According to practice and exploration of spark program for 26 years in Quanzhou,the main model and their effects of new rural construction in west bank of Taiwan Strait led by spark science and technology were expound...According to practice and exploration of spark program for 26 years in Quanzhou,the main model and their effects of new rural construction in west bank of Taiwan Strait led by spark science and technology were expounded. Six spark program systems were established,consisting of policy support guide,science and technology project lead,experts' intelligence support,spark science and technology training,scitech information service and spark program demonstration. Five spark projects were implemented to promote new rural construction in the west bank of Taiwan Strait,such as constructing the national spark industrial zone,organizing the new rural construction led by science and technology,constituting spark sci-tech innovation center,developing the rural informatization,and establishing science and technology commissioner bases. Finally,enlightenment of spark program and its development ways in the future were put forward.展开更多
The characteristics of diffusion are essential to the transport of radionuclides through buffer/backfill materials, such as bentonite, which are commonly found in waste repositories. This study used through-diffusion ...The characteristics of diffusion are essential to the transport of radionuclides through buffer/backfill materials, such as bentonite, which are commonly found in waste repositories. This study used through-diffusion techniques to investigate the diffusion behavior of HTO and ^(99)TcO_4^- on GMZ bentonite of various densities. Diffusion rates were calculated by measuring the diffusion coefficients(De, Da), plotting breakthrough curves and interpreting experiment data. The apparent and effective diffusion coefficients of HTO ranged from(1.68 ± 0.40) 9 × 10^(-11) to(2.80 ± 0.62) 9 × 10^(-11) m^2/s and from(4.61 ±1.28) 9 × 10^(-12) to (16.2 ± 2.50) 9 × 10^(-12) m^2/s, respectively.The apparent and effective diffusion coefficients of^(99)TcO_4^-ranged from(5.26 ± 0.16) 9 × 10^-12to(7.78 ± 0.43) 9× 10^-12m^2/s and from(1.49 ± 0.002) 9 × 10^(-12) to(4.16 ±0.07) 9 × 10^(-12) m^2/s, respectively. The distribution coefficients of HTO and^(99)TcO_4^-ranged from(0.70 ± 0.12) 9× 10^(-2) to(1.36 ± 0.53) 9 × 10^(-2) mL/g and from(1.12 ±0.06) 9 × 10^(-2) to(5.79 ± 2.22) 9 × 10^(-2) mL/g, respectively.The Deand Kdvalues were shown to decrease with an increase in the bulk dry density of compacted bentonite. Our results show that HTO and ^(99)Tc could be considered nonsorbent radionuclides. The data obtained in this studyprovide a valuable reference for the safety assessment of waste repositories.展开更多
Phosphors of BaLiF3 doped with Eu or/and Ce were solvothermally prepared at 200℃ for 5 d and characterized by means of X-ray powder diffraction （XRD） and environment scanning electron microscopy （ESEM）. The excit...Phosphors of BaLiF3 doped with Eu or/and Ce were solvothermally prepared at 200℃ for 5 d and characterized by means of X-ray powder diffraction （XRD） and environment scanning electron microscopy （ESEM）. The excitation and emission spectra of the rare earth ions doped BaLiF3 were measured by fluorescence spectroscopy and the effects of Ce3＋ ions on the luminescence of Eu〉 ions were in- vestigated. In the co-doped Eu2＋ and Ce3＋ system, the emission intensity of Eu2＋ ion gradually increased with the Ce3＋ concentration increas- ing, and the enhancement of Eu2＋ fluorescence was due to efficient energy transfer from Ce3＋ to Eu2＋ in the host.展开更多
Auxin signaling and its components(Auxin/Indole-3-Acetic Acid(Aux/IAA))are critical for plant growth and development.Here,we performed a genome-wide annotation and identified twenty-one Aux/IAA genes in strawberry(Fra...Auxin signaling and its components(Auxin/Indole-3-Acetic Acid(Aux/IAA))are critical for plant growth and development.Here,we performed a genome-wide annotation and identified twenty-one Aux/IAA genes in strawberry(Fragaria vesca).Most FveIAAs were located on chromosomes 1,2,4,5,and 6,while no FveIAAs were found in chromosomes 3 and 7.Phylogenetic analysis divided these genes into nine subfamilies.Most FveIAAs contained the DNA-binding and Aux/IAA domains,as well as motifs I-IV.There were 2-6 exons in the FveIAA genes based on the gene structure analysis.Also,we found that four pairs of FveIAA genes underwent segment duplications.Moreover,four pairs of orthologous genes were observed between strawberry and Arabidopsis.Cis-element analysis in the promoter region indicated that FveIAAs may be involved in light,phytohormones,stress responses,and growth processes.Prediction of protein-protein interaction revealed that 17 of 21 FveIAA proteins were involved in the auxin-related signaling pathways.Additionally,FveIAAs showed tissue-specific expression and responded to IAA treatment.Thus,this systematic annotation of the FveIAA family would provide a fundamental basis for further functional and evolutionary analysis and to understanding the role of FveIAAs in strawberry growth and development.展开更多
We report a compact and wavelength-tunable periodically poled lithium niobate(PPLN)Q-switched laser with intra-cavity optical parametric generation,producing 8-ns,10-𝜈μJ pulses at 10-kHz repetition rate when ...We report a compact and wavelength-tunable periodically poled lithium niobate(PPLN)Q-switched laser with intra-cavity optical parametric generation,producing 8-ns,10-𝜈μJ pulses at 10-kHz repetition rate when pumped with a 10-W diode laser at 808nm.The output wavelength can be tuned from 1450nm to 1600nm.Multiple-pulse generation was observed in the experiment.展开更多
The present study explores the effects of void-reactivity feedback and neutron interaction on the nonlinear phenomena of a seven-nuclear-coupled boiling channel system with a constant total flow rate. The results show...The present study explores the effects of void-reactivity feedback and neutron interaction on the nonlinear phenomena of a seven-nuclear-coupled boiling channel system with a constant total flow rate. The results show that the void-reactivity feedback and the neutron interaction both have significant effects on the nonlinear characteristics of this system. The complex nonlinear phenomena may depend on the magnitudes of the void-reactivity coefficient and neutron interaction parameter. The results demonstrate that complex nonlinear phenomena, i.e. various complex periodic oscillations and complex chaotic oscillations, can appear in the present system as the variations over certain values of void-reactivity coefficient and neutron interaction parameter under some specific operating states. These imply multiple complex periodic and chaotic attractors, with very interesting and peculiar shapes on the phase space, exist in this system.展开更多
Objective To establish a scientific,reliable,objective,and effective clinical comprehensive evaluation system for drugs centralized bidding procurement by government,and to conduct reliability and validity test and em...Objective To establish a scientific,reliable,objective,and effective clinical comprehensive evaluation system for drugs centralized bidding procurement by government,and to conduct reliability and validity test and empirical analysis of the evaluation index system through simulated measurement.Methods Literature research method was used to select comprehensive evaluation indicators for drugs centralized bidding procurement.Then,Dephi method was applied to screen the final evaluation indicators,and the weight of the indicators was determined using analytic hierarchy process.Results and Conclusion The final clinical efficacy evaluation index system for drugs centralized bidding procurement includes 5 primary indicators and 13 secondary indicators.The experts authority coefficient in this study is high,and their opinions relatively coincide.Through the empirical research,the reliability and structural validity of the indicator system is good.This indicator system enriches methods and tools for scientifically evaluating the clinical efficacy of drugs centralized bidding procurement.展开更多
Non-alcoholic fatty liver disease(NAFLD)has emerged as a global public health concern,affecting over one-quarter of the global population.It is closely associated with the prevalence of obesity and metabolic syndrome....Non-alcoholic fatty liver disease(NAFLD)has emerged as a global public health concern,affecting over one-quarter of the global population.It is closely associated with the prevalence of obesity and metabolic syndrome.Current treatment options for NAFLD are limited and often have side effects.Traditional Chinese medicine(TCM)offers a promising alternative with its holistic approach and use of multi-component herbal formulations.A recent study explored the potential of the TCM formula,"Fanlian Huazhuo Formula(FLHZF)",to alleviate high-fat dietinduced NAFLD by regulating autophagy and lipid synthesis signaling pathways.TCM has shown advantages in the prevention and treatment of NAFLD due to its efficacy and minimal side effects.However,the complex multicomponent and multitarget characteristics of formulas such as FLHZF present challenges in research.Future studies should focus on utilizing modern techniques to deepen our understanding of the mechanisms of action and active ingredients of Chinese herbal medicines,thereby promoting their modernization.展开更多
Adult Chrysoperla sinica Tjeder is a common pollen feeder in maize fields. They are thus directly exposed to insecticidal proteins by consumption of genetically engineered maize pollen containing Bacillus thuringiensi...Adult Chrysoperla sinica Tjeder is a common pollen feeder in maize fields. They are thus directly exposed to insecticidal proteins by consumption of genetically engineered maize pollen containing Bacillus thuringiensis(Bt) proteins. Here we assessed the potential effects of Cry1 Ab/2 Aj-or Cry1 Ac-containing Bt maize pollen on the fitness of adult C. sinica via a dietary-exposure assay under laboratory conditions. Survival, pre-oviposition, fecundity and adult dry weight did not differ between adult C. sinica consuming Bt or the corresponding non-Bt maize pollen. The stability of the Cry protein in the food sources and uptake of the Cry protein by adult C. sinica during the feeding experiment were confirmed by ELISA. These results demonstrate that adult C. sinica are not affected by the consumption of Cry1 Ab/2 Aj-or Cry1 Ac-containing maize pollen, suggesting that production of Bt maize expressing cry1 Ab/2 Aj or cry1 Ac genes will pose a negligible risk to adult C. sinica.展开更多
Objective: The objective of this work is to search for a novel method to explore the disrupted pathways associated with periodontitis(PD) based on the network level.Methods: Firstly, the differential expression genes(...Objective: The objective of this work is to search for a novel method to explore the disrupted pathways associated with periodontitis(PD) based on the network level.Methods: Firstly, the differential expression genes(DEGs) between PD patients and cognitively normal subjects were inferred based on LIMMA package. Then, the proteinprotein interactions(PPI) in each pathway were explored by Empirical Bayesian(EB) coexpression program. Specifically, we determined the 100 th weight value as the threshold value of the disrupted pathways of PPI by constructing the randomly model and confirmed the weight value of each pathway. Meanwhile, we dissected the disrupted pathways under the weight value > the threshold value. Pathways enrichment analyses of DEGs were carried out based on Expression Analysis Systematic Explored(EASE) test. Finally, the better method was selected based on the more rich and significant obtained pathways by comparing the two methods. Results: After the calculation of LIMMA package, we estimated 524 DEGs in all. Then we determined 0.115222 as the threshold value of the disrupted pathways of PPI. When the weight value>0.115222, there were 258 disrupted pathways of PPI enriched in. Additionally, we observed those 524 DEGs that were enriched in 4 pathways under EASE=0.1.Conclusion: We proposed a novel network method inferring the disrupted pathway for PD. The disrupted pathways might be underlying biomarkers for treatment associated with PD.展开更多
头颈部(head and neck,HN)癌是台湾地区的一种地方性疾病。全量照射后局部复发的HN癌是一个治疗挑战,而硼中子俘获疗法(boron neutron capture therapy,BNCT)是一种能够提供持久局部控制且毒性可耐受的解决方案。位于新竹清华大学的清...头颈部(head and neck,HN)癌是台湾地区的一种地方性疾病。全量照射后局部复发的HN癌是一个治疗挑战,而硼中子俘获疗法(boron neutron capture therapy,BNCT)是一种能够提供持久局部控制且毒性可耐受的解决方案。位于新竹清华大学的清华开放池反应堆(Tsing-Hua Open Pool Reactor,THOR)为基础和临床BNCT研究提供了一个高质量的超热中子源。我们于2010年至2013年间开展了名为"在THOR应用硼中子俘获疗法治疗复发性头颈癌的I/II期临床试验"的首项临床试验。17例患者被招募至该研究,共有23个复发性HN肿瘤接受了高剂量光子照射。以L-硼苯丙氨酸的果糖复合物为硼载体,每例患者进行了间隔28天的2次分割BNCT治疗。结果其毒性可以耐受,虽然反应率高(12/17),但常见放射部位或附近区再次复发。为了获得更好的局部控制,2014年启动了另一项临床试验,名为"硼中子俘获疗法联合影像引导的调强放疗(image-guided intensity-modulated radiotherapy,IG-IMRT)治疗局部复发性HN癌的I/II期临床试验"。按照我们之前的方案首先进行BNCT,在BNCT后28天开始进行IG-IMRT。截至2017年5月,已有7例患者接受了这种联合治疗。治疗相关毒性与之前两次使用BNCT时观察到的毒性相似。3例患者实现完全缓解,但尽管初期反应良好,局部复发仍是治疗失败的主要原因。未来将在THOR开展局部或全身治疗与BNCT联合应用来治疗复发性HN癌患者的其他临床试验。展开更多
Objective:To investigate the differences between meditation and resting states using infrared thermal imaging(IRTI)to determine facial temperature distribution features during meditation and annotate the patterns of f...Objective:To investigate the differences between meditation and resting states using infrared thermal imaging(IRTI)to determine facial temperature distribution features during meditation and annotate the patterns of facial temperature changes during meditation from the perspective of traditional Chinese medicine facial diagnosis.Methods:Each participant performed 10 min meditation and 10 min resting but in different sequences.A concentration test was set as the task load,followed by a meditation/resting or resting/meditation session,during which the participants'facial temperatures were observed using IRTI.Participants were scored on the Big Five Inventory(BFI)and Mindful Attention Awareness Scale(MAAS).Results:Forehead temperatures decreased more during meditation than during the resting state.The chin temperature increased only during meditation(P<.0001).For the subjects with meditation experience,there were significant differences in the temperatures of the left forehead(P<.01),right forehead(P<.01)and chin(P<.05)between the meditation and resting state at the 10~(th)min.In the nontask state,the BFI-Extraversion showed a negative correlation with the temperature of the left forehead(R=-0.41,P=.03).In the post-task state,the temperature of the left forehead was negatively correlated with scores on the MAAS(R=-0.42,P=.02).Conclusion:Using IRTI to study meditation offers a practical solution to the challenges in meditation research.The results indicate that an increase in chin temperature may be a representative feature of a meditation state,and forehead temperature is also a potential indicator.展开更多
With the gradual increase of car ownership in China and the continuous expansion of travel radius,traffic accidents caused by car safety are also increasing.As far as automobile safety itself is concerned,its evaluati...With the gradual increase of car ownership in China and the continuous expansion of travel radius,traffic accidents caused by car safety are also increasing.As far as automobile safety itself is concerned,its evaluation method is constantly evolving,but the safety of automobile textiles,which is an important part of it,is still in its infancy.The article starts from the factors that affect the safety performance of automobiles such as automobile safety theory,vehicle ergonomics and automobile textile performance.Then,the methods of expert investigation,analytic hierarchy process,fuzzy comprehensive evaluation and data analysis are used.In this way,we obtain a grade set for a multi-level index system and determine the weight of each index.Finally,we establish a comprehensive evaluation system for safety of the automobile textiles and select parameters under extreme conditions to verify the system,which proves to be effective and feasible.展开更多
Biochar is widely used to improve soil physical properties and carbon sequestration. However, few studies focuse on the impact of maize stalk biochar on labile organic carbon(LOC) pool and the relationship between phy...Biochar is widely used to improve soil physical properties and carbon sequestration. However, few studies focuse on the impact of maize stalk biochar on labile organic carbon(LOC) pool and the relationship between physical properties and LOC fractions. A field positioning experiment was performed in Mollisols region of Northeast China to evaluate the influence of maize stalk biochar on the spatial distribution and temporal changes of physical properties and LOC fractions. Maize stalk biochar treatments included C1(1.5 kg·hm^(-2)), C2(3 kg·hm^(-2)), C3(15 kg·hm^(-2)), C4(30 kg·hm^(-2)), and CK(0). The results showed that maize stalk biochar increased soil water contents(SWC) and soil porosity(SP), but reduced bulk density(BD). Maize stalk biochar reduced dissolved organic carbon(DOC) contents in the 0-20 cm soil layer, ranging from 0.25 g·kg^(-1) to 0.31 g·kg^(-1) in harvest period, while increased in the 20-40 cm soil layer. In addition, the application of biochar had a significant impact on the spatial distribution and temporal change of SWC, BD, SP, DOC, hot-water extractable carbon(HWC), acid hydrolyzed organic carbon(AHC Ⅰ, Ⅱ), and readily oxidized organic carbon(ROC). High amounts of maize stalk biochar up-regulated the contents of soil organic carbon SOC, HWC, AHC Ⅰ, AHC Ⅱ, and ROC. In addition, SWC and SP were the key physical factors to affect LOC fractions. In conclusions, maize stalk biochar could improve physical properties, and then influence LOC fractions, and maize stalk biochar could be used as an organic amendment for restoring degraded soils governed by their rates of addition.展开更多
With Camellia sinensis( L.) O. Kuntze cv Fuding Dabaicha as the control,an experiment was conducted to study the adaptability of Yunnan tea cultivars Zijuan,Yunkang 10,Yunkang 14,Foxiang 3,Yuncha 1,Jinggu Dabaicha,Xue...With Camellia sinensis( L.) O. Kuntze cv Fuding Dabaicha as the control,an experiment was conducted to study the adaptability of Yunnan tea cultivars Zijuan,Yunkang 10,Yunkang 14,Foxiang 3,Yuncha 1,Jinggu Dabaicha,Xueya 100,in Zhangzhou,south Fujian tea area,during 2012- 2014. The results show that the tea cultivars( Yunkang 14,Foxiang 3,Jinggu Dabaicha) grow in general conditions;while the cultivars( Zijuan,Yunkang 10,Yuncha 1,Xueya 100) show good adaptability in south Fujian tea area,and they grow in good conditions,and they are as good as the control cultivar Fuding Dabaicha,in terms of bud leaf traits,resistance and chemical quality,etc. So these cultivars are suitable for cultivation in southern Fujian tea area.展开更多
The improved physical information neural network algorithm has been proven to be used to study integrable systems. In this paper, the improved physical information neural network algorithm is used to study the defocus...The improved physical information neural network algorithm has been proven to be used to study integrable systems. In this paper, the improved physical information neural network algorithm is used to study the defocusing nonlinear Schrödinger (NLS) equation with time-varying potential, and the rogue wave solution of the equation is obtained. At the same time, the influence of the number of network layers, neurons and the number of sampling points on the network performance is studied. Experiments show that the number of hidden layers and the number of neurons in each hidden layer affect the relative L<sub>2</sub>-norm error. With fixed configuration points, the relative norm error does not decrease with the increase in the number of boundary data points, which indicates that in this case, the number of boundary data points has no obvious influence on the error. Through the experiment, the rogue wave solution of the defocusing NLS equation is successfully captured by IPINN method for the first time. The experimental results of this paper are also compared with the results obtained by the physical information neural network method and show that the improved algorithm has higher accuracy. The results of this paper will be contributed to the generalization of deep learning algorithms for solving defocusing NLS equations with time-varying potential.展开更多
Objective:The objective of the study was to investigate the situation of depression/anxiety in patients with coronary heart disease(CHD)at different stages of the disease and to analyze the influencing factors and the...Objective:The objective of the study was to investigate the situation of depression/anxiety in patients with coronary heart disease(CHD)at different stages of the disease and to analyze the influencing factors and the evolution characteristics of traditional Chinese medicine(TCM)syndromes.Materials and Methods:From October 2016 to April 2018,a cross-sectional survey was conducted at 48 clinical research centers in 23 provinces,cities,and autonomous regions across China.A total of 11383 cases were collected by outpatient or inpatient cases,including healthy individuals(n=1754),low-risk individuals(n=2339),metabolic syndrome(n=1475),stable CHD(n=3366),acute coronary syndrome(n=704),perioperative intervention treatment(n=753),and heart failure(n=992).Survey demographic data,lifestyle habits,disease and health status,TCM symptoms and signs,and other information were collected.Results:The prevalence rates of depression/anxiety in surveyed patients with CHD were 35.7%and 21.0%,respectively,and were higher than those in patients with metabolic syndrome(18.8%and 10.3%,respectively),low-risk individuals(11.7%and 7.5%),and healthy individuals(9.7%and 5.7%,respectively).The significant risk factors for CHD combined with depression analyzed by the generalized linear mixed model included age(odds ratio[OR]=0.019),gender(OR=0.632),hypertension(OR=0.306),course of CHD(OR=0.022),stent placement(OR=-0.284),heart function level(OR=-4.151/-3.336/-2.118),and phlegm stasis syndrome score(OR=0.129).The significant risk factors for CHD combined with anxiety included gender(OR=0.581),heart function level(OR=-1.856),and phlegm stasis syndrome score(OR=0.094).Factor analysis was conducted on the symptoms and signs of patients with CHD combined with depression/anxiety,and 16 common factors were obtained with cumulative contribution rates of 62.83%and 66.13%,respectively.Disease syndromes included liver and kidney deficiency syndrome,liver stagnation and discomfort syndrome,Qi deficiency syndrome,liver meridian fire heat syndrome,kidney deficiency syndrome,phlegm dampness syndrome,heart and gallbladder Qi deficiency syndrome,blood stasis syndrome,lung Qi inversion syndrome,Yang deficiency syndrome,and three symptoms named diseases,including chest tightness,chest pain,insomnia,and head discomfort.Conclusions:Through cross-sectional design,the data obtained in this study revealed the actual situation of CHD patients with anxiety or depression at different stages.The influencing factors of CHD patients with depression or anxiety were analyzed through the collected cross-sectional information and further revealed the syndromic characteristics of CHD patients with depression or anxiety at different stages from the perspective of TCM syndromes.The data obtained provide a practical basis for further understanding the clinical characteristics of bicardiac diseases and for proposing treatment strategies in stages.展开更多
The mismatch between the actual heat production of an air source heat pump (ASHP) and the instantaneous load of the building it heats is a critical cause of low energy efficiency. Research on the measured heating effe...The mismatch between the actual heat production of an air source heat pump (ASHP) and the instantaneous load of the building it heats is a critical cause of low energy efficiency. Research on the measured heating effect provides an effective approach to improve the energy efficiency of an ASHP. This study therefore focused on two small office buildings to explore the operating data describing the ASHP system source and load sides during the heating season. A sensitivity analysis was employed to explore the actual operational effects of the ASHP. Common problems associated with system operation were comprehensively identified, including the operation characteristics, energy efficiency coefficients, load characteristics, and energy consumption characteristics of the transmission and distribution systems. The effects of these problems were evaluated from three perspectives: integrated part load value (IPLV), system performance loss, and indoor environmental parameters. The results shows that the highest coefficient of performance (COP) of the ASHP in Building A was 3.27 while the IPLV was 2.68, operating status reached the standard. The COP value of the ASHP in Building B was 1.55 while the IPLV was 2.45. Poor value shows the low performance in operating phase, which can be further optimised by matching the building instantaneous load to the heat production of the ASHP, improves the operating effect of two buildings comprehensively.展开更多
Head and neck(HN)cancer is an endemic disease in Taiwan,China.Locally recurrent HN cancer after full-dose irradia-tion poses a therapeutic challenge,and boron neutron capture therapy(BNCT)may be a solution that could ...Head and neck(HN)cancer is an endemic disease in Taiwan,China.Locally recurrent HN cancer after full-dose irradia-tion poses a therapeutic challenge,and boron neutron capture therapy(BNCT)may be a solution that could provide durable local control with tolerable toxicity.The Tsing-Hua Open Pool Reactor(THOR)at National Tsing-Hua University in Hsin-Chu,provides a high-quality epithermal neutron source for basic and clinical BNCT research.Our first clinical trial,entitled“A phase I/II trial of boron neutron capture therapy for recurrent head and neck cancer at THOR”,was carried out between 2010 and 2013.A total of 17 patients with 23 recurrent HN tumors who had received high-dose photon irradiation were enrolled in the study.The fructose complex of l-boronophenylalanine was used as a boron carrier,and a two-fraction BNCT treatment regimen at 28-day intervals was used for each patient.Toxicity was acceptable,and although the response rate was high(12/17),re-recurrence within or near the radiation site was common.To obtain better local control,another clinical trial entitled“A phase I/II trial of boron neutron capture therapy combined with image-guided intensity-modulated radiotherapy(IG-IMRT)for locally recurrent HN cancer”was initiated in 2014.The first administration of BNCT was performed according to our previous protocol,and IG-IMRT was initiated 28 days after BNCT.As of May 2017,seven patients have been treated with this combination.The treatment-related toxicity was similar to that previously observed with two BNCT applications.Three patients had a complete response,but locoregional recurrence was the major cause of failure despite initially good responses.Future clinical trials combining BNCT with other local or systemic treatments will be carried out for recurrent HN cancer patients at THOR.展开更多
Aiming at the complex and restrictive characteristics of human resource allocation in multiple scientific university research projects, an improved pigeon-inspired optimization(IPIO) algorithm is proposed wherein loss...Aiming at the complex and restrictive characteristics of human resource allocation in multiple scientific university research projects, an improved pigeon-inspired optimization(IPIO) algorithm is proposed wherein loss minimization and the shortest project delay time are considered as optimization goals. Firstly, mathematical modelling of the problem is carried out, and the multi-objective optimization problem is transformed into a single-objective optimization problem by means of a weighted solution. In the second step, the traditional pigeon-inspired optimization(PIO) algorithm is discretized, and an adaptive parameter strategy is adopted to improve the shortcomings of the algorithm itself. Finally, by comparing the simulation results with the original algorithm and the genetic algorithm in the optimization of human resource allocation in multiple projects, the feasibility and superiority of the proposed algorithm in the optimization of human resource allocation in multi-scientific research projects is verified.展开更多
基金Supported by the Regional Science and Technology Project of Fujian Province,China(2009N3007)Science and Technology Project of Quanzhou City,Fujian Province,China(2008ZD11-1)12396 Multimedia Information Remote Service Platform Construction of Spark Science and Technology for Quanzhou City,Fujian Province,China(2008ZD15,2011ZD04N01)
文摘According to practice and exploration of spark program for 26 years in Quanzhou,the main model and their effects of new rural construction in west bank of Taiwan Strait led by spark science and technology were expounded. Six spark program systems were established,consisting of policy support guide,science and technology project lead,experts' intelligence support,spark science and technology training,scitech information service and spark program demonstration. Five spark projects were implemented to promote new rural construction in the west bank of Taiwan Strait,such as constructing the national spark industrial zone,organizing the new rural construction led by science and technology,constituting spark sci-tech innovation center,developing the rural informatization,and establishing science and technology commissioner bases. Finally,enlightenment of spark program and its development ways in the future were put forward.
基金the Nuclear Backend Management Department at Taiwan Power Company for financially supporting this research
文摘The characteristics of diffusion are essential to the transport of radionuclides through buffer/backfill materials, such as bentonite, which are commonly found in waste repositories. This study used through-diffusion techniques to investigate the diffusion behavior of HTO and ^(99)TcO_4^- on GMZ bentonite of various densities. Diffusion rates were calculated by measuring the diffusion coefficients(De, Da), plotting breakthrough curves and interpreting experiment data. The apparent and effective diffusion coefficients of HTO ranged from(1.68 ± 0.40) 9 × 10^(-11) to(2.80 ± 0.62) 9 × 10^(-11) m^2/s and from(4.61 ±1.28) 9 × 10^(-12) to (16.2 ± 2.50) 9 × 10^(-12) m^2/s, respectively.The apparent and effective diffusion coefficients of^(99)TcO_4^-ranged from(5.26 ± 0.16) 9 × 10^-12to(7.78 ± 0.43) 9× 10^-12m^2/s and from(1.49 ± 0.002) 9 × 10^(-12) to(4.16 ±0.07) 9 × 10^(-12) m^2/s, respectively. The distribution coefficients of HTO and^(99)TcO_4^-ranged from(0.70 ± 0.12) 9× 10^(-2) to(1.36 ± 0.53) 9 × 10^(-2) mL/g and from(1.12 ±0.06) 9 × 10^(-2) to(5.79 ± 2.22) 9 × 10^(-2) mL/g, respectively.The Deand Kdvalues were shown to decrease with an increase in the bulk dry density of compacted bentonite. Our results show that HTO and ^(99)Tc could be considered nonsorbent radionuclides. The data obtained in this studyprovide a valuable reference for the safety assessment of waste repositories.
基金Project supported by National Natural Science Foundation of China (U0734005, 20906037)the Fundamental Research Funds for the Central Universities (21610102)the Doctor Special Foundation of Zhanjiang Normal University (ZL1104)
文摘Phosphors of BaLiF3 doped with Eu or/and Ce were solvothermally prepared at 200℃ for 5 d and characterized by means of X-ray powder diffraction （XRD） and environment scanning electron microscopy （ESEM）. The excitation and emission spectra of the rare earth ions doped BaLiF3 were measured by fluorescence spectroscopy and the effects of Ce3＋ ions on the luminescence of Eu〉 ions were in- vestigated. In the co-doped Eu2＋ and Ce3＋ system, the emission intensity of Eu2＋ ion gradually increased with the Ce3＋ concentration increas- ing, and the enhancement of Eu2＋ fluorescence was due to efficient energy transfer from Ce3＋ to Eu2＋ in the host.
基金supported by the Natural Science Foundation of China(31701935)the Agricultural technology R&D Project of Xi’an City(20NYYF0037)+2 种基金the Natural Science Foundation of Chongqing(cstc2020jcyjmsxmX1064)We also gratefully thank funding from the Plant Biotechnology and Germplasm Conservation Project(XAWLKYTD017)Key Disciplines of Botany of Xi’an City(103060002).
文摘Auxin signaling and its components(Auxin/Indole-3-Acetic Acid(Aux/IAA))are critical for plant growth and development.Here,we performed a genome-wide annotation and identified twenty-one Aux/IAA genes in strawberry(Fragaria vesca).Most FveIAAs were located on chromosomes 1,2,4,5,and 6,while no FveIAAs were found in chromosomes 3 and 7.Phylogenetic analysis divided these genes into nine subfamilies.Most FveIAAs contained the DNA-binding and Aux/IAA domains,as well as motifs I-IV.There were 2-6 exons in the FveIAA genes based on the gene structure analysis.Also,we found that four pairs of FveIAA genes underwent segment duplications.Moreover,four pairs of orthologous genes were observed between strawberry and Arabidopsis.Cis-element analysis in the promoter region indicated that FveIAAs may be involved in light,phytohormones,stress responses,and growth processes.Prediction of protein-protein interaction revealed that 17 of 21 FveIAA proteins were involved in the auxin-related signaling pathways.Additionally,FveIAAs showed tissue-specific expression and responded to IAA treatment.Thus,this systematic annotation of the FveIAA family would provide a fundamental basis for further functional and evolutionary analysis and to understanding the role of FveIAAs in strawberry growth and development.
基金Supported by the National Science Council,Taiwan,China under contract NSC97-2221-E-007-029.
文摘We report a compact and wavelength-tunable periodically poled lithium niobate(PPLN)Q-switched laser with intra-cavity optical parametric generation,producing 8-ns,10-𝜈μJ pulses at 10-kHz repetition rate when pumped with a 10-W diode laser at 808nm.The output wavelength can be tuned from 1450nm to 1600nm.Multiple-pulse generation was observed in the experiment.
文摘The present study explores the effects of void-reactivity feedback and neutron interaction on the nonlinear phenomena of a seven-nuclear-coupled boiling channel system with a constant total flow rate. The results show that the void-reactivity feedback and the neutron interaction both have significant effects on the nonlinear characteristics of this system. The complex nonlinear phenomena may depend on the magnitudes of the void-reactivity coefficient and neutron interaction parameter. The results demonstrate that complex nonlinear phenomena, i.e. various complex periodic oscillations and complex chaotic oscillations, can appear in the present system as the variations over certain values of void-reactivity coefficient and neutron interaction parameter under some specific operating states. These imply multiple complex periodic and chaotic attractors, with very interesting and peculiar shapes on the phase space, exist in this system.
文摘Objective To establish a scientific,reliable,objective,and effective clinical comprehensive evaluation system for drugs centralized bidding procurement by government,and to conduct reliability and validity test and empirical analysis of the evaluation index system through simulated measurement.Methods Literature research method was used to select comprehensive evaluation indicators for drugs centralized bidding procurement.Then,Dephi method was applied to screen the final evaluation indicators,and the weight of the indicators was determined using analytic hierarchy process.Results and Conclusion The final clinical efficacy evaluation index system for drugs centralized bidding procurement includes 5 primary indicators and 13 secondary indicators.The experts authority coefficient in this study is high,and their opinions relatively coincide.Through the empirical research,the reliability and structural validity of the indicator system is good.This indicator system enriches methods and tools for scientifically evaluating the clinical efficacy of drugs centralized bidding procurement.
文摘Non-alcoholic fatty liver disease(NAFLD)has emerged as a global public health concern,affecting over one-quarter of the global population.It is closely associated with the prevalence of obesity and metabolic syndrome.Current treatment options for NAFLD are limited and often have side effects.Traditional Chinese medicine(TCM)offers a promising alternative with its holistic approach and use of multi-component herbal formulations.A recent study explored the potential of the TCM formula,"Fanlian Huazhuo Formula(FLHZF)",to alleviate high-fat dietinduced NAFLD by regulating autophagy and lipid synthesis signaling pathways.TCM has shown advantages in the prevention and treatment of NAFLD due to its efficacy and minimal side effects.However,the complex multicomponent and multitarget characteristics of formulas such as FLHZF present challenges in research.Future studies should focus on utilizing modern techniques to deepen our understanding of the mechanisms of action and active ingredients of Chinese herbal medicines,thereby promoting their modernization.
基金supported by the National GMO New Variety Breeding Program of China(2015ZX08013-003)
文摘Adult Chrysoperla sinica Tjeder is a common pollen feeder in maize fields. They are thus directly exposed to insecticidal proteins by consumption of genetically engineered maize pollen containing Bacillus thuringiensis(Bt) proteins. Here we assessed the potential effects of Cry1 Ab/2 Aj-or Cry1 Ac-containing Bt maize pollen on the fitness of adult C. sinica via a dietary-exposure assay under laboratory conditions. Survival, pre-oviposition, fecundity and adult dry weight did not differ between adult C. sinica consuming Bt or the corresponding non-Bt maize pollen. The stability of the Cry protein in the food sources and uptake of the Cry protein by adult C. sinica during the feeding experiment were confirmed by ELISA. These results demonstrate that adult C. sinica are not affected by the consumption of Cry1 Ab/2 Aj-or Cry1 Ac-containing maize pollen, suggesting that production of Bt maize expressing cry1 Ab/2 Aj or cry1 Ac genes will pose a negligible risk to adult C. sinica.
文摘Objective: The objective of this work is to search for a novel method to explore the disrupted pathways associated with periodontitis(PD) based on the network level.Methods: Firstly, the differential expression genes(DEGs) between PD patients and cognitively normal subjects were inferred based on LIMMA package. Then, the proteinprotein interactions(PPI) in each pathway were explored by Empirical Bayesian(EB) coexpression program. Specifically, we determined the 100 th weight value as the threshold value of the disrupted pathways of PPI by constructing the randomly model and confirmed the weight value of each pathway. Meanwhile, we dissected the disrupted pathways under the weight value > the threshold value. Pathways enrichment analyses of DEGs were carried out based on Expression Analysis Systematic Explored(EASE) test. Finally, the better method was selected based on the more rich and significant obtained pathways by comparing the two methods. Results: After the calculation of LIMMA package, we estimated 524 DEGs in all. Then we determined 0.115222 as the threshold value of the disrupted pathways of PPI. When the weight value>0.115222, there were 258 disrupted pathways of PPI enriched in. Additionally, we observed those 524 DEGs that were enriched in 4 pathways under EASE=0.1.Conclusion: We proposed a novel network method inferring the disrupted pathway for PD. The disrupted pathways might be underlying biomarkers for treatment associated with PD.
文摘头颈部(head and neck,HN)癌是台湾地区的一种地方性疾病。全量照射后局部复发的HN癌是一个治疗挑战,而硼中子俘获疗法(boron neutron capture therapy,BNCT)是一种能够提供持久局部控制且毒性可耐受的解决方案。位于新竹清华大学的清华开放池反应堆(Tsing-Hua Open Pool Reactor,THOR)为基础和临床BNCT研究提供了一个高质量的超热中子源。我们于2010年至2013年间开展了名为"在THOR应用硼中子俘获疗法治疗复发性头颈癌的I/II期临床试验"的首项临床试验。17例患者被招募至该研究,共有23个复发性HN肿瘤接受了高剂量光子照射。以L-硼苯丙氨酸的果糖复合物为硼载体,每例患者进行了间隔28天的2次分割BNCT治疗。结果其毒性可以耐受,虽然反应率高(12/17),但常见放射部位或附近区再次复发。为了获得更好的局部控制,2014年启动了另一项临床试验,名为"硼中子俘获疗法联合影像引导的调强放疗(image-guided intensity-modulated radiotherapy,IG-IMRT)治疗局部复发性HN癌的I/II期临床试验"。按照我们之前的方案首先进行BNCT,在BNCT后28天开始进行IG-IMRT。截至2017年5月,已有7例患者接受了这种联合治疗。治疗相关毒性与之前两次使用BNCT时观察到的毒性相似。3例患者实现完全缓解,但尽管初期反应良好,局部复发仍是治疗失败的主要原因。未来将在THOR开展局部或全身治疗与BNCT联合应用来治疗复发性HN癌患者的其他临床试验。
基金supported by the Fundamental Research Funds for the Central Universities(x2021-JYB-XJSJJ-032)Beijing Municipal Commission of Education,Double First-class,High-caliber Talents Grant(1000041510156)。
文摘Objective:To investigate the differences between meditation and resting states using infrared thermal imaging(IRTI)to determine facial temperature distribution features during meditation and annotate the patterns of facial temperature changes during meditation from the perspective of traditional Chinese medicine facial diagnosis.Methods:Each participant performed 10 min meditation and 10 min resting but in different sequences.A concentration test was set as the task load,followed by a meditation/resting or resting/meditation session,during which the participants'facial temperatures were observed using IRTI.Participants were scored on the Big Five Inventory(BFI)and Mindful Attention Awareness Scale(MAAS).Results:Forehead temperatures decreased more during meditation than during the resting state.The chin temperature increased only during meditation(P<.0001).For the subjects with meditation experience,there were significant differences in the temperatures of the left forehead(P<.01),right forehead(P<.01)and chin(P<.05)between the meditation and resting state at the 10~(th)min.In the nontask state,the BFI-Extraversion showed a negative correlation with the temperature of the left forehead(R=-0.41,P=.03).In the post-task state,the temperature of the left forehead was negatively correlated with scores on the MAAS(R=-0.42,P=.02).Conclusion:Using IRTI to study meditation offers a practical solution to the challenges in meditation research.The results indicate that an increase in chin temperature may be a representative feature of a meditation state,and forehead temperature is also a potential indicator.
基金National Natural Science Foundation of China(No.11804049)Fundamental Research Funds for the Central Universities,China(No.2232020G-01)+1 种基金Fundamental Research Funds for the Central Universities,China(No.2232019D3-14)Shanghai Technical Standards Projects,China(No.18DZ2205900)。
文摘With the gradual increase of car ownership in China and the continuous expansion of travel radius,traffic accidents caused by car safety are also increasing.As far as automobile safety itself is concerned,its evaluation method is constantly evolving,but the safety of automobile textiles,which is an important part of it,is still in its infancy.The article starts from the factors that affect the safety performance of automobiles such as automobile safety theory,vehicle ergonomics and automobile textile performance.Then,the methods of expert investigation,analytic hierarchy process,fuzzy comprehensive evaluation and data analysis are used.In this way,we obtain a grade set for a multi-level index system and determine the weight of each index.Finally,we establish a comprehensive evaluation system for safety of the automobile textiles and select parameters under extreme conditions to verify the system,which proves to be effective and feasible.
基金Supported by the National Natural Science Foundation of China Project(31770582)。
文摘Biochar is widely used to improve soil physical properties and carbon sequestration. However, few studies focuse on the impact of maize stalk biochar on labile organic carbon(LOC) pool and the relationship between physical properties and LOC fractions. A field positioning experiment was performed in Mollisols region of Northeast China to evaluate the influence of maize stalk biochar on the spatial distribution and temporal changes of physical properties and LOC fractions. Maize stalk biochar treatments included C1(1.5 kg·hm^(-2)), C2(3 kg·hm^(-2)), C3(15 kg·hm^(-2)), C4(30 kg·hm^(-2)), and CK(0). The results showed that maize stalk biochar increased soil water contents(SWC) and soil porosity(SP), but reduced bulk density(BD). Maize stalk biochar reduced dissolved organic carbon(DOC) contents in the 0-20 cm soil layer, ranging from 0.25 g·kg^(-1) to 0.31 g·kg^(-1) in harvest period, while increased in the 20-40 cm soil layer. In addition, the application of biochar had a significant impact on the spatial distribution and temporal change of SWC, BD, SP, DOC, hot-water extractable carbon(HWC), acid hydrolyzed organic carbon(AHC Ⅰ, Ⅱ), and readily oxidized organic carbon(ROC). High amounts of maize stalk biochar up-regulated the contents of soil organic carbon SOC, HWC, AHC Ⅰ, AHC Ⅱ, and ROC. In addition, SWC and SP were the key physical factors to affect LOC fractions. In conclusions, maize stalk biochar could improve physical properties, and then influence LOC fractions, and maize stalk biochar could be used as an organic amendment for restoring degraded soils governed by their rates of addition.
基金Supported by Youth Project of Fujian Provincial Department of Education(JA15908)
文摘With Camellia sinensis( L.) O. Kuntze cv Fuding Dabaicha as the control,an experiment was conducted to study the adaptability of Yunnan tea cultivars Zijuan,Yunkang 10,Yunkang 14,Foxiang 3,Yuncha 1,Jinggu Dabaicha,Xueya 100,in Zhangzhou,south Fujian tea area,during 2012- 2014. The results show that the tea cultivars( Yunkang 14,Foxiang 3,Jinggu Dabaicha) grow in general conditions;while the cultivars( Zijuan,Yunkang 10,Yuncha 1,Xueya 100) show good adaptability in south Fujian tea area,and they grow in good conditions,and they are as good as the control cultivar Fuding Dabaicha,in terms of bud leaf traits,resistance and chemical quality,etc. So these cultivars are suitable for cultivation in southern Fujian tea area.
文摘The improved physical information neural network algorithm has been proven to be used to study integrable systems. In this paper, the improved physical information neural network algorithm is used to study the defocusing nonlinear Schrödinger (NLS) equation with time-varying potential, and the rogue wave solution of the equation is obtained. At the same time, the influence of the number of network layers, neurons and the number of sampling points on the network performance is studied. Experiments show that the number of hidden layers and the number of neurons in each hidden layer affect the relative L<sub>2</sub>-norm error. With fixed configuration points, the relative norm error does not decrease with the increase in the number of boundary data points, which indicates that in this case, the number of boundary data points has no obvious influence on the error. Through the experiment, the rogue wave solution of the defocusing NLS equation is successfully captured by IPINN method for the first time. The experimental results of this paper are also compared with the results obtained by the physical information neural network method and show that the improved algorithm has higher accuracy. The results of this paper will be contributed to the generalization of deep learning algorithms for solving defocusing NLS equations with time-varying potential.
基金supported by funds from the National Key Basic Research and Development Program(“973”Program)(2014CB542903)National Key Research and Development Plan(2019YFC1708501)National Nature Science Foundation(81673845)。
文摘Objective:The objective of the study was to investigate the situation of depression/anxiety in patients with coronary heart disease(CHD)at different stages of the disease and to analyze the influencing factors and the evolution characteristics of traditional Chinese medicine(TCM)syndromes.Materials and Methods:From October 2016 to April 2018,a cross-sectional survey was conducted at 48 clinical research centers in 23 provinces,cities,and autonomous regions across China.A total of 11383 cases were collected by outpatient or inpatient cases,including healthy individuals(n=1754),low-risk individuals(n=2339),metabolic syndrome(n=1475),stable CHD(n=3366),acute coronary syndrome(n=704),perioperative intervention treatment(n=753),and heart failure(n=992).Survey demographic data,lifestyle habits,disease and health status,TCM symptoms and signs,and other information were collected.Results:The prevalence rates of depression/anxiety in surveyed patients with CHD were 35.7%and 21.0%,respectively,and were higher than those in patients with metabolic syndrome(18.8%and 10.3%,respectively),low-risk individuals(11.7%and 7.5%),and healthy individuals(9.7%and 5.7%,respectively).The significant risk factors for CHD combined with depression analyzed by the generalized linear mixed model included age(odds ratio[OR]=0.019),gender(OR=0.632),hypertension(OR=0.306),course of CHD(OR=0.022),stent placement(OR=-0.284),heart function level(OR=-4.151/-3.336/-2.118),and phlegm stasis syndrome score(OR=0.129).The significant risk factors for CHD combined with anxiety included gender(OR=0.581),heart function level(OR=-1.856),and phlegm stasis syndrome score(OR=0.094).Factor analysis was conducted on the symptoms and signs of patients with CHD combined with depression/anxiety,and 16 common factors were obtained with cumulative contribution rates of 62.83%and 66.13%,respectively.Disease syndromes included liver and kidney deficiency syndrome,liver stagnation and discomfort syndrome,Qi deficiency syndrome,liver meridian fire heat syndrome,kidney deficiency syndrome,phlegm dampness syndrome,heart and gallbladder Qi deficiency syndrome,blood stasis syndrome,lung Qi inversion syndrome,Yang deficiency syndrome,and three symptoms named diseases,including chest tightness,chest pain,insomnia,and head discomfort.Conclusions:Through cross-sectional design,the data obtained in this study revealed the actual situation of CHD patients with anxiety or depression at different stages.The influencing factors of CHD patients with depression or anxiety were analyzed through the collected cross-sectional information and further revealed the syndromic characteristics of CHD patients with depression or anxiety at different stages from the perspective of TCM syndromes.The data obtained provide a practical basis for further understanding the clinical characteristics of bicardiac diseases and for proposing treatment strategies in stages.
基金support provided by Shenyang Young and Middle-aged Science and Technology Innovation Talent Support Program(project number RC210346)the Liaoning Provincial Department of Education Project(project number Injc202011)the reviewer's advice and comments.What's more,we wish to express our thanks to those who have contributed their well-researched and valuable articles.
文摘The mismatch between the actual heat production of an air source heat pump (ASHP) and the instantaneous load of the building it heats is a critical cause of low energy efficiency. Research on the measured heating effect provides an effective approach to improve the energy efficiency of an ASHP. This study therefore focused on two small office buildings to explore the operating data describing the ASHP system source and load sides during the heating season. A sensitivity analysis was employed to explore the actual operational effects of the ASHP. Common problems associated with system operation were comprehensively identified, including the operation characteristics, energy efficiency coefficients, load characteristics, and energy consumption characteristics of the transmission and distribution systems. The effects of these problems were evaluated from three perspectives: integrated part load value (IPLV), system performance loss, and indoor environmental parameters. The results shows that the highest coefficient of performance (COP) of the ASHP in Building A was 3.27 while the IPLV was 2.68, operating status reached the standard. The COP value of the ASHP in Building B was 1.55 while the IPLV was 2.45. Poor value shows the low performance in operating phase, which can be further optimised by matching the building instantaneous load to the heat production of the ASHP, improves the operating effect of two buildings comprehensively.
基金supported by“Ministry of science and technology of Taiwan”,China.
文摘Head and neck(HN)cancer is an endemic disease in Taiwan,China.Locally recurrent HN cancer after full-dose irradia-tion poses a therapeutic challenge,and boron neutron capture therapy(BNCT)may be a solution that could provide durable local control with tolerable toxicity.The Tsing-Hua Open Pool Reactor(THOR)at National Tsing-Hua University in Hsin-Chu,provides a high-quality epithermal neutron source for basic and clinical BNCT research.Our first clinical trial,entitled“A phase I/II trial of boron neutron capture therapy for recurrent head and neck cancer at THOR”,was carried out between 2010 and 2013.A total of 17 patients with 23 recurrent HN tumors who had received high-dose photon irradiation were enrolled in the study.The fructose complex of l-boronophenylalanine was used as a boron carrier,and a two-fraction BNCT treatment regimen at 28-day intervals was used for each patient.Toxicity was acceptable,and although the response rate was high(12/17),re-recurrence within or near the radiation site was common.To obtain better local control,another clinical trial entitled“A phase I/II trial of boron neutron capture therapy combined with image-guided intensity-modulated radiotherapy(IG-IMRT)for locally recurrent HN cancer”was initiated in 2014.The first administration of BNCT was performed according to our previous protocol,and IG-IMRT was initiated 28 days after BNCT.As of May 2017,seven patients have been treated with this combination.The treatment-related toxicity was similar to that previously observed with two BNCT applications.Three patients had a complete response,but locoregional recurrence was the major cause of failure despite initially good responses.Future clinical trials combining BNCT with other local or systemic treatments will be carried out for recurrent HN cancer patients at THOR.
基金supported by the Fundamental Research Funds for the Central Scientific Research Institutes (Grant No. 20200306)。
文摘Aiming at the complex and restrictive characteristics of human resource allocation in multiple scientific university research projects, an improved pigeon-inspired optimization(IPIO) algorithm is proposed wherein loss minimization and the shortest project delay time are considered as optimization goals. Firstly, mathematical modelling of the problem is carried out, and the multi-objective optimization problem is transformed into a single-objective optimization problem by means of a weighted solution. In the second step, the traditional pigeon-inspired optimization(PIO) algorithm is discretized, and an adaptive parameter strategy is adopted to improve the shortcomings of the algorithm itself. Finally, by comparing the simulation results with the original algorithm and the genetic algorithm in the optimization of human resource allocation in multiple projects, the feasibility and superiority of the proposed algorithm in the optimization of human resource allocation in multi-scientific research projects is verified.
