Cyanide poisoning is one of the most dangerous poisonings, and it can be absorbed into the body through the mouth, inhalation and through the skin. A 32-year-old female patient was admitted to our poison control cente...Cyanide poisoning is one of the most dangerous poisonings, and it can be absorbed into the body through the mouth, inhalation and through the skin. A 32-year-old female patient was admitted to our poison control center because of high fever, severe vomiting, and seizures. Physical examination found that the patient was drowsy, had a high fever of 40 degrees Celsius, pulse of 140 beats/minute, and increased tendon and bone reflexes. Exploiting the patient’s information, it was discovered that the patient bought Cyanide to drink with the intention of committing suicide. The patient was quickly treated with gastric lavage and activated charcoal. Echocardiography recorded EF: 35%, reduced movement of the entire myocardium. CK blood test: 4562 U/L. The patient’s condition rapidly deteriorated and the patient was made ECMO, IHD and CVVHDF. After 3 days of treatment, the patient’s condition did not improve, so the family asked for the patient to go home. This article aims to describe the rapidly progressing and severe damage to the heart and muscles of patients with cyanide poisoning.展开更多
The issue of plastic pollutants has become a growing concern.Both microplastics(MPs)(particle size<5 mm)and nanoplastics(NPs)(particle size<1μm)can cause DNA damage,cytotoxicity,and oxidative stress in various ...The issue of plastic pollutants has become a growing concern.Both microplastics(MPs)(particle size<5 mm)and nanoplastics(NPs)(particle size<1μm)can cause DNA damage,cytotoxicity,and oxidative stress in various organisms.The primary known impacts of microplastic/nanoplastic are observed in the liver and respiratory system,leading to hepatotoxicity and chronic obstructive pulmonary disease.Although research on the effects of MPs and NPs on diabetes is still in its early stages,there are potential concerns.This editorial highlights the risk to diabetics from co-exposure to contaminants and MPs/NPs,supported by evidence from animal studies and the various chemical compositions of MPs/NPs.展开更多
目的研究2019年北京市食源性单增李斯特菌的分子特征和耐药性。方法采用多重PCR进行血清群分型,分离的56株菌株经脉冲场凝胶电泳(pulsed field gel electrophoresis,PFGE)、多位点序列分析(multilocus sequence typing,MLST)鉴定,使用...目的研究2019年北京市食源性单增李斯特菌的分子特征和耐药性。方法采用多重PCR进行血清群分型,分离的56株菌株经脉冲场凝胶电泳(pulsed field gel electrophoresis,PFGE)、多位点序列分析(multilocus sequence typing,MLST)鉴定,使用微量肉汤法检测菌株的耐药性。结果56株单增李斯特菌中有28株分离自冷锅串串和中式凉拌菜,1/2a,3a是主要的血清群。56株菌共分为29个PFGE带型、14个ST型,ST9、ST5、ST8、ST121是优势ST型。2株菌对环丙沙星耐药,1株菌对四环素耐药。结论冷锅串串和中式凉拌菜是单增李斯特菌污染的高危食品。北京市食品来源单增李斯特菌的ST型别与国内其他地方食品来源菌株一致,与北京市临床分离株一致。展开更多
文摘Cyanide poisoning is one of the most dangerous poisonings, and it can be absorbed into the body through the mouth, inhalation and through the skin. A 32-year-old female patient was admitted to our poison control center because of high fever, severe vomiting, and seizures. Physical examination found that the patient was drowsy, had a high fever of 40 degrees Celsius, pulse of 140 beats/minute, and increased tendon and bone reflexes. Exploiting the patient’s information, it was discovered that the patient bought Cyanide to drink with the intention of committing suicide. The patient was quickly treated with gastric lavage and activated charcoal. Echocardiography recorded EF: 35%, reduced movement of the entire myocardium. CK blood test: 4562 U/L. The patient’s condition rapidly deteriorated and the patient was made ECMO, IHD and CVVHDF. After 3 days of treatment, the patient’s condition did not improve, so the family asked for the patient to go home. This article aims to describe the rapidly progressing and severe damage to the heart and muscles of patients with cyanide poisoning.
基金Supported by Research grant from Chang Gung Memorial Hospital,Linkou,Taiwan,No.CMRPG3N0622.
文摘The issue of plastic pollutants has become a growing concern.Both microplastics(MPs)(particle size<5 mm)and nanoplastics(NPs)(particle size<1μm)can cause DNA damage,cytotoxicity,and oxidative stress in various organisms.The primary known impacts of microplastic/nanoplastic are observed in the liver and respiratory system,leading to hepatotoxicity and chronic obstructive pulmonary disease.Although research on the effects of MPs and NPs on diabetes is still in its early stages,there are potential concerns.This editorial highlights the risk to diabetics from co-exposure to contaminants and MPs/NPs,supported by evidence from animal studies and the various chemical compositions of MPs/NPs.
文摘目的研究2019年北京市食源性单增李斯特菌的分子特征和耐药性。方法采用多重PCR进行血清群分型,分离的56株菌株经脉冲场凝胶电泳(pulsed field gel electrophoresis,PFGE)、多位点序列分析(multilocus sequence typing,MLST)鉴定,使用微量肉汤法检测菌株的耐药性。结果56株单增李斯特菌中有28株分离自冷锅串串和中式凉拌菜,1/2a,3a是主要的血清群。56株菌共分为29个PFGE带型、14个ST型,ST9、ST5、ST8、ST121是优势ST型。2株菌对环丙沙星耐药,1株菌对四环素耐药。结论冷锅串串和中式凉拌菜是单增李斯特菌污染的高危食品。北京市食品来源单增李斯特菌的ST型别与国内其他地方食品来源菌株一致,与北京市临床分离株一致。
