To ensure the efficient use of resources,particularly in water-scarce arid and semi-arid regions where abiotic stress threatens food security,assessing soil and climate suitability for specific crops is crucial.Simult...To ensure the efficient use of resources,particularly in water-scarce arid and semi-arid regions where abiotic stress threatens food security,assessing soil and climate suitability for specific crops is crucial.Simultaneously,food production must align with sustainable development goals by minimizing negative environmental impacts.Therefore,establishing agro-climatic suitability using a spatiotemporal approach is essential.This involves three key steps:first,determining the climatically appropriate months based on the species’requirements(temporal suitability),and second,establishing the soil suitability of specific plots(spatial suitability).Following this,quantifying crop evapotranspiration allows for optimized water use.This study used climatic and soil variables from diverse data sources to characterize the study area.Subsequently,suitability classes for Portulaca oleracea were determined based on existing literature.Our analysis concerning temporal suitability revealed that June and July are the optimal months for sowing this species in all of the municipalities.Spatially,approximately 30%of the agricultural land use of the study area exhibits a highly suitable class in most municipalities.Both dimensions,the temporal and the spatially,were validated through Chi square(χ^(2))Goodness-of-Fit test and theχ^(2)test of independence,respectively.Consequently,for a one-month production cycle during periods of high suitability,estimated evapotranspiration values are between 210 and 245 mm.In brief,the study area demonstrates favorable agro-climatic conditions for P.oleracea cultivation in specific months of the year according to parameters used,with potential in a large proportion of agricultural land and achievable water requirements.展开更多
Forest ecosystems worldwide can be affected by extreme climatic events.Trees respond to these occurrences in multidimensional ways,involving various mechanisms,to deal with the effects and restore the forests to their...Forest ecosystems worldwide can be affected by extreme climatic events.Trees respond to these occurrences in multidimensional ways,involving various mechanisms,to deal with the effects and restore the forests to their optimal state.Such abilities are known as resilience.Tree ring analysis can be used to evaluate drought resilience.Analysis of dendrophenotypes,together with genetic studies,has become an essential tool for identifying drought resilient genotypes.This study aimed to determine the dendrogenomic resilience mechanisms in the fragmented,isolated,rare endemic Mexican species Picea martinezii and P.mexicana by analysis of annual rings and the associations with SNP markers identified by genotyping by sequencing(GBS).Increment cores and needles for GBS for resilience analysis were collected from P.martinezii trees in three populations,and from P.mexicana trees in two populations.The results show that fundamental dendrogenomic mechanisms were associated with drought resilience in P.martinezii and P.mexicana.PC1 in PCA for five outlier SNPs was linked to annual tracheid width variations in P.martinezii caused by severe drought events in 1962,1989,1998 and 2011.These five outlier SNPs were located in genes coding the proteins reticulon-like protein B22,pollen-specific leucine-rich repeat extension,ornithine decarboxylase like,LisH/CRA/RING-U-box domains-containing protein and proline transporter 2-like isoform X1,which are important in the dry stress tolerance metabolism involved in the resilience response in plants.The discovery of genetic markers associated with drought resilience highlights the importance of preserving genetic diversity.展开更多
The presence of heterozygous individuals in a population is crucial for maintaining genetic diversity,which can positively affect fitness and adaptability to environmental changes.While inbreeding generally reduces th...The presence of heterozygous individuals in a population is crucial for maintaining genetic diversity,which can positively affect fitness and adaptability to environmental changes.While inbreeding generally reduces the proportion of heterozygous individuals in a population,polyploidy tends to increase the proportion.North American Populus tremuloides is one of the most widely distributed and ecologically important tree species in the Northern Hemisphere.However,genetic variation in Mexican populations of P.tremuloides,including the genetic signatures of their adaptation to a variety of environments,remains largely uncharacterized.The aim of this study was to analyze how inbreeding coefficient(FIS)and ploidy are associated with clonal richness,population cover,climate and soil traits in 91 marginal to small,isolated populations of this tree species throughout its entire distribution in Mexico.Genetic variables were determined using 36,810 filtered SNPs derived from genome re-sequencing.We found that FIS was approximately between 0 and e1,indicating an extreme heterozygosity excess.One key contributor to the observed extreme heterozygosity excess was asexual reproduction,although ploidy levels cannot explain this excess.Analysis of all neutral SNPs showed that asexual reproduction was positively correlated with observed heterozygosity(Ho)but negatively correlated with expected heterozygosity(He).Analysis of outlier SNPs also showed that asexual reproductionwas positively correlated with Ho and negatively correlated with He,although this latter correlation was not significant.These findings support the presence of a Meselson effect.展开更多
The cultivation of Soledad pepper(Capsicum annuum L.)is essential in Oaxaca and Veracruz,but it faces issues with pests and diseases,which affect yield and cause economic losses.To mitigate these impacts,farmers have ...The cultivation of Soledad pepper(Capsicum annuum L.)is essential in Oaxaca and Veracruz,but it faces issues with pests and diseases,which affect yield and cause economic losses.To mitigate these impacts,farmers have started using biostimulants such as chitosan and plant growth promoting bacteria instead of agrochemicals due to their environmental and health benefits.This study evaluated the effect of Bacillus subtilis and chitosan,both individually and combined,on the growth,yield,and fruit quality of Soledad pepper under greenhouse conditions.Four treatments were applied at different stages of the crop cycle:Q(Chitosan),BS(Bacillus subtilis),Q+BS(Chitosan+Bacillus subtilis),and T(Control).The results showed that the combination of chitosan and Bacillus subtilis significantly improved plant growth,especially in height and stem diameter.The chitosan treatment produced the highest number of fruits and plant weight,while the combination of chitosan and Bacillus subtilis enhanced fruit quality,increasing characteristics such as size,weight,pericarp thickness,and physicochemical parameters,notably in brix degrees,citric acid percentage,and pH,outperforming the individual treatments and the control.展开更多
Recently,the Andean subparamo in Colombia has experienced severe wildfires,but little is known about the functional composition of recovering or not after a wildfire.Therefore,we examined the functional community comp...Recently,the Andean subparamo in Colombia has experienced severe wildfires,but little is known about the functional composition of recovering or not after a wildfire.Therefore,we examined the functional community composition subparamo affected byfire in 2016.We documented how functional traits changed 31 months after the disturbance and compared them with an unburned site.We sampled from one to two years after the fire every four months,then registered all recruits in 1655m plots.New individuals were classified into strategy functional groups based on the traits of persistence and dispersal.The first group was stem type and regeneration mechanism(seedling and resprout),and the second was fruit type and dispersal mode.We investigated the degree to which functional diversity changes plant communities over time(woody and non-woody),and we compared it with an unburned site.The most relevant results showed that resprouts and seed regenerated increased post-fire time and significant differences between sampling periods.The anemochory is the most relevant dispersal mode that indicates the community capacity to colonize the new gaps opened by the fire rapidly.We discuss how wildfire appears to be a triggering factor for persistence and dispersal strategy groups in subparamo burned given their characteristics of tolerance to stress.For this reason,a greater functional divergence between the ecosystems studied post-fire recovery has been related to higher levels of biodiversity at the landscape scale due to the high degree of endemism and significant differences in species composition between paramos.展开更多
In this article, we study the ability of error-correcting quantum codes to increase the fidelity of quantum states throughout a quantum computation. We analyze arbitrary quantum codes that encode all qubits involved i...In this article, we study the ability of error-correcting quantum codes to increase the fidelity of quantum states throughout a quantum computation. We analyze arbitrary quantum codes that encode all qubits involved in the computation, and we study the evolution of n-qubit fidelity from the end of one application of the correcting circuit to the end of the next application. We assume that the correcting circuit does not introduce new errors, that it does not increase the execution time (i.e. its application takes zero seconds) and that quantum errors are isotropic. We show that the quantum code increases the fidelity of the states perturbed by quantum errors but that this improvement is not enough to justify the use of quantum codes. Namely, we prove that, taking into account that the time interval between the application of the two corrections is multiplied (at least) by the number of qubits n (due to the coding), the best option is not to use quantum codes, since the fidelity of the uncoded state over a time interval n times smaller is greater than that of the state resulting from the quantum code correction.展开更多
Coastal zones are very dynamic and fragile environments, constituting a landscape ever more heterogeneous, fragmented and with increasing levels of complexity due to the changing relationship between man and nature. I...Coastal zones are very dynamic and fragile environments, constituting a landscape ever more heterogeneous, fragmented and with increasing levels of complexity due to the changing relationship between man and nature. Integrated coastal zone management therefore requires detailed knowledge of the system and its components, based—to a large extent—on technical and scientific information. However, the information generated must be in line with the political requirements necessary for decision-making and planning. Thus the use of indicators to give a simplified view of the many components of the territory, and at the same time to provide important information about patterns or trends, becomes a tool of the utmost importance. These indicators can be understood as measurable characteristics of the environment, which facilitate comprehension of the processes occurring at different scales and serve as a reference to inform the population and support decision-making. The aim of the present note is to demonstrate briefly the need to develop geographical-environmental and natural risk indicators to facilitate comprehension of the dynamic of spatial and temporal landscape patterns, particularly in coastal environments. This approach offers an historical summary of the natural, socio-economic and political processes which currently make up the territory, and which without doubt will continue to influence it in the future. At the same time, it is proposed that information should be integrated on the basis of this framework with a view to generating spatial decision support systems in a context of planning and integrated management of the coastal zones of Chile.展开更多
Purpose:This paper focuses on scientific journals’policies on open access and open science.The subject has gained increasing relevance,driven by the need for more-democratic access to knowledge and improved research ...Purpose:This paper focuses on scientific journals’policies on open access and open science.The subject has gained increasing relevance,driven by the need for more-democratic access to knowledge and improved research visibility,which require eliminating the financial,legal,and technical barriers that restrict access to scientific output.Design/methodology/approach:This paper uses the findings of FECYT’s 2023 Assessment of the Editorial and Scientific Quality of Spanish Scientific Journals,with 254 participating journals,as its case study.Open science indicators assess the transparency of policies on content access,reuse,openness,and reproducibility.Nonparametric tests analyse the relationship between the indicators and the dimensions of publisher type and subject area.Findings:High compliance rates are found for indicators related to publication licences and intellectual property rights.Only 37%of the journals examined post their editorial policy on Sherpa Romeo.Ninety-four percent publish open access.However,open peer review is rarely applied(0.38%of the journals).Journals in Communication,Information and Scientific Documentation,Fine Arts,Education Science,and Biomedical Sciences have high compliance percentages.Most journals(83%)are institutional,with universities and associations generally exhibiting better results.Research limitations:This study is based on specific indicators that do not cover all the factors that influence the transition toward open science;for example,editorial culture and technological infrastructure are not envisaged.Furthermore,differences in open science implementation are identified between disciplinary areas and between publisher types,but the underlying causes of these differences are not thoroughly investigated.Future research could address these points for a fuller understanding.Practical implications:This study highlights the need for journals to improve transparency by adopting open peer review and clear policies.These changes enhance accessibility and credibility,fostering inclusive knowledge dissemination.Institutions and policymakers should support these efforts to boost research impact.Originality/value:This study offers insights into open science practices in Spanish journals,a growing academic topic.Its originality lies in examining open science indicators across disciplines and publishers.By identifying strengths and gaps,the study helps journals enhance transparency.展开更多
Obesity and type 2 diabetes mellitus(T2DM)are chronic pathologies with a high incidence worldwide.They share some pathological mechanisms,including hyperinsulinemia,the production and release of hormones,and hyperglyc...Obesity and type 2 diabetes mellitus(T2DM)are chronic pathologies with a high incidence worldwide.They share some pathological mechanisms,including hyperinsulinemia,the production and release of hormones,and hyperglycemia.The above,over time,affects other systems of the human body by causing tissue hypoxia,low-grade inflammation,and oxidative stress,which lay the pathophysiological groundwork for cancer.The leading causes of death globally are T2DM and cancer.Other main alterations of this pathological triad include the accumulation of advanced glycation end products and the release of endogenous alarmins due to cell death(i.e.,damage-associated molecular patterns)such as the intracellular proteins high-mobility group box protein 1 and protein S100 that bind to the receptor for advanced glycation products(RAGE)-a multiligand receptor involved in inflammatory and metabolic and neoplastic processes.This review analyzes the latest advanced reports on the role of RAGE in the development of obesity,T2DM,and cancer,with an aim to understand the intracellular signaling mechanisms linked with cancer initiation.This review also explores inflammation,oxidative stress,hypoxia,cellular senescence,RAGE ligands,tumor microenvironment changes,and the“cancer hallmarks”of the leading tumors associated with T2DM.The assimilation of this information could aid in the development of diagnostic and therapeutic approaches to lower the morbidity and mortality associated with these diseases.展开更多
The“oil stain disease”has become a phytosanitary status that involves economic losses for farmers who produce gulupa(Passiflora edulis Sims).For this reason,this research aimed to evaluate the biocontrol activity of...The“oil stain disease”has become a phytosanitary status that involves economic losses for farmers who produce gulupa(Passiflora edulis Sims).For this reason,this research aimed to evaluate the biocontrol activity of Bacillus subtilis ATCC 55033 in a culture medium based on fermented millet as a biocontrol product of the disease.Initially,metabolite production of seven strains of B.subtilis and a reference strain B.s(ATCC 55033)was evaluated;in addition,the in vitro antagonistic ability was evaluated against Xanthomonas axonopodis.Two experiments were performed under in vitro conditions:(1)study of the presence of halos of hemolysis due to metabolite production;(2)analysis of the antagonistic ability by using double layer.It was observed that concerning the average,a number five times bigger of halos of hemolysis and 10 times bigger halos of inhibition in vitro on the growth of X.axonopodis in the strains B.s(ATCC 55033)and B.s TB2 over other strains.Subsequently,the evaluation was performed under greenhouse conditions,based on a randomized block design,in which two treatments were applied over the soil:(1)application of the fermented medium based on millet with B.s ATCC 55033,24 h before X.a inoculation;(2)application of 5 d post-inoculation.It was observed that the treatment,previous infective process,obtained an average percentage of severity equal to 42.044%.In addition,after the evaluation month,a foliage restoration was presented.In conclusion,it is suggested that these products could act as inducers in the plant systemic resistance to trigger defense responses to infection of X.a.展开更多
The use of unmanned aerial vehicles(UAV)for forest monitoring has grown significantly in recent years,providing information with high spatial resolution and temporal versatility.UAV with multispectral sensors allow th...The use of unmanned aerial vehicles(UAV)for forest monitoring has grown significantly in recent years,providing information with high spatial resolution and temporal versatility.UAV with multispectral sensors allow the use of indexes such as the normalized difference vegetation index(NDVI),which determines the vigor,physiological stress and photo synthetic activity of vegetation.This study aimed to analyze the spectral responses and variations of NDVI in tree crowns,as well as their correlation with climatic factors over the course of one year.The study area encompassed a 1.6-ha site in Durango,Mexico,where Pinus cembroides,Pinus engelmannii,and Quercus grisea coexist.Multispectral images were acquired with UAV and information on meteorological variables was obtained from NASA/POWER database.An ANOVA explored possible differences in NDVI among the three species.Pearson correlation was performed to identify the linear relationship between NDVI and meteorological variables.Significant differences in NDVI values were found at the genus level(Pinus and Quercus),possibly related to the physiological features of the species and their phenology.Quercus grisea had the lowest NDVI values throughout the year which may be attributed to its sensitivity to relative humidity and temperatures.Although the use of UAV with a multispectral sensor for NDVI monitoring allowed genera differentiation,in more complex forest analyses hyperspectral and LiDAR sensors should be integrated,as well other vegetation indexes be considered.展开更多
Interspecific interactions are key drivers of individual and population-level fitness in a wide range of animals.However,in marine ecosystems,it is relatively unknown which biotic and abiotic factors impact behavioral...Interspecific interactions are key drivers of individual and population-level fitness in a wide range of animals.However,in marine ecosystems,it is relatively unknown which biotic and abiotic factors impact behavioral interactions between competing species.We assessed the impact of weather,marine productivity,and population structure on the behavioral agonistic interactions between South American fur seals(SAFSs),Arctocephalus australis,and South American sea lions(SASLs),Otaria byronia,in a breeding colony of SAFS.We hypothesized that agonistic interactions between SAFSs and SASLs respond to biotic and abiotic factors such as SAFS population structure,marine productivity,and weather.We found that SASL and SAFS interactions almost always resulted in negative impacts on the social structure or reproductive success of the SAFS colony.SASL adult males initiated stampedes of SAFS and/or abducted and predated SAFS pups.Adult SAFS males abundance and severe weather events were negatively correlated with agonistic interactions between species.However,proxies for lower marine productivity such as higher sea surface temperature and lower catches of demerso-pelagic fish were the most important predictors of more frequent agonistic interactions between SAFS and SASL.Under the current scenario of decline in marine biomass due to global climate change and overfishing,agonistic interactions between competing marine predators could increase and exacerbate the negative impacts of environmental change in these species.展开更多
Tropical mountain ranges shape the structure of tree communities and promote highly diverse natural habitats.The“Bosque Protector Chong on-Colonche”(BPCC),an 86,000-ha mountain formation situated on the coast of Ecu...Tropical mountain ranges shape the structure of tree communities and promote highly diverse natural habitats.The“Bosque Protector Chong on-Colonche”(BPCC),an 86,000-ha mountain formation situated on the coast of Ecuador,is biogeographically important for the region by connecting floristic elements of the wet Choco and the dry Tumbesian forests.Our understanding of the factors that model tree and palm diversity and distribution in this mountain range are limited.We measured and identified all trees and palms(DBH≥10 cm)in 289 plots of0.2 ha,distributed throughout BPCC.We used generalized linear models to explain the relationship between forest diversity and structure and climatic variables(temperature,rain,aridity),and altitude.We then used cluster and non-metric multidimensional scale(NMDS)analyses to search for distinct forest communities within the BPCC.Variance partition(varpart)was used to determine which predictor variables best explained these distinct forest communities.A species indicator analysis identified the species most likely to define these distinct forest communities.Finally,we carried out a niche modeling approach to identify the potential distribution of these forest communities within BPCC.In total,we identified 220 tree and palm species in our survey.The average number of species per plot was 17.8±5.8,ranging from 3 to 40 species.Classification methods sorted the 289study plots into six different forest communities,three communities in the dry forest and three in the semi-humid Garúa forest.Precipitation and temperature,but not altitude or aridity,explained floristic composition.These results emphasize the high but little cataloged diversity in the lowland mountain rainforests of coastal Ecuador.展开更多
A highly acidic spill from one of the most important copper mines in the Americas (Buenavista del Cobre) occurred in Sonora, Mexico in August, 2014. 40,000 m3 of metals-enriched sulphate solution escaped into the Sono...A highly acidic spill from one of the most important copper mines in the Americas (Buenavista del Cobre) occurred in Sonora, Mexico in August, 2014. 40,000 m3 of metals-enriched sulphate solution escaped into the Sonora River representing the worst ecological disaster in Mexican history. The spill affected the economy, water accessibility and the health of residents near the river. Despite the economic importance of mining in this area, no environmental assessment was undertaken. There is no information about the health impact of this event on the local population. The study assesses the health risk among children exposed to arsenic and mercury via groundwater in five communities located in a mining area into the Sonora River Basin, Mexico. Local drinking water from the localities was sampled one year after the spill and it was analyzed for arsenic and mercury by Atomic Absorption Spectrometry coupled with Hydride Generation (AAS/HG). Further, some of the traditional local foods were sampled and analyzed for the same elements. Results indicate that levels of arsenic in drinking water did not exceed the Mexican Norm (25 μg As/L) or the EPA Guideline (10 μg As/L). The concentrations of mercury exceeded the WHO and Mexican Legislation value (1.0 μg Hg/L). The Hazard Quotient (HQ) values for arsenic were >1 in 42% of children exposed and for mercury in 67% of the children. Foods concentrations contained in the ranges of 9.2 to 62.0 μg As/Kg and 0.28 to 42 μg Hg/Kg for arsenic and mercury respectively. These values are below the Codex Alimentarius limits. Children affected by mining activities are at risk of developing chronic diseases associated with low arsenic and mercury exposure via groundwater consumption, without consideration of the contribution from these metals by other important exposures routes.展开更多
Objective. The host immune response is essential for restraining both HPV infections and HPV- related cervical cancer. We previously reported a direct correlation between proteolytic activity and malignant progression...Objective. The host immune response is essential for restraining both HPV infections and HPV- related cervical cancer. We previously reported a direct correlation between proteolytic activity and malignant progression from precursor lesions to invasive cervical carcinoma. The present study was undertaken to investigate whether proteinases from cervical carcinoma extracts and representative purified proteinases involved in tumor progression could regulate lymphocyte proliferation to phytohemagglutinin (PHA) mitogen. Methods. Extracts were prepared from tissue samples obtained from patients with invasive cervical squamous carcinoma, squamous intra- epithelial lesions or women with normal cervix. Lymphocytes obtained from a single healthy donor were pre- incubated with one of these extracts in the presence or absence of proteinase inhibitors, and stimulated with PHA during 72 h. The proliferative response was measured using the 3- (4,5- dimethyl- thiazol- 2- yl)- 2,5- diphenyl- tetrazolium bromide (MTT) method (re- validated with thymidine uptake). Results. Lymphocyte proliferation was significantly decreased by cervical carcinoma extracts, while only slightly decreased by squamous intra- ep- ithelial lesions or normal extracts. Inhibitor assays indicated that proteinases from cervical carcinoma were responsible for 53.30% of total suppressive activity. We found that purified enzymes such as trypsin, cathepsin B, uPA and type IV collagenase suppressed the proliferative response in a dose- dependent fashion. Conclusions. Our data suggest that in addition to the classic role in tumor invasion, proteases could represent an immune evasion mechanism in cervical carcinoma.展开更多
This paper presents and evaluates two novel ordinal classification methods for wind speed prediction,considering three prediction time-horizons:1h,4h,and 8h.To address the problem,wind speed values are discretised int...This paper presents and evaluates two novel ordinal classification methods for wind speed prediction,considering three prediction time-horizons:1h,4h,and 8h.To address the problem,wind speed values are discretised into four classes,critical for wind farm management.Each class represents essential information for wind farm production,ranging from very low wind speeds to extreme wind speed events and the corresponding production conditions,facilitating operational decisions for wind farm operators.Ordinal classifiers are more suitable than nominal methods to tackle this problem.The study’s primary objective is to compare recently proposed ordinal classifiers for addressing the challenges of wind speed prediction with a focus on extreme wind conditions,which are responsible for many turbine shutdowns.Hourly wind speed measurements from a Spanish wind farm and predictor variables from the European Centre for Medium-Range Weather Forecasts Reanalysis v5(ERA5 Reanalysis)model are used.The proposed methods include an Artificial Neural Network(ANN)model implementing the Cumulative Link Model as an ordinal output function(MLP-CLM^(O)),which emphasises overall performance,and an ANN model optimised using a soft labelling technique based on triangular distributions(MLP-T^(O)),which excels at handling extreme class performance.The results demonstrate the superiority of both approaches over other nominal and ordinal methods across performance metrics that account for the unbalanced nature and ordinality of the data.MLP-CLMO excels in overall and ordinal performance,while MLP-TO demonstrates superior handling of the extreme class predictions.展开更多
Computer vision is increasingly used in farmers'fields and agricultural experiments to quantify important traits.Imaging setups with a sub-millimeter ground sampling distance enable the detection and tracking of p...Computer vision is increasingly used in farmers'fields and agricultural experiments to quantify important traits.Imaging setups with a sub-millimeter ground sampling distance enable the detection and tracking of plant features,including size,shape,and colour.Although today's AI-driven foundation models segment almost any object in an image,they still fail for complex plant canopies.To improve model performance,the global wheat dataset consortium assembled a diverse set of images from experiments around the globe.After the head detection dataset(GWHD),the new dataset targets a full semantic segmentation(GWFSS)of organs(leaves,stems and spikes)covering all developmental stages.Images were collected by 11 institutions using a wide range of imaging setups.Two datasets are provided:ⅰ)a set of 1096 diverse images in which all organs were labelled at the pixel level,and(ⅱ)a dataset of 52,078 images without annotations available for additional training.The labelled set was used to train segmentation models based on DeepLabV3Plus and Segformer.Our Segformer model performed slightly better than DeepLabV3Plus with a mIOU for leaves and spikes of ca.90%.However,the precision for stems with 54%was rather lower.The major advantages over published models are:ⅰ)the exclusion of weeds from the wheat canopy,ⅱ)the detection of all wheat features including necrotic and se-nescent tissues and its separation from crop residues.This facilitates further development in classifying healthy vs.unhealthy tissue to address the increasing need for accurate quantification of senescence and diseases in wheat canopies.展开更多
Chronic wounds are defined as wounds that fail to proceed through the normal phases of wound healing in an orderly and timely manner.The most common and inevitable impairment to wound healing is the installation of an...Chronic wounds are defined as wounds that fail to proceed through the normal phases of wound healing in an orderly and timely manner.The most common and inevitable impairment to wound healing is the installation of an infection,usually in the case of chronic wounds.Therefore,the objective of the present review was to identify the importance of copper nanoparticles in dressings for wound healing.Nanoparticles such as silver,gold and copper combat infectious processes through the inhibition of protein synthesis,peroxidation of the cell membrane and destroying the nucleic acids of bacteria and viruses.Among bioactive nanoparticles,copper plays a complex role in various cells,it modulates several cytokines and growth factor mechanisms of action and is essentially involved in all stages of the wound healing process.More importantly,copper plays a key role in skin regeneration and angiogenesis and accelerates the healing process through induction of vascular endothelial growth factor(VEGF)and angiogenesis by hypoxia-induced factor-1-alpha(HIF-1α)action where copper enhances HIF-1αexpression and HIF-1αbinding to the critical motifs in the promoter and putative enhancer regions of HIF-1-regulated genes.展开更多
Bats play crucial ecosystem services as seed dispersers,pollinators,controllers of insects,and nutrient recyclers.However,there has not been a thorough global review evaluating these roles in bats across all biogeogra...Bats play crucial ecosystem services as seed dispersers,pollinators,controllers of insects,and nutrient recyclers.However,there has not been a thorough global review evaluating these roles in bats across all biogeographical regions of the world.We reviewed the literature published during the last two decades and identified 283 relevant studies:78 dealt with the control of potential insect pests by bats,80 related to the suppression of other arthropods,60 on the dispersal of native or endemic seeds,11 dealt with the dispersal of seeds of introduced plants,29 on the pollination of native or endemic plants,1 study on pollination of introduced plants,and 24 on the use of guano as fertilizer.Our literature search showed that queries combining the terms“seed dispersal,”“insectivorous bats,”“nectarivorous bats,”“use of guano,”and“ecosystem services”returned 577 studies,but half were experimental in nature.We found that the evaluation of ecosystem services by bats has been mostly conducted in the Neotropical and Palearctic regions.To detect differences across relevant studies,and to explain trends in the study of ecosystem services provided by bats,we performed generalized linear mixed models(GLMM)fitted with a Poisson distribution to analyze potential differences among sampling methods.We identified 409 bat species that provide ecosystem services,752 insect species consumed by bats and 549 plant species either dispersed or pollinated by bats.Our review summarizes the importance of conserving bat populations and the ecological services they provide,which is especially important during the current pandemic.展开更多
文摘To ensure the efficient use of resources,particularly in water-scarce arid and semi-arid regions where abiotic stress threatens food security,assessing soil and climate suitability for specific crops is crucial.Simultaneously,food production must align with sustainable development goals by minimizing negative environmental impacts.Therefore,establishing agro-climatic suitability using a spatiotemporal approach is essential.This involves three key steps:first,determining the climatically appropriate months based on the species’requirements(temporal suitability),and second,establishing the soil suitability of specific plots(spatial suitability).Following this,quantifying crop evapotranspiration allows for optimized water use.This study used climatic and soil variables from diverse data sources to characterize the study area.Subsequently,suitability classes for Portulaca oleracea were determined based on existing literature.Our analysis concerning temporal suitability revealed that June and July are the optimal months for sowing this species in all of the municipalities.Spatially,approximately 30%of the agricultural land use of the study area exhibits a highly suitable class in most municipalities.Both dimensions,the temporal and the spatially,were validated through Chi square(χ^(2))Goodness-of-Fit test and theχ^(2)test of independence,respectively.Consequently,for a one-month production cycle during periods of high suitability,estimated evapotranspiration values are between 210 and 245 mm.In brief,the study area demonstrates favorable agro-climatic conditions for P.oleracea cultivation in specific months of the year according to parameters used,with potential in a large proportion of agricultural land and achievable water requirements.
基金funding from the Mixed Fund of the National Council of Humanities,Sciences,and Technologies of Mexico and the National Forestry Commission(CONACYT-CONAFOR-2017-4-292615),awarded to Christian WehenkelSECIHTI provided a graduate scholarship to Carlos Alberto Segura Sanchez(776540).
文摘Forest ecosystems worldwide can be affected by extreme climatic events.Trees respond to these occurrences in multidimensional ways,involving various mechanisms,to deal with the effects and restore the forests to their optimal state.Such abilities are known as resilience.Tree ring analysis can be used to evaluate drought resilience.Analysis of dendrophenotypes,together with genetic studies,has become an essential tool for identifying drought resilient genotypes.This study aimed to determine the dendrogenomic resilience mechanisms in the fragmented,isolated,rare endemic Mexican species Picea martinezii and P.mexicana by analysis of annual rings and the associations with SNP markers identified by genotyping by sequencing(GBS).Increment cores and needles for GBS for resilience analysis were collected from P.martinezii trees in three populations,and from P.mexicana trees in two populations.The results show that fundamental dendrogenomic mechanisms were associated with drought resilience in P.martinezii and P.mexicana.PC1 in PCA for five outlier SNPs was linked to annual tracheid width variations in P.martinezii caused by severe drought events in 1962,1989,1998 and 2011.These five outlier SNPs were located in genes coding the proteins reticulon-like protein B22,pollen-specific leucine-rich repeat extension,ornithine decarboxylase like,LisH/CRA/RING-U-box domains-containing protein and proline transporter 2-like isoform X1,which are important in the dry stress tolerance metabolism involved in the resilience response in plants.The discovery of genetic markers associated with drought resilience highlights the importance of preserving genetic diversity.
基金We thank the Mexican Consejo Nacional de Humanidades,Ciencias y Tecnologías(CONAHCYT)for the financial support provided to the first author to carry out his training in the Institutional Doctoral Program in Agricultural and Forestry Sciences(PIDCAFUJED)with Scholarship No.334852financial support with agreement number CONACYT-FRQ-2016:279459 for the project“Genome-wide scans for detecting adaptation to climate and soil in Populus tremuloides as the most widely distributed tree species in North America”Dr.Jesús M.Olivas-García assisted in the sampling in the state of Chihuahua,Mexico,and Katrin Groppe,Thünen Institute of Forest Genetics,Germany,provided excellent lab work.The Emerging Leaders of the Americas Program(ELAP)of the Government of Canada awarded a scholarship and the Institute of Integrative and Systems Biology(IBIS)of Laval University allowed the use of its campus and contributed to the training of the first author.
文摘The presence of heterozygous individuals in a population is crucial for maintaining genetic diversity,which can positively affect fitness and adaptability to environmental changes.While inbreeding generally reduces the proportion of heterozygous individuals in a population,polyploidy tends to increase the proportion.North American Populus tremuloides is one of the most widely distributed and ecologically important tree species in the Northern Hemisphere.However,genetic variation in Mexican populations of P.tremuloides,including the genetic signatures of their adaptation to a variety of environments,remains largely uncharacterized.The aim of this study was to analyze how inbreeding coefficient(FIS)and ploidy are associated with clonal richness,population cover,climate and soil traits in 91 marginal to small,isolated populations of this tree species throughout its entire distribution in Mexico.Genetic variables were determined using 36,810 filtered SNPs derived from genome re-sequencing.We found that FIS was approximately between 0 and e1,indicating an extreme heterozygosity excess.One key contributor to the observed extreme heterozygosity excess was asexual reproduction,although ploidy levels cannot explain this excess.Analysis of all neutral SNPs showed that asexual reproduction was positively correlated with observed heterozygosity(Ho)but negatively correlated with expected heterozygosity(He).Analysis of outlier SNPs also showed that asexual reproductionwas positively correlated with Ho and negatively correlated with He,although this latter correlation was not significant.These findings support the presence of a Meselson effect.
文摘The cultivation of Soledad pepper(Capsicum annuum L.)is essential in Oaxaca and Veracruz,but it faces issues with pests and diseases,which affect yield and cause economic losses.To mitigate these impacts,farmers have started using biostimulants such as chitosan and plant growth promoting bacteria instead of agrochemicals due to their environmental and health benefits.This study evaluated the effect of Bacillus subtilis and chitosan,both individually and combined,on the growth,yield,and fruit quality of Soledad pepper under greenhouse conditions.Four treatments were applied at different stages of the crop cycle:Q(Chitosan),BS(Bacillus subtilis),Q+BS(Chitosan+Bacillus subtilis),and T(Control).The results showed that the combination of chitosan and Bacillus subtilis significantly improved plant growth,especially in height and stem diameter.The chitosan treatment produced the highest number of fruits and plant weight,while the combination of chitosan and Bacillus subtilis enhanced fruit quality,increasing characteristics such as size,weight,pericarp thickness,and physicochemical parameters,notably in brix degrees,citric acid percentage,and pH,outperforming the individual treatments and the control.
基金Thanks to the Scientific Sub-direction of the Bogota BotanicalGarden in Colombia,which funded this research[Investment project No.1121,2016]In addition to ANID PhD fellowship,Chile[No.21190817,2019]Vicerrectoría de Investigacion,Desarrolloy Creacion Artística(VIDCA)grant from the Universidad Austral deChile[No.TD-2021-01,2021]awarded to KOZ.
文摘Recently,the Andean subparamo in Colombia has experienced severe wildfires,but little is known about the functional composition of recovering or not after a wildfire.Therefore,we examined the functional community composition subparamo affected byfire in 2016.We documented how functional traits changed 31 months after the disturbance and compared them with an unburned site.We sampled from one to two years after the fire every four months,then registered all recruits in 1655m plots.New individuals were classified into strategy functional groups based on the traits of persistence and dispersal.The first group was stem type and regeneration mechanism(seedling and resprout),and the second was fruit type and dispersal mode.We investigated the degree to which functional diversity changes plant communities over time(woody and non-woody),and we compared it with an unburned site.The most relevant results showed that resprouts and seed regenerated increased post-fire time and significant differences between sampling periods.The anemochory is the most relevant dispersal mode that indicates the community capacity to colonize the new gaps opened by the fire rapidly.We discuss how wildfire appears to be a triggering factor for persistence and dispersal strategy groups in subparamo burned given their characteristics of tolerance to stress.For this reason,a greater functional divergence between the ecosystems studied post-fire recovery has been related to higher levels of biodiversity at the landscape scale due to the high degree of endemism and significant differences in species composition between paramos.
文摘In this article, we study the ability of error-correcting quantum codes to increase the fidelity of quantum states throughout a quantum computation. We analyze arbitrary quantum codes that encode all qubits involved in the computation, and we study the evolution of n-qubit fidelity from the end of one application of the correcting circuit to the end of the next application. We assume that the correcting circuit does not introduce new errors, that it does not increase the execution time (i.e. its application takes zero seconds) and that quantum errors are isotropic. We show that the quantum code increases the fidelity of the states perturbed by quantum errors but that this improvement is not enough to justify the use of quantum codes. Namely, we prove that, taking into account that the time interval between the application of the two corrections is multiplied (at least) by the number of qubits n (due to the coding), the best option is not to use quantum codes, since the fidelity of the uncoded state over a time interval n times smaller is greater than that of the state resulting from the quantum code correction.
基金support provided by Co-mision Nacional de Investigacion Cientifica y Tecnologica(CONICYT),through FONDECYT project 1110 798:“Determinacion de indicadores geograficoambien-tales y de riesgo natural en el paisaje de La Araucania y Los Rios:Herramientas de soporte decisional para la planificacion y gestion territorial en sistemas costeros”.
文摘Coastal zones are very dynamic and fragile environments, constituting a landscape ever more heterogeneous, fragmented and with increasing levels of complexity due to the changing relationship between man and nature. Integrated coastal zone management therefore requires detailed knowledge of the system and its components, based—to a large extent—on technical and scientific information. However, the information generated must be in line with the political requirements necessary for decision-making and planning. Thus the use of indicators to give a simplified view of the many components of the territory, and at the same time to provide important information about patterns or trends, becomes a tool of the utmost importance. These indicators can be understood as measurable characteristics of the environment, which facilitate comprehension of the processes occurring at different scales and serve as a reference to inform the population and support decision-making. The aim of the present note is to demonstrate briefly the need to develop geographical-environmental and natural risk indicators to facilitate comprehension of the dynamic of spatial and temporal landscape patterns, particularly in coastal environments. This approach offers an historical summary of the natural, socio-economic and political processes which currently make up the territory, and which without doubt will continue to influence it in the future. At the same time, it is proposed that information should be integrated on the basis of this framework with a view to generating spatial decision support systems in a context of planning and integrated management of the coastal zones of Chile.
基金funding from the Spanish Ministry of Science, Innovation and Universities for project PID2023-149340OB-I00, “Ciencia abierta y ciencia ciudadana para una sociedad más sostenible e inclusiva: aportaciones del Sistema Universitario Espanol”
文摘Purpose:This paper focuses on scientific journals’policies on open access and open science.The subject has gained increasing relevance,driven by the need for more-democratic access to knowledge and improved research visibility,which require eliminating the financial,legal,and technical barriers that restrict access to scientific output.Design/methodology/approach:This paper uses the findings of FECYT’s 2023 Assessment of the Editorial and Scientific Quality of Spanish Scientific Journals,with 254 participating journals,as its case study.Open science indicators assess the transparency of policies on content access,reuse,openness,and reproducibility.Nonparametric tests analyse the relationship between the indicators and the dimensions of publisher type and subject area.Findings:High compliance rates are found for indicators related to publication licences and intellectual property rights.Only 37%of the journals examined post their editorial policy on Sherpa Romeo.Ninety-four percent publish open access.However,open peer review is rarely applied(0.38%of the journals).Journals in Communication,Information and Scientific Documentation,Fine Arts,Education Science,and Biomedical Sciences have high compliance percentages.Most journals(83%)are institutional,with universities and associations generally exhibiting better results.Research limitations:This study is based on specific indicators that do not cover all the factors that influence the transition toward open science;for example,editorial culture and technological infrastructure are not envisaged.Furthermore,differences in open science implementation are identified between disciplinary areas and between publisher types,but the underlying causes of these differences are not thoroughly investigated.Future research could address these points for a fuller understanding.Practical implications:This study highlights the need for journals to improve transparency by adopting open peer review and clear policies.These changes enhance accessibility and credibility,fostering inclusive knowledge dissemination.Institutions and policymakers should support these efforts to boost research impact.Originality/value:This study offers insights into open science practices in Spanish journals,a growing academic topic.Its originality lies in examining open science indicators across disciplines and publishers.By identifying strengths and gaps,the study helps journals enhance transparency.
基金Supported by the Founding Proyectos de Impulso a la Investigación to Hernandez-Nazara ZH from Universidad de Guadalajara,Mexico,No.PIN 2020-I.
文摘Obesity and type 2 diabetes mellitus(T2DM)are chronic pathologies with a high incidence worldwide.They share some pathological mechanisms,including hyperinsulinemia,the production and release of hormones,and hyperglycemia.The above,over time,affects other systems of the human body by causing tissue hypoxia,low-grade inflammation,and oxidative stress,which lay the pathophysiological groundwork for cancer.The leading causes of death globally are T2DM and cancer.Other main alterations of this pathological triad include the accumulation of advanced glycation end products and the release of endogenous alarmins due to cell death(i.e.,damage-associated molecular patterns)such as the intracellular proteins high-mobility group box protein 1 and protein S100 that bind to the receptor for advanced glycation products(RAGE)-a multiligand receptor involved in inflammatory and metabolic and neoplastic processes.This review analyzes the latest advanced reports on the role of RAGE in the development of obesity,T2DM,and cancer,with an aim to understand the intracellular signaling mechanisms linked with cancer initiation.This review also explores inflammation,oxidative stress,hypoxia,cellular senescence,RAGE ligands,tumor microenvironment changes,and the“cancer hallmarks”of the leading tumors associated with T2DM.The assimilation of this information could aid in the development of diagnostic and therapeutic approaches to lower the morbidity and mortality associated with these diseases.
文摘The“oil stain disease”has become a phytosanitary status that involves economic losses for farmers who produce gulupa(Passiflora edulis Sims).For this reason,this research aimed to evaluate the biocontrol activity of Bacillus subtilis ATCC 55033 in a culture medium based on fermented millet as a biocontrol product of the disease.Initially,metabolite production of seven strains of B.subtilis and a reference strain B.s(ATCC 55033)was evaluated;in addition,the in vitro antagonistic ability was evaluated against Xanthomonas axonopodis.Two experiments were performed under in vitro conditions:(1)study of the presence of halos of hemolysis due to metabolite production;(2)analysis of the antagonistic ability by using double layer.It was observed that concerning the average,a number five times bigger of halos of hemolysis and 10 times bigger halos of inhibition in vitro on the growth of X.axonopodis in the strains B.s(ATCC 55033)and B.s TB2 over other strains.Subsequently,the evaluation was performed under greenhouse conditions,based on a randomized block design,in which two treatments were applied over the soil:(1)application of the fermented medium based on millet with B.s ATCC 55033,24 h before X.a inoculation;(2)application of 5 d post-inoculation.It was observed that the treatment,previous infective process,obtained an average percentage of severity equal to 42.044%.In addition,after the evaluation month,a foliage restoration was presented.In conclusion,it is suggested that these products could act as inducers in the plant systemic resistance to trigger defense responses to infection of X.a.
基金supported by the National Council of Science and Technology of Mexico(CONACyT),which provided financial support through scholarships for postgraduate studies to J.L.G.S.(815176)and M.R.C.(507523)。
文摘The use of unmanned aerial vehicles(UAV)for forest monitoring has grown significantly in recent years,providing information with high spatial resolution and temporal versatility.UAV with multispectral sensors allow the use of indexes such as the normalized difference vegetation index(NDVI),which determines the vigor,physiological stress and photo synthetic activity of vegetation.This study aimed to analyze the spectral responses and variations of NDVI in tree crowns,as well as their correlation with climatic factors over the course of one year.The study area encompassed a 1.6-ha site in Durango,Mexico,where Pinus cembroides,Pinus engelmannii,and Quercus grisea coexist.Multispectral images were acquired with UAV and information on meteorological variables was obtained from NASA/POWER database.An ANOVA explored possible differences in NDVI among the three species.Pearson correlation was performed to identify the linear relationship between NDVI and meteorological variables.Significant differences in NDVI values were found at the genus level(Pinus and Quercus),possibly related to the physiological features of the species and their phenology.Quercus grisea had the lowest NDVI values throughout the year which may be attributed to its sensitivity to relative humidity and temperatures.Although the use of UAV with a multispectral sensor for NDVI monitoring allowed genera differentiation,in more complex forest analyses hyperspectral and LiDAR sensors should be integrated,as well other vegetation indexes be considered.
基金This work was partially funded by“Rufford Small Grants Foundation”(grant number 18815-1)Morris Animal Foundation(grant number D16ZO-413).
文摘Interspecific interactions are key drivers of individual and population-level fitness in a wide range of animals.However,in marine ecosystems,it is relatively unknown which biotic and abiotic factors impact behavioral interactions between competing species.We assessed the impact of weather,marine productivity,and population structure on the behavioral agonistic interactions between South American fur seals(SAFSs),Arctocephalus australis,and South American sea lions(SASLs),Otaria byronia,in a breeding colony of SAFS.We hypothesized that agonistic interactions between SAFSs and SASLs respond to biotic and abiotic factors such as SAFS population structure,marine productivity,and weather.We found that SASL and SAFS interactions almost always resulted in negative impacts on the social structure or reproductive success of the SAFS colony.SASL adult males initiated stampedes of SAFS and/or abducted and predated SAFS pups.Adult SAFS males abundance and severe weather events were negatively correlated with agonistic interactions between species.However,proxies for lower marine productivity such as higher sea surface temperature and lower catches of demerso-pelagic fish were the most important predictors of more frequent agonistic interactions between SAFS and SASL.Under the current scenario of decline in marine biomass due to global climate change and overfishing,agonistic interactions between competing marine predators could increase and exacerbate the negative impacts of environmental change in these species.
文摘Tropical mountain ranges shape the structure of tree communities and promote highly diverse natural habitats.The“Bosque Protector Chong on-Colonche”(BPCC),an 86,000-ha mountain formation situated on the coast of Ecuador,is biogeographically important for the region by connecting floristic elements of the wet Choco and the dry Tumbesian forests.Our understanding of the factors that model tree and palm diversity and distribution in this mountain range are limited.We measured and identified all trees and palms(DBH≥10 cm)in 289 plots of0.2 ha,distributed throughout BPCC.We used generalized linear models to explain the relationship between forest diversity and structure and climatic variables(temperature,rain,aridity),and altitude.We then used cluster and non-metric multidimensional scale(NMDS)analyses to search for distinct forest communities within the BPCC.Variance partition(varpart)was used to determine which predictor variables best explained these distinct forest communities.A species indicator analysis identified the species most likely to define these distinct forest communities.Finally,we carried out a niche modeling approach to identify the potential distribution of these forest communities within BPCC.In total,we identified 220 tree and palm species in our survey.The average number of species per plot was 17.8±5.8,ranging from 3 to 40 species.Classification methods sorted the 289study plots into six different forest communities,three communities in the dry forest and three in the semi-humid Garúa forest.Precipitation and temperature,but not altitude or aridity,explained floristic composition.These results emphasize the high but little cataloged diversity in the lowland mountain rainforests of coastal Ecuador.
文摘A highly acidic spill from one of the most important copper mines in the Americas (Buenavista del Cobre) occurred in Sonora, Mexico in August, 2014. 40,000 m3 of metals-enriched sulphate solution escaped into the Sonora River representing the worst ecological disaster in Mexican history. The spill affected the economy, water accessibility and the health of residents near the river. Despite the economic importance of mining in this area, no environmental assessment was undertaken. There is no information about the health impact of this event on the local population. The study assesses the health risk among children exposed to arsenic and mercury via groundwater in five communities located in a mining area into the Sonora River Basin, Mexico. Local drinking water from the localities was sampled one year after the spill and it was analyzed for arsenic and mercury by Atomic Absorption Spectrometry coupled with Hydride Generation (AAS/HG). Further, some of the traditional local foods were sampled and analyzed for the same elements. Results indicate that levels of arsenic in drinking water did not exceed the Mexican Norm (25 μg As/L) or the EPA Guideline (10 μg As/L). The concentrations of mercury exceeded the WHO and Mexican Legislation value (1.0 μg Hg/L). The Hazard Quotient (HQ) values for arsenic were >1 in 42% of children exposed and for mercury in 67% of the children. Foods concentrations contained in the ranges of 9.2 to 62.0 μg As/Kg and 0.28 to 42 μg Hg/Kg for arsenic and mercury respectively. These values are below the Codex Alimentarius limits. Children affected by mining activities are at risk of developing chronic diseases associated with low arsenic and mercury exposure via groundwater consumption, without consideration of the contribution from these metals by other important exposures routes.
文摘Objective. The host immune response is essential for restraining both HPV infections and HPV- related cervical cancer. We previously reported a direct correlation between proteolytic activity and malignant progression from precursor lesions to invasive cervical carcinoma. The present study was undertaken to investigate whether proteinases from cervical carcinoma extracts and representative purified proteinases involved in tumor progression could regulate lymphocyte proliferation to phytohemagglutinin (PHA) mitogen. Methods. Extracts were prepared from tissue samples obtained from patients with invasive cervical squamous carcinoma, squamous intra- epithelial lesions or women with normal cervix. Lymphocytes obtained from a single healthy donor were pre- incubated with one of these extracts in the presence or absence of proteinase inhibitors, and stimulated with PHA during 72 h. The proliferative response was measured using the 3- (4,5- dimethyl- thiazol- 2- yl)- 2,5- diphenyl- tetrazolium bromide (MTT) method (re- validated with thymidine uptake). Results. Lymphocyte proliferation was significantly decreased by cervical carcinoma extracts, while only slightly decreased by squamous intra- ep- ithelial lesions or normal extracts. Inhibitor assays indicated that proteinases from cervical carcinoma were responsible for 53.30% of total suppressive activity. We found that purified enzymes such as trypsin, cathepsin B, uPA and type IV collagenase suppressed the proliferative response in a dose- dependent fashion. Conclusions. Our data suggest that in addition to the classic role in tumor invasion, proteases could represent an immune evasion mechanism in cervical carcinoma.
基金supported by the“Agencia Estatal de Investigación(España)”,Spanish Ministry of Science,Innovation and Universities(grant refs.:PID2023-150663NB-C21 and PID2023-150663NB-C22/AEI/10.13039/501100011033)by the European Com-mission,projects“CLImate INTelligence:Extreme events detection,attribution and adaptation design using machine learning,CLINT”(grant ref.:H2020-LC-CLA-2020-2,101003876)+6 种基金“Test and Exper-iment Facilities for the Agri-Food Domain,AgriFoodTEF”(grant ref.:DIGITAL-2022-CLOUD-AI-02,101100622)by the ENIA International Chair in Agriculture,University of Córdoba(grant ref.:TSI-100921-2023-3)by the European Union through the European Regional De-velopment Fund“project IA-CONV”funded by the Community of Madrid through the grant agreement for the promotion and advance-ment of research and technology transfer at the University of Alcalá(grant ref.:CM/DEMG/2024-039)by the University of Córdoba through competitive grants for Andalusian society challenges(grant ref.:PP2F_L1_15)Antonio Manuel Gómez-Orellana has been supported by“Consejería de Transformación Económica,Industria,Conocimiento y Universidades de la Junta de Andalucía”(grant ref.:PREDOC-00489)David Guijo-Rubio has been supported by the“Agencia Estatal de Inves-tigación(España)”MCIU/AEI/10.13039/501100011033 and European Union NextGenerationEU/PRTR(grant ref.:JDC2022-048378-I)。
文摘This paper presents and evaluates two novel ordinal classification methods for wind speed prediction,considering three prediction time-horizons:1h,4h,and 8h.To address the problem,wind speed values are discretised into four classes,critical for wind farm management.Each class represents essential information for wind farm production,ranging from very low wind speeds to extreme wind speed events and the corresponding production conditions,facilitating operational decisions for wind farm operators.Ordinal classifiers are more suitable than nominal methods to tackle this problem.The study’s primary objective is to compare recently proposed ordinal classifiers for addressing the challenges of wind speed prediction with a focus on extreme wind conditions,which are responsible for many turbine shutdowns.Hourly wind speed measurements from a Spanish wind farm and predictor variables from the European Centre for Medium-Range Weather Forecasts Reanalysis v5(ERA5 Reanalysis)model are used.The proposed methods include an Artificial Neural Network(ANN)model implementing the Cumulative Link Model as an ordinal output function(MLP-CLM^(O)),which emphasises overall performance,and an ANN model optimised using a soft labelling technique based on triangular distributions(MLP-T^(O)),which excels at handling extreme class performance.The results demonstrate the superiority of both approaches over other nominal and ordinal methods across performance metrics that account for the unbalanced nature and ordinality of the data.MLP-CLMO excels in overall and ordinal performance,while MLP-TO demonstrates superior handling of the extreme class predictions.
基金Global wheat was directly supported by Analytics for the Australian Grains Industry(AAGI).
文摘Computer vision is increasingly used in farmers'fields and agricultural experiments to quantify important traits.Imaging setups with a sub-millimeter ground sampling distance enable the detection and tracking of plant features,including size,shape,and colour.Although today's AI-driven foundation models segment almost any object in an image,they still fail for complex plant canopies.To improve model performance,the global wheat dataset consortium assembled a diverse set of images from experiments around the globe.After the head detection dataset(GWHD),the new dataset targets a full semantic segmentation(GWFSS)of organs(leaves,stems and spikes)covering all developmental stages.Images were collected by 11 institutions using a wide range of imaging setups.Two datasets are provided:ⅰ)a set of 1096 diverse images in which all organs were labelled at the pixel level,and(ⅱ)a dataset of 52,078 images without annotations available for additional training.The labelled set was used to train segmentation models based on DeepLabV3Plus and Segformer.Our Segformer model performed slightly better than DeepLabV3Plus with a mIOU for leaves and spikes of ca.90%.However,the precision for stems with 54%was rather lower.The major advantages over published models are:ⅰ)the exclusion of weeds from the wheat canopy,ⅱ)the detection of all wheat features including necrotic and se-nescent tissues and its separation from crop residues.This facilitates further development in classifying healthy vs.unhealthy tissue to address the increasing need for accurate quantification of senescence and diseases in wheat canopies.
基金funded by DIUFRO No.DI20-0003 Project,Universidad de La Frontera。
文摘Chronic wounds are defined as wounds that fail to proceed through the normal phases of wound healing in an orderly and timely manner.The most common and inevitable impairment to wound healing is the installation of an infection,usually in the case of chronic wounds.Therefore,the objective of the present review was to identify the importance of copper nanoparticles in dressings for wound healing.Nanoparticles such as silver,gold and copper combat infectious processes through the inhibition of protein synthesis,peroxidation of the cell membrane and destroying the nucleic acids of bacteria and viruses.Among bioactive nanoparticles,copper plays a complex role in various cells,it modulates several cytokines and growth factor mechanisms of action and is essentially involved in all stages of the wound healing process.More importantly,copper plays a key role in skin regeneration and angiogenesis and accelerates the healing process through induction of vascular endothelial growth factor(VEGF)and angiogenesis by hypoxia-induced factor-1-alpha(HIF-1α)action where copper enhances HIF-1αexpression and HIF-1αbinding to the critical motifs in the promoter and putative enhancer regions of HIF-1-regulated genes.
基金support (doctoral scholarships) during the development ofthis review.
文摘Bats play crucial ecosystem services as seed dispersers,pollinators,controllers of insects,and nutrient recyclers.However,there has not been a thorough global review evaluating these roles in bats across all biogeographical regions of the world.We reviewed the literature published during the last two decades and identified 283 relevant studies:78 dealt with the control of potential insect pests by bats,80 related to the suppression of other arthropods,60 on the dispersal of native or endemic seeds,11 dealt with the dispersal of seeds of introduced plants,29 on the pollination of native or endemic plants,1 study on pollination of introduced plants,and 24 on the use of guano as fertilizer.Our literature search showed that queries combining the terms“seed dispersal,”“insectivorous bats,”“nectarivorous bats,”“use of guano,”and“ecosystem services”returned 577 studies,but half were experimental in nature.We found that the evaluation of ecosystem services by bats has been mostly conducted in the Neotropical and Palearctic regions.To detect differences across relevant studies,and to explain trends in the study of ecosystem services provided by bats,we performed generalized linear mixed models(GLMM)fitted with a Poisson distribution to analyze potential differences among sampling methods.We identified 409 bat species that provide ecosystem services,752 insect species consumed by bats and 549 plant species either dispersed or pollinated by bats.Our review summarizes the importance of conserving bat populations and the ecological services they provide,which is especially important during the current pandemic.
