Dear Editor,Lung cancer(LC)is the leading cause of cancer mortality globally,accounting for more than 1.7 million deaths per year[1].There is consensus that LC screening needs to target those at high risk who are most...Dear Editor,Lung cancer(LC)is the leading cause of cancer mortality globally,accounting for more than 1.7 million deaths per year[1].There is consensus that LC screening needs to target those at high risk who are most likely to benefit from screening in order to maximize benefits and minimize potential harms.Given the key role of smoking in determining LC risk[2],most of the low-dose computed tomography(LDCT)screening trials have defined heavy smoking as an eligibility criterion for LC screening[3].Although LDCT screening has been effective in reducing LC mortality[4,5].展开更多
Dear editor,Lung cancer(LC)is the leading cause of cancer-related mortality globally[1].Earlier detection by screening can substantially reduce LC mortality[2,3],but should be focused on those at highest risk[4].Risk ...Dear editor,Lung cancer(LC)is the leading cause of cancer-related mortality globally[1].Earlier detection by screening can substantially reduce LC mortality[2,3],but should be focused on those at highest risk[4].Risk stratification for LC screening,which is mostly based on smoking history[5],is far from perfect[6].Therefore,additional criteria to better define those at highest risk of LC are needed to enhance the efficiency and cost-effectiveness of LC screening.Besides risk prediction models incorporating classical LC risk factors[7].展开更多
文摘Dear Editor,Lung cancer(LC)is the leading cause of cancer mortality globally,accounting for more than 1.7 million deaths per year[1].There is consensus that LC screening needs to target those at high risk who are most likely to benefit from screening in order to maximize benefits and minimize potential harms.Given the key role of smoking in determining LC risk[2],most of the low-dose computed tomography(LDCT)screening trials have defined heavy smoking as an eligibility criterion for LC screening[3].Although LDCT screening has been effective in reducing LC mortality[4,5].
文摘Dear editor,Lung cancer(LC)is the leading cause of cancer-related mortality globally[1].Earlier detection by screening can substantially reduce LC mortality[2,3],but should be focused on those at highest risk[4].Risk stratification for LC screening,which is mostly based on smoking history[5],is far from perfect[6].Therefore,additional criteria to better define those at highest risk of LC are needed to enhance the efficiency and cost-effectiveness of LC screening.Besides risk prediction models incorporating classical LC risk factors[7].
