Oxidative stress has long been implicated as a driving force in neurodegenerative disease,with studies of human brain tissue and animal models revealing its important role.Parkinson’s disease(PD),in particular,highli...Oxidative stress has long been implicated as a driving force in neurodegenerative disease,with studies of human brain tissue and animal models revealing its important role.Parkinson’s disease(PD),in particular,highlights the selective vulnerability of neurons to the insults of reactive oxygen species.The motor symptoms of PD are caused by degeneration of dopamine neurons in the substantia nigra.These neurons experience increased oxidative stress due in part to highly active mitochondria that support their high bioenergetic demand and the generation of reactive oxygen species by dopamine metabolism(Watanabe et al.,2024).展开更多
This study demonstrates a novel integration of large language models,machine learning,and multicriteria decision-making to investigate self-moderation in small online communities,a topic under-explored compared to use...This study demonstrates a novel integration of large language models,machine learning,and multicriteria decision-making to investigate self-moderation in small online communities,a topic under-explored compared to user behavior and platform-driven moderation on social media.The proposed methodological framework(1)utilizes large language models for social media post analysis and categorization,(2)employs k-means clustering for content characterization,and(3)incorporates the TODIM(Tomada de Decisão Interativa Multicritério)method to determine moderation strategies based on expert judgments.In general,the fully integrated framework leverages the strengths of these intelligent systems in a more systematic evaluation of large-scale decision problems.When applied in social media moderation,this approach promotes nuanced and context-sensitive self-moderation by taking into account factors such as cultural background and geographic location.The application of this framework is demonstrated within Facebook groups.Eight distinct content clusters encompassing safety,harassment,diversity,and misinformation are identified.Analysis revealed a preference for content removal across all clusters,suggesting a cautious approach towards potentially harmful content.However,the framework also highlights the use of other moderation actions,like account suspension,depending on the content category.These findings contribute to the growing body of research on self-moderation and offer valuable insights for creating safer and more inclusive online spaces within smaller communities.展开更多
Metal halides are an important class of optoelectronic materials combining exceptional optical and electronic properties.An inherent advantage of metal halides is their solution synthesis and processability,which rend...Metal halides are an important class of optoelectronic materials combining exceptional optical and electronic properties.An inherent advantage of metal halides is their solution synthesis and processability,which render them as low-cost and environmentally friendly materials for a range of applications from photovoltaics and photodetection to solid-state lighting(SSL).In this study,we synthesized three previously unreported lead-free organic–inorganic hybrid copper halides:(OA)_(4)CuX_(5)(X=Br,I;OA^(+) =C_(8)H_(17)NH_(3)^(+) ,n-octylammonium cation)and(HA)_(2)CuI_(3)(HA^(+) =C_(6)H_(13)NH_(3)^(+) ,n-hexylammonium cation),all of which exhibit broadband emissions arising from self-trapped excitons(STEs).Among these compounds,(OA)_(4)CuI_(5) demonstrates tunable dual-band white-light emission with a high color rendering index value of 91 at room temperature.Temperature-dependent photoluminescence measurements and first-principles calculations reveal distinct behaviors between the two emission states in(OA)_(4)CuI_(5).These findings highlight the potential of copper halide compounds for optoelectronic applications,particularly in the development of environmentally friendly solid-state lighting technologies.展开更多
Based on the Smit-Suhl formula,we propose a universal approach for solving the magnon-magnon coupling problem in bilayer coupled systems(e.g.,antiferromagnets).This method requires only the energy expression,enabling ...Based on the Smit-Suhl formula,we propose a universal approach for solving the magnon-magnon coupling problem in bilayer coupled systems(e.g.,antiferromagnets).This method requires only the energy expression,enabling the automatic derivation of analytical expressions for the eigenmatrix elements via symbolic computation,eliminating the need for tedious manual calculations.Using this approach,we investigate the impact of magnetic hysteresis on magnon-magnon coupling in a system with interlayer Dzyaloshinskii-Moriya interaction(DMI).The magnetic hysteresis leads to an asymmetric magnetic field dependence of the resonance frequency and alters the number of degeneracy points between the pure optical and acoustic modes.Moreover,it can result in the coupling strength at the gap of the f–H phase diagram being nearly vanishing,contrary to the conventionally expected maximum.These results deepen the understanding of the effect of interlayer DMI on magnon–magnon coupling and the proposed universal method significantly streamlines the solving process of magnon–magnon coupling problems.展开更多
Green roofs have become a common method to increase water retention on-site in urban areas.However,the long-term water quality of runoff from green roofs is poorly understood.This study evaluated the water quality of ...Green roofs have become a common method to increase water retention on-site in urban areas.However,the long-term water quality of runoff from green roofs is poorly understood.This study evaluated the water quality of stormwater runoff from a regular(non-vegetated)roof,a green roof installed 6 months previously,and a green roof installed 6 years ago in Portland,Oregon.Samples of runoff were taken during every rain event for 10 months,and analyzed for total phosphorus(TP),phosphate(PO_(4)^(3-)),total nitrogen(TN),nitrate(NO_(3)^(-)),ammonia(NH_(3)),copper(Cu),and zinc(Zn).Runoff from the green roofs had higher concentrations of TP and PO_(4)^(3-)and lower concentrations of Zn compared to the regular roof.Average TP concentrations from the 6-year old roof and 6-month old roof were 6.3 and 14.6 times higher,respectively,than concentrations from the regular roof,and average PO_(4)^(3-)concentrations from the 6-year old roof and 6-month old roof were 13.5 and 26.6 times higher,respectively,compared to the regular roof.Runoff from the 6-month old green roof had higher concentrations of TP and PO_(4)^(3-)than the 6-year old green roof during the wet season,but lower concentrations during the dry season.The 6-month old green roof installations where receiving waters are sensitive or impaired may need additional treatment methods to reduce phosphorus levels.As green roofs age,water retention decreases and phosphorus leaching increases during the dry season.展开更多
智能反射面(Intelligent Reflecting Surface,IRS)可有效增强无线通信系统的鲁棒性。然而,信道估计开销巨大,且这些开销随IRS反射元数呈比例增加,增加了处理基于多个IRS辅助通信系统开销问题的难度。为此,提出基于反射控制模型的用户和...智能反射面(Intelligent Reflecting Surface,IRS)可有效增强无线通信系统的鲁棒性。然而,信道估计开销巨大,且这些开销随IRS反射元数呈比例增加,增加了处理基于多个IRS辅助通信系统开销问题的难度。为此,提出基于反射控制模型的用户和速率优化(Optimal Sum Rate of User Based on Reflection Control Pattern,OSRP)算法。构建反射控制模型,并根据反射链路的衰减信息,只选择部分IRS为用户提供反射服务,减少因估计信道状态信息(Channel State Information,CSI)产生的开销。依据不完备的CSI,优化波束赋形矩阵和IRS相位,进而提升用户和速率。仿真结果表明,相比于基于完备CSI的用户和速率优化算法,OSRP算法降低了算法的复杂度,提升了用户和速率。展开更多
基金supported by OHSU Neurology Foundation Funds and NIH Grant R01NS119226 to IM.
文摘Oxidative stress has long been implicated as a driving force in neurodegenerative disease,with studies of human brain tissue and animal models revealing its important role.Parkinson’s disease(PD),in particular,highlights the selective vulnerability of neurons to the insults of reactive oxygen species.The motor symptoms of PD are caused by degeneration of dopamine neurons in the substantia nigra.These neurons experience increased oxidative stress due in part to highly active mitochondria that support their high bioenergetic demand and the generation of reactive oxygen species by dopamine metabolism(Watanabe et al.,2024).
基金funded by the Office of the Vice-President for Research and Development of Cebu Technological University.
文摘This study demonstrates a novel integration of large language models,machine learning,and multicriteria decision-making to investigate self-moderation in small online communities,a topic under-explored compared to user behavior and platform-driven moderation on social media.The proposed methodological framework(1)utilizes large language models for social media post analysis and categorization,(2)employs k-means clustering for content characterization,and(3)incorporates the TODIM(Tomada de Decisão Interativa Multicritério)method to determine moderation strategies based on expert judgments.In general,the fully integrated framework leverages the strengths of these intelligent systems in a more systematic evaluation of large-scale decision problems.When applied in social media moderation,this approach promotes nuanced and context-sensitive self-moderation by taking into account factors such as cultural background and geographic location.The application of this framework is demonstrated within Facebook groups.Eight distinct content clusters encompassing safety,harassment,diversity,and misinformation are identified.Analysis revealed a preference for content removal across all clusters,suggesting a cautious approach towards potentially harmful content.However,the framework also highlights the use of other moderation actions,like account suspension,depending on the content category.These findings contribute to the growing body of research on self-moderation and offer valuable insights for creating safer and more inclusive online spaces within smaller communities.
基金primarily supported by Grant 2022066 from the U.S.-Israel Binational Science Foundation(BSF)support by the U.S.Department of Energy,Office of Science,Office of Basic Energy Sciences,under Award Number DESC0025485(material synthesis and structural characterization)+1 种基金supported by the U.S.DOE,Office of Basic Energy Sciences,under Contract No.DE-AC02-06CH11357the support from the US National Science Foundation through awards DMR-2317008。
文摘Metal halides are an important class of optoelectronic materials combining exceptional optical and electronic properties.An inherent advantage of metal halides is their solution synthesis and processability,which render them as low-cost and environmentally friendly materials for a range of applications from photovoltaics and photodetection to solid-state lighting(SSL).In this study,we synthesized three previously unreported lead-free organic–inorganic hybrid copper halides:(OA)_(4)CuX_(5)(X=Br,I;OA^(+) =C_(8)H_(17)NH_(3)^(+) ,n-octylammonium cation)and(HA)_(2)CuI_(3)(HA^(+) =C_(6)H_(13)NH_(3)^(+) ,n-hexylammonium cation),all of which exhibit broadband emissions arising from self-trapped excitons(STEs).Among these compounds,(OA)_(4)CuI_(5) demonstrates tunable dual-band white-light emission with a high color rendering index value of 91 at room temperature.Temperature-dependent photoluminescence measurements and first-principles calculations reveal distinct behaviors between the two emission states in(OA)_(4)CuI_(5).These findings highlight the potential of copper halide compounds for optoelectronic applications,particularly in the development of environmentally friendly solid-state lighting technologies.
基金supported by the National Key Research and Development Program of China (MOST)(Grant No.2022YFA1402800)the Chinese Academy of Sciences (CAS) Presidents International Fellowship Initiative (PIFI)(Grant No.2025PG0006)+3 种基金the National Natural Science Foundation of China (NSFC)(Grant Nos.51831012,12274437,and 52161160334)the CAS Project for Young Scientists in Basic Research (Grant No.YSBR-084)the CAS Youth Interdisciplinary Teamthe China Postdoctoral Science Foundation (Grant No.2025M773402)。
文摘Based on the Smit-Suhl formula,we propose a universal approach for solving the magnon-magnon coupling problem in bilayer coupled systems(e.g.,antiferromagnets).This method requires only the energy expression,enabling the automatic derivation of analytical expressions for the eigenmatrix elements via symbolic computation,eliminating the need for tedious manual calculations.Using this approach,we investigate the impact of magnetic hysteresis on magnon-magnon coupling in a system with interlayer Dzyaloshinskii-Moriya interaction(DMI).The magnetic hysteresis leads to an asymmetric magnetic field dependence of the resonance frequency and alters the number of degeneracy points between the pure optical and acoustic modes.Moreover,it can result in the coupling strength at the gap of the f–H phase diagram being nearly vanishing,contrary to the conventionally expected maximum.These results deepen the understanding of the effect of interlayer DMI on magnon–magnon coupling and the proposed universal method significantly streamlines the solving process of magnon–magnon coupling problems.
基金funded by the Oregon Alliance of Independent Colleges and Universities and the Shiley Fellows Fund.
文摘Green roofs have become a common method to increase water retention on-site in urban areas.However,the long-term water quality of runoff from green roofs is poorly understood.This study evaluated the water quality of stormwater runoff from a regular(non-vegetated)roof,a green roof installed 6 months previously,and a green roof installed 6 years ago in Portland,Oregon.Samples of runoff were taken during every rain event for 10 months,and analyzed for total phosphorus(TP),phosphate(PO_(4)^(3-)),total nitrogen(TN),nitrate(NO_(3)^(-)),ammonia(NH_(3)),copper(Cu),and zinc(Zn).Runoff from the green roofs had higher concentrations of TP and PO_(4)^(3-)and lower concentrations of Zn compared to the regular roof.Average TP concentrations from the 6-year old roof and 6-month old roof were 6.3 and 14.6 times higher,respectively,than concentrations from the regular roof,and average PO_(4)^(3-)concentrations from the 6-year old roof and 6-month old roof were 13.5 and 26.6 times higher,respectively,compared to the regular roof.Runoff from the 6-month old green roof had higher concentrations of TP and PO_(4)^(3-)than the 6-year old green roof during the wet season,but lower concentrations during the dry season.The 6-month old green roof installations where receiving waters are sensitive or impaired may need additional treatment methods to reduce phosphorus levels.As green roofs age,water retention decreases and phosphorus leaching increases during the dry season.
文摘智能反射面(Intelligent Reflecting Surface,IRS)可有效增强无线通信系统的鲁棒性。然而,信道估计开销巨大,且这些开销随IRS反射元数呈比例增加,增加了处理基于多个IRS辅助通信系统开销问题的难度。为此,提出基于反射控制模型的用户和速率优化(Optimal Sum Rate of User Based on Reflection Control Pattern,OSRP)算法。构建反射控制模型,并根据反射链路的衰减信息,只选择部分IRS为用户提供反射服务,减少因估计信道状态信息(Channel State Information,CSI)产生的开销。依据不完备的CSI,优化波束赋形矩阵和IRS相位,进而提升用户和速率。仿真结果表明,相比于基于完备CSI的用户和速率优化算法,OSRP算法降低了算法的复杂度,提升了用户和速率。
