Associating Liver Partition and Portal vein ligation for Staged hepatectomy(ALPPS),an innovative procedure in liver surgery,capacitated resection of previously unresectable liver tumors.Originally ALPPS was predominan...Associating Liver Partition and Portal vein ligation for Staged hepatectomy(ALPPS),an innovative procedure in liver surgery,capacitated resection of previously unresectable liver tumors.Originally ALPPS was predominantly applied in patients suffering from extensive colorectal liver metastases(CRLM)with good results(1).ALPPS is thought to exploit liver’s ability to regenerate upon mechanical injury,while safeguarding against liver failure by temporarily leaving a deportalized and detached portion of the liver afflicted with disease.The non-tumorous tissue of the diseased portion is entrusted to support liver function during the regeneration process,thus preventing overexertion of the hepatocytes in the remnant that would otherwise cause their demise.展开更多
文摘Associating Liver Partition and Portal vein ligation for Staged hepatectomy(ALPPS),an innovative procedure in liver surgery,capacitated resection of previously unresectable liver tumors.Originally ALPPS was predominantly applied in patients suffering from extensive colorectal liver metastases(CRLM)with good results(1).ALPPS is thought to exploit liver’s ability to regenerate upon mechanical injury,while safeguarding against liver failure by temporarily leaving a deportalized and detached portion of the liver afflicted with disease.The non-tumorous tissue of the diseased portion is entrusted to support liver function during the regeneration process,thus preventing overexertion of the hepatocytes in the remnant that would otherwise cause their demise.
