Identification of the glymphatic system,defined as a perivascular network that facilitates the clearance of metabolic waste through the exchange of cerebrospinal fluid(CSF)and interstitial fluid(ISF),has reshaped pers...Identification of the glymphatic system,defined as a perivascular network that facilitates the clearance of metabolic waste through the exchange of cerebrospinal fluid(CSF)and interstitial fluid(ISF),has reshaped perspectives on cerebral homeostasis and its implications for health and disease[1].According to the Global Burden of Disease Study 2019,psychiatric disorders accounted for approximately 4.9%of global disability-adjusted life years[2],highlighting the urgent need for targeted interventions.展开更多
基金supported by the STI2030-Major Projects(2021ZD0200800)the National Natural Science Foundation of China(82288101)Joint Innovation Team for Clinical&Basic Research of Shandong First Medical University(202404).
文摘Identification of the glymphatic system,defined as a perivascular network that facilitates the clearance of metabolic waste through the exchange of cerebrospinal fluid(CSF)and interstitial fluid(ISF),has reshaped perspectives on cerebral homeostasis and its implications for health and disease[1].According to the Global Burden of Disease Study 2019,psychiatric disorders accounted for approximately 4.9%of global disability-adjusted life years[2],highlighting the urgent need for targeted interventions.
