This research investigates the potential of blending complementary lard oil with rubber seed oil as feedstock for biodiesel production.Rubber seed oil,obtained through hexane extraction using the Soxhlet method,contai...This research investigates the potential of blending complementary lard oil with rubber seed oil as feedstock for biodiesel production.Rubber seed oil,obtained through hexane extraction using the Soxhlet method,contains the major fatty acids of oleic acid(C_(18:1)),palmitic acid(C_(16:0)),linoleic acid(C_(18:2)),and stearic acid(C_(18:0)),while rubber seed oil primarily consists of linoleic acid(C_(18:2)),oleic acid(C_(18:1)),linolenic acid(C_(18:3)),palmitic acid(C_(16:0)),and stearic acid(C_(18:0)).The least acid value of lard oil(0.55 mg KOH/g)can benefit of reducing soap formation of rubber seed oil during transesterification process in biodiesel production due to its substantial-high acid value(16.28 mg KOH/g).Blending at ratios below 80:20 volume ratio produced biodiesel exceeding 85%,utilizing CaO as a catalyst.Lard oil demonstrated a higher reaction rate constant(11.88×10^(-3)min^(-1))than rubber seed oil(2.11×10^(-3)min^(-1)),indicating a significant difference in performance.High acid value and free fatty acids in rubber seed oil correlated with lower reaction rates.Maintaining a mixture ratio below 80:20 volume ratio optimized reaction rates during biodiesel production.Biodiesel obtained from blends below 80:20 volume ratio met ASTM D6751 and EN 14214 standards,demonstrating suitability for bio-auto fuel.The drawbacks of using rubber seed oil as a raw material for biodiesel production are overcome by blending with lard oil,giving rise to expanding renewable energy options for rural communities,community enterprises,and large-scale biodiesel production.展开更多
Obesity is usually considered as an overweight or excess body fat, leading to increased health problems. Obesity is a major risk factor for a number of serious diseases. Decreasing dietary fat absorption, through inhi...Obesity is usually considered as an overweight or excess body fat, leading to increased health problems. Obesity is a major risk factor for a number of serious diseases. Decreasing dietary fat absorption, through inhibition of pancreatic lipase activity, has been reported to be one of the most effective ways for managing obesity. The present study was aimed at investigating lipase inhibitors from edible plants. A lipase inhibitor was isolated from n-hexane and ethyl acetate extracts of the ripe fruits of Solanum stramonifolium Jacq. by column chromatography and identified by spectral analysis. Its structure was elucidated as (22R)-3β-benzoyloxy-22-hydroxy-4α-methyl-5α-stigmast-7-en-6-one or carpesterol (1). Carpesterol exhibited moderate lipase inhibition activity with IC50 value of 56.0 μg/mL while orlistat, a well- know pancreatic lipase inhibitor, had IC50 value of 3.5 ng/mL. Moreover, the kinetic properties of carpesterol on pancreatic lipase were evaluated. Carpesterol is a competitive inhibitor and exhibited antagonistic interaction when combined with orlistat on lipase inhibition activity.展开更多
The province of West Nusa Tenggara, which consists of Lombok Island and Sumbawa Island, has a stunning natural panoramic beauty, making it one of the main tourist destinations in Indonesia. The COVID</span><s...The province of West Nusa Tenggara, which consists of Lombok Island and Sumbawa Island, has a stunning natural panoramic beauty, making it one of the main tourist destinations in Indonesia. The COVID</span><span style="font-family:Verdana;">-</span><span style="font-family:Verdana;">19 outbreak has had an impact on the sluggishness of the tourism sector. This problem requires a solution. One alternative is to use the medicinal plant Sasambo (Sasak, Samawa, Mbojo) as an alternative to traditional health tourism. Data from community records, results of questionnaire responses, and scientific articles related to Sasambo traditional medicine show that there are various types of Sasambo medicinal plants that have the potential as an alternative to traditional health tourism with details, Lombok (Sasak) 43 species, Sumbawa (Samawa) 25 species, and Bima (Mbojo) 35 species. Some of these plant species are used for the treatment of diseases caused by viruses. The islands of Lombok and Sumbawa have abundant medicinal plants, making the two islands a potential destination for traditional health tourism.展开更多
Mn-doped ZnO samples,Zn_(1-x)Mn_(x)O(x=0,0.01,0.03 and 0.05;mole fraction),were successfully synthesized by sonochemical method.The undoped and Mn-doped Zn O samples were characterized by X-ray diffraction(XRD),scanni...Mn-doped ZnO samples,Zn_(1-x)Mn_(x)O(x=0,0.01,0.03 and 0.05;mole fraction),were successfully synthesized by sonochemical method.The undoped and Mn-doped Zn O samples were characterized by X-ray diffraction(XRD),scanning electron microscopy(SEM),transmission electron microscopy(TEM),and Raman spectroscopy.XRD patterns of all products are identified to hexagonal wurtzite Zn O structure and their three main peaks shift toward lower diffraction angles due to the incorporation of Mn^(2+)into Zn O crystal lattice.The morphologies of Zn_(1-x)Mn_(x)O(x=0,0.01,0.03 and 0.05)were examined by SEM and TEM.The undoped Zn O sample shows large-scale uniform microflowers which are broken into nanorods and nanoparticles by Mn dopant.Their magnetic properties were investigated by a vibrating sample magnetometer at room temperature.The magnetization-applied field behavior of undoped Zn O defines its weak ferromagnetic behavior.The 3 mol%Mn-doped Zn O shows the highest saturation magnetization of 51.73910^(-3)m A·m^(2)·g^(-1),and the 5 mol%Mn-doped Zn O has suppressed ferromagnetic property due to the formation of Mn clusters inside.展开更多
Artocarpus odoratissimus, Terep (Sasak), is traditionally used as a malarian drug. As chemotacsomomy analisys,?A. odoratissimus contains flavonoids. This experiment involves the isolation of flavonoid from A. odoratis...Artocarpus odoratissimus, Terep (Sasak), is traditionally used as a malarian drug. As chemotacsomomy analisys,?A. odoratissimus contains flavonoids. This experiment involves the isolation of flavonoid from A. odoratissimus. Isolation of flavonoid in A. odoratissimus could be performed using methanol as extracting solvent, and gravitational column chromatography was used to isolate flavonoid in pure form the extract. The characteristic of flavonoid from A. odoratissimus could be studied in undergraduate course.展开更多
<span style="font-family:Verdana;">The development of tourism is currently a priority for governments in Indonesia, especially the Sumbawa Island. Tourism begins to glance at other sectors or areas not...<span style="font-family:Verdana;">The development of tourism is currently a priority for governments in Indonesia, especially the Sumbawa Island. Tourism begins to glance at other sectors or areas not only about the natural scenery but also begins to extend to traditional health tourism by taking advantage of local culturally based local medicinal plants. Considering in Indonesia, especially the Sumbawa Island have an abundance of medicinal plants. It has been promoted as one of the first steps in promoting tourism. The effort and measures involved the use of Sumbawa Oil that is known to have many medicinal properties and to be popular in the community because it has proved capable of being a cure. Sumbawa oil is one of the superior products of the Sumbawa Island which is produced by local communities by utilizing the surrounding natural resources. This oil is not just a traditional medicine but also a local culture obtained from ancestors. All production processes, from the selection of raw materials to processing are carried out based on knowledge from generation </span><span style="font-family:Verdana;">to generation. Some producers even have traditional rituals performed during processing. This traditional ritual is believed to be able to increase the medi</span><span style="font-family:Verdana;">cinal properties of Sumbawa oil. Sumbawa Oil could be a flagship for by-products and traditional medicated educationers that could boost the desire of tourists to visit the Sumbawa Island.展开更多
This paper investigates the concept of Cross Polarization (CP) experiment in addition to revisiting the two potential expansion schemes recently developed in the field of solid-state nuclear magnetic resonance (SSNMR)...This paper investigates the concept of Cross Polarization (CP) experiment in addition to revisiting the two potential expansion schemes recently developed in the field of solid-state nuclear magnetic resonance (SSNMR): namely, the Floquet-Magnus expansion and the Fer expansion. We use the aforementioned expansion schemes for the calculation of effective Hamiltonians and propagators when the spin system undergoes Cross Polarization radiation. CP is the gateway experiment into SSNMR. An in-depth comprehension of the underlying mechanics of spin dynamics during the cross-polarization experiment is pivotal for further experimental developments and optimization of more complex solid-state NMR experiments. The main contribution of this work is a prospect related to spin physics;particularly regarding to generalization of the calculation. This work reports original yet interesting novel ideas and developments that include calculations performed on the CP experiment. In fact, the approach presented could play a major role in the interpretation of several fine NMR experiments in solids, which would in turn provide significant new insights in spin physics. The generality of the work points towards potential applications in problems related in solid-state NMR and theoretical developments of spectroscopy as well as interdisciplinary research areas as long as they include spin dynamics concepts.展开更多
Waste generation from food manufacturing facilities poses a serious hazard like environmental degradation, water pollution, and land pollution due to its high nutrient composition. Specifically, solid waste(powder) di...Waste generation from food manufacturing facilities poses a serious hazard like environmental degradation, water pollution, and land pollution due to its high nutrient composition. Specifically, solid waste(powder) disposal requires additional energy sources in terms of scientific treatment, structured collection, and disposal packaging according to the safety regulation. Thus, this research discusses the viewpoint of integrating food processing waste as an organic carbon source with BG-11 medium for Chlorella vulgaris(FSP-E) growth. The food processing waste powders investigated in this study were obtained from milk, and biscuit manufacturing facilities. The culture medium was modified by combining both BG-11 and food processing waste powders to identify the optimal algal growth and biochemical content.Compared to the microalgae grown in BG-11 alone(IBG), the combination of biscuit waste and IBG produced higher biomass concentration(44%), with increased lipid(11%), protein(20%), and carbohydrate(57%) contents. Chlorella vulgaris was able to uptake nutrients from the culture medium with combination of food processing waste and IBG thus enhancing its growth. The results obtained also indicate that an integrated culture system using food processing waste and synthetic sources can generate energy out of waste by improving the bio-composition of the microalgae biomass.展开更多
Bismuth antimony telluride(Bi_(2–x)Sb_(x)Te_(3))is commonly used for thermoelectric generation at temperatures near ambient temperature.Here,we report incorporating reduced graphene oxide(rGO)and Cu_(2)Se_(0.98)Te_(0...Bismuth antimony telluride(Bi_(2–x)Sb_(x)Te_(3))is commonly used for thermoelectric generation at temperatures near ambient temperature.Here,we report incorporating reduced graphene oxide(rGO)and Cu_(2)Se_(0.98)Te_(0.02) into the Bi_(0.5)Sb_(1.5)Te_(3)(BST)(rGO/Bi_(0.5)Sb_(1.5)Te_(3-x)Cu_(2)Se_(0.98)Te_(0.02),where x=0.0%,0.1%,0.3%,0.5% and 1.0%,in mass)synthesized by a solid-state technique.The dispersion of rGO and Cu_(2)Se_(0.98)Te_(0.02) into the BST matrix improved carrier transport properties at the grain boundary interfaces and reduced thermal conductivity.Strong electron scattering at large interface barriers was responsible for increased electrical conductivity.The bulk sample of rGO/BST-0.3%Cu_(2)Se_(0.98)Te_(0.02)(in mass)possessed a low thermal conductivity of 0.76 W·m^(−1)·K^(−1) at 497 K.Enhanced phonon scattering at grain boundaries between BST and rGO/Cu_(2)Se_(0.98)Te_(0.02) caused a low thermal conductivity.At 448 K,the highest zT value for rGO/BST-0.3% Cu_(2)Se_(0.98)Te_(0.02)(in mass)was 1.64,which is 37% higher than the zT value for pure BST(zT=1.19).Results suggested that incorporating rGO and Cu_(2)Se_(0.98)Te_(0.02) into the BST matrix effectively improved thermoelectric power generation.展开更多
Low water solubility leading to poor bioavailability has an impact on the decreasing of curcumin uptake in the body,resulting in a deficiency of its medicinal benefits.This study aims to overcome the limitations of cu...Low water solubility leading to poor bioavailability has an impact on the decreasing of curcumin uptake in the body,resulting in a deficiency of its medicinal benefits.This study aims to overcome the limitations of curcumin by formulating a nano-emulsion called curcumin emulsion(CE).Furthermore,in order to improve the physi-cochemical properties and drug release features,the CE was encapsulated within chitosan-assembled mesoporous silica nanoparticles(Chi@SiO_(2)@CE).This material was prepared using a one-pot method and was characterized by Attenuated-total reflectance(ATR-FTIR),Particle Size Analyzer(PSA),Thermogravimetric analysis(TGA),N_(2)adsorption-desorption,Scanning Electron Microscopy(SEM),and Transmission Electron Microscopy(TEM).Additionally,antioxidant activity and in vitro drug release were also conducted.The study demonstrated that CE has strong antioxidant activity(IC_(50)=14.14μM)compared to curcumin alone.Additionally,the Chi@SiO_(2)@CE exhibited pH-controlled release behavior,with less than 20%release of curcumin under an artificial gastric environment and 50%release under pH 7.4 conditions within 24 h.Therefore,this research suggest that Chi@SiO_(2)@CE material has potential as a pH-responsive drug delivery material.展开更多
Numerous endeavours have been developed bio-based polymer packaging films to replace the use of petroleum-based packaging.In this study,as a response and support to the enduring research issues,we have developed the o...Numerous endeavours have been developed bio-based polymer packaging films to replace the use of petroleum-based packaging.In this study,as a response and support to the enduring research issues,we have developed the optimization composite film formulation based on chitosan(2%),Dioscorea alata starch(0.5%),and glycerol(1.5%)had satisfactory result on several parameters consisting thickness(0.45 mm),solubility(472.1%),moisture content(29.872%),biodegradability(38.346%),elastic modulus(971.2 N/m2)and tensile strength(98.71 N/m).Further,the optimized chitosan film(CF)formulation was enriched with several essential oils(EO),i.e.,lemongrass,garlic and aloe vera oil.Upon the addition of EO,the solubility,biodegradable tests,and elongation to break of CF tended to decrease whereas the contact angle and mechanical properties significantly increased.Finally,the antibacterial properties of CF against Escherichia coli,Salmonella typhi,Staphylococcus aureus and Staphylococcus epidermidis dramatically increased by the addition of EO.These impressive results are expected to be applied in the food packaging industry to maintain the quality of food products.展开更多
基金financially supported by the Research and Development Institute at Sakon Nakhon Rajabhat University,as well as by the National Research Council of Thailand(NRCT)(N42A650196).
文摘This research investigates the potential of blending complementary lard oil with rubber seed oil as feedstock for biodiesel production.Rubber seed oil,obtained through hexane extraction using the Soxhlet method,contains the major fatty acids of oleic acid(C_(18:1)),palmitic acid(C_(16:0)),linoleic acid(C_(18:2)),and stearic acid(C_(18:0)),while rubber seed oil primarily consists of linoleic acid(C_(18:2)),oleic acid(C_(18:1)),linolenic acid(C_(18:3)),palmitic acid(C_(16:0)),and stearic acid(C_(18:0)).The least acid value of lard oil(0.55 mg KOH/g)can benefit of reducing soap formation of rubber seed oil during transesterification process in biodiesel production due to its substantial-high acid value(16.28 mg KOH/g).Blending at ratios below 80:20 volume ratio produced biodiesel exceeding 85%,utilizing CaO as a catalyst.Lard oil demonstrated a higher reaction rate constant(11.88×10^(-3)min^(-1))than rubber seed oil(2.11×10^(-3)min^(-1)),indicating a significant difference in performance.High acid value and free fatty acids in rubber seed oil correlated with lower reaction rates.Maintaining a mixture ratio below 80:20 volume ratio optimized reaction rates during biodiesel production.Biodiesel obtained from blends below 80:20 volume ratio met ASTM D6751 and EN 14214 standards,demonstrating suitability for bio-auto fuel.The drawbacks of using rubber seed oil as a raw material for biodiesel production are overcome by blending with lard oil,giving rise to expanding renewable energy options for rural communities,community enterprises,and large-scale biodiesel production.
文摘Obesity is usually considered as an overweight or excess body fat, leading to increased health problems. Obesity is a major risk factor for a number of serious diseases. Decreasing dietary fat absorption, through inhibition of pancreatic lipase activity, has been reported to be one of the most effective ways for managing obesity. The present study was aimed at investigating lipase inhibitors from edible plants. A lipase inhibitor was isolated from n-hexane and ethyl acetate extracts of the ripe fruits of Solanum stramonifolium Jacq. by column chromatography and identified by spectral analysis. Its structure was elucidated as (22R)-3β-benzoyloxy-22-hydroxy-4α-methyl-5α-stigmast-7-en-6-one or carpesterol (1). Carpesterol exhibited moderate lipase inhibition activity with IC50 value of 56.0 μg/mL while orlistat, a well- know pancreatic lipase inhibitor, had IC50 value of 3.5 ng/mL. Moreover, the kinetic properties of carpesterol on pancreatic lipase were evaluated. Carpesterol is a competitive inhibitor and exhibited antagonistic interaction when combined with orlistat on lipase inhibition activity.
文摘The province of West Nusa Tenggara, which consists of Lombok Island and Sumbawa Island, has a stunning natural panoramic beauty, making it one of the main tourist destinations in Indonesia. The COVID</span><span style="font-family:Verdana;">-</span><span style="font-family:Verdana;">19 outbreak has had an impact on the sluggishness of the tourism sector. This problem requires a solution. One alternative is to use the medicinal plant Sasambo (Sasak, Samawa, Mbojo) as an alternative to traditional health tourism. Data from community records, results of questionnaire responses, and scientific articles related to Sasambo traditional medicine show that there are various types of Sasambo medicinal plants that have the potential as an alternative to traditional health tourism with details, Lombok (Sasak) 43 species, Sumbawa (Samawa) 25 species, and Bima (Mbojo) 35 species. Some of these plant species are used for the treatment of diseases caused by viruses. The islands of Lombok and Sumbawa have abundant medicinal plants, making the two islands a potential destination for traditional health tourism.
基金financially supported by the National Research University(NRU)Project for Chiang Mai UniversityBansomdejchaopraya Rajabhat University(BSRU)Research Fund。
文摘Mn-doped ZnO samples,Zn_(1-x)Mn_(x)O(x=0,0.01,0.03 and 0.05;mole fraction),were successfully synthesized by sonochemical method.The undoped and Mn-doped Zn O samples were characterized by X-ray diffraction(XRD),scanning electron microscopy(SEM),transmission electron microscopy(TEM),and Raman spectroscopy.XRD patterns of all products are identified to hexagonal wurtzite Zn O structure and their three main peaks shift toward lower diffraction angles due to the incorporation of Mn^(2+)into Zn O crystal lattice.The morphologies of Zn_(1-x)Mn_(x)O(x=0,0.01,0.03 and 0.05)were examined by SEM and TEM.The undoped Zn O sample shows large-scale uniform microflowers which are broken into nanorods and nanoparticles by Mn dopant.Their magnetic properties were investigated by a vibrating sample magnetometer at room temperature.The magnetization-applied field behavior of undoped Zn O defines its weak ferromagnetic behavior.The 3 mol%Mn-doped Zn O shows the highest saturation magnetization of 51.73910^(-3)m A·m^(2)·g^(-1),and the 5 mol%Mn-doped Zn O has suppressed ferromagnetic property due to the formation of Mn clusters inside.
文摘Artocarpus odoratissimus, Terep (Sasak), is traditionally used as a malarian drug. As chemotacsomomy analisys,?A. odoratissimus contains flavonoids. This experiment involves the isolation of flavonoid from A. odoratissimus. Isolation of flavonoid in A. odoratissimus could be performed using methanol as extracting solvent, and gravitational column chromatography was used to isolate flavonoid in pure form the extract. The characteristic of flavonoid from A. odoratissimus could be studied in undergraduate course.
文摘<span style="font-family:Verdana;">The development of tourism is currently a priority for governments in Indonesia, especially the Sumbawa Island. Tourism begins to glance at other sectors or areas not only about the natural scenery but also begins to extend to traditional health tourism by taking advantage of local culturally based local medicinal plants. Considering in Indonesia, especially the Sumbawa Island have an abundance of medicinal plants. It has been promoted as one of the first steps in promoting tourism. The effort and measures involved the use of Sumbawa Oil that is known to have many medicinal properties and to be popular in the community because it has proved capable of being a cure. Sumbawa oil is one of the superior products of the Sumbawa Island which is produced by local communities by utilizing the surrounding natural resources. This oil is not just a traditional medicine but also a local culture obtained from ancestors. All production processes, from the selection of raw materials to processing are carried out based on knowledge from generation </span><span style="font-family:Verdana;">to generation. Some producers even have traditional rituals performed during processing. This traditional ritual is believed to be able to increase the medi</span><span style="font-family:Verdana;">cinal properties of Sumbawa oil. Sumbawa Oil could be a flagship for by-products and traditional medicated educationers that could boost the desire of tourists to visit the Sumbawa Island.
文摘This paper investigates the concept of Cross Polarization (CP) experiment in addition to revisiting the two potential expansion schemes recently developed in the field of solid-state nuclear magnetic resonance (SSNMR): namely, the Floquet-Magnus expansion and the Fer expansion. We use the aforementioned expansion schemes for the calculation of effective Hamiltonians and propagators when the spin system undergoes Cross Polarization radiation. CP is the gateway experiment into SSNMR. An in-depth comprehension of the underlying mechanics of spin dynamics during the cross-polarization experiment is pivotal for further experimental developments and optimization of more complex solid-state NMR experiments. The main contribution of this work is a prospect related to spin physics;particularly regarding to generalization of the calculation. This work reports original yet interesting novel ideas and developments that include calculations performed on the CP experiment. In fact, the approach presented could play a major role in the interpretation of several fine NMR experiments in solids, which would in turn provide significant new insights in spin physics. The generality of the work points towards potential applications in problems related in solid-state NMR and theoretical developments of spectroscopy as well as interdisciplinary research areas as long as they include spin dynamics concepts.
基金supported by the Fundamental Research Grant Scheme, Malaysia (No. FRGS/1/2019/STG05/UNIM/02/2)My PAIR-PHCHibiscus Grant (No. My PAIR/1/2020/STG05/UNIM/1)supported by the National Natural Science Foundation of China (No. 41876124)。
文摘Waste generation from food manufacturing facilities poses a serious hazard like environmental degradation, water pollution, and land pollution due to its high nutrient composition. Specifically, solid waste(powder) disposal requires additional energy sources in terms of scientific treatment, structured collection, and disposal packaging according to the safety regulation. Thus, this research discusses the viewpoint of integrating food processing waste as an organic carbon source with BG-11 medium for Chlorella vulgaris(FSP-E) growth. The food processing waste powders investigated in this study were obtained from milk, and biscuit manufacturing facilities. The culture medium was modified by combining both BG-11 and food processing waste powders to identify the optimal algal growth and biochemical content.Compared to the microalgae grown in BG-11 alone(IBG), the combination of biscuit waste and IBG produced higher biomass concentration(44%), with increased lipid(11%), protein(20%), and carbohydrate(57%) contents. Chlorella vulgaris was able to uptake nutrients from the culture medium with combination of food processing waste and IBG thus enhancing its growth. The results obtained also indicate that an integrated culture system using food processing waste and synthetic sources can generate energy out of waste by improving the bio-composition of the microalgae biomass.
基金This research has received funding support from the National Science,Research and Innovation Fund(NSRF)via the Program Management Unit for Human Resources&Institutional Development,Research and Innovation[grant number B05F640150],Thailand.
文摘Bismuth antimony telluride(Bi_(2–x)Sb_(x)Te_(3))is commonly used for thermoelectric generation at temperatures near ambient temperature.Here,we report incorporating reduced graphene oxide(rGO)and Cu_(2)Se_(0.98)Te_(0.02) into the Bi_(0.5)Sb_(1.5)Te_(3)(BST)(rGO/Bi_(0.5)Sb_(1.5)Te_(3-x)Cu_(2)Se_(0.98)Te_(0.02),where x=0.0%,0.1%,0.3%,0.5% and 1.0%,in mass)synthesized by a solid-state technique.The dispersion of rGO and Cu_(2)Se_(0.98)Te_(0.02) into the BST matrix improved carrier transport properties at the grain boundary interfaces and reduced thermal conductivity.Strong electron scattering at large interface barriers was responsible for increased electrical conductivity.The bulk sample of rGO/BST-0.3%Cu_(2)Se_(0.98)Te_(0.02)(in mass)possessed a low thermal conductivity of 0.76 W·m^(−1)·K^(−1) at 497 K.Enhanced phonon scattering at grain boundaries between BST and rGO/Cu_(2)Se_(0.98)Te_(0.02) caused a low thermal conductivity.At 448 K,the highest zT value for rGO/BST-0.3% Cu_(2)Se_(0.98)Te_(0.02)(in mass)was 1.64,which is 37% higher than the zT value for pure BST(zT=1.19).Results suggested that incorporating rGO and Cu_(2)Se_(0.98)Te_(0.02) into the BST matrix effectively improved thermoelectric power generation.
基金Directorate General of Higher Education,Ministry of Education,Culture,Research and Technology,Indonesia for funding this research through Program Kreativitas Mahasiswa(PKM)2021(No.1949/E2/KM.05.01/2021)partially supported by Universitas Sebelas Maret through Pene-litian Unggulan Terapan(PUT)2021 research scheme(No.260/UN27.22/HK.07.00/2021).
文摘Low water solubility leading to poor bioavailability has an impact on the decreasing of curcumin uptake in the body,resulting in a deficiency of its medicinal benefits.This study aims to overcome the limitations of curcumin by formulating a nano-emulsion called curcumin emulsion(CE).Furthermore,in order to improve the physi-cochemical properties and drug release features,the CE was encapsulated within chitosan-assembled mesoporous silica nanoparticles(Chi@SiO_(2)@CE).This material was prepared using a one-pot method and was characterized by Attenuated-total reflectance(ATR-FTIR),Particle Size Analyzer(PSA),Thermogravimetric analysis(TGA),N_(2)adsorption-desorption,Scanning Electron Microscopy(SEM),and Transmission Electron Microscopy(TEM).Additionally,antioxidant activity and in vitro drug release were also conducted.The study demonstrated that CE has strong antioxidant activity(IC_(50)=14.14μM)compared to curcumin alone.Additionally,the Chi@SiO_(2)@CE exhibited pH-controlled release behavior,with less than 20%release of curcumin under an artificial gastric environment and 50%release under pH 7.4 conditions within 24 h.Therefore,this research suggest that Chi@SiO_(2)@CE material has potential as a pH-responsive drug delivery material.
基金This work has been financially supported through Penelitian Dasar Unggulan Perguruan Tinggi 2021(221.1/UN27.22/HK.07.00/2021)by Ministry of Research,Technology and Higher Education,Indonesia。
文摘Numerous endeavours have been developed bio-based polymer packaging films to replace the use of petroleum-based packaging.In this study,as a response and support to the enduring research issues,we have developed the optimization composite film formulation based on chitosan(2%),Dioscorea alata starch(0.5%),and glycerol(1.5%)had satisfactory result on several parameters consisting thickness(0.45 mm),solubility(472.1%),moisture content(29.872%),biodegradability(38.346%),elastic modulus(971.2 N/m2)and tensile strength(98.71 N/m).Further,the optimized chitosan film(CF)formulation was enriched with several essential oils(EO),i.e.,lemongrass,garlic and aloe vera oil.Upon the addition of EO,the solubility,biodegradable tests,and elongation to break of CF tended to decrease whereas the contact angle and mechanical properties significantly increased.Finally,the antibacterial properties of CF against Escherichia coli,Salmonella typhi,Staphylococcus aureus and Staphylococcus epidermidis dramatically increased by the addition of EO.These impressive results are expected to be applied in the food packaging industry to maintain the quality of food products.
