Pedestrian detection has been a hot spot in computer vision over the past decades due to the wide spectrum of promising applications,and the major challenge is false positives that occur during pedestrian detection.Th...Pedestrian detection has been a hot spot in computer vision over the past decades due to the wide spectrum of promising applications,and the major challenge is false positives that occur during pedestrian detection.The emergence of various Convolutional Neural Network-based detection strategies substantially enhances pedestrian detection accuracy but still does not solve this problem well.This paper deeply analyzes the detection framework of the two-stage CNN detection methods and finds out false positives in detection results are due to its training strategy misclassifying some false proposals,thus weakening the classification capability of the following subnetwork and hardly suppressing false ones.To solve this problem,this paper proposes a pedestrian-sensitive training algorithm to help two-stage CNN detection methods effectively learn to distinguish the pedestrian and non-pedestrian samples and suppress the false positives in the final detection results.The core of the proposed algorithm is to redesign the training proposal generating scheme for the two-stage CNN detection methods,which can avoid a certain number of false ones that mislead its training process.With the help of the proposed algorithm,the detection accuracy of the MetroNext,a smaller and more accurate metro passenger detector,is further improved,which further decreases false ones in its metro passenger detection results.Based on various challenging benchmark datasets,experiment results have demonstrated that the feasibility of the proposed algorithm is effective in improving pedestrian detection accuracy by removing false positives.Compared with the existing state-of-the-art detection networks,PSTNet demonstrates better overall prediction performance in accuracy,total number of parameters,and inference time;thus,it can become a practical solution for hunting pedestrians on various hardware platforms,especially for mobile and edge devices.展开更多
Background:This study investigated the relationship between meteorological factors and daily outpatient visits to rabies post-exposure prophylaxis clinics to inform animal injury prevention strategies.Methods:Daily ou...Background:This study investigated the relationship between meteorological factors and daily outpatient visits to rabies post-exposure prophylaxis clinics to inform animal injury prevention strategies.Methods:Daily outpatient visit data from rabies post-exposure prophylaxis clinics in Jinan and corresponding meteorological data were collected from January 1,2020,to December 31,2022.A generalized additive model was used to quantitatively assess the relationship between these factors.A total of 202,010 patients visited these clinics during this period.Results:Daily mean,maximum,and minimum temperatures,and relative humidity were positively associated with outpatient visits.A 1°C increase in mean,maximum,and minimum temperatures corresponded to increases in daily visits of 1.65%(95%Confidence Interval(CI):1.55–1.76),1.59%(95%CI:1.50–1.69),and 1.27%(95%CI:1.17–1.36)respectively.Each 1%increase in relative humidity was associated with a 0.18%(95%CI:0.15–0.20)increase in visits.Mean pressure was negatively associated with outpatient visits,the outpatient visits decreased by 0.91%(95%CI:−1.71 to−0.11)for every 1 kPa increased in mean pressure.Conclusion:The change of meteorological factors will lead to the increase of outpatient visits in rabies exposure treatment clinic.展开更多
Objective:To understand the attitudes and perceptions of traditional Chinese medicine(TCM)practitioners in Beijing TCM hospitals regarding the use of Ephedra sinica Stapf(E.sinica,Ma Huang).Methods:A two-stage cross-s...Objective:To understand the attitudes and perceptions of traditional Chinese medicine(TCM)practitioners in Beijing TCM hospitals regarding the use of Ephedra sinica Stapf(E.sinica,Ma Huang).Methods:A two-stage cross-sectional study was conducted using a questionnaire survey of TCM practi-tioners in Beijing TCM hospitals between April 2023 and March 2024.The questionnaire included de-mographic information,the clinical background of TCM practitioners,and the clinical application of E.sinica.Logistic regression analysis was used to analyze the relevant influencing factors when using E.sinica.Results:Of the 465 questionnaires collected,441 were valid.Among these,84.81%(374/441)reported having used E.sinica in clinical practice at least once.The commonly used doses of E.sinicadexcluding the pediatric departmentdwere 10 g for high doses,6 g for medium,and 3 g for low.The three most frequently used formulas for E.sinica included Maxing Shigan decoction,Mahuang decoction,and Xiao Qing Long decoction.The most common TCM patterns treated with a high dose of E.sinica were wind-cold exterior pattern,wind-cold invading the lung,and wind and water combat with meridians con-gealed by cold.The top three Western medical diagnoses when using E.sinica for treatment were common cold,pneumonia,and upper respiratory tract infections.Nearly half of the respondents reported experiencing adverse reactions from the oral administration of E.sinica,with the most common being palpitations,insomnia,and restlessness.Starting with a low dose and gradually increasing it as appro-priate was identified as an effective approach.Conclusion:This study investigated the attitudes and perceptions of TCM practitioners in Beijing TCM hospitals regarding the doseeefficacyeadverse reaction relationship of E.sinica,providing a reference for the safe and effective clinical use of E.sinica.展开更多
Background: No other effects of atropine other than as an antagonist of muscarinic acetylcholine receptor (mAChR) have been found. Methods: In this study, human kidneyepithelial cells were treated with different physi...Background: No other effects of atropine other than as an antagonist of muscarinic acetylcholine receptor (mAChR) have been found. Methods: In this study, human kidneyepithelial cells were treated with different physiological regulators. Results: Subsequently, it was found that atropine could significantly induce autophagy as demonstrated by the appearance of autophagosome-like double- or single-membrane vesicles in the cytoplasm ofhost cells and the number of GFP-LC3 dots. In addition, increased conversion of the autophagy marker protein LC3-I and LC3-II and increased p62/SQSTM1 indicatedincomplete autophagy. In addition, atropine induced autophagosome levels in a dose-dependent manner within a certain concentration range in human kidney epithelial cells. In atropine-treated mouse skeletal muscle cells containing nicotinic acetylcholinereceptors and rat cardiac muscle cells containing mAchR, atropine induced autophagy in mouse skeletal muscle cells but not in rat cardiac muscle cells. Furthermore, atropine did not induce autophagy in tissue cells containing mAchR in vivo but did in tissue cells not containing mAchR. Conclusion: This study expands the application and understanding of atropine’s action mechanism in the field of medicine.展开更多
AIM:To observe the hepatic injury induced by carbon dioxide pneumoperitoneum(CDP) in rabbits,compare the eects olow-and high-pressure pneumoperitoneum,and to determine the degree o hepatic injury induced by these two ...AIM:To observe the hepatic injury induced by carbon dioxide pneumoperitoneum(CDP) in rabbits,compare the eects olow-and high-pressure pneumoperitoneum,and to determine the degree o hepatic injury induced by these two clinically relevant CDP pressures.METHODS:Thirty healthy male New Zealand rabbits weighing 3.0 to 3.5 kg were randomly divided into three groups(n = 10 for each group) and subjected to the ollowing to CDP pressures:no gas control,10 mmHg,or 15 mmHg.Histological changes in liver tissues were observed with hematoxylin and eosin staining and transmission electron microscopy.Liver unction was evaluated using an automatic biochemical analyzer.Adenine nucleotide translocator(ANT) activity in liver tissue was detected with the atractyloside-inhibitor stop technique.Bax and Bcl-2 expression levels were detected bywestern blotting.RESULTS:Liver Functions in the 10 mmHg and 15 mmHg experimental groups were significantly disturbed compared with the control group.After CDP,the levels or alanine transaminase and aspartate transaminase were 77.3 ± 14.5 IU/L and 60.1 ± 11.4 IU/L,respectively,in the 10 mmHg experimental group and 165.1 ± 19.4 IU/L and 103.8 ± 12.3 IU/L,respectively,in the 15 mmHg experimental group,which were all higher than those of the control group(p < 0.05).There was no difference in pre-albumin concentration between the 10 mmHg experimental group and the control group,but the prealbumin level of the 15 mmHg experimental group was significantly lower than that of the control group(p < 0.05).No significant differences were observed in the levels of total bilirubin or albumin among the three groups.After 30 and 60 min of CDP,pH was reduced(p < 0.05) and fa CO2 was elevated(p < 0.05) in the 10 mmHg group compared with controls,and these changes were more pronounced in the 15 mmHg group.Hematoxylin and eosin staining showed no significant change in liver morphology,except for mild hyperemia in the two experimental groups.Transmission electron microscopy showed mild mitochondrial swelling in hepatocytes of the 10 mmHg group,and this was more pronounced in the 15 mmHg group.No significant difference in ANT levels was found between the control and 10 mmHg groups.However,ANT concentration was significantly lower in the 15 mmHg group compared with the control group.The expression of hepatic Bax was significantly increased in the two experimental groups compared with the controls,but there were no differences in Bcl-2 levels among the three groups.Twelve hours after CDP induction,the expression of hepatic Bax was more significant in the 15 mmHg group than in the 10 mmHg group.CONCLUSION:A CDP pressure of 15 mmHg caused more substantial hepatic injury,such as increased levels of acidosis,mitochondrial damage,and apoptosis;therefore,10 mmHg CDP is preferable for laparoscopic operations.展开更多
Based on previous research results, this paper investigated the influence of fracture morphology on mechanical properties and failure modes of rock mass with two diagonal intersected fractures. This study carried out ...Based on previous research results, this paper investigated the influence of fracture morphology on mechanical properties and failure modes of rock mass with two diagonal intersected fractures. This study carried out a series of triaxial compression tests on rock-like specimens with two crossed fractures under negative temperature, concluded the following conclusions. The strength and failure modes of rock mass are significantly influenced by the dips of two crossed fractures. The strength of rock mass with two frac- tures cannot simply be estimated using the method that was developed for the rock mass with a single fracture. When the intersecting angle is less than 30~, the failure plane initiates at the tip of ＂artificial rup- tures＂ and extends to the upper and lower ends of the specimen. In case of a higher dip and intersecting angle ranging from 30° to 60°, the failure plane propagates along one of these two fractures. The mechan- lca! parameters of rock mass are not only related to the trace length, but also depend on the trace !ength ratio. One could roughly calculate the strength parameters using the approximation proposed in.this paper..For the rock mass with a trace length ratio 〈0.3 （short trace length/long trace length）, the failure mode is dependent on the fracture with a longer trace length. When the trace length becomes significant and the trace length ratio approximates to 1, the failure plane propagates along two fractures, where an X-shaped.failure pattern is presented： For the rock mass with moderate frac!ures and a trace length ratio of approxlmately 1, the failure mode Is.Independent on fractures, which is simllar to .the damage pattern of intact rock. The strength, and elastic .modulus of rock mass decrease with the increase of spacing between fractures, whl!e Polsson＇s ratio is Independent on the spacing. The failure mode can be deter- mined by the area. of triangle created by two fractures. Damage occurs at the smaller triangle area first, and propagates with the two sides of the larger triangle.展开更多
The ultrasonic (US) wave detection and an acoustic emission (AE) linear location system are proposed, which employ fiber Bragg gratings (FBGs) as US wave sensors. In the theoretical analysis, the FBG sensor response t...The ultrasonic (US) wave detection and an acoustic emission (AE) linear location system are proposed, which employ fiber Bragg gratings (FBGs) as US wave sensors. In the theoretical analysis, the FBG sensor response to longitudinal US wave is investigated. The result indicates that the FBG wavelength can be modulated as static case when the grating length is much shorter than US wavelength. The experimental results of standard sinusoidal and spindle wave test agree well with the generated signal. Further research using two FBGs for realizing linear location is also achieved. The maximum linear location error is obtained as less than 5 mm. FBG-based US wave sensor and AE linear location provide useful tools for specific requirements.展开更多
The exploitation of electromagnetic wave absorption(EMA) materials has attracted ever-increasing attention,not only because electromagnetic wave(EMW) originated from overuse of electronic products has threatened human...The exploitation of electromagnetic wave absorption(EMA) materials has attracted ever-increasing attention,not only because electromagnetic wave(EMW) originated from overuse of electronic products has threatened human' health seriously,but also because EMA materials can effectively protect radar stealth from being detected.However,it is still a challenge to obtain broadband and efficient EMA materials to satisfy practical applications.In this work,we developed a series of hierarchical CoFe alloy/porous carbon@carbon nanotubes(CoFe/PC@CNTs) nanocomposites through revising the proportion of Fe^(2+) in the metal-organic frameworks(MOFs)(CoFe-ZIF) precursor and one-step simple pyrolysis process.The cross deposition between CoFe alloy,carbon nanotubes(CNTs),and porous carbon(PC) formed a double conductive network,favoring for achieving excellent EMA property.Surprisingly,when the filler mass ratio is only 10 wt%,the optimized CoFe/PC@CNTs nanocomposites display the best EMA capability,whose minimum reflection loss(RL_(min)) value is-68.94 dB at 13.69 GHz and the effective absorption band(EAB,<-10 dB) reaches up 9.14 GHz with a matching thickness of 2.63 mm.In addition,the largest EAB can achieve up to 11 GHz(3.35-14.35 GHz) during all matching thicknesses.The splendid EMA performance benefits the favorable dielectric loss provided by the double conductive network,the good magnetic loss benefited from the evenly distributed CoFe alloy,the excellent impedance matching,rich transmission paths,and multiple polarization.Therefore,such EMA materials with super broadband absorbing provide desirable candidates for lightweight and high-efficient microwave absorbers.展开更多
A hyperbolic function is introduced to reflect the attenuation effect of one firm＇s default to its partner. If two firms are competitors （copartners）, the default intensity of one firm will decrease （increase） ab...A hyperbolic function is introduced to reflect the attenuation effect of one firm＇s default to its partner. If two firms are competitors （copartners）, the default intensity of one firm will decrease （increase） abruptly when the other firm defaults. As time goes on, the impact will decrease gradually until extinct. In this model, the joint distribution and marginal distributions of default times are derived by employing the change of measure, and the fair swap premium of a credit default swap （CDS） can be valued.展开更多
CF3I is a potential SF6 alternative gas.In order to study the insulation properties and synergistic effects of CF3I/N2 and CF3I/CO2 gas mixtures,two-term approximate Boltzmann equations were used to obtain the ionizat...CF3I is a potential SF6 alternative gas.In order to study the insulation properties and synergistic effects of CF3I/N2 and CF3I/CO2 gas mixtures,two-term approximate Boltzmann equations were used to obtain the ionization coefficient α,attachment coefficient η and the critical equivalent electrical field strength（E/N）（cr）.The results show that the（E/N）（cr）of CF3I gas at 300 K is 1.2 times that of SF6 gas,and CF3I/N2 and CF3I/CO2 gas mixtures both have synergistic effect occurred.The synergistic effect coefficient of CF3I/CO2 gas mixture was higher than that of CF3I/N2 gas mixture.But the（E/N）（cr）of CF3I/N2 is higher than that of CF3I/CO2 under the same conditions.When the content of CF3I exceeds 20%,the （E/N）（cr） of CF3I/N2 and CF3I/CO2 gas mixture increase linearly with the increasing of CF3I gas content.The breakdown voltage of CF3I/N2 gas mixture is also higher than that of CF3I/CO2 gas mixture in slightly non-uniform electrical field under power frequency voltage,but the synergistic effect coefficients of the two gas mixtures are basically the same.展开更多
Large quantities of data are accumulated in process planning for body in white （BIW）. To acquire thepotential and valuable process knowledge from these data, the rough set theory and association rule technique arein...Large quantities of data are accumulated in process planning for body in white （BIW）. To acquire thepotential and valuable process knowledge from these data, the rough set theory and association rule technique areintegrated to discover the useful correlations between the welding type and process requirements. The correlationscan guide us to select the welding type according to the given process requirements. During data mining, everyprocess requirement is regarded as an attribute. First, the decision table for the welding type is constructed. Sec-ond, rough set theory is employed to remove redundant attributes. A simplified decision table is constructed.Third, association rule is used to extract the useful rules. Finally, an illustrative example indicates this methodol-ogy can extract useful rules for the selection of welding type.展开更多
The steel reinforced plastic pipe is a kind of green environmental protection pipelines with double-sides corrosionresisting and better withstanding to medium working pressure. The structure and technical process of t...The steel reinforced plastic pipe is a kind of green environmental protection pipelines with double-sides corrosionresisting and better withstanding to medium working pressure. The structure and technical process of this pipe are described briefly in this paper, and the finite element analysis has been done for the sake of understanding the distributions of stress and displacement inside this pipe under hydrostatic pressure. The analysis results are very important for safety application of the steel reinforced plastic pipe.展开更多
Identification of the aging condition and the failure probability of oil-paper insulation in transformer is important for improving the reliability of electric power transmission system and applying life cycle cost (L...Identification of the aging condition and the failure probability of oil-paper insulation in transformer is important for improving the reliability of electric power transmission system and applying life cycle cost (LCC) management to electrical equipment. Based on data obtained in a series of multi-accelerated-aging experiments, two approaches for calculating failure probability of oil-paper insulation were compared in aspects of degree of polymerization (DP) and condition ranking. In the experiments, mineral oil and cellulose paper are sub- jected to electrical and thermal stresses, and several parameters, including dissolved gases’ volume fraction, furfural content, moisture content, and degree of polymerization, are measured after the aging process. Results show that weight of carbon oxide, which has a close relationship with cellulose paper degradation, is much higher in DP model than in condition ranking model. Moreover, it is concluded that DP model is more practically accurate than condition ranking model, because aging of cellulose paper rather than mineral oil is the key and critical factor of oil-paper insulation aging.展开更多
Si nanoparticles are synthesized at a high rate(400-500 mg/h) using the perpendicular pulsed laser ablation(PPLA) on the silicon target at room temperature in Ar atmosphere.The PPLA method can also be used to obtain S...Si nanoparticles are synthesized at a high rate(400-500 mg/h) using the perpendicular pulsed laser ablation(PPLA) on the silicon target at room temperature in Ar atmosphere.The PPLA method can also be used to obtain Si nanocrystal films with large areas on the glass substrate.These particles are etched with a mixture of hydrofluoric acid(HF) and nitric acid(HNO3) to reduce their sizes and the surfaces of these particles are passivated by the high-pressure water vapor annealing(HWA).After treating the particles exhibit blue emission(with maximum photoluminescence(PL) intensity at 404 nm) at room temperature.展开更多
As a new class of forward error correcting encoding algorithm,Luby Transform codes are suitable for the erasure channel environment based on the packet communication.The encoding,decoding algorithms and the implementa...As a new class of forward error correcting encoding algorithm,Luby Transform codes are suitable for the erasure channel environment based on the packet communication.The encoding,decoding algorithms and the implementation of LT codes are summarized in the paper.Meanwhile simulations of the ideal soliton distribution and robust soliton distribution are conducted to evaluate the performance of LT codes in terms of successful decoding probability,mean degree and decoding time over the erasure channel.The parameter optimization rules of LT codes are deeply discussed and proposed in the paper.The research results are of great practical importance for improving the real time performance in the erasure correction applications.展开更多
Introducing voids into AlN layer at a certain height using a simple method is meaningful but challenging.In this work,the AlN/sapphire template with AlN interlayer structure was designed and grown by metal-organic che...Introducing voids into AlN layer at a certain height using a simple method is meaningful but challenging.In this work,the AlN/sapphire template with AlN interlayer structure was designed and grown by metal-organic chemical vapor deposition.Then,the AlN template was annealed at 1700℃for an hour to introduce the voids.It was found that voids were formed in the AlN layer after high-temperature annealing and they were mainly distributed around the AlN interlayer.Meanwhile,the dislocation density of the AlN template decreased from 5.26×10^(9)cm^(-2)to 5.10×10^(8)cm^(-2).This work provides a possible method to introduce voids into AlN layer at a designated height,which will benefit the design of AlN-based devices.展开更多
The application of bio-inspired computational techniques to the field of condition monitoring is addressed. First, the bio-inspired computational techniques are briefly addressed; the advantages and disadvantages of t...The application of bio-inspired computational techniques to the field of condition monitoring is addressed. First, the bio-inspired computational techniques are briefly addressed; the advantages and disadvantages of these computational methods are made clear. Then, the roles of condition monitoring in the predictive maintenance and failures prediction and the development trends of condition monitoring are discussed. Finally, a case study on the condition monitoring of grinding machine is described, which shows the application of bio-inspired computational technique to a practical condition monitoring system.展开更多
Objective: To reveal the mechanism and effect of SU5416 in the treatment of mouse Lewis cancer in vivo. Methods: Lewis cell was transplanted into groin of C57/B6 mouse by subcutaneous injection, then SU5416 was admini...Objective: To reveal the mechanism and effect of SU5416 in the treatment of mouse Lewis cancer in vivo. Methods: Lewis cell was transplanted into groin of C57/B6 mouse by subcutaneous injection, then SU5416 was administrated intraperitoneally to investigate the impact of SU5416 on tumor angiogenesis and growth in vivo. 32 mice were treated with SU5416 at two different doses every day until the end-point. As a control, 8 mice received no treatment and 8 mice were treated with vehicle (DMSO) only after implantation. Results: Median survival in the treated group was statistically longer compared to that in the control groups (P < 0.05) and no significant systemic adverse was observed. Histological analysis of the treated tumors showed an increase in necroses and reduced in angiogenesis compared to the control tumors. Furthermore, the percent of apoptotic cells increased in the treated tumors by FCM, the expressions of VEGF and KDR had no change after SU5416 administration by western blot. Conclusion: SU5416 may be useful therapeutics drug that specifically inhibits the enzymatic activity of KDR kinase and could down regulate the tumor angiogenesis.展开更多
Nano-crystalline pre-alloyed powders of W-Ni-Fe were fabricated by high energy ball milling mechanical alloying (MA) technique. The change of appearances and the crystallite sizes of powders before and after high ener...Nano-crystalline pre-alloyed powders of W-Ni-Fe were fabricated by high energy ball milling mechanical alloying (MA) technique. The change of appearances and the crystallite sizes of powders before and after high energy ball milling were investigated by XRD, TOPAS P software, SEM and EDS. The results show that the nano-crystalline pre-alloyed powders can be fabricated by 5 h high energy ball milling. During the MA process, the diffusion of W, Ni and Fe happens in the process of repeated welding and fracturing. As a result, nano-crystalline supersaturated solid solutions are formed. The crystallite sizes won't be refined after 10 h ball milling. The crystallite sizes of different compositions are almost the same under the same MA condition. Due to the toughening mechanism of rare earth element, the powders of 90W-4Ni-2Fe-3.8Mo-0.2RE alloy are seriously agglomerated after ball milling compared with the other alloys. It can be concluded that the optimal sintering temperature of 90W-4Ni-2Fe-3.8Mo-0.2RE pre-alloyed powders after 15 h mechanical alloying is 1 300-1 350 ℃.展开更多
The application of a novel Automatic Dynamic Simulator of Fouling (ADSF) to evaluate the effectiveness of ion-rod water treater is reported.The effects of some parameters of the water treater were studied with an ADSF...The application of a novel Automatic Dynamic Simulator of Fouling (ADSF) to evaluate the effectiveness of ion-rod water treater is reported.The effects of some parameters of the water treater were studied with an ADSF made according to patented technology, and orthogonal experimental design was adopted with the use of artificial hard water.Experimental results validated that the ion-rod water treater could mitigate fouling,and the anti-fouling efficiency varies with the test conditions.The anti-fouling efficiency of treater increased with the increase of flow velocity in the range of 0.8—1.2 m·s -1 and output voltage in the range of 7500—15000 V.The efficiency weat up initially, and then went down with the increase in hardness.The rough surface of ion-rod was superior to the smooth one.The order of influence on treater performance with respect to these factors was as follows: water hardness, roughness of surface, flow velocity and output voltage.The research also provided a guide to improving the performance of ion-rod water treater.展开更多
文摘Pedestrian detection has been a hot spot in computer vision over the past decades due to the wide spectrum of promising applications,and the major challenge is false positives that occur during pedestrian detection.The emergence of various Convolutional Neural Network-based detection strategies substantially enhances pedestrian detection accuracy but still does not solve this problem well.This paper deeply analyzes the detection framework of the two-stage CNN detection methods and finds out false positives in detection results are due to its training strategy misclassifying some false proposals,thus weakening the classification capability of the following subnetwork and hardly suppressing false ones.To solve this problem,this paper proposes a pedestrian-sensitive training algorithm to help two-stage CNN detection methods effectively learn to distinguish the pedestrian and non-pedestrian samples and suppress the false positives in the final detection results.The core of the proposed algorithm is to redesign the training proposal generating scheme for the two-stage CNN detection methods,which can avoid a certain number of false ones that mislead its training process.With the help of the proposed algorithm,the detection accuracy of the MetroNext,a smaller and more accurate metro passenger detector,is further improved,which further decreases false ones in its metro passenger detection results.Based on various challenging benchmark datasets,experiment results have demonstrated that the feasibility of the proposed algorithm is effective in improving pedestrian detection accuracy by removing false positives.Compared with the existing state-of-the-art detection networks,PSTNet demonstrates better overall prediction performance in accuracy,total number of parameters,and inference time;thus,it can become a practical solution for hunting pedestrians on various hardware platforms,especially for mobile and edge devices.
基金supported by Chinese Association of Preventive Medicine-Vaccine and Immunization Youth Talent Support Project(CPMAQT-YM0314)Shandong medical and health science and technology development plan project(202012050267)Shandong Center for Disease Control and Prevention-Youth Innovation Fund Project(QC-202301).
文摘Background:This study investigated the relationship between meteorological factors and daily outpatient visits to rabies post-exposure prophylaxis clinics to inform animal injury prevention strategies.Methods:Daily outpatient visit data from rabies post-exposure prophylaxis clinics in Jinan and corresponding meteorological data were collected from January 1,2020,to December 31,2022.A generalized additive model was used to quantitatively assess the relationship between these factors.A total of 202,010 patients visited these clinics during this period.Results:Daily mean,maximum,and minimum temperatures,and relative humidity were positively associated with outpatient visits.A 1°C increase in mean,maximum,and minimum temperatures corresponded to increases in daily visits of 1.65%(95%Confidence Interval(CI):1.55–1.76),1.59%(95%CI:1.50–1.69),and 1.27%(95%CI:1.17–1.36)respectively.Each 1%increase in relative humidity was associated with a 0.18%(95%CI:0.15–0.20)increase in visits.Mean pressure was negatively associated with outpatient visits,the outpatient visits decreased by 0.91%(95%CI:−1.71 to−0.11)for every 1 kPa increased in mean pressure.Conclusion:The change of meteorological factors will lead to the increase of outpatient visits in rabies exposure treatment clinic.
基金supported by the Scientific Project of the China Medical Association of Minorities(2023ZY-182-07)and the horizontal project of Beijing University of Chinese Medicine.
文摘Objective:To understand the attitudes and perceptions of traditional Chinese medicine(TCM)practitioners in Beijing TCM hospitals regarding the use of Ephedra sinica Stapf(E.sinica,Ma Huang).Methods:A two-stage cross-sectional study was conducted using a questionnaire survey of TCM practi-tioners in Beijing TCM hospitals between April 2023 and March 2024.The questionnaire included de-mographic information,the clinical background of TCM practitioners,and the clinical application of E.sinica.Logistic regression analysis was used to analyze the relevant influencing factors when using E.sinica.Results:Of the 465 questionnaires collected,441 were valid.Among these,84.81%(374/441)reported having used E.sinica in clinical practice at least once.The commonly used doses of E.sinicadexcluding the pediatric departmentdwere 10 g for high doses,6 g for medium,and 3 g for low.The three most frequently used formulas for E.sinica included Maxing Shigan decoction,Mahuang decoction,and Xiao Qing Long decoction.The most common TCM patterns treated with a high dose of E.sinica were wind-cold exterior pattern,wind-cold invading the lung,and wind and water combat with meridians con-gealed by cold.The top three Western medical diagnoses when using E.sinica for treatment were common cold,pneumonia,and upper respiratory tract infections.Nearly half of the respondents reported experiencing adverse reactions from the oral administration of E.sinica,with the most common being palpitations,insomnia,and restlessness.Starting with a low dose and gradually increasing it as appro-priate was identified as an effective approach.Conclusion:This study investigated the attitudes and perceptions of TCM practitioners in Beijing TCM hospitals regarding the doseeefficacyeadverse reaction relationship of E.sinica,providing a reference for the safe and effective clinical use of E.sinica.
基金National Natural Science Foundation of China(32202800)Natural Science Foundation of Heilongjiang Province(LH2022C104)+1 种基金Heilongjiang Province Education Department Fundamental Scientifc Research Funds(145109516)Qiqihar University Graduate Innovative Research Project(YJSCX2022016).
文摘Background: No other effects of atropine other than as an antagonist of muscarinic acetylcholine receptor (mAChR) have been found. Methods: In this study, human kidneyepithelial cells were treated with different physiological regulators. Results: Subsequently, it was found that atropine could significantly induce autophagy as demonstrated by the appearance of autophagosome-like double- or single-membrane vesicles in the cytoplasm ofhost cells and the number of GFP-LC3 dots. In addition, increased conversion of the autophagy marker protein LC3-I and LC3-II and increased p62/SQSTM1 indicatedincomplete autophagy. In addition, atropine induced autophagosome levels in a dose-dependent manner within a certain concentration range in human kidney epithelial cells. In atropine-treated mouse skeletal muscle cells containing nicotinic acetylcholinereceptors and rat cardiac muscle cells containing mAchR, atropine induced autophagy in mouse skeletal muscle cells but not in rat cardiac muscle cells. Furthermore, atropine did not induce autophagy in tissue cells containing mAchR in vivo but did in tissue cells not containing mAchR. Conclusion: This study expands the application and understanding of atropine’s action mechanism in the field of medicine.
基金Supported by The Eleventh-five Medical Science Fund of Chengdu Military Command Area,No. MB07011China Post doctoral Science Foundation,No. 20100471764
文摘AIM:To observe the hepatic injury induced by carbon dioxide pneumoperitoneum(CDP) in rabbits,compare the eects olow-and high-pressure pneumoperitoneum,and to determine the degree o hepatic injury induced by these two clinically relevant CDP pressures.METHODS:Thirty healthy male New Zealand rabbits weighing 3.0 to 3.5 kg were randomly divided into three groups(n = 10 for each group) and subjected to the ollowing to CDP pressures:no gas control,10 mmHg,or 15 mmHg.Histological changes in liver tissues were observed with hematoxylin and eosin staining and transmission electron microscopy.Liver unction was evaluated using an automatic biochemical analyzer.Adenine nucleotide translocator(ANT) activity in liver tissue was detected with the atractyloside-inhibitor stop technique.Bax and Bcl-2 expression levels were detected bywestern blotting.RESULTS:Liver Functions in the 10 mmHg and 15 mmHg experimental groups were significantly disturbed compared with the control group.After CDP,the levels or alanine transaminase and aspartate transaminase were 77.3 ± 14.5 IU/L and 60.1 ± 11.4 IU/L,respectively,in the 10 mmHg experimental group and 165.1 ± 19.4 IU/L and 103.8 ± 12.3 IU/L,respectively,in the 15 mmHg experimental group,which were all higher than those of the control group(p < 0.05).There was no difference in pre-albumin concentration between the 10 mmHg experimental group and the control group,but the prealbumin level of the 15 mmHg experimental group was significantly lower than that of the control group(p < 0.05).No significant differences were observed in the levels of total bilirubin or albumin among the three groups.After 30 and 60 min of CDP,pH was reduced(p < 0.05) and fa CO2 was elevated(p < 0.05) in the 10 mmHg group compared with controls,and these changes were more pronounced in the 15 mmHg group.Hematoxylin and eosin staining showed no significant change in liver morphology,except for mild hyperemia in the two experimental groups.Transmission electron microscopy showed mild mitochondrial swelling in hepatocytes of the 10 mmHg group,and this was more pronounced in the 15 mmHg group.No significant difference in ANT levels was found between the control and 10 mmHg groups.However,ANT concentration was significantly lower in the 15 mmHg group compared with the control group.The expression of hepatic Bax was significantly increased in the two experimental groups compared with the controls,but there were no differences in Bcl-2 levels among the three groups.Twelve hours after CDP induction,the expression of hepatic Bax was more significant in the 15 mmHg group than in the 10 mmHg group.CONCLUSION:A CDP pressure of 15 mmHg caused more substantial hepatic injury,such as increased levels of acidosis,mitochondrial damage,and apoptosis;therefore,10 mmHg CDP is preferable for laparoscopic operations.
文摘Based on previous research results, this paper investigated the influence of fracture morphology on mechanical properties and failure modes of rock mass with two diagonal intersected fractures. This study carried out a series of triaxial compression tests on rock-like specimens with two crossed fractures under negative temperature, concluded the following conclusions. The strength and failure modes of rock mass are significantly influenced by the dips of two crossed fractures. The strength of rock mass with two frac- tures cannot simply be estimated using the method that was developed for the rock mass with a single fracture. When the intersecting angle is less than 30~, the failure plane initiates at the tip of ＂artificial rup- tures＂ and extends to the upper and lower ends of the specimen. In case of a higher dip and intersecting angle ranging from 30° to 60°, the failure plane propagates along one of these two fractures. The mechan- lca! parameters of rock mass are not only related to the trace length, but also depend on the trace !ength ratio. One could roughly calculate the strength parameters using the approximation proposed in.this paper..For the rock mass with a trace length ratio 〈0.3 （short trace length/long trace length）, the failure mode is dependent on the fracture with a longer trace length. When the trace length becomes significant and the trace length ratio approximates to 1, the failure plane propagates along two fractures, where an X-shaped.failure pattern is presented： For the rock mass with moderate frac!ures and a trace length ratio of approxlmately 1, the failure mode Is.Independent on fractures, which is simllar to .the damage pattern of intact rock. The strength, and elastic .modulus of rock mass decrease with the increase of spacing between fractures, whl!e Polsson＇s ratio is Independent on the spacing. The failure mode can be deter- mined by the area. of triangle created by two fractures. Damage occurs at the smaller triangle area first, and propagates with the two sides of the larger triangle.
基金supported by the National Natural Science Foundation of China (No. 61074163)the Natural Science Foundation of Shandong Province (No.ZR2011FQ025)the Independent Innovation Fund of Shandong University (No.2010GN066)
文摘The ultrasonic (US) wave detection and an acoustic emission (AE) linear location system are proposed, which employ fiber Bragg gratings (FBGs) as US wave sensors. In the theoretical analysis, the FBG sensor response to longitudinal US wave is investigated. The result indicates that the FBG wavelength can be modulated as static case when the grating length is much shorter than US wavelength. The experimental results of standard sinusoidal and spindle wave test agree well with the generated signal. Further research using two FBGs for realizing linear location is also achieved. The maximum linear location error is obtained as less than 5 mm. FBG-based US wave sensor and AE linear location provide useful tools for specific requirements.
基金financially supported by the National Natural Science Foundation of China (NSFC,Nos.51978354,52002201,52008223)the major program of Shandong province (No.GG201809170147)+3 种基金Outstanding Youth Foundation of Shandong province (No.ZR2020YQ43)Qingchuang Technology Project (No.2020KJG002)Natural Science Foundation of Shandong Province(No.ZR2020QE055)the fellowship support received from the Tai Shan Scholar Programme。
文摘The exploitation of electromagnetic wave absorption(EMA) materials has attracted ever-increasing attention,not only because electromagnetic wave(EMW) originated from overuse of electronic products has threatened human' health seriously,but also because EMA materials can effectively protect radar stealth from being detected.However,it is still a challenge to obtain broadband and efficient EMA materials to satisfy practical applications.In this work,we developed a series of hierarchical CoFe alloy/porous carbon@carbon nanotubes(CoFe/PC@CNTs) nanocomposites through revising the proportion of Fe^(2+) in the metal-organic frameworks(MOFs)(CoFe-ZIF) precursor and one-step simple pyrolysis process.The cross deposition between CoFe alloy,carbon nanotubes(CNTs),and porous carbon(PC) formed a double conductive network,favoring for achieving excellent EMA property.Surprisingly,when the filler mass ratio is only 10 wt%,the optimized CoFe/PC@CNTs nanocomposites display the best EMA capability,whose minimum reflection loss(RL_(min)) value is-68.94 dB at 13.69 GHz and the effective absorption band(EAB,<-10 dB) reaches up 9.14 GHz with a matching thickness of 2.63 mm.In addition,the largest EAB can achieve up to 11 GHz(3.35-14.35 GHz) during all matching thicknesses.The splendid EMA performance benefits the favorable dielectric loss provided by the double conductive network,the good magnetic loss benefited from the evenly distributed CoFe alloy,the excellent impedance matching,rich transmission paths,and multiple polarization.Therefore,such EMA materials with super broadband absorbing provide desirable candidates for lightweight and high-efficient microwave absorbers.
基金the National Basic Research Program of China(973 Program)(No.2007CB814903)the National Natural Science Foundation of China(No.70671069)
文摘A hyperbolic function is introduced to reflect the attenuation effect of one firm＇s default to its partner. If two firms are competitors （copartners）, the default intensity of one firm will decrease （increase） abruptly when the other firm defaults. As time goes on, the impact will decrease gradually until extinct. In this model, the joint distribution and marginal distributions of default times are derived by employing the change of measure, and the fair swap premium of a credit default swap （CDS） can be valued.
基金supported by National Natural Science Foundation of China (Grant No.51337006)China Postdoctoral Science Foundation (2016M602728)the Science and Technology Project of SGCC ‘Research on SF_6 Alternative Gas for Insulation and Arc Quenching Application’
文摘CF3I is a potential SF6 alternative gas.In order to study the insulation properties and synergistic effects of CF3I/N2 and CF3I/CO2 gas mixtures,two-term approximate Boltzmann equations were used to obtain the ionization coefficient α,attachment coefficient η and the critical equivalent electrical field strength（E/N）（cr）.The results show that the（E/N）（cr）of CF3I gas at 300 K is 1.2 times that of SF6 gas,and CF3I/N2 and CF3I/CO2 gas mixtures both have synergistic effect occurred.The synergistic effect coefficient of CF3I/CO2 gas mixture was higher than that of CF3I/N2 gas mixture.But the（E/N）（cr）of CF3I/N2 is higher than that of CF3I/CO2 under the same conditions.When the content of CF3I exceeds 20%,the （E/N）（cr） of CF3I/N2 and CF3I/CO2 gas mixture increase linearly with the increasing of CF3I gas content.The breakdown voltage of CF3I/N2 gas mixture is also higher than that of CF3I/CO2 gas mixture in slightly non-uniform electrical field under power frequency voltage,but the synergistic effect coefficients of the two gas mixtures are basically the same.
基金support by Xinjiang special major project of science and technology [201130110]Xinjiang University doctor initial foundation [BS130119]
文摘Large quantities of data are accumulated in process planning for body in white （BIW）. To acquire thepotential and valuable process knowledge from these data, the rough set theory and association rule technique areintegrated to discover the useful correlations between the welding type and process requirements. The correlationscan guide us to select the welding type according to the given process requirements. During data mining, everyprocess requirement is regarded as an attribute. First, the decision table for the welding type is constructed. Sec-ond, rough set theory is employed to remove redundant attributes. A simplified decision table is constructed.Third, association rule is used to extract the useful rules. Finally, an illustrative example indicates this methodol-ogy can extract useful rules for the selection of welding type.
文摘The steel reinforced plastic pipe is a kind of green environmental protection pipelines with double-sides corrosionresisting and better withstanding to medium working pressure. The structure and technical process of this pipe are described briefly in this paper, and the finite element analysis has been done for the sake of understanding the distributions of stress and displacement inside this pipe under hydrostatic pressure. The analysis results are very important for safety application of the steel reinforced plastic pipe.
基金Project supported by National Basic Research Program of China (973 Program) (2011CB 209404)
文摘Identification of the aging condition and the failure probability of oil-paper insulation in transformer is important for improving the reliability of electric power transmission system and applying life cycle cost (LCC) management to electrical equipment. Based on data obtained in a series of multi-accelerated-aging experiments, two approaches for calculating failure probability of oil-paper insulation were compared in aspects of degree of polymerization (DP) and condition ranking. In the experiments, mineral oil and cellulose paper are sub- jected to electrical and thermal stresses, and several parameters, including dissolved gases’ volume fraction, furfural content, moisture content, and degree of polymerization, are measured after the aging process. Results show that weight of carbon oxide, which has a close relationship with cellulose paper degradation, is much higher in DP model than in condition ranking model. Moreover, it is concluded that DP model is more practically accurate than condition ranking model, because aging of cellulose paper rather than mineral oil is the key and critical factor of oil-paper insulation aging.
基金supported by the National Natural Science Foundation of China (Nos.50872024 and 50903028)Heilongjiang Science and Technology Foundation (No.GB08A401-2)+2 种基金Foundation of Science and Technology Bureau of Heilongjiang (No.QC08C10)Harbin Youth Foundation (No.2005AFQXJ062)China Postdoctoral Science Foundation (No.20070410892)
文摘Si nanoparticles are synthesized at a high rate(400-500 mg/h) using the perpendicular pulsed laser ablation(PPLA) on the silicon target at room temperature in Ar atmosphere.The PPLA method can also be used to obtain Si nanocrystal films with large areas on the glass substrate.These particles are etched with a mixture of hydrofluoric acid(HF) and nitric acid(HNO3) to reduce their sizes and the surfaces of these particles are passivated by the high-pressure water vapor annealing(HWA).After treating the particles exhibit blue emission(with maximum photoluminescence(PL) intensity at 404 nm) at room temperature.
基金supported by Zhongguancun Haidian Science Park Postdoctoral Special Fund
文摘As a new class of forward error correcting encoding algorithm,Luby Transform codes are suitable for the erasure channel environment based on the packet communication.The encoding,decoding algorithms and the implementation of LT codes are summarized in the paper.Meanwhile simulations of the ideal soliton distribution and robust soliton distribution are conducted to evaluate the performance of LT codes in terms of successful decoding probability,mean degree and decoding time over the erasure channel.The parameter optimization rules of LT codes are deeply discussed and proposed in the paper.The research results are of great practical importance for improving the real time performance in the erasure correction applications.
基金the National Key Research and Development Program of China(Grant No.2017YFB0404100)the National Natural Science Foundation of China(Grant Nos.61827813,61974144,and 62004127)+2 种基金the Key Research Program of the Chinese Academy of Sciences(Grant No.XDPB22)the Key-Area Research and Development Program of Guangdong Province,China(Grant Nos.2020B010169001 and 2020B010174003)the Science and Technology Foundation of Shenzhen(Grant No.JSGG20191129114216474)。
文摘Introducing voids into AlN layer at a certain height using a simple method is meaningful but challenging.In this work,the AlN/sapphire template with AlN interlayer structure was designed and grown by metal-organic chemical vapor deposition.Then,the AlN template was annealed at 1700℃for an hour to introduce the voids.It was found that voids were formed in the AlN layer after high-temperature annealing and they were mainly distributed around the AlN interlayer.Meanwhile,the dislocation density of the AlN template decreased from 5.26×10^(9)cm^(-2)to 5.10×10^(8)cm^(-2).This work provides a possible method to introduce voids into AlN layer at a designated height,which will benefit the design of AlN-based devices.
基金supported by the National Natural Science Foundation of China ( No. 61025019No. 90820016)+1 种基金Program for New Century Excellent Talents in University ( No. NECT-07-0735)Natural Science Foundation of Hebei ( No. F2009001638)
文摘The application of bio-inspired computational techniques to the field of condition monitoring is addressed. First, the bio-inspired computational techniques are briefly addressed; the advantages and disadvantages of these computational methods are made clear. Then, the roles of condition monitoring in the predictive maintenance and failures prediction and the development trends of condition monitoring are discussed. Finally, a case study on the condition monitoring of grinding machine is described, which shows the application of bio-inspired computational technique to a practical condition monitoring system.
基金a grant from the National Key Project of Scientific and Technical Supporting Programs funded by Ministry of Science & Technology of China (No. 2006BAI02A05).
文摘Objective: To reveal the mechanism and effect of SU5416 in the treatment of mouse Lewis cancer in vivo. Methods: Lewis cell was transplanted into groin of C57/B6 mouse by subcutaneous injection, then SU5416 was administrated intraperitoneally to investigate the impact of SU5416 on tumor angiogenesis and growth in vivo. 32 mice were treated with SU5416 at two different doses every day until the end-point. As a control, 8 mice received no treatment and 8 mice were treated with vehicle (DMSO) only after implantation. Results: Median survival in the treated group was statistically longer compared to that in the control groups (P < 0.05) and no significant systemic adverse was observed. Histological analysis of the treated tumors showed an increase in necroses and reduced in angiogenesis compared to the control tumors. Furthermore, the percent of apoptotic cells increased in the treated tumors by FCM, the expressions of VEGF and KDR had no change after SU5416 administration by western blot. Conclusion: SU5416 may be useful therapeutics drug that specifically inhibits the enzymatic activity of KDR kinase and could down regulate the tumor angiogenesis.
基金Project(2006259) supported by the Education Science Foundation of Jiangxi Provincial Education DepartmentProject(2007gqc1562) supported by the Natural Science Foundation of Jiangxi Province, China
文摘Nano-crystalline pre-alloyed powders of W-Ni-Fe were fabricated by high energy ball milling mechanical alloying (MA) technique. The change of appearances and the crystallite sizes of powders before and after high energy ball milling were investigated by XRD, TOPAS P software, SEM and EDS. The results show that the nano-crystalline pre-alloyed powders can be fabricated by 5 h high energy ball milling. During the MA process, the diffusion of W, Ni and Fe happens in the process of repeated welding and fracturing. As a result, nano-crystalline supersaturated solid solutions are formed. The crystallite sizes won't be refined after 10 h ball milling. The crystallite sizes of different compositions are almost the same under the same MA condition. Due to the toughening mechanism of rare earth element, the powders of 90W-4Ni-2Fe-3.8Mo-0.2RE alloy are seriously agglomerated after ball milling compared with the other alloys. It can be concluded that the optimal sintering temperature of 90W-4Ni-2Fe-3.8Mo-0.2RE pre-alloyed powders after 15 h mechanical alloying is 1 300-1 350 ℃.
基金supported by Jilin Distinguished YoungScholars Program (20040121).
文摘The application of a novel Automatic Dynamic Simulator of Fouling (ADSF) to evaluate the effectiveness of ion-rod water treater is reported.The effects of some parameters of the water treater were studied with an ADSF made according to patented technology, and orthogonal experimental design was adopted with the use of artificial hard water.Experimental results validated that the ion-rod water treater could mitigate fouling,and the anti-fouling efficiency varies with the test conditions.The anti-fouling efficiency of treater increased with the increase of flow velocity in the range of 0.8—1.2 m·s -1 and output voltage in the range of 7500—15000 V.The efficiency weat up initially, and then went down with the increase in hardness.The rough surface of ion-rod was superior to the smooth one.The order of influence on treater performance with respect to these factors was as follows: water hardness, roughness of surface, flow velocity and output voltage.The research also provided a guide to improving the performance of ion-rod water treater.
