Bituminous rocks in the Ozankoey （Ankara） field are different from those of the Paleocene- Eocene Mengen and Giineytepe （Bolu） regions in metal enrichment levels. Organic carbon （Corg） content of organic materia...Bituminous rocks in the Ozankoey （Ankara） field are different from those of the Paleocene- Eocene Mengen and Giineytepe （Bolu） regions in metal enrichment levels. Organic carbon （Corg） content of organic material-rich rocks in the Ozankoey （Ankara） field is 3.66-40.72% wt averaging 14.34%. The dominant organic materials are algae/amorphous accompanied by minor amount of herbaceous material （The dominant kerogen type is Type-I with a limited amount of Type-Ⅱ kerogen.）. The bituminous rocks in the Ozankoey field are enriched in heavy metals such as Ni, Mn, As and Cr. In comparison with the average enrichment values of dements, Ni, Mn, As and Cr in bituminous shales of the Ozankoey field are as about 4.38, 14.93, 10.90 and 5.58 times as average values. The average concentrations of these heavy metals are also as high as 215× 10^-6, 828 × 10^-6, 58.54 × 10^-6, and 148 × 10^-6 respectively. In addition, sorption properties of day and organic materials are also important for metal enrichments in the bituminous shales.展开更多
Boronic acid compounds with different substituted groups were handled to synthesize various ligands encoded as B1, B2, B3, B4, BS, B6, B7 and BS. B5 and B7 were tested for the cytotoxic activity against the prostate c...Boronic acid compounds with different substituted groups were handled to synthesize various ligands encoded as B1, B2, B3, B4, BS, B6, B7 and BS. B5 and B7 were tested for the cytotoxic activity against the prostate cancer cells and it was found that the cell viability of cancer cells was decreased while most of the healthy cells could still be viable. 5 μM solutions of B5 and B7 decreased the cell viability to 33% and 44%; whereas healthy cells were 71% and 95%, respectively, after treatment. Antimicrobial properties were explored against the bacterial and fungal microorganisms with B1, B5 and BZ The inhibition zones were evaluated for all boronic structures, and the growth inhibition zones were determined in a range of 7-13 mm diameter for different microorganism species. Staphylococcus aureus was the common micro- organism that three boronic compounds with imine ligands showed the activity. Antioxidant features of B2, B3, B4, B5, B6, B7 and B8 were investigated by different processes such as Beta-carotene bleaching （BCB）, 2,2-diphenyl picryl hydrazyl （DPPH）, 2,2″-azino-bis（ 3-ethylbenzothiazoline-6-sulphonic acid） （ABTS） and CUPric reducing antioxidant capacity （CLIPRAC） methods. Significant antioxidant activity was achieved by the phenyl boronic based ligands and these compounds demonstrated as much activity as standards （α-Toc and BHT）. In addition, all structures were applied properly without any decomposition during the experiments. They were rather stable both in aqueous media and solid state.展开更多
Objective:To assess the acute and subacute toxicity as well as the phytochemical composition of two extracts and three fractions of Ammi majus L.Methods:The aqueous extracts were prepared separately by maceration for ...Objective:To assess the acute and subacute toxicity as well as the phytochemical composition of two extracts and three fractions of Ammi majus L.Methods:The aqueous extracts were prepared separately by maceration for 48 h and by infusion for 1 h,while the fractions were prepared by the Soxhlet extractor,successively employing cyclohexane,ethyl acetate,and ethanol.The acute toxicity study was carried out in accordance with the OECD N°423 guideline at a single dose(2000 mg/kg)in mice for 14 days.The subacute toxicity study was performed by a daily oral administration of 250 mg/kg 2 for 10 d and 100 mg/kg doses for 28 d.Phytochemical screening was performed using staining and precipitation reactions,while the chemical characterization of some analytes was detected by HPLC-MS/MS analysis.Results:In the acute toxicity study,no signs of toxicity such as convulsion,salivation,diarrhea,sleep and coma were observed during 30 minutes and 14 days,so the lethal dose was higher than 2000 mg/kg for each extract and fraction.The subacute toxicity results showed that at a dose of 250 mg/kg,61.10%of the animals died and the rest developed morbidity.On the other hand,at a dose of 100 mg/kg,all the animals were still alive after 28 days,with no morbidity and the biochemical parameters were normal with no abnormalities in the liver,kidneys and pancreas.Phytochemical screening indicated the presence of flavonoids,tannins,coumarins,and free quinones and the absence of alkaloids and anthocyanins.Conclusions:The extracts and fractions of Ammi majus L.are not toxic in the short and long term with a varied chemical composition.Toxicological tests on animals other than rodents and in the long term(more than 28 days)are needed to further confirm the safety of Ammi majus extracts.展开更多
The objective of this study is to determine the geochemical role of molluscs in the distribution of uranium in the marine ecosystem. Biogeochemical studies are carried out on recent mollusc shells from the Caspian Sea...The objective of this study is to determine the geochemical role of molluscs in the distribution of uranium in the marine ecosystem. Biogeochemical studies are carried out on recent mollusc shells from the Caspian Sea, Sea of Japan, Sea of Marmara, Aegean Sea, Black Sea, Mediterranean Sea, Baltic Sea, and Indian Ocean, which differ from each other in terms of physical, chemical, geographic, and geochemical characteristics. In this study, nine Gastropoda and fifty-four Pelecypoda shells of different species are analyzed to document variations of uranium in seasonal layers, which were formed by the seasonal carbonate-organic phase of molluscs during their entire lives. Shell used in this study principally comprises three layers: upper (outer) prismatic, middle prismatic, and inner (mother-of-pearl) layers. In addition, when possible, the head, the middle, and the lower parts of the shells are used for analyses separately. Also, the biological accumulation rate values for each different mollusc species rel展开更多
In this study, Ultra High Performance Electrospray Ionization Ion Trap Time of Flight Mass Spectrometry （UHPLC-ESI-1T-TOF MS） method is used to screen the polymer additives in drinking water that is stored in Polyet...In this study, Ultra High Performance Electrospray Ionization Ion Trap Time of Flight Mass Spectrometry （UHPLC-ESI-1T-TOF MS） method is used to screen the polymer additives in drinking water that is stored in Polyethylene Terephthalate （PET） bottles. After directly analyzing the commercially available water samples, 3 polymer additives （chimassorb 81, irgafos 168 and oleamide） were detected. However, after exposure to sunshine for 8 days, two additional polymer additives （antioxidant 2246 and Butylated Hydroxytoluene （BHT）） were detected besides the former three additives.展开更多
文摘Bituminous rocks in the Ozankoey （Ankara） field are different from those of the Paleocene- Eocene Mengen and Giineytepe （Bolu） regions in metal enrichment levels. Organic carbon （Corg） content of organic material-rich rocks in the Ozankoey （Ankara） field is 3.66-40.72% wt averaging 14.34%. The dominant organic materials are algae/amorphous accompanied by minor amount of herbaceous material （The dominant kerogen type is Type-I with a limited amount of Type-Ⅱ kerogen.）. The bituminous rocks in the Ozankoey field are enriched in heavy metals such as Ni, Mn, As and Cr. In comparison with the average enrichment values of dements, Ni, Mn, As and Cr in bituminous shales of the Ozankoey field are as about 4.38, 14.93, 10.90 and 5.58 times as average values. The average concentrations of these heavy metals are also as high as 215× 10^-6, 828 × 10^-6, 58.54 × 10^-6, and 148 × 10^-6 respectively. In addition, sorption properties of day and organic materials are also important for metal enrichments in the bituminous shales.
基金Dicle University Science and Technology Research Center(DUBTAM)Dicle University Scientific and Technological Research Council(DUBAP)with Grant Number:14–EZF–14 are gratefully acknowledged for their analysis and financial supports
文摘Boronic acid compounds with different substituted groups were handled to synthesize various ligands encoded as B1, B2, B3, B4, BS, B6, B7 and BS. B5 and B7 were tested for the cytotoxic activity against the prostate cancer cells and it was found that the cell viability of cancer cells was decreased while most of the healthy cells could still be viable. 5 μM solutions of B5 and B7 decreased the cell viability to 33% and 44%; whereas healthy cells were 71% and 95%, respectively, after treatment. Antimicrobial properties were explored against the bacterial and fungal microorganisms with B1, B5 and BZ The inhibition zones were evaluated for all boronic structures, and the growth inhibition zones were determined in a range of 7-13 mm diameter for different microorganism species. Staphylococcus aureus was the common micro- organism that three boronic compounds with imine ligands showed the activity. Antioxidant features of B2, B3, B4, B5, B6, B7 and B8 were investigated by different processes such as Beta-carotene bleaching （BCB）, 2,2-diphenyl picryl hydrazyl （DPPH）, 2,2″-azino-bis（ 3-ethylbenzothiazoline-6-sulphonic acid） （ABTS） and CUPric reducing antioxidant capacity （CLIPRAC） methods. Significant antioxidant activity was achieved by the phenyl boronic based ligands and these compounds demonstrated as much activity as standards （α-Toc and BHT）. In addition, all structures were applied properly without any decomposition during the experiments. They were rather stable both in aqueous media and solid state.
文摘Objective:To assess the acute and subacute toxicity as well as the phytochemical composition of two extracts and three fractions of Ammi majus L.Methods:The aqueous extracts were prepared separately by maceration for 48 h and by infusion for 1 h,while the fractions were prepared by the Soxhlet extractor,successively employing cyclohexane,ethyl acetate,and ethanol.The acute toxicity study was carried out in accordance with the OECD N°423 guideline at a single dose(2000 mg/kg)in mice for 14 days.The subacute toxicity study was performed by a daily oral administration of 250 mg/kg 2 for 10 d and 100 mg/kg doses for 28 d.Phytochemical screening was performed using staining and precipitation reactions,while the chemical characterization of some analytes was detected by HPLC-MS/MS analysis.Results:In the acute toxicity study,no signs of toxicity such as convulsion,salivation,diarrhea,sleep and coma were observed during 30 minutes and 14 days,so the lethal dose was higher than 2000 mg/kg for each extract and fraction.The subacute toxicity results showed that at a dose of 250 mg/kg,61.10%of the animals died and the rest developed morbidity.On the other hand,at a dose of 100 mg/kg,all the animals were still alive after 28 days,with no morbidity and the biochemical parameters were normal with no abnormalities in the liver,kidneys and pancreas.Phytochemical screening indicated the presence of flavonoids,tannins,coumarins,and free quinones and the absence of alkaloids and anthocyanins.Conclusions:The extracts and fractions of Ammi majus L.are not toxic in the short and long term with a varied chemical composition.Toxicological tests on animals other than rodents and in the long term(more than 28 days)are needed to further confirm the safety of Ammi majus extracts.
文摘The objective of this study is to determine the geochemical role of molluscs in the distribution of uranium in the marine ecosystem. Biogeochemical studies are carried out on recent mollusc shells from the Caspian Sea, Sea of Japan, Sea of Marmara, Aegean Sea, Black Sea, Mediterranean Sea, Baltic Sea, and Indian Ocean, which differ from each other in terms of physical, chemical, geographic, and geochemical characteristics. In this study, nine Gastropoda and fifty-four Pelecypoda shells of different species are analyzed to document variations of uranium in seasonal layers, which were formed by the seasonal carbonate-organic phase of molluscs during their entire lives. Shell used in this study principally comprises three layers: upper (outer) prismatic, middle prismatic, and inner (mother-of-pearl) layers. In addition, when possible, the head, the middle, and the lower parts of the shells are used for analyses separately. Also, the biological accumulation rate values for each different mollusc species rel
文摘In this study, Ultra High Performance Electrospray Ionization Ion Trap Time of Flight Mass Spectrometry （UHPLC-ESI-1T-TOF MS） method is used to screen the polymer additives in drinking water that is stored in Polyethylene Terephthalate （PET） bottles. After directly analyzing the commercially available water samples, 3 polymer additives （chimassorb 81, irgafos 168 and oleamide） were detected. However, after exposure to sunshine for 8 days, two additional polymer additives （antioxidant 2246 and Butylated Hydroxytoluene （BHT）） were detected besides the former three additives.
