Obstructive Sleep Apnea Syndrome (OSAS) is a respiratory sleep disorder characterized by repeated episodes of complete or partial obstruction of the upper airway. OSAS has a frequency of 4 percent and is classified ac...Obstructive Sleep Apnea Syndrome (OSAS) is a respiratory sleep disorder characterized by repeated episodes of complete or partial obstruction of the upper airway. OSAS has a frequency of 4 percent and is classified according to the number of obstructive sleep apnea-hypopnea episodes. The OSAS diagnostic path starts with the evaluation of the patient’s clinical framework and follows an instrumental procedure, depending on the clinical severity of the patient. Dental practitioners have the ability to intercept early on the signs and symptoms of OSAS. At the same time, they can assess whether the patient has the indications for treatment with specific oral devices (Oral Appliances, OA). The purpose of this paper is to provide guidance for dental management of obstructive sleep apnea syndrome in adult individuals.展开更多
People with visual impairments(PwVI)represent a heterogeneous social group who often experience significant disabling barriers in exercising their rights throughout their life course.Understanding dimensions of vulner...People with visual impairments(PwVI)represent a heterogeneous social group who often experience significant disabling barriers in exercising their rights throughout their life course.Understanding dimensions of vulnerability of PwVI to disasters and climate change is an important issue to reduce the culture of neglected disasters.To date,few studies have analyzed visual impairment and disaster risk reduction(DRR)in the countries of Latin America and the Caribbean.This exploratory qualitative research project analyzed how to include PwVI in the DRR policies of Brazil.The research question is:how can we include PwVI in the discussion of DRR and climate change?The response to this question is part of a joint effort that involved a university,a hazard monitoring agency,and three institutions that work with PwVI.The three main results of the project are:(1)a mapping method to identify the exposure of PwVI to landslides and floods,and to create tactile risk maps tailored to them;(2)incorporating the voices of PwVI regarding their vulnerabilities and capacities with respect to disasters and climate change,achieved through shared interaction during 15 face to face interviews and one workshop attended by 100 people;and(3)an initiative of inclusive education to reduce some of the disabling barriers that intensify vulnerability.展开更多
Background:Cyperi Rhizoma,derived from Cyperus rotundus L.,is a widely used medicinal herb in traditional Chinese medicine(TCM),with Shandong Province recognized as its geo-authentic habitat.However,the quality of Cyp...Background:Cyperi Rhizoma,derived from Cyperus rotundus L.,is a widely used medicinal herb in traditional Chinese medicine(TCM),with Shandong Province recognized as its geo-authentic habitat.However,the quality of Cyperi Rhizoma varies significantly across different regions,potentially influencing its therapeutic efficacy.This study investigates the influence of geographic origin on the chemical composition and overall quality of Cyperi Rhizoma.Methods:A comprehensive approach,including traditional quality assessment,GC-MS(g as c hromatography-m ass s pectrometry),RP-HPLC(r everse p hase h igh-p erformance l iquid c hromatography),and FT-IR(f ourier t ransform i nfrared s pectroscopy)techniques,was employed to analyze Cyperi Rhizoma samples from Shandong Province.These methods examined the physical appearance,chemical profile,and content variations,particularly focusing onα-cyperone.Results:Traditional quality assessments revealed noticeable differences in the external characteristics of the samples.GC-MS analysis identified a variety of unique chemical constituents,while RP-HPLC and FT-IR showed significant variations inα-cyperone content,with higher levels found in Shandong samples.Conclusion:These results demonstrate that geographic origin is a critical determinant of Cyperi Rhizoma quality,with Shandong specimens exhibiting superiorα-cyperone levels and characteristic phytochemical profiles.This validates the geo-authenticity concept in TCM and provides actionable data for developing evidence-based quality standards,suggesting that provenance should be prioritized in medicinal material selection and pharmacopeial specifications.展开更多
文摘Obstructive Sleep Apnea Syndrome (OSAS) is a respiratory sleep disorder characterized by repeated episodes of complete or partial obstruction of the upper airway. OSAS has a frequency of 4 percent and is classified according to the number of obstructive sleep apnea-hypopnea episodes. The OSAS diagnostic path starts with the evaluation of the patient’s clinical framework and follows an instrumental procedure, depending on the clinical severity of the patient. Dental practitioners have the ability to intercept early on the signs and symptoms of OSAS. At the same time, they can assess whether the patient has the indications for treatment with specific oral devices (Oral Appliances, OA). The purpose of this paper is to provide guidance for dental management of obstructive sleep apnea syndrome in adult individuals.
基金the Sao Paulo Research Foundation–Fapesp (Grant Number 2018/06093-4).
文摘People with visual impairments(PwVI)represent a heterogeneous social group who often experience significant disabling barriers in exercising their rights throughout their life course.Understanding dimensions of vulnerability of PwVI to disasters and climate change is an important issue to reduce the culture of neglected disasters.To date,few studies have analyzed visual impairment and disaster risk reduction(DRR)in the countries of Latin America and the Caribbean.This exploratory qualitative research project analyzed how to include PwVI in the DRR policies of Brazil.The research question is:how can we include PwVI in the discussion of DRR and climate change?The response to this question is part of a joint effort that involved a university,a hazard monitoring agency,and three institutions that work with PwVI.The three main results of the project are:(1)a mapping method to identify the exposure of PwVI to landslides and floods,and to create tactile risk maps tailored to them;(2)incorporating the voices of PwVI regarding their vulnerabilities and capacities with respect to disasters and climate change,achieved through shared interaction during 15 face to face interviews and one workshop attended by 100 people;and(3)an initiative of inclusive education to reduce some of the disabling barriers that intensify vulnerability.
基金supported by the National Natural Science Foundation of China(No.82204610)Qihang Talent Program(L2022046)+1 种基金the Scientific and Technological Innovation Project of China Academy of Chinese Medical Sciences(CI2021A04013)Fundamental Research Funds for the Central Public Welfare Research Institutes(ZZ15-YQ-041 and L2021029).
文摘Background:Cyperi Rhizoma,derived from Cyperus rotundus L.,is a widely used medicinal herb in traditional Chinese medicine(TCM),with Shandong Province recognized as its geo-authentic habitat.However,the quality of Cyperi Rhizoma varies significantly across different regions,potentially influencing its therapeutic efficacy.This study investigates the influence of geographic origin on the chemical composition and overall quality of Cyperi Rhizoma.Methods:A comprehensive approach,including traditional quality assessment,GC-MS(g as c hromatography-m ass s pectrometry),RP-HPLC(r everse p hase h igh-p erformance l iquid c hromatography),and FT-IR(f ourier t ransform i nfrared s pectroscopy)techniques,was employed to analyze Cyperi Rhizoma samples from Shandong Province.These methods examined the physical appearance,chemical profile,and content variations,particularly focusing onα-cyperone.Results:Traditional quality assessments revealed noticeable differences in the external characteristics of the samples.GC-MS analysis identified a variety of unique chemical constituents,while RP-HPLC and FT-IR showed significant variations inα-cyperone content,with higher levels found in Shandong samples.Conclusion:These results demonstrate that geographic origin is a critical determinant of Cyperi Rhizoma quality,with Shandong specimens exhibiting superiorα-cyperone levels and characteristic phytochemical profiles.This validates the geo-authenticity concept in TCM and provides actionable data for developing evidence-based quality standards,suggesting that provenance should be prioritized in medicinal material selection and pharmacopeial specifications.
