Sensors are considered as important elements of electronic devices.In many applications and service,Wireless Sensor Networks(WSNs)are involved in significant data sharing that are delivered to the sink node in energy ...Sensors are considered as important elements of electronic devices.In many applications and service,Wireless Sensor Networks(WSNs)are involved in significant data sharing that are delivered to the sink node in energy efficient man-ner using multi-hop communications.But,the major challenge in WSN is the nodes are having limited battery resources,it is important to monitor the consumption rate of energy is very much needed.However,reducing energy con-sumption can increase the network lifetime in effective manner.For that,clustering methods are widely used for optimizing the rate of energy consumption among the sensor nodes.In that concern,this paper involves in deriving a novel model called Improved Load-Balanced Clustering for Energy-Aware Routing(ILBC-EAR),which mainly concentrates on optimal energy utilization with load-balanced process among cluster heads and member nodes.For providing equal rate of energy consumption among nodes,the dimensions of framed clusters are measured.Moreover,the model develops a Finest Routing Scheme based on Load-Balanced Clustering to transmit the sensed information to the sink or base station.The evaluation results depict that the derived energy aware model attains higher rate of life time than other works and also achieves balanced energy rate among head node.Additionally,the model also provides higher throughput and minimal delay in delivering data packets.展开更多
Based on the Smit-Suhl formula,we propose a universal approach for solving the magnon-magnon coupling problem in bilayer coupled systems(e.g.,antiferromagnets).This method requires only the energy expression,enabling ...Based on the Smit-Suhl formula,we propose a universal approach for solving the magnon-magnon coupling problem in bilayer coupled systems(e.g.,antiferromagnets).This method requires only the energy expression,enabling the automatic derivation of analytical expressions for the eigenmatrix elements via symbolic computation,eliminating the need for tedious manual calculations.Using this approach,we investigate the impact of magnetic hysteresis on magnon-magnon coupling in a system with interlayer Dzyaloshinskii-Moriya interaction(DMI).The magnetic hysteresis leads to an asymmetric magnetic field dependence of the resonance frequency and alters the number of degeneracy points between the pure optical and acoustic modes.Moreover,it can result in the coupling strength at the gap of the f–H phase diagram being nearly vanishing,contrary to the conventionally expected maximum.These results deepen the understanding of the effect of interlayer DMI on magnon–magnon coupling and the proposed universal method significantly streamlines the solving process of magnon–magnon coupling problems.展开更多
Background Exogenous xylanase can increase utilization of fiber and energy when included in diets for pigs,and xylo-oligosaccharides(XOS)may improve growth performance of pigs by modulating intestinal fermentation.How...Background Exogenous xylanase can increase utilization of fiber and energy when included in diets for pigs,and xylo-oligosaccharides(XOS)may improve growth performance of pigs by modulating intestinal fermentation.However,it is unclear if a stimbiotic(i.e.,a combination of xylanase and XOS)has superior effects compared with a xylanase alone,and there is a lack of data demonstrating if xylanase fed to lactating sows influences growth performance of weanling pigs.Therefore,two hypotheses were tested:1)xylanase and stimbiotic improve growth performance,apparent total tract digestibility(ATTD)of gross energy(GE)and total dietary fiber(TDF),digestible energy(DE),and intestinal health of weanling pigs and 2)offspring of sows fed xylanase in lactation have greater growth performance after weaning than offspring of sows fed no xylanase during lactation.Methods One hundred and twenty pigs were weaned from sows fed a diet without xylanase,and 120 pigs were weaned from sows fed a lactation diet containing 16,000 beechwood xylanase units per kg(initial weight:5.81±0.50 kg).Pigs were allotted to a 2×3 factorial with two sow groups(lactation diet without or with xylanase)and three dietary treatments(i.e.,control,control plus xylanase,or control plus stimbiotic).Results There were no interactions between sow treatment and post-weaning pig treatment,and sow treatment did not impact post-weaning growth or ATTD of GE and TDF in weaned pigs.From d 15 to 28 post-weaning,the ADG,G:F,ATTD of GE and TDF,and concentration of DE were greater(P<0.05)for pigs fed the diet with stimbiotic than if fed the xylanase diet or the control diet,and pigs fed the xylanase diet had greater(P<0.05)ADG,G:F,ATTD of GE and TDF,and concentration of DE than pigs fed the control diet.From d 29 to 42 post-weaning,pigs fed the diets with xylanase or stimbiotic had greater(P<0.05)ADG,ATTD of GE and TDF,and DE than pigs fed the control diet.Conclusions Pigs fed xylanase or stimbiotic had greater ATTD of GE and TDF,greater DE,and greater overall ADG,G:F,and final body weight on d 42 post-weaning than pigs fed the control diet,but feeding sows xylanase in lactation did not influence post-weaning growth performance.展开更多
Objective To investigate hypertension(HTN)trends,key risk factors,and gender disparities in rural China,and to propose targeted strategies for improving HTN control in resource-limited settings.Methods This longitudin...Objective To investigate hypertension(HTN)trends,key risk factors,and gender disparities in rural China,and to propose targeted strategies for improving HTN control in resource-limited settings.Methods This longitudinal study used data from the Henan Rural Cohort Study,including baseline(2015–2017;n=39,224)and follow-up(2018–2022;n=28,621)participants.HTN was defined as systolic/diastolic blood pressure≥140/90 mmHg,self-reported diagnosis,or use of antihypertensive medication.Severity was classified using a 7-tier blood pressure(BP)staging system(optimal,normal,high normal,and HTN stages 1–4).A generalized linear mixed-effects model(GLMM)identified associated risk factors.Results HTN prevalence increased modestly from 32.7%(95%CI:32.2–33.2)to 33.9%(95%CI:33.3%–34.4%).Awareness and treatment improved from 20.1%to 25.3%,and from 18.8%to 24.4%,respectively,but control rates remained low(6.2%to 12.3%).After adjustment,women had a 1.53-fold higher HTN risk than men(OR=1.53,95%CI:1.43–1.63),revealing gender-specific trends.Key risk factors included alcohol use(OR=1.37,95%CI:1.27–1.47)and overweight status(OR=1.76,95%CI:1.66–1.86).BP staging showed an increase in optimal BP(42.3%to 45.8%),but stagnant management of advanced HTN stages.Conclusion Hypertension in rural China is shaped by behavioral risk factors and healthcare access gaps.Gender-sensitive,community-based interventions,including task-shifting models,are necessary to mitigate the growing burden of hypertension.展开更多
Impinging jet arrays are extensively used in numerous industrial operations,including the cooling of electronics,turbine blades,and other high-heat flux systems because of their superior heat transfer capabilities.Opt...Impinging jet arrays are extensively used in numerous industrial operations,including the cooling of electronics,turbine blades,and other high-heat flux systems because of their superior heat transfer capabilities.Optimizing the design and operating parameters of such systems is essential to enhance cooling efficiency and achieve uniform pressure distribution,which can lead to improved system performance and energy savings.This paper presents two multi-objective optimization methodologies for a turbulent air jet impingement cooling system.The governing equations are resolved employing the commercial computational fluid dynamics(CFD)software ANSYS Fluent v17.The study focuses on four controlling parameters:Reynolds number(Re),swirl number(S),jet-to-jet separation distance(Z/D),and impingement height(H/D).The effects of these parameters on heat transfer and impingement pressure distribution are investigated.Non-dominated Sorting Genetic Algorithm(NSGA-II)and Weighted Sum Method(WSM)are employed to optimize the controlling parameters for maximum cooling performance.The aim is to identify optimal design parameters and system configurations that enhance heat transfer efficiency while achieving a uniform impingement pressure distribution.These findings have practical implications for applications requiring efficient cooling.The optimized design achieved a 12.28%increase in convective heat transfer efficiency with a local Nusselt number of 113.05 compared to 100.69 in the reference design.Enhanced convective cooling and heat flux were observed in the optimized configuration,particularly in areas of direct jet impingement.Additionally,the optimized design maintained lower wall temperatures,demonstrating more effective thermal dissipation.展开更多
Cloud forests are unusual and fragile habitats, being one of the least studied and least understood ecosystems. The tropical Andean dominion is considered one of the most significant places in the world as regards bio...Cloud forests are unusual and fragile habitats, being one of the least studied and least understood ecosystems. The tropical Andean dominion is considered one of the most significant places in the world as regards biological diversity, with a very high level of endemism. The biodiversity was analysed in an isolated remnant area of a tropical montane cloud forest known as the "Bosque de Neblina de Cuyas", in the North of the Peruvian Andean range. Composition, structure and dead wood were measured or estimated. The values obtained were compared with other cloud forests. The study revealed a high level of forest biodiversity, although the level of biodiversity differs from one area to another: in the inner areas, where human pressure is almost inexistent, the biodiversity values increase. The high species richness and the low dominance among species bear testimony to this montane cloud forest as a real enclave of biodiversity.展开更多
The present research deals with development and characterisation of magnesium–SiC–Gr hybrid composites through powder metallurgy route.Morphology analysis of the magnesium and reinforcement powder particles has been...The present research deals with development and characterisation of magnesium–SiC–Gr hybrid composites through powder metallurgy route.Morphology analysis of the magnesium and reinforcement powder particles has been carried out using particle size analyser(PSA)and X-ray diffraction(XRD),and then the mixed powders were analysed through scanning electron microscope(SEM).The developed composite exhibit increased hardness when compared to base material,which could be attributed to the presence of hard SiC.Furthermore,a slight decrease in hardness is observed for the hybrid composite when compared to Mg–SiC composite due to the presence of soft Gr particles.The tribological properties of the developed composite materials were investigated using pin-on-disc wear test apparatus under dry sliding conditions.The wear resistance of the developed composites improved significantly than that of the magnesium matrix due to the upright effect offered by both of the reinforcements.The SEM analysis was carried out on the worn out surfaces for better understanding of wear mechanisms.5%Gr reinforced Mg-10SiC composites confer better wear resistance among the developed composites.展开更多
Probiotic bacteria have well-established beneficial ef-fects in the management of diarrhoeal diseases.Newer evidence suggests that probiotics have the potential to reduce the risk of developing inflammatory bowel dise...Probiotic bacteria have well-established beneficial ef-fects in the management of diarrhoeal diseases.Newer evidence suggests that probiotics have the potential to reduce the risk of developing inflammatory bowel diseases and intestinal bacterial overgrowth after gut surgery.In liver health,the main benefits of probiotics might occur through preventing the production and/or uptake of lipopolysaccharides in the gut,and therefore reducing levels of low-grade inflammation.Specific immune stimulation by probiotics through processes involving dendritic cells might also be beneficial to the host immunological status and help prevent pathogen translocation.Hepatic fat metabolism also seems to be influenced by the presence of commensal bacteria,and potentially by probiotics;although the mechanisms by which probiotic might act on the liver are still unclear.However,this might be of major importance in the fu-ture because low-grade inflammation,hepatic fat infil-tration,and hepatitis might become more prevalent as a result of high fat intake and the increased prevalence of obesity.展开更多
Objective:To evaluate coagulation abnormalities and their relationship with bleeding manifestations among patients with dengue.Methods:This observational study was conducted on 292 adult dengue patients who were admit...Objective:To evaluate coagulation abnormalities and their relationship with bleeding manifestations among patients with dengue.Methods:This observational study was conducted on 292 adult dengue patients who were admitted to a tertiary care hospital of Western India from July 2021 to June 2022.Coagulation tests including prothrombin time(PT),international normalized ratio(INR),activated partial thromboplastin time(aPTT),fibrinogen,and D-dimer were performed.Patients were monitored for bleeding manifestations.Results:Coagulation abnormalities were reported in 42.8%of the patients.Overall,prolonged aPTT was the most common coagulation abnormality(40.8%),followed by low fibrinogen(38.7%),raised D-dimer(31.2%),raised INR(26.0%)and prolonged PT(19.2%).Bleeding manifestations were present in 19.9%patients.PT,INR,aPTT and D-dimer levels were significantly higher(P<0.01)and fibrinogen level was significantly lower(P<0.001)in patients with bleeding compared to patients without bleeding.Patients with bleeding had a significantly higher rate of all coagulation abnormalities than patients without bleeding(P<0.01).Conclusions:Patients with bleeding showed a significantly higher frequency of coagulation abnormalities compared to patients without bleeding.Patients with dengue should be assessed for coagulation abnormalities.展开更多
This paper gives a succinct review of dual-spinprojectile stability and some technologies relating to them.It describes how the traditional stability factors from linear projectile theory are modified to better descri...This paper gives a succinct review of dual-spinprojectile stability and some technologies relating to them.It describes how the traditional stability factors from linear projectile theory are modified to better describe a controlled dual-spin projectile.Finally,it reviews works which have investigated how different aspects of a controlled dual-spin design can affect flight stability,primarily airframe structure and canard properties.A conclusion is given,highlighting important guidelines from the enclosed discussions.展开更多
A Machine Learning (ML)-based Intrusion Detection and Prevention System (IDPS)requires a large amount of labeled up-to-date training data to effectively detect intrusions and generalize well to novel attacks.However,t...A Machine Learning (ML)-based Intrusion Detection and Prevention System (IDPS)requires a large amount of labeled up-to-date training data to effectively detect intrusions and generalize well to novel attacks.However,the labeling of data is costly and becomes infeasible when dealing with big data,such as those generated by Intemet of Things applications.To this effect,building an ML model that learns from non-labeled or partially labeled data is of critical importance.This paper proposes a Semi-supervised Mniti-Layered Clustering ((SMLC))model for the detection and prevention of network intrusion.SMLC has the capability to learn from partially labeled data while achieving a detection performance comparable to that of supervised ML-based IDPS.The performance of SMLC is compared with that of a well-known semi-supervised model (tri-training)and of supervised ensemble ML models, namely Random.Forest,Bagging,and AdaboostM1on two benchmark network-intrusion datasets,NSL and Kyoto 2006+.Experimental resnits show that SMLC is superior to tri-training,providing a comparable detection accuracy with 20%less labeled instances of training data.Furthermore,our results demonstrate that our scheme has a detection accuracy comparable to that of the supervised ensemble models.展开更多
Phytomediated synthesis of metal oxide nanoparticles has become a key research area in nanotechnology due to its wide applicability in various biomedical fields. The present work explores the biosynthesis of zinc oxid...Phytomediated synthesis of metal oxide nanoparticles has become a key research area in nanotechnology due to its wide applicability in various biomedical fields. The present work explores the biosynthesis of zinc oxide nanoparticles（ZnO-NPs） using Leucaena leucocephala leaf extract. The synthesised ZnO-NPs were characterised by ultraviolet-visible（UV-Vis） spectroscopy, scanning electron microscopy（SEM）, energydispersive X-ray spectroscopy（EDX）, Fourier transform infrared spectroscopy（FTIR）, X-ray diffraction（XRD）,transmission electron microscopy（TEM） and selected area electron diffraction（SAED） studies. Biosynthesised ZnONPs are found to have wurtzite hexagonal structure with particles distributed in the range of 50-200 nm as confirmed by TEM studies. The anticancer activity of ZnONPs against MCF-7（breast cancer） and PC-3（human prostate cancer） cell lines was evaluated using 3-（4,5-dimethylthiazol-2-yl）-2,5-diphenyltetrazolium bromide（MTT） assay. From the assay, biosynthesised ZnO-NPs have better cytotoxic activity on PC-3 cell lines than MCF-7 cell lines. The in vitro cytotoxicity studies of biosynthesised ZnO-NPs against Dalton lymphoma ascites（DLA）cells reveal better antitumor activity of 92% inhibition with concentration of 200 μg·ml-1 of ZnO-NPs,and as the concentration increases, the anticancer efficiency as well increases, and also, it has excellent photocatalytic activity to degrade crystal violet dye in aqueous solution after irradiation of 90 min. The result suggests that the green synthesis of ZnO-NPs could be easily recovered and reused several times without any significant loss of the catalytic activity. The advantage of this technique lies in its low cost, easily climb able and non-use of toxic agents.展开更多
文摘Sensors are considered as important elements of electronic devices.In many applications and service,Wireless Sensor Networks(WSNs)are involved in significant data sharing that are delivered to the sink node in energy efficient man-ner using multi-hop communications.But,the major challenge in WSN is the nodes are having limited battery resources,it is important to monitor the consumption rate of energy is very much needed.However,reducing energy con-sumption can increase the network lifetime in effective manner.For that,clustering methods are widely used for optimizing the rate of energy consumption among the sensor nodes.In that concern,this paper involves in deriving a novel model called Improved Load-Balanced Clustering for Energy-Aware Routing(ILBC-EAR),which mainly concentrates on optimal energy utilization with load-balanced process among cluster heads and member nodes.For providing equal rate of energy consumption among nodes,the dimensions of framed clusters are measured.Moreover,the model develops a Finest Routing Scheme based on Load-Balanced Clustering to transmit the sensed information to the sink or base station.The evaluation results depict that the derived energy aware model attains higher rate of life time than other works and also achieves balanced energy rate among head node.Additionally,the model also provides higher throughput and minimal delay in delivering data packets.
基金supported by the National Key Research and Development Program of China (MOST)(Grant No.2022YFA1402800)the Chinese Academy of Sciences (CAS) Presidents International Fellowship Initiative (PIFI)(Grant No.2025PG0006)+3 种基金the National Natural Science Foundation of China (NSFC)(Grant Nos.51831012,12274437,and 52161160334)the CAS Project for Young Scientists in Basic Research (Grant No.YSBR-084)the CAS Youth Interdisciplinary Teamthe China Postdoctoral Science Foundation (Grant No.2025M773402)。
文摘Based on the Smit-Suhl formula,we propose a universal approach for solving the magnon-magnon coupling problem in bilayer coupled systems(e.g.,antiferromagnets).This method requires only the energy expression,enabling the automatic derivation of analytical expressions for the eigenmatrix elements via symbolic computation,eliminating the need for tedious manual calculations.Using this approach,we investigate the impact of magnetic hysteresis on magnon-magnon coupling in a system with interlayer Dzyaloshinskii-Moriya interaction(DMI).The magnetic hysteresis leads to an asymmetric magnetic field dependence of the resonance frequency and alters the number of degeneracy points between the pure optical and acoustic modes.Moreover,it can result in the coupling strength at the gap of the f–H phase diagram being nearly vanishing,contrary to the conventionally expected maximum.These results deepen the understanding of the effect of interlayer DMI on magnon–magnon coupling and the proposed universal method significantly streamlines the solving process of magnon–magnon coupling problems.
基金financial support for this research by AB Vista,Marlborough,UK,is greatly appreciated.
文摘Background Exogenous xylanase can increase utilization of fiber and energy when included in diets for pigs,and xylo-oligosaccharides(XOS)may improve growth performance of pigs by modulating intestinal fermentation.However,it is unclear if a stimbiotic(i.e.,a combination of xylanase and XOS)has superior effects compared with a xylanase alone,and there is a lack of data demonstrating if xylanase fed to lactating sows influences growth performance of weanling pigs.Therefore,two hypotheses were tested:1)xylanase and stimbiotic improve growth performance,apparent total tract digestibility(ATTD)of gross energy(GE)and total dietary fiber(TDF),digestible energy(DE),and intestinal health of weanling pigs and 2)offspring of sows fed xylanase in lactation have greater growth performance after weaning than offspring of sows fed no xylanase during lactation.Methods One hundred and twenty pigs were weaned from sows fed a diet without xylanase,and 120 pigs were weaned from sows fed a lactation diet containing 16,000 beechwood xylanase units per kg(initial weight:5.81±0.50 kg).Pigs were allotted to a 2×3 factorial with two sow groups(lactation diet without or with xylanase)and three dietary treatments(i.e.,control,control plus xylanase,or control plus stimbiotic).Results There were no interactions between sow treatment and post-weaning pig treatment,and sow treatment did not impact post-weaning growth or ATTD of GE and TDF in weaned pigs.From d 15 to 28 post-weaning,the ADG,G:F,ATTD of GE and TDF,and concentration of DE were greater(P<0.05)for pigs fed the diet with stimbiotic than if fed the xylanase diet or the control diet,and pigs fed the xylanase diet had greater(P<0.05)ADG,G:F,ATTD of GE and TDF,and concentration of DE than pigs fed the control diet.From d 29 to 42 post-weaning,pigs fed the diets with xylanase or stimbiotic had greater(P<0.05)ADG,ATTD of GE and TDF,and DE than pigs fed the control diet.Conclusions Pigs fed xylanase or stimbiotic had greater ATTD of GE and TDF,greater DE,and greater overall ADG,G:F,and final body weight on d 42 post-weaning than pigs fed the control diet,but feeding sows xylanase in lactation did not influence post-weaning growth performance.
基金supported by the National Natural Science Foundation of China(Grant NO:81930092 and 81973128)Natural Science Foundation of Henan Province(Grant NO:23230042151)+1 种基金Science and Technology Innovation Team Support Plan of Colleges and Universities in Henan Province(Grant NO:21IRTSTHN029)the Foundation of National Key Program of Research and Development of China(Grant No:2016YFC0900803).
文摘Objective To investigate hypertension(HTN)trends,key risk factors,and gender disparities in rural China,and to propose targeted strategies for improving HTN control in resource-limited settings.Methods This longitudinal study used data from the Henan Rural Cohort Study,including baseline(2015–2017;n=39,224)and follow-up(2018–2022;n=28,621)participants.HTN was defined as systolic/diastolic blood pressure≥140/90 mmHg,self-reported diagnosis,or use of antihypertensive medication.Severity was classified using a 7-tier blood pressure(BP)staging system(optimal,normal,high normal,and HTN stages 1–4).A generalized linear mixed-effects model(GLMM)identified associated risk factors.Results HTN prevalence increased modestly from 32.7%(95%CI:32.2–33.2)to 33.9%(95%CI:33.3%–34.4%).Awareness and treatment improved from 20.1%to 25.3%,and from 18.8%to 24.4%,respectively,but control rates remained low(6.2%to 12.3%).After adjustment,women had a 1.53-fold higher HTN risk than men(OR=1.53,95%CI:1.43–1.63),revealing gender-specific trends.Key risk factors included alcohol use(OR=1.37,95%CI:1.27–1.47)and overweight status(OR=1.76,95%CI:1.66–1.86).BP staging showed an increase in optimal BP(42.3%to 45.8%),but stagnant management of advanced HTN stages.Conclusion Hypertension in rural China is shaped by behavioral risk factors and healthcare access gaps.Gender-sensitive,community-based interventions,including task-shifting models,are necessary to mitigate the growing burden of hypertension.
文摘Impinging jet arrays are extensively used in numerous industrial operations,including the cooling of electronics,turbine blades,and other high-heat flux systems because of their superior heat transfer capabilities.Optimizing the design and operating parameters of such systems is essential to enhance cooling efficiency and achieve uniform pressure distribution,which can lead to improved system performance and energy savings.This paper presents two multi-objective optimization methodologies for a turbulent air jet impingement cooling system.The governing equations are resolved employing the commercial computational fluid dynamics(CFD)software ANSYS Fluent v17.The study focuses on four controlling parameters:Reynolds number(Re),swirl number(S),jet-to-jet separation distance(Z/D),and impingement height(H/D).The effects of these parameters on heat transfer and impingement pressure distribution are investigated.Non-dominated Sorting Genetic Algorithm(NSGA-II)and Weighted Sum Method(WSM)are employed to optimize the controlling parameters for maximum cooling performance.The aim is to identify optimal design parameters and system configurations that enhance heat transfer efficiency while achieving a uniform impingement pressure distribution.These findings have practical implications for applications requiring efficient cooling.The optimized design achieved a 12.28%increase in convective heat transfer efficiency with a local Nusselt number of 113.05 compared to 100.69 in the reference design.Enhanced convective cooling and heat flux were observed in the optimized configuration,particularly in areas of direct jet impingement.Additionally,the optimized design maintained lower wall temperatures,demonstrating more effective thermal dissipation.
基金supported by Nature and Culture International (NCI-Perú) and partially funded through a Grant from the Universidad Politécnica de Madrid
文摘Cloud forests are unusual and fragile habitats, being one of the least studied and least understood ecosystems. The tropical Andean dominion is considered one of the most significant places in the world as regards biological diversity, with a very high level of endemism. The biodiversity was analysed in an isolated remnant area of a tropical montane cloud forest known as the "Bosque de Neblina de Cuyas", in the North of the Peruvian Andean range. Composition, structure and dead wood were measured or estimated. The values obtained were compared with other cloud forests. The study revealed a high level of forest biodiversity, although the level of biodiversity differs from one area to another: in the inner areas, where human pressure is almost inexistent, the biodiversity values increase. The high species richness and the low dominance among species bear testimony to this montane cloud forest as a real enclave of biodiversity.
文摘The present research deals with development and characterisation of magnesium–SiC–Gr hybrid composites through powder metallurgy route.Morphology analysis of the magnesium and reinforcement powder particles has been carried out using particle size analyser(PSA)and X-ray diffraction(XRD),and then the mixed powders were analysed through scanning electron microscope(SEM).The developed composite exhibit increased hardness when compared to base material,which could be attributed to the presence of hard SiC.Furthermore,a slight decrease in hardness is observed for the hybrid composite when compared to Mg–SiC composite due to the presence of soft Gr particles.The tribological properties of the developed composite materials were investigated using pin-on-disc wear test apparatus under dry sliding conditions.The wear resistance of the developed composites improved significantly than that of the magnesium matrix due to the upright effect offered by both of the reinforcements.The SEM analysis was carried out on the worn out surfaces for better understanding of wear mechanisms.5%Gr reinforced Mg-10SiC composites confer better wear resistance among the developed composites.
文摘Probiotic bacteria have well-established beneficial ef-fects in the management of diarrhoeal diseases.Newer evidence suggests that probiotics have the potential to reduce the risk of developing inflammatory bowel diseases and intestinal bacterial overgrowth after gut surgery.In liver health,the main benefits of probiotics might occur through preventing the production and/or uptake of lipopolysaccharides in the gut,and therefore reducing levels of low-grade inflammation.Specific immune stimulation by probiotics through processes involving dendritic cells might also be beneficial to the host immunological status and help prevent pathogen translocation.Hepatic fat metabolism also seems to be influenced by the presence of commensal bacteria,and potentially by probiotics;although the mechanisms by which probiotic might act on the liver are still unclear.However,this might be of major importance in the fu-ture because low-grade inflammation,hepatic fat infil-tration,and hepatitis might become more prevalent as a result of high fat intake and the increased prevalence of obesity.
文摘Objective:To evaluate coagulation abnormalities and their relationship with bleeding manifestations among patients with dengue.Methods:This observational study was conducted on 292 adult dengue patients who were admitted to a tertiary care hospital of Western India from July 2021 to June 2022.Coagulation tests including prothrombin time(PT),international normalized ratio(INR),activated partial thromboplastin time(aPTT),fibrinogen,and D-dimer were performed.Patients were monitored for bleeding manifestations.Results:Coagulation abnormalities were reported in 42.8%of the patients.Overall,prolonged aPTT was the most common coagulation abnormality(40.8%),followed by low fibrinogen(38.7%),raised D-dimer(31.2%),raised INR(26.0%)and prolonged PT(19.2%).Bleeding manifestations were present in 19.9%patients.PT,INR,aPTT and D-dimer levels were significantly higher(P<0.01)and fibrinogen level was significantly lower(P<0.001)in patients with bleeding compared to patients without bleeding.Patients with bleeding had a significantly higher rate of all coagulation abnormalities than patients without bleeding(P<0.01).Conclusions:Patients with bleeding showed a significantly higher frequency of coagulation abnormalities compared to patients without bleeding.Patients with dengue should be assessed for coagulation abnormalities.
基金sponsored by EPSRC ICASE Grant reference 1700064BAE Systems。
文摘This paper gives a succinct review of dual-spinprojectile stability and some technologies relating to them.It describes how the traditional stability factors from linear projectile theory are modified to better describe a controlled dual-spin projectile.Finally,it reviews works which have investigated how different aspects of a controlled dual-spin design can affect flight stability,primarily airframe structure and canard properties.A conclusion is given,highlighting important guidelines from the enclosed discussions.
文摘A Machine Learning (ML)-based Intrusion Detection and Prevention System (IDPS)requires a large amount of labeled up-to-date training data to effectively detect intrusions and generalize well to novel attacks.However,the labeling of data is costly and becomes infeasible when dealing with big data,such as those generated by Intemet of Things applications.To this effect,building an ML model that learns from non-labeled or partially labeled data is of critical importance.This paper proposes a Semi-supervised Mniti-Layered Clustering ((SMLC))model for the detection and prevention of network intrusion.SMLC has the capability to learn from partially labeled data while achieving a detection performance comparable to that of supervised ML-based IDPS.The performance of SMLC is compared with that of a well-known semi-supervised model (tri-training)and of supervised ensemble ML models, namely Random.Forest,Bagging,and AdaboostM1on two benchmark network-intrusion datasets,NSL and Kyoto 2006+.Experimental resnits show that SMLC is superior to tri-training,providing a comparable detection accuracy with 20%less labeled instances of training data.Furthermore,our results demonstrate that our scheme has a detection accuracy comparable to that of the supervised ensemble models.
文摘Phytomediated synthesis of metal oxide nanoparticles has become a key research area in nanotechnology due to its wide applicability in various biomedical fields. The present work explores the biosynthesis of zinc oxide nanoparticles（ZnO-NPs） using Leucaena leucocephala leaf extract. The synthesised ZnO-NPs were characterised by ultraviolet-visible（UV-Vis） spectroscopy, scanning electron microscopy（SEM）, energydispersive X-ray spectroscopy（EDX）, Fourier transform infrared spectroscopy（FTIR）, X-ray diffraction（XRD）,transmission electron microscopy（TEM） and selected area electron diffraction（SAED） studies. Biosynthesised ZnONPs are found to have wurtzite hexagonal structure with particles distributed in the range of 50-200 nm as confirmed by TEM studies. The anticancer activity of ZnONPs against MCF-7（breast cancer） and PC-3（human prostate cancer） cell lines was evaluated using 3-（4,5-dimethylthiazol-2-yl）-2,5-diphenyltetrazolium bromide（MTT） assay. From the assay, biosynthesised ZnO-NPs have better cytotoxic activity on PC-3 cell lines than MCF-7 cell lines. The in vitro cytotoxicity studies of biosynthesised ZnO-NPs against Dalton lymphoma ascites（DLA）cells reveal better antitumor activity of 92% inhibition with concentration of 200 μg·ml-1 of ZnO-NPs,and as the concentration increases, the anticancer efficiency as well increases, and also, it has excellent photocatalytic activity to degrade crystal violet dye in aqueous solution after irradiation of 90 min. The result suggests that the green synthesis of ZnO-NPs could be easily recovered and reused several times without any significant loss of the catalytic activity. The advantage of this technique lies in its low cost, easily climb able and non-use of toxic agents.
