of Health (MOH) Investigation New Drug Application (INDA) requirements. Particularly of concern were side effects, warnings, use in pregnancy, lactation, and the storage conditions for the product. Conclusions: This study indicated that information relevant to the safe and appropriate use of medications was not uniformly mentioned in the PIs analyzed. To avoid medication errors due to deficits in the current PIs, we recommend regulatory oversight and regulator audits from pharmaceutical company, followed by enhancement of regulations requiring companies to also create patient information leaflets.展开更多
The interest of this research: there is oil seepage at the contact between coal seam-A and sandstone facies of Warukin Formation, so it is necessary to study where is the source rock. The correlation between HI and Tm...The interest of this research: there is oil seepage at the contact between coal seam-A and sandstone facies of Warukin Formation, so it is necessary to study where is the source rock. The correlation between HI and Tmax as result from rock eval pyrolysis shows that the shale of the Warukin Formation is immature while the correlation between HI and OI shows oil prone. The vitrinite (Ro) reflectance of Central Wara coal is between 0.48% up to 0.5% (immature), the content of the vitrinite group is 68.0 - 84.8 (% Vol.), Liptinite 3.0 - 14.0 (% Vol.) and inertinite 0.48 - 25.0 (% Vol.). The high content of liptinite mineral groups (14% Vol.) and the presence of exsudatinite maceral are as an initial indication of bitumenization of oil formation when there is a change in reflectance and fluorescence. Therefore, Central Wara coal plays an important role as the source rock of the Warukin Formation, although the maturity level is immature, the presence of exsudatinite maceral is believed to be the source of origin for producing oil, where the organic material comes from terrestrial.展开更多
The jet pump is an artificial lift employed when the reservoir pressure declines and the well deviation increases.The use of computer well models for optimizing the oil well output has proven to be a suc-cessful strat...The jet pump is an artificial lift employed when the reservoir pressure declines and the well deviation increases.The use of computer well models for optimizing the oil well output has proven to be a suc-cessful strategy,and has helped increasing the efficiency and production of numerous wells.The objective of this study was to use a production optimization technique that achieves some improve-ments,and recommend approaches toward increasing the oil well production.The effects of the motive fluid flow rate and pressure on the oil production rate were investigated to determine the optimal in-jection rate and pressure on the performance of the deep well water-oil axial jet-pump.Additionally,the effects of the well-head pressure,water cut,and roughness of tubing on oil production of this jet pump type were investigated.The results revealed that the impact on the oil lift performance is significant.The oil production increased by 19.43%,and the optimal economic value for the injection rate and pressure for the GA-1A well are 744.44 BFPD and 2722.22 psig,respectively.In summary,increasing the tubing roughness decreased the well's total liquid production.Thus,maintaining the well integrity is a very important factor because not doing so can lower the productivity by up to 20%-25%.展开更多
文摘Ectopic pregnancy(EP)could be defined as any embryo that got implanted in any site rather than the endometrial cavity.Lately,different types of EP were reportedly managed by high-intensity focused ultrasound(HIFU).We aimed to pool all available data in a systematic review without meta-analysis and investigate the efficacy and safety tendencies of HIFU among different types of EP.We applied our comprehensive terms in Google Scholar,PubMed,Scopus,Ovid,and PubMed Central databases from their inception until September 23.Retrieved references were gathered using EndNote in which we omitted the duplicates and exported the record for screening.Data regarding character-istics,safety and efficacy outcomes,and baseline information of the enrolled population were extracted.The eligible case reports were assessed using a tool by Murad and colleagues,while the quality of the included cohorts was appraised using the NIH tool.We retrieved 6637 studies,which were scruti-nized by titles and abstracts.We scrutinized the full texts of 36 studies and ultimately included a total of 17 studies.All studies were conducted in China,and on different types of ectopic pregnancy including tubal,cervical,intra-mural,caesarian scar,and corneal ectopic pregnancy.The mean age of enrolled patients was 33.03 years,and we pooled a total sample of 853 patients.The follow-up period varied widely among the included studies,ranging from 1.3 months to up to 69 months.Normal menstruation recurred after a mean of 35 days,as reported by nine studies.Most of the included studies reported normalβ-HCG after around 30-40 days.Twelve studies with 757 patients reported a cumulative incidence of 179 cases of abdominal pain after HIFU.Neither of the enrolled patients reportedly complained of skin burn after HIFU.We suggested managing EP patients with HIFU,especially when seeking further conceiving.High-quality randomized controlled trials are required to draw a stronger level of evidence.
文摘Purpose: The aim of this study was to examine if package inserts (PIs) supplied with prescribed medications in the Emirate of Abu Dhabi contain all relevant information to the safe and appropriate use of these medications. Methods: Sixty seven PIs for prescription—only medications were evaluated against a set of safety criteria published from the Ministry of Health. Results: Analyzed PIs showed many deficiencies with regard to the Ministry of Health (MOH) Investigation New Drug Application (INDA) requirements. Particularly of concern were side effects, warnings, use in pregnancy, lactation, and the storage conditions for the product. Conclusions: This study indicated that information relevant to the safe and appropriate use of medications was not uniformly mentioned in the PIs analyzed. To avoid medication errors due to deficits in the current PIs, we recommend regulatory oversight and regulator audits from pharmaceutical company, followed by enhancement of regulations requiring companies to also create patient information leaflets.
文摘The interest of this research: there is oil seepage at the contact between coal seam-A and sandstone facies of Warukin Formation, so it is necessary to study where is the source rock. The correlation between HI and Tmax as result from rock eval pyrolysis shows that the shale of the Warukin Formation is immature while the correlation between HI and OI shows oil prone. The vitrinite (Ro) reflectance of Central Wara coal is between 0.48% up to 0.5% (immature), the content of the vitrinite group is 68.0 - 84.8 (% Vol.), Liptinite 3.0 - 14.0 (% Vol.) and inertinite 0.48 - 25.0 (% Vol.). The high content of liptinite mineral groups (14% Vol.) and the presence of exsudatinite maceral are as an initial indication of bitumenization of oil formation when there is a change in reflectance and fluorescence. Therefore, Central Wara coal plays an important role as the source rock of the Warukin Formation, although the maturity level is immature, the presence of exsudatinite maceral is believed to be the source of origin for producing oil, where the organic material comes from terrestrial.
文摘The jet pump is an artificial lift employed when the reservoir pressure declines and the well deviation increases.The use of computer well models for optimizing the oil well output has proven to be a suc-cessful strategy,and has helped increasing the efficiency and production of numerous wells.The objective of this study was to use a production optimization technique that achieves some improve-ments,and recommend approaches toward increasing the oil well production.The effects of the motive fluid flow rate and pressure on the oil production rate were investigated to determine the optimal in-jection rate and pressure on the performance of the deep well water-oil axial jet-pump.Additionally,the effects of the well-head pressure,water cut,and roughness of tubing on oil production of this jet pump type were investigated.The results revealed that the impact on the oil lift performance is significant.The oil production increased by 19.43%,and the optimal economic value for the injection rate and pressure for the GA-1A well are 744.44 BFPD and 2722.22 psig,respectively.In summary,increasing the tubing roughness decreased the well's total liquid production.Thus,maintaining the well integrity is a very important factor because not doing so can lower the productivity by up to 20%-25%.