In a recent study published in Nature Biotechnology,Mohammad Ghazi Vakili et al.applied quantum computing and generative machine learning-specifically Quantum Circuit Born Machines(QCBMs)and Long Short-Term Memory(LST...In a recent study published in Nature Biotechnology,Mohammad Ghazi Vakili et al.applied quantum computing and generative machine learning-specifically Quantum Circuit Born Machines(QCBMs)and Long Short-Term Memory(LSTM)networks—to efficiently explore high-dimensional chemical space and identify structurally novel KRAs inhibitors.This research highlights how quantum-enhanced Al(artificial intelligence),when supported by substantial pre-existing data,can contribute to the discovery of inhibitors for challenging targets such as KRAs.展开更多
In a groundbreaking study recently published in Nature,Kai-Shan Tao and colleagues achieved the first successful heterotopic pigto-human liver xenotransplantation using a gene-edited Bama miniature pig carrying six ta...In a groundbreaking study recently published in Nature,Kai-Shan Tao and colleagues achieved the first successful heterotopic pigto-human liver xenotransplantation using a gene-edited Bama miniature pig carrying six targeted genetic modifications designed to suppress immunologic rejection and thrombosis.1 The ability of the graft to maintain bile secretion,albumin synthesis,and histological integrity over 10 days in a brain-dead human recipient underscores the potential of xenotransplantation as a viable solution to the global shortage of donor livers for patients with acute or end-stage liver failure.展开更多
A recent study published in Science by Hyunjoon Kim and colleagues has established the world’s most comprehensive bat organoid platform,marking a significant advancement in comparative virology and pandemic preparedn...A recent study published in Science by Hyunjoon Kim and colleagues has established the world’s most comprehensive bat organoid platform,marking a significant advancement in comparative virology and pandemic preparedness research.1 This innovative research addresses critical knowledge gaps in zoonotic disease transmission by developing sophisticated laboratory models that closely mimic bat tissues.展开更多
基金supported by the KRIBB Research Initiative Program(KGM4252533,KGM5162524)supported by a Korea Basic Science Institute grant(H.J.C.,AC202402).
文摘In a recent study published in Nature Biotechnology,Mohammad Ghazi Vakili et al.applied quantum computing and generative machine learning-specifically Quantum Circuit Born Machines(QCBMs)and Long Short-Term Memory(LSTM)networks—to efficiently explore high-dimensional chemical space and identify structurally novel KRAs inhibitors.This research highlights how quantum-enhanced Al(artificial intelligence),when supported by substantial pre-existing data,can contribute to the discovery of inhibitors for challenging targets such as KRAs.
基金supported by the KRIBB Research Initiative Program(KGM4252533,PRM2122523,KGM5162524)the National Research Council of Science&Technology(NST)grant funded by the Korea government(MSIT)(No.GTL24021-000).
文摘In a groundbreaking study recently published in Nature,Kai-Shan Tao and colleagues achieved the first successful heterotopic pigto-human liver xenotransplantation using a gene-edited Bama miniature pig carrying six targeted genetic modifications designed to suppress immunologic rejection and thrombosis.1 The ability of the graft to maintain bile secretion,albumin synthesis,and histological integrity over 10 days in a brain-dead human recipient underscores the potential of xenotransplantation as a viable solution to the global shortage of donor livers for patients with acute or end-stage liver failure.
基金supported by the KRIBB Research Initiative Program(KGM4252533,KGM5162524,KGM5362521)the National Research Foundation(NRF)funded by the Korean government(MSIT)(RS-2021-NR057659)the National Research Council of Science&Technology(NST)grant by the Korean government(MSIT)(No.GTL24021-000).
文摘A recent study published in Science by Hyunjoon Kim and colleagues has established the world’s most comprehensive bat organoid platform,marking a significant advancement in comparative virology and pandemic preparedness research.1 This innovative research addresses critical knowledge gaps in zoonotic disease transmission by developing sophisticated laboratory models that closely mimic bat tissues.
