Several studies report the problem of cardiovascular tolerance of treatments with neuroleptics, given the important number of morbidities in patients with mental illnesses. This preliminary work aimed to describe the ...Several studies report the problem of cardiovascular tolerance of treatments with neuroleptics, given the important number of morbidities in patients with mental illnesses. This preliminary work aimed to describe the epidemiological and biological profile of patients taking neuroleptics and followed in the psychiatry department of Brazzaville University Hospital, from the angle of cardiovascular risk. Fifty (50) patients (17 men and 33 women), with a mean age of 33.9 10.7 years, were included. Epidemiological data (sex, age, tobacco or alcohol consumption) were collected on pre-established survey forms. Biochemical (total cholesterol, HDL-c, triglycerides and atherogenicity index) and inflammatory parameters (ultra-sensitive CRP, troponin I and NT-ProBNP) were investigated using enzymatic and indirect immunofluorescence technical, respectively. The results obtained showed that 54% of patients were obese, 94% were non-smokers, and 12% had high blood pressure. 10% of patients had high total cholesterol levels and 90% had HDL cholesterol levels below 60 mg/dl. Triglycerides and atherogenicity index were significantly elevated in relation to Body Mass Index (BMI). Ultrasensitive CRP was elevated in 38% of patients. In conclusion, this study revealed an association between lipid parameters (triglycerides and atherogenicity index) in relation to BMI in patients taking neuroleptics followed in the Psychiatry Department of University Hospital Center of Brazzaville.展开更多
Objective:To investigate the differences in childhood trauma and life events between adolescents with depression and healthy controls,and to analyze the correlations between these factors and depressive symptoms.As su...Objective:To investigate the differences in childhood trauma and life events between adolescents with depression and healthy controls,and to analyze the correlations between these factors and depressive symptoms.As such,we aim to provide theoretical foundations for early identification and intervention.Methods:This cross-sectional study enrolled 90 hospitalized adolescents with depression(case group)and 91 healthy adolescents(control group).Childhood Trauma Questionnaire(CTQ),Adolescent Self-Rating Life Events Checklist(ASLEC),and Children’s Depression Inventory(CDI)were administered to assess trauma history,life event stressors,and depressive symptoms.Statistical analyses included independent samples t-tests,chi-square tests,and Pearson correlation analysis.Results:The case group demonstrated a significantly higher proportion of only-child families(28.9%).ASLEC and CDI scores were significantly elevated in the case group compared to the control group(P<0.05).In comparison,CTQ scores were lower in the case group(P=0.025).Positive correlations were identified between CDI scores and both CTQ(r=0.261)and ASLEC(r=0.218)in the case group.Conclusion:Child-hood trauma and recent life event stressors demonstrate significant associations with adolescent depressive symp-toms,potentially mediated through emotional dysregulation and negative cognitive bias.Implementation of early trauma screening protocols combined with stress management interventions(e.g.,cognitive behavioral therapy)and family system optimization strategies may effectively mitigate depression risk in this population.展开更多
Objectives: To determine the level of adversity quotient and its associations with rumination, optimism, and authoritative parenting style in junior high school students. Adversity quotient is the adaptation ability t...Objectives: To determine the level of adversity quotient and its associations with rumination, optimism, and authoritative parenting style in junior high school students. Adversity quotient is the adaptation ability to overcome problems and obstacles with a positive attitude. Early adolescence, as a critical stage of life, needs to cultivate adversity quotient. However, adversity quotient and its influencing factors in adolescents have not been fully understood. Methods: A total of 129 students from 3 junior high schools (grade 7-9) in Chon Buri province, Thailand, were randomly recruited to participate in this correlational research study. They completed 5 questionnaires including the demographic form, adversity quotient assessment, authoritative parenting style, optimism, and rumination. Descriptive statistics and Pearson’s correlation coefficient were used for data analysis. Results: Adversity quotient was at a moderate level with a mean of 138.78 (standard deviation [SD] = 21.25). Adversity quotient was significantly, positively correlated with authoritative parenting at the highest level (r = 0.60), followed by optimism at a moderate level (r = 0.38), and rumination at a low level (r = 0.25, P < 0.01). Conclusions: All parties responsible for early adolescents’ development should enhance the adversity quotient to a higher level through campaigns promoting authoritative parenting and optimism. An unexpected positive correlation between adversity quotient and rumination warrants cautious interpretation and more studies.展开更多
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by multisystemic involvement and diverse manifestations. Neuropsychiatric systemic lupus erythematosus (NPSLE) is a complex neurological...Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by multisystemic involvement and diverse manifestations. Neuropsychiatric systemic lupus erythematosus (NPSLE) is a complex neurological disorder characterized by neuropsychological dysfunction. NPSLE is associated with increased morbidity and mortality. In 1999, the American College of Rheumatology developed 19 discrete neuropsychiatric syndromes that comprised NPSLE. Nervous system disease in systemic lupus erythematosus is manifested by a wide variety of clinical manifestations. The pathogenesis of NPSLE is due to autoantibodies, neuronal and non neuronal antigens and the generation of proinflammatory cytokines and mediators. Anatomopathological lesions are attributed to in situ thrombosis, edema, hemorrhage, vasculitis, atherosclerosis or atheroembolism. The diagnosis of NPSLE remains largely one of exclusion and is approached by clinical evaluation, and supported when necessary by autoantibody profiles, diagnostic imaging, electrophysiologic studies and objective assessment of cognitive performance. Brain MRI abnormalities in NPSLE might show small punctate focal lesions in white matter being the most common MRI finding, followed by cortical atrophy, ventricular dilation, cerebral edema, diffuse white matter abnormalities, focal atrophy, cerebral infarction, acute leukoencephalopathy and intracranial hemorrhage. The treatment is based on the use of symptomatic therapies, immunosuppressives and non-pharmacologic interventions. This review paper was designed to understand the pathophysiology for better management of NPSLE.展开更多
AIM: To estimate if and to what extent long acting octreotide (LAR) improves survival and quality of life in patients with advanced hepatocellular carcinoma (HCC). METHODS: A total of 127 cirrhotics, stages A-B, due t...AIM: To estimate if and to what extent long acting octreotide (LAR) improves survival and quality of life in patients with advanced hepatocellular carcinoma (HCC). METHODS: A total of 127 cirrhotics, stages A-B, due to chronic viral infections and with advanced HCC, were enrolled in the study. Scintigraphy with 111Indium labeled octreotide was performed in all cases. The patients with increased accumulation of radionuclear compound were randomized to receive either oral placebo only or octreotide/octreotide LAR only as follows: octreotide 0.5mg s.c. every 8 h for 6 wk, at the end of wk 4-8 octreotide LAR 20 mg i.m. and at the end of wk 12 and every 4 wk octreotide LAR 30mg i.m.. Follow-up was worked out monthly as well as the estimation of quality of life (QLQ-C30 questionnaire). Patients with negative somatostatin receptors (SSTR) detection were followed up in the same manner. RESULTS: Scintigraphy demonstrated SSTR in 61 patients. Thirty were randomized to receive only placebo and 31 only octreotide. A significantly higher survival time was observed for the octreotide group (49 ± 6 wk) as compared to the control group (28 ± 1 wk) and to the SSTR negative group (28 ± 2 wk), LR = 20.39, df = 2, P < 0.01. The octreotide group presented 68.5% lower hazard ratio [95% CI (47.4%-81.2%)]. During the f irst year, a 22%, 39% and 43% decrease in the QLQ-C30 score was observed in each group respectively.CONCLUSION: The proposed therapeutic approach has shown to improve the survival and quality of life in SSTR positive patients with advanced HCC.展开更多
Background The Developmental, Individual-differences, Relationship-based model(DIR/Floortime) is one of the well-known therapies for autism spectrum disorder(ASD), in which its main principle is to promote holistic de...Background The Developmental, Individual-differences, Relationship-based model(DIR/Floortime) is one of the well-known therapies for autism spectrum disorder(ASD), in which its main principle is to promote holistic development of an individual and relationships between the caregivers and children. Parental engagement is an essential element to DIR/Floortime treatment and involved with various factors. Finding those supporting factors and eliminating factors that might be an obstacle for parental engagement are essential for children with ASD to receive the full benefits of treatment.Aim To examine the association between parents, children and provider and service factors with parental engagement in DIR/Floortime treatment.Methods This is a cross-sectional study of parents with children aged 2–12 years who were diagnosed with ASD. Data were collected using a parent, child, provider and service factors questionnaire. Patient Health Questionaire-9, Clinical Global Impressions-Severity and Childhood Autism Rating Scale were also used to collect data. For parent engagement in DIR/Floortime, we evaluated quality of parental engagement in DIR/Floortime and parent application of DIR/Floortime techniques at home. Finally, Clinical Global Impressions-Improvement and Functional Emotional Developmental Level were used to assess child development.Results Parents who were married, had lower income and higher knowledge of DIR/Floortime theory were more likely to have higher parent engagement(χ2=4.43, p=0.035; χ2=13.1, p<0.001 and χ2=4.06, p=0.044 respectively). Furthermore, severity of the diagnosis and the continuation of the treatment significantly correlated with parent engagement(χ2=5.83, p=0.016 and χ2=4.72, p=0.030 respectively). It was found that parents who applied the techniques for more than 1 hour/day, or had a high-quality parent engagement, significantly correlated with better improvement in child development(t=-2.03, p=0.049; t=-2.00, p=0.053, respectively).Conclusion Factors associated with parents, children, and provider and service factors had a significant correlation with parent engagement in DIR/Floortime in which children whose parents had more engagement in DIR/Floortime techniques had better improvement in child development.展开更多
Background:It is obvious that hemodialysis is a stressful process,leading to numerous social and psychological problems,and may cause fatigue and helplessness.Objective:This study aimed to explain the experiences of h...Background:It is obvious that hemodialysis is a stressful process,leading to numerous social and psychological problems,and may cause fatigue and helplessness.Objective:This study aimed to explain the experiences of hemodialysis clients regarding the effect of psychological problems on fatigue.Methods:This article was extracted from a qualitative study conducted on clients undergoing hemodialysis in Khorramabad.To this end,a total of 15 participants were purposefully selected using the snowball sampling method and the required data was collected using individual,face to face,detailed and semi-structured interviews.There were 12 client interviewees and one doctor,one nurse and one hemodialysis client's spouse.Content analysis was used to analyze the data.Results:Continuous analysis of data and documents obtained from the interviews on the hemodialysis clients'experiences and comments regarding the main causes of fatigue revealed two main categories:1)Psychological effects with subcategories of psychological stress and exhaustion;2)Needs and constraints with subcategories of individual and social needs and constraints.Conclusion:According to the clients'speech and expression analysis,psychological impacts and disease-induced needs and constraints were the most important cause of fatigue and its continuation among these clients.展开更多
Few-shot Learning algorithms can be effectively applied to fields where certain categories have only a small amount of data or a small amount of labeled data,such as medical images,terrorist surveillance,and so on.The...Few-shot Learning algorithms can be effectively applied to fields where certain categories have only a small amount of data or a small amount of labeled data,such as medical images,terrorist surveillance,and so on.The Metric Learning in the Few-shot Learning algorithmis classified by measuring the similarity between the classified samples and the unclassified samples.This paper improves the Prototypical Network in the Metric Learning,and changes its core metric function to Manhattan distance.The Convolutional Neural Network of the embedded module is changed,and mechanisms such as average pooling and Dropout are added.Through comparative experiments,it is found that thismodel can converge in a small number of iterations(below 15,000 episodes),and its performance exceeds algorithms such asMAML.Research shows that replacingManhattan distance with Euclidean distance can effectively improve the classification effect of the Prototypical Network,and mechanisms such as average pooling and Dropout can also effectively improve the model.展开更多
Background:Elderly people with depression require special care and attention.However,nostalgia is a complex emotional situation for a person who recalls the missing past.To improve mental health,quality of life,and at...Background:Elderly people with depression require special care and attention.However,nostalgia is a complex emotional situation for a person who recalls the missing past.To improve mental health,quality of life,and attitudes toward aging in institutional care,group nostalgia therapy can be a nursing intermediary for the elderly.This study aimed to analyze the effect of group nostalgia therapy on quality of life cognitive function in elderly patients with depression.Methods:A total of 89 participants were enrolled in this study,which was further categorized into a control(n=40)and a nostalgia therapy group(n=49).A standard questionnaire was used to compare the QoL,MMSE and GDS scores between the control and the nostalgia therapy groups.Results:Neither the nostalgia group nor the control group showed any statistical difference based on the patient characteristics,and both groups had a homogeneous distribution with p<0.05.However,in the intervention with nostalgia therapy,the therapy group showed improvements in almost all four domains of quality of life:physical health,psychological,environmental and social well-being.Moreover,the standard regression residual plot observed that both the post-test scores of MMSE and GDS showed favorable scores with respect to WHO-QoL.Conclusion:The study observed that group nostalgia therapy helps improve the quality of life and cognitive function in elderly patients with depression.The study also concludes that reducing depressive symptoms through nostalgia therapy could improve all four domains of the WHOQoL BREF.展开更多
Objective:Maintaining blood pressure(BP)could improve the quality of life among farmers in agricultural health.The study aims to evaluate the effects of progressive muscular relaxation and stretching exercises(SEs)for...Objective:Maintaining blood pressure(BP)could improve the quality of life among farmers in agricultural health.The study aims to evaluate the effects of progressive muscular relaxation and stretching exercises(SEs)for BP in farmer subjects in rural areas.Methods:A randomized controlled design was applied for this study.We performed a method,which is the combination of progressive muscle relaxation(PMR)and SEs for participants(30 in the control group and 60 in the intervention group).The intervention group self-practiced PMR and SEs through a video that providing instructions for 15 min.PMR practiced before going to sleeping in the night,and SEs practiced before going to farms in the morning per day for 3-months.Wilcoxon signed-rank test was performed to measure the difference between systolic blood pressure(SBP)and diastolic blood pressure(DBP)as one pre-and post-test comparison of baseline and 3 months data in control and intervention groups.Results:There were no significant differences between SBP and DBP pre-and post-test in control group(P>0.050).Meanwhile,there were significant differences in reducing SBP(M=126.67;SD=18.07;95%CI=120-147.5 mmHg)and DBP(M=80.67;SD=6.91;95%CI=80-90 mmHg)pre-and post-test combination of PMR and SEs in intervention group(P<0.001).After 3-months of follow-up data,number type SBP and DBP still remained at the same levels of baseline and 3-month data in control group.While,there was an increased number of normal and prehypertension for SBP and DBP(10%vs.10%and 20%vs.31.6%)and reduced of hypertension stage I for SBP and DBP(30%vs.41.6%).Conclusions:This pilot study demonstrated effectively to reduce SBP and DBP among farmers using the combination of PMR and SEs in the agricultural health setting.展开更多
OBJECTIVE To identify risk factors for relapse and death in patients with T1 to T2 breast cancer with 0-3 positive axillary lymph nodes.METHODS The case files of 540 breast cancer patients with T1-T2 tumors with 0-3 p...OBJECTIVE To identify risk factors for relapse and death in patients with T1 to T2 breast cancer with 0-3 positive axillary lymph nodes.METHODS The case files of 540 breast cancer patients with T1-T2 tumors with 0-3 positive nodes were reviewed retrospectively. Ten-year locoregional recurrence （LRR）, distant recurrence （DR）, disease-free survival （DFS） and overall survival （OS） of the patients were analyzed. Univariate statistical analysis and Cox proportional hazards models were carried out with SPSS so ware v.16.0.RESULTS The median follow-up of all the patients was 7.2 years. On multivariate analysis, 〉 20% positive axillary nodes was the only variable that influenced LRR adversely （hazard ratio[HR], 12.816; 95% confidence interval, 4.657-35.266, P 〈 0.001）; 〉 20% positive axillary nodes and ductal carcinoma were variables that influenced DR adversely （HR, 11.088, 95% confidence interval, 3.807-32.297, P 〈 0.001; HR, 0.390, 95% confidence interval, 0.179-0.851, P = 0.018）; 1-3 positive axillary nodes and 〉 20% positive axillary nodes were the only variables that had negative e. ect on 10-year OS （HR, 2.110, 95% confi dence interval, 1.364-3.264, P = 0.001; HR, 10.244, 95% confidence interval, 3.497-30.011, P 〈 0.001） and they were also adverse prognostic variables on 10-year DFS （HR, 1.634, 95% confidence interval, 1.171-2.279, P = 0.004; HR, 7.339, 95% confi dence interval,2.906-18.530, P 〈 0.001）.CONCLUSION Axillary lymph nodal status is the only risk factor with a signifi cant impact on 10-year LRR, DR, OS and DFS.Patients with T1-T2 breast cancer with 0-3 positive lymph nodes have the LRR and DR of over 10 years, and the OS and DFS of less than 10 years, compared to patients with negative lymph nodes.Histology in primary tumors is a signifi cant prognostic factor for the 10-year DR.展开更多
Background: Assessment of healthcare students’ mental health problems is an important aspect of health promotion. This study examined the roles of moral intelligence (MI) and identity styles in prediction of mental h...Background: Assessment of healthcare students’ mental health problems is an important aspect of health promotion. This study examined the roles of moral intelligence (MI) and identity styles in prediction of mental health problems in healthcare students. Methods: In a correlation study, two hundred healthcare students (100 girls, 100 boys) of Medicine, Density, and Paramedicine Colleges of Bobol University of Medical Sciences were selected. The subjects filled out three questionnaires;General Health Questionnaire (GHQ-28), Moral Competency Inventory (MCI), and Identity Style Inventory (ISI), and General Health Questionnaire (GHQ-28). Pearson correlation, multivariate analysis variance model (MANOVA), and multivariate regression used to analyze the data. Results: Boys and girls did not have a meaningful difference in the mean of total GHQ, MCI, normative and informational identity. Girls had significantly higher mean level of diffused-avoidant identity than boys. There was a positive and significant relationship between moral intelligence, normative identity and mental health problems of students. Also, there was a negative relationship (p < 0.05) between diffused-avoidant identity and mental health problems of students. Moral intelligence, informational and normative identity predicted 25.8% of the variance in mental health problems for girls’ students. Normative and diffused-avoidant identity predicted 21.6% of the variance in mental health problems for girls’ students. Conclusions: This study demonstrated that moral intelligence and identity status contributed to the mental health problems of healthcare students. University administrators should adopt strategies that strengthen the moral intelligence and identity maturity associated with university students’ mental health.展开更多
<strong>Background:</strong> Ictal psychosis without remarkable cognitive impairment is uncommon occurrence, presents diagnostic challenges to clinicians, often misdiagnosed as functional psychosis. <st...<strong>Background:</strong> Ictal psychosis without remarkable cognitive impairment is uncommon occurrence, presents diagnostic challenges to clinicians, often misdiagnosed as functional psychosis. <strong>Case Presentation:</strong> We present 3 cases of young adult men admitted to psychiatric ward as functional psychosis. They presented with irritability, physical aggression and mild cognitive impairment with intense emotional symptoms, and persecutory ideas and delusions. Two were wrongly diagnose as mania while the third was mimicking schizophrenia in its presentation. They received antipsychotic treatment and misdiagnosed as functional psychosis. They did not respond well to such treatment, until, series electroencephalograms were taken which revealed evidence of ictal psychosis. All, thence, responded well to addition of antiepileptic treatment. This, not only, proves to be effective, but also determined future management and prognosis. <strong>Conclusion: </strong>These cases shine light onto the role of the frontal cortex in the genesis of quasi-manic episodes and highlight the importance of EEG investigations in first episode of acute psychosis.展开更多
BACKGROUND The coronavirus disease 2019(COVID-19)epidemic disrupted education systems by forcing systems to shift to emergency online leaning.Online learning satisfaction affects academic achievement.Many factors affe...BACKGROUND The coronavirus disease 2019(COVID-19)epidemic disrupted education systems by forcing systems to shift to emergency online leaning.Online learning satisfaction affects academic achievement.Many factors affect online learning satisfaction.However there is little study focused on personal characteristics,mental status,and coping style when college students participated in emergency online courses.regression analyses were performed to identify factors that affected online learning satisfaction.RESULTS Descriptive findings indicated that 62.9%(994/1580)of students were satisfied with online learning.Factors that had significant positive effects on online learning satisfaction were online learning at scheduled times,strong exercise intensity,good health,regular schedule,focusing on the epidemic less than one hour a day,and maintaining emotional stability.Positive coping styles were protective factors of online learning satisfaction.Risk factors for poor satisfaction were depression,neurasthenia,and negative coping style.CONCLUSION College students with different personal characteristics,mental status,and coping style exhibited different degrees of online learning satisfaction.Our findings provide reference for educators,psychologists,and school adminis-trators to conduct health education intervention of college students during emergency online learning.展开更多
The most stigmatized among all diseases are mental illness such as schizophrenia, both for the children themselves and for their families. The present study aims in the recording of the problems and needs of children ...The most stigmatized among all diseases are mental illness such as schizophrenia, both for the children themselves and for their families. The present study aims in the recording of the problems and needs of children with schizophrenia at school and identification of actions that contribute to addressing their problems; The material of study consists of recent articles concerning the subject that were found mainly in the Medline electronic database, the HEAL-Link （Hellenic Academic Libraries Link） and in the Google Scholar search engine; The school community, due to the weakness of understanding the thoughts and behavior of schizophrenic children, in conjunction with the stress of thought of this mental illness, are shaping the development of social stigma. The co-operation of mental health educators and school organizations in general is required in order to improve attitudes towards these children and students should be aware of an open world, without prejudice. The alienation of children with schizophrenia from the school community becomes a barrier to contact and collaboration with their peers. With proper education about mentally ill children teachers can remove the stigma from them.展开更多
Introduction: The essential problems in providing quality and safety services to patients, rapid changes in health care settings as well as information technology require educational revision. Competency-based curricu...Introduction: The essential problems in providing quality and safety services to patients, rapid changes in health care settings as well as information technology require educational revision. Competency-based curriculum focuses on set of skills that students should achieve. This study reviewed characteristics of competency-based curriculum in psychiatric nursing. Methods: A literature review about a competency-based curriculum in psychiatric mental health nursing was carried out by searching databases including Iran Medex, Iran Doc, and Pub Med with key words such as competency-based education, competency-based curriculum, and competency-based curriculum in psychiatric mental health nursing. No time limitation was considered. Results: Results revealed that over 30 literatures have been done about nursing curriculum, but just several studies were done regarding competency-based curriculum and just a few about competency-based curriculum in psychiatric mental health nursing. Conclusion: Competency-based curriculum development is one of the essential steps to facilitate teaching-learning process. The revision of curriculum may decrease theory-practice gap and pave the way for graduates to have essential competences for their roles.展开更多
The Clinical Strategies Implementation scale (CSI) was originally designed to be used by external reviewers in order to measure the extent to which evidence-based strategies had been implemented in the treatment of pe...The Clinical Strategies Implementation scale (CSI) was originally designed to be used by external reviewers in order to measure the extent to which evidence-based strategies had been implemented in the treatment of persons with schizophrenia spectrum disorders according to Resource-group Assertive Community Treatment (RACT). The present investigation had two aims: 1) to conduct a revision of CSI and to examine the revised instrument (CSI-R) in terms of interrater reliability (Study I);2) to compare assessments of CSI-R made by experienced assessors with assessments made by students in case management (Study II) in order to determine whether the instrument has validity even when more inexperienced persons are using it. In Study I six raters, who took part in 12 to 15 cases from three outpatient community mental health teams, participated. Results indicated that internal consistency of the CSI-R was strong (alpha = 0.89) as well as correlations between individual raters’ (r between 0.80-0.98). In Study II 91 newly trained RACT praxis trainees participated. Each of them followed one case for eighteen months, i.e., the client which they had been assigned during training (n = 91). The five external auditors in the education program then independently assessed the 91 cases with the CSI-R. Results showed significant correlations between experts and trainees (rho = 0.68,展开更多
文摘Several studies report the problem of cardiovascular tolerance of treatments with neuroleptics, given the important number of morbidities in patients with mental illnesses. This preliminary work aimed to describe the epidemiological and biological profile of patients taking neuroleptics and followed in the psychiatry department of Brazzaville University Hospital, from the angle of cardiovascular risk. Fifty (50) patients (17 men and 33 women), with a mean age of 33.9 10.7 years, were included. Epidemiological data (sex, age, tobacco or alcohol consumption) were collected on pre-established survey forms. Biochemical (total cholesterol, HDL-c, triglycerides and atherogenicity index) and inflammatory parameters (ultra-sensitive CRP, troponin I and NT-ProBNP) were investigated using enzymatic and indirect immunofluorescence technical, respectively. The results obtained showed that 54% of patients were obese, 94% were non-smokers, and 12% had high blood pressure. 10% of patients had high total cholesterol levels and 90% had HDL cholesterol levels below 60 mg/dl. Triglycerides and atherogenicity index were significantly elevated in relation to Body Mass Index (BMI). Ultrasensitive CRP was elevated in 38% of patients. In conclusion, this study revealed an association between lipid parameters (triglycerides and atherogenicity index) in relation to BMI in patients taking neuroleptics followed in the Psychiatry Department of University Hospital Center of Brazzaville.
基金Research Project of Yunnan Provincial Psychiatric Hospital(SJKY-2023-10).
文摘Objective:To investigate the differences in childhood trauma and life events between adolescents with depression and healthy controls,and to analyze the correlations between these factors and depressive symptoms.As such,we aim to provide theoretical foundations for early identification and intervention.Methods:This cross-sectional study enrolled 90 hospitalized adolescents with depression(case group)and 91 healthy adolescents(control group).Childhood Trauma Questionnaire(CTQ),Adolescent Self-Rating Life Events Checklist(ASLEC),and Children’s Depression Inventory(CDI)were administered to assess trauma history,life event stressors,and depressive symptoms.Statistical analyses included independent samples t-tests,chi-square tests,and Pearson correlation analysis.Results:The case group demonstrated a significantly higher proportion of only-child families(28.9%).ASLEC and CDI scores were significantly elevated in the case group compared to the control group(P<0.05).In comparison,CTQ scores were lower in the case group(P=0.025).Positive correlations were identified between CDI scores and both CTQ(r=0.261)and ASLEC(r=0.218)in the case group.Conclusion:Child-hood trauma and recent life event stressors demonstrate significant associations with adolescent depressive symp-toms,potentially mediated through emotional dysregulation and negative cognitive bias.Implementation of early trauma screening protocols combined with stress management interventions(e.g.,cognitive behavioral therapy)and family system optimization strategies may effectively mitigate depression risk in this population.
基金supported by the Faculty of Nursing Burapha University(No.19/2561).
文摘Objectives: To determine the level of adversity quotient and its associations with rumination, optimism, and authoritative parenting style in junior high school students. Adversity quotient is the adaptation ability to overcome problems and obstacles with a positive attitude. Early adolescence, as a critical stage of life, needs to cultivate adversity quotient. However, adversity quotient and its influencing factors in adolescents have not been fully understood. Methods: A total of 129 students from 3 junior high schools (grade 7-9) in Chon Buri province, Thailand, were randomly recruited to participate in this correlational research study. They completed 5 questionnaires including the demographic form, adversity quotient assessment, authoritative parenting style, optimism, and rumination. Descriptive statistics and Pearson’s correlation coefficient were used for data analysis. Results: Adversity quotient was at a moderate level with a mean of 138.78 (standard deviation [SD] = 21.25). Adversity quotient was significantly, positively correlated with authoritative parenting at the highest level (r = 0.60), followed by optimism at a moderate level (r = 0.38), and rumination at a low level (r = 0.25, P < 0.01). Conclusions: All parties responsible for early adolescents’ development should enhance the adversity quotient to a higher level through campaigns promoting authoritative parenting and optimism. An unexpected positive correlation between adversity quotient and rumination warrants cautious interpretation and more studies.
文摘Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by multisystemic involvement and diverse manifestations. Neuropsychiatric systemic lupus erythematosus (NPSLE) is a complex neurological disorder characterized by neuropsychological dysfunction. NPSLE is associated with increased morbidity and mortality. In 1999, the American College of Rheumatology developed 19 discrete neuropsychiatric syndromes that comprised NPSLE. Nervous system disease in systemic lupus erythematosus is manifested by a wide variety of clinical manifestations. The pathogenesis of NPSLE is due to autoantibodies, neuronal and non neuronal antigens and the generation of proinflammatory cytokines and mediators. Anatomopathological lesions are attributed to in situ thrombosis, edema, hemorrhage, vasculitis, atherosclerosis or atheroembolism. The diagnosis of NPSLE remains largely one of exclusion and is approached by clinical evaluation, and supported when necessary by autoantibody profiles, diagnostic imaging, electrophysiologic studies and objective assessment of cognitive performance. Brain MRI abnormalities in NPSLE might show small punctate focal lesions in white matter being the most common MRI finding, followed by cortical atrophy, ventricular dilation, cerebral edema, diffuse white matter abnormalities, focal atrophy, cerebral infarction, acute leukoencephalopathy and intracranial hemorrhage. The treatment is based on the use of symptomatic therapies, immunosuppressives and non-pharmacologic interventions. This review paper was designed to understand the pathophysiology for better management of NPSLE.
文摘AIM: To estimate if and to what extent long acting octreotide (LAR) improves survival and quality of life in patients with advanced hepatocellular carcinoma (HCC). METHODS: A total of 127 cirrhotics, stages A-B, due to chronic viral infections and with advanced HCC, were enrolled in the study. Scintigraphy with 111Indium labeled octreotide was performed in all cases. The patients with increased accumulation of radionuclear compound were randomized to receive either oral placebo only or octreotide/octreotide LAR only as follows: octreotide 0.5mg s.c. every 8 h for 6 wk, at the end of wk 4-8 octreotide LAR 20 mg i.m. and at the end of wk 12 and every 4 wk octreotide LAR 30mg i.m.. Follow-up was worked out monthly as well as the estimation of quality of life (QLQ-C30 questionnaire). Patients with negative somatostatin receptors (SSTR) detection were followed up in the same manner. RESULTS: Scintigraphy demonstrated SSTR in 61 patients. Thirty were randomized to receive only placebo and 31 only octreotide. A significantly higher survival time was observed for the octreotide group (49 ± 6 wk) as compared to the control group (28 ± 1 wk) and to the SSTR negative group (28 ± 2 wk), LR = 20.39, df = 2, P < 0.01. The octreotide group presented 68.5% lower hazard ratio [95% CI (47.4%-81.2%)]. During the f irst year, a 22%, 39% and 43% decrease in the QLQ-C30 score was observed in each group respectively.CONCLUSION: The proposed therapeutic approach has shown to improve the survival and quality of life in SSTR positive patients with advanced HCC.
文摘Background The Developmental, Individual-differences, Relationship-based model(DIR/Floortime) is one of the well-known therapies for autism spectrum disorder(ASD), in which its main principle is to promote holistic development of an individual and relationships between the caregivers and children. Parental engagement is an essential element to DIR/Floortime treatment and involved with various factors. Finding those supporting factors and eliminating factors that might be an obstacle for parental engagement are essential for children with ASD to receive the full benefits of treatment.Aim To examine the association between parents, children and provider and service factors with parental engagement in DIR/Floortime treatment.Methods This is a cross-sectional study of parents with children aged 2–12 years who were diagnosed with ASD. Data were collected using a parent, child, provider and service factors questionnaire. Patient Health Questionaire-9, Clinical Global Impressions-Severity and Childhood Autism Rating Scale were also used to collect data. For parent engagement in DIR/Floortime, we evaluated quality of parental engagement in DIR/Floortime and parent application of DIR/Floortime techniques at home. Finally, Clinical Global Impressions-Improvement and Functional Emotional Developmental Level were used to assess child development.Results Parents who were married, had lower income and higher knowledge of DIR/Floortime theory were more likely to have higher parent engagement(χ2=4.43, p=0.035; χ2=13.1, p<0.001 and χ2=4.06, p=0.044 respectively). Furthermore, severity of the diagnosis and the continuation of the treatment significantly correlated with parent engagement(χ2=5.83, p=0.016 and χ2=4.72, p=0.030 respectively). It was found that parents who applied the techniques for more than 1 hour/day, or had a high-quality parent engagement, significantly correlated with better improvement in child development(t=-2.03, p=0.049; t=-2.00, p=0.053, respectively).Conclusion Factors associated with parents, children, and provider and service factors had a significant correlation with parent engagement in DIR/Floortime in which children whose parents had more engagement in DIR/Floortime techniques had better improvement in child development.
基金This work is a part of Master dissertation in psychiatric nursing done by Zahra Rezaee and was financially supported by Kermanshah University of Medical Sciences grants No.95235.
文摘Background:It is obvious that hemodialysis is a stressful process,leading to numerous social and psychological problems,and may cause fatigue and helplessness.Objective:This study aimed to explain the experiences of hemodialysis clients regarding the effect of psychological problems on fatigue.Methods:This article was extracted from a qualitative study conducted on clients undergoing hemodialysis in Khorramabad.To this end,a total of 15 participants were purposefully selected using the snowball sampling method and the required data was collected using individual,face to face,detailed and semi-structured interviews.There were 12 client interviewees and one doctor,one nurse and one hemodialysis client's spouse.Content analysis was used to analyze the data.Results:Continuous analysis of data and documents obtained from the interviews on the hemodialysis clients'experiences and comments regarding the main causes of fatigue revealed two main categories:1)Psychological effects with subcategories of psychological stress and exhaustion;2)Needs and constraints with subcategories of individual and social needs and constraints.Conclusion:According to the clients'speech and expression analysis,psychological impacts and disease-induced needs and constraints were the most important cause of fatigue and its continuation among these clients.
文摘Few-shot Learning algorithms can be effectively applied to fields where certain categories have only a small amount of data or a small amount of labeled data,such as medical images,terrorist surveillance,and so on.The Metric Learning in the Few-shot Learning algorithmis classified by measuring the similarity between the classified samples and the unclassified samples.This paper improves the Prototypical Network in the Metric Learning,and changes its core metric function to Manhattan distance.The Convolutional Neural Network of the embedded module is changed,and mechanisms such as average pooling and Dropout are added.Through comparative experiments,it is found that thismodel can converge in a small number of iterations(below 15,000 episodes),and its performance exceeds algorithms such asMAML.Research shows that replacingManhattan distance with Euclidean distance can effectively improve the classification effect of the Prototypical Network,and mechanisms such as average pooling and Dropout can also effectively improve the model.
基金funded by Longyan Science and Technology Innovation Joint Fund Health Project(2021LYF17053).
文摘Background:Elderly people with depression require special care and attention.However,nostalgia is a complex emotional situation for a person who recalls the missing past.To improve mental health,quality of life,and attitudes toward aging in institutional care,group nostalgia therapy can be a nursing intermediary for the elderly.This study aimed to analyze the effect of group nostalgia therapy on quality of life cognitive function in elderly patients with depression.Methods:A total of 89 participants were enrolled in this study,which was further categorized into a control(n=40)and a nostalgia therapy group(n=49).A standard questionnaire was used to compare the QoL,MMSE and GDS scores between the control and the nostalgia therapy groups.Results:Neither the nostalgia group nor the control group showed any statistical difference based on the patient characteristics,and both groups had a homogeneous distribution with p<0.05.However,in the intervention with nostalgia therapy,the therapy group showed improvements in almost all four domains of quality of life:physical health,psychological,environmental and social well-being.Moreover,the standard regression residual plot observed that both the post-test scores of MMSE and GDS showed favorable scores with respect to WHO-QoL.Conclusion:The study observed that group nostalgia therapy helps improve the quality of life and cognitive function in elderly patients with depression.The study also concludes that reducing depressive symptoms through nostalgia therapy could improve all four domains of the WHOQoL BREF.
基金the Ministry of Research,Technology,and Higher Education(KEMENRISTEK-DIKTI)for Hibah Bersaing Grant 2015-2016.
文摘Objective:Maintaining blood pressure(BP)could improve the quality of life among farmers in agricultural health.The study aims to evaluate the effects of progressive muscular relaxation and stretching exercises(SEs)for BP in farmer subjects in rural areas.Methods:A randomized controlled design was applied for this study.We performed a method,which is the combination of progressive muscle relaxation(PMR)and SEs for participants(30 in the control group and 60 in the intervention group).The intervention group self-practiced PMR and SEs through a video that providing instructions for 15 min.PMR practiced before going to sleeping in the night,and SEs practiced before going to farms in the morning per day for 3-months.Wilcoxon signed-rank test was performed to measure the difference between systolic blood pressure(SBP)and diastolic blood pressure(DBP)as one pre-and post-test comparison of baseline and 3 months data in control and intervention groups.Results:There were no significant differences between SBP and DBP pre-and post-test in control group(P>0.050).Meanwhile,there were significant differences in reducing SBP(M=126.67;SD=18.07;95%CI=120-147.5 mmHg)and DBP(M=80.67;SD=6.91;95%CI=80-90 mmHg)pre-and post-test combination of PMR and SEs in intervention group(P<0.001).After 3-months of follow-up data,number type SBP and DBP still remained at the same levels of baseline and 3-month data in control group.While,there was an increased number of normal and prehypertension for SBP and DBP(10%vs.10%and 20%vs.31.6%)and reduced of hypertension stage I for SBP and DBP(30%vs.41.6%).Conclusions:This pilot study demonstrated effectively to reduce SBP and DBP among farmers using the combination of PMR and SEs in the agricultural health setting.
文摘OBJECTIVE To identify risk factors for relapse and death in patients with T1 to T2 breast cancer with 0-3 positive axillary lymph nodes.METHODS The case files of 540 breast cancer patients with T1-T2 tumors with 0-3 positive nodes were reviewed retrospectively. Ten-year locoregional recurrence （LRR）, distant recurrence （DR）, disease-free survival （DFS） and overall survival （OS） of the patients were analyzed. Univariate statistical analysis and Cox proportional hazards models were carried out with SPSS so ware v.16.0.RESULTS The median follow-up of all the patients was 7.2 years. On multivariate analysis, 〉 20% positive axillary nodes was the only variable that influenced LRR adversely （hazard ratio[HR], 12.816; 95% confidence interval, 4.657-35.266, P 〈 0.001）; 〉 20% positive axillary nodes and ductal carcinoma were variables that influenced DR adversely （HR, 11.088, 95% confidence interval, 3.807-32.297, P 〈 0.001; HR, 0.390, 95% confidence interval, 0.179-0.851, P = 0.018）; 1-3 positive axillary nodes and 〉 20% positive axillary nodes were the only variables that had negative e. ect on 10-year OS （HR, 2.110, 95% confi dence interval, 1.364-3.264, P = 0.001; HR, 10.244, 95% confidence interval, 3.497-30.011, P 〈 0.001） and they were also adverse prognostic variables on 10-year DFS （HR, 1.634, 95% confidence interval, 1.171-2.279, P = 0.004; HR, 7.339, 95% confi dence interval,2.906-18.530, P 〈 0.001）.CONCLUSION Axillary lymph nodal status is the only risk factor with a signifi cant impact on 10-year LRR, DR, OS and DFS.Patients with T1-T2 breast cancer with 0-3 positive lymph nodes have the LRR and DR of over 10 years, and the OS and DFS of less than 10 years, compared to patients with negative lymph nodes.Histology in primary tumors is a signifi cant prognostic factor for the 10-year DR.
文摘Background: Assessment of healthcare students’ mental health problems is an important aspect of health promotion. This study examined the roles of moral intelligence (MI) and identity styles in prediction of mental health problems in healthcare students. Methods: In a correlation study, two hundred healthcare students (100 girls, 100 boys) of Medicine, Density, and Paramedicine Colleges of Bobol University of Medical Sciences were selected. The subjects filled out three questionnaires;General Health Questionnaire (GHQ-28), Moral Competency Inventory (MCI), and Identity Style Inventory (ISI), and General Health Questionnaire (GHQ-28). Pearson correlation, multivariate analysis variance model (MANOVA), and multivariate regression used to analyze the data. Results: Boys and girls did not have a meaningful difference in the mean of total GHQ, MCI, normative and informational identity. Girls had significantly higher mean level of diffused-avoidant identity than boys. There was a positive and significant relationship between moral intelligence, normative identity and mental health problems of students. Also, there was a negative relationship (p < 0.05) between diffused-avoidant identity and mental health problems of students. Moral intelligence, informational and normative identity predicted 25.8% of the variance in mental health problems for girls’ students. Normative and diffused-avoidant identity predicted 21.6% of the variance in mental health problems for girls’ students. Conclusions: This study demonstrated that moral intelligence and identity status contributed to the mental health problems of healthcare students. University administrators should adopt strategies that strengthen the moral intelligence and identity maturity associated with university students’ mental health.
文摘<strong>Background:</strong> Ictal psychosis without remarkable cognitive impairment is uncommon occurrence, presents diagnostic challenges to clinicians, often misdiagnosed as functional psychosis. <strong>Case Presentation:</strong> We present 3 cases of young adult men admitted to psychiatric ward as functional psychosis. They presented with irritability, physical aggression and mild cognitive impairment with intense emotional symptoms, and persecutory ideas and delusions. Two were wrongly diagnose as mania while the third was mimicking schizophrenia in its presentation. They received antipsychotic treatment and misdiagnosed as functional psychosis. They did not respond well to such treatment, until, series electroencephalograms were taken which revealed evidence of ictal psychosis. All, thence, responded well to addition of antiepileptic treatment. This, not only, proves to be effective, but also determined future management and prognosis. <strong>Conclusion: </strong>These cases shine light onto the role of the frontal cortex in the genesis of quasi-manic episodes and highlight the importance of EEG investigations in first episode of acute psychosis.
基金The study protocol was approved by the Ethics Committee of Hebei General University and complied strictly with ethical requirements.Ethics Review No.2020 scientific ethics No.30.
文摘BACKGROUND The coronavirus disease 2019(COVID-19)epidemic disrupted education systems by forcing systems to shift to emergency online leaning.Online learning satisfaction affects academic achievement.Many factors affect online learning satisfaction.However there is little study focused on personal characteristics,mental status,and coping style when college students participated in emergency online courses.regression analyses were performed to identify factors that affected online learning satisfaction.RESULTS Descriptive findings indicated that 62.9%(994/1580)of students were satisfied with online learning.Factors that had significant positive effects on online learning satisfaction were online learning at scheduled times,strong exercise intensity,good health,regular schedule,focusing on the epidemic less than one hour a day,and maintaining emotional stability.Positive coping styles were protective factors of online learning satisfaction.Risk factors for poor satisfaction were depression,neurasthenia,and negative coping style.CONCLUSION College students with different personal characteristics,mental status,and coping style exhibited different degrees of online learning satisfaction.Our findings provide reference for educators,psychologists,and school adminis-trators to conduct health education intervention of college students during emergency online learning.
文摘The most stigmatized among all diseases are mental illness such as schizophrenia, both for the children themselves and for their families. The present study aims in the recording of the problems and needs of children with schizophrenia at school and identification of actions that contribute to addressing their problems; The material of study consists of recent articles concerning the subject that were found mainly in the Medline electronic database, the HEAL-Link （Hellenic Academic Libraries Link） and in the Google Scholar search engine; The school community, due to the weakness of understanding the thoughts and behavior of schizophrenic children, in conjunction with the stress of thought of this mental illness, are shaping the development of social stigma. The co-operation of mental health educators and school organizations in general is required in order to improve attitudes towards these children and students should be aware of an open world, without prejudice. The alienation of children with schizophrenia from the school community becomes a barrier to contact and collaboration with their peers. With proper education about mentally ill children teachers can remove the stigma from them.
文摘Introduction: The essential problems in providing quality and safety services to patients, rapid changes in health care settings as well as information technology require educational revision. Competency-based curriculum focuses on set of skills that students should achieve. This study reviewed characteristics of competency-based curriculum in psychiatric nursing. Methods: A literature review about a competency-based curriculum in psychiatric mental health nursing was carried out by searching databases including Iran Medex, Iran Doc, and Pub Med with key words such as competency-based education, competency-based curriculum, and competency-based curriculum in psychiatric mental health nursing. No time limitation was considered. Results: Results revealed that over 30 literatures have been done about nursing curriculum, but just several studies were done regarding competency-based curriculum and just a few about competency-based curriculum in psychiatric mental health nursing. Conclusion: Competency-based curriculum development is one of the essential steps to facilitate teaching-learning process. The revision of curriculum may decrease theory-practice gap and pave the way for graduates to have essential competences for their roles.
文摘The Clinical Strategies Implementation scale (CSI) was originally designed to be used by external reviewers in order to measure the extent to which evidence-based strategies had been implemented in the treatment of persons with schizophrenia spectrum disorders according to Resource-group Assertive Community Treatment (RACT). The present investigation had two aims: 1) to conduct a revision of CSI and to examine the revised instrument (CSI-R) in terms of interrater reliability (Study I);2) to compare assessments of CSI-R made by experienced assessors with assessments made by students in case management (Study II) in order to determine whether the instrument has validity even when more inexperienced persons are using it. In Study I six raters, who took part in 12 to 15 cases from three outpatient community mental health teams, participated. Results indicated that internal consistency of the CSI-R was strong (alpha = 0.89) as well as correlations between individual raters’ (r between 0.80-0.98). In Study II 91 newly trained RACT praxis trainees participated. Each of them followed one case for eighteen months, i.e., the client which they had been assigned during training (n = 91). The five external auditors in the education program then independently assessed the 91 cases with the CSI-R. Results showed significant correlations between experts and trainees (rho = 0.68,
