Since the reform and opening up, the development of Chinese water conservancy engineering industry has made remarkable achievements. Under this development situation, emerging water conservancy projects in various reg...Since the reform and opening up, the development of Chinese water conservancy engineering industry has made remarkable achievements. Under this development situation, emerging water conservancy projects in various regions have emerged, which has brought many opportunities for the development of Chinese water conservancy engineering. In agricultural production, small reservoir water conservancy projects have played an important role in regulating water resources, improved irrigation quality and achieved great economic and social benefits. Therefore, it plays a very important role in improving the quality of agricultural production. However, in the process of reservoir construction, there are still some problems, which can not effectively ensure the engineering economy. Therefore, it is necessary to take scientific and reasonable measures to strengthen the construction management of reservoir engineering, so as to promote the sustainable development of water conservancy engineering.展开更多
With the continuous advancement of China’s infrastructure construction to the west,according to the geographic situation in the southwest region,such as mountainous areas and complex terrain,the road construction pro...With the continuous advancement of China’s infrastructure construction to the west,according to the geographic situation in the southwest region,such as mountainous areas and complex terrain,the road construction process is inevitably accompanied by earth and rock blasting.To improve the quality and safety of the project,this paper addresses the problems of land and rock blasting faced in the construction of mountain road projects,taking the research of rock dynamic mechanics test as the starting point,and using a combination of theoretical analysis and experimental research methods.The specific research content includes the following parts:dynamic impact compression test(SHPB),dynamic splitting tensile test,and stress-strain curve analysis of the test results,which provides the theoretical basis and numerical parameters for the numerical simulation of future engineering blasting.展开更多
Betula platyphylla and Betula costata are important species in mixed broadleaved-Korean pine(Pinus koraiensis)forests.However,the specific ways in which their growth is affected by warm temperatures and drought remain...Betula platyphylla and Betula costata are important species in mixed broadleaved-Korean pine(Pinus koraiensis)forests.However,the specific ways in which their growth is affected by warm temperatures and drought remain unclear.To address this issue,60 and 62 tree-ring cores of B.platyphylla and B.costata were collected in Yichun,China.Using dendrochronological methods,the response and adaptation of these species to climate change were examined.A“hysteresis effect”was found in the rings of both species,linked to May–September moisture conditions of the previous year.Radial growth of B.costata was positively correlated with the standardized precipitation-evapotranspiration index(SPEI),the precipitation from September to October of the previous year,and the relative humidity in October of the previous year.Growth of B.costata is primarily restricted by moisture conditions from September to October.In contrast,B.platyphylla growth is mainly limited by minimum temperatures in May–June of both the previous and current years.After droughts,B.platyphylla had a faster recovery rate compared to B.costata.In the context of rising temperatures since 1980,the correlation between B.platyphylla growth and monthly SPEI became positive and strengthened over time,while the growth of B.costata showed no conspicuous change.Our findings suggest that the growth of B.platyphylla is already affected by warming temperatures,whereas B.costata may become limited if warming continues or intensifies.Climate change could disrupt the succession of these species,possibly accelerating the succession of pioneer species.The results of this research are of great significance for understanding how the growth changes of birch species under warming and drying conditions,and contribute to understanding the structural adaptation of mixed broadleaved-Korean pine(Pinus koraiensis)forests under climate change.展开更多
The leukaemia cells HL60, incubated in 10 mM/ml ALA (5-aminolevulinic) for 4 hours, were carried an experimental research with fluorescent probes in photodynamic therapy (PDT) based on ALA by using PDT reaction room (...The leukaemia cells HL60, incubated in 10 mM/ml ALA (5-aminolevulinic) for 4 hours, were carried an experimental research with fluorescent probes in photodynamic therapy (PDT) based on ALA by using PDT reaction room (The average fluence rate of the 412 nm source was 5 mW/cm2). Cells viability were determined using a Cell Counting Kit-8 (CCK-8) assay, and PpIX Photobleaching of subcellular distributed sites of HL60 cells in vitro were investigated by fluorescence spectra acquired during treatment. The results showed that the fluorescence intensity of mitochondria, lysosomes, endoplasmic reticulum had decreased by 81.5%, 52.3% and 21.0%, respectively, compared with their initial values after a 45-minute light treatment. The rate of PpIX photobleaching in mitochondria was significantly higher than others. Addi-tionally, the change of the activity of HL60 cells was basically characterized by the change fluorescence intensity in mitochondria, which suggest that mitochondria is one of main therapeutic targets of photodynamic therapy.展开更多
文摘Since the reform and opening up, the development of Chinese water conservancy engineering industry has made remarkable achievements. Under this development situation, emerging water conservancy projects in various regions have emerged, which has brought many opportunities for the development of Chinese water conservancy engineering. In agricultural production, small reservoir water conservancy projects have played an important role in regulating water resources, improved irrigation quality and achieved great economic and social benefits. Therefore, it plays a very important role in improving the quality of agricultural production. However, in the process of reservoir construction, there are still some problems, which can not effectively ensure the engineering economy. Therefore, it is necessary to take scientific and reasonable measures to strengthen the construction management of reservoir engineering, so as to promote the sustainable development of water conservancy engineering.
文摘With the continuous advancement of China’s infrastructure construction to the west,according to the geographic situation in the southwest region,such as mountainous areas and complex terrain,the road construction process is inevitably accompanied by earth and rock blasting.To improve the quality and safety of the project,this paper addresses the problems of land and rock blasting faced in the construction of mountain road projects,taking the research of rock dynamic mechanics test as the starting point,and using a combination of theoretical analysis and experimental research methods.The specific research content includes the following parts:dynamic impact compression test(SHPB),dynamic splitting tensile test,and stress-strain curve analysis of the test results,which provides the theoretical basis and numerical parameters for the numerical simulation of future engineering blasting.
基金the Key Project of the China National Key Research and Development Program(2021YFD2200401)the National Natural Science Foundation of China(42177421 and 41877426)。
文摘Betula platyphylla and Betula costata are important species in mixed broadleaved-Korean pine(Pinus koraiensis)forests.However,the specific ways in which their growth is affected by warm temperatures and drought remain unclear.To address this issue,60 and 62 tree-ring cores of B.platyphylla and B.costata were collected in Yichun,China.Using dendrochronological methods,the response and adaptation of these species to climate change were examined.A“hysteresis effect”was found in the rings of both species,linked to May–September moisture conditions of the previous year.Radial growth of B.costata was positively correlated with the standardized precipitation-evapotranspiration index(SPEI),the precipitation from September to October of the previous year,and the relative humidity in October of the previous year.Growth of B.costata is primarily restricted by moisture conditions from September to October.In contrast,B.platyphylla growth is mainly limited by minimum temperatures in May–June of both the previous and current years.After droughts,B.platyphylla had a faster recovery rate compared to B.costata.In the context of rising temperatures since 1980,the correlation between B.platyphylla growth and monthly SPEI became positive and strengthened over time,while the growth of B.costata showed no conspicuous change.Our findings suggest that the growth of B.platyphylla is already affected by warming temperatures,whereas B.costata may become limited if warming continues or intensifies.Climate change could disrupt the succession of these species,possibly accelerating the succession of pioneer species.The results of this research are of great significance for understanding how the growth changes of birch species under warming and drying conditions,and contribute to understanding the structural adaptation of mixed broadleaved-Korean pine(Pinus koraiensis)forests under climate change.
文摘The leukaemia cells HL60, incubated in 10 mM/ml ALA (5-aminolevulinic) for 4 hours, were carried an experimental research with fluorescent probes in photodynamic therapy (PDT) based on ALA by using PDT reaction room (The average fluence rate of the 412 nm source was 5 mW/cm2). Cells viability were determined using a Cell Counting Kit-8 (CCK-8) assay, and PpIX Photobleaching of subcellular distributed sites of HL60 cells in vitro were investigated by fluorescence spectra acquired during treatment. The results showed that the fluorescence intensity of mitochondria, lysosomes, endoplasmic reticulum had decreased by 81.5%, 52.3% and 21.0%, respectively, compared with their initial values after a 45-minute light treatment. The rate of PpIX photobleaching in mitochondria was significantly higher than others. Addi-tionally, the change of the activity of HL60 cells was basically characterized by the change fluorescence intensity in mitochondria, which suggest that mitochondria is one of main therapeutic targets of photodynamic therapy.
