6.1 Vasopressors Epinephrine (adrenaline) is an endogenous catecholamine with potent alpha and beta stimulating properties. The alpha-adrenergic action (vasoconstriction) increases systemic and pulmonary vascular resi...6.1 Vasopressors Epinephrine (adrenaline) is an endogenous catecholamine with potent alpha and beta stimulating properties. The alpha-adrenergic action (vasoconstriction) increases systemic and pulmonary vascular resistance, increasing both systolic and diastolic blood pressure. The rise in diastolic blood pressure directly increases coronary perfusion pressure, thereby increasing coronary blood flow and increasing the likelihood of return of spontaneous circulation. Epinephrine also increases cerebral blood flow during CPR because peripheralgreater proportion of flowvasoconstriction directs a to the cerebral circulation.展开更多
文摘6.1 Vasopressors Epinephrine (adrenaline) is an endogenous catecholamine with potent alpha and beta stimulating properties. The alpha-adrenergic action (vasoconstriction) increases systemic and pulmonary vascular resistance, increasing both systolic and diastolic blood pressure. The rise in diastolic blood pressure directly increases coronary perfusion pressure, thereby increasing coronary blood flow and increasing the likelihood of return of spontaneous circulation. Epinephrine also increases cerebral blood flow during CPR because peripheralgreater proportion of flowvasoconstriction directs a to the cerebral circulation.
