Organic electrochemical transistors(OECTs)have emerged as essential components in various applications,including bioelectronics,neuromorphics,sensing,and flexible electronics.Recently,efforts have been directed toward...Organic electrochemical transistors(OECTs)have emerged as essential components in various applications,including bioelectronics,neuromorphics,sensing,and flexible electronics.Recently,efforts have been directed toward developing flexible and sustainable OECTs to enhance their integration into wearable and implantable biomedical devices.In this work,we introduce a novel PEDOT:Sacran bio-nanocomposite as a channel material for flexible and biodegradable OECTs.Sacran,a high-molecular-weight polysaccharide derived from blue-green algae,possesses exceptional ionic conductivity,water retention,and biocompatibility,making it a promising candidate for bioelectronic applications.We successfully fabricated ultrathin and flexible OECTs on poly(ethylene terephthalate)(PET)foils,achieving transconductance values up to 7.4 mS.The devices exhibited stable ion-to-electron transduction after mechanical deformation.The OECTs were further demonstrated on eco-friendly and biodegradable poly(lactic acid)(PLA)substrates,achieving a transconductance of 1.6 mS and undergoing enzymatic hydrolysis under controlled conditions.This study highlights the potential of Sacran-based conductive bio-nanocomposites in advancing sustainable bioelectronic devices.展开更多
Quantum calculations(mainly DFT)and molecular dynamics are increasingly effective tools to evaluate the physical chemical properties of natural and bio-inspired compounds.Free Radical Scavenging Capacity.Thermodynamic...Quantum calculations(mainly DFT)and molecular dynamics are increasingly effective tools to evaluate the physical chemical properties of natural and bio-inspired compounds.Free Radical Scavenging Capacity.Thermodynamic parameters(mainly bond dissociation enthalpies(BDE)of the O-H phenolic bond)allowed an accurate prediction of the antioxidant capacities of展开更多
基金funded by the State of Upper Austria and the Federal Ministry of Education,Science and Research for the Young Researcher Project“BIOCOM”grant(LIT-2022-11-YOU-221)support of the Austrian Science Foundation(FWF)with the Wittgenstein Prize(Z222 N19)+3 种基金support by the European Union’s Horizon 2020 research and innovation programme under grant agreement number 101016411“Soft Milli-robotsSOMIRO”and European Research Council(ERC)Starting Grant“GEL-SYS”under grant agreement number 757931the Research Infrastructure Nano EnviCz,supported by the Ministry of Education,Youth and Sports of the Czech Republic under project no.LM2023066the European Regional Development Fund—Project Excellence in Regenerative Medicine(No.CZ.02.01.01/00/22_008/0004562)support from the project‘EINSTEIN’’,project no.101136377(HORIZON-WIDERA-2023-ACCESS-03)。
文摘Organic electrochemical transistors(OECTs)have emerged as essential components in various applications,including bioelectronics,neuromorphics,sensing,and flexible electronics.Recently,efforts have been directed toward developing flexible and sustainable OECTs to enhance their integration into wearable and implantable biomedical devices.In this work,we introduce a novel PEDOT:Sacran bio-nanocomposite as a channel material for flexible and biodegradable OECTs.Sacran,a high-molecular-weight polysaccharide derived from blue-green algae,possesses exceptional ionic conductivity,water retention,and biocompatibility,making it a promising candidate for bioelectronic applications.We successfully fabricated ultrathin and flexible OECTs on poly(ethylene terephthalate)(PET)foils,achieving transconductance values up to 7.4 mS.The devices exhibited stable ion-to-electron transduction after mechanical deformation.The OECTs were further demonstrated on eco-friendly and biodegradable poly(lactic acid)(PLA)substrates,achieving a transconductance of 1.6 mS and undergoing enzymatic hydrolysis under controlled conditions.This study highlights the potential of Sacran-based conductive bio-nanocomposites in advancing sustainable bioelectronic devices.
文摘Quantum calculations(mainly DFT)and molecular dynamics are increasingly effective tools to evaluate the physical chemical properties of natural and bio-inspired compounds.Free Radical Scavenging Capacity.Thermodynamic parameters(mainly bond dissociation enthalpies(BDE)of the O-H phenolic bond)allowed an accurate prediction of the antioxidant capacities of
