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香港结核病与吸烟调查 被引量:5
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作者 C.C.Leung C.K.Chan +8 位作者 C.M.Tam K.C.Chang C.H.Chau W.S.Law W.W.Yew C.H.Chau C.W.Lam K.S.Lau 贺晓新 《国际结核病与肺部疾病杂志》 2003年第4期133-138,共6页
目的:了解在香港人群中吸烟与结核病的联系。方法:利用间接调整法比较1996年报告登记的851例结核病人样本与一般人群的吸烟率。并利用分层单因素分析和多元logisitc回归分析方法比较了曾吸烟者与不吸烟者的临床特征。结果:与人群对照相... 目的:了解在香港人群中吸烟与结核病的联系。方法:利用间接调整法比较1996年报告登记的851例结核病人样本与一般人群的吸烟率。并利用分层单因素分析和多元logisitc回归分析方法比较了曾吸烟者与不吸烟者的临床特征。结果:与人群对照相比,结核病人的吸烟率较高。在16-64岁组,吸烟与结核病之间的比值比(OR)在男性和女性分别为2.44和2.08(Mantel-Haenszel加权OR=2.40,P<0.001);在65岁以上组,则分别为 2.09和2.83(Mantel-Haenszel加权 OR=2.19,P<0.001)。男性、65岁以上、发病时仍在工作、经 常饮酒、吸毒以及无结核病接触史等与吸烟有关(P<0.05)。曾吸烟者的咳嗽比例高(OR=1.69)、容易憋气(OR=1.84)、上肺区受累多(OR=1.67)、易发空洞(OR=1.76)和粟粒性肺结核(OR=2.77)以及痰菌培养阳性的概率较大(OR=1.43),但发生孤立肺外结核病的机会要小(OR=0.31),即使控制了背景因素的混杂作用后也如此(P<0.05)。结论:吸烟与结核病有关。严重类型的肺结核多见于曾吸烟者。 展开更多
关键词 吸烟 结核病 男性 年长者
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中国利福喷丁在香港临床研究期间的生物利用度 被引量:1
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作者 C.M.Tam S.L.Chan +3 位作者 C.W.Lam J.M.Dickinson D.A.Mitchison 屠德华 《国际结核病与肺部疾病杂志》 1998年第1期28-33,共6页
背景:利福喷丁在香港的临床研究。目的:评价研究中所使用的中国利福喷丁的生物利用度。设计:通过微生物学试验测定给予四批药物的287名病人血清标本中利福喷丁的含量结果:从40名病人中随机分配给西方或中国的利福喷丁所获得的首批曲线... 背景:利福喷丁在香港的临床研究。目的:评价研究中所使用的中国利福喷丁的生物利用度。设计:通过微生物学试验测定给予四批药物的287名病人血清标本中利福喷丁的含量结果:从40名病人中随机分配给西方或中国的利福喷丁所获得的首批曲线区域图对比显示:中国利福喷丁生物利用度是西方药物的74%。第二批药的生物利用度发现是西方的66%,最后二批利福喷丁的剂量由计划的600mg增至750mg或短时增至900mg,则血清中浓度同西方药获得的相类似,在每批药使用期间生物利用度没有变化。结论:通过比较开始二批和最后二批试验的结果将估价利福喷丁剂量对疗效和毒性的作用。 展开更多
关键词 利福喷丁 生物利用度 香港 剂量
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Colon cancer in a patient with underlying aplastic anemia: A clinical challenge
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作者 Hilda Wong Pierre Chan Thomas Yau 《World Journal of Clinical Oncology》 CAS 2012年第2期29-31,共3页
The association of gastrointestinal malignancy with aplastic anemia has rarely been reported in the literature. Although it is not clear whether there is any direct relationship between aplastic anemia and gastrointes... The association of gastrointestinal malignancy with aplastic anemia has rarely been reported in the literature. Although it is not clear whether there is any direct relationship between aplastic anemia and gastrointestinal cancers, a retrospective analysis did suggest the notion that patients with aplastic anemia might have a higher incidence of colorectal cancer. Here, we report the diagnostic and therapeutic challenges in managing a patient with aplastic anemia and advanced colorectal cancer. Early diagnosis is challenging due to overlapping symptomatology and clinical features, increased risk of diagnostic procedures, and confounding complications arising from aplastic anemia and its treatment. A high index of suspicion and multidisciplinary input are essential. 展开更多
关键词 APLASTIC ANEMIA COLON cancer GASTROINTESTINAL MALIGNANCY
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Three Courses of Tianjiu Therapy in Sanfu Days for Chronic Asthma: A Clinic Efficacy Observation Trail
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作者 Yangyang Tan Kwaiching Lo +5 位作者 Waiho Tse Clara Waichung Chan Kimshing Lau Stacey S. Cherny Lixing Lao Lei Li 《Chinese Medicine》 2017年第2期43-71,共29页
Objective: This study was aimed to compare the efficacy among chronic asthma patients who received 1 course treatment, 2 courses treatment and 3 courses treatment of Tianjiu Therapy in Sanfu Days. Methods: This study ... Objective: This study was aimed to compare the efficacy among chronic asthma patients who received 1 course treatment, 2 courses treatment and 3 courses treatment of Tianjiu Therapy in Sanfu Days. Methods: This study was comparing efficiency with 3 courses (baseline, the 1st course, the 2nd course, the 3rd course) of Tianjiu Therapy for asthma in 91 chronic asthma patients. For each course, patients received 3 times Tianjiu Therapy treatments, pretreatment assessment and posttrestment assessment. Results: 91 asthma participants completed at least 3 courses of Tianjiu Therapy in Sanfu Days. 1) Days for asthma attacked during the last 12 months;the frequency for asthma attacked during the last 12 months;incidence of admitting to clinic (Integrated Chinese Medicine & Western Medicine Clinic) when asthma attack during the last 12 months;times of admitting to clinic;times of solving by persistent medicine;times of solving by own medicine when asthma attack during the last 12 months;and symptoms associated with Chinese medicine of waking by asthma symptoms, lack of strength, lassitude, rapid or difficult breathing were improved at the 1st course, the 2nd course and the 3rd course compared with baseline (All P < 0.05);2) The incidence of admitting to In-patient Hospital and solving by persistent prescription when asthma attacked;the frequency of Chinese Herbal Medicine used during Tianjiu Therapy;the status of asthma under controlled and no improved by self-evaluation were similarly improved at the 2nd course and the 3rd course (All P 3) Incidence of admitting to A & E for asthma attacked during the last 12 months, and other treatments except Western Medicine, Chinese Herbal Medicine, and Acupuncture & Moxibution during the last 12 months were improvement at the 3rd course (All P 4) Symptoms associated with Chinese medicine of spontaneous sweating and reduction of exercise were improved at the 1st course (P < 0.05);5) Symptom of diarrhea after intake of oil food was became a little bad at the 2nd course and the 3rd course (P < 0.05);6) The frequency of bronchodilator used when asthma attack was reduced in the 1st course and the 2nd course (All P < 0.05);7) Lung function of FEV1 and FEV1/FVC(×100) were a little improvement, but have no significant statistical difference (P > 0.05);8) The total score of ACT at the 1st course, the 2nd course, and the 3rd course did not improved significantly (All P > 0.05). Conclusion: After Tianjiu Therapy in Sanfu Days participants have achieved good efficiency, and as the course get longer, the efficiency of more symptoms associated with chronic asthma were improved. Suggest patients with chronic asthma continuous receive Tianjiu Therapy in Sanfu Days which will be a feasible treatment. 展开更多
关键词 Tianjiu THERAPY Sanfu DAYS ASTHMA
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