In this review,we summarize the recent microbiome studies related to diabetes disease and discuss the key findings that show the early emerging potential causal roles for diabetes.On a global scale,diabetes causes a s...In this review,we summarize the recent microbiome studies related to diabetes disease and discuss the key findings that show the early emerging potential causal roles for diabetes.On a global scale,diabetes causes a significant negative impact to the health status of human populations.This review covers type 1 diabetes and type 2 diabetes.We examine promising studies which lead to a better understanding of the potential mechanism of microbiota in diabetes diseases.It appears that the human oral and gut microbiota are deeply interdigitated with diabetes.It is that simple.Recent studies of the human microbiome are capturing the attention of scientists and healthcare practitioners worldwide by focusing on the interplay of gut microbiome and diabetes.These studies focus on the role and the potential impact of intestinal microflora in diabetes.We paint a clear picture of how strongly microbes are linked and associated,both positively and negatively,with the fundamental and essential parts of diabetes in humans.The microflora seems to have an endless capacity to impact and transform diabetes.We conclude that there is clear and growing evidence of a close relationship between the microbiota and diabetes and this is worthy of future investments and research efforts.展开更多
In response to the problem of how to give geographic information system(GIS)high-performance capabilities for certain specific GIS applications,a new GIS research direction,parallel GIS processing,has emerged.However,...In response to the problem of how to give geographic information system(GIS)high-performance capabilities for certain specific GIS applications,a new GIS research direction,parallel GIS processing,has emerged.However,traditional research has focused mostly on implementing typical GIS parallel algorithms,with little discussion of how to parallelize an entire GIS package on clusters based on theory.Therefore,the authors have chosen the geographic resources analysis support system(GRASS)GIS as the object of their research and have put forward the concept of a cluster-based open-source parallel GIS(cluster-based OP-GIS)as a tool to support Digital Earth construction.The related theory includes not only the parallel computing mode,architecture,and software framework of such a system,but also various parallelization patterns.From experiments on the prototype system,it can be concluded that the parallel system has better efficiency and performance than the conventional system on certain selected modules.展开更多
基金Supported by Shandong Provincial Key Research and Development Program,No.2018CXGC1219City of Weihai Technique Extension Project,No.2016GNS023+1 种基金TaiShan Scholars Program of Shandong Province,No.tshw20120206TaiShan Industrial Experts Program,No.tscy20190612.
文摘In this review,we summarize the recent microbiome studies related to diabetes disease and discuss the key findings that show the early emerging potential causal roles for diabetes.On a global scale,diabetes causes a significant negative impact to the health status of human populations.This review covers type 1 diabetes and type 2 diabetes.We examine promising studies which lead to a better understanding of the potential mechanism of microbiota in diabetes diseases.It appears that the human oral and gut microbiota are deeply interdigitated with diabetes.It is that simple.Recent studies of the human microbiome are capturing the attention of scientists and healthcare practitioners worldwide by focusing on the interplay of gut microbiome and diabetes.These studies focus on the role and the potential impact of intestinal microflora in diabetes.We paint a clear picture of how strongly microbes are linked and associated,both positively and negatively,with the fundamental and essential parts of diabetes in humans.The microflora seems to have an endless capacity to impact and transform diabetes.We conclude that there is clear and growing evidence of a close relationship between the microbiota and diabetes and this is worthy of future investments and research efforts.
基金This work was supported by the Fundamental Research Funds for the Central Universities(Grant No.ZYGX2009J073)the National Natural Science Foundation of China(Grant No.41001221&40701146)+1 种基金also the National High-Tech R&D Program of China(Grant No.2007AA12Z227)Thanks to Anthony Lewis,the Letters Editor of IJDE,and the anonymous reviewers for their positive and constructive suggestions to improve the paper.
文摘In response to the problem of how to give geographic information system(GIS)high-performance capabilities for certain specific GIS applications,a new GIS research direction,parallel GIS processing,has emerged.However,traditional research has focused mostly on implementing typical GIS parallel algorithms,with little discussion of how to parallelize an entire GIS package on clusters based on theory.Therefore,the authors have chosen the geographic resources analysis support system(GRASS)GIS as the object of their research and have put forward the concept of a cluster-based open-source parallel GIS(cluster-based OP-GIS)as a tool to support Digital Earth construction.The related theory includes not only the parallel computing mode,architecture,and software framework of such a system,but also various parallelization patterns.From experiments on the prototype system,it can be concluded that the parallel system has better efficiency and performance than the conventional system on certain selected modules.
