This paper proposes the first code-based quantum immune sequential aggregate signature(SAS)scheme and proves the security of the proposed scheme in the random oracle model.Aggregate signature(AS)schemes and sequential...This paper proposes the first code-based quantum immune sequential aggregate signature(SAS)scheme and proves the security of the proposed scheme in the random oracle model.Aggregate signature(AS)schemes and sequential aggregate signature schemes allow a group of potential signers to sign different messages respectively,and all the signatures of those users on those messages can be aggregated into a single signature such that the size of the aggregate signature is much smaller than the total size of all individual signatures.Because of the aggregation of many signatures into a single short signature,AS and SAS schemes can reduce bandwidth and save storage;moreover,when a SAS is verified,not only the valid but also the order in which each signer signed can be verified.AS and SAS schemes can be applied to traffic control,banking transaction and military applications.Most of the existing AS and SAS schemes are based either on pairing or Rivest-Shamir-Adleman(RSA),and hence,can be broken by Shor’s quantum algorithm for Integer Factoring Problem(IFP)and Discrete Logarithm Problem(DLP).There are no quantum algorithms to solve syndrome decoding problems.Hence,code-based cryptography is seen as one of the promising candidates for post-quantum cryptography.This paper shows how to construct quantum immune sequential aggregate signatures based on coding theory.Specifically,we construct our scheme with the first code based signature scheme proposed by Courtois,Finiasz and Sendrier(CFS).Compared to the CFS signature scheme without aggregation,the proposed sequential aggregate signature scheme can save about 90%storage when the number of signers is asymptotically large.展开更多
Highly stable hydrophobic silica-based membranes were successfully fabricated through chemical post-modification of directly electrospun silica nanofibrous membranes.Five different Si-alkoxy chlorides were tried as re...Highly stable hydrophobic silica-based membranes were successfully fabricated through chemical post-modification of directly electrospun silica nanofibrous membranes.Five different Si-alkoxy chlorides were tried as reagents at room temperature,allowing for an easy two-step production process.Trimethylchlorosilane(TMCS)was determined as to be the most suitable modifier,for this purpose.The modified membrane exhibits long-term hydrophobicity even under high humidity and water submersion,maintaining this property after exposure to elevated temperatures and acidic conditions,surpassing the unmodified membrane.The separation effectiveness for immiscible water/solvent solutions was proven,followed by an investigation into the relation between the surface tension of some miscible water/solvent solutions and the resulting wetting behavior of the TMCS-modified membrane,to utilize the membrane as a process intensification tool,specifically as a solvent gate.展开更多
Nucleic acid sensing is a 3 decades old but still challenging area of application for different biological sub-domains,from pathogen detection to single cell transcriptomics analysis.The many applications of nucleic a...Nucleic acid sensing is a 3 decades old but still challenging area of application for different biological sub-domains,from pathogen detection to single cell transcriptomics analysis.The many applications of nucleic acid detection and identification are mostly carried out by PCR techniques,sequencing,and their derivatives used at large scale.However,these methods’limitations on speed,cost,complexity and specificity have motivated the development of innovative detection methods among which nucleic acid biosensing technologies seem promising.Toehold switches are a particular class of RNA sensing devices relying on a conformational switch of secondary structure induced by the pairing of the detected trigger RNA with a de novo designed synthetic sensing mRNA molecule.Here we describe a streamlined methodology enabling the development of such a sensor for the RNA-mediated detection of an endangered plant species in a cell-free reaction system.We applied this methodology to help identify the rosewood Dalbergia maritima,a highly trafficked wood,whose protection is limited by the capacity of the authorities to distinguish protected logs from other unprotected but related species.The streamlined pipeline presented in this work is a versatile framework enabling cheap and rapid development of new sensors for custom RNA detection.展开更多
基金This work was supported in part by the National Natural Science Foundation of China under Grant 62072240by the Natural Science Foundation of Jiangsu Province under Grant BK20210330by the National Key Research and Development Program of China under Grant 2020YFB1804604.
文摘This paper proposes the first code-based quantum immune sequential aggregate signature(SAS)scheme and proves the security of the proposed scheme in the random oracle model.Aggregate signature(AS)schemes and sequential aggregate signature schemes allow a group of potential signers to sign different messages respectively,and all the signatures of those users on those messages can be aggregated into a single signature such that the size of the aggregate signature is much smaller than the total size of all individual signatures.Because of the aggregation of many signatures into a single short signature,AS and SAS schemes can reduce bandwidth and save storage;moreover,when a SAS is verified,not only the valid but also the order in which each signer signed can be verified.AS and SAS schemes can be applied to traffic control,banking transaction and military applications.Most of the existing AS and SAS schemes are based either on pairing or Rivest-Shamir-Adleman(RSA),and hence,can be broken by Shor’s quantum algorithm for Integer Factoring Problem(IFP)and Discrete Logarithm Problem(DLP).There are no quantum algorithms to solve syndrome decoding problems.Hence,code-based cryptography is seen as one of the promising candidates for post-quantum cryptography.This paper shows how to construct quantum immune sequential aggregate signatures based on coding theory.Specifically,we construct our scheme with the first code based signature scheme proposed by Courtois,Finiasz and Sendrier(CFS).Compared to the CFS signature scheme without aggregation,the proposed sequential aggregate signature scheme can save about 90%storage when the number of signers is asymptotically large.
基金funding from the China Scholarship Council(Grant No.201608230115)for the Ph.D.study at Ghent UniversityThis Research Foundation Flanders(FWO)is gratefully acknowledged by E.L.for funding the research through an SB PhD grant under Grant No.1S82920N+1 种基金The authors would like to thank the NMR expertise centre(Ghent University)for providing support and access to its NMR infrastructureThe 300 MHz used in this work has been funded by grants from the FWO.K.D.C.thanks the Special Research Fund Ghent University(BOF)for the grants BOF.BAS.2018.0015.01 and BOF19/24J/102.
文摘Highly stable hydrophobic silica-based membranes were successfully fabricated through chemical post-modification of directly electrospun silica nanofibrous membranes.Five different Si-alkoxy chlorides were tried as reagents at room temperature,allowing for an easy two-step production process.Trimethylchlorosilane(TMCS)was determined as to be the most suitable modifier,for this purpose.The modified membrane exhibits long-term hydrophobicity even under high humidity and water submersion,maintaining this property after exposure to elevated temperatures and acidic conditions,surpassing the unmodified membrane.The separation effectiveness for immiscible water/solvent solutions was proven,followed by an investigation into the relation between the surface tension of some miscible water/solvent solutions and the resulting wetting behavior of the TMCS-modified membrane,to utilize the membrane as a process intensification tool,specifically as a solvent gate.
文摘Nucleic acid sensing is a 3 decades old but still challenging area of application for different biological sub-domains,from pathogen detection to single cell transcriptomics analysis.The many applications of nucleic acid detection and identification are mostly carried out by PCR techniques,sequencing,and their derivatives used at large scale.However,these methods’limitations on speed,cost,complexity and specificity have motivated the development of innovative detection methods among which nucleic acid biosensing technologies seem promising.Toehold switches are a particular class of RNA sensing devices relying on a conformational switch of secondary structure induced by the pairing of the detected trigger RNA with a de novo designed synthetic sensing mRNA molecule.Here we describe a streamlined methodology enabling the development of such a sensor for the RNA-mediated detection of an endangered plant species in a cell-free reaction system.We applied this methodology to help identify the rosewood Dalbergia maritima,a highly trafficked wood,whose protection is limited by the capacity of the authorities to distinguish protected logs from other unprotected but related species.The streamlined pipeline presented in this work is a versatile framework enabling cheap and rapid development of new sensors for custom RNA detection.
