Objective: to explore the nursing safety and safeguard measures for patients undergoing daytime operation. Methods: a total of 30 daytime operation patients who received treatment in our hospital in recent years were ...Objective: to explore the nursing safety and safeguard measures for patients undergoing daytime operation. Methods: a total of 30 daytime operation patients who received treatment in our hospital in recent years were selected as the research objects, and they were randomly and evenly divided into the research group and the control group, and then received routine nursing and nursing safety intervention respectively, and the nursing effects of the two groups of patients were compared and analyzed. Results: in practice, it was found that the occurrence rate of risk factors and delayed discharge rate of patients in the study group were lower than those in the control group. Conclusion: therefore, in the process of carrying out nursing work for patients undergoing daytime operation, strengthening nursing safety intervention can greatly improve the nursing work efficiency of patients undergoing operation.展开更多
The Dimbokro health district has one of the highest incidences of malaria in Côte d’Ivoire, despite numerous campaigns to distribute Long-Acting Impregnated Mosquito Nets (LLINs). Given this observation, what ar...The Dimbokro health district has one of the highest incidences of malaria in Côte d’Ivoire, despite numerous campaigns to distribute Long-Acting Impregnated Mosquito Nets (LLINs). Given this observation, what are the population’s attitudes towards LLINs that could explain the high endemicity of malaria in Dimbokro? The aim of this study is to assess the knowledge, attitudes and practices of people in the health area of Nofou, one of the villages in the Dimbokro health district where malaria is most prevalent, with a view to strengthening malaria control strategies. A collection of historical health data (malaria cases and LLIN usage rates) and a cross-sectional questionnaire survey was carried out from July 20 to August 03, 2022 in 400 households selected by systematic random sampling. Data were entered using Epi Info 7 and multivariate statistical analyses were performed using IBM SPSS 22 software. In the Dimbokro health district, the rate of LLIN use was negatively correlated (r = -0.771) with malaria incidence over the six years of historical data collection. Households had an average of 53% good knowledge, 68.6% good practices and 28.4% good attitudes towards LLINs. The study also revealed that the main factors explaining LLIN use in the Nofou health area are mosquito bite (ORa = 5.29 (1.12 - 25.04)), age of household members (ORa = 1.07 (1.01 - 1.14)) and marital status (ORa = 8.45 (1.70 - 45.02)). Awareness-raising on the use of LLINs should be intensified in the Dimbokro health district. Other control strategies, such as vector control and environmental sanitation, should be considered to combat malaria.展开更多
The gas kick represents a major risk in deepwater oil and gas exploration.Understanding the dynamics of gas kick evolution and the associated pressure response characteristics is critical for effective well control.In...The gas kick represents a major risk in deepwater oil and gas exploration.Understanding the dynamics of gas kick evolution and the associated pressure response characteristics is critical for effective well control.In this paper,we introduce a transient wellbore multiphase flow model specifically developed to simulate gas kick in deepwater dual-gradient drilling,incorporating a downhole separator.The model accounts for the variable mass flow within the annulus and heat exchange between the annular fluid and the formation.Using this model,we analyzed the multiphase flow and thermodynamic behavior during the gas kick.Simulation results reveal a progressive increase in bottom-hole temperature,underscoring its potential as a key indicator for gas kick early detection.Additionally,variable gradient parameters affect not only the annular equivalent circulating density(ECD)profile but also the evolution of the gas kick.The inclusion of a downhole separator alters the annular ECD profile,creating a“broken line”shape,which enhances adaptability to the multi-pressure systems typically encountered in deepwater forma-tion.By adjusting factors such as hollow sphere concentration,separator position,and separation effi-ciency,the annular ECD profile can be effectively customized.This study provides important theoretical insights and practical applications for utilizing dual-gradient drilling technology to address challenges in deepwater formation drilling.展开更多
Satellite Internet(SI)provides broadband access as a critical information infrastructure in 6G.However,with the integration of the terrestrial Internet,the influx of massive terrestrial traffic will bring significant ...Satellite Internet(SI)provides broadband access as a critical information infrastructure in 6G.However,with the integration of the terrestrial Internet,the influx of massive terrestrial traffic will bring significant threats to SI,among which DDoS attack will intensify the erosion of limited bandwidth resources.Therefore,this paper proposes a DDoS attack tracking scheme using a multi-round iterative Viterbi algorithm to achieve high-accuracy attack path reconstruction and fast internal source locking,protecting SI from the source.Firstly,to reduce communication overhead,the logarithmic representation of the traffic volume is added to the digests after modeling SI,generating the lightweight deviation degree to construct the observation probability matrix for the Viterbi algorithm.Secondly,the path node matrix is expanded to multi-index matrices in the Viterbi algorithm to store index information for all probability values,deriving the path with non-repeatability and maximum probability.Finally,multiple rounds of iterative Viterbi tracking are performed locally to track DDoS attack based on trimming tracking results.Simulation and experimental results show that the scheme can achieve 96.8%tracking accuracy of external and internal DDoS attack at 2.5 seconds,with the communication overhead at 268KB/s,effectively protecting the limited bandwidth resources of SI.展开更多
Objective: To identify the principal factors associated with the occurrence and development of medical device-related pressure injuries (MDRPI) in adults admitted to hospitals. MDRPI, a peculiar subtype of pressure in...Objective: To identify the principal factors associated with the occurrence and development of medical device-related pressure injuries (MDRPI) in adults admitted to hospitals. MDRPI, a peculiar subtype of pressure injuries (PI), result from the pression exerted by devices (or their fixation systems) applied for diagnostic and therapeutic purposes. MDRPI represent a serious problem for patients and healthcare systems. Understanding potential risk factors is an important step in implementing effective interventions. Methods: In this study, we will perform a systematic review;if possible, also a meta-analysis will be performed. The review will follow the preferred reporting items for systematic reviews and meta-analyses (PRISMA) reporting guidelines for systematic reviews. A rigorous literature search will be conducted both in electronic databases (Medline/PubMed, Embase, CINAHL, Web of Science, Scopus, Cochrane Library) to identify studies published since 2000 and in gray literature for unpublished studies. Pairs of researchers will identify relevant evidence, extract data, and assess risk of bias independently in each eligible study. Factors associated with the occurrence of MDRPI are considered the primary outcome. Secondary outcomes are prevalence and incidence of MDRPI, length of hospital stay, infections, and death. The evidence will be synthesized using the GRADE methodology. Results: Results are not currently available as this is a protocol for a systematic review. Conclusions: This systematic review will identify evidence on risk factors for developing MDRPI. We are confident that the results of this review will help to improve clinical practice and guide future research.展开更多
While the significant role of technological innovation in promoting renewable energy has been extensively explored in the literature,limited attention has been paid to the impact of energy patents,particularly clean e...While the significant role of technological innovation in promoting renewable energy has been extensively explored in the literature,limited attention has been paid to the impact of energy patents,particularly clean energy patents and fossil fuel patents.This study pioneers an investigation into the effects of energy patents and energy prices on renewable energy consumption.The study utilizes data from 2000Q1 to 2023Q4 and,due to the nonlinear nature of the series,applies wavelet quantile-based methods.Specifically,it introduces the wavelet quantile cointegration approach to evaluate cointegration across different quantiles and time horizons,along with the wavelet quantile-on-quantile regression method.The results confirm cointegration across different periods and quantiles,highlighting the significant relationships between energy patents,economic factors,and renewable energy consumption.Furthermore,we found that fossil energy patents negatively affect renewable energy consumption,while clean energy patents have a similar but weaker effect,especially in the short term.In addition,higher energy prices promote renewable energy adoption while economic growth positively influences renewable energy consumption,particularly in the short term.The study formulates specific policies based on these findings.展开更多
In the leakage detection of reservoir dam bodies,traditional geophysical methods can only achieve one-time detection.Meanwhile,due to the non-uniqueness of geophysicalin version,how to improve the fidelity of geophysi...In the leakage detection of reservoir dam bodies,traditional geophysical methods can only achieve one-time detection.Meanwhile,due to the non-uniqueness of geophysicalin version,how to improve the fidelity of geophysical detection inversion profiles has become a key challenge in the industry.This study aims to construct a long-term real-time monitoring system using the time-lapse resistivity method,reveal the spatiotemporal evolution law of dam leakage,and provide technical support for accurate treatment.By integrating the Internet of Things(IoT),5G technology,and AI technology,real-time data acquisition,real-time transmission,and automatic inversionare realized.Through dynamic imaging analysis of the electrical anomaly characteristics of the leakage area and comparison between corresponding rainfall events,the leakage range and resistivity changes,the reliability and efficiency of dam leakagedete ction are significantly improved.This achieves long-termdynamic monitoring of dam leakage and provides a new perspective for the safe operation and maintenance of reservoirs.展开更多
Air traffic flow management has been a major means for balancing air traffic demandand airport or airspace capacity to reduce congestion and flight delays.However,unpredictable fac-tors,such as weather and equipment m...Air traffic flow management has been a major means for balancing air traffic demandand airport or airspace capacity to reduce congestion and flight delays.However,unpredictable fac-tors,such as weather and equipment malfunctions,can cause dynamic changes in airport and sectorcapacity,resulting in significant alterations to optimized flight schedules and the calculated pre-departure slots.Therefore,taking into account capacity uncertainties is essential to create a moreresilient flight schedule.This paper addresses the flight pre-departure sequencing issue and intro-duces a capacity uncertainty model for optimizing flight schedule at the airport network level.The goal of the model is to reduce the total cost of flight delays while increasing the robustnessof the optimized schedule.A chance-constrained model is developed to address the capacity uncer-tainty of airports and sectors,and the significance of airports and sectors in the airport network isconsidered when setting the violation probability.The performance of the model is evaluated usingreal flight data by comparing them with the results of the deterministic model.The development ofthe model based on the characteristics of this special optimization mechanism can significantlyenhance its performance in addressing the pre-departure flight scheduling problem at the airportnetwork level.展开更多
As social interest in the environmental conservation and ecological restoration has recently increased, more research works have been done to resolve problems concerning environmental management of estuaries. In this ...As social interest in the environmental conservation and ecological restoration has recently increased, more research works have been done to resolve problems concerning environmental management of estuaries. In this study, a three-dimensional numerical model, Environmental Fluid Dynamics Code （EFDC） was used in the analysis of the salinity intrusion characteristics in the downstream of Geum River. The numerical simulation was performed to investigate the influence range for salinity intrusion when the gates were fully opened. The conditions used for simulation were the four flow regimes in Geum River Basin, Korea. Results indicated that the ranges of salinity intrusion from the barrage were 50.72 km （drought flow）, 48.87 km （low flow）, 46.56 km （normal flow） and 42.10 km （flood flow）. These results indicated that the EFDC model used for numerical simulation has high accuracy. The result concluded in this study can be used as a basis in understanding the extent of salinity intrusion effects at different flow rates.展开更多
After decades of research and development, the WSR-88 D(NEXRAD) network in the United States was upgraded with dual-polarization capability, providing polarimetric radar data(PRD) that have the potential to improve we...After decades of research and development, the WSR-88 D(NEXRAD) network in the United States was upgraded with dual-polarization capability, providing polarimetric radar data(PRD) that have the potential to improve weather observations,quantification, forecasting, and warnings. The weather radar networks in China and other countries are also being upgraded with dual-polarization capability. Now, with radar polarimetry technology having matured, and PRD available both nationally and globally, it is important to understand the current status and future challenges and opportunities. The potential impact of PRD has been limited by their oftentimes subjective and empirical use. More importantly, the community has not begun to regularly derive from PRD the state parameters, such as water mixing ratios and number concentrations, used in numerical weather prediction(NWP) models.In this review, we summarize the current status of weather radar polarimetry, discuss the issues and limitations of PRD usage, and explore potential approaches to more efficiently use PRD for quantitative precipitation estimation and forecasting based on statistical retrieval with physical constraints where prior information is used and observation error is included. This approach aligns the observation-based retrievals favored by the radar meteorology community with the model-based analysis of the NWP community. We also examine the challenges and opportunities of polarimetric phased array radar research and development for future weather observation.展开更多
To enable local water resource management and maintenance of ecosystem integrity and to protect and mitigate against flood and drought, it is necessary to determine changes in long-term series of streamflow and to dis...To enable local water resource management and maintenance of ecosystem integrity and to protect and mitigate against flood and drought, it is necessary to determine changes in long-term series of streamflow and to distinguish the roles that climate change and human disturbance play in these changes. A review of previous research on the detection and attribution of observed changes in annual runoff in China shows a decrease in annual runoff since the 1950s in northern China in areas such as the Songhuajiang River water resources zone, the Liaohe River water resources zone, the Haihe River water resources zone, the Yellow River water resources zone, and the Huaihe River water resources Zone. Furthermore, abrupt changes in annual runoff occurred mostly in the 1970s and 1980s in all the above zones, except for some of the sub-basins in the middle Yellow River where abrupt change occurred in the 1990s. Changes in annual runoff are found to be mainly caused by climate change in the western Songhuajiang River basin, the upper mainstream of the Yangtze River, and the western Pearl River basin, which shows that studies on the impact of climate change on future water resources under different climate change scenarios are required to enable planning and management by agencies in these river basins. However, changes in annual runoff were found to be mainly caused by human activities in most of the catchments in northern China (such as the southern Songhuajiang River, Liaohe River, Haihe River, the lower reach and some of the catchments within the middle Yellow River basin) and in middle-eastern China, such as the Huaihe River and lower mainstream of the Yangtze River. This suggests that current hydro-climatic data can continue to be used in water-use planning and that policymakers need to focus on water resource management and protection.展开更多
The analysis centers of the Multi-GNSS Pilot Project of the International GNSS Service provide orbit and clock products for the global navigation satellite systems(GNSSs)Global Positioning System(GPS),GLONASS,Galileo,...The analysis centers of the Multi-GNSS Pilot Project of the International GNSS Service provide orbit and clock products for the global navigation satellite systems(GNSSs)Global Positioning System(GPS),GLONASS,Galileo,and BeiDou,as well as for the Japanese regional Quasi-Zenith Satellite System(QZSS).Due to improved solar radiation pressure modeling and other more sophisticated models,the consistency of these products has improved in recent years.The current orbit consistency between different analysis centers is on the level of a few centimeters for GPS,around one decimeter for GLONASS and Galileo,a few decimeters for BeiDou-2,and several decimeters for QZSS.The clock consistency is about 2 cm for GPS,5 cm for GLONASS and Galileo,and 10 cm for BeiDou-2.In terms of carrier phase modeling error for precise point positioning,the various products exhibit consistencies of 2–3 cm for GPS,6–14 cm for GLONASS,3–10 cm for Galileo,and 10–17 cm for BeiDou-2.展开更多
The failure of a drilling pump is always due to the break of the drilling pump valve, which is one of the most important but also the weakest parts of the drilling pump. Over the decades, the degradation of drilling p...The failure of a drilling pump is always due to the break of the drilling pump valve, which is one of the most important but also the weakest parts of the drilling pump. Over the decades, the degradation of drilling pump valves has been investigated extensively and various failure mechanisms have been proposed. However, no experimental test on the fluid has been successfully performed to support some of these mechanisms. In this paper, tests of the flow within the valve play are carried out to investigate the factors resulting in the failure of the valve. In the tests, particle image velocimetry（PIV） technology is employed to measure the flow field distribution of the valve play in the model. From these tests, the distributions of velocity and vorticity of fluid in ＇various valves with different valve angles and different valve lifts are obtained, from which the features of flow fields are derived and generalized. Subsequently, a general rule of the influence of valve angles and valve lifts on the flow velocity is concluded according to chart analyses of maximal velocities and mean velocities. Finally, an analysis is made on the possibility of valve failure caused by erosion and abrasion in a working valve, with the application of the failure mechanisms of drilling pump valves. PIV measurement improves the study on the failure of the drilling pump valve, and the results show good agreement with previous computational fluid dynamics（CFD） simulations.展开更多
Dopaminergic neurons in the ventral tegmental area(VTA)play an important role in cognition,emergence from anesthesia,reward,and aversion,and their projection to the cortex is a crucial part of the"bottom-up"...Dopaminergic neurons in the ventral tegmental area(VTA)play an important role in cognition,emergence from anesthesia,reward,and aversion,and their projection to the cortex is a crucial part of the"bottom-up"ascending activating system.The prelimbic cortex(PrL)is one of the important projection regions of the VTA.However,the roles of dopaminergic neurons in the VTA and the VTADA–PrL pathway under sevoflurane anesthesia in rats remain unclear.In this study,we found that intraperitoneal injection and local microinjection of a dopamine D1 receptor agonist(Chloro-APB)into the PrL had an emergence-promoting effect on sevoflurane anesthesia in rats,while injection of a dopamine D1 receptor antagonist(SCH23390)deepened anesthesia.The results of chemogenetics combined with microinjection and optogenetics showed that activating the VTADA–PrL pathway prolonged the induction time and shortened the emergence time of anesthesia.These results demonstrate that the dopaminergic system in the VTA has an emergence-promoting effect and that the bottom-up VTADA–PrL pathway facilitates emergence from sevoflurane anesthesia.展开更多
BACKGROUND Anterior bone loss(ABL)is a relatively easily neglected condition after cervical disc replacement(CDR).Whether this phenomenon is a radiological anomaly or a complication remains controversial.Several studi...BACKGROUND Anterior bone loss(ABL)is a relatively easily neglected condition after cervical disc replacement(CDR).Whether this phenomenon is a radiological anomaly or a complication remains controversial.Several studies have reported the clinical characteristics of ABL and speculated on the pathogenic mechanism based on a certain type of artificial disc,while the overall understanding of ABL is lacking.AIM To describe the prevalence,impacts,and risk factors of ABL after CDR.METHODS We searched the PubMed,Cochrane Library,and Excerpta Medica databases using the terms“bone loss”or“bone remodeling”or“bone absorption”or“osteolysis”or“implant loosening”or“implant migration”or“hypersensitivity”or“hyperreactivity”,“cervical disc replacement”or“cervical disc arthroplasty”or“total disc replacement”.Eligible manuscripts on the prevalence and impacts of ABL were reviewed by the authors.Data extraction was performed using an established extraction form.The results of the included studies were described narratively.RESULTS Six studies met the inclusion and exclusion criteria.One was a prospective study and the others were retrospective studies.A total of 440 patients with 536 segments were included.The artificial cervical discs included Bryan,Baguera-C,Discocerv,and Mobi-C.The prevalence of ABL ranged from 3.13%to 91.89%,with a combined overall prevalence of 41.84%.ABL occurred within 6 mo and stopped 12 mo after surgery.Several cases were noted to have a self-healing process.Severe ABL resulted in segmental kyphosis,implant subsidence,and persistent neck pain.ABL may be related to heterotopic ossification.Multilevel surgery may be one of the risk factors for ABL.CONCLUSION ABL is a common condition after CDR.The underlying mechanisms of ABL may include stress concentration and injury to nutrient vessels.ABL should be considered a complication after CDR as it was associated with neck pain,implant subsidence,and heterotopic ossification.展开更多
Displacement monitoring in open-pit mines is one of the important tasks for safe management of mining processes.Differential interferometric synthetic aperture radar(DInSAR),mounted on an artificial satellite,has the ...Displacement monitoring in open-pit mines is one of the important tasks for safe management of mining processes.Differential interferometric synthetic aperture radar(DInSAR),mounted on an artificial satellite,has the potential to be a cost-effective method for monitoring surface displacements over extensive areas,such as open-pit mines.DInSAR requires the ground surface elevation data in the process of its analysis as a digital elevation model(DEM).However,since the topography of the ground surface in open-pit mines changes largely due to excavations,measurement errors can occur due to insufficient information on the elevation of mining areas.In this paper,effect of different elevation models on the accuracy of the displacement monitoring results by DInSAR is investigated at a limestone quarry.In addition,validity of the DInSAR results using an appropriate DEM is examined by comparing them with the results obtained by global positioning system(GPS)monitoring conducted for three years at the same limestone quarry.It is found that the uncertainty of DEMs induces large errors in the displacement monitoring results if the baseline length of the satellites between the master and the slave data is longer than a few hundred meters.Comparing the monitoring results of DInSAR and GPS,the root mean square error(RMSE)of the discrepancy between the two sets of results is less than 10 mm if an appropriate DEM,considering the excavation processes,is used.It is proven that DInSAR can be applied for monitoring the displacements of mine slopes with centimeter-level accuracy.展开更多
Automatic translation of Chinese text to Chinese Braille is important for blind people in China to acquire information using computers or smart phones. In this paper, a novel scheme of Chinese-Braille translation is p...Automatic translation of Chinese text to Chinese Braille is important for blind people in China to acquire information using computers or smart phones. In this paper, a novel scheme of Chinese-Braille translation is proposed. Under the scheme, a Braille word segmentation model based on statistical machine learning is trained on a Braille corpus, and Braille word segmentation is carried out using the statistical model directly without the stage of Chinese word segmentation. This method avoids establishing rules concerning syntactic and semantic information and uses statistical model to learn the rules stealthily and automatically. To further improve the performance, an algorithm of fusing the results of Chinese word segmentation and Braille word segmentation is also proposed. Our results show that the proposed method achieves accuracy of 92.81% for Braille word segmentation and considerably outperforms current approaches using the segmentation-merging scheme.展开更多
We intraperitoneally injected 10 and 50 mg/kg of propofol for 7 consecutive days to treat a rat model of chronic cerebral ischemia. A low-dose of propofol promoted the expression of brain-derived neurotrophic factor, ...We intraperitoneally injected 10 and 50 mg/kg of propofol for 7 consecutive days to treat a rat model of chronic cerebral ischemia. A low-dose of propofol promoted the expression of brain-derived neurotrophic factor, tyrosine kinase receptor B, phosphorylated cAMP response element binding protein, and cAMP in the hippocampus of aged rats with chronic cerebral ischemia, but a high-dose of propofol inhibited their expression. Results indicated that the protective effect of propofol against cerebral ischemia in aged rats is related to changes in the expression of brain-derived neurotrophic factor and tyrosine kinase receptor B in the hippocampus, and that the cAMP-cAMP responsive element binding protein pathway is involved in the regulatory effect of propofol on brain-derived neurotrophic factor expression.展开更多
We induced ischemic brain injury in aging rats to examine the effects of varying doses of propofol on hippocampal activities of acetylcholinesterase, N-methyI-D-aspartate receptors, and y-aminobutyric acid receptors. ...We induced ischemic brain injury in aging rats to examine the effects of varying doses of propofol on hippocampal activities of acetylcholinesterase, N-methyI-D-aspartate receptors, and y-aminobutyric acid receptors. Propofol exhibited no obvious impact on acetylcholinesterase activity, but directly activated the y-aminobutyric acid receptor. The neuroprotective function of propofol on the hippocampus of aging rats following cerebral ischemic injury may be related to altered activities of y-aminobutyric acid receptors and N-methyI-D-aspartate receptors.展开更多
文摘Objective: to explore the nursing safety and safeguard measures for patients undergoing daytime operation. Methods: a total of 30 daytime operation patients who received treatment in our hospital in recent years were selected as the research objects, and they were randomly and evenly divided into the research group and the control group, and then received routine nursing and nursing safety intervention respectively, and the nursing effects of the two groups of patients were compared and analyzed. Results: in practice, it was found that the occurrence rate of risk factors and delayed discharge rate of patients in the study group were lower than those in the control group. Conclusion: therefore, in the process of carrying out nursing work for patients undergoing daytime operation, strengthening nursing safety intervention can greatly improve the nursing work efficiency of patients undergoing operation.
文摘The Dimbokro health district has one of the highest incidences of malaria in Côte d’Ivoire, despite numerous campaigns to distribute Long-Acting Impregnated Mosquito Nets (LLINs). Given this observation, what are the population’s attitudes towards LLINs that could explain the high endemicity of malaria in Dimbokro? The aim of this study is to assess the knowledge, attitudes and practices of people in the health area of Nofou, one of the villages in the Dimbokro health district where malaria is most prevalent, with a view to strengthening malaria control strategies. A collection of historical health data (malaria cases and LLIN usage rates) and a cross-sectional questionnaire survey was carried out from July 20 to August 03, 2022 in 400 households selected by systematic random sampling. Data were entered using Epi Info 7 and multivariate statistical analyses were performed using IBM SPSS 22 software. In the Dimbokro health district, the rate of LLIN use was negatively correlated (r = -0.771) with malaria incidence over the six years of historical data collection. Households had an average of 53% good knowledge, 68.6% good practices and 28.4% good attitudes towards LLINs. The study also revealed that the main factors explaining LLIN use in the Nofou health area are mosquito bite (ORa = 5.29 (1.12 - 25.04)), age of household members (ORa = 1.07 (1.01 - 1.14)) and marital status (ORa = 8.45 (1.70 - 45.02)). Awareness-raising on the use of LLINs should be intensified in the Dimbokro health district. Other control strategies, such as vector control and environmental sanitation, should be considered to combat malaria.
基金supported by the Postdoctoral Fellow-ship Program of CPSF(Grant No.GZC20233105)the Science Foundation of China University of Petroleum,Beijing(Grant No.2462024XKBH006)+2 种基金the China Postdoctoral Science Foundation(Grant No.2024M753615)the Major Scientific Research Instrument Development Program of National Natural Science Foundation of China(Grant No.52227804)the Youth Science Foundation Program of National Natural Science Foundation of China(Grant No.52404012).
文摘The gas kick represents a major risk in deepwater oil and gas exploration.Understanding the dynamics of gas kick evolution and the associated pressure response characteristics is critical for effective well control.In this paper,we introduce a transient wellbore multiphase flow model specifically developed to simulate gas kick in deepwater dual-gradient drilling,incorporating a downhole separator.The model accounts for the variable mass flow within the annulus and heat exchange between the annular fluid and the formation.Using this model,we analyzed the multiphase flow and thermodynamic behavior during the gas kick.Simulation results reveal a progressive increase in bottom-hole temperature,underscoring its potential as a key indicator for gas kick early detection.Additionally,variable gradient parameters affect not only the annular equivalent circulating density(ECD)profile but also the evolution of the gas kick.The inclusion of a downhole separator alters the annular ECD profile,creating a“broken line”shape,which enhances adaptability to the multi-pressure systems typically encountered in deepwater forma-tion.By adjusting factors such as hollow sphere concentration,separator position,and separation effi-ciency,the annular ECD profile can be effectively customized.This study provides important theoretical insights and practical applications for utilizing dual-gradient drilling technology to address challenges in deepwater formation drilling.
基金supported by the National Key R&D Program of China(Grant No.2022YFA1005000)the National Natural Science Foundation of China(Grant No.62025110 and 62101308).
文摘Satellite Internet(SI)provides broadband access as a critical information infrastructure in 6G.However,with the integration of the terrestrial Internet,the influx of massive terrestrial traffic will bring significant threats to SI,among which DDoS attack will intensify the erosion of limited bandwidth resources.Therefore,this paper proposes a DDoS attack tracking scheme using a multi-round iterative Viterbi algorithm to achieve high-accuracy attack path reconstruction and fast internal source locking,protecting SI from the source.Firstly,to reduce communication overhead,the logarithmic representation of the traffic volume is added to the digests after modeling SI,generating the lightweight deviation degree to construct the observation probability matrix for the Viterbi algorithm.Secondly,the path node matrix is expanded to multi-index matrices in the Viterbi algorithm to store index information for all probability values,deriving the path with non-repeatability and maximum probability.Finally,multiple rounds of iterative Viterbi tracking are performed locally to track DDoS attack based on trimming tracking results.Simulation and experimental results show that the scheme can achieve 96.8%tracking accuracy of external and internal DDoS attack at 2.5 seconds,with the communication overhead at 268KB/s,effectively protecting the limited bandwidth resources of SI.
文摘Objective: To identify the principal factors associated with the occurrence and development of medical device-related pressure injuries (MDRPI) in adults admitted to hospitals. MDRPI, a peculiar subtype of pressure injuries (PI), result from the pression exerted by devices (or their fixation systems) applied for diagnostic and therapeutic purposes. MDRPI represent a serious problem for patients and healthcare systems. Understanding potential risk factors is an important step in implementing effective interventions. Methods: In this study, we will perform a systematic review;if possible, also a meta-analysis will be performed. The review will follow the preferred reporting items for systematic reviews and meta-analyses (PRISMA) reporting guidelines for systematic reviews. A rigorous literature search will be conducted both in electronic databases (Medline/PubMed, Embase, CINAHL, Web of Science, Scopus, Cochrane Library) to identify studies published since 2000 and in gray literature for unpublished studies. Pairs of researchers will identify relevant evidence, extract data, and assess risk of bias independently in each eligible study. Factors associated with the occurrence of MDRPI are considered the primary outcome. Secondary outcomes are prevalence and incidence of MDRPI, length of hospital stay, infections, and death. The evidence will be synthesized using the GRADE methodology. Results: Results are not currently available as this is a protocol for a systematic review. Conclusions: This systematic review will identify evidence on risk factors for developing MDRPI. We are confident that the results of this review will help to improve clinical practice and guide future research.
文摘While the significant role of technological innovation in promoting renewable energy has been extensively explored in the literature,limited attention has been paid to the impact of energy patents,particularly clean energy patents and fossil fuel patents.This study pioneers an investigation into the effects of energy patents and energy prices on renewable energy consumption.The study utilizes data from 2000Q1 to 2023Q4 and,due to the nonlinear nature of the series,applies wavelet quantile-based methods.Specifically,it introduces the wavelet quantile cointegration approach to evaluate cointegration across different quantiles and time horizons,along with the wavelet quantile-on-quantile regression method.The results confirm cointegration across different periods and quantiles,highlighting the significant relationships between energy patents,economic factors,and renewable energy consumption.Furthermore,we found that fossil energy patents negatively affect renewable energy consumption,while clean energy patents have a similar but weaker effect,especially in the short term.In addition,higher energy prices promote renewable energy adoption while economic growth positively influences renewable energy consumption,particularly in the short term.The study formulates specific policies based on these findings.
文摘In the leakage detection of reservoir dam bodies,traditional geophysical methods can only achieve one-time detection.Meanwhile,due to the non-uniqueness of geophysicalin version,how to improve the fidelity of geophysical detection inversion profiles has become a key challenge in the industry.This study aims to construct a long-term real-time monitoring system using the time-lapse resistivity method,reveal the spatiotemporal evolution law of dam leakage,and provide technical support for accurate treatment.By integrating the Internet of Things(IoT),5G technology,and AI technology,real-time data acquisition,real-time transmission,and automatic inversionare realized.Through dynamic imaging analysis of the electrical anomaly characteristics of the leakage area and comparison between corresponding rainfall events,the leakage range and resistivity changes,the reliability and efficiency of dam leakagedete ction are significantly improved.This achieves long-termdynamic monitoring of dam leakage and provides a new perspective for the safe operation and maintenance of reservoirs.
基金supported by the National Natural Science Foundation of China(Nos.U2033203,U1833126,61773203,61304190)。
文摘Air traffic flow management has been a major means for balancing air traffic demandand airport or airspace capacity to reduce congestion and flight delays.However,unpredictable fac-tors,such as weather and equipment malfunctions,can cause dynamic changes in airport and sectorcapacity,resulting in significant alterations to optimized flight schedules and the calculated pre-departure slots.Therefore,taking into account capacity uncertainties is essential to create a moreresilient flight schedule.This paper addresses the flight pre-departure sequencing issue and intro-duces a capacity uncertainty model for optimizing flight schedule at the airport network level.The goal of the model is to reduce the total cost of flight delays while increasing the robustnessof the optimized schedule.A chance-constrained model is developed to address the capacity uncer-tainty of airports and sectors,and the significance of airports and sectors in the airport network isconsidered when setting the violation probability.The performance of the model is evaluated usingreal flight data by comparing them with the results of the deterministic model.The development ofthe model based on the characteristics of this special optimization mechanism can significantlyenhance its performance in addressing the pre-departure flight scheduling problem at the airportnetwork level.
文摘As social interest in the environmental conservation and ecological restoration has recently increased, more research works have been done to resolve problems concerning environmental management of estuaries. In this study, a three-dimensional numerical model, Environmental Fluid Dynamics Code （EFDC） was used in the analysis of the salinity intrusion characteristics in the downstream of Geum River. The numerical simulation was performed to investigate the influence range for salinity intrusion when the gates were fully opened. The conditions used for simulation were the four flow regimes in Geum River Basin, Korea. Results indicated that the ranges of salinity intrusion from the barrage were 50.72 km （drought flow）, 48.87 km （low flow）, 46.56 km （normal flow） and 42.10 km （flood flow）. These results indicated that the EFDC model used for numerical simulation has high accuracy. The result concluded in this study can be used as a basis in understanding the extent of salinity intrusion effects at different flow rates.
基金supported by the NOAA (Grant Nos. NA16AOR4320115 and NA11OAR4320072)NSF (Grant No. AGS-1341878)
文摘After decades of research and development, the WSR-88 D(NEXRAD) network in the United States was upgraded with dual-polarization capability, providing polarimetric radar data(PRD) that have the potential to improve weather observations,quantification, forecasting, and warnings. The weather radar networks in China and other countries are also being upgraded with dual-polarization capability. Now, with radar polarimetry technology having matured, and PRD available both nationally and globally, it is important to understand the current status and future challenges and opportunities. The potential impact of PRD has been limited by their oftentimes subjective and empirical use. More importantly, the community has not begun to regularly derive from PRD the state parameters, such as water mixing ratios and number concentrations, used in numerical weather prediction(NWP) models.In this review, we summarize the current status of weather radar polarimetry, discuss the issues and limitations of PRD usage, and explore potential approaches to more efficiently use PRD for quantitative precipitation estimation and forecasting based on statistical retrieval with physical constraints where prior information is used and observation error is included. This approach aligns the observation-based retrievals favored by the radar meteorology community with the model-based analysis of the NWP community. We also examine the challenges and opportunities of polarimetric phased array radar research and development for future weather observation.
文摘To enable local water resource management and maintenance of ecosystem integrity and to protect and mitigate against flood and drought, it is necessary to determine changes in long-term series of streamflow and to distinguish the roles that climate change and human disturbance play in these changes. A review of previous research on the detection and attribution of observed changes in annual runoff in China shows a decrease in annual runoff since the 1950s in northern China in areas such as the Songhuajiang River water resources zone, the Liaohe River water resources zone, the Haihe River water resources zone, the Yellow River water resources zone, and the Huaihe River water resources Zone. Furthermore, abrupt changes in annual runoff occurred mostly in the 1970s and 1980s in all the above zones, except for some of the sub-basins in the middle Yellow River where abrupt change occurred in the 1990s. Changes in annual runoff are found to be mainly caused by climate change in the western Songhuajiang River basin, the upper mainstream of the Yangtze River, and the western Pearl River basin, which shows that studies on the impact of climate change on future water resources under different climate change scenarios are required to enable planning and management by agencies in these river basins. However, changes in annual runoff were found to be mainly caused by human activities in most of the catchments in northern China (such as the southern Songhuajiang River, Liaohe River, Haihe River, the lower reach and some of the catchments within the middle Yellow River basin) and in middle-eastern China, such as the Huaihe River and lower mainstream of the Yangtze River. This suggests that current hydro-climatic data can continue to be used in water-use planning and that policymakers need to focus on water resource management and protection.
基金We would like to acknowledge the efforts of the MGEX station operators,data,and analysis centers,as well as the ILRS for providing SLR normal points.
文摘The analysis centers of the Multi-GNSS Pilot Project of the International GNSS Service provide orbit and clock products for the global navigation satellite systems(GNSSs)Global Positioning System(GPS),GLONASS,Galileo,and BeiDou,as well as for the Japanese regional Quasi-Zenith Satellite System(QZSS).Due to improved solar radiation pressure modeling and other more sophisticated models,the consistency of these products has improved in recent years.The current orbit consistency between different analysis centers is on the level of a few centimeters for GPS,around one decimeter for GLONASS and Galileo,a few decimeters for BeiDou-2,and several decimeters for QZSS.The clock consistency is about 2 cm for GPS,5 cm for GLONASS and Galileo,and 10 cm for BeiDou-2.In terms of carrier phase modeling error for precise point positioning,the various products exhibit consistencies of 2–3 cm for GPS,6–14 cm for GLONASS,3–10 cm for Galileo,and 10–17 cm for BeiDou-2.
基金supported by National Natural Science Foundation of China (Grant No. 50575017, Grant No. 50875016)
文摘The failure of a drilling pump is always due to the break of the drilling pump valve, which is one of the most important but also the weakest parts of the drilling pump. Over the decades, the degradation of drilling pump valves has been investigated extensively and various failure mechanisms have been proposed. However, no experimental test on the fluid has been successfully performed to support some of these mechanisms. In this paper, tests of the flow within the valve play are carried out to investigate the factors resulting in the failure of the valve. In the tests, particle image velocimetry（PIV） technology is employed to measure the flow field distribution of the valve play in the model. From these tests, the distributions of velocity and vorticity of fluid in ＇various valves with different valve angles and different valve lifts are obtained, from which the features of flow fields are derived and generalized. Subsequently, a general rule of the influence of valve angles and valve lifts on the flow velocity is concluded according to chart analyses of maximal velocities and mean velocities. Finally, an analysis is made on the possibility of valve failure caused by erosion and abrasion in a working valve, with the application of the failure mechanisms of drilling pump valves. PIV measurement improves the study on the failure of the drilling pump valve, and the results show good agreement with previous computational fluid dynamics（CFD） simulations.
基金supported by the National Natural Science Foundation of China(81801366 and 82001453)and the National Key R&D Program of China(2018YFC2001901).
文摘Dopaminergic neurons in the ventral tegmental area(VTA)play an important role in cognition,emergence from anesthesia,reward,and aversion,and their projection to the cortex is a crucial part of the"bottom-up"ascending activating system.The prelimbic cortex(PrL)is one of the important projection regions of the VTA.However,the roles of dopaminergic neurons in the VTA and the VTADA–PrL pathway under sevoflurane anesthesia in rats remain unclear.In this study,we found that intraperitoneal injection and local microinjection of a dopamine D1 receptor agonist(Chloro-APB)into the PrL had an emergence-promoting effect on sevoflurane anesthesia in rats,while injection of a dopamine D1 receptor antagonist(SCH23390)deepened anesthesia.The results of chemogenetics combined with microinjection and optogenetics showed that activating the VTADA–PrL pathway prolonged the induction time and shortened the emergence time of anesthesia.These results demonstrate that the dopaminergic system in the VTA has an emergence-promoting effect and that the bottom-up VTADA–PrL pathway facilitates emergence from sevoflurane anesthesia.
基金Supported by West China Nursing Discipline Development Special Fund Project,Sichuan University,No.HXHL190161.3.5 Project for Disciplines of Excellence,West China Hospital,Sichuan University,No.ZYJC18029.
文摘BACKGROUND Anterior bone loss(ABL)is a relatively easily neglected condition after cervical disc replacement(CDR).Whether this phenomenon is a radiological anomaly or a complication remains controversial.Several studies have reported the clinical characteristics of ABL and speculated on the pathogenic mechanism based on a certain type of artificial disc,while the overall understanding of ABL is lacking.AIM To describe the prevalence,impacts,and risk factors of ABL after CDR.METHODS We searched the PubMed,Cochrane Library,and Excerpta Medica databases using the terms“bone loss”or“bone remodeling”or“bone absorption”or“osteolysis”or“implant loosening”or“implant migration”or“hypersensitivity”or“hyperreactivity”,“cervical disc replacement”or“cervical disc arthroplasty”or“total disc replacement”.Eligible manuscripts on the prevalence and impacts of ABL were reviewed by the authors.Data extraction was performed using an established extraction form.The results of the included studies were described narratively.RESULTS Six studies met the inclusion and exclusion criteria.One was a prospective study and the others were retrospective studies.A total of 440 patients with 536 segments were included.The artificial cervical discs included Bryan,Baguera-C,Discocerv,and Mobi-C.The prevalence of ABL ranged from 3.13%to 91.89%,with a combined overall prevalence of 41.84%.ABL occurred within 6 mo and stopped 12 mo after surgery.Several cases were noted to have a self-healing process.Severe ABL resulted in segmental kyphosis,implant subsidence,and persistent neck pain.ABL may be related to heterotopic ossification.Multilevel surgery may be one of the risk factors for ABL.CONCLUSION ABL is a common condition after CDR.The underlying mechanisms of ABL may include stress concentration and injury to nutrient vessels.ABL should be considered a complication after CDR as it was associated with neck pain,implant subsidence,and heterotopic ossification.
基金partially supported by JSPS KAKENHI(Grant No.16H03153)the Limestone Association of Japan。
文摘Displacement monitoring in open-pit mines is one of the important tasks for safe management of mining processes.Differential interferometric synthetic aperture radar(DInSAR),mounted on an artificial satellite,has the potential to be a cost-effective method for monitoring surface displacements over extensive areas,such as open-pit mines.DInSAR requires the ground surface elevation data in the process of its analysis as a digital elevation model(DEM).However,since the topography of the ground surface in open-pit mines changes largely due to excavations,measurement errors can occur due to insufficient information on the elevation of mining areas.In this paper,effect of different elevation models on the accuracy of the displacement monitoring results by DInSAR is investigated at a limestone quarry.In addition,validity of the DInSAR results using an appropriate DEM is examined by comparing them with the results obtained by global positioning system(GPS)monitoring conducted for three years at the same limestone quarry.It is found that the uncertainty of DEMs induces large errors in the displacement monitoring results if the baseline length of the satellites between the master and the slave data is longer than a few hundred meters.Comparing the monitoring results of DInSAR and GPS,the root mean square error(RMSE)of the discrepancy between the two sets of results is less than 10 mm if an appropriate DEM,considering the excavation processes,is used.It is proven that DInSAR can be applied for monitoring the displacements of mine slopes with centimeter-level accuracy.
基金Fthe National Key Technology R&D Program of China(No.2014BAK15B02)the National Natural Science Foundation of China(No.61202209)
文摘Automatic translation of Chinese text to Chinese Braille is important for blind people in China to acquire information using computers or smart phones. In this paper, a novel scheme of Chinese-Braille translation is proposed. Under the scheme, a Braille word segmentation model based on statistical machine learning is trained on a Braille corpus, and Braille word segmentation is carried out using the statistical model directly without the stage of Chinese word segmentation. This method avoids establishing rules concerning syntactic and semantic information and uses statistical model to learn the rules stealthily and automatically. To further improve the performance, an algorithm of fusing the results of Chinese word segmentation and Braille word segmentation is also proposed. Our results show that the proposed method achieves accuracy of 92.81% for Braille word segmentation and considerably outperforms current approaches using the segmentation-merging scheme.
基金supported by the National Natural Science Foundation of China (GABA receptor mechanism ofpropofol to promote neural regeneration), No. 30571791
文摘We intraperitoneally injected 10 and 50 mg/kg of propofol for 7 consecutive days to treat a rat model of chronic cerebral ischemia. A low-dose of propofol promoted the expression of brain-derived neurotrophic factor, tyrosine kinase receptor B, phosphorylated cAMP response element binding protein, and cAMP in the hippocampus of aged rats with chronic cerebral ischemia, but a high-dose of propofol inhibited their expression. Results indicated that the protective effect of propofol against cerebral ischemia in aged rats is related to changes in the expression of brain-derived neurotrophic factor and tyrosine kinase receptor B in the hippocampus, and that the cAMP-cAMP responsive element binding protein pathway is involved in the regulatory effect of propofol on brain-derived neurotrophic factor expression.
基金the General Program of National Natural Science Foundation of China,No.30571791
文摘We induced ischemic brain injury in aging rats to examine the effects of varying doses of propofol on hippocampal activities of acetylcholinesterase, N-methyI-D-aspartate receptors, and y-aminobutyric acid receptors. Propofol exhibited no obvious impact on acetylcholinesterase activity, but directly activated the y-aminobutyric acid receptor. The neuroprotective function of propofol on the hippocampus of aging rats following cerebral ischemic injury may be related to altered activities of y-aminobutyric acid receptors and N-methyI-D-aspartate receptors.
