For decades,Xu has been committed to fulfilling the duty and mission of a scientist and educator—diving into the laws of nature,caring deeply for the nation,and earnestly cultivating younger generations.
From cracking the code of viruses to mentoring the next generation of scientists,the former president of Nankai University has contributed a lot to turning microscopic discoveries into monumental shields for global he...From cracking the code of viruses to mentoring the next generation of scientists,the former president of Nankai University has contributed a lot to turning microscopic discoveries into monumental shields for global health.OVER the past 40 years,one man has distinguished himself through a deep commitment to researching protein structures of high pathogenic viruses,and published numerous significant works in top international scientific journals.展开更多
This study explores a novel method for processing cotton stalks—an abundant agricultural byproduct—into long strips that serve as sustainable raw material for engineered bio-based panels.To evaluate the effect of ra...This study explores a novel method for processing cotton stalks—an abundant agricultural byproduct—into long strips that serve as sustainable raw material for engineered bio-based panels.To evaluate the effect of raw material morphology on panel’s performance,two types of cotton stalk-based panels were developed:one using long strips,maintaining fiber continuity,and the other using ground particles,representing conventional processing.A wood strand-based panel made from commercial southern yellow pine strands served as the control.All panels were bonded using phenol-formaldehyde resin and hot-pressed to a target thickness of 12.7 mm and density of 640 kg/m^(3).Their mechanical and physical properties were evaluated through internal bond,bending,thickness swelling,and water absorption tests.Both cotton stalk-based panels showed improved bonding performance compared to the control.The internal bond of the strip-based panel was nearly four times higher than that of the control,while the particlebased panel exceeded it by a factor of two.The strip-based panel showed approximately 15% lower bending stiffness than the wood strand-based panel,yet it surpassed it in load-carrying capacity by 5%.In contrast,the particleboard showed significantly lower bending performance than the strip-based and control panels,despite particle processing being a more conventional method.Both cotton stalk-based panels exhibited higher water absorption and thickness swelling than the wood strand panel.Overall,cotton stalk-based panels—particularly those using strip processing—show promisingmechanical properties,suggesting potential applications in sheathing,furniture,and interior paneling.However,improvements in dimensional stability are needed for broader use.展开更多
The diagnostic efficacy of contemporary bioimaging technologies remains constrained by inherent limitations of conventional imaging agents,including suboptimal sensitivity,off-target biodistribution,and inherent cytot...The diagnostic efficacy of contemporary bioimaging technologies remains constrained by inherent limitations of conventional imaging agents,including suboptimal sensitivity,off-target biodistribution,and inherent cytotoxicity.These limitations have catalyzed the development of intelligent stimuli-responsive block copolymers-based bioimaging agents,which was engineered to dynamically respond to endogenous biochemical cues(e.g.,p H gradients,redox potential,enzyme activity,hypoxia environment) or exogenous physical triggers(e.g.,photoirradiation,thermal gradients,ultrasound(US)/magnetic stimuli).Through spatiotemporally controlled structural transformations,stimuli-responsive block copolymers enable precise contrast targeting,activatable signal amplification,and theranostic integration,thereby substantially enhancing signal-to-noise ratios of bioimaging and diagnostic specificity.Hence,this mini-review systematically examines molecular engineering principles for designing p H-,redox-,enzyme-,light-,thermo-,and US/magnetic-responsive polymers,with emphasis on structure-property relationships governing imaging performance modulation.Furthermore,we critically analyze emerging strategies for optical imaging,US synergies,and magnetic resonance imaging(MRI).Multimodal bioimaging has also been elaborated,which could overcome the inherent trade-offs between resolution,penetration depth,and functional specificity in single-modal approaches.By elucidating mechanistic insights and translational challenges,this mini-review aims to establish a design framework of stimuli-responsive block copolymersbased for high fidelity bioimaging agents and accelerate their clinical translation in precise diagnosis and therapy.展开更多
Developing advanced polymeric materials with enhanced mechanical properties and functionalities has been a long-standing goal in materials science.Recently,supramolecular polymeric materials (SPMs) have drawn increase...Developing advanced polymeric materials with enhanced mechanical properties and functionalities has been a long-standing goal in materials science.Recently,supramolecular polymeric materials (SPMs) have drawn increased attention due to their unique properties and potential applications in self-healing,shape memory,sensors,and flexible electronics.Here,we develop an ionic cluster-optimized microphase separation strategy to enhance the toughening and energy dissipation capabilities of polydisulfide-based supramolecular polymers.The mechanical properties,including Young’s modulus and toughness,are significantly improved by integrating the quadruple H-bonding 2-ureido-4-pyrimidone (UPy) induced microphase separation with iron(Ⅲ)-to-carboxylate ionic clusters.By combining established chemical approaches with adjustable polymer phase ratios,it is revealed that the synergistic effect of these factors expands the interchain spacing,facilitates the formation of microphase domains,and enhances the tolerance of polythioctic acid-based polymers to external mechanical and thermal stimuli,meeting the practical requirements for industrial plastic applications.Moreover,the UPy-functionalized polymers incorporating iron carboxylate clusters exhibit good one-way shape memory behavior with practical applicability at a relatively low recovery temperature.Our work demonstrates a novel strategy for constructing industrially viable shape memory dynamic SPMs and paves the way for future innovations in developing SPMs.展开更多
As a key low-carbon energy source,nuclear power plays a vital role in the global transition toward sustainable energy.Photocatalytic uranium extraction from seawater(UES)offers a promising solution to ensure long-term...As a key low-carbon energy source,nuclear power plays a vital role in the global transition toward sustainable energy.Photocatalytic uranium extraction from seawater(UES)offers a promising solution to ensure long-term uranium supply but is challenged by ultra-low uranium concentrations and ion interference.To overcome these issues,we design three diketopyrrolopyrrole-based covalent organic frameworks(COFs)via a synergisticπ-extended lock and carboxyl-functionalized anchor molecular engineering strategy.Among them,TPy-DPP-COF features a covalently lockedπ-conjugated structure that enhances planarity,optimizes energy alignment,and minimizes exciton binding energy,thereby promoting charge transfer and suppressing recombination.Concurrently,carboxyl groups enable uranyl-specific coordination and create local electric fields to facilitate charge separation.These features contribute to the outstanding performance of TPy-DPP-COF,which achieves a high uranium adsorption capacity of 16.33 mg g−1 in natural seawater under irradiation,with only 29.3%capacity loss after 10 cycles,surpassing industrial benchmarks.Density functional theory(DFT)calculations and experimental studies reveal a synergistic photocatalysis-adsorption pathway,with DPP units acting as active sites for uranium reduction.This work highlights a molecular design strategy for developing efficient COF-based photocatalysts for practical marine uranium recovery.展开更多
Objectives:Colorectal cancer(CRC)is a major global health burden,and Urolithin A(Uro-A)has emerged as a promising anticancer agent.This systematic review aims to synthesize current in vitro evidence on the anticancer ...Objectives:Colorectal cancer(CRC)is a major global health burden,and Urolithin A(Uro-A)has emerged as a promising anticancer agent.This systematic review aims to synthesize current in vitro evidence on the anticancer effects of Uro-A in CRC,highlighting effective concentration ranges,exposure times,relevant outcomes,and underlying molecular mechanisms.Methods:Following PRISMA 2020 guidelines,a systematic search was conducted in PubMed,Scopus,and Web of Science using the following strategy:(colorectal cancer)AND(urolithin a)OR(3,8-dihydroxy-6H-dibenzo(b,d)pyran-6-one).Eligibility criteria were defined by the PICO framework:(P)in vitro CRC cell models;(I)Uro-A alone or combined treatments;(C)No intervention,vehicle or other treatments;(O)Relevant anticancer outcomes of Uro-A in CRC.Only original,full-text,in vitro studies in English were included.Risk of bias was assessed using ToxRTool.A qualitative synthesis was performed due to the heterogeneity of the included studies.Results:Fifteen studies met inclusion criteria,involving CRC cell lines(Caco-2,HCT-116,HT-29,SW480,SW620)and normal colon fibroblasts(CCD18-Co).Uro-A inhibited CRC cell proliferation,clonogenic growth,cancer stem cells properties,migration,and invasion,and induced cell cycle arrest,apoptosis,autophagy,and senescence,through modulation of key signaling pathways and proteins.Co-treatments with conventional chemotherapeutics and microbiota-derived metabolites showed additive or synergistic effects.Discussion:The findings support UroA’s potential as a preventive or adjuvant agent in CRC treatment.However,preclinical nature of the evidence and methodological heterogeneity hinder clinical extrapolation to in vivo contexts.Human clinical trials are necessary to overcome these limitations.Other:This review was registered in PROSPERO(CRD420251070874)and supported by FCT/MCTES UIDP/05608/2020 and UIDB/05608/2020.Institutional.展开更多
Hard carbon(HC)is a promising anode candidate for sodium-ion batteries(SIBs),yet its application is plagued by unstable interfaces and poor long-term cyclability.Herein,we develop a facile solvent evaporation strategy...Hard carbon(HC)is a promising anode candidate for sodium-ion batteries(SIBs),yet its application is plagued by unstable interfaces and poor long-term cyclability.Herein,we develop a facile solvent evaporation strategy to synthesize ultrathin Al_(2)O_(3)-coated biomass-derived HC(GSC-Al_(2)O_(3)-3%).The conformal Al_(2)O_(3)layer passivates defects and micropores,suppresses side reactions,and promotes the formation of a robust organic-inorganic hybrid solid electrolyte interphase.Comprehensive characterizations,including in situ X-ray diffraction,ex situ Raman spectra,X-ray photoelectron spectroscopy,time of flight secondary ion mass spectrometry,solid-state 27Al nuclear magnetic resonance,and atomic force microscope modulus mapping,demonstrate that Al_(2)O_(3)actively participates in SEI reconstruction,enhancing the chemical and mechanical stability.Electrochemical tests reveal that the optimized GSC-Al_(2)O_(3)-3%anode delivers 91%capacity retention after 1000 cycles at 1.0 A g^(-1),and possesses excellent wide-temperature tolerance(149.3 mAh g^(-1)at-30℃and 286.8 mAh g^(-1)at 60℃).Mechanistic studies confirm a synergistic Na+storage process involving"adsorption-intercalation-pore filling,"while density functional theory calculations and electrostatic potential mapping reveal that Al_(2)O_(3)coating regulates interfacial charge distribution and reduces Na+migration barriers.A full cell paired with a NaNi_(0.5)Fe_(0.5)MnO_(4)cathode exhibits a high initial capacity of 395.7 mAh g^(-1)and outstanding cycling stability(200 cycles).This work provides fundamental mechanistic insights into interfacial engineering of HC and establishes a cost-effective,scalable route for the next generation highperformance SIBs.展开更多
Retinal ganglion cells are susceptible to neurodegenerative conditions and their death drives common forms of irreversible vision loss.In mice,there are 46 transcriptionally unique retinal ganglion cell types that dem...Retinal ganglion cells are susceptible to neurodegenerative conditions and their death drives common forms of irreversible vision loss.In mice,there are 46 transcriptionally unique retinal ganglion cell types that demonstrate different susceptibilities to degeneration.Recent transcriptional experiments defined a novel retinal ganglion cell type that survives particularly well and uniquely expresses high levels of the orphan G-protein-coupled receptor 88.Motivated to study this retinal ganglion cell type,we obtained GPR88-Cre transgenic mice to identify the novel well-surviving retinal ganglion cells and examine their survival and regenerative potential.Our experiments demonstrate that this unidentified retinal ganglion cell type is likely accordant with previously described ON-direction-selective retinal ganglion cells.Interestingly,we find that ON-direction-selective retinal ganglion cells are resilient,but demonstrate limited potential to regenerate their axons in response to well-characterized regenerative treatments.Studying the molecular properties of the ON-direction-selective retinal ganglion cells could unlock new therapeutics to preserve retinal ganglion cells in patients.展开更多
The renowned scientist is academician of the Chinese Academy of Sciences,former president of Tsinghua University,and chair of the Tengchong Scientists Forum.ACADEMICIAN of the Chinese Academy of Sciences,former presid...The renowned scientist is academician of the Chinese Academy of Sciences,former president of Tsinghua University,and chair of the Tengchong Scientists Forum.ACADEMICIAN of the Chinese Academy of Sciences,former president of Tsinghua University,and chair of the Tengchong Scientists Forum,Gu Binglin is one of the world’s top physicists and materials scientist,and a pioneer in the field of materials design.展开更多
文摘For decades,Xu has been committed to fulfilling the duty and mission of a scientist and educator—diving into the laws of nature,caring deeply for the nation,and earnestly cultivating younger generations.
文摘From cracking the code of viruses to mentoring the next generation of scientists,the former president of Nankai University has contributed a lot to turning microscopic discoveries into monumental shields for global health.OVER the past 40 years,one man has distinguished himself through a deep commitment to researching protein structures of high pathogenic viruses,and published numerous significant works in top international scientific journals.
基金supported by the intramural research program of the U.S.Department of Agriculture,National Institute of Food and Agriculture,Biobased Economy Through Biobased Products,under Award#2023-68016-40132.
文摘This study explores a novel method for processing cotton stalks—an abundant agricultural byproduct—into long strips that serve as sustainable raw material for engineered bio-based panels.To evaluate the effect of raw material morphology on panel’s performance,two types of cotton stalk-based panels were developed:one using long strips,maintaining fiber continuity,and the other using ground particles,representing conventional processing.A wood strand-based panel made from commercial southern yellow pine strands served as the control.All panels were bonded using phenol-formaldehyde resin and hot-pressed to a target thickness of 12.7 mm and density of 640 kg/m^(3).Their mechanical and physical properties were evaluated through internal bond,bending,thickness swelling,and water absorption tests.Both cotton stalk-based panels showed improved bonding performance compared to the control.The internal bond of the strip-based panel was nearly four times higher than that of the control,while the particlebased panel exceeded it by a factor of two.The strip-based panel showed approximately 15% lower bending stiffness than the wood strand-based panel,yet it surpassed it in load-carrying capacity by 5%.In contrast,the particleboard showed significantly lower bending performance than the strip-based and control panels,despite particle processing being a more conventional method.Both cotton stalk-based panels exhibited higher water absorption and thickness swelling than the wood strand panel.Overall,cotton stalk-based panels—particularly those using strip processing—show promisingmechanical properties,suggesting potential applications in sheathing,furniture,and interior paneling.However,improvements in dimensional stability are needed for broader use.
基金supported by the National Natural Science Foundation of China (Nos.22208218,22078196,and 22278268)the Natural Science Foundation of Shanghai (No.22ZR1460400)Collaborative Innovation Center of Fragrance Flavour and Cosmetics,and Collaborative Innovation Project of Shanghai Institute of Technology (No.XTCX2023-07)。
文摘The diagnostic efficacy of contemporary bioimaging technologies remains constrained by inherent limitations of conventional imaging agents,including suboptimal sensitivity,off-target biodistribution,and inherent cytotoxicity.These limitations have catalyzed the development of intelligent stimuli-responsive block copolymers-based bioimaging agents,which was engineered to dynamically respond to endogenous biochemical cues(e.g.,p H gradients,redox potential,enzyme activity,hypoxia environment) or exogenous physical triggers(e.g.,photoirradiation,thermal gradients,ultrasound(US)/magnetic stimuli).Through spatiotemporally controlled structural transformations,stimuli-responsive block copolymers enable precise contrast targeting,activatable signal amplification,and theranostic integration,thereby substantially enhancing signal-to-noise ratios of bioimaging and diagnostic specificity.Hence,this mini-review systematically examines molecular engineering principles for designing p H-,redox-,enzyme-,light-,thermo-,and US/magnetic-responsive polymers,with emphasis on structure-property relationships governing imaging performance modulation.Furthermore,we critically analyze emerging strategies for optical imaging,US synergies,and magnetic resonance imaging(MRI).Multimodal bioimaging has also been elaborated,which could overcome the inherent trade-offs between resolution,penetration depth,and functional specificity in single-modal approaches.By elucidating mechanistic insights and translational challenges,this mini-review aims to establish a design framework of stimuli-responsive block copolymersbased for high fidelity bioimaging agents and accelerate their clinical translation in precise diagnosis and therapy.
基金supported by the National Natural Science Foundation of China(No.22375063)Science and Technology Commission of Shanghai Municipality(No.23JC1401700)the Fundamental Research Funds for the Central Universities.
文摘Developing advanced polymeric materials with enhanced mechanical properties and functionalities has been a long-standing goal in materials science.Recently,supramolecular polymeric materials (SPMs) have drawn increased attention due to their unique properties and potential applications in self-healing,shape memory,sensors,and flexible electronics.Here,we develop an ionic cluster-optimized microphase separation strategy to enhance the toughening and energy dissipation capabilities of polydisulfide-based supramolecular polymers.The mechanical properties,including Young’s modulus and toughness,are significantly improved by integrating the quadruple H-bonding 2-ureido-4-pyrimidone (UPy) induced microphase separation with iron(Ⅲ)-to-carboxylate ionic clusters.By combining established chemical approaches with adjustable polymer phase ratios,it is revealed that the synergistic effect of these factors expands the interchain spacing,facilitates the formation of microphase domains,and enhances the tolerance of polythioctic acid-based polymers to external mechanical and thermal stimuli,meeting the practical requirements for industrial plastic applications.Moreover,the UPy-functionalized polymers incorporating iron carboxylate clusters exhibit good one-way shape memory behavior with practical applicability at a relatively low recovery temperature.Our work demonstrates a novel strategy for constructing industrially viable shape memory dynamic SPMs and paves the way for future innovations in developing SPMs.
基金the Young Elite Scientists Sponsorship Program by JXAST(2024QT11)the National Natural Science Foundation of China(22465001,22309003)the Jiangxi Provincial Natural Science Foundation(20232BAB203042,20242BAB22002).
文摘As a key low-carbon energy source,nuclear power plays a vital role in the global transition toward sustainable energy.Photocatalytic uranium extraction from seawater(UES)offers a promising solution to ensure long-term uranium supply but is challenged by ultra-low uranium concentrations and ion interference.To overcome these issues,we design three diketopyrrolopyrrole-based covalent organic frameworks(COFs)via a synergisticπ-extended lock and carboxyl-functionalized anchor molecular engineering strategy.Among them,TPy-DPP-COF features a covalently lockedπ-conjugated structure that enhances planarity,optimizes energy alignment,and minimizes exciton binding energy,thereby promoting charge transfer and suppressing recombination.Concurrently,carboxyl groups enable uranyl-specific coordination and create local electric fields to facilitate charge separation.These features contribute to the outstanding performance of TPy-DPP-COF,which achieves a high uranium adsorption capacity of 16.33 mg g−1 in natural seawater under irradiation,with only 29.3%capacity loss after 10 cycles,surpassing industrial benchmarks.Density functional theory(DFT)calculations and experimental studies reveal a synergistic photocatalysis-adsorption pathway,with DPP units acting as active sites for uranium reduction.This work highlights a molecular design strategy for developing efficient COF-based photocatalysts for practical marine uranium recovery.
基金supported by FCT/MCTES UIDP/05608/2020(https://doi.org/10.54499/UIDP/05608/2020,accessed on 01 July 2025)UIDB/05608/2020(https://doi.org/10.54499/UIDB/05608/2020,accessed on 01 July 2025).Institutional.
文摘Objectives:Colorectal cancer(CRC)is a major global health burden,and Urolithin A(Uro-A)has emerged as a promising anticancer agent.This systematic review aims to synthesize current in vitro evidence on the anticancer effects of Uro-A in CRC,highlighting effective concentration ranges,exposure times,relevant outcomes,and underlying molecular mechanisms.Methods:Following PRISMA 2020 guidelines,a systematic search was conducted in PubMed,Scopus,and Web of Science using the following strategy:(colorectal cancer)AND(urolithin a)OR(3,8-dihydroxy-6H-dibenzo(b,d)pyran-6-one).Eligibility criteria were defined by the PICO framework:(P)in vitro CRC cell models;(I)Uro-A alone or combined treatments;(C)No intervention,vehicle or other treatments;(O)Relevant anticancer outcomes of Uro-A in CRC.Only original,full-text,in vitro studies in English were included.Risk of bias was assessed using ToxRTool.A qualitative synthesis was performed due to the heterogeneity of the included studies.Results:Fifteen studies met inclusion criteria,involving CRC cell lines(Caco-2,HCT-116,HT-29,SW480,SW620)and normal colon fibroblasts(CCD18-Co).Uro-A inhibited CRC cell proliferation,clonogenic growth,cancer stem cells properties,migration,and invasion,and induced cell cycle arrest,apoptosis,autophagy,and senescence,through modulation of key signaling pathways and proteins.Co-treatments with conventional chemotherapeutics and microbiota-derived metabolites showed additive or synergistic effects.Discussion:The findings support UroA’s potential as a preventive or adjuvant agent in CRC treatment.However,preclinical nature of the evidence and methodological heterogeneity hinder clinical extrapolation to in vivo contexts.Human clinical trials are necessary to overcome these limitations.Other:This review was registered in PROSPERO(CRD420251070874)and supported by FCT/MCTES UIDP/05608/2020 and UIDB/05608/2020.Institutional.
基金supported by National Natural Science Foundation,China(Nos.52261135632,U21A20284)Natural Science Foundation of Henan,China(No.232300421080)+3 种基金Program for Innovative Team(in Science and Technology)in University of Henan Province,China(No.24IRTSTHN006)Henan Distinguished Foreign Scientists Workgroup in Electrochemical Energy Storage,China(No.GZS2015013)Key Scientific Research Programs in Universities of Henan Province,China-Special Projects for Basic Research(No.23ZX008)Cultivation Project of Tuoxin Team in Henan University of Technology,China(No.2024TXTD11)。
文摘Hard carbon(HC)is a promising anode candidate for sodium-ion batteries(SIBs),yet its application is plagued by unstable interfaces and poor long-term cyclability.Herein,we develop a facile solvent evaporation strategy to synthesize ultrathin Al_(2)O_(3)-coated biomass-derived HC(GSC-Al_(2)O_(3)-3%).The conformal Al_(2)O_(3)layer passivates defects and micropores,suppresses side reactions,and promotes the formation of a robust organic-inorganic hybrid solid electrolyte interphase.Comprehensive characterizations,including in situ X-ray diffraction,ex situ Raman spectra,X-ray photoelectron spectroscopy,time of flight secondary ion mass spectrometry,solid-state 27Al nuclear magnetic resonance,and atomic force microscope modulus mapping,demonstrate that Al_(2)O_(3)actively participates in SEI reconstruction,enhancing the chemical and mechanical stability.Electrochemical tests reveal that the optimized GSC-Al_(2)O_(3)-3%anode delivers 91%capacity retention after 1000 cycles at 1.0 A g^(-1),and possesses excellent wide-temperature tolerance(149.3 mAh g^(-1)at-30℃and 286.8 mAh g^(-1)at 60℃).Mechanistic studies confirm a synergistic Na+storage process involving"adsorption-intercalation-pore filling,"while density functional theory calculations and electrostatic potential mapping reveal that Al_(2)O_(3)coating regulates interfacial charge distribution and reduces Na+migration barriers.A full cell paired with a NaNi_(0.5)Fe_(0.5)MnO_(4)cathode exhibits a high initial capacity of 395.7 mAh g^(-1)and outstanding cycling stability(200 cycles).This work provides fundamental mechanistic insights into interfacial engineering of HC and establishes a cost-effective,scalable route for the next generation highperformance SIBs.
基金Institutional National Research Service Award T32 EY013360(to SM and SW)Research to Prevent Blindness(Career Development Award+8 种基金to PRW)BrightFocus Foundation(National Glaucoma Researchto PRW)Alcon Research Institute(Young Investigator Awardto PRW),and NIH Grants(EY032908,EY035684,EY036111to PRW)the Jefferey T.Fort Innovation Fund and Siteman Retina Research Fund(to RSA)the Hope Center Viral Vectors Core at Washington University School of Medicine,an unrestricted grant(to the Department of Ophthalmology and Visual Sciences)from Research to Prevent BlindnessVision Core Grant(P30 EY002687).
文摘Retinal ganglion cells are susceptible to neurodegenerative conditions and their death drives common forms of irreversible vision loss.In mice,there are 46 transcriptionally unique retinal ganglion cell types that demonstrate different susceptibilities to degeneration.Recent transcriptional experiments defined a novel retinal ganglion cell type that survives particularly well and uniquely expresses high levels of the orphan G-protein-coupled receptor 88.Motivated to study this retinal ganglion cell type,we obtained GPR88-Cre transgenic mice to identify the novel well-surviving retinal ganglion cells and examine their survival and regenerative potential.Our experiments demonstrate that this unidentified retinal ganglion cell type is likely accordant with previously described ON-direction-selective retinal ganglion cells.Interestingly,we find that ON-direction-selective retinal ganglion cells are resilient,but demonstrate limited potential to regenerate their axons in response to well-characterized regenerative treatments.Studying the molecular properties of the ON-direction-selective retinal ganglion cells could unlock new therapeutics to preserve retinal ganglion cells in patients.
文摘The renowned scientist is academician of the Chinese Academy of Sciences,former president of Tsinghua University,and chair of the Tengchong Scientists Forum.ACADEMICIAN of the Chinese Academy of Sciences,former president of Tsinghua University,and chair of the Tengchong Scientists Forum,Gu Binglin is one of the world’s top physicists and materials scientist,and a pioneer in the field of materials design.
