There is growing concern that increasing concentrations of greenhouse gases in the atmosphere have been responsible for global warming through their effect on radiation balance and temperature. The magnitude of emissi...There is growing concern that increasing concentrations of greenhouse gases in the atmosphere have been responsible for global warming through their effect on radiation balance and temperature. The magnitude of emissions and the relative importance of different sources vary widely, regionally and locally. The Indus Basin of Pakistan is the food basket of the country and agricultural activities are vulnerable to the effects of global warming due to accelerated emissions of GHGs. Many developments have taken place in the agricultural sector of Pakistan in recent decades in the background of the changing role of the government and the encouragement of the private sector for investment in new ventures. These interventions have considerable GHG emission potential. Unfortunately, no published information is currently available on GHG concentrations in the Indus Basin to assess their magnitude and emission trends. The present study is an attempt to estimate GHG （CO2, CH4 and N2O） emissions arising from different agro-ecosystems of Indus Basin. The GHGs were estimated mostly using the IPCC Guidelines and data from the published literature. The results showed that CH4 emissions were the highest （4.126 Tg yr^-1） followed by N20 （0.265 Tg yr^-1） and CO2 （52.6 Tg yr^-1）. The sources of CH4 are enteric fermentation, rice cultivation and cultivation of other crops. N2O is formed by microbial denitrification of NO3 produced from applied fertilizer-N on cropped soils or by mineralization of native organic matter on fallow soils. CO2 is formed by the burning of plant residue and by soil respiration due to the decomposition of soil organic matter.展开更多
Laser Induced Breakdown Spectroscopic(LIBS)technique was used to detect calcium and silicon in an unknown sample.In this method plasma was generated by Nd∶YAG laser of wavelength 1 064 nm with energy 400 mJ and pulse...Laser Induced Breakdown Spectroscopic(LIBS)technique was used to detect calcium and silicon in an unknown sample.In this method plasma was generated by Nd∶YAG laser of wavelength 1 064 nm with energy 400 mJ and pulse duration between 5~10ns.The method was applied for the qualitative as well as quantitative analysis.In the qualitative analysis,the electron number density(Ne)of plasma containing calcium and silicon is determined showing that Neof neutral particles is equivalent to 1016(cm-3)whereas for ionized particles it is 1017(cm-3).Plasma temperature is measured using Boltzmann plot method which must be greater than 10 000 k.Intensity ratio method is used for the quantitative analysis shows various elements in abundance with calcium and silicon in majority.展开更多
The oxidation resistance behavior of SmCo(2:17)-type high-temperature magnets modified with Ni-Cr two-layer coating was studied. The study depicts the mass gain kinetics and magnetic properties of uncoated and NiCr-mo...The oxidation resistance behavior of SmCo(2:17)-type high-temperature magnets modified with Ni-Cr two-layer coating was studied. The study depicts the mass gain kinetics and magnetic properties of uncoated and NiCr-modified magnets oxidized at high temperature(500 ℃) in air for 200 h. The oxidation test results illustrate that the mass gain of uncoated magnet is6.95 mg·cm^(-2) which is more than that(0.08 mg·cm^(-2)) of coated magnet after 200 h. For the magnetic properties concerned, there is a great loss for uncoated magnet, while for coated magnet, magnetic properties do not change much. The study of uncoated magnet through X-ray diffraction(XRD) and electron probe microanalysis(EPMA) shows that the invasion of oxygen at high temperature leads to the loss of magnetic properties by changing the microstructure of magnet.展开更多
A comparative study on the prevalence of Anaplasma parasite was conducted on ticks carrying buffaloes and cattle. Five hundred blood samples of both animals (250 of each) were collected during February, March and Apri...A comparative study on the prevalence of Anaplasma parasite was conducted on ticks carrying buffaloes and cattle. Five hundred blood samples of both animals (250 of each) were collected during February, March and April. Thin blood smears on glass slides were made, fixed in 100% methyl alcohol and examined. Microscopic examination revealed that 205 (41%) animals had Anaplasma parasites, out of which 89, 44 and 72 animals had Anaplasma marginale, Anaplasma centrale and mixed infection respectively. Infected buffaloes and cattle were 75 and 130 respectively. The infection in female was 53 and 92 in buffaloes and cattle respectively. Twenty-two and 92 blood samples of male were found positive in buffaloes and cattle respectively. Com- parative study revealed that the cattle were 26.82% more susceptible than buffaloes. The parasite prevailing percentage in female of both animals was slightly higher than that of the male. This investigation was aimed at studying the comparative prevalence of Anaplasma parasite in tick carrying buffaloes and cattle.展开更多
The present study focuses on building a workflow for structural interpretation and velocity modeling and implementing to Jurassic-Cretaceous succession （Chiltan Limestone and Massive sand of the Lower Goru Formation...The present study focuses on building a workflow for structural interpretation and velocity modeling and implementing to Jurassic-Cretaceous succession （Chiltan Limestone and Massive sand of the Lower Goru Formation）. 2D-Migrated seismic sections of the area are used as data set and in order to confirm the presence of hydrocarbons in the study area, P and S-wave seismic velocities are estimated from single-component seismic data. Some specific issues in the use of seismic data for modeling and hydrocarbon evaluation need to deal with including distinguishing the reservoir and cap rocks, and the effects of faults, folds and presence of hydrocarbons on these rocks. This study has carried out the structural interpretation and modeling of the seismic data for the identification of traps. The results demonstrate existence of appropriate structural traps in the form of horst and grabens in the area. 2D and 3D velocity modeling of the horizons indicates the presence of high velocity zones in the eastern half of the study while relatively low velocity zones are encountered in the western half of the area. Two wells were drilled in the study area （i.e. Fateh-01 and Ichhri-01） and both are dry. Immature hydrocarbons migration is considered as a failure reason for Fateh-01 and Ichhri-01 well.展开更多
Some biologically important tin（Ⅳ） complexes derived from 5,5-diethyl sodium barbital have been synthesized and characterized through various analytical and spectroscopic techniques such as IR, ^1H-, ^13C-NMR and ^...Some biologically important tin（Ⅳ） complexes derived from 5,5-diethyl sodium barbital have been synthesized and characterized through various analytical and spectroscopic techniques such as IR, ^1H-, ^13C-NMR and ^119mSn mossbauer. On the basis of these spectroscopic techniques, octahedral geometry has been assigned to all the novel compounds. These complexes, soluble in DMSO and DMF, were screened against a wide range of microorganisms. The results proved that the diphenyltin（Ⅳ） and dibutyltin（Ⅳ） complexes exhibit excellent activity against all types of microorganisms, while the rest of the compounds show significant activity that can be used during the biological study.展开更多
The present paper represents the ethnopharmacological survey of Sudhan Gali,Kashmir,Pakistan.The study revealed that 12 plant species belonging to 11 families were used for the treatment of stomach,diabetes and ophtha...The present paper represents the ethnopharmacological survey of Sudhan Gali,Kashmir,Pakistan.The study revealed that 12 plant species belonging to 11 families were used for the treatment of stomach,diabetes and ophthalmic diseases by the local people in Sudhan Gali.Achillea millefolium,Aconitum heterophyllum,Berberis lycium,Polygonum amplexicaule,Mentha longifolia,Paeonia emodi,Plantago lanceolata were locally used for stomach related problems treatment;Berberis lycium,Skimmia lareola,Solanum dulcamara for diabetes and Geranium wallichianum,Artemisia vulgaris,Solanum dulcamara,and Corydalis crassifolia used for the treatment of ophthalmic diseases.Two species Berberis lycium and Solanum dulcamara have multipurpose value.Former is used to treat stomach as well as diabetes while latter is used to treat not only to diabetes but also ophthalmic diseases.According to IUCN categories,out of these 12 plant species collected and marketed,Polygonum amplexicaule and Paeonia emodi are endangered,Aconitum heterophyllum;Berberis lycium species are vulnerable while Plantago lanceolata and Skimmia lareola species are rare.The availability of these medicinal plants has decreased during the past 20 years and these are facing a drastic biotic pressure due to their extensive usage and non-scientific methods of collection.It is quite evident that these valuable native medicinal plants species are going to decline in number and ultimately will become extinct if no timely proper conservation strategies are adopted.展开更多
Five triorganotin（IV） （1-5） complexes of cinnamic acid, （Z）-2-acetamido-3-phenylacrylic acid, 3-methylbut-2-enoic acid, and 2,2-diphenylacetic acid have been synthesized and characterized by IH-13C-119Sn NMR, UV...Five triorganotin（IV） （1-5） complexes of cinnamic acid, （Z）-2-acetamido-3-phenylacrylic acid, 3-methylbut-2-enoic acid, and 2,2-diphenylacetic acid have been synthesized and characterized by IH-13C-119Sn NMR, UV, and IR. The spectroscopic investigation demonstrated that the carboxylate group acts as a monodentate ligand in triorganotin（IV） compounds. Five triorganotin（IV） complexes were screened against the log phase culture of Mycobacterium tuberculosis H37Rv by colorimetric method using XTT dye as growth indicator. The MICs were found to he 0.08 and 1.25μg/mL.展开更多
The present study deals with the depositional facies, diagenetic processes and sequence stratigraphy of the shallow marine carbonates of the Samana Suk Formation, Kohat Basin, in order to elucidate its reservoir quali...The present study deals with the depositional facies, diagenetic processes and sequence stratigraphy of the shallow marine carbonates of the Samana Suk Formation, Kohat Basin, in order to elucidate its reservoir quality. The Samana Suk Formation consists of thin to thick-bedded, oolitic, bioclastic, dolomitic and fractured limestone. Based on the integration of outcrop, petrographic and biofacies analyses, the unit is thought to have been deposited on a gentle homoclinal ramp in peritidal, lagoonal and carbonate shoal settings. Frequent variations in microfacies based sea-level curve have revealed seven Transgressive Systems Tracts(TSTs) and six Regressive Systems Tracts(RSTs). The unit has undergone various stages of diagenetic processes, including mechanical and chemical compaction, cementation,micritization, dissolution and dolomitization. The petrographic analyses show the evolution of porosity in various depositional and diagenetic phases. The fenestral porosity was mainly developed in peritidal carbonates during deposition,while the burial dissolution and diagenetic dolomitization have greatly enhanced the reservoir potential of the rock unit, as is further confirmed by the plug porosity and permeability analyses. The porosities and permeabilities were higher in shoal facies deposited in TSTs, as compared to lagoonal and peritidal facies, except for the dolomite in mudstone, deposited during RSTs. Hence good, moderate and poor reservoir potential is suggested for shoal, lagoonal and peritidal facies,respectively.展开更多
In the present study, a co-culture technique was adopted with an aim to investigate a hyper production of exoglucanase, and β-glucosidase using cheap and easily available agro-industrial residue corn stover as growth...In the present study, a co-culture technique was adopted with an aim to investigate a hyper production of exoglucanase, and β-glucosidase using cheap and easily available agro-industrial residue corn stover as growth supporting substrate. Various physio-chemical and nutritional variables were optimized using classical and completely randomized designs for induced production of exoglucanase, and β-glucosidase from the co-culture of Trichoderma viride and Ganoderma lucidum in solid state fermentation (SSF). Analysis profile showed that when the conditions of the SSF medium containing 15 g corn stover substrate (50% w/w moisture) inoculated with 6 mL of inoculum were optimal, the maximum productions of exoglucanase (485 ± 6.5 U/mL) and β-glucosidase (255 ± 3.3 U/mL) were recorded after 5 days of incubation at pH 6 and 35°C.展开更多
The present paper addresses the megnetohydrodynamic Jeffrey fluid flow with heat and mass transfer on an infinitely rotating upright cone. Inquiry is carried out with heat source/sink and chemical reaction effects.Fur...The present paper addresses the megnetohydrodynamic Jeffrey fluid flow with heat and mass transfer on an infinitely rotating upright cone. Inquiry is carried out with heat source/sink and chemical reaction effects.Further, constant thermal and concentration flux situations are imposed. Optimal homotopy analysis method (OHAM) is employed to achieve series solutions of the concerned differential equations. Important results of the flow phenomena are explored and deliberated by means of graphs and numerical tables. It is perceived that thermal boundary layer thickness possess contrast variations for the heat source and heat sink, respectively. The chemical reaction enhances the heat transfer rate but decline the mass transfer rate. Moreover, the precision of the existing findings is verified by associating them with the previously available work.展开更多
The differential cross section data for high energy K-p elastic scattering showing a break near-t=4(Gev/c)^(2) have been fitted for pL=20,100 and 200GeV/c with-t extended up to 14(Gev/c)^(2) by using a dipole pomeron ...The differential cross section data for high energy K-p elastic scattering showing a break near-t=4(Gev/c)^(2) have been fitted for pL=20,100 and 200GeV/c with-t extended up to 14(Gev/c)^(2) by using a dipole pomeron mode.展开更多
The inability of traditional privacy-preserving models to protect multiple datasets based on sensitive attributes has prompted researchers to propose models such as SLOMS,SLAMSA,(p,k)-Angelization,and(p,l)-Angelizatio...The inability of traditional privacy-preserving models to protect multiple datasets based on sensitive attributes has prompted researchers to propose models such as SLOMS,SLAMSA,(p,k)-Angelization,and(p,l)-Angelization,but these were found to be insufficient in terms of robust privacy and performance.(p,l)-Angelization was successful against different privacy disclosures,but it was not efficient.To the best of our knowledge,no robust privacy model based on fuzzy logic has been proposed to protect the privacy of sensitive attributes with multiple records.In this paper,we suggest an improved version of(p,l)-Angelization based on a hybrid AI approach and privacy-preserving approach like Generalization.Fuzz-classification(p,l)-Angel uses artificial intelligence based fuzzy logic for classification,a high-dimensional segmentation technique for segmenting quasi-identifiers and multiple sensitive attributes.We demonstrate the feasibility of the proposed solution by modelling and analyzing privacy violations using High-Level Petri Nets.The results of the experiment demonstrate that the proposed approach produces better results in terms of efficiency and utility.展开更多
By performing one-dimensional particle-in-cell simulations, the nonlinear effects of electronacoustic(EA) waves are investigated in a multispecies plasma, whose constituents are hot electrons, cold electrons, and beam...By performing one-dimensional particle-in-cell simulations, the nonlinear effects of electronacoustic(EA) waves are investigated in a multispecies plasma, whose constituents are hot electrons, cold electrons, and beam electrons with immobile neutralized positive ions. Numerical analyses have identified that EA waves with a sufficiently large amplitude tend to trap cold electrons. Because EA waves are dispersive, where the wave modes with different wavenumbers have different phase velocities, the trapping may lead to the mixing of cold electrons. The cold electrons finally get thermalized or heated. The investigation also shows that the excited EA waves give rise to a broad range of wave frequencies, which may be helpful for understanding the broadband-electrostatic-noise spectrum in the Earth’s auroral region.展开更多
Gestational diabetes mellitus(GDM)is defined as any degree of glucose or carbohydrate intolerance mainly during pregnancy.About 10%to 15%of pregnancies are affected and complicated by gestational diabetes.Due to hormo...Gestational diabetes mellitus(GDM)is defined as any degree of glucose or carbohydrate intolerance mainly during pregnancy.About 10%to 15%of pregnancies are affected and complicated by gestational diabetes.Due to hormonal changes during pregnancy,the requirement for insulin increases,and thus the usual concentration of insulin previously catered for glycemic control is ineffective.In order to meet the body’s demand,the islet cells secrete a higher amount of insulin.GDM occurs when this higher concentration is also unable to control blood glucose.This increased resistance toward insulin is most noticeable during the third trimester of pregnancy,which gradually normalizes after the termination of pregnancy.Various complications do arise,which affect both the mother and her developing fetus.In the mother,miscarriages,delivery of baby via caesarian section,and other complications may result,whereas the fetus may be affected with congenital abnormalities,neonatal hypoglycemia,and even death.Treatment of GDM includes both non-pharmacological and pharmacological interventions.Pharmacological agents are employed when non-pharmacological interventions fail to achieve the desired target.Glyburide,insulin,and metformin are the commonly used pharmacological agents.展开更多
This paper is about short review of earthquake statistics and efforts for earthquake mitigation, hazard and risk assessment studies in Pakistan. Pakistan and adjoining region lying between longitude 60°E to 78...This paper is about short review of earthquake statistics and efforts for earthquake mitigation, hazard and risk assessment studies in Pakistan. Pakistan and adjoining region lying between longitude 60°E to 78°E and latitude 20°N to 45°N are selected for the study as this region has a history of many large earthquakes because of its location in the region of intersection of three plates namely Indian, Eurasian and Arabian Sea plate. This paper is based on the study of both seismological history of the region which includes recent and historical seismicity based on earthquake catalogue as well as geological knowledge supplemented with available fault system information. In this study, Pakistan and adjoining regions are divided into 14 seismogenic zones. Seismicity of each zone is studied considering also the major cities in the respective zone and type of infrastructure which is mainly responsible for earthquake disaster rather than earthquake itself.展开更多
The application of artificial intelligence(AI)in medicine,particularly through machine learning(ML),marked a significant progression in drug discovery.AI acts as a powerful catalyst in narrowing the gap between diseas...The application of artificial intelligence(AI)in medicine,particularly through machine learning(ML),marked a significant progression in drug discovery.AI acts as a powerful catalyst in narrowing the gap between disease understanding and the identification of potential therapeutic agents.This review provides an inclusive summary of the latest advancements in AI and its application in drug discovery.We examine the various stages of the drug discovery process,starting from disease identification and encompassing diagnosis,target identification,screening,and lead discovery.AI's capability to analyze extensive datasets and discern patterns is essential in these stages,enhancing predictions and efficiencies in disease identification,drug discovery,and clinical trial management.The role of AI in expediting drug development is emphasized,highlighting its potential to analyze vast data volumes,thus reducing the time and costs associated with new drug market introduction.The importance of data quality,algorithm training,and ethical considerations,especially in patient data handling during clinical trials,is addressed.By considering these factors,AI promises to transform drug development,offering significant benefits to patients and society.展开更多
The widespread presence of per-and polyfluoroalkyl substances(PFAS)in the environment poses a serious threat due to their persistent nature and harmful effects on human health and ecosystems.In this context,there is a...The widespread presence of per-and polyfluoroalkyl substances(PFAS)in the environment poses a serious threat due to their persistent nature and harmful effects on human health and ecosystems.In this context,there is an imperative need for developing and improving methods to identify and eliminate these contaminants.Different detection techniques that are being used for PFAS detection are discussed.The details of detection mechanism of these techniques,their limitations and future areas of research for their optimization and improvement in detection efficiencies are also discussed in this review.Besides,this article provides a baseline for anticipating the advanced treatment technologies for PFAS in drinking water.We focus on the effectiveness of different removal techniques(physical,biological and chemical advancements)for eliminating various types of short and long chain PFAS.More so,the methods for the removal of PFAS are also explained with their limitations and future outlooks.Their pros and cons and limitations that need to be overcome and could be the potential future research.We included the recent literature and encompassed the information of PFAS related to guidelines,analytical techniques to determine PFAS and treatment or removal technologies.Conclusively,this study suggests that a combination of treatment methods will likely be necessary for effective PFAS remediation in water.展开更多
The synthesis and in vitro antifungal activity of some Schiff bases and their Sn (Ⅳ) complexes has been tested against plant pathogenic fungi and it is found that they possess excellent fungicidal activity. On the ba...The synthesis and in vitro antifungal activity of some Schiff bases and their Sn (Ⅳ) complexes has been tested against plant pathogenic fungi and it is found that they possess excellent fungicidal activity. On the basis of ^1H-, ^13C-,^119Sn NMR-, ^119Sn Mǒssbauer, IR and Elemental analysis the tetrahedral geometry is proposed for the synthesized compounds.展开更多
文摘There is growing concern that increasing concentrations of greenhouse gases in the atmosphere have been responsible for global warming through their effect on radiation balance and temperature. The magnitude of emissions and the relative importance of different sources vary widely, regionally and locally. The Indus Basin of Pakistan is the food basket of the country and agricultural activities are vulnerable to the effects of global warming due to accelerated emissions of GHGs. Many developments have taken place in the agricultural sector of Pakistan in recent decades in the background of the changing role of the government and the encouragement of the private sector for investment in new ventures. These interventions have considerable GHG emission potential. Unfortunately, no published information is currently available on GHG concentrations in the Indus Basin to assess their magnitude and emission trends. The present study is an attempt to estimate GHG （CO2, CH4 and N2O） emissions arising from different agro-ecosystems of Indus Basin. The GHGs were estimated mostly using the IPCC Guidelines and data from the published literature. The results showed that CH4 emissions were the highest （4.126 Tg yr^-1） followed by N20 （0.265 Tg yr^-1） and CO2 （52.6 Tg yr^-1）. The sources of CH4 are enteric fermentation, rice cultivation and cultivation of other crops. N2O is formed by microbial denitrification of NO3 produced from applied fertilizer-N on cropped soils or by mineralization of native organic matter on fallow soils. CO2 is formed by the burning of plant residue and by soil respiration due to the decomposition of soil organic matter.
文摘Laser Induced Breakdown Spectroscopic(LIBS)technique was used to detect calcium and silicon in an unknown sample.In this method plasma was generated by Nd∶YAG laser of wavelength 1 064 nm with energy 400 mJ and pulse duration between 5~10ns.The method was applied for the qualitative as well as quantitative analysis.In the qualitative analysis,the electron number density(Ne)of plasma containing calcium and silicon is determined showing that Neof neutral particles is equivalent to 1016(cm-3)whereas for ionized particles it is 1017(cm-3).Plasma temperature is measured using Boltzmann plot method which must be greater than 10 000 k.Intensity ratio method is used for the quantitative analysis shows various elements in abundance with calcium and silicon in majority.
基金financially supported by the National Science Foundation of China(No.51471016)the Natural Science Foundation of Beijing(No.2151002)
文摘The oxidation resistance behavior of SmCo(2:17)-type high-temperature magnets modified with Ni-Cr two-layer coating was studied. The study depicts the mass gain kinetics and magnetic properties of uncoated and NiCr-modified magnets oxidized at high temperature(500 ℃) in air for 200 h. The oxidation test results illustrate that the mass gain of uncoated magnet is6.95 mg·cm^(-2) which is more than that(0.08 mg·cm^(-2)) of coated magnet after 200 h. For the magnetic properties concerned, there is a great loss for uncoated magnet, while for coated magnet, magnetic properties do not change much. The study of uncoated magnet through X-ray diffraction(XRD) and electron probe microanalysis(EPMA) shows that the invasion of oxygen at high temperature leads to the loss of magnetic properties by changing the microstructure of magnet.
文摘A comparative study on the prevalence of Anaplasma parasite was conducted on ticks carrying buffaloes and cattle. Five hundred blood samples of both animals (250 of each) were collected during February, March and April. Thin blood smears on glass slides were made, fixed in 100% methyl alcohol and examined. Microscopic examination revealed that 205 (41%) animals had Anaplasma parasites, out of which 89, 44 and 72 animals had Anaplasma marginale, Anaplasma centrale and mixed infection respectively. Infected buffaloes and cattle were 75 and 130 respectively. The infection in female was 53 and 92 in buffaloes and cattle respectively. Twenty-two and 92 blood samples of male were found positive in buffaloes and cattle respectively. Com- parative study revealed that the cattle were 26.82% more susceptible than buffaloes. The parasite prevailing percentage in female of both animals was slightly higher than that of the male. This investigation was aimed at studying the comparative prevalence of Anaplasma parasite in tick carrying buffaloes and cattle.
文摘The present study focuses on building a workflow for structural interpretation and velocity modeling and implementing to Jurassic-Cretaceous succession （Chiltan Limestone and Massive sand of the Lower Goru Formation）. 2D-Migrated seismic sections of the area are used as data set and in order to confirm the presence of hydrocarbons in the study area, P and S-wave seismic velocities are estimated from single-component seismic data. Some specific issues in the use of seismic data for modeling and hydrocarbon evaluation need to deal with including distinguishing the reservoir and cap rocks, and the effects of faults, folds and presence of hydrocarbons on these rocks. This study has carried out the structural interpretation and modeling of the seismic data for the identification of traps. The results demonstrate existence of appropriate structural traps in the form of horst and grabens in the area. 2D and 3D velocity modeling of the horizons indicates the presence of high velocity zones in the eastern half of the study while relatively low velocity zones are encountered in the western half of the area. Two wells were drilled in the study area （i.e. Fateh-01 and Ichhri-01） and both are dry. Immature hydrocarbons migration is considered as a failure reason for Fateh-01 and Ichhri-01 well.
文摘Some biologically important tin（Ⅳ） complexes derived from 5,5-diethyl sodium barbital have been synthesized and characterized through various analytical and spectroscopic techniques such as IR, ^1H-, ^13C-NMR and ^119mSn mossbauer. On the basis of these spectroscopic techniques, octahedral geometry has been assigned to all the novel compounds. These complexes, soluble in DMSO and DMF, were screened against a wide range of microorganisms. The results proved that the diphenyltin（Ⅳ） and dibutyltin（Ⅳ） complexes exhibit excellent activity against all types of microorganisms, while the rest of the compounds show significant activity that can be used during the biological study.
文摘The present paper represents the ethnopharmacological survey of Sudhan Gali,Kashmir,Pakistan.The study revealed that 12 plant species belonging to 11 families were used for the treatment of stomach,diabetes and ophthalmic diseases by the local people in Sudhan Gali.Achillea millefolium,Aconitum heterophyllum,Berberis lycium,Polygonum amplexicaule,Mentha longifolia,Paeonia emodi,Plantago lanceolata were locally used for stomach related problems treatment;Berberis lycium,Skimmia lareola,Solanum dulcamara for diabetes and Geranium wallichianum,Artemisia vulgaris,Solanum dulcamara,and Corydalis crassifolia used for the treatment of ophthalmic diseases.Two species Berberis lycium and Solanum dulcamara have multipurpose value.Former is used to treat stomach as well as diabetes while latter is used to treat not only to diabetes but also ophthalmic diseases.According to IUCN categories,out of these 12 plant species collected and marketed,Polygonum amplexicaule and Paeonia emodi are endangered,Aconitum heterophyllum;Berberis lycium species are vulnerable while Plantago lanceolata and Skimmia lareola species are rare.The availability of these medicinal plants has decreased during the past 20 years and these are facing a drastic biotic pressure due to their extensive usage and non-scientific methods of collection.It is quite evident that these valuable native medicinal plants species are going to decline in number and ultimately will become extinct if no timely proper conservation strategies are adopted.
文摘Five triorganotin（IV） （1-5） complexes of cinnamic acid, （Z）-2-acetamido-3-phenylacrylic acid, 3-methylbut-2-enoic acid, and 2,2-diphenylacetic acid have been synthesized and characterized by IH-13C-119Sn NMR, UV, and IR. The spectroscopic investigation demonstrated that the carboxylate group acts as a monodentate ligand in triorganotin（IV） compounds. Five triorganotin（IV） complexes were screened against the log phase culture of Mycobacterium tuberculosis H37Rv by colorimetric method using XTT dye as growth indicator. The MICs were found to he 0.08 and 1.25μg/mL.
文摘The present study deals with the depositional facies, diagenetic processes and sequence stratigraphy of the shallow marine carbonates of the Samana Suk Formation, Kohat Basin, in order to elucidate its reservoir quality. The Samana Suk Formation consists of thin to thick-bedded, oolitic, bioclastic, dolomitic and fractured limestone. Based on the integration of outcrop, petrographic and biofacies analyses, the unit is thought to have been deposited on a gentle homoclinal ramp in peritidal, lagoonal and carbonate shoal settings. Frequent variations in microfacies based sea-level curve have revealed seven Transgressive Systems Tracts(TSTs) and six Regressive Systems Tracts(RSTs). The unit has undergone various stages of diagenetic processes, including mechanical and chemical compaction, cementation,micritization, dissolution and dolomitization. The petrographic analyses show the evolution of porosity in various depositional and diagenetic phases. The fenestral porosity was mainly developed in peritidal carbonates during deposition,while the burial dissolution and diagenetic dolomitization have greatly enhanced the reservoir potential of the rock unit, as is further confirmed by the plug porosity and permeability analyses. The porosities and permeabilities were higher in shoal facies deposited in TSTs, as compared to lagoonal and peritidal facies, except for the dolomite in mudstone, deposited during RSTs. Hence good, moderate and poor reservoir potential is suggested for shoal, lagoonal and peritidal facies,respectively.
文摘In the present study, a co-culture technique was adopted with an aim to investigate a hyper production of exoglucanase, and β-glucosidase using cheap and easily available agro-industrial residue corn stover as growth supporting substrate. Various physio-chemical and nutritional variables were optimized using classical and completely randomized designs for induced production of exoglucanase, and β-glucosidase from the co-culture of Trichoderma viride and Ganoderma lucidum in solid state fermentation (SSF). Analysis profile showed that when the conditions of the SSF medium containing 15 g corn stover substrate (50% w/w moisture) inoculated with 6 mL of inoculum were optimal, the maximum productions of exoglucanase (485 ± 6.5 U/mL) and β-glucosidase (255 ± 3.3 U/mL) were recorded after 5 days of incubation at pH 6 and 35°C.
文摘The present paper addresses the megnetohydrodynamic Jeffrey fluid flow with heat and mass transfer on an infinitely rotating upright cone. Inquiry is carried out with heat source/sink and chemical reaction effects.Further, constant thermal and concentration flux situations are imposed. Optimal homotopy analysis method (OHAM) is employed to achieve series solutions of the concerned differential equations. Important results of the flow phenomena are explored and deliberated by means of graphs and numerical tables. It is perceived that thermal boundary layer thickness possess contrast variations for the heat source and heat sink, respectively. The chemical reaction enhances the heat transfer rate but decline the mass transfer rate. Moreover, the precision of the existing findings is verified by associating them with the previously available work.
文摘The differential cross section data for high energy K-p elastic scattering showing a break near-t=4(Gev/c)^(2) have been fitted for pL=20,100 and 200GeV/c with-t extended up to 14(Gev/c)^(2) by using a dipole pomeron mode.
文摘The inability of traditional privacy-preserving models to protect multiple datasets based on sensitive attributes has prompted researchers to propose models such as SLOMS,SLAMSA,(p,k)-Angelization,and(p,l)-Angelization,but these were found to be insufficient in terms of robust privacy and performance.(p,l)-Angelization was successful against different privacy disclosures,but it was not efficient.To the best of our knowledge,no robust privacy model based on fuzzy logic has been proposed to protect the privacy of sensitive attributes with multiple records.In this paper,we suggest an improved version of(p,l)-Angelization based on a hybrid AI approach and privacy-preserving approach like Generalization.Fuzz-classification(p,l)-Angel uses artificial intelligence based fuzzy logic for classification,a high-dimensional segmentation technique for segmenting quasi-identifiers and multiple sensitive attributes.We demonstrate the feasibility of the proposed solution by modelling and analyzing privacy violations using High-Level Petri Nets.The results of the experiment demonstrate that the proposed approach produces better results in terms of efficiency and utility.
基金the support from Chinese Academy of Science(CAS)TWAS for his Ph.D studies at the University of Science and Technology of China in the category of a 2016 CAS-TWAS President’s Fellowship Awardee(Series No.2016-172)+1 种基金partially supported by National Natural Science Foundation of China(Nos.41331067,41774169,and 41527804)the Key Research Program of Frontier Sciences,CAS(QYZDJ-SSW-DQC010)
文摘By performing one-dimensional particle-in-cell simulations, the nonlinear effects of electronacoustic(EA) waves are investigated in a multispecies plasma, whose constituents are hot electrons, cold electrons, and beam electrons with immobile neutralized positive ions. Numerical analyses have identified that EA waves with a sufficiently large amplitude tend to trap cold electrons. Because EA waves are dispersive, where the wave modes with different wavenumbers have different phase velocities, the trapping may lead to the mixing of cold electrons. The cold electrons finally get thermalized or heated. The investigation also shows that the excited EA waves give rise to a broad range of wave frequencies, which may be helpful for understanding the broadband-electrostatic-noise spectrum in the Earth’s auroral region.
文摘Gestational diabetes mellitus(GDM)is defined as any degree of glucose or carbohydrate intolerance mainly during pregnancy.About 10%to 15%of pregnancies are affected and complicated by gestational diabetes.Due to hormonal changes during pregnancy,the requirement for insulin increases,and thus the usual concentration of insulin previously catered for glycemic control is ineffective.In order to meet the body’s demand,the islet cells secrete a higher amount of insulin.GDM occurs when this higher concentration is also unable to control blood glucose.This increased resistance toward insulin is most noticeable during the third trimester of pregnancy,which gradually normalizes after the termination of pregnancy.Various complications do arise,which affect both the mother and her developing fetus.In the mother,miscarriages,delivery of baby via caesarian section,and other complications may result,whereas the fetus may be affected with congenital abnormalities,neonatal hypoglycemia,and even death.Treatment of GDM includes both non-pharmacological and pharmacological interventions.Pharmacological agents are employed when non-pharmacological interventions fail to achieve the desired target.Glyburide,insulin,and metformin are the commonly used pharmacological agents.
文摘This paper is about short review of earthquake statistics and efforts for earthquake mitigation, hazard and risk assessment studies in Pakistan. Pakistan and adjoining region lying between longitude 60°E to 78°E and latitude 20°N to 45°N are selected for the study as this region has a history of many large earthquakes because of its location in the region of intersection of three plates namely Indian, Eurasian and Arabian Sea plate. This paper is based on the study of both seismological history of the region which includes recent and historical seismicity based on earthquake catalogue as well as geological knowledge supplemented with available fault system information. In this study, Pakistan and adjoining regions are divided into 14 seismogenic zones. Seismicity of each zone is studied considering also the major cities in the respective zone and type of infrastructure which is mainly responsible for earthquake disaster rather than earthquake itself.
基金supported by the National Key R&D Program of China(2023YFF1205103),National Natural Science Foundation of China(81925034,22237005)the Key Research and Development Program of Ningxia Hui Autonomous Region(2022CMG01002)+1 种基金the Starry Night Science Fund of Zhejiang University Shanghai Institute for Advanced Study(SN-ZJU-SIAS-007)the innovative research team of high-level local universities in Shanghai(SHSMU-ZDCX20212700).
文摘The application of artificial intelligence(AI)in medicine,particularly through machine learning(ML),marked a significant progression in drug discovery.AI acts as a powerful catalyst in narrowing the gap between disease understanding and the identification of potential therapeutic agents.This review provides an inclusive summary of the latest advancements in AI and its application in drug discovery.We examine the various stages of the drug discovery process,starting from disease identification and encompassing diagnosis,target identification,screening,and lead discovery.AI's capability to analyze extensive datasets and discern patterns is essential in these stages,enhancing predictions and efficiencies in disease identification,drug discovery,and clinical trial management.The role of AI in expediting drug development is emphasized,highlighting its potential to analyze vast data volumes,thus reducing the time and costs associated with new drug market introduction.The importance of data quality,algorithm training,and ethical considerations,especially in patient data handling during clinical trials,is addressed.By considering these factors,AI promises to transform drug development,offering significant benefits to patients and society.
文摘The widespread presence of per-and polyfluoroalkyl substances(PFAS)in the environment poses a serious threat due to their persistent nature and harmful effects on human health and ecosystems.In this context,there is an imperative need for developing and improving methods to identify and eliminate these contaminants.Different detection techniques that are being used for PFAS detection are discussed.The details of detection mechanism of these techniques,their limitations and future areas of research for their optimization and improvement in detection efficiencies are also discussed in this review.Besides,this article provides a baseline for anticipating the advanced treatment technologies for PFAS in drinking water.We focus on the effectiveness of different removal techniques(physical,biological and chemical advancements)for eliminating various types of short and long chain PFAS.More so,the methods for the removal of PFAS are also explained with their limitations and future outlooks.Their pros and cons and limitations that need to be overcome and could be the potential future research.We included the recent literature and encompassed the information of PFAS related to guidelines,analytical techniques to determine PFAS and treatment or removal technologies.Conclusively,this study suggests that a combination of treatment methods will likely be necessary for effective PFAS remediation in water.
文摘The synthesis and in vitro antifungal activity of some Schiff bases and their Sn (Ⅳ) complexes has been tested against plant pathogenic fungi and it is found that they possess excellent fungicidal activity. On the basis of ^1H-, ^13C-,^119Sn NMR-, ^119Sn Mǒssbauer, IR and Elemental analysis the tetrahedral geometry is proposed for the synthesized compounds.
