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Necessary prerequisites for evidence-based practice:results of investigating nurses'informatics competency and information literacy skills
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作者 Jamileh Farokhzadian Somayeh Jouparinejad +3 位作者 Mahdieh Montazeri Elham Bakhshipour Amirreza Sabzi Fatemeh Falahati-Marvast 《Frontiers of Nursing》 2024年第1期67-76,共10页
This study aimed to evaluate the correlation between nursing informatics(NI)competency and information literacy skills for evidencebased practice(EBP)among intensive care nurses.This cross-sectional study was conducte... This study aimed to evaluate the correlation between nursing informatics(NI)competency and information literacy skills for evidencebased practice(EBP)among intensive care nurses.This cross-sectional study was conducted on 184 nurses working in intensive care units(ICUs).The study data were collected through demographic information,Nursing Informatics Competency Assessment Tool(NICAT),and information literacy skills for EBP questionnaires.The intensive care nurses received competent and low-moderate levels for the total scores of NI competency and information literacy skills,respectively.They received a moderate score for the use of different information resources but a low score for information searching skills,different search features,and knowledge about search operators,and only 31.5%of the nurses selected the most appropriate statement.NI competency and related subscales had a significant direct bidirectional correlation with information literacy skills for EBP and its subscales(P<0.05).Nurses require a high level of NI competency and information literacy for EBP to obtain up-to-date information and provide better care and decision-making.Health planners and policymakers should develop interventions to enhance NI competency and information literacy skills among nurses and motivate them to use EBP in clinical settings. 展开更多
关键词 evidence-based practice nursing informatics nursing informatics competency information literacy critical care nursing
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Automatically Eye Detection with Different Gray Intensity Image Conditions 被引量:2
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作者 Mitra Montazeri Hossein Nezamabadi-pour Mahdieh Montazeri 《Computer Technology and Application》 2012年第8期525-532,共8页
One of the methods for biometric identification is facial features detection, and eye is an important facial feature in the face. In the recent years, automatically detecting eye with different image conditions is att... One of the methods for biometric identification is facial features detection, and eye is an important facial feature in the face. In the recent years, automatically detecting eye with different image conditions is attended. This paper proposes a method which can automatically detect eye in extensive range of images with different conditions. In the proposed method, first an image is enhanced by morphological operations then region of face is detected by hybrid projection function. To identify window of eye, vertical edge dominance map is used. The authors' method uses elliptical mask on eye image to detect center of pupil. The mask scans eye image to find minimum gray level because pupil is darkest part in eye image compared with 3 well-known methods. The accuracy of 99.53% on this This method has implemented on JAFFE face database and database confirms efficiency of the proposed method. 展开更多
关键词 Eye detection hybrid projection function vertical edge dominance map pupil detection.
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Reversal of multidrug resistance and antitumor promoting activity of 3-oxo-6β-hydroxy-β-amyrin isolated from Pistacia integerrima
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作者 ABDUR RAUF SAUD BAWAZEER +14 位作者 MUSLIM RAZA EMAN EL-SHARKAWY MD.HABIBUR RAHMAN MOHAMED A.EL-ESAWI GHIAS UDDIN BINA SSIDDIQUI ANEES AHMED KHALIL JOSEPH MOLNAR AKOS CSONKA DIÁNA SZABÓ HAROON KHAN MOHAMMAD SMUBARAK TAIBI BEN HADDA MUDYAWATI KAMARUDDIN SEEMA PATEL 《BIOCELL》 SCIE 2021年第1期139-147,共9页
The bioactive triterpenoid 3-oxo-6-β-hydroxy-β-amyrin(1)has been isolated from multiple plant sources.In this study,chloroform fraction of Pistacia integerrima extract was processed for the isolation of the compound... The bioactive triterpenoid 3-oxo-6-β-hydroxy-β-amyrin(1)has been isolated from multiple plant sources.In this study,chloroform fraction of Pistacia integerrima extract was processed for the isolation of the compound.The compound identity was confirmed by advanced spectroscopy technique.X-ray crystallography was applied for molecular structure confirmation.In addition,compound 1 was screen for its activity on reversal of MDR(multidrug resistance)mediated by P-gp(P-glycoprotein).This was accomplished by using rhodamine123 exclusion on multidrug-resistant human ABCB1 gene transfected mouse T-lymphoma cell line.Outcomes revealed that MDR reversing effect was comparable to verapamil as positive control in vitro.Treatment of TPA-induced tumor promotion with 3-oxo-6β-hydroxy-β-amyrin led to reduction in the applied anti-tumor promotion experiment.The chemo-preventive effect of 3-oxo-6β-hydroxy-β-amyrin was comparable to curcumin as positive control based on the reduction of immediate early tumor antigen expression.Molecular docking by applying Autodock Vina 1 and i-GEMDOCK v 2.1 tools indicated that compound 1 gives good docking results,as determined by their fitness score and specificity.Moreover,results showed that compound 1 isolated from Pistacia integerrima precisely attached to a region where co-crystallized ligand for receptor previously existed.Our findings may explain the use of Pistacia integerrima plant extracts as an anticancer agent in folk medicine. 展开更多
关键词 Pistacia integerrima Anti-tumor properties X-ray crystallography POM Molecular docking
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