Bangladesh is a deltaic country with a 710 km coastline and numerous newly accreted offshore islands in the central and eastern coastal regions. Natural mangrove forest (the Sundarbans) occupies about 100 km of coastl...Bangladesh is a deltaic country with a 710 km coastline and numerous newly accreted offshore islands in the central and eastern coastal regions. Natural mangrove forest (the Sundarbans) occupies about 100 km of coastline in the southwest, which protects the lives and properties of the coastal population of that area. The depletion of the forest stock of the Sundarbans was reported in 1875 due to the large-scale clearings by the woodcutters and uncertainty in natural regeneration. The restoration of the Sundarbans in the name of enrichment plantation and assisted natural regeneration was formally introduced in 1959 with Excoecaria agallocha followed by the introduction of mangrove and mainland (non-mangrove) species in the moderate to high saline zone and raised lands in the freshwater zone, respectively in 1975. Chakaria Sundarbans, the second largest natural mangrove forest on the east coast, was highly degraded with the rapid expansion of aquaculture between 1976 and 1989. Tremendous human interferences significantly altered the site condition, interrupting natural recovery. Coastal afforestation was initiated in 1966 with two pioneer mangrove species (Sonneratia apetala and Avicennia officinalis). Some afforested sites require attention for restoration due to natural and manmade causes. Bangladesh Forest Department adopted restoration activities with the technical support of the Bangladesh Forest Research Institute and other agencies. However, all the restoration activities for the Sundarbans, Chakaria Sundarbans, and coastal afforested sites had some success and failure stories. The success and failure of a mangrove restoration activity depends on planning (active or passive restoration), selection of suitable sites and species, planting materials, local community involvement, monitoring, evaluation and plantation management.展开更多
In the present study,the mechanical and ballistic properties of friction stir welded(FSW)aluminum alloy(AA5754)samples were investigated,both untreated and cryogenically treated,when impacted by a 7.62 mm armour-pierc...In the present study,the mechanical and ballistic properties of friction stir welded(FSW)aluminum alloy(AA5754)samples were investigated,both untreated and cryogenically treated,when impacted by a 7.62 mm armour-piercing(AP)bullet at an impact velocity of 682±20 m/s.The FSW technique was used to prepare the welded samples for AA5754,with an axial force of 7 kN,a feed rate of 20 mm/min,and a speed of 1200 rpm.The cryogenic treatments performed after welding,including deep cryogenic treatment(DCT)at196℃ and shallow cryogenic treatment(SCT)at80℃,for 6 and 72 h,respectively.The microstructure and mechanical characteristics of cryogenically treated and untreated joints were examined.The cryogenic treatment refined the grain size(1.05 μm)and enhanced the microhardness(93 Hv).Moreover,DCT-FSW significantly improved the tensile strength(13.93%)and impact strength(8.45%)compared to untreated FSW sample.Additionally,in untreated FSW samples,the fracture behaviour varied:the impact fracture mode primarily exhibited ductile failure,while the tensile fracture exhibited a mixed fracture mode.In contrast,the tensile and impact fracture modes of the DCT-FSWwere dominated by a ductile failure mode.The DCT-FSW target demonstrated a lower depth of penetration(DOP)of 31 mm compared to the SCT-FSWand untreated FSW targets.Post-ballistic SEM analysis in the crater region of all three zones revealed the formation of frictional grooves,small cracks,and adiabatic shear bands(ASBs).展开更多
The relation between corresponding trigonometric functions in two rotating coordinate systems is presented. The transformation formula for a vector in the two rotating spherical coordinate systems is obtained. The sca...The relation between corresponding trigonometric functions in two rotating coordinate systems is presented. The transformation formula for a vector in the two rotating spherical coordinate systems is obtained. The scattering fields for a spherical target irradiated by a plane electromagnetic wave in an arbitrary direction are derived. These fields in a particular case retrogress to those available in the literature. The obtained results have great potential in practical applications.展开更多
The study focused on investigating the effect of Deep Cryogenic Treatment(DCT)on the mechanical and ballistic properties of AA7075-T6 aluminum alloy.The microstructure,microhardness,tensile strength,and impact strengt...The study focused on investigating the effect of Deep Cryogenic Treatment(DCT)on the mechanical and ballistic properties of AA7075-T6 aluminum alloy.The microstructure,microhardness,tensile strength,and impact strength of the Base Material(BM)and DCT-treated 7075 samples were analyzed through metallographic analysis and mechanical tests.The microstructure of the DCT-treated 7075 samples revealed fine grains and a distribution of secondary phase particles.The tensile strength,impact strength,and microhardness of DCT-treated samples increased by 7.41%,4%,and 9.68%,respectively,compared to the BM samples.The fractography analysis of the tensile samples showed cleavage facets,microvoids,and dimples in both the samples.The ballistic behavior of the BM and DCT target plates were studied by impacting hard steel core projectiles at a velocity of 750±10 m/s.The target plates failed due to petaling and ductile hole enlargement,and the depth of penetration(DOP)of the DCT target was less than that of the BM target,indicating a higher ballistic resistance.The post-ballistic microstructure examination of the target plates showed the formation of an Adiabatic Shear Band(ASB)without any cracks.It was concluded that the DCT treatment improved the mechanical and ballistic properties of the aluminum alloy due to grain refinement and high dislocation density.展开更多
AIM:To compare the difference of capsulotomy produced by precision pulse capsulotomy(PPC),manual(M-CCC),and femtosecond laser assisted capsulotomy(FLAC)in relation to intraocular lens(IOL)centration,circularity and it...AIM:To compare the difference of capsulotomy produced by precision pulse capsulotomy(PPC),manual(M-CCC),and femtosecond laser assisted capsulotomy(FLAC)in relation to intraocular lens(IOL)centration,circularity and its effect on visual outcomes.METHODS:Prospective,non-randomized comparative study conducted at LV Prasad Eye Institute,Hyderabad,India.Sixty eyes of 52 patients were grouped into 3(FLAC,PPC and M-CCC)based on capsulotomy techniques used.Twenty consecutive eyes with uneventful phacoemulsification and with no comorbidities affecting the capsulotomy or visual outcome were included in each group.The main outcome measure was IOL centration in relation to capsulotomy and pupil.Secondary outcome measures were post-operative visual acuity,manifest refraction and aberration profile between groups.RESULTS:At 5 wk the visual,refractive outcomes and endothelial cell density were comparable between the 3 groups.The median circularity index of FLAC was statistically significantly different to M-CCC or PPC(1-10)groups(P<0.01)but PPC(11-20)was comparable to FLAC.Decentration of IOL center in relation to capsulotomy was seen only between the PPC(1-10)group and FLAC group(P=0.02).The IOL was well centered in relation to the pupil in all the groups(P=0.46).The quality of vision parameters like the higher order aberrations,spherical aberration,coma,trefoil,modular transfer function,and Strehl ratio were comparable between the groups.CONCLUSION:Our study shows that despite differences in the morphology of capsulotomy produced by PPC,M-CCC,FLAC a well-centered IOL can be achieved.The measured capsular morphology parameters do not affect visual outcomes.展开更多
In the November 27,2010 issue of the World Journal of Hepatology (WJH),three case reports were published which involved patients who had consumed various dietary supplements and conventional foods generally marketed a...In the November 27,2010 issue of the World Journal of Hepatology (WJH),three case reports were published which involved patients who had consumed various dietary supplements and conventional foods generally marketed as weight loss products.The reference to Herbalife products as contaminated and generally com-parable to all dietary supplements or weight loss prod-ucts is not scientifically supported.The authors provided an insufficient amount of information regarding patient histories,concomitant medications and other com-pounds,dechallenge results,and product specifications and usage.This information is necessary to fully assess the association of Herbalife products in the WJH case reports.Therefore,the article does not objectively sup-port a causal relationship between the reported cases of liver injury and Herbalife products or ingredients.展开更多
OBJECTIVE: To critically appraise the methodological quality of clinical practice guidelines for headache produced over the last two decades, including those covering specific interventions using Traditional Chinese M...OBJECTIVE: To critically appraise the methodological quality of clinical practice guidelines for headache produced over the last two decades, including those covering specific interventions using Traditional Chinese Medicine.METHODS: The guidelines on headache disorders were obtained by searching a number of databases, including Pub Med, EMBASE, Web of Science,Chinese Biomedical Literature Database, China National Knowledge Infrastructure Database, China Science and Technology Journal Database, and Wanfang database, three guideline-related databases [Guideline-International Network, National Guideline Clearinghouse, and Medlive], and the records of organizations that develop guidelines. The publication date was limited to the period from January 1996 to June 2015. The search terms "headache", "headache disorders", "cephalalgia", "migraine", "tension-type headache", "practice guideline", "consensus ", "statement", "regulation", and "recommendation" were used in the "Me SH" and "Free-text" fields. The guidelines were independently appraised by four researchers using the Appraisal of Guidelines for Research and Evaluation Ⅱ instrument.RESULTS: A total of 23 guidelines published between 1998 and 2014 were reviewed. The overall consistency of the four appraisers was good [interclass correlation coefficient 0.84; 95% confidence interval(CI) 0.82-0.86]. The mean(standard deviation) scores for scope and purpose, stakeholder involvement, rigor of development, clarity of presentation, applicability, and editorial independence were 52.1(18.0), 39.5(17.1), 33.4(21.0), 49.8(21.9),23.8(19.3), and 24.2(23.7). Only two guidelines were recommended, 12 were recommended with modification, and nine were not recommended.CONCLUSION: Physical Traditional Chinese Medicine therapies were recommended to treat headache. The overall quality of headache guidelines was low in China, but evidence-based guidelines are gradually becoming mainstream. Guideline developers should carefully consider, in particular,three domains: rigor of development, applicability,and editorial independence.展开更多
In Japan, the per capita arable land area is small, the natural resources are short, and agricultural production has the typical characteristics of the peasant economy. Even if there are many unfavorable conditions, t...In Japan, the per capita arable land area is small, the natural resources are short, and agricultural production has the typical characteristics of the peasant economy. Even if there are many unfavorable conditions, the level of agricultural modernization of Japan has exceeded that of many developed countries. We conduct comparative analysis on the development characteristics of China's agriculture and Japan's agriculture, and summarize the realization path of Japan's agricultural modernization. Based on the reality of China, we can draw on the following experience from Japan: establishing and improving the agricultural legislation for agriculture; improving the rural cooperative economic organizations; deepening the reform of the agricultural land property right system; increasing the government's direct funds input of into agriculture; improving the agricultural technology extension system.展开更多
The corrosion behavior of 907 steel under thin electrolyte layer(TEL) has been investigated by means of cathodic polarization curve measurement, electrochemical impedance spectroscopy(EIS) and scanning electron micros...The corrosion behavior of 907 steel under thin electrolyte layer(TEL) has been investigated by means of cathodic polarization curve measurement, electrochemical impedance spectroscopy(EIS) and scanning electron microscopy(SEM). The results show that the cathodic diffusion current density presents the variation trend of initial increase and subsequent decrease with the decrease of TEL thickness, and the maximum deposits at 58 μm. The cotangent-hyperbolic impedance(O) is rationally first introduced to study the diffusion process of the reactants through the corrosion products layer with many permeable holes. The initial corrosion rate of 907 steel under different TEL thickness increases with the decrease of TEL thickness except that of 104 μm,whereas the corrosion rate after long time corrosion can be ranked as 104 μm﹥402 μm﹥198 μm﹥301 μm﹥bulk solution.展开更多
Patients with diabetes are more susceptible to coronavirus disease 2019(COVID-19),and as a consequence,develop more severe form of disease.This is partly due to a systemic inflammatory state and pro thrombotic milieu ...Patients with diabetes are more susceptible to coronavirus disease 2019(COVID-19),and as a consequence,develop more severe form of disease.This is partly due to a systemic inflammatory state and pro thrombotic milieu seen in metabolic syndrome.In this review,we attempt to explore the pathogenetic links between insulin resistance and COVID-19 disease severity.Insulin resistance is an underlying condition for metabolic syndromes,including type 2 diabetes,which impairs insulin signaling pathways affecting metabolic and cardiovascular homeostasis.A high concentration of circulating insulin shifts the balance to mitogen activated protein kinase(MAPK)-dependent signaling and causes endothelial cell damage.The phosphatidylinositol 3 kinase and MAPK dependent signaling pathways maintain a balance between nitric oxide-dependent vasodilator and endothelin-1 dependent vasoconstriction actions of insulin.Vascular smooth muscle cell dysfunction is responsible for inflammation and blood coagulation leading to microvascular and macrovascular complications in diabetes.Hyperactivity in renin-angiotensin system is implicated in development of islet oxidative stress and subsequentβ-cell dysfunction,as it alters the islet blood flow.These deleterious effects of insulin resistance involving altered blood pressure,vascular dysfunction,and inflammation could be associated with increased severity in COVID-19 patients.We conclude that clinical and/or biochemical markers of insulin resistance should be included as prognostic markers in assessment of acute COVID-19 disease.展开更多
Polyprenylated acylphloroglucinols represent an important class of natural products found in many plants.Among them,the two related products oblongifolin C(Ob-C)and guttiferone K(Gt-K)isolated from Garcinia species(no...Polyprenylated acylphloroglucinols represent an important class of natural products found in many plants.Among them,the two related products oblongifolin C(Ob-C)and guttiferone K(Gt-K)isolated from Garcinia species(notably from edible fruits),have attracted attention due to their marked anticancer properties.The two compounds only differ by the nature of the C-6 side chain,prenyl(Gt-K)or geranyl(Ob-C)on the phloroglucinol core.Their origin,method of extraction and biological properties are presented here,with a focus on the targets and pathways implicated in their anticancer activities.Both compounds markedly reduce cancer cell proliferation in vitro,as well as tumor growth and metastasis in vivo.They are both potent inducer of tumor cell apoptosis,and regulation of autophagy flux is a hallmark of their mode of action.The distinct mechanism leading to autophagosome accumulation in cells and the implicated molecular targets are discussed.The specific role of the chaperone protein HSPA8,known to interact with Ob-C,is addressed.Molecular models of Gt-K and Ob-C bound to HSPA8 provide a structural basis to their common HSPA8-binding recognition capacity.The review shed light on the mechanism of action of these compounds,to encourage their studies and potential development.展开更多
For sweet cherry, the economic benefit of protected cultivation is much higher than that of open field cultivation. However, problems such as nonuniform germination, aberrant flower, abortion, bad fruit setting and de...For sweet cherry, the economic benefit of protected cultivation is much higher than that of open field cultivation. However, problems such as nonuniform germination, aberrant flower, abortion, bad fruit setting and delayed maturation appear frequently due to the inaccurate regulation of chilling requirement. In order to solve the problems, an automatic system for monitoring, selecting and recording of chilling requirement in protected cultivation of sweet cherry was designed and developed. The system, which consisted of temperature detection, effective chilling temperature selection, signal conversion and output and chilling accumulation display, had been continuously used in protected cultivation of sweet cherry for 3 years and good effects had been achieved. The system monitored chilling accumu- lation accurately and made it more reasonable for the time selection of greenhouse covering, thus avoiding risks of nonuniform germination, bad fruit setting and de- layed maturation, etc. Under the coordinate application of this system with other modern measuring and controlling techniques such as automatic detection and alarming of temperature and humidity, the environment in greenhouses was regulated precisely that the uniform fruits were obtained and the expected yield, quality and harvest time were achieved.展开更多
AIM: To determine the diagnostic accuracy of a new point-of-care assay detecting anti-deamidated gliadin peptides in celiac disease(CD) patients.METHODS: One-hundred-and-twelve patients(age range: 1.8-79.2 years old) ...AIM: To determine the diagnostic accuracy of a new point-of-care assay detecting anti-deamidated gliadin peptides in celiac disease(CD) patients.METHODS: One-hundred-and-twelve patients(age range: 1.8-79.2 years old) with clinical symptoms suggestive of CD and/or first-degree relatives(FDR) of CD patients(n = 66),and confirmed CD on a gluten-free diet(GFD)(n = 46),were prospectively enrolled in the study at Gastroenterology outpatient clinics for adult patients and from the Gastroenterology Consultation Ward at the Pediatric Department of the University Hospital of Geneva.Written informed consent was obtained from all subjects enrolled.The study received approval from the local ethics committee.The original CD diagnosis had been based on serum-positive IgA anti-tissue transglutaminase enzyme-linked immunosorbent assay(ELISA)(QuantaLite,Inova Diagnostics,San Diego,CA,United States) and on biopsy results.Serum samples from all study participants were tested by the new CD lateral flow immunochromatographic assay(CD-LFIA) device,Simtomax Blood Drop(Augurix SA,BioArk,Monthey,Switzerland) to detect immunoglobulin(Ig)A and IgG antibodies against deamidated gliadin peptides.The diagnostic performance was evaluated using receiver operating characteristic curves with 95%CIs.A cut-off of 2 on the Rann colorimetric scale was used to calculate the device's sensitivity and specificity.RESULTS: CD-LFIA was highly accurate in detecting untreated celiac patients.In the group of patients with CD symptoms and/or FDR,eight new cases of CD were detected by ELISA and biopsy.All of these new cases were also correctly identified by CD-LFIA.The test yielded four false positive and four false negative results.The false positive results were all within the groups with clinical symptoms suggestive of CD and/or FDR,whereas the false negative results were all within the GFD group.The test yeld a sensitivity of 78.9%(95%CI: 54.4-93.9) and specificity of 95.7%(95%CI: 89.4-98.8),and the area under the curve reached 0.893(95%CI: 0.798-0.988).The Kappa coefficient,calculated according to the values obtained by two readers from the same device,was of 0.96(SE: 0.06).When the GFD patients were excluded from the analysis,the area under the curve reached 0.989(95%CI: 0.971-1.000) and the Kappa coefficient,calculated according to the values obtained by two readers from the same device,became 0.96(SE: 0.07).Furthermore,using the Rann scale cut-off of 2 without the GFD patients,sensitivity was 100% and specificity was 93.1%(95%CI: 83.3-98.1).CONCLUSION: The new CD-LFIA rapid screening test shows good diagnostic accuracy,sensitivity and specificity,and may rule out CD in patients with CD-related symptoms.展开更多
Qu Yuan is one of the famous patriotic poets in the history of China,and as for his poems,they shall not only be interpreted from the literary perspective but also from the political perspective,because it is a tradit...Qu Yuan is one of the famous patriotic poets in the history of China,and as for his poems,they shall not only be interpreted from the literary perspective but also from the political perspective,because it is a tradition that poets tend to express their am bition through poems. In the poems of Qu Yuan,we can read both the thoughts about the country and about his own life. The ideal personality and the ideal politics are inseparable,the former of which is the foundation while the later the supreme goal. The integration of the ideal personality and the ideal politics is the essence of the patriotism of Qu Yuan,which,for the later generations,is still worthem phasizing and researching.展开更多
Single nucleotide polymorphisms and restriction digestion-based haplotype variations among 160 flood prone rice varieties were analyzed with enzymes Alu I and Cac8 I to generate polymorphisms at Sub1A and Sub1C loci ...Single nucleotide polymorphisms and restriction digestion-based haplotype variations among 160 flood prone rice varieties were analyzed with enzymes Alu I and Cac8 I to generate polymorphisms at Sub1A and Sub1C loci （conferring submergence tolerance）, respectively. Haplotype associated with phenotype was used to study the haplotype variations at Sub1A and Sub1C loci and to determine their functional influence on submergence tolerance and stem elongation. Three patterns at Sub1A locus, Sub1A0 （null allele）, Sub1A1 （does not cut） and Sub1A2 （one SNP）, and four patterns at Sub1C locus, Sub1C1, Sub1C2, Sub1C3 and Sub1C4, were generated. Both tolerant Sub1A1 and intolerant Sub1A2 had the same length, but the difference was presence of a restriction site in the Sub1A2, but absent at the Sub1A1. Further, two types of polymorphism were detected at the Sub1C, one included major length polymorphisms （165, 170 and 175 bp） and the other was a single restriction site at different position. Eight haplotypes （different combinations of the two loci）, A1C1, A1C2, A1C4, A2C2, A2C4, A0C2, A0C3 and A0C4, were detected among 160 varieties. Haplotype A1C1 was comparatively more related to haplotypes A1C2 and A1C4, having the same Sub1A allele, and these haplotypes were found only in Bangladeshi, Sri Lankan and Indian varieties. Most tolerant varieties in A1C1 haplotype showed slow elongation, having tolerant specific Sub1A1 and Sub1C1 alleles. Further, the varieties Madabaru and Kottamali （A2C2） also showed moderate level of tolerance without Sub1A1 allele. These varieties were different with FR13A and also suspected to carry different novel tolerant genes at other loci. These materials could be used for hybridization with Sub1 varieties for pyramiding additional tolerant specific alleles into a single genotype for improving submergence tolerance in rice.展开更多
Based on results of previous studies,through investigations,the status quo,main advantages and disadvantages of using small hand-power scutchers and large-scale automatic sisal production lines to process sisal fiber ...Based on results of previous studies,through investigations,the status quo,main advantages and disadvantages of using small hand-power scutchers and large-scale automatic sisal production lines to process sisal fiber were summarized and analyzed; the traditional uses and latest products of sisal fiber were studied,especially the comprehensive utilization of byproducts produced during sisal fiber processing as well as the broad prospects of new sisal products.展开更多
Human dresses are different in thousands way. Human body image signals have big noise, a poor light and shade contrast and a narrow range of gray gradation distribution. The application of a traditional grads method o...Human dresses are different in thousands way. Human body image signals have big noise, a poor light and shade contrast and a narrow range of gray gradation distribution. The application of a traditional grads method or gray method to detect human body image edges can't obtain satisfactory results because of false detections and missed detections. According to the peculiarity of human body image, dyadic wavelet transform of cubic spline is successfully applied to detect the face and profile edges of human body image and Mallat algorithm is used in the wavelet decomposition in this paper.展开更多
Black cumin (Nigella sativa L.;Family-Ranunculaceae) is an important spice crop. Mature seeds are consumed for edible and medical purposes and also used as a food additive and flavour. Seed of black cumin has great po...Black cumin (Nigella sativa L.;Family-Ranunculaceae) is an important spice crop. Mature seeds are consumed for edible and medical purposes and also used as a food additive and flavour. Seed of black cumin has great potentiality as spice crop due to nutritive and medicinal values. The experiments were carried out at Bangabandhu Sheikh Mujibur Rahman Agricultural University, Gazipur during 2011 to 2012 to determine optimum planting time for seed production of black cumin. The experiment was two factorials. Factor A: 4 genotypes were V1: Exotic, Iran;V2: BARI kalozira-1;V3: Local, Faridpur and V4: Local, Natore. Factor B: sowing date: D1: 16 October;D2: 1 November;D3: 16 November and D4: 1 December. Therefore, treatment combinations were 16 in total. So, in 3 replications total plot was 48. Result revealed that significantly the highest 2.37 t/ha in V1, followed by V2 (1.96 t/ha). V2 and V3 (1.97 t/ha) were statistically similar and maximum yield was obtained from D2 (2.65 t/ha). In combined effect, maximum yield 3.00 t/ha was obtained in V1D2.. Investigation on time of sowing revealed that performance of black cumin was better in earlier sowings (16 October, 1 November) than later ones. The highest yield (4g plant-1;2.65 tha-1) was obtained when the crop was sown on 1 November. Among the genotypes, the exotic one with sowing in 1 November gave the highest seed yield (4.54 g·plant-1;3.00 t·ha-1).展开更多
文摘Bangladesh is a deltaic country with a 710 km coastline and numerous newly accreted offshore islands in the central and eastern coastal regions. Natural mangrove forest (the Sundarbans) occupies about 100 km of coastline in the southwest, which protects the lives and properties of the coastal population of that area. The depletion of the forest stock of the Sundarbans was reported in 1875 due to the large-scale clearings by the woodcutters and uncertainty in natural regeneration. The restoration of the Sundarbans in the name of enrichment plantation and assisted natural regeneration was formally introduced in 1959 with Excoecaria agallocha followed by the introduction of mangrove and mainland (non-mangrove) species in the moderate to high saline zone and raised lands in the freshwater zone, respectively in 1975. Chakaria Sundarbans, the second largest natural mangrove forest on the east coast, was highly degraded with the rapid expansion of aquaculture between 1976 and 1989. Tremendous human interferences significantly altered the site condition, interrupting natural recovery. Coastal afforestation was initiated in 1966 with two pioneer mangrove species (Sonneratia apetala and Avicennia officinalis). Some afforested sites require attention for restoration due to natural and manmade causes. Bangladesh Forest Department adopted restoration activities with the technical support of the Bangladesh Forest Research Institute and other agencies. However, all the restoration activities for the Sundarbans, Chakaria Sundarbans, and coastal afforested sites had some success and failure stories. The success and failure of a mangrove restoration activity depends on planning (active or passive restoration), selection of suitable sites and species, planting materials, local community involvement, monitoring, evaluation and plantation management.
文摘In the present study,the mechanical and ballistic properties of friction stir welded(FSW)aluminum alloy(AA5754)samples were investigated,both untreated and cryogenically treated,when impacted by a 7.62 mm armour-piercing(AP)bullet at an impact velocity of 682±20 m/s.The FSW technique was used to prepare the welded samples for AA5754,with an axial force of 7 kN,a feed rate of 20 mm/min,and a speed of 1200 rpm.The cryogenic treatments performed after welding,including deep cryogenic treatment(DCT)at196℃ and shallow cryogenic treatment(SCT)at80℃,for 6 and 72 h,respectively.The microstructure and mechanical characteristics of cryogenically treated and untreated joints were examined.The cryogenic treatment refined the grain size(1.05 μm)and enhanced the microhardness(93 Hv).Moreover,DCT-FSW significantly improved the tensile strength(13.93%)and impact strength(8.45%)compared to untreated FSW sample.Additionally,in untreated FSW samples,the fracture behaviour varied:the impact fracture mode primarily exhibited ductile failure,while the tensile fracture exhibited a mixed fracture mode.In contrast,the tensile and impact fracture modes of the DCT-FSWwere dominated by a ductile failure mode.The DCT-FSW target demonstrated a lower depth of penetration(DOP)of 31 mm compared to the SCT-FSWand untreated FSW targets.Post-ballistic SEM analysis in the crater region of all three zones revealed the formation of frictional grooves,small cracks,and adiabatic shear bands(ASBs).
基金Project supported by the National Natural Science Foundation of China （Grant No 60171010）, and the Education 0ffice of Shaaxi Province （Grant No 03JK070）.
文摘The relation between corresponding trigonometric functions in two rotating coordinate systems is presented. The transformation formula for a vector in the two rotating spherical coordinate systems is obtained. The scattering fields for a spherical target irradiated by a plane electromagnetic wave in an arbitrary direction are derived. These fields in a particular case retrogress to those available in the literature. The obtained results have great potential in practical applications.
文摘The study focused on investigating the effect of Deep Cryogenic Treatment(DCT)on the mechanical and ballistic properties of AA7075-T6 aluminum alloy.The microstructure,microhardness,tensile strength,and impact strength of the Base Material(BM)and DCT-treated 7075 samples were analyzed through metallographic analysis and mechanical tests.The microstructure of the DCT-treated 7075 samples revealed fine grains and a distribution of secondary phase particles.The tensile strength,impact strength,and microhardness of DCT-treated samples increased by 7.41%,4%,and 9.68%,respectively,compared to the BM samples.The fractography analysis of the tensile samples showed cleavage facets,microvoids,and dimples in both the samples.The ballistic behavior of the BM and DCT target plates were studied by impacting hard steel core projectiles at a velocity of 750±10 m/s.The target plates failed due to petaling and ductile hole enlargement,and the depth of penetration(DOP)of the DCT target was less than that of the BM target,indicating a higher ballistic resistance.The post-ballistic microstructure examination of the target plates showed the formation of an Adiabatic Shear Band(ASB)without any cracks.It was concluded that the DCT treatment improved the mechanical and ballistic properties of the aluminum alloy due to grain refinement and high dislocation density.
基金Supported by Hyderabad Eye Research Foundation(HERF),Hyderabad,Telangana,India。
文摘AIM:To compare the difference of capsulotomy produced by precision pulse capsulotomy(PPC),manual(M-CCC),and femtosecond laser assisted capsulotomy(FLAC)in relation to intraocular lens(IOL)centration,circularity and its effect on visual outcomes.METHODS:Prospective,non-randomized comparative study conducted at LV Prasad Eye Institute,Hyderabad,India.Sixty eyes of 52 patients were grouped into 3(FLAC,PPC and M-CCC)based on capsulotomy techniques used.Twenty consecutive eyes with uneventful phacoemulsification and with no comorbidities affecting the capsulotomy or visual outcome were included in each group.The main outcome measure was IOL centration in relation to capsulotomy and pupil.Secondary outcome measures were post-operative visual acuity,manifest refraction and aberration profile between groups.RESULTS:At 5 wk the visual,refractive outcomes and endothelial cell density were comparable between the 3 groups.The median circularity index of FLAC was statistically significantly different to M-CCC or PPC(1-10)groups(P<0.01)but PPC(11-20)was comparable to FLAC.Decentration of IOL center in relation to capsulotomy was seen only between the PPC(1-10)group and FLAC group(P=0.02).The IOL was well centered in relation to the pupil in all the groups(P=0.46).The quality of vision parameters like the higher order aberrations,spherical aberration,coma,trefoil,modular transfer function,and Strehl ratio were comparable between the groups.CONCLUSION:Our study shows that despite differences in the morphology of capsulotomy produced by PPC,M-CCC,FLAC a well-centered IOL can be achieved.The measured capsular morphology parameters do not affect visual outcomes.
文摘In the November 27,2010 issue of the World Journal of Hepatology (WJH),three case reports were published which involved patients who had consumed various dietary supplements and conventional foods generally marketed as weight loss products.The reference to Herbalife products as contaminated and generally com-parable to all dietary supplements or weight loss prod-ucts is not scientifically supported.The authors provided an insufficient amount of information regarding patient histories,concomitant medications and other com-pounds,dechallenge results,and product specifications and usage.This information is necessary to fully assess the association of Herbalife products in the WJH case reports.Therefore,the article does not objectively sup-port a causal relationship between the reported cases of liver injury and Herbalife products or ingredients.
基金Supported by the Special Research Project of Traditional Chinese Medicine of Guangdong Hospital of Chinese Medicine(No.YN2015MS22)the Science planning project of Guangzhou(No.2014Y2-00040)
文摘OBJECTIVE: To critically appraise the methodological quality of clinical practice guidelines for headache produced over the last two decades, including those covering specific interventions using Traditional Chinese Medicine.METHODS: The guidelines on headache disorders were obtained by searching a number of databases, including Pub Med, EMBASE, Web of Science,Chinese Biomedical Literature Database, China National Knowledge Infrastructure Database, China Science and Technology Journal Database, and Wanfang database, three guideline-related databases [Guideline-International Network, National Guideline Clearinghouse, and Medlive], and the records of organizations that develop guidelines. The publication date was limited to the period from January 1996 to June 2015. The search terms "headache", "headache disorders", "cephalalgia", "migraine", "tension-type headache", "practice guideline", "consensus ", "statement", "regulation", and "recommendation" were used in the "Me SH" and "Free-text" fields. The guidelines were independently appraised by four researchers using the Appraisal of Guidelines for Research and Evaluation Ⅱ instrument.RESULTS: A total of 23 guidelines published between 1998 and 2014 were reviewed. The overall consistency of the four appraisers was good [interclass correlation coefficient 0.84; 95% confidence interval(CI) 0.82-0.86]. The mean(standard deviation) scores for scope and purpose, stakeholder involvement, rigor of development, clarity of presentation, applicability, and editorial independence were 52.1(18.0), 39.5(17.1), 33.4(21.0), 49.8(21.9),23.8(19.3), and 24.2(23.7). Only two guidelines were recommended, 12 were recommended with modification, and nine were not recommended.CONCLUSION: Physical Traditional Chinese Medicine therapies were recommended to treat headache. The overall quality of headache guidelines was low in China, but evidence-based guidelines are gradually becoming mainstream. Guideline developers should carefully consider, in particular,three domains: rigor of development, applicability,and editorial independence.
基金Supported by Shandong Social Science Planning Project(07CSHZ05)
文摘In Japan, the per capita arable land area is small, the natural resources are short, and agricultural production has the typical characteristics of the peasant economy. Even if there are many unfavorable conditions, the level of agricultural modernization of Japan has exceeded that of many developed countries. We conduct comparative analysis on the development characteristics of China's agriculture and Japan's agriculture, and summarize the realization path of Japan's agricultural modernization. Based on the reality of China, we can draw on the following experience from Japan: establishing and improving the agricultural legislation for agriculture; improving the rural cooperative economic organizations; deepening the reform of the agricultural land property right system; increasing the government's direct funds input of into agriculture; improving the agricultural technology extension system.
基金Projects(21073162,21273199) supported by the National Natural Science Foundation of ChinaProject(GCTKF2012013) supported by the Science and Technology Bureau of Jiaxing Municipality and the State Key Laboratory Breeding Base of Green Chemistry-Synthesis Technology,China
文摘The corrosion behavior of 907 steel under thin electrolyte layer(TEL) has been investigated by means of cathodic polarization curve measurement, electrochemical impedance spectroscopy(EIS) and scanning electron microscopy(SEM). The results show that the cathodic diffusion current density presents the variation trend of initial increase and subsequent decrease with the decrease of TEL thickness, and the maximum deposits at 58 μm. The cotangent-hyperbolic impedance(O) is rationally first introduced to study the diffusion process of the reactants through the corrosion products layer with many permeable holes. The initial corrosion rate of 907 steel under different TEL thickness increases with the decrease of TEL thickness except that of 104 μm,whereas the corrosion rate after long time corrosion can be ranked as 104 μm﹥402 μm﹥198 μm﹥301 μm﹥bulk solution.
文摘Patients with diabetes are more susceptible to coronavirus disease 2019(COVID-19),and as a consequence,develop more severe form of disease.This is partly due to a systemic inflammatory state and pro thrombotic milieu seen in metabolic syndrome.In this review,we attempt to explore the pathogenetic links between insulin resistance and COVID-19 disease severity.Insulin resistance is an underlying condition for metabolic syndromes,including type 2 diabetes,which impairs insulin signaling pathways affecting metabolic and cardiovascular homeostasis.A high concentration of circulating insulin shifts the balance to mitogen activated protein kinase(MAPK)-dependent signaling and causes endothelial cell damage.The phosphatidylinositol 3 kinase and MAPK dependent signaling pathways maintain a balance between nitric oxide-dependent vasodilator and endothelin-1 dependent vasoconstriction actions of insulin.Vascular smooth muscle cell dysfunction is responsible for inflammation and blood coagulation leading to microvascular and macrovascular complications in diabetes.Hyperactivity in renin-angiotensin system is implicated in development of islet oxidative stress and subsequentβ-cell dysfunction,as it alters the islet blood flow.These deleterious effects of insulin resistance involving altered blood pressure,vascular dysfunction,and inflammation could be associated with increased severity in COVID-19 patients.We conclude that clinical and/or biochemical markers of insulin resistance should be included as prognostic markers in assessment of acute COVID-19 disease.
文摘Polyprenylated acylphloroglucinols represent an important class of natural products found in many plants.Among them,the two related products oblongifolin C(Ob-C)and guttiferone K(Gt-K)isolated from Garcinia species(notably from edible fruits),have attracted attention due to their marked anticancer properties.The two compounds only differ by the nature of the C-6 side chain,prenyl(Gt-K)or geranyl(Ob-C)on the phloroglucinol core.Their origin,method of extraction and biological properties are presented here,with a focus on the targets and pathways implicated in their anticancer activities.Both compounds markedly reduce cancer cell proliferation in vitro,as well as tumor growth and metastasis in vivo.They are both potent inducer of tumor cell apoptosis,and regulation of autophagy flux is a hallmark of their mode of action.The distinct mechanism leading to autophagosome accumulation in cells and the implicated molecular targets are discussed.The specific role of the chaperone protein HSPA8,known to interact with Ob-C,is addressed.Molecular models of Gt-K and Ob-C bound to HSPA8 provide a structural basis to their common HSPA8-binding recognition capacity.The review shed light on the mechanism of action of these compounds,to encourage their studies and potential development.
基金Supported by"New variety breeding of Sweet Cherry"belongs to National Science-technology Support Plan Projects for the 12th Five-Year Plan(2013BAD02B03-3-2)"948"Project of Agricultural Department(2011-Z40)+2 种基金Special Fund for Fruit Innovation Team of Modern Agricultural Industry Technology System in Shandong Province(SDAIT-03-022-04)Shandong Agricultural Engineering Project of Improved Variety(2013)"Introduction of Excellent Fruit Germplasm Resource and Germplasm Bank"belongs to National Science and Technology Cooperation Projects(2012DFR30700)
文摘For sweet cherry, the economic benefit of protected cultivation is much higher than that of open field cultivation. However, problems such as nonuniform germination, aberrant flower, abortion, bad fruit setting and delayed maturation appear frequently due to the inaccurate regulation of chilling requirement. In order to solve the problems, an automatic system for monitoring, selecting and recording of chilling requirement in protected cultivation of sweet cherry was designed and developed. The system, which consisted of temperature detection, effective chilling temperature selection, signal conversion and output and chilling accumulation display, had been continuously used in protected cultivation of sweet cherry for 3 years and good effects had been achieved. The system monitored chilling accumu- lation accurately and made it more reasonable for the time selection of greenhouse covering, thus avoiding risks of nonuniform germination, bad fruit setting and de- layed maturation, etc. Under the coordinate application of this system with other modern measuring and controlling techniques such as automatic detection and alarming of temperature and humidity, the environment in greenhouses was regulated precisely that the uniform fruits were obtained and the expected yield, quality and harvest time were achieved.
基金Supported by the Swiss Celiac Association,Association Romande de Coeliakie,No.ME 8309 awarded to Sch ppi MG
文摘AIM: To determine the diagnostic accuracy of a new point-of-care assay detecting anti-deamidated gliadin peptides in celiac disease(CD) patients.METHODS: One-hundred-and-twelve patients(age range: 1.8-79.2 years old) with clinical symptoms suggestive of CD and/or first-degree relatives(FDR) of CD patients(n = 66),and confirmed CD on a gluten-free diet(GFD)(n = 46),were prospectively enrolled in the study at Gastroenterology outpatient clinics for adult patients and from the Gastroenterology Consultation Ward at the Pediatric Department of the University Hospital of Geneva.Written informed consent was obtained from all subjects enrolled.The study received approval from the local ethics committee.The original CD diagnosis had been based on serum-positive IgA anti-tissue transglutaminase enzyme-linked immunosorbent assay(ELISA)(QuantaLite,Inova Diagnostics,San Diego,CA,United States) and on biopsy results.Serum samples from all study participants were tested by the new CD lateral flow immunochromatographic assay(CD-LFIA) device,Simtomax Blood Drop(Augurix SA,BioArk,Monthey,Switzerland) to detect immunoglobulin(Ig)A and IgG antibodies against deamidated gliadin peptides.The diagnostic performance was evaluated using receiver operating characteristic curves with 95%CIs.A cut-off of 2 on the Rann colorimetric scale was used to calculate the device's sensitivity and specificity.RESULTS: CD-LFIA was highly accurate in detecting untreated celiac patients.In the group of patients with CD symptoms and/or FDR,eight new cases of CD were detected by ELISA and biopsy.All of these new cases were also correctly identified by CD-LFIA.The test yielded four false positive and four false negative results.The false positive results were all within the groups with clinical symptoms suggestive of CD and/or FDR,whereas the false negative results were all within the GFD group.The test yeld a sensitivity of 78.9%(95%CI: 54.4-93.9) and specificity of 95.7%(95%CI: 89.4-98.8),and the area under the curve reached 0.893(95%CI: 0.798-0.988).The Kappa coefficient,calculated according to the values obtained by two readers from the same device,was of 0.96(SE: 0.06).When the GFD patients were excluded from the analysis,the area under the curve reached 0.989(95%CI: 0.971-1.000) and the Kappa coefficient,calculated according to the values obtained by two readers from the same device,became 0.96(SE: 0.07).Furthermore,using the Rann scale cut-off of 2 without the GFD patients,sensitivity was 100% and specificity was 93.1%(95%CI: 83.3-98.1).CONCLUSION: The new CD-LFIA rapid screening test shows good diagnostic accuracy,sensitivity and specificity,and may rule out CD in patients with CD-related symptoms.
文摘Qu Yuan is one of the famous patriotic poets in the history of China,and as for his poems,they shall not only be interpreted from the literary perspective but also from the political perspective,because it is a tradition that poets tend to express their am bition through poems. In the poems of Qu Yuan,we can read both the thoughts about the country and about his own life. The ideal personality and the ideal politics are inseparable,the former of which is the foundation while the later the supreme goal. The integration of the ideal personality and the ideal politics is the essence of the patriotism of Qu Yuan,which,for the later generations,is still worthem phasizing and researching.
文摘Single nucleotide polymorphisms and restriction digestion-based haplotype variations among 160 flood prone rice varieties were analyzed with enzymes Alu I and Cac8 I to generate polymorphisms at Sub1A and Sub1C loci （conferring submergence tolerance）, respectively. Haplotype associated with phenotype was used to study the haplotype variations at Sub1A and Sub1C loci and to determine their functional influence on submergence tolerance and stem elongation. Three patterns at Sub1A locus, Sub1A0 （null allele）, Sub1A1 （does not cut） and Sub1A2 （one SNP）, and four patterns at Sub1C locus, Sub1C1, Sub1C2, Sub1C3 and Sub1C4, were generated. Both tolerant Sub1A1 and intolerant Sub1A2 had the same length, but the difference was presence of a restriction site in the Sub1A2, but absent at the Sub1A1. Further, two types of polymorphism were detected at the Sub1C, one included major length polymorphisms （165, 170 and 175 bp） and the other was a single restriction site at different position. Eight haplotypes （different combinations of the two loci）, A1C1, A1C2, A1C4, A2C2, A2C4, A0C2, A0C3 and A0C4, were detected among 160 varieties. Haplotype A1C1 was comparatively more related to haplotypes A1C2 and A1C4, having the same Sub1A allele, and these haplotypes were found only in Bangladeshi, Sri Lankan and Indian varieties. Most tolerant varieties in A1C1 haplotype showed slow elongation, having tolerant specific Sub1A1 and Sub1C1 alleles. Further, the varieties Madabaru and Kottamali （A2C2） also showed moderate level of tolerance without Sub1A1 allele. These varieties were different with FR13A and also suspected to carry different novel tolerant genes at other loci. These materials could be used for hybridization with Sub1 varieties for pyramiding additional tolerant specific alleles into a single genotype for improving submergence tolerance in rice.
文摘Based on results of previous studies,through investigations,the status quo,main advantages and disadvantages of using small hand-power scutchers and large-scale automatic sisal production lines to process sisal fiber were summarized and analyzed; the traditional uses and latest products of sisal fiber were studied,especially the comprehensive utilization of byproducts produced during sisal fiber processing as well as the broad prospects of new sisal products.
基金This work was supported by the natural science foundation of Henan province(004061000)
文摘Human dresses are different in thousands way. Human body image signals have big noise, a poor light and shade contrast and a narrow range of gray gradation distribution. The application of a traditional grads method or gray method to detect human body image edges can't obtain satisfactory results because of false detections and missed detections. According to the peculiarity of human body image, dyadic wavelet transform of cubic spline is successfully applied to detect the face and profile edges of human body image and Mallat algorithm is used in the wavelet decomposition in this paper.
文摘Black cumin (Nigella sativa L.;Family-Ranunculaceae) is an important spice crop. Mature seeds are consumed for edible and medical purposes and also used as a food additive and flavour. Seed of black cumin has great potentiality as spice crop due to nutritive and medicinal values. The experiments were carried out at Bangabandhu Sheikh Mujibur Rahman Agricultural University, Gazipur during 2011 to 2012 to determine optimum planting time for seed production of black cumin. The experiment was two factorials. Factor A: 4 genotypes were V1: Exotic, Iran;V2: BARI kalozira-1;V3: Local, Faridpur and V4: Local, Natore. Factor B: sowing date: D1: 16 October;D2: 1 November;D3: 16 November and D4: 1 December. Therefore, treatment combinations were 16 in total. So, in 3 replications total plot was 48. Result revealed that significantly the highest 2.37 t/ha in V1, followed by V2 (1.96 t/ha). V2 and V3 (1.97 t/ha) were statistically similar and maximum yield was obtained from D2 (2.65 t/ha). In combined effect, maximum yield 3.00 t/ha was obtained in V1D2.. Investigation on time of sowing revealed that performance of black cumin was better in earlier sowings (16 October, 1 November) than later ones. The highest yield (4g plant-1;2.65 tha-1) was obtained when the crop was sown on 1 November. Among the genotypes, the exotic one with sowing in 1 November gave the highest seed yield (4.54 g·plant-1;3.00 t·ha-1).
