MXenes,a unique class of two-dimensional(2D)transition metal carbides,nitrides,and carbonitrides,have garnered significant interest due to their exceptional chemical,mechanical,and electrical properties.While recent s...MXenes,a unique class of two-dimensional(2D)transition metal carbides,nitrides,and carbonitrides,have garnered significant interest due to their exceptional chemical,mechanical,and electrical properties.While recent studies predominantly focus on MXenes'applications in catalysis,energy storage and harvesting,photocatalysis,and lightweight materials,their potential in biomedicine is comparatively understated.This review aims to bridge this gap by providing a comprehensive and up-to-date overview of MXenes in biomedical applications,specifically highlighting advanced uses such as photothermal therapy and photodynamic therapy for cancer treatment,as well as their roles in biomedical imaging and as contrast agents for tumor visualization.We examine the synthesis and chemical modifications of MXenes,including functionalization,etching,and exfoliation techniques that enable tailored properties for biomedicine.This article highlights MXenes'advantages,including high surface area,tunable surface chemistry,and biocompatibility,while also addressing challenges and future research directions to unlock their full biomedical potential.This focused exploration of MXenes in cutting-edge biomedicine sets this review apart,highlighting its significance in advancing MXenes'role in modern biomedical research.展开更多
Recent advancements in hydrogel-based flexible materials have revolutionized wound healing and monitoring strategies.These materials offer promising solutions for medical treatment and real-time diagnostics.Their rich...Recent advancements in hydrogel-based flexible materials have revolutionized wound healing and monitoring strategies.These materials offer promising solutions for medical treatment and real-time diagnostics.Their rich water content,biocompatibility,and tunable properties closely mimic the natural extracellular matrix,supporting wound regeneration.Unlike traditional wound healing materials,hydrogel-based systems address critical issues such as material stability and toxicity while integrating advanced monitoring devices.This review highlights the latest innovations in hydrogel-based wound healing materials.It focuses on flexibility,biocompatibility,and potential for integration with smart monitoring systems.The review covers design principles and fabrication techniques for hydrogel-based nanofibers,elastomers,and conducting polymers.It also discusses the development of electronic skin and innovative wound dressings.In addition,the review explains how sensing capabilities,stimuli-responsive functions,and antibacterial agents are incorporated into these materials.Finally,the article examines challenges and future directions in the field.It emphasizes the transformative potential of multifunctional hydrogel-based materials for improving wound healing and continuous monitoring.展开更多
基金supported by the National Research Foundation of Korea(NRF)grant funded by the Korean Government(MSIT:2022R1A5A8023404)the 2024 Global Joint Research Program,funded by the Pukyong National University(202412210001)U.P.acknowledges VIEP,BUAP,for financial help extended through Grant(00262).
文摘MXenes,a unique class of two-dimensional(2D)transition metal carbides,nitrides,and carbonitrides,have garnered significant interest due to their exceptional chemical,mechanical,and electrical properties.While recent studies predominantly focus on MXenes'applications in catalysis,energy storage and harvesting,photocatalysis,and lightweight materials,their potential in biomedicine is comparatively understated.This review aims to bridge this gap by providing a comprehensive and up-to-date overview of MXenes in biomedical applications,specifically highlighting advanced uses such as photothermal therapy and photodynamic therapy for cancer treatment,as well as their roles in biomedical imaging and as contrast agents for tumor visualization.We examine the synthesis and chemical modifications of MXenes,including functionalization,etching,and exfoliation techniques that enable tailored properties for biomedicine.This article highlights MXenes'advantages,including high surface area,tunable surface chemistry,and biocompatibility,while also addressing challenges and future research directions to unlock their full biomedical potential.This focused exploration of MXenes in cutting-edge biomedicine sets this review apart,highlighting its significance in advancing MXenes'role in modern biomedical research.
基金supported by the National Research Foundation of Korea(NRF)grant funded by the Korean government(MSIT)(2022R1A5A8023404)the 2024 Global Joint Research Program,funded by the Pukyong National University(202412210001)U.P.acknowledges the support extended by VIEP-BUAP.
文摘Recent advancements in hydrogel-based flexible materials have revolutionized wound healing and monitoring strategies.These materials offer promising solutions for medical treatment and real-time diagnostics.Their rich water content,biocompatibility,and tunable properties closely mimic the natural extracellular matrix,supporting wound regeneration.Unlike traditional wound healing materials,hydrogel-based systems address critical issues such as material stability and toxicity while integrating advanced monitoring devices.This review highlights the latest innovations in hydrogel-based wound healing materials.It focuses on flexibility,biocompatibility,and potential for integration with smart monitoring systems.The review covers design principles and fabrication techniques for hydrogel-based nanofibers,elastomers,and conducting polymers.It also discusses the development of electronic skin and innovative wound dressings.In addition,the review explains how sensing capabilities,stimuli-responsive functions,and antibacterial agents are incorporated into these materials.Finally,the article examines challenges and future directions in the field.It emphasizes the transformative potential of multifunctional hydrogel-based materials for improving wound healing and continuous monitoring.
