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Identification of the preferentially targeted proteins by carbamylation during whole lens incubation by using radio-labelled potassium cyanate and mass spectrometry 被引量:3
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作者 John J Harding 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2010年第2期104-111,共8页
AIMTo attempt to identify the primary targets of carbamylation in bovine lenses incubated under physiological condition.
关键词 CARBAMYLATION CYANATE cataract IDENTIFICATION LENS mass spectrometry post-translational modification ξ-crystallin
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METIPRANOLOL IS NEUROPROTECTIVE IN RETINAL ISCHAEMIA
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作者 K.G.Schmidt N.N.Osborne +2 位作者 J.Melena J.P.M.Wood L.Pillunat 《国际眼科杂志》 CAS 2003年第1期48-48,共1页
Purpose: To investigate whether the mixed beta-blocker, metipranolol, possesses calcium and sodium channel blocking activities and blunts the effects of retinal ischaemia as reported for the betal-antagonist, betaxolo... Purpose: To investigate whether the mixed beta-blocker, metipranolol, possesses calcium and sodium channel blocking activities and blunts the effects of retinal ischaemia as reported for the betal-antagonist, betaxolol (Expt. Eye Research 1999, 69, 331-342). Methods: Rat retinas or rat brain synaptosomes were exposed to radioactive calcium or sodium and NM- 展开更多
关键词 视网网缺血 Β-阻滞剂 钙通道 美替洛尔 神经保护作用
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