In this study we review the occurrence of different types (A, B, C, M, and X classes) of solar flares during different solar cycle phases from 1996 to 2019 covering the solar cycles 23 and 24. During this period, a to...In this study we review the occurrence of different types (A, B, C, M, and X classes) of solar flares during different solar cycle phases from 1996 to 2019 covering the solar cycles 23 and 24. During this period, a total of 19,126 solar flares were observed regardless the class: 3548 flares in solar cycle 23 (SC23) and 15,668 flares in solar cycle 24 (SC24). Our findings show that the cycle 23 has observed the highest occurrences of M-class and X-class flares, whereas cycle 24 has pointed out a predominance of B-class and C-class flares throughout its different phases. The results indicate that the cycle 23 was magnetically more intense than cycle 24, leading to more powerful solar flares and more frequent geomagnetic storms, capable of generating significant electromagnetic emissions that can affect satellites and GPS signals. The decrease in intense solar flares during cycle 24 compared to cycle 23 reflects an evolution in solar activity patterns over time.展开更多
Staphylococcus aureus (S. aureus) is a bacterial pathogen for humans and animals. These bacteria can resist against many antibiotics and this resistance constitute an alarming worldwide human health threat due to the ...Staphylococcus aureus (S. aureus) is a bacterial pathogen for humans and animals. These bacteria can resist against many antibiotics and this resistance constitute an alarming worldwide human health threat due to the morbidity and mortality. Phage therapy is one of the alternative treatments. The aim of this study was to isolate and characterize lytic phages of S. aureus from different wastewater sources in Bobo-Dioulasso, Burkina Faso. Eight strains of S. aureus were isolated from different clinical samples and were used to isolate phages. The isolation and host range of phages were done by the spot test. Phages were purified by the double-layer method. Similar phages after the determination of the host range were characterized using restriction enzymes. A total of 27 phages were obtained after isolation and purification. Nine of the 27 isolates reported a broad host range (≥67%). The results of enzymatic digestion allowed to consider that all phage isolates that presented the same host range and the same genetic fingerprint are the same phage strain;whereas phages that presented the same host range and different genetic fingerprints are different phage strains. Thus, a total of 15 distinct phages isolates specific to S. aureus were characterized. This study highlighted the abundance and lytic capacity of phages isolated from wastewater from Bobo-Dioulasso’s environment against clinical strains of S. aureus. The lytic capacity of these Staphyphages could be an effective alternative tool to combat bacteria multi-resistance.展开更多
In this study, we examined variability of sun-related energies, auroral electrojet current, ring current, and magnetopause current during solar cycles 23 and 24. The study revealed a dependence of sun-related energies...In this study, we examined variability of sun-related energies, auroral electrojet current, ring current, and magnetopause current during solar cycles 23 and 24. The study revealed a dependence of sun-related energies to the Sun and Earth currents systems with solar activity from 1996 to 2019. A decrease in the correlation between sun-related energies and sunspot number was observed over solar cycles 23 and 24 (0.88 for the solar cycle 23 and 0.66 for the solar cycle 24), with a drop in the speed of magnetic disturbances in the solar wind. These results could be attributed to the decrease in Sun’s magnetic field toroidal component magnitude induced by a weak in sunspots number and solar flares during the solar cycle 24. A weak in the Earth currents systems (auroral electrojet current, ring current, and magnetopause current) is also observed. During the decrease in the Earth currents, several peaks are observed, indicating a nonlinear dependence in the Earth currents variation (ring current, auroral electrojet current, and magnetopause current) from solar cycle 23 to solar cycle 24. This could be attributed to the Corotating Interaction Regions (CIRs) observed during the declining phase of solar cycle 23 and the deep minimum preceding solar cycle 24.展开更多
One of the most promising vector control strategies for controlling dengue fever is the stable introduction of the obligate intracellular Wolbachia bacteria strain into Aedes aegypti mosquitoes. This method reduces th...One of the most promising vector control strategies for controlling dengue fever is the stable introduction of the obligate intracellular Wolbachia bacteria strain into Aedes aegypti mosquitoes. This method reduces the mosquito’s ability to transmit dengue through reproductive strategies associated with Wolbachia infection, such as parthenogenesis, male elimination or feminization, sex ratio distortions and cytoplasmic incompatibility. Expert knowledge and a risk assessment framework were used to identify the risks associated with the release of Wolbachia-bearing mosquitoes. Then, consultations with individual participants were organized and a Bayesian network (BN) was developed to capture the relationship between the hazards as well as the likelihood of these adverse events occurring. Finally, risk was calculated from the probability and consequence estimates obtained from our Burkina Faso participants, using a questionnaire based on the identified risks. Our “Cause More Harm” study yielded 46.15% negligible risk, 44.23% very low risk and 9.62% low risk. The “socio-cultural change” parameter had the greatest influence, with the perception that the dissemination project would be poorly received by the local population. This parameter alone accounted for 80% of the most significant risks. This explains the fact that hazard RA 49 “negative messages in social media” is ranked as the highest individual risk (although the risk is low) with a calculated risk of 0.261. The risk assessment was designed to integrate the interdependent complexity of hazards likely to affect the dissemination of technology in the environment. It represents an important implementation phase in the success of this innovative research, introducing a new technology to combat the transmission of dengue fever.展开更多
In Burkina Faso, as in other African countries, infertility has become a social burden for the population and a public health problem. Male infertility accounts for 30% to 40% of all infertility cases. The diagnosis o...In Burkina Faso, as in other African countries, infertility has become a social burden for the population and a public health problem. Male infertility accounts for 30% to 40% of all infertility cases. The diagnosis of male infertility or hypofertility is often made by a simple laboratory analysis of sperm to explore sperm parameters. In most African countries, such as Burkina Faso, microbiological analysis in the context of sperm analysis is still not developed, and is carried out solely based on microscopy and traditional culture, which does not allow the growth of fragile and demanding bacteria. Our study investigated the microorganisms of sperm that may be involved in male infertility, using conventional bacteriology techniques and real-time PCR. However, it did not intend to perform a multivariate statistical association analysis to estimate the association of microorganisms with abnormal semen parameters. This prospective cross-sectional pilot study was carried out on patients who visited the bacteriology laboratory of Centre MURAZ, a research Institute in Burkina Faso, for male infertility diagnosis between 2 August and 31 August 2021. Bacteria were isolated and identified using standard bacteriology techniques. In parallel, common pathogenic microorganisms known to be associated with male infertility were targeted and detected in the sperm using a multiplex real-time PCR assay. A total of 38 sperm samples were analyzed by bacteriological culture and bacteria isolated were Staphylococcus aureus (S. aureus) 5.55%, Klebsiella pneumoniae (K. pneumoniae), Enterococcus faecalis (E. faecalis), Streptococcus agalactiae (S. agalactiae) and Staphylococcus hoemalyticus (S. hoemalyticus) respectively 2.70%. Real-time PCR targeted and detected Chlamydia trachomatis (C. trachomatis) at 7.89%, Ureaplasma urealyticum (U. urealyticum) at 21.05%, Ureaplasma parvum (U. parvum) at 18.42%, Mycoplasma hominis (M. hominis) at 15.79%, Mycoplasma genitalium (M. genitalium) at 10.53% and Trichomonas vaginalis (T. vaginalis) at 2.63%. Neisseria gonorrhoeae (N. gonorrhoeae) was targeted by the real-time PCR assay and was not detected (0%) in the tested semen samples. Our study highlights critical limitations of culture performance (low sensitivity), particularly in Burkina Faso, which has a total inability to detect microorganisms (fragile and demanding microorganisms) detected by PCR-based assays. There is therefore an urgent need to at least optimize culture, procedures and algorithms for detection of microorganisms associated with male infertility in clinical laboratories of Burkina Faso. The most effective solution is the routine implementation of molecular diagnostic methods.展开更多
Antimicrobial resistance (AMR) is one of the top 10 threats to global health and it is estimated around 10 millions of deaths per year are associated with AMR until 2050. Burkina Faso is also facing the emergence and ...Antimicrobial resistance (AMR) is one of the top 10 threats to global health and it is estimated around 10 millions of deaths per year are associated with AMR until 2050. Burkina Faso is also facing the emergence and spread of AMR of several bacteria resistant strains such as those of public health concerns under surveillance Enterobacteriaceae. The aim of this study was to assess the prevalence of extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBL-PE) clinical isolates from patients attending the bacteriology laboratory of the Centre MURAZ in Bobo-Dioulasso, Burkina Faso. Clinical isolates from urine, pus, stool, and semen were collected from April to June 2017. Identification and antibiotic susceptibility testing were performed using the VITEK 2 compact automated system according to EUCAST version 2015 recommendations. ESBL detection was then performed on the Muller-Hinton medium using the combined disc method. One hundred (100) strains of Enterobacteriaceae were isolated from 100 patients, including 52% of ESBLS. Escherichia coli (E. coli) was the most commonly isolated ESBL [(84.62, 44/72) ESBL], followed by Klebsiella spp. [(40%, 06/15) ESBL], then Enterobacter spp. [(40%, 2/5) ESBL]. Risk factor analysis revealed that ESBL-PE infection was frequently found in pus samples (P = 0.042;[OR] = 3.16;95% [CI] = 1.04 - 9.61) and that E. coli was the strain most likely to harbour ESBL (P = 0.008;[OR] = 3.60;95% [CI] = 1.40 - 9.31). This study reports a high prevalence of ESBL-PE associated with strong resistance to quinolones and cotrimoxazole (over 80%), which calls for increased surveillance of these superbugs, the adoption of a rational antibiotic prescription policy, and rigorous hygiene measures to prevent the spread of these multi-resistant bacteria.展开更多
This study examines the influence of magnetic field and temperature on the transient voltage of a polycrystalline silicon radial junction solar cell in a dynamic regime under multispectral illumination. Radial junctio...This study examines the influence of magnetic field and temperature on the transient voltage of a polycrystalline silicon radial junction solar cell in a dynamic regime under multispectral illumination. Radial junction solar cells represent a major advancement in photovoltaic technologies, as they optimize light absorption and charge collection efficiency. The focus is on the impact of the magnetic field and temperature on the decay of transient voltage, which provides crucial information on recombination processes and the lifetime of minority carriers. The results reveal that the magnetic field tends to increase the transient voltage by directly affecting the transient electron density. Indeed, for B > 7 × 10−5 T, the magnetic field prolongs the relaxation time by increasing the transient voltage amplitude. Additionally, rising temperatures accelerate (ranging from 290 K to 450 K) recombination processes, thereby reducing the transient voltage, although this effect is moderated by the presence of a magnetic field. The study highlights the complex interaction between magnetic field and temperature, with significant impacts on the transient behaviour.展开更多
In Burkina Faso, recent dengue outbreaks were exacerbated by Aedes aegypti mosquitoes, which have developed resistance to conventional insecticides. This study investigates the potential of Metarhizium pingshaense Met...In Burkina Faso, recent dengue outbreaks were exacerbated by Aedes aegypti mosquitoes, which have developed resistance to conventional insecticides. This study investigates the potential of Metarhizium pingshaense Met_S26, a fungus from Burkina Faso, for controlling both endophilic and exophilic Aedes mosquitoes. Traditional interventions are less effective against mosquitoes resting outdoors, and the ability of the fungus to be sexually transmitted could enhance its efficacy. Aedes mosquitoes were reared and exposed to various concentrations of Metarhizium pingshaense to assess its virulence. The fungus showed significant efficacy, with lethal times (LT80) ranging from 8.67 to 11.83 days depending on the concentration. Furthermore, bioassays demonstrated effective sexual auto-dissemination, with substantial transmission of fungal spores between infected and uninfected mosquitoes, leading to lower survival rates in uninfected mates. This study highlights Metarhizium pingshaense Met_S26 as a promising tool for controlling both indoor and outdoor Aedes populations, complementing existing vector control strategies such as the Sterile Insect Technique (SIT) and Wolbachia-based approaches. Future research should explore integrating this fungus with other control methods for a comprehensive vector management strategy.展开更多
Over the last few decades, dengue fever epidemics have increased in frequency and intensity worldwide, making it a major global concern for public health. Its prevention, which is essentially vector-based control, is ...Over the last few decades, dengue fever epidemics have increased in frequency and intensity worldwide, making it a major global concern for public health. Its prevention, which is essentially vector-based control, is already being compromised by reports of resistance of the main vector Aedes aegypti to insecticides. To tackle the rapid increase in insecticide resistance and outbreaks, the biological vector control is a promising approach. One of the strategies of this approach is the use of entomopathogenic fungi because of their great efficacy and their eco-friendly aspects. However, some aspects of their use, such as the low efficiency, the high cost of production and the sensitivity to various adverse conditions, need to be addressed for their successful large-scale application. Therefore, innovative technologies based on strains of transgenic fungi with improved biocontrol potentials by genetic engineering are actively pursued. Although these modified mycoinsecticides are acclaimed for their better effectiveness against target insects, the main concern remains their potential adverse effects on the environment and human health. The present review is dedicated to giving an update on recent developments in transgenic entomopathogenic fungi (TEF) for Aedes mosquito control. Future perspectives are also proposed to address the safety concerns related to the release of transgenic entomopathogenic fungi into the environment.展开更多
Migration is a complex demographic phenomenon.Its dynamics can be explained by several factors whose spatial and temporal evolution is not easy to control.That is why this article aims to understand the factors of mig...Migration is a complex demographic phenomenon.Its dynamics can be explained by several factors whose spatial and temporal evolution is not easy to control.That is why this article aims to understand the factors of migration from a spatiotemporal perspective to fill the gaps in the literature.The aim of this article is to analyse the spatiotemporal dynamics of internal migration factors to deduce the zones of origin and destination in Burkina Faso.To do this,several types of data were used.These included secondary,spatial,statistical and survey data.The results of this study show that the influence of internal migration factors is uneven.The spatial distribution of internal migration factors follows a north-south gradient,with favourable conditions in the south.In fact,the northern part is characterised by a large population exodus,with around 42.6%of outgoing internal migrants,and the southern part by a large population influx.This southern part of the country receives around 34.6%of internal migrants.The areas from which migrants depart have unfavourable climatic,environmental,or socio-economic conditions,whereas the areas to which migrants migrate are characterised by favourable conditions for these factors.展开更多
Sexually transmitted infections (STIs) represent a public health problem due to their high prevalence worldwide and the emergence of multidrug resistance of responsible microorganisms. Medical laboratory diagnosis of ...Sexually transmitted infections (STIs) represent a public health problem due to their high prevalence worldwide and the emergence of multidrug resistance of responsible microorganisms. Medical laboratory diagnosis of sexually transmitted genital infections by traditional methods as culture remains extremely delicate, difficult or impossible (to find extremely fragile organisms that can be cultured). Thus, molecular techniques constitute an alternative to improve accurate diagnostic, personalized patient treatment, and public health. A total of 83 clinical samples including urethral discharge and urine samples from individual patients with symptoms of urethritis received were analyzed using traditional methods and a commercial real-time PCR (qPCR) method. Out of 83 urethritis patients, n = 55 (66.26%) were positive for at least one of the STI pathogens detected by qPCR. qPCR assay was more sensitive (50/83, positive cases) compared to culture (15/83, positive cases) and light microscopy (28/83, positive cases). The most prevalent NTD pathogen in the suspected patients was N. gonorrhoeae with 60.24% (50/83) based on real-time PCR diagnosis. Among the positive cases of STI pathogens, Neisseria gonorrhoeae had the highest frequency 49/55 (89.01%) followed by low frequencies of Trichomonas vaginalis 4/55 (7.27%) and Chlamydia trachomatis 1/55 (1.82%). This highlights the high prevalence of N. gonorrhoeae infection in male urethritis patients and a very important misdiagnosis using traditional routine methods in Burkina Faso by medical laboratories. Thus, this situation may negatively impact patients’ personalized treatment and care and public health with the possible rapid emergence of multidrug-resistant strains. This study also highlights the urgent need to optimize culture for the diagnosis of NTD pathogens in Burkina Faso and the usefulness and the need for the introduction of molecular diagnostic methods in routine diagnosis for the detection of NTD pathogens in the medical laboratories in Burkina Faso.展开更多
This review explores the research activities surrounding the development and integration of smart electricity grids in Burkina Faso, a landlocked and arid territory in West Africa and one of the poorest countries in t...This review explores the research activities surrounding the development and integration of smart electricity grids in Burkina Faso, a landlocked and arid territory in West Africa and one of the poorest countries in the world with significant energy challenges. It examines the current state of energy infrastructure in Burkina Faso, focusing on the integration of renewable energy sources, particularly solar photovoltaics. It highlights the role of smart grid technologies in enabling the efficient integration of renewable energy, improving grid stability and facilitating rural electrification. Additionally, the review addresses key challenges such as inadequate infrastructure, regulatory gaps and financial constraints that hinder the deployment of smart grids in the country. By analysing existing research and ongoing projects, this paper provides a comprehensive overview of the opportunities and barriers to implementing a smart electricity grid in Burkina Faso and offers recommendations for future development and policy frameworks.展开更多
Malaria is a potentially lethal disease caused by parasites of the Plasmodium genus, transmitted to humans through the bite of infected female mosquitoes, primarily Anopheles. To control this disease, various strategi...Malaria is a potentially lethal disease caused by parasites of the Plasmodium genus, transmitted to humans through the bite of infected female mosquitoes, primarily Anopheles. To control this disease, various strategies are implemented, including biological control, which targets the vectors of the parasite. This approach uses biological agents such as entomopathogenic fungi, including Metarhizium pingshaense, a fungus capable of causing lethal infections in mosquitoes. The production of Metarhizium pingshaense is still limited in Burkina Faso, and local cultivation of this fungus could help fill this gap. A study was conducted to identify optimal local substrates that promote its growth. Indeed, after gathering information on the dietary habits of populations in Bobo-Dioulasso and Bama, three potential substrates were selected: rice, cornmeal dough (MFL), and beans. These substrates were inoculated with two strains of Metarhizium pingshaense (S10 and S26) to assess their ability to support fungal growth and their effectiveness. Experimental results showed that MFL and bean substrates favored optimal growth of Metarhizium pingshaense, with growths of 1.91 cm and 2.13 cm after 8 days, compared to 1.83 cm on a standard media (PDA). In terms of virulence, S26 strain caused 60% mosquito mortality on both the bean and PDA media, while S10 strain induced mortalities of 50% for bean and 62% for PDA.展开更多
Introduction: Arbovirus diseases such as dengue and chikungunya threaten public health worldwide. Early and rapid diagnosis and surveillance of dengue virus (DENV) and chikungunya virus (CHIKV) infections are essentia...Introduction: Arbovirus diseases such as dengue and chikungunya threaten public health worldwide. Early and rapid diagnosis and surveillance of dengue virus (DENV) and chikungunya virus (CHIKV) infections are essential to the control of these diseases. In this study, we evaluate the diagnostic performance of our new in-house multiplex RT-qPCR method for detecting DENV serotypes and CHIKV in an external laboratory. Methodology: The evaluation study was conducted on 200 clinical samples of suspected patients for arbovirus disease infection, collected in Centre de Recherche Biomoléculaire Pietro Annigoni (CERBA), Ouagadougou, Burkina Faso. Our new multiplex RT-qPCR was compared to the commercial kit, the Zika, Dengue, and Chikungunya (ZDC) Real-Time PCR Assays kit (Bio-Rad, California, USA). Results and Conclusions: Among 200 samples, 21.5% (43/200) were DENV-positive by multiplex RT-qPCR, and 21.5% (43/200) were also DENV-positive by reference real-time RT-PCR. 157 (78.5%) samples tested negative for DENV by both tests (new mRT-qPCR and reference test). The sensitivity and specificity of mRT-qPCR were 100%. The DENV serotypes detected were DENV-1 60.5% (26/43) and DENV-3 39.5% (17/43). CHIKV was not detected in this study. Our new mRT-qPCR is sensitive, cost-effective, simple, and can be used in developing country laboratories.展开更多
Introduction: A recent study in Kenya highlighted a promising advance in malaria control by demonstrating that infecting mosquitoes with the endosymbiont Microsporidia MB blocks Plasmodium transmission. However, the i...Introduction: A recent study in Kenya highlighted a promising advance in malaria control by demonstrating that infecting mosquitoes with the endosymbiont Microsporidia MB blocks Plasmodium transmission. However, the influence of biotic and abiotic factors such as diet, relative humidity (RH) and temperature on this infection remains poorly studied. This study, aimed to gain a better understanding of this relationship. Methods: To highlight the influence of diet quantity, we defined a range of 3 quantities: 0.00375 g, 0.015 g and 0.09 g. Each quantity was tested on two groups of larvae: a group of 150 larvae infected with Microsporidia MB (MB+), and a group of 150 larvae not infected with Microsporidia MB (MB−) (control group), each divided into three replicates of 50 larvae. Each replicate was fed each morning with the assigned quantity until the pupal stage. In addition to this factor, we investigated the influence of temperature and RH. We defined three temperature-RH combinations: 21˚C-80% RH, 39˚C-50% RH, and 27˚C-75% RH. Each combination was tested on two groups of larvae: a group of 150 MB+ larvae and a group of 150 MB− larvae, each divided into three replicates of 50 larvae. Each replicate was subjected to the assigned combination until pupation. Pupae that had reached the adult stage were tested by PCR to determine their Microsporidia MB infection status for each factor studied. Results: The results showed that only the lowest quantity (0.00375 g) significantly reduced the prevalence of Microsporidia MB compared with the medium quantity (chi-2 test, χ2 = 4.9088, df = 1, p = 0.02672) and the high quantity (chi-2 test, χ2 = 4.7958, df = 1, p = 0.02853). As for temperature and RH, the combination 39˚C-50% RH led to a significant reduction in the prevalence of Microsporidia MB compared with the combination 27˚C-75% RH (chi-2 test, χ2 = 6.3736, ddl = 1, p = 0.01158) and that 21˚C-80% RH (chi-2 test, χ2 = 9.983, ddl = 1, p = 0.00158). Conclusion: This work contributes to a better understanding of some key factors linked to Microsporidia MB infection in mosquitoes. However, further research on several generations is necessary to draw more comprehensive conclusions.展开更多
Background: According to the World Health Organization, the worldwide prevalence of infertility is 17.5%. The male share of responsibility is undeniable. Several factors, such as smoking, alcoholism, obesity and envir...Background: According to the World Health Organization, the worldwide prevalence of infertility is 17.5%. The male share of responsibility is undeniable. Several factors, such as smoking, alcoholism, obesity and environmental pollution are sources of infertility in men. The aim of this study was to determine the spermological profile of infertile men and the factors associated with sperm parameter abnormalities. Methods: This retrospective study analysed 1000 sperm samples over an 11-year period, from January 2010 to December 2021. Results: The average age was 37.52 ± 8.66 years. Surgical history of varicocele and teratozoospermia were associated (p-value = 0.0001). Candida albicans was associated with a 2.27-fold risk of necrozoospermia and a 3.14-fold risk of oligozoospermia. The link between the reason for requesting a spermogram and the age range between 38 and 47 was significant (p-value Conclusion: Today, lifestyle and environmental pollution play a major role in sperm parameter abnormalities.展开更多
In this paper we report on the foF2 variabilities for two equatorial regions (Ouagadougou: Lat. 12.4°N;Long. 358.5°E, Dip. 1.43°S;and Manila: Lat. 14°36'15.12''N;Long. 120°58'5...In this paper we report on the foF2 variabilities for two equatorial regions (Ouagadougou: Lat. 12.4°N;Long. 358.5°E, Dip. 1.43°S;and Manila: Lat. 14°36'15.12''N;Long. 120°58'55.92''E;Dip. 0.6°S) during solar cycles 20 and 21 minima and maxima phases. Many previous works have argued on the diurnal and seasonal variation of foF2 for different solar events conditions for latitudinal position. But there are few investigations for Africa equatorial region longitudinal variation. The present paper’s goal is to outline possible similarity in foF2 behavior between variations for better understanding of physical process lead to some observed phenomenon in Asia-Africa equatorial sector. The F-layer critical frequency (foF2) data observed from the two equatorial ionosonde stations have been used for the present comparative study. The results show significant similarity between the critical frequency (foF2) seasonal variations over the time intervals 1976-1996. During day-time measured data from Manila station are higher than those from Ouagadougou station. That may lie in that Manila is closer to equatorial ionization crest region. During solar minimum phase, the longitudinal variation of foF2 shows two crossing points (11:00 UT and 22:00 UT) between the foF2 profiles form the two stations for all seasons regardless of the solar cycle. However during intense solar activity condition, the number of crossing-point between measured data from Manila and Ouagadougou stations varies by seasons and solar cycle. This phenomenon may be due to the compilations of severe activities (storms, coronal mass ejection, heliosheet fluctuations) during the solar maximum phases.展开更多
In this paper, we construct a backward difference scheme for a class of SIR epidemic model with general incidence f . The step sizeτ used in our discretization is one. The dynamical properties are investigated (posit...In this paper, we construct a backward difference scheme for a class of SIR epidemic model with general incidence f . The step sizeτ used in our discretization is one. The dynamical properties are investigated (positivity and the boundedness of solution). By constructing the Lyapunov function, the general incidence function f must satisfy certain assumptions, under which, we establish the global stability of endemic equilibrium when R0 >1. The global stability of diseases-free equilibrium is also established when R0 ≤1. In addition we present numerical results of the continuous and discrete model of the different class according to the value of basic reproduction number R0.展开更多
Peanut shells from Burkina Faso were characterized using mineralogical, microstructural and chemical methods to perform its possibility to be used as reinforce in adobe bricks. It consists of cellulose (48 wt%), hemic...Peanut shells from Burkina Faso were characterized using mineralogical, microstructural and chemical methods to perform its possibility to be used as reinforce in adobe bricks. It consists of cellulose (48 wt%), hemicellulose (3 wt%) and lignin (28 wt%). The peanut shells were characterized by high porosity and showed water absorption around 198% at 72 hours. Its chemical composition is essentially composed of silica, iron oxides, alumina and calcium oxide. Its microstructure showed that the peanut shells were a compilation of microfibers with high porous of borders. In watery solution, the peanut shells released polyphenols. Thermal conductivity of peanut at 25 °C was <span>0.155 ± 0.021 W/mK. The physico-chemical characteristics of peanut shells were similar to those found with agricultural by-products used in adobe reinforce.</span>展开更多
<b><i><span>Background</span></i></b><span>: Achieving and maintaining glycemic targets </span><span>are</span><span> a challenge for health pract...<b><i><span>Background</span></i></b><span>: Achieving and maintaining glycemic targets </span><span>are</span><span> a challenge for health practitioners around the world. We aimed to study the factors associated with prolonged poor diabetes control in the cohort of T2DM patients monitored and treated in the Department of Internal Medicine at the Yalgado OUEDRAOGO Teaching Hospital in Ouagadougou in order to optimize therapeutic education in these patients. </span><b><i><span>Methodology</span></i></b><span>: This was a descriptive and analytical cross-sectional study combining retrospective data collection from the last year of patient follow-up and prospective collection of some information. The study included all diabetic patients, aged at least 18 years old, followed and treated in the Department of Internal Medicine at the Yalgado OUEDRAOGO Teaching Hospital between January 1, 2010 and December 31, 2018 following a systematic random sampling with a sampling step of 10. The variables collected were sociodemographic, anthropometric, lifestyle, cardiovascular risk factors and diabetes-related characteristics. To determine the risk factors associated with prolonged poor glycemic control, we performed modeling using logistic regression. All variables associated with prolonged poor glycemic control, in bivariate logistic regression with a p-value less than 0.20 were included in the full model. Later, we used a stepwise descending method to obtain the final model, which was then tested by a receiver operating characteristic (ROC) curve. The significance threshold was set at 5%. Raw and fitted Odds-Ratio (OR) and 95% confidence interval were presented. </span><b><i><span>Results</span></i></b><span>: 270 patients were included. Prolonged poor control of diabetes mellitus was observed in 73.70%. The mean age was 55.97 years (SD: ±11.52) and the sex ratio was 0.6 in favor of female. The mean time since diabetes mellitus diagnoses was 5.85 years (SD: ±5.15). A monthly gain of 92.62 USD (50.74%) for average diabetes mellitus care expenditures of 55.82 USD (SD: 28.25) was reported. An overweight (55.92%) and hypertension (41.85%) were reported. Diabetes mellitus was complicated in 68.15%. Patients were supported by their families in the management of their diabetes mellitus in 85.19%. In multivariate analysis with bivariate logistic regression, low level of formal education (OR = 8.34, 95% CI [1.97 - 35.22];</span><i><span>p</span></i><span> < 0.01), family support for diabetes mellitus management (OR = 0.65, 95% CI [0.45 - 0.94];</span><i><span>p</span></i><span> = 0.02), presence of abdominal obesity (OR = 2.27, 95% CI [1.08 - 4.77];</span><i><span>p</span></i><span> = 0.03), presence of a history of hospitalization (OR = 7.39, 95% CI [2.97 - 18.39];</span><i><span>p</span></i><span> < 0.01), poor adherence to antidiabetic treatment (OR = 2.97, 95% CI [1.42 - 6.18];</span><i><span>p</span></i><span> < 0.01), and the presence of microangiopathy (OR = 5.05, 95% CI [2.36 - 10.81];</span><i><span>p</span></i><span> < 0.01) were the factors independently associated with prolonged poor control of T2DM, with a ROC curve of 0.88, which reflects a very good sensitivity and specificity of these factors. </span><b><i><span>Conclusion</span></i></b><b><span>: </span></b><span>The imbalance of T2DM is multifactorial. Lifestyle, family environment, and compliance seem to be essential to ensure good glycemic control. Healthcare practitioners should take these elements into account in their daily patient assessment. A predictive score would be a tool to help identify patients at risk of diabetes imbalance and would contribute to improv</span><span>ing</span><span> their management.</span>展开更多
文摘In this study we review the occurrence of different types (A, B, C, M, and X classes) of solar flares during different solar cycle phases from 1996 to 2019 covering the solar cycles 23 and 24. During this period, a total of 19,126 solar flares were observed regardless the class: 3548 flares in solar cycle 23 (SC23) and 15,668 flares in solar cycle 24 (SC24). Our findings show that the cycle 23 has observed the highest occurrences of M-class and X-class flares, whereas cycle 24 has pointed out a predominance of B-class and C-class flares throughout its different phases. The results indicate that the cycle 23 was magnetically more intense than cycle 24, leading to more powerful solar flares and more frequent geomagnetic storms, capable of generating significant electromagnetic emissions that can affect satellites and GPS signals. The decrease in intense solar flares during cycle 24 compared to cycle 23 reflects an evolution in solar activity patterns over time.
文摘Staphylococcus aureus (S. aureus) is a bacterial pathogen for humans and animals. These bacteria can resist against many antibiotics and this resistance constitute an alarming worldwide human health threat due to the morbidity and mortality. Phage therapy is one of the alternative treatments. The aim of this study was to isolate and characterize lytic phages of S. aureus from different wastewater sources in Bobo-Dioulasso, Burkina Faso. Eight strains of S. aureus were isolated from different clinical samples and were used to isolate phages. The isolation and host range of phages were done by the spot test. Phages were purified by the double-layer method. Similar phages after the determination of the host range were characterized using restriction enzymes. A total of 27 phages were obtained after isolation and purification. Nine of the 27 isolates reported a broad host range (≥67%). The results of enzymatic digestion allowed to consider that all phage isolates that presented the same host range and the same genetic fingerprint are the same phage strain;whereas phages that presented the same host range and different genetic fingerprints are different phage strains. Thus, a total of 15 distinct phages isolates specific to S. aureus were characterized. This study highlighted the abundance and lytic capacity of phages isolated from wastewater from Bobo-Dioulasso’s environment against clinical strains of S. aureus. The lytic capacity of these Staphyphages could be an effective alternative tool to combat bacteria multi-resistance.
文摘In this study, we examined variability of sun-related energies, auroral electrojet current, ring current, and magnetopause current during solar cycles 23 and 24. The study revealed a dependence of sun-related energies to the Sun and Earth currents systems with solar activity from 1996 to 2019. A decrease in the correlation between sun-related energies and sunspot number was observed over solar cycles 23 and 24 (0.88 for the solar cycle 23 and 0.66 for the solar cycle 24), with a drop in the speed of magnetic disturbances in the solar wind. These results could be attributed to the decrease in Sun’s magnetic field toroidal component magnitude induced by a weak in sunspots number and solar flares during the solar cycle 24. A weak in the Earth currents systems (auroral electrojet current, ring current, and magnetopause current) is also observed. During the decrease in the Earth currents, several peaks are observed, indicating a nonlinear dependence in the Earth currents variation (ring current, auroral electrojet current, and magnetopause current) from solar cycle 23 to solar cycle 24. This could be attributed to the Corotating Interaction Regions (CIRs) observed during the declining phase of solar cycle 23 and the deep minimum preceding solar cycle 24.
文摘One of the most promising vector control strategies for controlling dengue fever is the stable introduction of the obligate intracellular Wolbachia bacteria strain into Aedes aegypti mosquitoes. This method reduces the mosquito’s ability to transmit dengue through reproductive strategies associated with Wolbachia infection, such as parthenogenesis, male elimination or feminization, sex ratio distortions and cytoplasmic incompatibility. Expert knowledge and a risk assessment framework were used to identify the risks associated with the release of Wolbachia-bearing mosquitoes. Then, consultations with individual participants were organized and a Bayesian network (BN) was developed to capture the relationship between the hazards as well as the likelihood of these adverse events occurring. Finally, risk was calculated from the probability and consequence estimates obtained from our Burkina Faso participants, using a questionnaire based on the identified risks. Our “Cause More Harm” study yielded 46.15% negligible risk, 44.23% very low risk and 9.62% low risk. The “socio-cultural change” parameter had the greatest influence, with the perception that the dissemination project would be poorly received by the local population. This parameter alone accounted for 80% of the most significant risks. This explains the fact that hazard RA 49 “negative messages in social media” is ranked as the highest individual risk (although the risk is low) with a calculated risk of 0.261. The risk assessment was designed to integrate the interdependent complexity of hazards likely to affect the dissemination of technology in the environment. It represents an important implementation phase in the success of this innovative research, introducing a new technology to combat the transmission of dengue fever.
文摘In Burkina Faso, as in other African countries, infertility has become a social burden for the population and a public health problem. Male infertility accounts for 30% to 40% of all infertility cases. The diagnosis of male infertility or hypofertility is often made by a simple laboratory analysis of sperm to explore sperm parameters. In most African countries, such as Burkina Faso, microbiological analysis in the context of sperm analysis is still not developed, and is carried out solely based on microscopy and traditional culture, which does not allow the growth of fragile and demanding bacteria. Our study investigated the microorganisms of sperm that may be involved in male infertility, using conventional bacteriology techniques and real-time PCR. However, it did not intend to perform a multivariate statistical association analysis to estimate the association of microorganisms with abnormal semen parameters. This prospective cross-sectional pilot study was carried out on patients who visited the bacteriology laboratory of Centre MURAZ, a research Institute in Burkina Faso, for male infertility diagnosis between 2 August and 31 August 2021. Bacteria were isolated and identified using standard bacteriology techniques. In parallel, common pathogenic microorganisms known to be associated with male infertility were targeted and detected in the sperm using a multiplex real-time PCR assay. A total of 38 sperm samples were analyzed by bacteriological culture and bacteria isolated were Staphylococcus aureus (S. aureus) 5.55%, Klebsiella pneumoniae (K. pneumoniae), Enterococcus faecalis (E. faecalis), Streptococcus agalactiae (S. agalactiae) and Staphylococcus hoemalyticus (S. hoemalyticus) respectively 2.70%. Real-time PCR targeted and detected Chlamydia trachomatis (C. trachomatis) at 7.89%, Ureaplasma urealyticum (U. urealyticum) at 21.05%, Ureaplasma parvum (U. parvum) at 18.42%, Mycoplasma hominis (M. hominis) at 15.79%, Mycoplasma genitalium (M. genitalium) at 10.53% and Trichomonas vaginalis (T. vaginalis) at 2.63%. Neisseria gonorrhoeae (N. gonorrhoeae) was targeted by the real-time PCR assay and was not detected (0%) in the tested semen samples. Our study highlights critical limitations of culture performance (low sensitivity), particularly in Burkina Faso, which has a total inability to detect microorganisms (fragile and demanding microorganisms) detected by PCR-based assays. There is therefore an urgent need to at least optimize culture, procedures and algorithms for detection of microorganisms associated with male infertility in clinical laboratories of Burkina Faso. The most effective solution is the routine implementation of molecular diagnostic methods.
文摘Antimicrobial resistance (AMR) is one of the top 10 threats to global health and it is estimated around 10 millions of deaths per year are associated with AMR until 2050. Burkina Faso is also facing the emergence and spread of AMR of several bacteria resistant strains such as those of public health concerns under surveillance Enterobacteriaceae. The aim of this study was to assess the prevalence of extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBL-PE) clinical isolates from patients attending the bacteriology laboratory of the Centre MURAZ in Bobo-Dioulasso, Burkina Faso. Clinical isolates from urine, pus, stool, and semen were collected from April to June 2017. Identification and antibiotic susceptibility testing were performed using the VITEK 2 compact automated system according to EUCAST version 2015 recommendations. ESBL detection was then performed on the Muller-Hinton medium using the combined disc method. One hundred (100) strains of Enterobacteriaceae were isolated from 100 patients, including 52% of ESBLS. Escherichia coli (E. coli) was the most commonly isolated ESBL [(84.62, 44/72) ESBL], followed by Klebsiella spp. [(40%, 06/15) ESBL], then Enterobacter spp. [(40%, 2/5) ESBL]. Risk factor analysis revealed that ESBL-PE infection was frequently found in pus samples (P = 0.042;[OR] = 3.16;95% [CI] = 1.04 - 9.61) and that E. coli was the strain most likely to harbour ESBL (P = 0.008;[OR] = 3.60;95% [CI] = 1.40 - 9.31). This study reports a high prevalence of ESBL-PE associated with strong resistance to quinolones and cotrimoxazole (over 80%), which calls for increased surveillance of these superbugs, the adoption of a rational antibiotic prescription policy, and rigorous hygiene measures to prevent the spread of these multi-resistant bacteria.
文摘This study examines the influence of magnetic field and temperature on the transient voltage of a polycrystalline silicon radial junction solar cell in a dynamic regime under multispectral illumination. Radial junction solar cells represent a major advancement in photovoltaic technologies, as they optimize light absorption and charge collection efficiency. The focus is on the impact of the magnetic field and temperature on the decay of transient voltage, which provides crucial information on recombination processes and the lifetime of minority carriers. The results reveal that the magnetic field tends to increase the transient voltage by directly affecting the transient electron density. Indeed, for B > 7 × 10−5 T, the magnetic field prolongs the relaxation time by increasing the transient voltage amplitude. Additionally, rising temperatures accelerate (ranging from 290 K to 450 K) recombination processes, thereby reducing the transient voltage, although this effect is moderated by the presence of a magnetic field. The study highlights the complex interaction between magnetic field and temperature, with significant impacts on the transient behaviour.
文摘In Burkina Faso, recent dengue outbreaks were exacerbated by Aedes aegypti mosquitoes, which have developed resistance to conventional insecticides. This study investigates the potential of Metarhizium pingshaense Met_S26, a fungus from Burkina Faso, for controlling both endophilic and exophilic Aedes mosquitoes. Traditional interventions are less effective against mosquitoes resting outdoors, and the ability of the fungus to be sexually transmitted could enhance its efficacy. Aedes mosquitoes were reared and exposed to various concentrations of Metarhizium pingshaense to assess its virulence. The fungus showed significant efficacy, with lethal times (LT80) ranging from 8.67 to 11.83 days depending on the concentration. Furthermore, bioassays demonstrated effective sexual auto-dissemination, with substantial transmission of fungal spores between infected and uninfected mosquitoes, leading to lower survival rates in uninfected mates. This study highlights Metarhizium pingshaense Met_S26 as a promising tool for controlling both indoor and outdoor Aedes populations, complementing existing vector control strategies such as the Sterile Insect Technique (SIT) and Wolbachia-based approaches. Future research should explore integrating this fungus with other control methods for a comprehensive vector management strategy.
文摘Over the last few decades, dengue fever epidemics have increased in frequency and intensity worldwide, making it a major global concern for public health. Its prevention, which is essentially vector-based control, is already being compromised by reports of resistance of the main vector Aedes aegypti to insecticides. To tackle the rapid increase in insecticide resistance and outbreaks, the biological vector control is a promising approach. One of the strategies of this approach is the use of entomopathogenic fungi because of their great efficacy and their eco-friendly aspects. However, some aspects of their use, such as the low efficiency, the high cost of production and the sensitivity to various adverse conditions, need to be addressed for their successful large-scale application. Therefore, innovative technologies based on strains of transgenic fungi with improved biocontrol potentials by genetic engineering are actively pursued. Although these modified mycoinsecticides are acclaimed for their better effectiveness against target insects, the main concern remains their potential adverse effects on the environment and human health. The present review is dedicated to giving an update on recent developments in transgenic entomopathogenic fungi (TEF) for Aedes mosquito control. Future perspectives are also proposed to address the safety concerns related to the release of transgenic entomopathogenic fungi into the environment.
文摘Migration is a complex demographic phenomenon.Its dynamics can be explained by several factors whose spatial and temporal evolution is not easy to control.That is why this article aims to understand the factors of migration from a spatiotemporal perspective to fill the gaps in the literature.The aim of this article is to analyse the spatiotemporal dynamics of internal migration factors to deduce the zones of origin and destination in Burkina Faso.To do this,several types of data were used.These included secondary,spatial,statistical and survey data.The results of this study show that the influence of internal migration factors is uneven.The spatial distribution of internal migration factors follows a north-south gradient,with favourable conditions in the south.In fact,the northern part is characterised by a large population exodus,with around 42.6%of outgoing internal migrants,and the southern part by a large population influx.This southern part of the country receives around 34.6%of internal migrants.The areas from which migrants depart have unfavourable climatic,environmental,or socio-economic conditions,whereas the areas to which migrants migrate are characterised by favourable conditions for these factors.
文摘Sexually transmitted infections (STIs) represent a public health problem due to their high prevalence worldwide and the emergence of multidrug resistance of responsible microorganisms. Medical laboratory diagnosis of sexually transmitted genital infections by traditional methods as culture remains extremely delicate, difficult or impossible (to find extremely fragile organisms that can be cultured). Thus, molecular techniques constitute an alternative to improve accurate diagnostic, personalized patient treatment, and public health. A total of 83 clinical samples including urethral discharge and urine samples from individual patients with symptoms of urethritis received were analyzed using traditional methods and a commercial real-time PCR (qPCR) method. Out of 83 urethritis patients, n = 55 (66.26%) were positive for at least one of the STI pathogens detected by qPCR. qPCR assay was more sensitive (50/83, positive cases) compared to culture (15/83, positive cases) and light microscopy (28/83, positive cases). The most prevalent NTD pathogen in the suspected patients was N. gonorrhoeae with 60.24% (50/83) based on real-time PCR diagnosis. Among the positive cases of STI pathogens, Neisseria gonorrhoeae had the highest frequency 49/55 (89.01%) followed by low frequencies of Trichomonas vaginalis 4/55 (7.27%) and Chlamydia trachomatis 1/55 (1.82%). This highlights the high prevalence of N. gonorrhoeae infection in male urethritis patients and a very important misdiagnosis using traditional routine methods in Burkina Faso by medical laboratories. Thus, this situation may negatively impact patients’ personalized treatment and care and public health with the possible rapid emergence of multidrug-resistant strains. This study also highlights the urgent need to optimize culture for the diagnosis of NTD pathogens in Burkina Faso and the usefulness and the need for the introduction of molecular diagnostic methods in routine diagnosis for the detection of NTD pathogens in the medical laboratories in Burkina Faso.
文摘This review explores the research activities surrounding the development and integration of smart electricity grids in Burkina Faso, a landlocked and arid territory in West Africa and one of the poorest countries in the world with significant energy challenges. It examines the current state of energy infrastructure in Burkina Faso, focusing on the integration of renewable energy sources, particularly solar photovoltaics. It highlights the role of smart grid technologies in enabling the efficient integration of renewable energy, improving grid stability and facilitating rural electrification. Additionally, the review addresses key challenges such as inadequate infrastructure, regulatory gaps and financial constraints that hinder the deployment of smart grids in the country. By analysing existing research and ongoing projects, this paper provides a comprehensive overview of the opportunities and barriers to implementing a smart electricity grid in Burkina Faso and offers recommendations for future development and policy frameworks.
文摘Malaria is a potentially lethal disease caused by parasites of the Plasmodium genus, transmitted to humans through the bite of infected female mosquitoes, primarily Anopheles. To control this disease, various strategies are implemented, including biological control, which targets the vectors of the parasite. This approach uses biological agents such as entomopathogenic fungi, including Metarhizium pingshaense, a fungus capable of causing lethal infections in mosquitoes. The production of Metarhizium pingshaense is still limited in Burkina Faso, and local cultivation of this fungus could help fill this gap. A study was conducted to identify optimal local substrates that promote its growth. Indeed, after gathering information on the dietary habits of populations in Bobo-Dioulasso and Bama, three potential substrates were selected: rice, cornmeal dough (MFL), and beans. These substrates were inoculated with two strains of Metarhizium pingshaense (S10 and S26) to assess their ability to support fungal growth and their effectiveness. Experimental results showed that MFL and bean substrates favored optimal growth of Metarhizium pingshaense, with growths of 1.91 cm and 2.13 cm after 8 days, compared to 1.83 cm on a standard media (PDA). In terms of virulence, S26 strain caused 60% mosquito mortality on both the bean and PDA media, while S10 strain induced mortalities of 50% for bean and 62% for PDA.
文摘Introduction: Arbovirus diseases such as dengue and chikungunya threaten public health worldwide. Early and rapid diagnosis and surveillance of dengue virus (DENV) and chikungunya virus (CHIKV) infections are essential to the control of these diseases. In this study, we evaluate the diagnostic performance of our new in-house multiplex RT-qPCR method for detecting DENV serotypes and CHIKV in an external laboratory. Methodology: The evaluation study was conducted on 200 clinical samples of suspected patients for arbovirus disease infection, collected in Centre de Recherche Biomoléculaire Pietro Annigoni (CERBA), Ouagadougou, Burkina Faso. Our new multiplex RT-qPCR was compared to the commercial kit, the Zika, Dengue, and Chikungunya (ZDC) Real-Time PCR Assays kit (Bio-Rad, California, USA). Results and Conclusions: Among 200 samples, 21.5% (43/200) were DENV-positive by multiplex RT-qPCR, and 21.5% (43/200) were also DENV-positive by reference real-time RT-PCR. 157 (78.5%) samples tested negative for DENV by both tests (new mRT-qPCR and reference test). The sensitivity and specificity of mRT-qPCR were 100%. The DENV serotypes detected were DENV-1 60.5% (26/43) and DENV-3 39.5% (17/43). CHIKV was not detected in this study. Our new mRT-qPCR is sensitive, cost-effective, simple, and can be used in developing country laboratories.
文摘Introduction: A recent study in Kenya highlighted a promising advance in malaria control by demonstrating that infecting mosquitoes with the endosymbiont Microsporidia MB blocks Plasmodium transmission. However, the influence of biotic and abiotic factors such as diet, relative humidity (RH) and temperature on this infection remains poorly studied. This study, aimed to gain a better understanding of this relationship. Methods: To highlight the influence of diet quantity, we defined a range of 3 quantities: 0.00375 g, 0.015 g and 0.09 g. Each quantity was tested on two groups of larvae: a group of 150 larvae infected with Microsporidia MB (MB+), and a group of 150 larvae not infected with Microsporidia MB (MB−) (control group), each divided into three replicates of 50 larvae. Each replicate was fed each morning with the assigned quantity until the pupal stage. In addition to this factor, we investigated the influence of temperature and RH. We defined three temperature-RH combinations: 21˚C-80% RH, 39˚C-50% RH, and 27˚C-75% RH. Each combination was tested on two groups of larvae: a group of 150 MB+ larvae and a group of 150 MB− larvae, each divided into three replicates of 50 larvae. Each replicate was subjected to the assigned combination until pupation. Pupae that had reached the adult stage were tested by PCR to determine their Microsporidia MB infection status for each factor studied. Results: The results showed that only the lowest quantity (0.00375 g) significantly reduced the prevalence of Microsporidia MB compared with the medium quantity (chi-2 test, χ2 = 4.9088, df = 1, p = 0.02672) and the high quantity (chi-2 test, χ2 = 4.7958, df = 1, p = 0.02853). As for temperature and RH, the combination 39˚C-50% RH led to a significant reduction in the prevalence of Microsporidia MB compared with the combination 27˚C-75% RH (chi-2 test, χ2 = 6.3736, ddl = 1, p = 0.01158) and that 21˚C-80% RH (chi-2 test, χ2 = 9.983, ddl = 1, p = 0.00158). Conclusion: This work contributes to a better understanding of some key factors linked to Microsporidia MB infection in mosquitoes. However, further research on several generations is necessary to draw more comprehensive conclusions.
文摘Background: According to the World Health Organization, the worldwide prevalence of infertility is 17.5%. The male share of responsibility is undeniable. Several factors, such as smoking, alcoholism, obesity and environmental pollution are sources of infertility in men. The aim of this study was to determine the spermological profile of infertile men and the factors associated with sperm parameter abnormalities. Methods: This retrospective study analysed 1000 sperm samples over an 11-year period, from January 2010 to December 2021. Results: The average age was 37.52 ± 8.66 years. Surgical history of varicocele and teratozoospermia were associated (p-value = 0.0001). Candida albicans was associated with a 2.27-fold risk of necrozoospermia and a 3.14-fold risk of oligozoospermia. The link between the reason for requesting a spermogram and the age range between 38 and 47 was significant (p-value Conclusion: Today, lifestyle and environmental pollution play a major role in sperm parameter abnormalities.
文摘In this paper we report on the foF2 variabilities for two equatorial regions (Ouagadougou: Lat. 12.4°N;Long. 358.5°E, Dip. 1.43°S;and Manila: Lat. 14°36'15.12''N;Long. 120°58'55.92''E;Dip. 0.6°S) during solar cycles 20 and 21 minima and maxima phases. Many previous works have argued on the diurnal and seasonal variation of foF2 for different solar events conditions for latitudinal position. But there are few investigations for Africa equatorial region longitudinal variation. The present paper’s goal is to outline possible similarity in foF2 behavior between variations for better understanding of physical process lead to some observed phenomenon in Asia-Africa equatorial sector. The F-layer critical frequency (foF2) data observed from the two equatorial ionosonde stations have been used for the present comparative study. The results show significant similarity between the critical frequency (foF2) seasonal variations over the time intervals 1976-1996. During day-time measured data from Manila station are higher than those from Ouagadougou station. That may lie in that Manila is closer to equatorial ionization crest region. During solar minimum phase, the longitudinal variation of foF2 shows two crossing points (11:00 UT and 22:00 UT) between the foF2 profiles form the two stations for all seasons regardless of the solar cycle. However during intense solar activity condition, the number of crossing-point between measured data from Manila and Ouagadougou stations varies by seasons and solar cycle. This phenomenon may be due to the compilations of severe activities (storms, coronal mass ejection, heliosheet fluctuations) during the solar maximum phases.
文摘In this paper, we construct a backward difference scheme for a class of SIR epidemic model with general incidence f . The step sizeτ used in our discretization is one. The dynamical properties are investigated (positivity and the boundedness of solution). By constructing the Lyapunov function, the general incidence function f must satisfy certain assumptions, under which, we establish the global stability of endemic equilibrium when R0 >1. The global stability of diseases-free equilibrium is also established when R0 ≤1. In addition we present numerical results of the continuous and discrete model of the different class according to the value of basic reproduction number R0.
文摘Peanut shells from Burkina Faso were characterized using mineralogical, microstructural and chemical methods to perform its possibility to be used as reinforce in adobe bricks. It consists of cellulose (48 wt%), hemicellulose (3 wt%) and lignin (28 wt%). The peanut shells were characterized by high porosity and showed water absorption around 198% at 72 hours. Its chemical composition is essentially composed of silica, iron oxides, alumina and calcium oxide. Its microstructure showed that the peanut shells were a compilation of microfibers with high porous of borders. In watery solution, the peanut shells released polyphenols. Thermal conductivity of peanut at 25 °C was <span>0.155 ± 0.021 W/mK. The physico-chemical characteristics of peanut shells were similar to those found with agricultural by-products used in adobe reinforce.</span>
文摘<b><i><span>Background</span></i></b><span>: Achieving and maintaining glycemic targets </span><span>are</span><span> a challenge for health practitioners around the world. We aimed to study the factors associated with prolonged poor diabetes control in the cohort of T2DM patients monitored and treated in the Department of Internal Medicine at the Yalgado OUEDRAOGO Teaching Hospital in Ouagadougou in order to optimize therapeutic education in these patients. </span><b><i><span>Methodology</span></i></b><span>: This was a descriptive and analytical cross-sectional study combining retrospective data collection from the last year of patient follow-up and prospective collection of some information. The study included all diabetic patients, aged at least 18 years old, followed and treated in the Department of Internal Medicine at the Yalgado OUEDRAOGO Teaching Hospital between January 1, 2010 and December 31, 2018 following a systematic random sampling with a sampling step of 10. The variables collected were sociodemographic, anthropometric, lifestyle, cardiovascular risk factors and diabetes-related characteristics. To determine the risk factors associated with prolonged poor glycemic control, we performed modeling using logistic regression. All variables associated with prolonged poor glycemic control, in bivariate logistic regression with a p-value less than 0.20 were included in the full model. Later, we used a stepwise descending method to obtain the final model, which was then tested by a receiver operating characteristic (ROC) curve. The significance threshold was set at 5%. Raw and fitted Odds-Ratio (OR) and 95% confidence interval were presented. </span><b><i><span>Results</span></i></b><span>: 270 patients were included. Prolonged poor control of diabetes mellitus was observed in 73.70%. The mean age was 55.97 years (SD: ±11.52) and the sex ratio was 0.6 in favor of female. The mean time since diabetes mellitus diagnoses was 5.85 years (SD: ±5.15). A monthly gain of 92.62 USD (50.74%) for average diabetes mellitus care expenditures of 55.82 USD (SD: 28.25) was reported. An overweight (55.92%) and hypertension (41.85%) were reported. Diabetes mellitus was complicated in 68.15%. Patients were supported by their families in the management of their diabetes mellitus in 85.19%. In multivariate analysis with bivariate logistic regression, low level of formal education (OR = 8.34, 95% CI [1.97 - 35.22];</span><i><span>p</span></i><span> < 0.01), family support for diabetes mellitus management (OR = 0.65, 95% CI [0.45 - 0.94];</span><i><span>p</span></i><span> = 0.02), presence of abdominal obesity (OR = 2.27, 95% CI [1.08 - 4.77];</span><i><span>p</span></i><span> = 0.03), presence of a history of hospitalization (OR = 7.39, 95% CI [2.97 - 18.39];</span><i><span>p</span></i><span> < 0.01), poor adherence to antidiabetic treatment (OR = 2.97, 95% CI [1.42 - 6.18];</span><i><span>p</span></i><span> < 0.01), and the presence of microangiopathy (OR = 5.05, 95% CI [2.36 - 10.81];</span><i><span>p</span></i><span> < 0.01) were the factors independently associated with prolonged poor control of T2DM, with a ROC curve of 0.88, which reflects a very good sensitivity and specificity of these factors. </span><b><i><span>Conclusion</span></i></b><b><span>: </span></b><span>The imbalance of T2DM is multifactorial. Lifestyle, family environment, and compliance seem to be essential to ensure good glycemic control. Healthcare practitioners should take these elements into account in their daily patient assessment. A predictive score would be a tool to help identify patients at risk of diabetes imbalance and would contribute to improv</span><span>ing</span><span> their management.</span>