Background and Objectives:Type 2 diabetes mellitus(T2DM)has emerged as a significant global public health concern.Multiple studies have shown that traditional nutraceuticals are potential to treat T2DM and its complic...Background and Objectives:Type 2 diabetes mellitus(T2DM)has emerged as a significant global public health concern.Multiple studies have shown that traditional nutraceuticals are potential to treat T2DM and its complications.This review will explore traditional nutraceuticals with antidiabetic properties with a focus on traditional Asian nutraceuticals and their antioxidant effects on gene expression associated to T2DM.Methods and Study Design:Literature searching was conducted in Pubmed,Scopus,and Science Direct using the keywords“nutraceutical”,“antidiabetic”,“insulin resistance”,“Diabetes Mellitus”,“herbal medicine”,“mechanism”,“pathway”,“traditional food”,“functional food”,“antioxidant”,“clinical”,“preclinical”,“animal studies”,and“Asian”combined with Boolean operators“OR”.Results:Nutraceuticals sourced from traditional Indonesian herbal beverages,including Galohgor,Bir Pletok,and Wedang Uwuh,have shown potential efficacy in reducing hyperglycemia,oxidative stress,and obesity in T2DM.展开更多
基金supported by Ministry of Education,Culture,Research,and Technology,Republic of Indonesia under the Regular Fundamental Research Grant[Grant No.22049/IT3.D10/PT.01.03/P/B/2024]。
文摘Background and Objectives:Type 2 diabetes mellitus(T2DM)has emerged as a significant global public health concern.Multiple studies have shown that traditional nutraceuticals are potential to treat T2DM and its complications.This review will explore traditional nutraceuticals with antidiabetic properties with a focus on traditional Asian nutraceuticals and their antioxidant effects on gene expression associated to T2DM.Methods and Study Design:Literature searching was conducted in Pubmed,Scopus,and Science Direct using the keywords“nutraceutical”,“antidiabetic”,“insulin resistance”,“Diabetes Mellitus”,“herbal medicine”,“mechanism”,“pathway”,“traditional food”,“functional food”,“antioxidant”,“clinical”,“preclinical”,“animal studies”,and“Asian”combined with Boolean operators“OR”.Results:Nutraceuticals sourced from traditional Indonesian herbal beverages,including Galohgor,Bir Pletok,and Wedang Uwuh,have shown potential efficacy in reducing hyperglycemia,oxidative stress,and obesity in T2DM.
