Objective This study aimed to determine the temporal trends in sleep duration among Chinese adults.Methods In this series of repeated nationally representative cross-sectional surveys(China Chronic Disease and Risk Fa...Objective This study aimed to determine the temporal trends in sleep duration among Chinese adults.Methods In this series of repeated nationally representative cross-sectional surveys(China Chronic Disease and Risk Factors Surveillance)conducted between 2010 and 2018,a total of 645,420 adult participants(97,741 in 2010;175,749 in 2013;187,777 in 2015;and 184,153 in 2018)were included in the trend analysis.Linear and logistic regression models were utilized to assess trends in sleep duration.Results In 2018,the estimated overall mean sleep duration among the Chinese adult population was7.58(SD,1.45)hours per day,with no significant trend from 2010.A significant increase in short sleep duration(≤6 hours)was observed in the total population,from 15.3%(95%CI:14.1%–16.5%)in 2010 to18.5%(95%CI:17.7%–19.3%)in 2018(P<0.001).Similarly,the trend in long sleep duration(>9 hours)was also significant,increasing in weighted prevalence from 7.2%(95%CI:6.3%–8.1%)in 2010 to 9.0%(95%CI:8.2%–9.9%)in 2018(P<0.001).Conclusion The prevalence of both short and long sleep durations significantly increased among Chinese adults from 2010 to 2018,highlighting the urgency of health initiatives to promote optimal sleep duration in China.展开更多
AIM:To evaluate the clinical characteristics and risk factors associated with visual prognosis in patients with open globe injuries(OGIs)treated at Vietnam National Eye Hospital.METHODS:A prospective observational stu...AIM:To evaluate the clinical characteristics and risk factors associated with visual prognosis in patients with open globe injuries(OGIs)treated at Vietnam National Eye Hospital.METHODS:A prospective observational study included patients with OGIs treated between June 2023 and June 2024.Data on demographics,injury features,and clinical findings were extracted from medical records.Poor visual outcome was defined as final best-corrected visual acuity(BCVA)worse than 20/400 or no light perception.Multivariable logistic regression was performed to identify independent risk factors.RESULTS:Among 509 patients(636 eyes),the mean age was 35.13y(range 20–51y),and 67.6%were male.After treatment,the proportion of eyes achieving≥20/40 increased from 12.6%to 42.1%,while no light perception decreased from 29.1%to 9.4%.Independent predictors of poor visual outcomes included delayed admission[>4h,odds ratio(OR)=3.33,95%confidence intervals(CI):1.76–6.33,P<0.001],Zone III injury(OR=5.90,95%CI:2.85–12.24,P<0.001),wound length>10 mm(OR=2.59,95%CI:1.60–4.18,P<0.001),relative afferent pupillary defect(RAPD,OR=1.65,95%CI:1.03–2.64,P=0.039),endophthalmitis(OR=1.75,95%CI:1.01–3.03,P=0.047),retinal detachment(OR=3.32,95%CI:2.02–5.45,P<0.001),and eyelid lacerations(OR=1.94,95%CI:1.13–3.33,P=0.016)associated with OGIs.Vitreous hemorrhage(OR=0.44,95%CI:0.22–0.89,P=0.023)was associated with better outcomes,and female gender appeared protective.CONCLUSION:Poor visual outcomes remain common after OGIs,despite improve visual acuity in many cases.Several clinical and injury-related factors are strongly associated with prognosis.Early recognition of these predictors can support risk stratification and improve trauma care in similar settings.展开更多
Periodontitis has emerged as one of the most critical oral diseases, and research on this condition holds great importance for the advancement of stomatology. As the most authoritative national scientific research fun...Periodontitis has emerged as one of the most critical oral diseases, and research on this condition holds great importance for the advancement of stomatology. As the most authoritative national scientific research funding institution in China, the National Natural Science Foundation of China (NSFC) has played a pivotal role in driving the progress of periodontal science by supporting research on periodontitis. This article provides a comprehensive review of the research and development progress related to periodontitis in China from 2014 to 2023, highlighting the significant contributions of the NSFC to this field. We have summarized the detailed funding information from the NSFC, including the number of applicant codes, funded programs and the distribution of funded scholars. These data illustrate the efforts of the NSFC in cultivating young scientists and building research groups to address key challenges in national scientific research. This study offers an overview of the current hot topics, recent breakthroughs and future research prospects related to periodontitis in China.展开更多
This article explores the transformative role of digital education in overcoming geographic and systemic challenges in the Maldives,an archipelagic nation facing unique educational constraints.Leveraging digital tools...This article explores the transformative role of digital education in overcoming geographic and systemic challenges in the Maldives,an archipelagic nation facing unique educational constraints.Leveraging digital tools offers a critical solution to bridge these barriers and ensure accessible,quality education across the islands.The Maldives National University(MNU)has undertaken initiatives to expand digital education offerings,accelerated during the COVID-19 pandemic to facilitate online learning across the Maldives.Drawing on MNU’s 2021 study,“The Impact of COVID-19 Pandemic on the Higher Education Sector of Maldives:Responses and Challenges,”this paper examines challenges such as infrastructure limitations,digital literacy gaps,and student engagement,alongside MNU’s strategies to address these issues.This article also highlights MNU’s ongoing research initiatives,including participation in the EU Erasmus project DIGITAsia and a completed e-learning project with the EU,and discusses the value of international collaboration in advancing digital education.Furthermore,it outlines current government initiatives aimed at enhancing digital literacy among citizens.Future directions are discussed,including the integration of adaptive technologies to further personalize learning and prepare students for the demands of a global digital economy.展开更多
National awakening and the cultivation of national defense consciousness among the populace are deeply interconnected,forming a central narrative theme in Chinese films about the War of Resistance Against Japanese Agg...National awakening and the cultivation of national defense consciousness among the populace are deeply interconnected,forming a central narrative theme in Chinese films about the War of Resistance Against Japanese Aggression.The collective historical memory of the Chinese people’s wartime experience,which embodies the awakening of public defense consciousness,provides a significant historical reference for contemporary national defense development.This paper takes the film The Eight Hundred as a case study,analyzing its dialogues and scenes to trace the process through which national defense consciousness awakens among ordinary people.It concludes that such awakening is an inevitable outcome shaped by moral exemplars and cultural heritage.As an important medium of cultural transmission,War of Resistance-themed films not only construct and perpetuate national defense awareness through historical narratives but also inspire contemporary society to strengthen its defense consciousness through cinematic representation.Furthermore,these films serve as a window for international cross-cultural dialogue.Especially on the 80th anniversary of the victory in the War of Resistance,they showcase to the world the spiritual strength and national resilience of the Chinese people in resisting foreign aggression.展开更多
April 15,2025,was the 10th National Security Education Day of China.This year marks the 10th anniversary of the promulgation of the National Security Law of the People's Republic of China(PRC).Designating April 15...April 15,2025,was the 10th National Security Education Day of China.This year marks the 10th anniversary of the promulgation of the National Security Law of the People's Republic of China(PRC).Designating April 15 as National Security Education Day marked a milestone in the PRC's history of national security and education,aimed at shoring up weaknesses in China's national security education in line with the requirements presented by domestic and international situations.It is also an effective measure to apply a holistic approach to national security towards achieving high-level security.Over the past decade,China's national security education has made substantive progress in quality and efficiency,achieving remarkable results.It has significantly enhanced the public awareness of national security,the rule of law on the national security front,the knowledge and communication systems concerning national security,and China's capacity to safeguard and shape its security.The third plenary session of the 20th Central Committee of the Communist Party of China called for further deepening reform comprehensively to advance Chinese moder nization,putting for th higher requirements for national security education.On the way ahead,China should fully apply a holistic approach to national security by coordinating the following five aspects:the development of its national security education system and the strengthening of the rule of law;social education and school education;education content and education forms;intensive education and regular education;key areas and key groups.Doing so will provide a robust security guarantee for steadily advancing Chinese modernization.展开更多
Background:China accounts for one-quarter of the world’s diabetes population,with significant subnational disparities.However,none of the available data have provided comprehensive estimates and projections at both r...Background:China accounts for one-quarter of the world’s diabetes population,with significant subnational disparities.However,none of the available data have provided comprehensive estimates and projections at both regional and national levels in diabetes prevention and management.This study aimed to explore the temporal trends and geographical variations in the prevalence and non-fatal burden of diabetes by age and sex across China from 2005 to 2023,and to forecast diabetes prevalence through 2050.Methods:We conducted a population-based study based on the nationally representative surveys,and literature reviews.Using the DisMod-MR model and Chinese-specific disease disability weights,we estimated the non-fatal burdens of diabetes,including prevalence and years lived with disability(YLDs),across sexes,age groups,and locations.The temporal trend change was measured as the average annual percent change.The effect of the human development index on burdens was assessed by applying Spearman’s rank correlation analysis.We further projected diabetes prevalence to 2050 under 2 scenarios,the natural trend and the effective intervention on body mass index(BMI).Results:In 2023,an estimated 233 million individuals in China were living with diabetes.Compared to 2005,the agestandardized rate(ASR)of prevalence has increased by nearly 50%,from 7.53%(95%CI 7.00-8.10)to 13.7%(95%CI 12.6-14.8)in 2023.The ASR of YLDs was estimated at 19.1 per 1000 population(95%CI 18.6-19.5)in 2023,compared to 10.5 per 1000 population in 2005.The ASR of prevalence and YLDs was consistently higher in males than in females.The provinces with the highest diabetes prevalence and disease burden were Beijing,Tianjin,and Shanghai.Our forecast results suggest that if existing trends continue,the prevalence of obesity will reach 29.1%(95%CI 22.2-38.2)nationally by 2050,with some provinces in the northern region observing a prevalence of over 40%.Conversely,if effective obesity interventions were implemented,the growth in diabetes prevalence could potentially be suppressed by nearly 50%.Conclusions:The health burden and economic cost associated with diabetes are profound.There is an urgent need to scale up preventive efforts and improve population awareness to enhance disease management and achieve optimal treatment outcomes.展开更多
The Himalayan monal(Lophophorus impejanus),Nepal’s national bird,is a protected species facing significant conservation challenges.Understanding the distribution and habitat preferences of the Himalayan monal(HM)is c...The Himalayan monal(Lophophorus impejanus),Nepal’s national bird,is a protected species facing significant conservation challenges.Understanding the distribution and habitat preferences of the Himalayan monal(HM)is crucial for its conservation.This study was conducted in the Langtang National Park(LNP),Nepal using the route census method during both winter(November/December 2022)and summer(June 2023)seasons to examine the seasonal variation in HM’s elevational distribution and habitat preference.Further,we assessed their conservation threats by conducting a semi-structured questionnaire survey with the local residents.During the winter period,the HMs preferred grassland habitats,while in the summer,their preference shifted to shrubland and barren area.HM abundance was negatively associated with the Normalized Differential Vegetation Index(NDVI)and the shortest distance from the survey trails in the winter.The HMs actively avoided areas with high anthropogenic pressure.In the summer,they showed a wider elevational range up to 4400 m above sea level(a.s.l.),with a higher sighting frequency between 3600 and 3900 m a.s.l.The questionnaire survey of the local residents revealed that anthropogenic pressure such as poaching and free-ranging livestock grazing are the major threats to the species in the study area.This study provides valuable insight into the complex habitat preferences and critical threats faced by the HMs in LNP and underscores the urgent need for targeted conservation action.展开更多
Since last year,China’s inbound tourism market has accelerated its recovery.With the introduction and optimization of various facilitation policies and the development of new products,the inbound tourism market has s...Since last year,China’s inbound tourism market has accelerated its recovery.With the introduction and optimization of various facilitation policies and the development of new products,the inbound tourism market has shown unlimited potential for growth.According to data from the Data Center of the Ministry of Culture and Tourism,the number of inbound tourists reached a new high during the Spring Festival in 2025.The UK became China's third largest source of inbound tourists after the Republic of Korea and Japan.展开更多
AIM:To investigate whether blood urea nitrogen to serum albumin ratio(BAR)influences the onset and progression of diabetic retinopathy(DR)in diabetic patients.METHODS:The diabetic individuals were extracted from the N...AIM:To investigate whether blood urea nitrogen to serum albumin ratio(BAR)influences the onset and progression of diabetic retinopathy(DR)in diabetic patients.METHODS:The diabetic individuals were extracted from the National Health and Nutrition Examination Survey(NHANES)database spanning 1999 to 2018.The BAR was calculated as the ratio of blood urea nitrogen to serum albumin.To evaluate the association between BAR levels and DR,a generalized additive model and multivariate logistic regression analysis were performed.Additionally,subgroup analyses were conducted to determine whether other factors modified this association.RESULTS:The number of eligible individuals in the current research endeavor equaled 5798.The resulting data were indicative of the existence of a nearly linearly positive relationship between BAR levels and DR.Following confounding variable adjustment(age,gender,marital status,red blood cell,hemoglobin,lactate dehydrogenase,uric acid,creatinine,gender,red cell distribution width,highdensity lipoprotein,glucose,sodium,glycated hemoglobin,hypertension,and total cholesterol),the multivariate investigation implied that an elevated DR risk correlated with elevated levels of BAR(OR:1.46,95%CI:1.20-1.79).This relationship was noted to be reliable and stable across diverse analyses,following the conduction of sensitivity analysis(P for trend:0.0002).Subgroup analysis showed no statistically significant interactions between BAR and most other risk factors for DR.CONCLUSION:The study provides evidence of a positive association between elevated BAR levels and an increased risk of DR in diabetic individuals.展开更多
Background Ischemic heart disease(IHD) represents the most significant disease burden among all cardiovascular diseases(CVDs). The increasing prevalence of metabolic risks in the 21st century has a profound impact on ...Background Ischemic heart disease(IHD) represents the most significant disease burden among all cardiovascular diseases(CVDs). The increasing prevalence of metabolic risks in the 21st century has a profound impact on the disease burden associated with IHD. We analyzed the global, regional, and national burdens of IHD attributable to metabolic risks from 1990 to 2021.Methods The data were taken from Global Burden of Disease(GBD) study 2021. Deaths, disability-adjusted life years(DALYs),the average annual percent change(AAPC), age-standardized death rates per 100,000 persons(ASDR) and age-standardized rate per 100,000 persons(ASR) of DALYs ranging from 1990 to 2021, were extracted and stratified according to region, nationality, socio-demographic index(SDI), sex, and age. Additionally, the global future trends were predicted using Nordpred prediction model.Results Compared to 1990, in 2021, the number of death and DALYs from metabolic risk-attributed IHD increased globally by67.35% and 59.91%, respectively;whereas ASDR and ASR of DALYs showed a decreasing trend and the most severe impact was observed in male and elderly populations. In addition, the burden of disease showed an inverted V-shaped relationship with SDI from 1990 to 2021. AAPC showed a significant increase in developing countries and a decrease in developed countries. We also analyzed the effects of different risk factors including metabolic risk factors on IHD in different SDI regions and genders. The prediction of future disease burden showed that the number of death and DALYs will keep rising, while ASDR and ASR of DALYs will maintain a certain downward trend.Conclusions The results of this study highlighted the need for screening and intervention for metabolic risk factors in specific regions and populations, this should call for increased collaboration between developing and developed countries to reduce the burden of disease and improve the prognosis of patients with IHD.展开更多
Long-distance oil and gas pipelines are important infrastructure for ensuring the security of national energy supply.There is still a certain gap between safety management requirements and systematic construction of r...Long-distance oil and gas pipelines are important infrastructure for ensuring the security of national energy supply.There is still a certain gap between safety management requirements and systematic construction of relevant regulations and standards for long-distance pipelines in China and those of EU countries.By means of literature review and standard comparison,the differences in key indicators such as design coefficient,regional grade classification.展开更多
Research conducted in U Minh Thuong National Park to assess carbon storage from fires and water on forest growth and regeneration.In 2003 after forest fire,measures were implemented to promote forest regeneration,affo...Research conducted in U Minh Thuong National Park to assess carbon storage from fires and water on forest growth and regeneration.In 2003 after forest fire,measures were implemented to promote forest regeneration,afforestation,and rainwater storage,aim to prevent future forest fires.Investigating established in 2023 on the thicknesses of(20–40 cm),(40–60 cm),(60–80 cm)of the 500 m2 per plot,with 5 replications,measuring growth and analyzing peat chemistry.Contents include:Assessing changes in peat and carbon reserves Melaleuca forests before and after forest fires;analysis of peat and water chemical properties during seasonal floods,assessing Melaleuca growth,and the relationship between soil chemistry and growth due to higher water levels 20 years after forest fire.The results show a large volume of peat and carbon reserves,accumulated over thousands of years,destroyed by forest fires;lost in large quantities due to frequent flooding,leading to organic matter decomposition.Melaleuca grows slowly and death ratio increases after 20 years.Study also determined soil and water chemistry by seasonal flood;relationship between peat chemical indicators and Melaleuca growth on peat thickness.Results assessed the total peat volume and carbon stocks accumulated over thousands of years of Melaleuca Forest history,the effects of forest fires and water management on growth and chemical relationships,particularly after above-normal water levels were observed for 20 years.Results are research changes in peat.展开更多
With the rapid development of aviation industry and its increasing impact on the global climate change,the contributions of carbon emissions frominternational flights are attracting more and more attention worldwide.T...With the rapid development of aviation industry and its increasing impact on the global climate change,the contributions of carbon emissions frominternational flights are attracting more and more attention worldwide.This study,taking Macao as the aviation hub,established the cross-border aviation carbon emission evaluation model to explore dynamic carbon emissions and net-zero path of international flights.The aviation hubmainly covers 58 routes and five types of civil aircraft from 12 countries or regions during 2000-2022.The results show that the aviation transportation in Macao emitted about 1.44 million tons CO_(2)eq in 2019,which is high 3.6 times that of 2000.The COVID-19 has led to a rapid decline in aviation carbon emissions in a short period of time,carbon emissions in 2020 decreased by 80%compared to 2019.In terms of cumulative carbon emissions from 2000 to 2019,the A321 and A320 Airbus contribute to 80%of carbon emissions.And the Chinese mainland(37%)and Taiwan(29%)are the main sources of emissions.In 2000-2019,the proportion of carbon emissions from China(including Taiwan and Hong Kong)decrease from 91%to 53%,while the contribution from Southeast Asia(from 5% to 26%),Japan and South Korea(from 2% to 19%)keep the growth trends.In the optimal scenario(B3C3),net zero emissions of cross-border aviation in Macao can be not achieved,and there is still only by removing 0.3 million tons CO_(2)eq.Emission reduction technology and new energy usage are priorities for the aviation emission reduction.展开更多
General Secretary of the Communist Party of China(CPC)Central Committee Xi Jinping has creatively put forward a holistic approach to national security and the path of national security with Chinese characteristics,whi...General Secretary of the Communist Party of China(CPC)Central Committee Xi Jinping has creatively put forward a holistic approach to national security and the path of national security with Chinese characteristics,which are synergistic and inseparable.Compared with other major global powers,China is embarking on a path of national security that incorporates distinctive Chinese characteristics.Unlike the United States,which seeks international expansion and hegemony while pursuing national security,China is dedicated to maintaining global security and building a community with a shared future for humanity.Unlike Russia,which prioritizes national security over everything else,China places greater emphasis on balancing development and security.Unlike Europe and Japan,which entrust their national security to other countries,China has always adhered to the principle of independence and self-reliance.An essential feature of the path of national security with Chinese characteristics is that it upholds the unity of the people’s security,political security,and the supremacy of national interests.Moreover,China will remain committed to peaceful development while defending its interests.China will continue to balance development and security imperatives,maintaining an independent foreign policy while building a community with a shared future for humanity.To make solid strides on the path of national security with Chinese characteristics,the fundamental task will be pursuing a holistic approach to national security and implementing the Ten Upholds.展开更多
The reform stems from honesty and determination. Since 2005, organ donation and transplantation in China has undergone thorough reform, which complies with legislation requirements and ethical principles established b...The reform stems from honesty and determination. Since 2005, organ donation and transplantation in China has undergone thorough reform, which complies with legislation requirements and ethical principles established by the World Health Organization(WHO). Reform in China has demonstrated the unwavering confidence and utmost determination of the Chinese government and the Chinese transplantation community. The year 2015 marked a historic turning point when voluntary donations from Chinese citizens became the sole legitimate source for organ transplantation. Since 2015, China has gradually established and refined the “Chinese Mode” and “China System” for organ donation and transplantation, fulfilling its political pledge of reform, and has garnered international recognition, and fostered a social culture which promotes organ donation. This article reviewed the history of reform on organ donation and transplantation in China, presented a new pattern of establishment of organ donation system in the new era of the country, and the direction of advances in the future.展开更多
Objective:Cervical cancer is a growing concern in China,especially among women who reside in rural areas and older women.Understanding age-and region-specific trends in cervical cancer is vital for informing policy an...Objective:Cervical cancer is a growing concern in China,especially among women who reside in rural areas and older women.Understanding age-and region-specific trends in cervical cancer is vital for informing policy and assessing progress toward WHO elimination targets.Methods:The 2000±2020 data from 22 long-standing registries contributing to the China national cancer registry was analyzed to estimate age-standardized incidence and mortality rates(ASIR and ASMR,respectively).Joinpoint regression yielded an average annual percentage change(AAPC)stratified by age group(<35,35±64,65±74,and≥75 y)and by urban-rural area.The comparative analysis included GLOBOCAN Overtime data from selected Asia-Pacific countries.Results:The ASIR tripled in China between 2000 and 2020 before stabilizing(AAPC=6.5%),while the ASMR rose steadily(AAPC=3.9%).The urban incidence declined after 2009 among women<35 y,while rural trends were broadly stable.The ASIR and ASMR increased in urban areas among women 35±64 y of age,while rural areas had a rising ASIR and a stable ASMR,suggesting potential screening effects.In contrast,women≥65 y of age had a steadily increasing incidence and mortality in rural and urban areas.Australia and Republic of Korea had consistent declines in the ASIRs and ASMRs compared to other Asia-Pacific countries,whereas Japan exhibited rising trends.The Philippines experienced a surge in mortality rates,despite incidence rates remaining stable or declining.Conclusions:The cervical cancer burden in China has begun to plateau but large disparities persist by age and geography.To achieve elimination of cervical cancer,it is imperative to implement tailored strategies that prioritize the urgent expansion of HPV vaccination programs,the deployment of high-efficacy screening methods,and the universal access to treatment throughout the nation.展开更多
“Multidimensional international world”refers to understanding the world through multiple dimensions beyond traditional economic or political measures,fostering cross-cultural collaboration,and creating systems that ...“Multidimensional international world”refers to understanding the world through multiple dimensions beyond traditional economic or political measures,fostering cross-cultural collaboration,and creating systems that balance global integration with local needs.This also includes management of global business operations across diverse cultures in a multipolar international landscape.The paper briefs the developed and already tested in numerous applications high-level Spatial Grasp Model and Technology(SGT),which can help investigate and manage complex systems with a holistic spatial approach effectively covering various physical and virtual dimensions,their interrelations,and integration as a whole.Different areas will be investigated with examples of practical solutions in them and their combinations in a high-level Spatial Grasp Language(SGL),the key element of SGT.This allows for the creation and distributed management of very large spatial networks with different orientation which can be self-spreading,self-analyzing,self-modifying,and self-recovering in complex terrestrial and celestial environments,and also organize dynamic multi-networking solutions supporting global evolution and integrity.展开更多
This study aimed to quantify the carbon footprint of the National University of Juliaca(UNAJ)for the year 2023,in order to identify the main sources of greenhouse gas(GHG)emissions and provide a foundation for impleme...This study aimed to quantify the carbon footprint of the National University of Juliaca(UNAJ)for the year 2023,in order to identify the main sources of greenhouse gas(GHG)emissions and provide a foundation for implementing sustainable policies.The methodology was based on the greenhouse gas inventory approach outlined in ISO 14064-1,applying the operational control method to measure both direct and indirect emissions.Data on energy consumption,transportation,and purchased goods and services were collected using digital tools and surveys,and emissions were calculated in metric tons of CO_(2)equivalent(tCO_(2)e).The results indicate that UNAJ’s total carbon footprint in 2023 was 1,461.03 tCO_(2)e,with per capita emissions of 0.47 tCO_(2)e per person.The main sources of emissions were transportation,accounting for 75.88%of total emissions,followed by the consumption of goods and services(14.29%)and energy use(5.12%).Despite limitations in solid waste management,the study makes a valuable contribution to the development of sustainability strategies,emphasizing the urgent need for sustainable mobility policies,energy efficiency measures,and the adoption of responsible procurement practices.Furthermore,it highlights the importance of achieving carbon neutrality at UNAJ as a key objective in mitigating its environmental impact.The findings provide relevant insights from the Peruvian context and offer a basis for analyzing emissions at local universities,with practical implications for enhancing environmental management in higher education institutions.展开更多
Objective: Chronic osteomyelitis represents a frequent complication in young children, especially those with sickle cell disease. The aim of this study was to describe the epidemiological aspects and therapeutic impli...Objective: Chronic osteomyelitis represents a frequent complication in young children, especially those with sickle cell disease. The aim of this study was to describe the epidemiological aspects and therapeutic implications of chronic long-bone osteomyelitis in sickle-cell subjects aged 0 to 5 years at Zinder National Hospital. Methodology: This is a descriptive study with retrospective data collection of sickle cell subjects hospitalized and treated for chronic osteomyelitis from November 2023 to October 2024 at Zinder National Hospital. Results: Of the 16 patients included, male sex predominated in 56.25% (9/16). The mean age of patients was 32.69 months, ranging from 12 to 54 months. Involvement was multifocal in 75% (12/16) and bilateral in 37.5% (6/16). Bone involvement was predominantly in the pelvic limbs (87.5%). Among the bones affected, the femur was the most frequent site of involvement. All patients presented clinical symptoms such as pain, fever and swelling. Hyperleukocytosis was present in all subjects. Abscesses were present in 93.75% of cases, and sequestration was observed in 37.5% of patients. All cases were managed medico-surgically. Complications were noted in 25% (4/16), and involved residual bone deformities. Cure was confirmed in 43.75% (7/16). Conclusion: Chronic osteomyelitis in sickle-cell patients is a serious complication of acute osteomyelitis. Early management of acute osteomyelitis helps to avoid.展开更多
基金supported by the National Natural Science Foundation of China(82341245,82371491)the Chinese Central Government(Key Project of Public Health Program)the National Key Research and Development Program of China(2018YFC1311706,2018YFC1311702)。
文摘Objective This study aimed to determine the temporal trends in sleep duration among Chinese adults.Methods In this series of repeated nationally representative cross-sectional surveys(China Chronic Disease and Risk Factors Surveillance)conducted between 2010 and 2018,a total of 645,420 adult participants(97,741 in 2010;175,749 in 2013;187,777 in 2015;and 184,153 in 2018)were included in the trend analysis.Linear and logistic regression models were utilized to assess trends in sleep duration.Results In 2018,the estimated overall mean sleep duration among the Chinese adult population was7.58(SD,1.45)hours per day,with no significant trend from 2010.A significant increase in short sleep duration(≤6 hours)was observed in the total population,from 15.3%(95%CI:14.1%–16.5%)in 2010 to18.5%(95%CI:17.7%–19.3%)in 2018(P<0.001).Similarly,the trend in long sleep duration(>9 hours)was also significant,increasing in weighted prevalence from 7.2%(95%CI:6.3%–8.1%)in 2010 to 9.0%(95%CI:8.2%–9.9%)in 2018(P<0.001).Conclusion The prevalence of both short and long sleep durations significantly increased among Chinese adults from 2010 to 2018,highlighting the urgency of health initiatives to promote optimal sleep duration in China.
文摘AIM:To evaluate the clinical characteristics and risk factors associated with visual prognosis in patients with open globe injuries(OGIs)treated at Vietnam National Eye Hospital.METHODS:A prospective observational study included patients with OGIs treated between June 2023 and June 2024.Data on demographics,injury features,and clinical findings were extracted from medical records.Poor visual outcome was defined as final best-corrected visual acuity(BCVA)worse than 20/400 or no light perception.Multivariable logistic regression was performed to identify independent risk factors.RESULTS:Among 509 patients(636 eyes),the mean age was 35.13y(range 20–51y),and 67.6%were male.After treatment,the proportion of eyes achieving≥20/40 increased from 12.6%to 42.1%,while no light perception decreased from 29.1%to 9.4%.Independent predictors of poor visual outcomes included delayed admission[>4h,odds ratio(OR)=3.33,95%confidence intervals(CI):1.76–6.33,P<0.001],Zone III injury(OR=5.90,95%CI:2.85–12.24,P<0.001),wound length>10 mm(OR=2.59,95%CI:1.60–4.18,P<0.001),relative afferent pupillary defect(RAPD,OR=1.65,95%CI:1.03–2.64,P=0.039),endophthalmitis(OR=1.75,95%CI:1.01–3.03,P=0.047),retinal detachment(OR=3.32,95%CI:2.02–5.45,P<0.001),and eyelid lacerations(OR=1.94,95%CI:1.13–3.33,P=0.016)associated with OGIs.Vitreous hemorrhage(OR=0.44,95%CI:0.22–0.89,P=0.023)was associated with better outcomes,and female gender appeared protective.CONCLUSION:Poor visual outcomes remain common after OGIs,despite improve visual acuity in many cases.Several clinical and injury-related factors are strongly associated with prognosis.Early recognition of these predictors can support risk stratification and improve trauma care in similar settings.
文摘Periodontitis has emerged as one of the most critical oral diseases, and research on this condition holds great importance for the advancement of stomatology. As the most authoritative national scientific research funding institution in China, the National Natural Science Foundation of China (NSFC) has played a pivotal role in driving the progress of periodontal science by supporting research on periodontitis. This article provides a comprehensive review of the research and development progress related to periodontitis in China from 2014 to 2023, highlighting the significant contributions of the NSFC to this field. We have summarized the detailed funding information from the NSFC, including the number of applicant codes, funded programs and the distribution of funded scholars. These data illustrate the efforts of the NSFC in cultivating young scientists and building research groups to address key challenges in national scientific research. This study offers an overview of the current hot topics, recent breakthroughs and future research prospects related to periodontitis in China.
文摘This article explores the transformative role of digital education in overcoming geographic and systemic challenges in the Maldives,an archipelagic nation facing unique educational constraints.Leveraging digital tools offers a critical solution to bridge these barriers and ensure accessible,quality education across the islands.The Maldives National University(MNU)has undertaken initiatives to expand digital education offerings,accelerated during the COVID-19 pandemic to facilitate online learning across the Maldives.Drawing on MNU’s 2021 study,“The Impact of COVID-19 Pandemic on the Higher Education Sector of Maldives:Responses and Challenges,”this paper examines challenges such as infrastructure limitations,digital literacy gaps,and student engagement,alongside MNU’s strategies to address these issues.This article also highlights MNU’s ongoing research initiatives,including participation in the EU Erasmus project DIGITAsia and a completed e-learning project with the EU,and discusses the value of international collaboration in advancing digital education.Furthermore,it outlines current government initiatives aimed at enhancing digital literacy among citizens.Future directions are discussed,including the integration of adaptive technologies to further personalize learning and prepare students for the demands of a global digital economy.
文摘National awakening and the cultivation of national defense consciousness among the populace are deeply interconnected,forming a central narrative theme in Chinese films about the War of Resistance Against Japanese Aggression.The collective historical memory of the Chinese people’s wartime experience,which embodies the awakening of public defense consciousness,provides a significant historical reference for contemporary national defense development.This paper takes the film The Eight Hundred as a case study,analyzing its dialogues and scenes to trace the process through which national defense consciousness awakens among ordinary people.It concludes that such awakening is an inevitable outcome shaped by moral exemplars and cultural heritage.As an important medium of cultural transmission,War of Resistance-themed films not only construct and perpetuate national defense awareness through historical narratives but also inspire contemporary society to strengthen its defense consciousness through cinematic representation.Furthermore,these films serve as a window for international cross-cultural dialogue.Especially on the 80th anniversary of the victory in the War of Resistance,they showcase to the world the spiritual strength and national resilience of the Chinese people in resisting foreign aggression.
文摘April 15,2025,was the 10th National Security Education Day of China.This year marks the 10th anniversary of the promulgation of the National Security Law of the People's Republic of China(PRC).Designating April 15 as National Security Education Day marked a milestone in the PRC's history of national security and education,aimed at shoring up weaknesses in China's national security education in line with the requirements presented by domestic and international situations.It is also an effective measure to apply a holistic approach to national security towards achieving high-level security.Over the past decade,China's national security education has made substantive progress in quality and efficiency,achieving remarkable results.It has significantly enhanced the public awareness of national security,the rule of law on the national security front,the knowledge and communication systems concerning national security,and China's capacity to safeguard and shape its security.The third plenary session of the 20th Central Committee of the Communist Party of China called for further deepening reform comprehensively to advance Chinese moder nization,putting for th higher requirements for national security education.On the way ahead,China should fully apply a holistic approach to national security by coordinating the following five aspects:the development of its national security education system and the strengthening of the rule of law;social education and school education;education content and education forms;intensive education and regular education;key areas and key groups.Doing so will provide a robust security guarantee for steadily advancing Chinese modernization.
基金supported by the National Key Research and Development Program of China(2023YFC3605000).
文摘Background:China accounts for one-quarter of the world’s diabetes population,with significant subnational disparities.However,none of the available data have provided comprehensive estimates and projections at both regional and national levels in diabetes prevention and management.This study aimed to explore the temporal trends and geographical variations in the prevalence and non-fatal burden of diabetes by age and sex across China from 2005 to 2023,and to forecast diabetes prevalence through 2050.Methods:We conducted a population-based study based on the nationally representative surveys,and literature reviews.Using the DisMod-MR model and Chinese-specific disease disability weights,we estimated the non-fatal burdens of diabetes,including prevalence and years lived with disability(YLDs),across sexes,age groups,and locations.The temporal trend change was measured as the average annual percent change.The effect of the human development index on burdens was assessed by applying Spearman’s rank correlation analysis.We further projected diabetes prevalence to 2050 under 2 scenarios,the natural trend and the effective intervention on body mass index(BMI).Results:In 2023,an estimated 233 million individuals in China were living with diabetes.Compared to 2005,the agestandardized rate(ASR)of prevalence has increased by nearly 50%,from 7.53%(95%CI 7.00-8.10)to 13.7%(95%CI 12.6-14.8)in 2023.The ASR of YLDs was estimated at 19.1 per 1000 population(95%CI 18.6-19.5)in 2023,compared to 10.5 per 1000 population in 2005.The ASR of prevalence and YLDs was consistently higher in males than in females.The provinces with the highest diabetes prevalence and disease burden were Beijing,Tianjin,and Shanghai.Our forecast results suggest that if existing trends continue,the prevalence of obesity will reach 29.1%(95%CI 22.2-38.2)nationally by 2050,with some provinces in the northern region observing a prevalence of over 40%.Conversely,if effective obesity interventions were implemented,the growth in diabetes prevalence could potentially be suppressed by nearly 50%.Conclusions:The health burden and economic cost associated with diabetes are profound.There is an urgent need to scale up preventive efforts and improve population awareness to enhance disease management and achieve optimal treatment outcomes.
基金an MSc thesis research grant from the Zoological Society of London(ZSL)Nepal.RCK’s effort was supported in part by the Office of Research Infrastructure Programs(ORIP)of the National Institutes of Health through grant number P51OD010425 to the Washington National Primate Research Center,USA。
文摘The Himalayan monal(Lophophorus impejanus),Nepal’s national bird,is a protected species facing significant conservation challenges.Understanding the distribution and habitat preferences of the Himalayan monal(HM)is crucial for its conservation.This study was conducted in the Langtang National Park(LNP),Nepal using the route census method during both winter(November/December 2022)and summer(June 2023)seasons to examine the seasonal variation in HM’s elevational distribution and habitat preference.Further,we assessed their conservation threats by conducting a semi-structured questionnaire survey with the local residents.During the winter period,the HMs preferred grassland habitats,while in the summer,their preference shifted to shrubland and barren area.HM abundance was negatively associated with the Normalized Differential Vegetation Index(NDVI)and the shortest distance from the survey trails in the winter.The HMs actively avoided areas with high anthropogenic pressure.In the summer,they showed a wider elevational range up to 4400 m above sea level(a.s.l.),with a higher sighting frequency between 3600 and 3900 m a.s.l.The questionnaire survey of the local residents revealed that anthropogenic pressure such as poaching and free-ranging livestock grazing are the major threats to the species in the study area.This study provides valuable insight into the complex habitat preferences and critical threats faced by the HMs in LNP and underscores the urgent need for targeted conservation action.
文摘Since last year,China’s inbound tourism market has accelerated its recovery.With the introduction and optimization of various facilitation policies and the development of new products,the inbound tourism market has shown unlimited potential for growth.According to data from the Data Center of the Ministry of Culture and Tourism,the number of inbound tourists reached a new high during the Spring Festival in 2025.The UK became China's third largest source of inbound tourists after the Republic of Korea and Japan.
基金Supported by the Wenzhou Municipal Basic Scientific Research Project(No.Y20220789).
文摘AIM:To investigate whether blood urea nitrogen to serum albumin ratio(BAR)influences the onset and progression of diabetic retinopathy(DR)in diabetic patients.METHODS:The diabetic individuals were extracted from the National Health and Nutrition Examination Survey(NHANES)database spanning 1999 to 2018.The BAR was calculated as the ratio of blood urea nitrogen to serum albumin.To evaluate the association between BAR levels and DR,a generalized additive model and multivariate logistic regression analysis were performed.Additionally,subgroup analyses were conducted to determine whether other factors modified this association.RESULTS:The number of eligible individuals in the current research endeavor equaled 5798.The resulting data were indicative of the existence of a nearly linearly positive relationship between BAR levels and DR.Following confounding variable adjustment(age,gender,marital status,red blood cell,hemoglobin,lactate dehydrogenase,uric acid,creatinine,gender,red cell distribution width,highdensity lipoprotein,glucose,sodium,glycated hemoglobin,hypertension,and total cholesterol),the multivariate investigation implied that an elevated DR risk correlated with elevated levels of BAR(OR:1.46,95%CI:1.20-1.79).This relationship was noted to be reliable and stable across diverse analyses,following the conduction of sensitivity analysis(P for trend:0.0002).Subgroup analysis showed no statistically significant interactions between BAR and most other risk factors for DR.CONCLUSION:The study provides evidence of a positive association between elevated BAR levels and an increased risk of DR in diabetic individuals.
基金supported by the National Natural Science Foundation of China (82070055 and 82470054)the Project Program of National Clinical Research Center for Geriatric Disorders (Xiangya Hospital, Grant No.2023LNJJ18)。
文摘Background Ischemic heart disease(IHD) represents the most significant disease burden among all cardiovascular diseases(CVDs). The increasing prevalence of metabolic risks in the 21st century has a profound impact on the disease burden associated with IHD. We analyzed the global, regional, and national burdens of IHD attributable to metabolic risks from 1990 to 2021.Methods The data were taken from Global Burden of Disease(GBD) study 2021. Deaths, disability-adjusted life years(DALYs),the average annual percent change(AAPC), age-standardized death rates per 100,000 persons(ASDR) and age-standardized rate per 100,000 persons(ASR) of DALYs ranging from 1990 to 2021, were extracted and stratified according to region, nationality, socio-demographic index(SDI), sex, and age. Additionally, the global future trends were predicted using Nordpred prediction model.Results Compared to 1990, in 2021, the number of death and DALYs from metabolic risk-attributed IHD increased globally by67.35% and 59.91%, respectively;whereas ASDR and ASR of DALYs showed a decreasing trend and the most severe impact was observed in male and elderly populations. In addition, the burden of disease showed an inverted V-shaped relationship with SDI from 1990 to 2021. AAPC showed a significant increase in developing countries and a decrease in developed countries. We also analyzed the effects of different risk factors including metabolic risk factors on IHD in different SDI regions and genders. The prediction of future disease burden showed that the number of death and DALYs will keep rising, while ASDR and ASR of DALYs will maintain a certain downward trend.Conclusions The results of this study highlighted the need for screening and intervention for metabolic risk factors in specific regions and populations, this should call for increased collaboration between developing and developed countries to reduce the burden of disease and improve the prognosis of patients with IHD.
基金Soft Science Research Project of the Special Equipment Safety and Energy Conservation Technology Committee of the State Administration for Market Regulation“Comparative Study of Special Equipment Supervision and Inspection Modes at Home and Abroad(AJW-2024-06)”Scientific Research and Technology Development Project of National Oil and Gas Pipeline Network Group Co.,Ltd.“Benchmarking of Pressure Pipeline(Long-Distance Pipeline)Regulatory System and Research on In-Service Pipeline Safety Management Technology(J-24-D08)”。
文摘Long-distance oil and gas pipelines are important infrastructure for ensuring the security of national energy supply.There is still a certain gap between safety management requirements and systematic construction of relevant regulations and standards for long-distance pipelines in China and those of EU countries.By means of literature review and standard comparison,the differences in key indicators such as design coefficient,regional grade classification.
基金Department of Science,Technology and Environment,Ministry of Education and Training Vietnam has supported project KGU1-B2024(2024–2025)the Faculty of Natural resources and Environment of Kien Giang University+1 种基金the U Minh Thuong National Park of Vietnamthe Southern Forestry Institute of Vietnam.
文摘Research conducted in U Minh Thuong National Park to assess carbon storage from fires and water on forest growth and regeneration.In 2003 after forest fire,measures were implemented to promote forest regeneration,afforestation,and rainwater storage,aim to prevent future forest fires.Investigating established in 2023 on the thicknesses of(20–40 cm),(40–60 cm),(60–80 cm)of the 500 m2 per plot,with 5 replications,measuring growth and analyzing peat chemistry.Contents include:Assessing changes in peat and carbon reserves Melaleuca forests before and after forest fires;analysis of peat and water chemical properties during seasonal floods,assessing Melaleuca growth,and the relationship between soil chemistry and growth due to higher water levels 20 years after forest fire.The results show a large volume of peat and carbon reserves,accumulated over thousands of years,destroyed by forest fires;lost in large quantities due to frequent flooding,leading to organic matter decomposition.Melaleuca grows slowly and death ratio increases after 20 years.Study also determined soil and water chemistry by seasonal flood;relationship between peat chemical indicators and Melaleuca growth on peat thickness.Results assessed the total peat volume and carbon stocks accumulated over thousands of years of Melaleuca Forest history,the effects of forest fires and water management on growth and chemical relationships,particularly after above-normal water levels were observed for 20 years.Results are research changes in peat.
基金supported by the Science and Technology Development Fund,Macao SAR,China(Nos.0033/2022/AFJ and 0011/2023/AMJ)Guangdong Basic and Applied Basic Research Foundation(No.2023A1515012017).
文摘With the rapid development of aviation industry and its increasing impact on the global climate change,the contributions of carbon emissions frominternational flights are attracting more and more attention worldwide.This study,taking Macao as the aviation hub,established the cross-border aviation carbon emission evaluation model to explore dynamic carbon emissions and net-zero path of international flights.The aviation hubmainly covers 58 routes and five types of civil aircraft from 12 countries or regions during 2000-2022.The results show that the aviation transportation in Macao emitted about 1.44 million tons CO_(2)eq in 2019,which is high 3.6 times that of 2000.The COVID-19 has led to a rapid decline in aviation carbon emissions in a short period of time,carbon emissions in 2020 decreased by 80%compared to 2019.In terms of cumulative carbon emissions from 2000 to 2019,the A321 and A320 Airbus contribute to 80%of carbon emissions.And the Chinese mainland(37%)and Taiwan(29%)are the main sources of emissions.In 2000-2019,the proportion of carbon emissions from China(including Taiwan and Hong Kong)decrease from 91%to 53%,while the contribution from Southeast Asia(from 5% to 26%),Japan and South Korea(from 2% to 19%)keep the growth trends.In the optimal scenario(B3C3),net zero emissions of cross-border aviation in Macao can be not achieved,and there is still only by removing 0.3 million tons CO_(2)eq.Emission reduction technology and new energy usage are priorities for the aviation emission reduction.
文摘General Secretary of the Communist Party of China(CPC)Central Committee Xi Jinping has creatively put forward a holistic approach to national security and the path of national security with Chinese characteristics,which are synergistic and inseparable.Compared with other major global powers,China is embarking on a path of national security that incorporates distinctive Chinese characteristics.Unlike the United States,which seeks international expansion and hegemony while pursuing national security,China is dedicated to maintaining global security and building a community with a shared future for humanity.Unlike Russia,which prioritizes national security over everything else,China places greater emphasis on balancing development and security.Unlike Europe and Japan,which entrust their national security to other countries,China has always adhered to the principle of independence and self-reliance.An essential feature of the path of national security with Chinese characteristics is that it upholds the unity of the people’s security,political security,and the supremacy of national interests.Moreover,China will remain committed to peaceful development while defending its interests.China will continue to balance development and security imperatives,maintaining an independent foreign policy while building a community with a shared future for humanity.To make solid strides on the path of national security with Chinese characteristics,the fundamental task will be pursuing a holistic approach to national security and implementing the Ten Upholds.
文摘The reform stems from honesty and determination. Since 2005, organ donation and transplantation in China has undergone thorough reform, which complies with legislation requirements and ethical principles established by the World Health Organization(WHO). Reform in China has demonstrated the unwavering confidence and utmost determination of the Chinese government and the Chinese transplantation community. The year 2015 marked a historic turning point when voluntary donations from Chinese citizens became the sole legitimate source for organ transplantation. Since 2015, China has gradually established and refined the “Chinese Mode” and “China System” for organ donation and transplantation, fulfilling its political pledge of reform, and has garnered international recognition, and fostered a social culture which promotes organ donation. This article reviewed the history of reform on organ donation and transplantation in China, presented a new pattern of establishment of organ donation system in the new era of the country, and the direction of advances in the future.
基金supported by a grant from the National Key Research and Development Program of China(No.2022YFC2409901)the Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences(2021-I2M-1-011)。
文摘Objective:Cervical cancer is a growing concern in China,especially among women who reside in rural areas and older women.Understanding age-and region-specific trends in cervical cancer is vital for informing policy and assessing progress toward WHO elimination targets.Methods:The 2000±2020 data from 22 long-standing registries contributing to the China national cancer registry was analyzed to estimate age-standardized incidence and mortality rates(ASIR and ASMR,respectively).Joinpoint regression yielded an average annual percentage change(AAPC)stratified by age group(<35,35±64,65±74,and≥75 y)and by urban-rural area.The comparative analysis included GLOBOCAN Overtime data from selected Asia-Pacific countries.Results:The ASIR tripled in China between 2000 and 2020 before stabilizing(AAPC=6.5%),while the ASMR rose steadily(AAPC=3.9%).The urban incidence declined after 2009 among women<35 y,while rural trends were broadly stable.The ASIR and ASMR increased in urban areas among women 35±64 y of age,while rural areas had a rising ASIR and a stable ASMR,suggesting potential screening effects.In contrast,women≥65 y of age had a steadily increasing incidence and mortality in rural and urban areas.Australia and Republic of Korea had consistent declines in the ASIRs and ASMRs compared to other Asia-Pacific countries,whereas Japan exhibited rising trends.The Philippines experienced a surge in mortality rates,despite incidence rates remaining stable or declining.Conclusions:The cervical cancer burden in China has begun to plateau but large disparities persist by age and geography.To achieve elimination of cervical cancer,it is imperative to implement tailored strategies that prioritize the urgent expansion of HPV vaccination programs,the deployment of high-efficacy screening methods,and the universal access to treatment throughout the nation.
文摘“Multidimensional international world”refers to understanding the world through multiple dimensions beyond traditional economic or political measures,fostering cross-cultural collaboration,and creating systems that balance global integration with local needs.This also includes management of global business operations across diverse cultures in a multipolar international landscape.The paper briefs the developed and already tested in numerous applications high-level Spatial Grasp Model and Technology(SGT),which can help investigate and manage complex systems with a holistic spatial approach effectively covering various physical and virtual dimensions,their interrelations,and integration as a whole.Different areas will be investigated with examples of practical solutions in them and their combinations in a high-level Spatial Grasp Language(SGL),the key element of SGT.This allows for the creation and distributed management of very large spatial networks with different orientation which can be self-spreading,self-analyzing,self-modifying,and self-recovering in complex terrestrial and celestial environments,and also organize dynamic multi-networking solutions supporting global evolution and integrity.
文摘This study aimed to quantify the carbon footprint of the National University of Juliaca(UNAJ)for the year 2023,in order to identify the main sources of greenhouse gas(GHG)emissions and provide a foundation for implementing sustainable policies.The methodology was based on the greenhouse gas inventory approach outlined in ISO 14064-1,applying the operational control method to measure both direct and indirect emissions.Data on energy consumption,transportation,and purchased goods and services were collected using digital tools and surveys,and emissions were calculated in metric tons of CO_(2)equivalent(tCO_(2)e).The results indicate that UNAJ’s total carbon footprint in 2023 was 1,461.03 tCO_(2)e,with per capita emissions of 0.47 tCO_(2)e per person.The main sources of emissions were transportation,accounting for 75.88%of total emissions,followed by the consumption of goods and services(14.29%)and energy use(5.12%).Despite limitations in solid waste management,the study makes a valuable contribution to the development of sustainability strategies,emphasizing the urgent need for sustainable mobility policies,energy efficiency measures,and the adoption of responsible procurement practices.Furthermore,it highlights the importance of achieving carbon neutrality at UNAJ as a key objective in mitigating its environmental impact.The findings provide relevant insights from the Peruvian context and offer a basis for analyzing emissions at local universities,with practical implications for enhancing environmental management in higher education institutions.
文摘Objective: Chronic osteomyelitis represents a frequent complication in young children, especially those with sickle cell disease. The aim of this study was to describe the epidemiological aspects and therapeutic implications of chronic long-bone osteomyelitis in sickle-cell subjects aged 0 to 5 years at Zinder National Hospital. Methodology: This is a descriptive study with retrospective data collection of sickle cell subjects hospitalized and treated for chronic osteomyelitis from November 2023 to October 2024 at Zinder National Hospital. Results: Of the 16 patients included, male sex predominated in 56.25% (9/16). The mean age of patients was 32.69 months, ranging from 12 to 54 months. Involvement was multifocal in 75% (12/16) and bilateral in 37.5% (6/16). Bone involvement was predominantly in the pelvic limbs (87.5%). Among the bones affected, the femur was the most frequent site of involvement. All patients presented clinical symptoms such as pain, fever and swelling. Hyperleukocytosis was present in all subjects. Abscesses were present in 93.75% of cases, and sequestration was observed in 37.5% of patients. All cases were managed medico-surgically. Complications were noted in 25% (4/16), and involved residual bone deformities. Cure was confirmed in 43.75% (7/16). Conclusion: Chronic osteomyelitis in sickle-cell patients is a serious complication of acute osteomyelitis. Early management of acute osteomyelitis helps to avoid.
