Objective: This study evaluated the effectiveness of a 10-week exercise intervention in reducing depression and fatigue in women with postpartum depression. Design: A one-group pretest/ posttest quasi-experiment was c...Objective: This study evaluated the effectiveness of a 10-week exercise intervention in reducing depression and fatigue in women with postpartum depression. Design: A one-group pretest/ posttest quasi-experiment was conducted. Setting: A postpartum ward in a medical center in Taipei city was used. Participants: Nineteen women at 7 - 12 weeks postpartum with an Edinburgh Postnatal Depression Scale score ≥ 9 were recruited. Methods: The women participated in a postpartum exercise support program 1 hour per week for 10 weeks. The program was led by a professional coach;it integrated yoga, Pilates, elastic band exercise, low-intensity aerobics, and motherhood role experience sharing. Results: After the postpartum exercise support program intervention, depression scores decreased from 10.4 ± 3.29 to 7.80 ± 2.73 (t = 3.632, P = 0.003);fatigue scores decreased from 8.73 ± 5.02 to 5.40 ± 3.89 (t = 2.988, P = 0.010). Conclusion: PESP administered to women with postpartum depression appeared to benefit their psychological wellbeing.展开更多
This paper highlights the crucial role of Indonesia’s GNSS receiver network in advancing Equatorial Plasma Bubble(EPB)studies in Southeast and East Asia,as ionospheric irregularities within EPB can disrupt GNSS signa...This paper highlights the crucial role of Indonesia’s GNSS receiver network in advancing Equatorial Plasma Bubble(EPB)studies in Southeast and East Asia,as ionospheric irregularities within EPB can disrupt GNSS signals and degrade positioning accuracy.Managed by the Indonesian Geospatial Information Agency(BIG),the Indonesia Continuously Operating Reference Station(Ina-CORS)network comprises over 300 GNSS receivers spanning equatorial to southern low-latitude regions.Ina-CORS is uniquely situated to monitor EPB generation,zonal drift,and dissipation across Southeast Asia.We provide a practical tool for EPB research,by sharing two-dimensional rate of Total Electron Content(TEC)change index(ROTI)derived from this network.We generate ROTI maps with a 10-minute resolution,and samples from May 2024 are publicly available for further scientific research.Two preliminary findings from the ROTI maps of Ina-CORS are noteworthy.First,the Ina-CORS ROTI maps reveal that the irregularities within a broader EPB structure persist longer,increasing the potential for these irregularities to migrate farther eastward.Second,we demonstrate that combined ROTI maps from Ina-CORS and GNSS receivers in East Asia and Australia can be used to monitor the development of ionospheric irregularities in Southeast and East Asia.We have demonstrated the combined ROTI maps to capture the development of ionospheric irregularities in the Southeast/East Asian sector during the G5 Geomagnetic Storm on May 11,2024.We observed simultaneous ionospheric irregularities in Japan and Australia,respectively propagating northwestward and southwestward,before midnight,whereas Southeast Asia’s equatorial and low-latitude regions exhibited irregularities post-midnight.By sharing ROTI maps from Indonesia and integrating them with regional GNSS networks,researchers can conduct comprehensive EPB studies,enhancing the understanding of EPB behavior across Southeast and East Asia and contributing significantly to ionospheric research.展开更多
A unitized regenerative fuel cell(URFC)is a device that may function reversibly as either a fuel cell(FC)or water elec-trolysis(WE).An important component of this device is the Membrane electrode assembly(MEA).Therefo...A unitized regenerative fuel cell(URFC)is a device that may function reversibly as either a fuel cell(FC)or water elec-trolysis(WE).An important component of this device is the Membrane electrode assembly(MEA).Therefore,this study aimed to compare the performance outcomes of MEA using electrodes with single and three catalyst layers.This study measured Electrochemical Surface Area(ECSA),Electrochemical Impedance Spectroscopy(EIS),X-ray Diffraction analysis(XRD),and X-ray Fluorescence(XRF).Furthermore,the round-trip efficiency(RTE)of the MEA,as w ell as the performance in FC and WE mode,was measured.In comparison,The ECSA values of Pt-Ru/C and Pt/C with three catalyst layers were higher than the single catalyst layer.This result was supported by electrode characterization data for XRD and XRF.The respective electrical conductivity values of Pt-Ru/C and Pt/C with three catalyst layers are also higher than the single cata-lyst layer,and the performance of URFC using MEA with three catalyst layers has the highest value of RTE among the MEA performances of URFC,which is 100%at a current density of 4 mA·cm-2.展开更多
In the domain of knowledge graph embedding,conventional approaches typically transform entities and relations into continuous vector spaces.However,parameter efficiency becomes increasingly crucial when dealing with l...In the domain of knowledge graph embedding,conventional approaches typically transform entities and relations into continuous vector spaces.However,parameter efficiency becomes increasingly crucial when dealing with large-scale knowledge graphs that contain vast numbers of entities and relations.In particular,resource-intensive embeddings often lead to increased computational costs,and may limit scalability and adaptability in practical environ-ments,such as in low-resource settings or real-world applications.This paper explores an approach to knowledge graph representation learning that leverages small,reserved entities and relation sets for parameter-efficient embedding.We introduce a hierarchical attention network designed to refine and maximize the representational quality of embeddings by selectively focusing on these reserved sets,thereby reducing model complexity.Empirical assessments validate that our model achieves high performance on the benchmark dataset with fewer parameters and smaller embedding dimensions.The ablation studies further highlight the impact and contribution of each component in the proposed hierarchical attention structure.展开更多
BACKGROUND Hepatitis B and C and alcoholic liver disease are the principal causes of hepaticrelated morbidity and mortality.However,evidence of the associations between diabetes without the above risk factors and hepa...BACKGROUND Hepatitis B and C and alcoholic liver disease are the principal causes of hepaticrelated morbidity and mortality.However,evidence of the associations between diabetes without the above risk factors and hepatic-related study endpoints is not well understood.In addition,the effects of associated metabolic dysfunction and exercise on hepatic outcomes are still not clear.AIM To investigate the incidence and relative hazards of cirrhosis of the liver,hepato cellular carcinoma(HCC),hepatic-related complications and mortality in patients with type 2 diabetes(T2D)who were nonalcoholic and serologically negative for hepatitis B and C in Taiwan,China.METHODS A total of 33184 T2D patients and 648746 nondiabetic subjects selected from Taiwan’s,China adult preventive health care service were linked to various National Health Insurance databases,cancer registry,and death registry to identify cirrhosis of the liver,HCC,hepatic-related complications,and mortality.The Poisson assumption and Cox proportional hazard regression model were used to estimate the incidences and relative hazards of all hepatic-related study endpoints,respectively.We also compared the risk of hepatic outcomes stratified by age,sex,associated metabolic dysfunctions,and regular exercise between T2D patients and nondiabetic subjects.RESULTS Compared with nondiabetic subjects,T2D patients had a significantly greater incidence(6.32 vs 17.20 per 10000 person-years)and greater risk of cirrhosis of the liver[adjusted hazard ratio(aHR)1.45;95%CI:1.30-1.62].The aHRs for HCC,hepatic complications,and mortality were 1.81,1.87,and 2.08,respectively.An older age,male sex,obesity,hypertension,and dyslipidemia further increased the risks of all hepatic-related study endpoints,and regular exercise decreased the risk,irrespective of diabetes status.CONCLUSION Patients with T2D are at increased risk of cirrhosis of the liver,HCC,hepatic-related complications,and mortality,and associated metabolic dysfunctions provide additional hazard.Coordinated interprofessional care for high-risk T2D patients and diabetes education,with an emphasis on the importance of physical activity,are crucial for minimizing hepatic outcomes.展开更多
Multifocal epithelial hyperplasia(MEH),also known as Heck’s disease,is a rare and benign condition of the oral mucosa that is strongly associated with low-risk human papillomavirus(HPV)genotypes 13 and 32.This narrat...Multifocal epithelial hyperplasia(MEH),also known as Heck’s disease,is a rare and benign condition of the oral mucosa that is strongly associated with low-risk human papillomavirus(HPV)genotypes 13 and 32.This narrative review synthesizes recent findings regarding the epidemiology,viral mechanisms,clinical and histopathological features,diagnostic strategies-including molecular and immunohistochemical methods-and therapeutic approaches to MEH.This disease predominantly affects children and adolescents from Indigenous American countries,although cases have been increasingly reported in nonendemic regions.MEH manifests clinically as multiple,asymptomatic papules or nodules,typically exhibiting a characteristic cobblestone-like appearance.Histologically,it presents with epithelial hyperplasia,koilocytosis,and altered cytokeratin expression.Molecular techniques such as polymerase chain reaction and in situ hybridization are pivotal for accurate viral genotyping,while immunohistochemical markers such as CK4/13,Ki-67,and the absence of p16 can be useful adjuncts in differential diagnosis.Despite its self-limiting nature in most cases,treatment may be warranted in symptomatic or immunocompromised patients.This review highlights the need to improve diagnostic access,develop targeted vaccines,and implement public health strategies in vulnerable communities.It also highlights existing gaps in knowledge,particularly regarding host-virus interactions and the absence of standardized treatment protocols.展开更多
Gastric cancer is considered one of the most deadly tumors worldwide. Even with the decline in its incidence, the mortality rate of this disease has remained high, mainly due to its late diagnosis and to the lack of p...Gastric cancer is considered one of the most deadly tumors worldwide. Even with the decline in its incidence, the mortality rate of this disease has remained high, mainly due to its late diagnosis and to the lack of precise prognostic markers. The main purpose of this review is to present genetic, epigenetic and proteomic molecular markers that may be used in a diagnostic and prognostic manner and to discuss the pros and cons of each type of marker for improving clinical practice. In this sense, we observed that the use of genetic markers, especially mutations and polymorphisms, should be carefully considered, as they are strongly affected by ethnicity. Proteomic-based markers show promise, but the higher costs of the associated techniques con-tinue to make this approach expensive for routine use. Alternatively, epigenetic markers appear to be very promising, as they can be detected in bodily fluids as well as tissues. However, such markers must be used carefully because epigenetic changes may occur due to environmental factors and aging. Despite the advances in technology and its access, to date, there are few defined biomarkers of prognostic and diagnostic use for gastric tumors. Therefore, the use of a panel of several approaches(genetic, epigenetic and proteomic) should be considered the best alternative for clinical practice.展开更多
An experiment was conducted to evaluate whether supplementation with a probiotic could enhance digestion and reduce mortality in the volcano rabbit in captivity. Two enclosures at Chapultepec Zoo, Mexico（114 individu...An experiment was conducted to evaluate whether supplementation with a probiotic could enhance digestion and reduce mortality in the volcano rabbit in captivity. Two enclosures at Chapultepec Zoo, Mexico（114 individuals） were used in a crossover design（two periods of 60 days） with the following treatments： control group and supplementation with Saccharomyces cerevisiae（2×108 CFU/exhibit/day）. Supplementation with the probiotic negatively affected（P〈0.01） the digestibility of dry matter, organic matter, neutral detergent fiber（NDF） and energy. Mortality increased（P〈0.04） following supplementation with the probiotic（4.26% vs. 8.89%）, primarily in the juvenile rabbits. The results indicate that yeast supplementation in the volcano rabbit negatively affects digestion and mortality in captivity.展开更多
Objective: To identify the influences of local and regional climate phenomena on dengue transmission in Lahore District of Pakistan, from 2006 to 2014. Methods: Time-series models were applied to analyze associations ...Objective: To identify the influences of local and regional climate phenomena on dengue transmission in Lahore District of Pakistan, from 2006 to 2014. Methods: Time-series models were applied to analyze associations between reported cases of dengue and climatic parameters. The coherence trend of regional climate phenomena(IOD and ENSO) was evaluated with wavelet analysis. Results: The minimum temperature 4 months before the dengue outbreak played the most important role in the Lahore District(P=0.03). A NINO 3.4 index 9 months before the outbreaks exhibited a significant negative effect on dengue transmission(P=0.02). The IOD exhibited a synchronized pattern with dengue outbreak from 2010 to 2012. The ENSO effect(NINO 3.4 index) might have played a more important role after 2012. Conclusions: This study provides preliminary results of climate influences on dengue transmission in the Lahore District of Pakistan. An increasing dengue transmission risk accompanied by frequent climate changes should be noted. Integrating the influences of climate variability into disease prevention strategies should be considered by public health authorities.展开更多
AIM:To investigate the rates of polyp detection in a mixed risk population using standard definition (SDC) vs high definition colonoscopes (HDC).METHODS:This was a retrospective cohort comparative study of 3 colonosco...AIM:To investigate the rates of polyp detection in a mixed risk population using standard definition (SDC) vs high definition colonoscopes (HDC).METHODS:This was a retrospective cohort comparative study of 3 colonoscopists who each consecutively performed 150 SDC (307,200 pixel) and 150 HDC (792,576 pixels) in a community teaching hospital.RESULTS:A total of 900 colonoscopies were evaluated (mean age 56,46.8% men),450 with each resolution.Polyps of any type were detected in 46.0% of patients using SDC and 43.3% with HDC (P=0.42).There was no significant difference between the overall number of polyps,HDC (397) and SDC (410),detected among all patients examined,(P=0.73).One or more adenomatous polyps were detected in 24.2% of patients with HDC and 24.9% of patients with SDC colonoscopy (P=0.82).There was no significant difference between HDC (M=0.41) and SDC (M=0.42) regarding adenomatous polyp (P=0.88) or advanced adenoma (P=0.56) detection rate among all patients examined.CONCLUSION:HDC did not improve yield of adenomatous polyp,advanced adenoma or overall polyp detection in a population of individuals with mixed risk for colorectal cancer.展开更多
Rift Valley Fever (RVF) is an emerging, mosquito-borne disease with serious economical and negative implications on human and animal health. This study was conducted to verify the factors which influenced the spatial ...Rift Valley Fever (RVF) is an emerging, mosquito-borne disease with serious economical and negative implications on human and animal health. This study was conducted to verify the factors which influenced the spatial pattern of Rift Valley Fever occurrence and identified the high risk areas for the occurrence of the disease at Sinner State, Sudan. The normalized difference vegetation index (NDVI) derived from Moderate Resolution Imaging Spectroradiometer (MODIS) satellite and rainfall data in addition to the point data of RVF clinical cases in humans were used in this study. In order to identify the RVF high risk areas, remote sensing data and rainfall data were integrated in a GIS with other information including, soil type, water body, DEM (Digital Elevation Model), and animal routes and analyzed using Spatial Analysis tools. The information on clinical cases was used for verification. The Normalized Difference Vegetation Index (NDVI) was used to describe vegetation patterns of the study area by calculating the mean NDVI. The results of the study showed that, RVF risk increased with the increase in vegetation cover (high NDVI values), and increase in rainfall, which both provided suitable conditions for disease vectors breeding and a good indicator for RVF epizootics. The study concluded that, identification of high risk area for RVF disease improved the understanding of the spatial distribution of the disease and helped in locating the areas where disease was likely to be endemic and therefore preparedness measures should be taken. The identification represents the first step of prospective predictions of RVF outbreaks and provides a baseline for improved early warning, control, response planning, and mitigation. Further detailed studies are recommended in this domain.展开更多
Objective: To examine the effect of combination of Andrographis paniculata herb fraction(AHF) and Centella asiatica herb fraction(CHF) on PPAR γ and GLUT4 mRNA expression in 3 T3-L1 adipocyte, and its effect on insul...Objective: To examine the effect of combination of Andrographis paniculata herb fraction(AHF) and Centella asiatica herb fraction(CHF) on PPAR γ and GLUT4 mRNA expression in 3 T3-L1 adipocyte, and its effect on insulin-stimulated glucose uptake. Methods: 3 T3 L1 adipocyte cells were used to investigate gene expression of PPARy reverse transcription-polymerase chain reaction method. The γ and GLUT4 protein b adipocyte cells were differentiated by using insulin, dexamethasone and 3-isobutyl-1-methylxanthine from 3 T3-L1 cells. Pioglitazone, AHF, CHF and the combination of both herbs were evaluated on glucose uptake activity, PPAR γ and GLUT4 mRNA expressions in 3 T3-L1 adipocyte. Results: The results showed that combination of AHF at 30 μg/mL and CHF at 10 μg/mL could enhance insulin-stimulated glucose uptake. The combination also increased PPAR γ and GLUT4 mR NA expressions significantly in comparison to those of negative control(DMSO). These effects were equal in comparison to those of pioglitazone(0.02 μM) and its single extracts Conclusions: The combination of AHF and CHF can increase glucose uptake and insulin sensitivity through up-regulation of PPAR γ and GLUT4 mRNA expressions in 3 T3-L1 adipocyte.展开更多
The Karvonen formula, which is widely used to estimate exercise intensity, contains maximum heart rate, H Rmax, as a variable. This study employed pedaling experiments to assess which of the proposed formulas for calc...The Karvonen formula, which is widely used to estimate exercise intensity, contains maximum heart rate, H Rmax, as a variable. This study employed pedaling experiments to assess which of the proposed formulas for calculating H Rmaxwas the most suitable for use with the Karvonen formula. First, two kinds of experiments involving an ergometer were performed: an all-in-one-day experiment that tested eight pedaling loads in one day, and a one-load-per-day experiment that tested one load per day for eight days.A comparison of the data on 7 subjects showed that the all-in-one-day type of experiment was better for assessing H Rmaxformulas,at least for the load levels tested in our experiments. A statistical analysis of the experimental data on 47 subjects showed two of the H Rmaxformulas to be suitable for use in the Karvonen formula to estimate exercise intensity for males in their 20 s. In addition, the physical characteristics of a person having the greatest impact on exercise intensity were determined.展开更多
In 2019, Indonesia was ranked second with 619,840.03 carbon emissions, after India. Therefore, the Indonesian government issued a zero emission plan in 2022 and encouraged Indonesians to purchase electric vehicles, st...In 2019, Indonesia was ranked second with 619,840.03 carbon emissions, after India. Therefore, the Indonesian government issued a zero emission plan in 2022 and encouraged Indonesians to purchase electric vehicles, striving to achieve zero emissions by 2060. Facing the huge potential market for the development of electric vehicles in Indonesia, the Chinese brand Wuling took this opportunity to launch its first electric vehicle, Wuling Air EV, in Indonesia. This study aims to analyze the influence of the brand image of Wuling electric vehicles, brand awareness, country of origin and perceived risk on the purchase intention of Indonesian consumers. Data collection in this study was carried out through offline and online questionnaires which were distributed to 150 respondents who met the research criteria in the JABODETABEK area, and they all owned cars and had driving experience. Partial Least Squares-Structural Equation Modeling (PLS-SEM) was adopted for data analysis. The results of this study indicate that country of origin, perceived risk, and brand image have a significant effect on consumer purchase intention. In addition, perceived risk also has a significant positive impact on brand image. However, the influence of country of origin and brand awareness has no significant effect on brand image.展开更多
1.Peculiarity of the BRICS emerging economies Since the late 1980s,accelerated globalization has provided economic growth opportunities in mature and emerging economies.The rapidly developing nations of Brazil,Russia,...1.Peculiarity of the BRICS emerging economies Since the late 1980s,accelerated globalization has provided economic growth opportunities in mature and emerging economies.The rapidly developing nations of Brazil,Russia,India,China,and South Africa(BRICS nations)have a combined economic output that makes BRICS countries the world's major emerging economies.展开更多
The Langat River Basin in Malaysia is vulnerable to soil erosion risks because of its exposure to intensive land use activities and its topography,which primarily consists of steep slopes and mountainous areas.Further...The Langat River Basin in Malaysia is vulnerable to soil erosion risks because of its exposure to intensive land use activities and its topography,which primarily consists of steep slopes and mountainous areas.Furthermore,climate change frequently exposes this basin to drought,which negatively affects soil and water conservation.However,recent studies have rarely shown how soil reacts to drought,such as soil erosion.Therefore,the purpose of this study is to evaluate the relationship between drought and soil erosion in the Langat River Basin.We analyzed drought indices using Landsat 8 satellite images in November 2021,and created the normalized differential water index(NDWI)via Landsat 8 data to produce a drought map.We used the revised universal soil loss equation(RUSLE)model to predict soil erosion.We verified an association between the NDWI and soil erosion data using a correlation analysis.The results revealed that the southern and northern regions of the study area experienced drought events.We predicted an average annual soil erosion of approximately 58.11 t/(hm^(2)·a).Analysis of the association between the NDWI and soil erosion revealed a strong positive correlation,with a Pearson correlation coefficient of 0.86.We assumed that the slope length and steepness factor was the primary contributor to soil erosion in the study area.As a result,these findings can help authorities plan effective measures to reduce the impacts of drought and soil erosion in the future.展开更多
Polymer clay nanocomposites (PCN) materials are industrially applied because of their unique properties. However many of their physical and chemical properties have not been determined. The formed structures of polyme...Polymer clay nanocomposites (PCN) materials are industrially applied because of their unique properties. However many of their physical and chemical properties have not been determined. The formed structures of polymer/clay nanocomposite depend on the nature of interactions between polymer chains and clay platelets. According to the possible modes of interactions between polymer matrix and clay sheets, these nanocomposites can be classified into: intercalated, flocculated and exfoliated nanocomposites. In this work, the morphology of the nanocomposite was studied using X-ray diffraction (XRD) and nanoscaning electron microscopy (NSEM). XRD and NSEM measurements confirmed the intercalation between poly(vinyl alcohol) chains and cloisite®20A sheets. Because of the intercalation between the clay platelets and the PVA chains, as the clay concentration increases as the band intensities in FT-IR spectra increase. On the other hand, the XRD did not provide clear shift of any of the clay peaks for PVA/cloisite® 10A nanocomposites and confirm the non-intercalation between PVA matrix and cloisite®10A platelets. The relative intercalation (RI) of PVA/Cloisite®20A nanocomposites declined with increase in the clay loadings. In contrast, for PVA/Cloisite®10A, RI values slightly increased with increasing the clay loading.展开更多
Using the conflict principle of the Stroop task, “effect of interference in color naming”, the present study proposes to create a computational version of the emotional Stroop task, called TREFACE, for its acronyms ...Using the conflict principle of the Stroop task, “effect of interference in color naming”, the present study proposes to create a computational version of the emotional Stroop task, called TREFACE, for its acronyms in Portuguese “Teste de Reconhecimento de Expressões Faciais com Conflito Emocional” (Facial Expression Recognition Test with Emotional Conflict). In this protocol, four fixed styles of presentation were generated according to the condition: Congruent Word Reading, Incongruent Word Reading, Congruent Recognition of Face Expression and Incongruent Recognition of Face Expression, counterbalanced in terms of each facial expression, word and gender of the photo character. Forty-two healthy volunteers completed the task. Results revealed that a task associated with word reading allows better performance than a task associated with face recognition. It was also identified that in the congruent condition, there is an advantage in terms of the correct responses. Additionally, the data regarding recognition of face expression showed greater difficulty when the image was not congruent with the word. In general, the results suggest that the emotional attribute can compromise the ability to recognize the faces, reaching the functioning of mechanisms such as cognitive control and regulation of emotions. Thus, the TREFACE paradigm can be considered a good assessment tool for monitoring emotional conflict, in addition to presenting itself as a new instrument in Portuguese language for assessing emotional working memory in healthy individuals and, eventually, in different pathologies that affect the functioning of cortical areas related to executive functions.展开更多
Waste is the main problem for the environment.Handling waste for various useful applications has a benefit for the future.This work has been studied for handling pineapple peel waste to make composite film bacterial c...Waste is the main problem for the environment.Handling waste for various useful applications has a benefit for the future.This work has been studied for handling pineapple peel waste to make composite film bacterial cellulose nanocomposite membrane(BCNM)with addition graphite nanoplatelet(GNP).The concentration of GNP in the membrane influence the membrane properties.The bacterial cellulose(BC)pellicle was synthesized by using media from pineapple peel waste extract.BC pellicle is cleaned with water and NaOH solution to be free from impactors.BCNM is synthesized through the mechanical disintegration stage.The results of disintegration using high pressure homogenizer at 150 bar and five cycles.BCNM/GNP is synthesized with varying addition of GNP of 2.5,5.0,10 and 100 wt%of dry bacterial nanocellulose(BNC).The BC and GNP solution were dried in an oven for 14 h at 80℃.BCNM morphology was observed using SEM.GNP is dispersed and distributed in the BC matrix as reinforcement.FTIR analysis shows many peaks of BNC less pronounced with increasing of GNP.The higher concentration of GNP,the rougher of BCNM.The optimum tensile strength of BCNM was achieved after addition GNP of 2.5 wt%.展开更多
文摘Objective: This study evaluated the effectiveness of a 10-week exercise intervention in reducing depression and fatigue in women with postpartum depression. Design: A one-group pretest/ posttest quasi-experiment was conducted. Setting: A postpartum ward in a medical center in Taipei city was used. Participants: Nineteen women at 7 - 12 weeks postpartum with an Edinburgh Postnatal Depression Scale score ≥ 9 were recruited. Methods: The women participated in a postpartum exercise support program 1 hour per week for 10 weeks. The program was led by a professional coach;it integrated yoga, Pilates, elastic band exercise, low-intensity aerobics, and motherhood role experience sharing. Results: After the postpartum exercise support program intervention, depression scores decreased from 10.4 ± 3.29 to 7.80 ± 2.73 (t = 3.632, P = 0.003);fatigue scores decreased from 8.73 ± 5.02 to 5.40 ± 3.89 (t = 2.988, P = 0.010). Conclusion: PESP administered to women with postpartum depression appeared to benefit their psychological wellbeing.
基金JSPS KAKENHI Grant Number16H06286 supports global GNSS ionospheric maps (TEC,ROTI,and detrended TEC maps) developed by the Institute for SpaceEarth Environmental Research (ISEE) of Nagoya Universitysupport of the 2024 JASSO Follow-up Research Fellowship Program for a 90-day visiting research at the Institute for Space-Earth Environmental Research (ISEE),Nagoya University+3 种基金the support received from Telkom University under the“Skema Penelitian Terapan Periode I Tahun Anggaran 2024”the Memorandum of Understanding for Research Collaboration on Regional Ionospheric Observation (No:092/SAM3/TE-DEK/2021)the National Institute of Information and Communications Technology (NICT) International Exchange Program 2024-2025(No.2024-007)support for a one-year visiting research at Hokkaido University
文摘This paper highlights the crucial role of Indonesia’s GNSS receiver network in advancing Equatorial Plasma Bubble(EPB)studies in Southeast and East Asia,as ionospheric irregularities within EPB can disrupt GNSS signals and degrade positioning accuracy.Managed by the Indonesian Geospatial Information Agency(BIG),the Indonesia Continuously Operating Reference Station(Ina-CORS)network comprises over 300 GNSS receivers spanning equatorial to southern low-latitude regions.Ina-CORS is uniquely situated to monitor EPB generation,zonal drift,and dissipation across Southeast Asia.We provide a practical tool for EPB research,by sharing two-dimensional rate of Total Electron Content(TEC)change index(ROTI)derived from this network.We generate ROTI maps with a 10-minute resolution,and samples from May 2024 are publicly available for further scientific research.Two preliminary findings from the ROTI maps of Ina-CORS are noteworthy.First,the Ina-CORS ROTI maps reveal that the irregularities within a broader EPB structure persist longer,increasing the potential for these irregularities to migrate farther eastward.Second,we demonstrate that combined ROTI maps from Ina-CORS and GNSS receivers in East Asia and Australia can be used to monitor the development of ionospheric irregularities in Southeast and East Asia.We have demonstrated the combined ROTI maps to capture the development of ionospheric irregularities in the Southeast/East Asian sector during the G5 Geomagnetic Storm on May 11,2024.We observed simultaneous ionospheric irregularities in Japan and Australia,respectively propagating northwestward and southwestward,before midnight,whereas Southeast Asia’s equatorial and low-latitude regions exhibited irregularities post-midnight.By sharing ROTI maps from Indonesia and integrating them with regional GNSS networks,researchers can conduct comprehensive EPB studies,enhancing the understanding of EPB behavior across Southeast and East Asia and contributing significantly to ionospheric research.
基金support from the Ministry of Higher Education Malaysia under grant HICOE-2023-005.
文摘A unitized regenerative fuel cell(URFC)is a device that may function reversibly as either a fuel cell(FC)or water elec-trolysis(WE).An important component of this device is the Membrane electrode assembly(MEA).Therefore,this study aimed to compare the performance outcomes of MEA using electrodes with single and three catalyst layers.This study measured Electrochemical Surface Area(ECSA),Electrochemical Impedance Spectroscopy(EIS),X-ray Diffraction analysis(XRD),and X-ray Fluorescence(XRF).Furthermore,the round-trip efficiency(RTE)of the MEA,as w ell as the performance in FC and WE mode,was measured.In comparison,The ECSA values of Pt-Ru/C and Pt/C with three catalyst layers were higher than the single catalyst layer.This result was supported by electrode characterization data for XRD and XRF.The respective electrical conductivity values of Pt-Ru/C and Pt/C with three catalyst layers are also higher than the single cata-lyst layer,and the performance of URFC using MEA with three catalyst layers has the highest value of RTE among the MEA performances of URFC,which is 100%at a current density of 4 mA·cm-2.
基金supported by the National Science and Technology Council(NSTC),Taiwan,under Grants Numbers 112-2622-E-029-009 and 112-2221-E-029-019.
文摘In the domain of knowledge graph embedding,conventional approaches typically transform entities and relations into continuous vector spaces.However,parameter efficiency becomes increasingly crucial when dealing with large-scale knowledge graphs that contain vast numbers of entities and relations.In particular,resource-intensive embeddings often lead to increased computational costs,and may limit scalability and adaptability in practical environ-ments,such as in low-resource settings or real-world applications.This paper explores an approach to knowledge graph representation learning that leverages small,reserved entities and relation sets for parameter-efficient embedding.We introduce a hierarchical attention network designed to refine and maximize the representational quality of embeddings by selectively focusing on these reserved sets,thereby reducing model complexity.Empirical assessments validate that our model achieves high performance on the benchmark dataset with fewer parameters and smaller embedding dimensions.The ablation studies further highlight the impact and contribution of each component in the proposed hierarchical attention structure.
基金Supported by The Far Eastern Memorial Hospital,No.FEMH-2022-C-015,No.FEMH-2022-C-017 and No.FEMH-2023-C-082.
文摘BACKGROUND Hepatitis B and C and alcoholic liver disease are the principal causes of hepaticrelated morbidity and mortality.However,evidence of the associations between diabetes without the above risk factors and hepatic-related study endpoints is not well understood.In addition,the effects of associated metabolic dysfunction and exercise on hepatic outcomes are still not clear.AIM To investigate the incidence and relative hazards of cirrhosis of the liver,hepato cellular carcinoma(HCC),hepatic-related complications and mortality in patients with type 2 diabetes(T2D)who were nonalcoholic and serologically negative for hepatitis B and C in Taiwan,China.METHODS A total of 33184 T2D patients and 648746 nondiabetic subjects selected from Taiwan’s,China adult preventive health care service were linked to various National Health Insurance databases,cancer registry,and death registry to identify cirrhosis of the liver,HCC,hepatic-related complications,and mortality.The Poisson assumption and Cox proportional hazard regression model were used to estimate the incidences and relative hazards of all hepatic-related study endpoints,respectively.We also compared the risk of hepatic outcomes stratified by age,sex,associated metabolic dysfunctions,and regular exercise between T2D patients and nondiabetic subjects.RESULTS Compared with nondiabetic subjects,T2D patients had a significantly greater incidence(6.32 vs 17.20 per 10000 person-years)and greater risk of cirrhosis of the liver[adjusted hazard ratio(aHR)1.45;95%CI:1.30-1.62].The aHRs for HCC,hepatic complications,and mortality were 1.81,1.87,and 2.08,respectively.An older age,male sex,obesity,hypertension,and dyslipidemia further increased the risks of all hepatic-related study endpoints,and regular exercise decreased the risk,irrespective of diabetes status.CONCLUSION Patients with T2D are at increased risk of cirrhosis of the liver,HCC,hepatic-related complications,and mortality,and associated metabolic dysfunctions provide additional hazard.Coordinated interprofessional care for high-risk T2D patients and diabetes education,with an emphasis on the importance of physical activity,are crucial for minimizing hepatic outcomes.
文摘Multifocal epithelial hyperplasia(MEH),also known as Heck’s disease,is a rare and benign condition of the oral mucosa that is strongly associated with low-risk human papillomavirus(HPV)genotypes 13 and 32.This narrative review synthesizes recent findings regarding the epidemiology,viral mechanisms,clinical and histopathological features,diagnostic strategies-including molecular and immunohistochemical methods-and therapeutic approaches to MEH.This disease predominantly affects children and adolescents from Indigenous American countries,although cases have been increasingly reported in nonendemic regions.MEH manifests clinically as multiple,asymptomatic papules or nodules,typically exhibiting a characteristic cobblestone-like appearance.Histologically,it presents with epithelial hyperplasia,koilocytosis,and altered cytokeratin expression.Molecular techniques such as polymerase chain reaction and in situ hybridization are pivotal for accurate viral genotyping,while immunohistochemical markers such as CK4/13,Ki-67,and the absence of p16 can be useful adjuncts in differential diagnosis.Despite its self-limiting nature in most cases,treatment may be warranted in symptomatic or immunocompromised patients.This review highlights the need to improve diagnostic access,develop targeted vaccines,and implement public health strategies in vulnerable communities.It also highlights existing gaps in knowledge,particularly regarding host-virus interactions and the absence of standardized treatment protocols.
文摘Gastric cancer is considered one of the most deadly tumors worldwide. Even with the decline in its incidence, the mortality rate of this disease has remained high, mainly due to its late diagnosis and to the lack of precise prognostic markers. The main purpose of this review is to present genetic, epigenetic and proteomic molecular markers that may be used in a diagnostic and prognostic manner and to discuss the pros and cons of each type of marker for improving clinical practice. In this sense, we observed that the use of genetic markers, especially mutations and polymorphisms, should be carefully considered, as they are strongly affected by ethnicity. Proteomic-based markers show promise, but the higher costs of the associated techniques con-tinue to make this approach expensive for routine use. Alternatively, epigenetic markers appear to be very promising, as they can be detected in bodily fluids as well as tissues. However, such markers must be used carefully because epigenetic changes may occur due to environmental factors and aging. Despite the advances in technology and its access, to date, there are few defined biomarkers of prognostic and diagnostic use for gastric tumors. Therefore, the use of a panel of several approaches(genetic, epigenetic and proteomic) should be considered the best alternative for clinical practice.
文摘An experiment was conducted to evaluate whether supplementation with a probiotic could enhance digestion and reduce mortality in the volcano rabbit in captivity. Two enclosures at Chapultepec Zoo, Mexico（114 individuals） were used in a crossover design（two periods of 60 days） with the following treatments： control group and supplementation with Saccharomyces cerevisiae（2×108 CFU/exhibit/day）. Supplementation with the probiotic negatively affected（P〈0.01） the digestibility of dry matter, organic matter, neutral detergent fiber（NDF） and energy. Mortality increased（P〈0.04） following supplementation with the probiotic（4.26% vs. 8.89%）, primarily in the juvenile rabbits. The results indicate that yeast supplementation in the volcano rabbit negatively affects digestion and mortality in captivity.
基金funded by the Taiwan Ministry of Science and Technology(MOST 104-2119-M-038-002)the Taipei Medical University(TMU101-AE1-B62)
文摘Objective: To identify the influences of local and regional climate phenomena on dengue transmission in Lahore District of Pakistan, from 2006 to 2014. Methods: Time-series models were applied to analyze associations between reported cases of dengue and climatic parameters. The coherence trend of regional climate phenomena(IOD and ENSO) was evaluated with wavelet analysis. Results: The minimum temperature 4 months before the dengue outbreak played the most important role in the Lahore District(P=0.03). A NINO 3.4 index 9 months before the outbreaks exhibited a significant negative effect on dengue transmission(P=0.02). The IOD exhibited a synchronized pattern with dengue outbreak from 2010 to 2012. The ENSO effect(NINO 3.4 index) might have played a more important role after 2012. Conclusions: This study provides preliminary results of climate influences on dengue transmission in the Lahore District of Pakistan. An increasing dengue transmission risk accompanied by frequent climate changes should be noted. Integrating the influences of climate variability into disease prevention strategies should be considered by public health authorities.
基金Supported by Cleveland Clinic Florida Institution Review Committee
文摘AIM:To investigate the rates of polyp detection in a mixed risk population using standard definition (SDC) vs high definition colonoscopes (HDC).METHODS:This was a retrospective cohort comparative study of 3 colonoscopists who each consecutively performed 150 SDC (307,200 pixel) and 150 HDC (792,576 pixels) in a community teaching hospital.RESULTS:A total of 900 colonoscopies were evaluated (mean age 56,46.8% men),450 with each resolution.Polyps of any type were detected in 46.0% of patients using SDC and 43.3% with HDC (P=0.42).There was no significant difference between the overall number of polyps,HDC (397) and SDC (410),detected among all patients examined,(P=0.73).One or more adenomatous polyps were detected in 24.2% of patients with HDC and 24.9% of patients with SDC colonoscopy (P=0.82).There was no significant difference between HDC (M=0.41) and SDC (M=0.42) regarding adenomatous polyp (P=0.88) or advanced adenoma (P=0.56) detection rate among all patients examined.CONCLUSION:HDC did not improve yield of adenomatous polyp,advanced adenoma or overall polyp detection in a population of individuals with mixed risk for colorectal cancer.
文摘Rift Valley Fever (RVF) is an emerging, mosquito-borne disease with serious economical and negative implications on human and animal health. This study was conducted to verify the factors which influenced the spatial pattern of Rift Valley Fever occurrence and identified the high risk areas for the occurrence of the disease at Sinner State, Sudan. The normalized difference vegetation index (NDVI) derived from Moderate Resolution Imaging Spectroradiometer (MODIS) satellite and rainfall data in addition to the point data of RVF clinical cases in humans were used in this study. In order to identify the RVF high risk areas, remote sensing data and rainfall data were integrated in a GIS with other information including, soil type, water body, DEM (Digital Elevation Model), and animal routes and analyzed using Spatial Analysis tools. The information on clinical cases was used for verification. The Normalized Difference Vegetation Index (NDVI) was used to describe vegetation patterns of the study area by calculating the mean NDVI. The results of the study showed that, RVF risk increased with the increase in vegetation cover (high NDVI values), and increase in rainfall, which both provided suitable conditions for disease vectors breeding and a good indicator for RVF epizootics. The study concluded that, identification of high risk area for RVF disease improved the understanding of the spatial distribution of the disease and helped in locating the areas where disease was likely to be endemic and therefore preparedness measures should be taken. The identification represents the first step of prospective predictions of RVF outbreaks and provides a baseline for improved early warning, control, response planning, and mitigation. Further detailed studies are recommended in this domain.
基金supported by the Ministry of Research and Technology and Higher Education of the Republic of Indonesia(RISTEKDIKTI)through "Hibah Unggulan Perguruan Tinggi 2017"
文摘Objective: To examine the effect of combination of Andrographis paniculata herb fraction(AHF) and Centella asiatica herb fraction(CHF) on PPAR γ and GLUT4 mRNA expression in 3 T3-L1 adipocyte, and its effect on insulin-stimulated glucose uptake. Methods: 3 T3 L1 adipocyte cells were used to investigate gene expression of PPARy reverse transcription-polymerase chain reaction method. The γ and GLUT4 protein b adipocyte cells were differentiated by using insulin, dexamethasone and 3-isobutyl-1-methylxanthine from 3 T3-L1 cells. Pioglitazone, AHF, CHF and the combination of both herbs were evaluated on glucose uptake activity, PPAR γ and GLUT4 mRNA expressions in 3 T3-L1 adipocyte. Results: The results showed that combination of AHF at 30 μg/mL and CHF at 10 μg/mL could enhance insulin-stimulated glucose uptake. The combination also increased PPAR γ and GLUT4 mR NA expressions significantly in comparison to those of negative control(DMSO). These effects were equal in comparison to those of pioglitazone(0.02 μM) and its single extracts Conclusions: The combination of AHF and CHF can increase glucose uptake and insulin sensitivity through up-regulation of PPAR γ and GLUT4 mRNA expressions in 3 T3-L1 adipocyte.
基金supported by Health Science Center Foundation,Japan
文摘The Karvonen formula, which is widely used to estimate exercise intensity, contains maximum heart rate, H Rmax, as a variable. This study employed pedaling experiments to assess which of the proposed formulas for calculating H Rmaxwas the most suitable for use with the Karvonen formula. First, two kinds of experiments involving an ergometer were performed: an all-in-one-day experiment that tested eight pedaling loads in one day, and a one-load-per-day experiment that tested one load per day for eight days.A comparison of the data on 7 subjects showed that the all-in-one-day type of experiment was better for assessing H Rmaxformulas,at least for the load levels tested in our experiments. A statistical analysis of the experimental data on 47 subjects showed two of the H Rmaxformulas to be suitable for use in the Karvonen formula to estimate exercise intensity for males in their 20 s. In addition, the physical characteristics of a person having the greatest impact on exercise intensity were determined.
文摘In 2019, Indonesia was ranked second with 619,840.03 carbon emissions, after India. Therefore, the Indonesian government issued a zero emission plan in 2022 and encouraged Indonesians to purchase electric vehicles, striving to achieve zero emissions by 2060. Facing the huge potential market for the development of electric vehicles in Indonesia, the Chinese brand Wuling took this opportunity to launch its first electric vehicle, Wuling Air EV, in Indonesia. This study aims to analyze the influence of the brand image of Wuling electric vehicles, brand awareness, country of origin and perceived risk on the purchase intention of Indonesian consumers. Data collection in this study was carried out through offline and online questionnaires which were distributed to 150 respondents who met the research criteria in the JABODETABEK area, and they all owned cars and had driving experience. Partial Least Squares-Structural Equation Modeling (PLS-SEM) was adopted for data analysis. The results of this study indicate that country of origin, perceived risk, and brand image have a significant effect on consumer purchase intention. In addition, perceived risk also has a significant positive impact on brand image. However, the influence of country of origin and brand awareness has no significant effect on brand image.
基金partially funded by Grant OI 175 014 of the Ministry of Education Science and Technological Development of The Republic of Serbia
文摘1.Peculiarity of the BRICS emerging economies Since the late 1980s,accelerated globalization has provided economic growth opportunities in mature and emerging economies.The rapidly developing nations of Brazil,Russia,India,China,and South Africa(BRICS nations)have a combined economic output that makes BRICS countries the world's major emerging economies.
文摘The Langat River Basin in Malaysia is vulnerable to soil erosion risks because of its exposure to intensive land use activities and its topography,which primarily consists of steep slopes and mountainous areas.Furthermore,climate change frequently exposes this basin to drought,which negatively affects soil and water conservation.However,recent studies have rarely shown how soil reacts to drought,such as soil erosion.Therefore,the purpose of this study is to evaluate the relationship between drought and soil erosion in the Langat River Basin.We analyzed drought indices using Landsat 8 satellite images in November 2021,and created the normalized differential water index(NDWI)via Landsat 8 data to produce a drought map.We used the revised universal soil loss equation(RUSLE)model to predict soil erosion.We verified an association between the NDWI and soil erosion data using a correlation analysis.The results revealed that the southern and northern regions of the study area experienced drought events.We predicted an average annual soil erosion of approximately 58.11 t/(hm^(2)·a).Analysis of the association between the NDWI and soil erosion revealed a strong positive correlation,with a Pearson correlation coefficient of 0.86.We assumed that the slope length and steepness factor was the primary contributor to soil erosion in the study area.As a result,these findings can help authorities plan effective measures to reduce the impacts of drought and soil erosion in the future.
文摘Polymer clay nanocomposites (PCN) materials are industrially applied because of their unique properties. However many of their physical and chemical properties have not been determined. The formed structures of polymer/clay nanocomposite depend on the nature of interactions between polymer chains and clay platelets. According to the possible modes of interactions between polymer matrix and clay sheets, these nanocomposites can be classified into: intercalated, flocculated and exfoliated nanocomposites. In this work, the morphology of the nanocomposite was studied using X-ray diffraction (XRD) and nanoscaning electron microscopy (NSEM). XRD and NSEM measurements confirmed the intercalation between poly(vinyl alcohol) chains and cloisite®20A sheets. Because of the intercalation between the clay platelets and the PVA chains, as the clay concentration increases as the band intensities in FT-IR spectra increase. On the other hand, the XRD did not provide clear shift of any of the clay peaks for PVA/cloisite® 10A nanocomposites and confirm the non-intercalation between PVA matrix and cloisite®10A platelets. The relative intercalation (RI) of PVA/Cloisite®20A nanocomposites declined with increase in the clay loadings. In contrast, for PVA/Cloisite®10A, RI values slightly increased with increasing the clay loading.
文摘Using the conflict principle of the Stroop task, “effect of interference in color naming”, the present study proposes to create a computational version of the emotional Stroop task, called TREFACE, for its acronyms in Portuguese “Teste de Reconhecimento de Expressões Faciais com Conflito Emocional” (Facial Expression Recognition Test with Emotional Conflict). In this protocol, four fixed styles of presentation were generated according to the condition: Congruent Word Reading, Incongruent Word Reading, Congruent Recognition of Face Expression and Incongruent Recognition of Face Expression, counterbalanced in terms of each facial expression, word and gender of the photo character. Forty-two healthy volunteers completed the task. Results revealed that a task associated with word reading allows better performance than a task associated with face recognition. It was also identified that in the congruent condition, there is an advantage in terms of the correct responses. Additionally, the data regarding recognition of face expression showed greater difficulty when the image was not congruent with the word. In general, the results suggest that the emotional attribute can compromise the ability to recognize the faces, reaching the functioning of mechanisms such as cognitive control and regulation of emotions. Thus, the TREFACE paradigm can be considered a good assessment tool for monitoring emotional conflict, in addition to presenting itself as a new instrument in Portuguese language for assessing emotional working memory in healthy individuals and, eventually, in different pathologies that affect the functioning of cortical areas related to executive functions.
基金the Universitas Negeri Malang through the PNBP Research Grant 2021 with PUI/CAMRY scheme by Contract No.5.3.837/UN32.14.1/LT2021.
文摘Waste is the main problem for the environment.Handling waste for various useful applications has a benefit for the future.This work has been studied for handling pineapple peel waste to make composite film bacterial cellulose nanocomposite membrane(BCNM)with addition graphite nanoplatelet(GNP).The concentration of GNP in the membrane influence the membrane properties.The bacterial cellulose(BC)pellicle was synthesized by using media from pineapple peel waste extract.BC pellicle is cleaned with water and NaOH solution to be free from impactors.BCNM is synthesized through the mechanical disintegration stage.The results of disintegration using high pressure homogenizer at 150 bar and five cycles.BCNM/GNP is synthesized with varying addition of GNP of 2.5,5.0,10 and 100 wt%of dry bacterial nanocellulose(BNC).The BC and GNP solution were dried in an oven for 14 h at 80℃.BCNM morphology was observed using SEM.GNP is dispersed and distributed in the BC matrix as reinforcement.FTIR analysis shows many peaks of BNC less pronounced with increasing of GNP.The higher concentration of GNP,the rougher of BCNM.The optimum tensile strength of BCNM was achieved after addition GNP of 2.5 wt%.
