The digital-intelligent era presents both opportunities and challenges for specialized course education in universities.Based on the fundamental task of fostering virtue through education,this study takes the course“...The digital-intelligent era presents both opportunities and challenges for specialized course education in universities.Based on the fundamental task of fostering virtue through education,this study takes the course“Design and Guidance of Science Play Performance Activities”as an example to explore practical pathways for integrating ideological and political education into specialized courses within a digital-intelligent context.Employing literature review and action research methodologies,the study constructs a digital-intelligent teaching model,develops digital ideological and political resources,innovates teaching methods,and systematically identifies and deeply integrates ideological and political elements into the curriculum.Through practical validation,the research summarizes a curriculum design framework grounded in Tyler’s principles and a digital-intelligent teaching model based on BOPPPS,providing transferable pathways for ideological and political education in specialized courses.Furthermore,it offers theoretical support and practical references for the deep integration and innovative application of digital-intelligent technologies in education.展开更多
An international survey of school-level geoscience education acquired data from 32 countries across the globe.Whilst the data is likely to be biased towards those countries which have geoscience educators active enoug...An international survey of school-level geoscience education acquired data from 32 countries across the globe.Whilst the data is likely to be biased towards those countries which have geoscience educators active enough to respond to the questionnaire survey,the data nevertheless shows that geoscience is taught in a wide variety of contexts across the world,linked to science,geography or both.The majority of children in the countries surveyed had compulsory geoscience education in their curricula,had national standards in geoscience education,and covered a reasonable level of geoscience terminology in their studies.展开更多
The purpose of this study is to investigate the effect of Panoramic Virtual Reality(PVR)applied to online earth science classes on students’learning flow.To this end,a PVR learning material was made with a geology le...The purpose of this study is to investigate the effect of Panoramic Virtual Reality(PVR)applied to online earth science classes on students’learning flow.To this end,a PVR learning material was made with a geology learning site,which contains a core geologic concept contained in a high school curriculum in Korea.To this end,a PVR learning material was made at a geologic field site to provide an interactive and engaging way for students to grasp core geologic concepts according to the high school curriculum in Korea.The PVR was applied to online earth science classes with 45 high school students.In order to examine the effect of the PVR on students'learning flow,pre-post learning flow test papers were used,then matchedsample t-test analysis and students'responses were analyzed.The result shows online classes with PVR have positive effects on learning flow(p<0.05).And it was possible for the students to observe three-dimensional geologic structures effectively in online classes as in offline field trips.And the students'responded with positive feedbacks.These suggest that PVR in online classes can be used as an effective teaching method,which can improve students'flow and eventually understanding subjects.展开更多
Pyrethroids are a class of novel broad-spectrum pesticides synthesized to mimic natural pyrethrins.Due to their high efficiency,low toxicity,and safety,pyrethroids have been widely used as alternatives to organophosph...Pyrethroids are a class of novel broad-spectrum pesticides synthesized to mimic natural pyrethrins.Due to their high efficiency,low toxicity,and safety,pyrethroids have been widely used as alternatives to organophosphate and carbamate insecticides in the control of agricultural and sanitary pests.However,with the increasing use of pyrethroid pesticides,the resulting pesticide residues have posed threats to both the environment and human health.Biodegradation is considered one of the most promising methods for the removal of pyrethroids,and significant research has been conducted in this area.This review summarizes recent advances in the biodegradation of pyrethroids,including degradation by single strains,microbial consortia,and enzymes.It provides an in-depth analysis of the biodegradation pathways and catalytic mechanisms involved in the degradation of pyrethroids and outlines enhancement strategies for improving the activity of pyrethroid-degrading enzymes.The review also identifies current challenges in pyrethroid biodegradation and offers perspectives for future research.This review serves as a valuable reference for subsequent studies on pyrethroid biodegradation.展开更多
BACKGROUND Parkinson’s disease(PD)is a common neurodegenerative disorder in the elderly population.Non-motor symptoms such as anxiety and depression are often subtle,hindering early detection and intervention,yet the...BACKGROUND Parkinson’s disease(PD)is a common neurodegenerative disorder in the elderly population.Non-motor symptoms such as anxiety and depression are often subtle,hindering early detection and intervention,yet they markedly affect quality of life and clinical outcomes.AIM To investigate the prevalence of anxiety and depression in elderly PD patients,identify associated risk factors,and assess their relationship with fatigue severity.METHODS A cross-sectional analysis was conducted in 123 elderly PD patients treated at The Second Rehabilitation Hospital of Shanghai between January 2023 and December 2024.Demographic and clinical data were obtained using standardized questionnaires.Anxiety,depression,and fatigue were assessed using the Beck Anxiety Inventory(BAI),Geriatric Depression Scale(GDS),and Fatigue Scale-14(FS-14),respectively.Binary logistic regression identified risk factors for anxiety and depression,whereas Spearman’s correlation assessed associations with fatigue.RESULTS Anxiety and depression prevalence rates were 64.2%(mean BAI score:19.59±10.92)and 56.1%(mean GDS score:12.82±6.37),respectively.The mean FS-14 total score was 9.46±1.89,comprising physical(5.77±1.51)and mental(3.69±1.20)fatigue components.Significant positive correlations were observed between fatigue scores(total,physical,and mental)and both anxiety and depression(all P<0.05).Univariate analysis revealed statistically significant associations between anxiety/depression and monthly income,disease duration,and disease severity(all P<0.05).Multivariate logistic regression indicated higher anxiety risk in patients with lower monthly income,prolonged disease duration,advanced disease severity,or multimorbidity.Depression risk was elevated in patients with lower monthly income and severe disease,whereas longer disease duration unexpectedly served as a protective factor.CONCLUSION Elderly PD patients show high rates of anxiety and depression,both of which are significantly correlated with fatigue severity.These findings highlight the importance of psychological monitoring and targeted mental health interventions in PD management among the elderly.展开更多
Hepatitis B Virus(HBV)infection and heavy alcohol consumption are the two primary pathogenic causes of liver cirrhosis.In this paper,we proposed a deterministic mathematical model and a logistic equation to investigat...Hepatitis B Virus(HBV)infection and heavy alcohol consumption are the two primary pathogenic causes of liver cirrhosis.In this paper,we proposed a deterministic mathematical model and a logistic equation to investigate the dynamics of liver cirrhosis progression as well as to explain the implications of variations in alcohol consumption on chronic hepatitis B patients,respectively.The intricate interactions between liver cirrhosis,recovery,and treatment dynamics are captured by the model.This study aims to show that alcohol consumption by Hepatitis B-infected individuals accelerates liver cirrhosis progression while treatment of acutely infected individuals reduces it.We proved that a unique solution of the proposed model exists,which is positive and bounded.Using the next-generation matrix approach,two basic reproductive numbers R_(A_(0))and R_(A_(max))are calculated to identify future recurrence.The equilibrium points are calculated,and both equilibria are proved locally and globally asymptotically stable when R_(0)is below and above one,respectively.It is shown that bifurcation exists at R_(0)=1 and a detailed proof for forward bifurcation is given.Furthermore,we performed the sensitivity analysis of the model parameters on R_(0).For the confirmation of analytical work,we performed numerical simulations,and the results indicate that the treatment and the inhibitory effects reduce the risk of developing liver cirrhosis in individuals,while heavy alcohol consumption accelerates markedly the liver cirrhosis progression in patients with chronic hepatitis B.展开更多
The preparation of ionic liquid gel electrolyte can reduce the occurrence of side effects and extend battery life.In the DMSO-ILZE electrolyte composed of DMSO,1-ethyl-3-methylimidazole tetrafluoroborate(EMIMBF_(4))an...The preparation of ionic liquid gel electrolyte can reduce the occurrence of side effects and extend battery life.In the DMSO-ILZE electrolyte composed of DMSO,1-ethyl-3-methylimidazole tetrafluoroborate(EMIMBF_(4))and Zn(BF_(4))_(2),the supramolecular gelatorβ-cyclodextrin(β-CD)was added,and then a gel electrolyte(CD-ILZE)for zinc-ion batteries was prepared through host-vip interaction betweenβ-CD and DMSO-ILZE electrolyte.The gel electrolyte has good conductivity between-30 and 80℃,which is found by fitting the Arrhenius equation that the gel electrolyte satisfies the liquid law within this temperature range.In addition,the supramolecular gel electrolyte can effectively decrease hydrogen evolution corrosion and the formation of zinc dendrites.Compared with the battery prepared by DMSO-ILZE electrolyte(about 1100 h),the prepared Zn||Zn battery exhibits a more stable cycle(over 2800 h)at a current density of 0.5 m A·cm^(-2).At 0.1 A·g^(-1),the prepared Zn||V_(2)O_(5)gel electrolyte cell has a capacity of 30 m Ah·g^(-1)and a capacity retention rate of 85.17%after more than 1500 cycles.The CD-ILZE supramolecular gel electrolyte can inhibit the formation of hydrogen evolution corrosion and zinc dendrites,and improve the cycling performance of the battery.展开更多
High-entropy materials(HEMs)have attracted considerable research attention in battery applications due to exceptional properties such as remarkable structural stability,enhanced ionic conductivity,superior mechanical ...High-entropy materials(HEMs)have attracted considerable research attention in battery applications due to exceptional properties such as remarkable structural stability,enhanced ionic conductivity,superior mechanical strength,and outstanding catalytic activity.These distinctive characteristics render HEMs highly suitable for various battery components,such as electrodes,electrolytes,and catalysts.This review systematically examines recent advances in the application of HEMs for energy storage,beginning with fundamental concepts,historical development,and key definitions.Three principal categories of HEMs,namely high-entropy alloys,high-entropy oxides,and highentropy MXenes,are analyzed with a focus on electrochemical performance metrics such as specific capacity,energy density,cycling stability,and rate capability.The underlying mechanisms by which these materials enhance battery performance are elucidated in the discussion.Furthermore,the pivotal role of machine learning in accelerating the discovery and optimization of novel high-entropy battery materials is highlighted.The review concludes by outlining future research directions and potential breakthroughs in HEM-based battery technologies.展开更多
Silica nanoparticles-stabilized cobalt and nitrogen-doped carbon materials were synthesized through pyrolysis of metal-organic-framework of ZIF-67 supported by silica nanoparticles.The experimental results reveal that...Silica nanoparticles-stabilized cobalt and nitrogen-doped carbon materials were synthesized through pyrolysis of metal-organic-framework of ZIF-67 supported by silica nanoparticles.The experimental results reveal that the introduction of the silica nanoparticles can stabilize the microstructure of the derived CoN-C materials,which in turn exhibits the promising electrocatalytic activity towards both oxygen reduction and oxygen evolution reactions.The optimized sample exhibits a better oxygen reduction activity than commercial Pt/C catalyst as confirmed by the positive shift of half-wave potential by 20 mV while it has a low overpotential of 273 mV for oxygen evolution reactions with the retained performance over 80%after 25,000 s of continuous operation.It is demonstrated that the introduction of support frame might be an effective way to improve the activity and stability of metal-organic-framework derived electrocatalyst with stabilized microstructure.展开更多
Purpose:ATLAS is a cross-sectional study aiming to investigate environmental and genetic determinants of athletic performance in healthy Greek competitive athletes(CA).This article presents the study design,investigat...Purpose:ATLAS is a cross-sectional study aiming to investigate environmental and genetic determinants of athletic performance in healthy Greek competitive athletes(CA).This article presents the study design,investigates the muscle strength performance(MSP)of 289 adult and teenage CA,exercisers,and physically inactive individuals(PI),and proposes predictive models of MSP for adults.Methods:Muscle maximal,speed,and explosive strength(MMS/MSS/MES)at unilateral maximal concentric flexion and extension contraction(FC/EC)were evaluated using Biodex System 3 PRO^(TM)at 60°/s,180°/s,and 300°/s,while additional performance markers were assessed through field ergometric testing.Participants were interviewed about their lifestyle,dietary habits,physical activity,injury,and medical history.Body composition was assessed via bioelectrical impedance.gDNA was extracted from biochemical samples and then genotyped.Statistical analysis was conducted using IBM SPSS Statistics v21.0 and R.Results:Age,fitness,and sex impacted correlations of MSP with body composition and anthropometric measurements(p<0.05).Among CA,females outperformed males in accuracy(p<0.001)while,males outperformed females in anaerobic power,MSP,speed,and endurance(p<0.001).Adult CA outperformed exercisers and PI in MMS,MSS,and MES(p<0.05).Multiple linear regression models,with predictors age,FFM,body extremity,training load explained the majority of variation in MMS(R^(2)_(adj):71.4%–88.9%),MSS(R^(2)_(adj):64.8%–78.4%),and MES(R^(2)_(adj):52.7%–68.4%)at EC,FC,and their mean(p<0.001).Conclusions:Muscle-strengthening strategies should be customized according to individual fitness levels,body composition,and anthropometric measurements.The innovative sex-specific regression models assessing MMS,MSS,and MES at EC and FC provide a framework for personalizing rehabilitation and skill-specific training strategies.展开更多
Shorebirds migrate long-distances along the East Asian-Australasian Flyway(EAAF),exhibiting distinct spatiotemporal fluctuations in population dynamics.Because of habitat degradation and population declines at key sto...Shorebirds migrate long-distances along the East Asian-Australasian Flyway(EAAF),exhibiting distinct spatiotemporal fluctuations in population dynamics.Because of habitat degradation and population declines at key stopover sites along the EAAF,the South Korea's coastal wetlands have gained increasing attention for their ecological value.This study analyzed the shorebird population dynamics across 35 coastal wetlands in South Korea from 2016 to 2024 using data from the National Marine Ecosystem Monitoring Program.For the timeseries analysis,we employed three indicators:seasonal chan ges in abundance,short-term fluctuations(Fi),and long-term trends,assessed using the TRends and Indices for Monitoring data(TRIM)model.Abundance,species richness,and Shannon diversity indices were assessed across the regions during spring and autumn.The TRIM results revealed significant population increases in both seasons("Strong increase"in spring and"Moderate increase"in autumn).Species-level trends indicated notable increases in large-bodied shorebirds,including globally threatened species such as the Far Eastern Curlew(Numenius madagascariensis).Eurasian Curlew(N.arquata),and Eurasian Oystercatcher(Haematopus ostralegus),whereas other species showed variable responses.The Yellow Sea region(Gyeonggi,Chungcheong,and Western Jeolla)showed high biodiversity indices in spring,which may be associated with time-minimization strategies,whereas autumn patterns were characterized by more flexible and selective stopover use,possibly related to energy-minimization strategies.The East Coast and Jeju regions showed the lowest biodiversity indices.Furthermore,community-level analyses using Non-metric Multidimensional Scaling(NMDS)and PERMANOVA revealed distinct clustering of bird assemblages by macro-region and season,confirming significant spatial differentiation in community composition.These findings contrast with the broader declining trends reported across the EAAF and suggest that South Korea's coastal wetlands may serve as stable alternative stopover habitats,potentially supporting the redistribution or recovery of some species.This study highlights the importance of transboundary cooperation and region-specific habitat management that reflects local ecological contexts for effective conservation.展开更多
In this investigation,a hybrid approach integrating the IDDES turbulence model and FW-H is employed to forecast the hydroacoustic of the rim driven thruster(RDT)under non-cavitation and uniform flow conditions at vary...In this investigation,a hybrid approach integrating the IDDES turbulence model and FW-H is employed to forecast the hydroacoustic of the rim driven thruster(RDT)under non-cavitation and uniform flow conditions at varying loading conditions(J=0.3 and J=0.6).It is revealed that the quadrupole term contribution in the P-FWH method significantly affects the monopole term in the low-frequency region,while it mainly affects the dipole term in the high-frequency region.Specifically,the overall sound pressure levels(SPL)of the RDT using the P-FWH method are 2.27 dB,10.03 dB,and 16.73 dB at the receiving points from R1 to R3 under the heavy-loaded condition,while they increase by 0.67 dB at R1,and decrease by 14.93 dB at R2,and 22.20 dB at R3,for the light-loaded condition.The study also utilizes the pressure-time derivatives to visualize the numerical noise and to pinpoint the dynamics of the vortex cores,and the optimization of the grid design can significantly reduce the numerical noise.The computational accuracy of the P-FWH method can meet the noise requirements for the preliminary design of rim driven thrusters.展开更多
Alkali-free SiO_(2)-Al_(2)O_(3)-CaO-MgO with different SiO_(2)/Al_(2)O_(3)mass ratios was prepared by conventional melt quenching method.The glass network structure,thermodynamic properties and elastic modulus changes...Alkali-free SiO_(2)-Al_(2)O_(3)-CaO-MgO with different SiO_(2)/Al_(2)O_(3)mass ratios was prepared by conventional melt quenching method.The glass network structure,thermodynamic properties and elastic modulus changes with SiO_(2)and Al_(2)O_(3)ratios were investigated using various techniques.It is found that when SiO_(2)is replaced by Al_(2)O_(3),the Q^(4) to Q^(3) transition of silicon-oxygen network decreases while the aluminum-oxygen network increases,which result in the transformation of Si-O-Si bonds to Si-O-Al bonds and an increase in glass network connectivity even though the intermolecular bond strength decreases.The glass transition temperature(T_(g))increases continuously,while the thermal expansion coefficient increases and high-temperature viscosity first decreases and then increases.Meanwhile,the elastic modulus values increase from 93 to 102 GPa.This indicates that the elastic modulus is mainly affected by packing factor and dissociation energy,and elements with higher packing factors and dissociation energies supplant those with lower values,resulting in increased rigidity within the glass.展开更多
Cuprous oxide(Cu_(2)O) is one of the most promising catalysts for electrochemical conversion of CO_(2) into value-added C_(2) products.The efficiency of CO_(2)-to-C_(2) conversion is highly dependent on the Cu_(2)O cr...Cuprous oxide(Cu_(2)O) is one of the most promising catalysts for electrochemical conversion of CO_(2) into value-added C_(2) products.The efficiency of CO_(2)-to-C_(2) conversion is highly dependent on the Cu_(2)O crystal plane orientation and the corresponding adsorbed ^(*)CO species.Herein,we constructed high-index crystal planes(311) in Cu_(2)O(CO-Cu_(2)O) via a facile self-selective CO-induced strategy under a CO atmosphere,which was verified by high-resolution transmission electron microscopy(HR-TEM) and atomic force microscopy(AFM) results.By exploiting the high surface energy of the high index crystal planes,^(*)CO species are stabilized in CO-Cu_(2)O during CO_(2)RR,resulting in exceptional catalytic performance for CO_(2)-to-C_(2)products.In situ infrared spectroscopy revealed that both atop-type(^(*)CO_(atop)) and hollow-type(^(*)CO_(hollow)) adsorption of ^(*)CO species occurred on the CO-Cu_(2)O.The asymmetric C-C coupling energy barrier between ^(*)CO_(atop) and ^(*)CO_(hollow) in(311) crystal plane decreases by 47.8 % compared to the symmetric coupling of ^(*)CO_(atop) in conventional(100) crystal planes.Consequently,the Faradaic efficiency of C_(2) products generated with CO-Cu_(2)O was increased by as high as 100 % compared to that with pristine Cu_(2)O.展开更多
Large-scale hydrogen production via water electrolysis faces a freshwater shortage.Direct seawater electrolysis offers a solution but encounters new challenges.Herein,we report a feasible strategy to both prevent meta...Large-scale hydrogen production via water electrolysis faces a freshwater shortage.Direct seawater electrolysis offers a solution but encounters new challenges.Herein,we report a feasible strategy to both prevent metal hydroxides deposition and boost the hydrogen evolution reaction by adding a chelating agent,EDTA-Na_(4),that chelates with Mg^(2+)/Ca^(2+),thus inhibiting their deposition and gathering them near the cathode surface,resulting in breaking the ordered hydrogen bond networks of interfacial water and reducing the activation energy of water dissociation.Furthermore,hydrolysis of–COO^(-) also promoted water dissociation to produce more active*H and*OH near the electrode surface that in turn serves as a diffusion medium for*OH,accelerating mass transfer and enabling seawater electrolysis to exhibit a stable performance,which operates continuously at 100 mA cm^(-2)@2.20 V and 200 mA cm^(-2)@2.58 V for 400 h in the symmetric electrolyzer and 500 mA cm^(-2)@2.29 V for over 500 h in the asymmetric electrolyzer.This study provides a new perspective to address the issues of stable and scalable direct seawater electrolysis for practical green hydrogen production.展开更多
Host-yeast interactions are fundamental drivers of human microbiome dynamics,spanning a spectrum from mutualistic symbiosis to opportunistic pathogenesis with profound implications for systemic health.This review syst...Host-yeast interactions are fundamental drivers of human microbiome dynamics,spanning a spectrum from mutualistic symbiosis to opportunistic pathogenesis with profound implications for systemic health.This review systematically elucidates the complex molecular mechanisms governing these relationships,with a specific focus on metabolic interdependence and immunomodulation.We analyze how yeast-derived metabolites,particularly short-chain fatty acids(SCFAs),modulate host glucose and lipid homeostasis via signaling pathways such as GPR41/43 and GLP-1 secretion.Furthermore,the review explores the pathophysiological role of fungal dysbiosis in chronic conditions,including obesity,diabetes,and inflammatory bowel disease(IBD),highlighting how a breakdown in host-yeast homeostasis triggers pro-inflammatory cascades.Beyond the fungal-host axis,we introduce the concept of the"mycobiome-virome-bacterial axis,"discussing how commensal yeasts synergize with beneficial bacteria like Bifidobacterium and influence viral infectivity through Interferon-mediated innate immune priming.We critically evaluate how cutting-edge technologies-including transgenic mouse models(specifically Dectin-1^(-/-)and CARD9^(-/-),metabolomics,and single-cell sequencing-have revolutionized our mechanistic understanding of these multi-kingdom dynamics.By integrating current findings,we identify critical knowledge gaps and propose high-resolution research frameworks,such as humanized organ-on-a-chip systems,to simulate intricate host-microbe interactions under physiological flow conditions.This comprehensive synthesis provides a strategic foundation for developing targeted,next-generation microbiome-based interventions to restore host-yeast balance and enhance overall human health.展开更多
Abstract Problems in agricultural science and technology service system were ana- lyzed, such as system problem, investment and worker quality, and based on this countermeasures were proposed, so as to promote the dev...Abstract Problems in agricultural science and technology service system were ana- lyzed, such as system problem, investment and worker quality, and based on this countermeasures were proposed, so as to promote the development of modern agri- culture and construction of new countryside.展开更多
To comprehensively understand the Arctic and Antarctic upper atmosphere, it is often crucial to analyze various data that are obtained from many regions. Infrastructure that promotes such interdisciplinary studies on ...To comprehensively understand the Arctic and Antarctic upper atmosphere, it is often crucial to analyze various data that are obtained from many regions. Infrastructure that promotes such interdisciplinary studies on the upper atmosphere has been developed by a Japanese inter-university project called the Inter-university Upper atmosphere Global Observation Network （1UGONET）. The objective of this paper is to describe the infrastructure and tools developed by IUGONET. We focus on the data analysis software. It is written in Interactive Data Language （IDL） and is a plug-in for the THEMIS Data Analysis Software suite （TDAS）, which is a set of IDL libraries used to visualize and analyze satellite- and ground-based data. We present plots of upper atmospheric data provided by IUGONET as examples of applications, and verify the usefulness of the software in the study of polar science. We discuss IUGONET＇s new and unique developments, i.e., an executable file of TDAS that can run on the IDL Virtual Machine, IDL routines to retrieve metadata from the IUGONET database, and an archive of 3-D simulation data that uses the Common Data Format so that it can easily be used with TDAS.展开更多
The study based on radical constructivism seeks to identify Semester Two Accounting Courses students’ meaning of ogive. Data for this study include verbal and non-verbal information gathered from three students of Se...The study based on radical constructivism seeks to identify Semester Two Accounting Courses students’ meaning of ogive. Data for this study include verbal and non-verbal information gathered from three students of Semester Two Accounting Courses in clinical interview sessions. The research participants have identified four processes performed on the basic elements to produce an ogive. In addition, five categories of products used by research participants to describe the ogive were identified.展开更多
基金funded by the Scientific Research Project of Lingnan Normal Universitythe following projects and centers at Lingnan Normal University:the Special Project on Party Building and Ideological-Political Education—“Practical Research on‘Curriculum Ideology and Politics’in Universities under the Concept of‘Three-Wide Education’”(WD2424)+1 种基金the Science Education Special Project—“Research on Implementation Strategies for High-Quality Development of Science Popularization Education Based on Scientific Activities”(KX2404)the Ideological-Political Education Teaching Demonstration Center of the School of Physics(PX-4825706).
文摘The digital-intelligent era presents both opportunities and challenges for specialized course education in universities.Based on the fundamental task of fostering virtue through education,this study takes the course“Design and Guidance of Science Play Performance Activities”as an example to explore practical pathways for integrating ideological and political education into specialized courses within a digital-intelligent context.Employing literature review and action research methodologies,the study constructs a digital-intelligent teaching model,develops digital ideological and political resources,innovates teaching methods,and systematically identifies and deeply integrates ideological and political elements into the curriculum.Through practical validation,the research summarizes a curriculum design framework grounded in Tyler’s principles and a digital-intelligent teaching model based on BOPPPS,providing transferable pathways for ideological and political education in specialized courses.Furthermore,it offers theoretical support and practical references for the deep integration and innovative application of digital-intelligent technologies in education.
文摘An international survey of school-level geoscience education acquired data from 32 countries across the globe.Whilst the data is likely to be biased towards those countries which have geoscience educators active enough to respond to the questionnaire survey,the data nevertheless shows that geoscience is taught in a wide variety of contexts across the world,linked to science,geography or both.The majority of children in the countries surveyed had compulsory geoscience education in their curricula,had national standards in geoscience education,and covered a reasonable level of geoscience terminology in their studies.
基金supported by the research grant of the Kongju National University in 2023.
文摘The purpose of this study is to investigate the effect of Panoramic Virtual Reality(PVR)applied to online earth science classes on students’learning flow.To this end,a PVR learning material was made with a geology learning site,which contains a core geologic concept contained in a high school curriculum in Korea.To this end,a PVR learning material was made at a geologic field site to provide an interactive and engaging way for students to grasp core geologic concepts according to the high school curriculum in Korea.The PVR was applied to online earth science classes with 45 high school students.In order to examine the effect of the PVR on students'learning flow,pre-post learning flow test papers were used,then matchedsample t-test analysis and students'responses were analyzed.The result shows online classes with PVR have positive effects on learning flow(p<0.05).And it was possible for the students to observe three-dimensional geologic structures effectively in online classes as in offline field trips.And the students'responded with positive feedbacks.These suggest that PVR in online classes can be used as an effective teaching method,which can improve students'flow and eventually understanding subjects.
基金supported by grants from the National Natural Science Foundation of China(No.42207148)the Science and Technology Plan Project of Quanzhou,China(Nos.2025QZNS002 and 2022N030)+2 种基金the Natural Science Foundation of Fujian Province,China(No.2022J01573)the Educational Research Project for Young and Middle-Aged Teachers in Fujian Province,China(No.JAT210042)the Open Project Fund of Key Laboratory of Marine Biological Resources,Ministry of Natural Resources of China(Nos.HY202201 and HY202202)。
文摘Pyrethroids are a class of novel broad-spectrum pesticides synthesized to mimic natural pyrethrins.Due to their high efficiency,low toxicity,and safety,pyrethroids have been widely used as alternatives to organophosphate and carbamate insecticides in the control of agricultural and sanitary pests.However,with the increasing use of pyrethroid pesticides,the resulting pesticide residues have posed threats to both the environment and human health.Biodegradation is considered one of the most promising methods for the removal of pyrethroids,and significant research has been conducted in this area.This review summarizes recent advances in the biodegradation of pyrethroids,including degradation by single strains,microbial consortia,and enzymes.It provides an in-depth analysis of the biodegradation pathways and catalytic mechanisms involved in the degradation of pyrethroids and outlines enhancement strategies for improving the activity of pyrethroid-degrading enzymes.The review also identifies current challenges in pyrethroid biodegradation and offers perspectives for future research.This review serves as a valuable reference for subsequent studies on pyrethroid biodegradation.
基金Supported by Foundation of Shanghai Baoshan Science and Technology Commission,No.2024-E-66Shanghai Nursing Association Scientific Research Project,No.2024MS-B02.
文摘BACKGROUND Parkinson’s disease(PD)is a common neurodegenerative disorder in the elderly population.Non-motor symptoms such as anxiety and depression are often subtle,hindering early detection and intervention,yet they markedly affect quality of life and clinical outcomes.AIM To investigate the prevalence of anxiety and depression in elderly PD patients,identify associated risk factors,and assess their relationship with fatigue severity.METHODS A cross-sectional analysis was conducted in 123 elderly PD patients treated at The Second Rehabilitation Hospital of Shanghai between January 2023 and December 2024.Demographic and clinical data were obtained using standardized questionnaires.Anxiety,depression,and fatigue were assessed using the Beck Anxiety Inventory(BAI),Geriatric Depression Scale(GDS),and Fatigue Scale-14(FS-14),respectively.Binary logistic regression identified risk factors for anxiety and depression,whereas Spearman’s correlation assessed associations with fatigue.RESULTS Anxiety and depression prevalence rates were 64.2%(mean BAI score:19.59±10.92)and 56.1%(mean GDS score:12.82±6.37),respectively.The mean FS-14 total score was 9.46±1.89,comprising physical(5.77±1.51)and mental(3.69±1.20)fatigue components.Significant positive correlations were observed between fatigue scores(total,physical,and mental)and both anxiety and depression(all P<0.05).Univariate analysis revealed statistically significant associations between anxiety/depression and monthly income,disease duration,and disease severity(all P<0.05).Multivariate logistic regression indicated higher anxiety risk in patients with lower monthly income,prolonged disease duration,advanced disease severity,or multimorbidity.Depression risk was elevated in patients with lower monthly income and severe disease,whereas longer disease duration unexpectedly served as a protective factor.CONCLUSION Elderly PD patients show high rates of anxiety and depression,both of which are significantly correlated with fatigue severity.These findings highlight the importance of psychological monitoring and targeted mental health interventions in PD management among the elderly.
文摘Hepatitis B Virus(HBV)infection and heavy alcohol consumption are the two primary pathogenic causes of liver cirrhosis.In this paper,we proposed a deterministic mathematical model and a logistic equation to investigate the dynamics of liver cirrhosis progression as well as to explain the implications of variations in alcohol consumption on chronic hepatitis B patients,respectively.The intricate interactions between liver cirrhosis,recovery,and treatment dynamics are captured by the model.This study aims to show that alcohol consumption by Hepatitis B-infected individuals accelerates liver cirrhosis progression while treatment of acutely infected individuals reduces it.We proved that a unique solution of the proposed model exists,which is positive and bounded.Using the next-generation matrix approach,two basic reproductive numbers R_(A_(0))and R_(A_(max))are calculated to identify future recurrence.The equilibrium points are calculated,and both equilibria are proved locally and globally asymptotically stable when R_(0)is below and above one,respectively.It is shown that bifurcation exists at R_(0)=1 and a detailed proof for forward bifurcation is given.Furthermore,we performed the sensitivity analysis of the model parameters on R_(0).For the confirmation of analytical work,we performed numerical simulations,and the results indicate that the treatment and the inhibitory effects reduce the risk of developing liver cirrhosis in individuals,while heavy alcohol consumption accelerates markedly the liver cirrhosis progression in patients with chronic hepatitis B.
文摘The preparation of ionic liquid gel electrolyte can reduce the occurrence of side effects and extend battery life.In the DMSO-ILZE electrolyte composed of DMSO,1-ethyl-3-methylimidazole tetrafluoroborate(EMIMBF_(4))and Zn(BF_(4))_(2),the supramolecular gelatorβ-cyclodextrin(β-CD)was added,and then a gel electrolyte(CD-ILZE)for zinc-ion batteries was prepared through host-vip interaction betweenβ-CD and DMSO-ILZE electrolyte.The gel electrolyte has good conductivity between-30 and 80℃,which is found by fitting the Arrhenius equation that the gel electrolyte satisfies the liquid law within this temperature range.In addition,the supramolecular gel electrolyte can effectively decrease hydrogen evolution corrosion and the formation of zinc dendrites.Compared with the battery prepared by DMSO-ILZE electrolyte(about 1100 h),the prepared Zn||Zn battery exhibits a more stable cycle(over 2800 h)at a current density of 0.5 m A·cm^(-2).At 0.1 A·g^(-1),the prepared Zn||V_(2)O_(5)gel electrolyte cell has a capacity of 30 m Ah·g^(-1)and a capacity retention rate of 85.17%after more than 1500 cycles.The CD-ILZE supramolecular gel electrolyte can inhibit the formation of hydrogen evolution corrosion and zinc dendrites,and improve the cycling performance of the battery.
基金supported by the Fujian Provincial Science and Technology Planning Project(No.2022HZ027006,No.2024HZ021023)National Natural Science Foundation of China(No.U22A20118).
文摘High-entropy materials(HEMs)have attracted considerable research attention in battery applications due to exceptional properties such as remarkable structural stability,enhanced ionic conductivity,superior mechanical strength,and outstanding catalytic activity.These distinctive characteristics render HEMs highly suitable for various battery components,such as electrodes,electrolytes,and catalysts.This review systematically examines recent advances in the application of HEMs for energy storage,beginning with fundamental concepts,historical development,and key definitions.Three principal categories of HEMs,namely high-entropy alloys,high-entropy oxides,and highentropy MXenes,are analyzed with a focus on electrochemical performance metrics such as specific capacity,energy density,cycling stability,and rate capability.The underlying mechanisms by which these materials enhance battery performance are elucidated in the discussion.Furthermore,the pivotal role of machine learning in accelerating the discovery and optimization of novel high-entropy battery materials is highlighted.The review concludes by outlining future research directions and potential breakthroughs in HEM-based battery technologies.
基金Funded by the National Natural Science Foundation of China Guangdong(No.22279096)。
文摘Silica nanoparticles-stabilized cobalt and nitrogen-doped carbon materials were synthesized through pyrolysis of metal-organic-framework of ZIF-67 supported by silica nanoparticles.The experimental results reveal that the introduction of the silica nanoparticles can stabilize the microstructure of the derived CoN-C materials,which in turn exhibits the promising electrocatalytic activity towards both oxygen reduction and oxygen evolution reactions.The optimized sample exhibits a better oxygen reduction activity than commercial Pt/C catalyst as confirmed by the positive shift of half-wave potential by 20 mV while it has a low overpotential of 273 mV for oxygen evolution reactions with the retained performance over 80%after 25,000 s of continuous operation.It is demonstrated that the introduction of support frame might be an effective way to improve the activity and stability of metal-organic-framework derived electrocatalyst with stabilized microstructure.
文摘Purpose:ATLAS is a cross-sectional study aiming to investigate environmental and genetic determinants of athletic performance in healthy Greek competitive athletes(CA).This article presents the study design,investigates the muscle strength performance(MSP)of 289 adult and teenage CA,exercisers,and physically inactive individuals(PI),and proposes predictive models of MSP for adults.Methods:Muscle maximal,speed,and explosive strength(MMS/MSS/MES)at unilateral maximal concentric flexion and extension contraction(FC/EC)were evaluated using Biodex System 3 PRO^(TM)at 60°/s,180°/s,and 300°/s,while additional performance markers were assessed through field ergometric testing.Participants were interviewed about their lifestyle,dietary habits,physical activity,injury,and medical history.Body composition was assessed via bioelectrical impedance.gDNA was extracted from biochemical samples and then genotyped.Statistical analysis was conducted using IBM SPSS Statistics v21.0 and R.Results:Age,fitness,and sex impacted correlations of MSP with body composition and anthropometric measurements(p<0.05).Among CA,females outperformed males in accuracy(p<0.001)while,males outperformed females in anaerobic power,MSP,speed,and endurance(p<0.001).Adult CA outperformed exercisers and PI in MMS,MSS,and MES(p<0.05).Multiple linear regression models,with predictors age,FFM,body extremity,training load explained the majority of variation in MMS(R^(2)_(adj):71.4%–88.9%),MSS(R^(2)_(adj):64.8%–78.4%),and MES(R^(2)_(adj):52.7%–68.4%)at EC,FC,and their mean(p<0.001).Conclusions:Muscle-strengthening strategies should be customized according to individual fitness levels,body composition,and anthropometric measurements.The innovative sex-specific regression models assessing MMS,MSS,and MES at EC and FC provide a framework for personalizing rehabilitation and skill-specific training strategies.
文摘Shorebirds migrate long-distances along the East Asian-Australasian Flyway(EAAF),exhibiting distinct spatiotemporal fluctuations in population dynamics.Because of habitat degradation and population declines at key stopover sites along the EAAF,the South Korea's coastal wetlands have gained increasing attention for their ecological value.This study analyzed the shorebird population dynamics across 35 coastal wetlands in South Korea from 2016 to 2024 using data from the National Marine Ecosystem Monitoring Program.For the timeseries analysis,we employed three indicators:seasonal chan ges in abundance,short-term fluctuations(Fi),and long-term trends,assessed using the TRends and Indices for Monitoring data(TRIM)model.Abundance,species richness,and Shannon diversity indices were assessed across the regions during spring and autumn.The TRIM results revealed significant population increases in both seasons("Strong increase"in spring and"Moderate increase"in autumn).Species-level trends indicated notable increases in large-bodied shorebirds,including globally threatened species such as the Far Eastern Curlew(Numenius madagascariensis).Eurasian Curlew(N.arquata),and Eurasian Oystercatcher(Haematopus ostralegus),whereas other species showed variable responses.The Yellow Sea region(Gyeonggi,Chungcheong,and Western Jeolla)showed high biodiversity indices in spring,which may be associated with time-minimization strategies,whereas autumn patterns were characterized by more flexible and selective stopover use,possibly related to energy-minimization strategies.The East Coast and Jeju regions showed the lowest biodiversity indices.Furthermore,community-level analyses using Non-metric Multidimensional Scaling(NMDS)and PERMANOVA revealed distinct clustering of bird assemblages by macro-region and season,confirming significant spatial differentiation in community composition.These findings contrast with the broader declining trends reported across the EAAF and suggest that South Korea's coastal wetlands may serve as stable alternative stopover habitats,potentially supporting the redistribution or recovery of some species.This study highlights the importance of transboundary cooperation and region-specific habitat management that reflects local ecological contexts for effective conservation.
基金The National Natural Science Foundation of China(Grant No.52201376)the Natural Science Foundation of Hubei Province,China(Grant No.2023AFB683).
文摘In this investigation,a hybrid approach integrating the IDDES turbulence model and FW-H is employed to forecast the hydroacoustic of the rim driven thruster(RDT)under non-cavitation and uniform flow conditions at varying loading conditions(J=0.3 and J=0.6).It is revealed that the quadrupole term contribution in the P-FWH method significantly affects the monopole term in the low-frequency region,while it mainly affects the dipole term in the high-frequency region.Specifically,the overall sound pressure levels(SPL)of the RDT using the P-FWH method are 2.27 dB,10.03 dB,and 16.73 dB at the receiving points from R1 to R3 under the heavy-loaded condition,while they increase by 0.67 dB at R1,and decrease by 14.93 dB at R2,and 22.20 dB at R3,for the light-loaded condition.The study also utilizes the pressure-time derivatives to visualize the numerical noise and to pinpoint the dynamics of the vortex cores,and the optimization of the grid design can significantly reduce the numerical noise.The computational accuracy of the P-FWH method can meet the noise requirements for the preliminary design of rim driven thrusters.
基金Supported by the National Key Research Program(No.2024-1129-954-112)National Natural Science Foundation of China(No.52372033)Guangxi Science and Technology Major Program(No.AA24263054)。
文摘Alkali-free SiO_(2)-Al_(2)O_(3)-CaO-MgO with different SiO_(2)/Al_(2)O_(3)mass ratios was prepared by conventional melt quenching method.The glass network structure,thermodynamic properties and elastic modulus changes with SiO_(2)and Al_(2)O_(3)ratios were investigated using various techniques.It is found that when SiO_(2)is replaced by Al_(2)O_(3),the Q^(4) to Q^(3) transition of silicon-oxygen network decreases while the aluminum-oxygen network increases,which result in the transformation of Si-O-Si bonds to Si-O-Al bonds and an increase in glass network connectivity even though the intermolecular bond strength decreases.The glass transition temperature(T_(g))increases continuously,while the thermal expansion coefficient increases and high-temperature viscosity first decreases and then increases.Meanwhile,the elastic modulus values increase from 93 to 102 GPa.This indicates that the elastic modulus is mainly affected by packing factor and dissociation energy,and elements with higher packing factors and dissociation energies supplant those with lower values,resulting in increased rigidity within the glass.
基金the financial support from the National Natural Science Foundation of China (Nos.U23A20677,22022610 and 52400137)"Pioneer" and "Leading Goose" R&D Program of Zhejiang (Nos.2022C03146 and 2023C03017)+2 种基金China Postdoctoral Science Foundation (No.2024T170805)Zhejiang Provincial Natural Science Foundation of China (No.LDT23E06015B06)the support of the Research Computing Center in College of Chemical and Biological Engineering at Zhejiang University for assistance with the calculations。
文摘Cuprous oxide(Cu_(2)O) is one of the most promising catalysts for electrochemical conversion of CO_(2) into value-added C_(2) products.The efficiency of CO_(2)-to-C_(2) conversion is highly dependent on the Cu_(2)O crystal plane orientation and the corresponding adsorbed ^(*)CO species.Herein,we constructed high-index crystal planes(311) in Cu_(2)O(CO-Cu_(2)O) via a facile self-selective CO-induced strategy under a CO atmosphere,which was verified by high-resolution transmission electron microscopy(HR-TEM) and atomic force microscopy(AFM) results.By exploiting the high surface energy of the high index crystal planes,^(*)CO species are stabilized in CO-Cu_(2)O during CO_(2)RR,resulting in exceptional catalytic performance for CO_(2)-to-C_(2)products.In situ infrared spectroscopy revealed that both atop-type(^(*)CO_(atop)) and hollow-type(^(*)CO_(hollow)) adsorption of ^(*)CO species occurred on the CO-Cu_(2)O.The asymmetric C-C coupling energy barrier between ^(*)CO_(atop) and ^(*)CO_(hollow) in(311) crystal plane decreases by 47.8 % compared to the symmetric coupling of ^(*)CO_(atop) in conventional(100) crystal planes.Consequently,the Faradaic efficiency of C_(2) products generated with CO-Cu_(2)O was increased by as high as 100 % compared to that with pristine Cu_(2)O.
基金the support from the National Key Research and Development Program of China(2023YFB4005000)the Joint Fund of Liaoning Binhai Laboratory(LBLF-2023-04)+3 种基金Dalian Science and Technology Talent Innovation Support Plan(2022RY09)Innovation Research Fund of Dalian Institute of Chemical Physics(DICP I202318)National Natural Science Foundation of China(22478384)the UK EPSRC(EP/W03784X/1)。
文摘Large-scale hydrogen production via water electrolysis faces a freshwater shortage.Direct seawater electrolysis offers a solution but encounters new challenges.Herein,we report a feasible strategy to both prevent metal hydroxides deposition and boost the hydrogen evolution reaction by adding a chelating agent,EDTA-Na_(4),that chelates with Mg^(2+)/Ca^(2+),thus inhibiting their deposition and gathering them near the cathode surface,resulting in breaking the ordered hydrogen bond networks of interfacial water and reducing the activation energy of water dissociation.Furthermore,hydrolysis of–COO^(-) also promoted water dissociation to produce more active*H and*OH near the electrode surface that in turn serves as a diffusion medium for*OH,accelerating mass transfer and enabling seawater electrolysis to exhibit a stable performance,which operates continuously at 100 mA cm^(-2)@2.20 V and 200 mA cm^(-2)@2.58 V for 400 h in the symmetric electrolyzer and 500 mA cm^(-2)@2.29 V for over 500 h in the asymmetric electrolyzer.This study provides a new perspective to address the issues of stable and scalable direct seawater electrolysis for practical green hydrogen production.
基金funded by 2023 Chongqing medical scientific research project(Joint project of Chongqing Health Commission and Science and Technology Bureaugrant no.2023GGXM006)+12 种基金oint project of Chongqing Health Commission and Science and Technology Bureau(Joint Key Laboratory Open Project)(No.2026KFXM051)Natural Science Foundation of Chongqing(No.CSTB2025NSCO-GPX1116)2026 Chongqing Municipal Health Commission Traditional Chinese Medicine Research Project(No.2026WSJK158),Technological Innovation Project of Shapingba District,Chongqing(No.2025016)2024 Scientific research project of Chongqing Medical and Pharmaceutical College(No.ygzrc2024101)Chongqing Municipal Education Commission Youth Project(No.KJQN202402821No.KJQN202502819)2024 Chongqing Medical and Pharmaceutical College Innovation Research Group Project(No.ygz2024401)Science and Health Joint Medical Research Project of Shapingba District,Chongqing(No.2024SQKWLHMS051)2025 Scientific research project of Chongqing Medical and Pharmaceutical College(No.YGZZK2025116)2025 Technological Innovation Project of Shapingba District,Chongqing(No.2025031)Chongqing Municipal Education Commission Youth Project(No.KJQN202402821No.KJQN202302811)Joint project of Chongqing Health Commission and Science and Technology Bureau(No.2024MSXM115)respectively.
文摘Host-yeast interactions are fundamental drivers of human microbiome dynamics,spanning a spectrum from mutualistic symbiosis to opportunistic pathogenesis with profound implications for systemic health.This review systematically elucidates the complex molecular mechanisms governing these relationships,with a specific focus on metabolic interdependence and immunomodulation.We analyze how yeast-derived metabolites,particularly short-chain fatty acids(SCFAs),modulate host glucose and lipid homeostasis via signaling pathways such as GPR41/43 and GLP-1 secretion.Furthermore,the review explores the pathophysiological role of fungal dysbiosis in chronic conditions,including obesity,diabetes,and inflammatory bowel disease(IBD),highlighting how a breakdown in host-yeast homeostasis triggers pro-inflammatory cascades.Beyond the fungal-host axis,we introduce the concept of the"mycobiome-virome-bacterial axis,"discussing how commensal yeasts synergize with beneficial bacteria like Bifidobacterium and influence viral infectivity through Interferon-mediated innate immune priming.We critically evaluate how cutting-edge technologies-including transgenic mouse models(specifically Dectin-1^(-/-)and CARD9^(-/-),metabolomics,and single-cell sequencing-have revolutionized our mechanistic understanding of these multi-kingdom dynamics.By integrating current findings,we identify critical knowledge gaps and propose high-resolution research frameworks,such as humanized organ-on-a-chip systems,to simulate intricate host-microbe interactions under physiological flow conditions.This comprehensive synthesis provides a strategic foundation for developing targeted,next-generation microbiome-based interventions to restore host-yeast balance and enhance overall human health.
文摘Abstract Problems in agricultural science and technology service system were ana- lyzed, such as system problem, investment and worker quality, and based on this countermeasures were proposed, so as to promote the development of modern agri- culture and construction of new countryside.
基金supported by the Special Edu-cational Research Budget(Research Promotion)[FY2009]the Special Budget(Project)[FY2010 and later years]from the Ministry of Education,Culture,Sports,Science and Technology(MEXT),Japansupported by the GRENE Arctic Climate Change Research Project,Japan
文摘To comprehensively understand the Arctic and Antarctic upper atmosphere, it is often crucial to analyze various data that are obtained from many regions. Infrastructure that promotes such interdisciplinary studies on the upper atmosphere has been developed by a Japanese inter-university project called the Inter-university Upper atmosphere Global Observation Network （1UGONET）. The objective of this paper is to describe the infrastructure and tools developed by IUGONET. We focus on the data analysis software. It is written in Interactive Data Language （IDL） and is a plug-in for the THEMIS Data Analysis Software suite （TDAS）, which is a set of IDL libraries used to visualize and analyze satellite- and ground-based data. We present plots of upper atmospheric data provided by IUGONET as examples of applications, and verify the usefulness of the software in the study of polar science. We discuss IUGONET＇s new and unique developments, i.e., an executable file of TDAS that can run on the IDL Virtual Machine, IDL routines to retrieve metadata from the IUGONET database, and an archive of 3-D simulation data that uses the Common Data Format so that it can easily be used with TDAS.
文摘The study based on radical constructivism seeks to identify Semester Two Accounting Courses students’ meaning of ogive. Data for this study include verbal and non-verbal information gathered from three students of Semester Two Accounting Courses in clinical interview sessions. The research participants have identified four processes performed on the basic elements to produce an ogive. In addition, five categories of products used by research participants to describe the ogive were identified.
