The infection of H. pylori was conventionally diagnosed by microscope identification and isolation ofthe pathogen by culture. However, these procedures are fairly time consuming and not sensitive enough. We have devel...The infection of H. pylori was conventionally diagnosed by microscope identification and isolation ofthe pathogen by culture. However, these procedures are fairly time consuming and not sensitive enough. We have developed highly sensitive and specific method to detect the infection by PCR based amplification of nucleicacid. Using this procedure, we are studying the molecular aspect of this particular pathogen. The genetic analysis of clarithromycin resistant strain revealed that the appearance of resistant strain is not due to the conversion from sensitive strain to resistant,展开更多
文摘The infection of H. pylori was conventionally diagnosed by microscope identification and isolation ofthe pathogen by culture. However, these procedures are fairly time consuming and not sensitive enough. We have developed highly sensitive and specific method to detect the infection by PCR based amplification of nucleicacid. Using this procedure, we are studying the molecular aspect of this particular pathogen. The genetic analysis of clarithromycin resistant strain revealed that the appearance of resistant strain is not due to the conversion from sensitive strain to resistant,
