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Dietary Patterns and Their Association with Depression among Type 2 Diabetes Patients in Gaza Strip, Palestine 被引量:1
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作者 Abdel Hamid el Bilbeisi Mohammed Srour +2 位作者 Amany el Afifi Halgord Ali M. Farag Kurosh Djafarian 《Food and Nutrition Sciences》 2019年第5期533-550,共18页
Background: Depression is a common mental disorder. Globally, more than 340 million people of all ages suffer from depression. The aim of our study was to determine the association between major dietary patterns and d... Background: Depression is a common mental disorder. Globally, more than 340 million people of all ages suffer from depression. The aim of our study was to determine the association between major dietary patterns and depression among type 2 diabetes patients. Methods: This cross-sectional study was conducted among 480 type 2 diabetes patients attending primary healthcare centers in Gaza Strip, Palestine. The depression, anxiety, stress scales (DASS, 21-items) questionnaire was used to measure the score of depression. The participants’ demographic, socioeconomic and medical history data was collected and the 98-items semi-quantitative food frequency questionnaire was used for evaluating the dietary patterns. Statistical analysis was performed using SPSS version 20. Results: Based on depression scale, 29.0% of type 2 diabetes patients had depression, (58.3% females, and 41.7% males). The prevalence of mild, moderate, severe, and very severe depression was 11.7%, 8.5%, 6.7%, and 2.1%, respectively. Furthermore, two major dietary patterns were identified by factor analysis: The Western, and the grains-vegetables, and fruits patterns. After adjusting for the potential confounders, patients in the lowest tertile (T1) of the grains-vegetables, and fruits dietary pattern had a lower odds for depression (OR 0.763 95% CI (0.667 - 0.871), P value = 0.001);where as a higher odds for healthy (OR 1.443 95% CI (1.131 - 1.839), P value = 0.004), compared to those in the highest tertile (T3). Conclusion: The grains-vegetables, and fruits dietary pattern may be associated with a lower prevalence of depression, and has been shown to be the healthiest dietary pattern among type 2 diabetes patients. 展开更多
关键词 DEPRESSION DIETARY Patterns Factor Analysis PREVALENCE Type 2 DIABETES MELLITUS
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Security Monitoring and Management for the Network Services in the Orchestration of SDN-NFV Environment Using Machine Learning Techniques 被引量:2
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作者 Nasser Alshammari Shumaila Shahzadi +7 位作者 Saad Awadh Alanazi Shahid Naseem Muhammad Anwar Madallah Alruwaili Muhammad Rizwan Abid Omar Alruwaili Ahmed Alsayat Fahad Ahmad 《Computer Systems Science & Engineering》 2024年第2期363-394,共32页
Software Defined Network(SDN)and Network Function Virtualization(NFV)technology promote several benefits to network operators,including reduced maintenance costs,increased network operational performance,simplified ne... Software Defined Network(SDN)and Network Function Virtualization(NFV)technology promote several benefits to network operators,including reduced maintenance costs,increased network operational performance,simplified network lifecycle,and policies management.Network vulnerabilities try to modify services provided by Network Function Virtualization MANagement and Orchestration(NFV MANO),and malicious attacks in different scenarios disrupt the NFV Orchestrator(NFVO)and Virtualized Infrastructure Manager(VIM)lifecycle management related to network services or individual Virtualized Network Function(VNF).This paper proposes an anomaly detection mechanism that monitors threats in NFV MANO and manages promptly and adaptively to implement and handle security functions in order to enhance the quality of experience for end users.An anomaly detector investigates these identified risks and provides secure network services.It enables virtual network security functions and identifies anomalies in Kubernetes(a cloud-based platform).For training and testing purpose of the proposed approach,an intrusion-containing dataset is used that hold multiple malicious activities like a Smurf,Neptune,Teardrop,Pod,Land,IPsweep,etc.,categorized as Probing(Prob),Denial of Service(DoS),User to Root(U2R),and Remote to User(R2L)attacks.An anomaly detector is anticipated with the capabilities of a Machine Learning(ML)technique,making use of supervised learning techniques like Logistic Regression(LR),Support Vector Machine(SVM),Random Forest(RF),Naïve Bayes(NB),and Extreme Gradient Boosting(XGBoost).The proposed framework has been evaluated by deploying the identified ML algorithm on a Jupyter notebook in Kubeflow to simulate Kubernetes for validation purposes.RF classifier has shown better outcomes(99.90%accuracy)than other classifiers in detecting anomalies/intrusions in the containerized environment. 展开更多
关键词 Software defined network network function virtualization network function virtualization management and orchestration virtual infrastructure manager virtual network function Kubernetes Kubectl artificial intelligence machine learning
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压光对纸张表面性能的影响 被引量:2
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作者 P.Vernhes M.Dubé +1 位作者 J.-F.Bloch 许英 《中国印刷与包装研究》 CAS 2010年第6期73-77,共5页
纸张压光是一道工业整饰工序,它可以提高纸张表面的平滑度,改善其光泽度和印刷适性。本文讨论了压光对微观和宏观尺度上纸张粗糙度的影响以及这种表面改性与纤维形态之间的关系。实验原料为两种不同的纤维以及它们的混合物,采用光学轮... 纸张压光是一道工业整饰工序,它可以提高纸张表面的平滑度,改善其光泽度和印刷适性。本文讨论了压光对微观和宏观尺度上纸张粗糙度的影响以及这种表面改性与纤维形态之间的关系。实验原料为两种不同的纤维以及它们的混合物,采用光学轮廓仪表征纸张表面的性能。实验结果表明,在所测定的尺度范围内,压光均可以改善纸张的表面性能,通过简单的比例转换后,这些变化具有相关性,这一结果也适用于由混合纤维抄造的纸张。 展开更多
关键词 压光技术 尺寸差异 天然纤维 纸张 形貌
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A Case Study of Heat Transfer from Hot Runner Mould to the Fix Platen of the Injection-moulding Machine
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作者 C H Tan K S Lee 《厦门大学学报(自然科学版)》 CAS CSCD 北大核心 2002年第S1期97-98,共2页
In an injection moulding process, the parallelism b et ween the tie bars of the injection moulding machine is very important as it will affect the mould closing and clamping system. In recent years, more and more ho t... In an injection moulding process, the parallelism b et ween the tie bars of the injection moulding machine is very important as it will affect the mould closing and clamping system. In recent years, more and more ho t runner systems are being applied in the moulding industry to save material and decrease the losses of injection pressure. Heat transfer from hot runner system from the fixed half which is secured in the fix machine platen could transmit s o much heat that it may cause high temperature differential between the machine fix platen and moving platen. This will cause the tie bar to become unparallel. Part quality will be compromised and the wear of the tie bar will be excessive. Overhaul of the tie bar may be necessary after a short period of time which is c ostly. This raises the need to analyze the heat transfer from the hot runner sys tem to the machine fix platen and the methods of isolating or minimizing the hea t transfer. In this case study, a photo lens article mould was used. The mould w as built with a direct hot runner nozzle system. Heat conduction from hot runner and machine screw to machine fix platen were studied based on either using high temperature heat insulating plate put in placed between the mould and the mould ing machine fix platen or drill cooling channels in the front mould clamping pla te. The high temperature insulator is very costly as it is made out of glass re inforced polymer composite material. Experimental results were obtained and anal yzed to find the best method to minimize the unwanted heat transfer using the ch eapest and most effective method. 展开更多
关键词 injection moulding COOLING hot runner system i njection moulding machine platen tie bar
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过程分析技术——医药行业的战略前景展望:在线分析的重要性正在不断提高
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作者 Michael Rudolph 《流程工业》 2006年第11期18-19,共2页
美国食品和药品监督管理局(FDA)倡议在流程工业生产过程中使用过程分析技术(PAT),在生产线中采取严格的工艺措施,从而为工艺流程的优化控制和低成本作业带来了新的机会。
关键词 在线分析 医药行业 技术 展望 工业生产过程 美国食品 工艺措施 优化控制
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Relationship between apoptotic markers in semen from fertile men and demographic, hormonal and seminal characteristics
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作者 Ina O Specht Marcello Spano +5 位作者 Karin S Hougaard Gian C Manicardi Davide Bizzaro Gunnar Toft Aleksander Giwercman Jens-Peter E Bonde 《Asian Journal of Andrology》 SCIE CAS CSCD 2012年第6期890-896,共7页
Apoptosis in the testis has two putative roles during normal spermatogenesis; limitation of the germ cell population to numbers that can be supported by the Sertoli cells, and, possibly, selective depletion of meiotic... Apoptosis in the testis has two putative roles during normal spermatogenesis; limitation of the germ cell population to numbers that can be supported by the Sertoli cells, and, possibly, selective depletion of meiotic and postmeiotic abnormal germ cells. We investigated the demographic and biological correlates of the pro-apoptotic marker Fas and the anti-apoptotic marker Bcl-xL in sperm cells of fertile men. Six hundred and four men from Greenland, Poland and Ukraine were consecutively enrolled during their pregnant wife's antenatal visits. Semen analysis was performed as recommended by the World Health Organization. Immunofluorescence coupled to flow cytometry was utilized for detection of apoptotic markers in the sperm cell. DNA damage was assessed by flow cytometry using both the sperm chromatin structure assay (SCSA) and the terminal deoxynucleotidyl transferase dUTP nick end labelling (TUNEL) assay. The percentage of Fas-positive sperm cells was higher in men with high total sperm count (P〈O.01), more motile sperms (P=-O.04) and fewer sperm head defects (P=-O.05). These associations were consistent within and across study regions. Furthermore, testosterone, follicle-stimulating hormone (FSH) and sexual hormone-binding globulin (SHBG) were significantly negatively correlated with Fas within and across regions as well. The data indicated no association between the anti-apoptotic Bcl-xL marker and semen or personal characteristics. The finding of Fas-positive sperm cells associated with better semen quality in a cohort of spouses of pregnant women seems different from previous data obtained in infertile men and warrants further investigation to clarify the biological significance of sperm apoptotic markers. 展开更多
关键词 apoptosis Bcl-x protein Fas-associated death domain protein FERTILITY sperm chromatin structure assay (SCSA) sper- matozoa TUN EL assay
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Role of semi-purified andrographolide from Andrographis paniculata extract as nano-phytovesicular carrier for enhancing oral absorption and hypoglycemic activity 被引量:2
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作者 Vinod Kumar Verma Md.Kamaruz Zaman +2 位作者 Shekhar Verma Santosh Kumar Verma Khomendra Kumar Sarwa 《Chinese Herbal Medicines》 CAS 2020年第2期142-155,共14页
Objective:Andrographis paniculata is a well-known medicinal plant in Southeast Asia,India and China.The plant contains andrographolide(AN),a very important phytochemical used in various health problems.However,AN is l... Objective:Andrographis paniculata is a well-known medicinal plant in Southeast Asia,India and China.The plant contains andrographolide(AN),a very important phytochemical used in various health problems.However,AN is low in oral absorption bioavailability of AN due to the rapid clearance and high protein binding capacity.Methods:The present study was aimed to develop a nano-phytovesicular formulation of semi-purified AN extracts from a naturally occurring phospholipid(soya phosphatidylcholine)in order to increase the oral absorption and antihyperglycemic activity in rats.Results:The nano-phyto vesicle of semi-purified AN extracts equivalent to 25 mg/kg AN significantly protected the hyperglycemic condition of rats.The in vitro and in vivo experiments results proved that the nano-phytovesicular system of plant extracts containing AN produced better oral absorption,bioavailability and improved antihyperglycemic activity compared with that of free AN at dose of 50 mg/kg.Conclusion:Hence,the prepared semi-purified extract nano-phytovesicular system is helpful in solving the problem of rapid clearance of AN. 展开更多
关键词 Andrographis paniculata(Burm.f.)Nees ANDROGRAPHOLIDE hypoglycemic activity liquid dispersion nano-phyto vesicle soya phosphatidylcholine
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Self-aligned single-electrode actuation of tangential and wineglass modes using PMN-PT
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作者 Ozan Erturk Kilian Shambaugh +2 位作者 Ha-Seong Park Sang-Goo Lee Sunil A.Bhave 《Microsystems & Nanoengineering》 SCIE CSCD 2023年第3期43-49,共7页
Considering the evolution of rotation sensing and timing applications realized in micro-electro-mechanical systems(MEMS),flexural mode resonant shapes are outperformed by bulk acoustic wave(BAW)counterparts by achievi... Considering the evolution of rotation sensing and timing applications realized in micro-electro-mechanical systems(MEMS),flexural mode resonant shapes are outperformed by bulk acoustic wave(BAW)counterparts by achieving higher frequencies with both electrostatic and piezoelectric transduction.Within the 1-30 MHz range,which hosts BAW gyroscopes and timing references,piezoelectric and electrostatic MEMS have similar transduction efficiency.Although,when designed intelligently,electrostatic transduction allows self-alignment between electrodes and the resonator for various BAW modes,misalignment is inevitable regarding piezoelectric transduction of BAW modes that require electrode patterning.In this paper transverse piezoelectric actuation of[011]oriented single crystal lead magnesium niobate-lead titanate(PMN-PT)thin film disks are shown to excite the tangential mode and family of elliptical compound resonant modes,utilizing a self-aligned and unpatterned electrode that spans the entire disk surface.The resonant mode coupling is achieved by employing a unique property of[011]PMN-PT,where the in-plane piezoelectric coefficients have opposite signs.Fabricating 1-port disk transducers,RF reflection measurements are performed that demonstrate the compound mode family shapes in the 1-30 MHz range.Independent verification of mode transduction is achieved using in-plane displacement measurements with Polytec’s laser Doppler vibrometer(LDV).While the tangential mode achieves a 40°/s dithering rate at 335 kHz resonant frequency,the n=2 wine-glass mode achieves 11.46 nm tip displacement at 8.42 MHz resonant frequency on a radius of 60μm disk resonator in air.A single electrode resonator that can excite both tangential and wine-glass modes with such metrics lays the foundation for a BAW MEMS gyroscope with a built-in primary calibration stage. 展开更多
关键词 RESONATOR ELECTRODE piezoelectric
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Nanomechanical thermometry for probing sub-nW thermal transport
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作者 Sangmin Oh Nehpal Singh Shekhawat +2 位作者 Osama Jameel Amit Lal Chung Hoon Lee 《Microsystems & Nanoengineering》 CSCD 2024年第5期287-303,共17页
Accurate local temperature measurement at micro and nanoscales requires thermometry with high resolution because of ultra-low thermal transport.Among the various methods for measuring temperature,optical techniques ha... Accurate local temperature measurement at micro and nanoscales requires thermometry with high resolution because of ultra-low thermal transport.Among the various methods for measuring temperature,optical techniques have shown the most precise temperature detection,with resolutions reaching(-10^(-9) K).In this work,we present a nanomechanical device with nano-Kelvin resolution(-10^(-9) K)at room temperature and 1 atm.The device uses a 20 nm thick silicon nitride(SiN)membrane,forming an air chamber as the sensing area.The presented device has a temperature sensing area>1 mm^(2)for micro/nanoscale objects with reduced target placement constraints as the target can be placed anywhere on the>1 mm^(2)sensing area.The temperature resolution of the SiN membrane device is determined by deflection at the center of the membrane.The temperature resolution is inversely proportional to the membrane's stiffness,as detailed through analysis and measurements of stiffness and noise equivalent temperature(NET)in the pre-stressed SiN membrane.The achievable heat flow resolution of the membrane device is 100 pW,making it suitable for examining thermal transport on micro and nanoscales. 展开更多
关键词 TRANSPORT STIFFNESS PRECISE
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Integrated heterodyne laser Doppler vibrometer based on stress-optic frequency shift in silicon nitride
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作者 Adam Raptakis Lefteris Gounaridis +21 位作者 Jörn P.Epping Thi Lan Anh Tran Thomas Aukes Moritz Kleinert Madeleine Weigel Marco Wolfer Alexander Draebenstedt Christos Tsokos Panos Groumas Efstathios Andrianopoulos Nikos Lyras Dimitrios Nikolaidis Elias Mylonas Nikolaos Baxevanakis Roberto Pessina Erik Schreuder Matthijn Dekkers Volker Seyfried Norbert Keil RenéG.Heideman Hercules Avramopoulos Christos Kouloumentas 《PhotoniX》 SCIE EI 2023年第1期145-171,共27页
We demonstrate a compact heterodyne Laser Doppler Vibrometer (LDV) based on the realization of optical frequency shift in the silicon nitride photonic integration platform (TriPleX). We theoretically study, and experi... We demonstrate a compact heterodyne Laser Doppler Vibrometer (LDV) based on the realization of optical frequency shift in the silicon nitride photonic integration platform (TriPleX). We theoretically study, and experimentally evaluate two different photonic integrated optical frequency shifters (OFSs), utilizing serrodyne and single- sideband (SSB) modulation. Both OFSs employ stress-optic modulators (SOMs) based on the non-resonant piezoelectrical actuation of lead zirconate titanate (PZT) thin- films, deposited on top of the silicon nitride waveguides with a wafer-scale process. To improve the modulation bandwidth of the SOMs we investigate a novel configuration of the electrodes used for the actuation, where both electrodes are placed on top of the PZT layer. Using this top-top electrode configuration we report frequency shift of 100 kHz and 2.5 MHz, and suppression ratio of the unwanted sidebands of 22.1 dB and 39 dB, using the serrodyne and the SSB OFS, respectively. The best performing SOM structure induces 0.25π peak-to-peak sinusoidal phase-shift with 156 mW power dissipation at 2.5 MHz. We use the SSB-OFS in our compact LDV system to demonstrate vibration measurements in the kHz regime. The system comprises a dual-polarization coherent detector built in the PolyBoard platform, utilizing hybrid integration of InP photodiodes (PDs). High quality LDV performance with measurement of vibration frequencies up to several hundreds of kHz and displacement resolution of 10 pm are supported with our system. 展开更多
关键词 Photonic integration Optical frequency shift Stress-optic PZT Silicon nitride Heterodyne interferometry Laser doppler vibrometry
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Lamb wave-based corrosion source location on a plate of magnesium alloy WZ73 using the acoustic emission technique
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作者 Marcel Mandel Marco Fritzsche +1 位作者 Sebastian Henschel Lutz Krüger 《Corrosion Communications》 2024年第1期60-67,共8页
Corrosion on a plate of magnesium alloy WZ73 in contact with 0.001 mol/L NaCl solution was analysed by long-range testing using the acoustic emission(AE)technique.At a distance d=1.66 m to the source,the Lamb wave pro... Corrosion on a plate of magnesium alloy WZ73 in contact with 0.001 mol/L NaCl solution was analysed by long-range testing using the acoustic emission(AE)technique.At a distance d=1.66 m to the source,the Lamb wave propagation of resulting AE events was examined and used for corrosion source location.As a first step,pencil lead break test was carried out and corresponding Lamb wave analysis served as reference to the varying corrosion signals of lower intensity.Additionally,the plate was excited by a piezo transducer for imitating a selected corrosion event.For analysis of the propagating wave field,the plate surface was measured by a scanning laser Doppler vibrometer(SLDV),allowing a high-resolution corrosion signal reconstruction and path tracking of direct and reflected Lamb wave packets.Based on the SLDV results,a deeper understanding of the complex wave field propagation during the sensor-based corrosion analysis was achieved. 展开更多
关键词 Acoustic emission CORROSION Health monitoring Guided wave WAVELET
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