Objective This study aimed to examine and propagate the medication experience and group formula of traditional Chinese medicine(TCM)Master XIONG Jibo in diagnosing and treat-ing arthralgia syndrome(AS)through data min...Objective This study aimed to examine and propagate the medication experience and group formula of traditional Chinese medicine(TCM)Master XIONG Jibo in diagnosing and treat-ing arthralgia syndrome(AS)through data mining.Methods Data of outpatient cases of Professor XIONG Jibo were collected from January 1,2014 to December 31,2018,along with cases recorded in A Real Famous Traditional Chinese Medicine Doctor:XIONG Jibo's Clinical Medical Record 1,which was published in December 2019.The five variables collected from the patients’data were TCM diagnostic information,TCM and western medicine diagnoses,syndrome,treatment,and prescription.A database was established for the collected data with Excel.Using the Python environment,a custom-ized modified natural language processing(NLP)model for the diagnosis and treatment of AS by Professor XIONG Jibo was established to preprocess the data and to analyze the word cloud.Frequency analysis,association rule analysis,cluster analysis,and visual analysis of AS cases were performed based on the Traditional Chinese Medicine Inheritance Computing Platform(V3.0)and RStudio(V4.0.3).Results A total of 610 medical records of Professor XIONG Jibo were collected from the case database.A total of 103 medical records were included after data screening criteria,which comprised 187 times(45 kinds)of prescriptions and 1506 times(125 kinds)of Chinese herbs.The main related meridians were the liver,spleen,and kidney meridians.The properties of Chinese herbs used most were mainly warm,flat,and cold,while the flavors of herbs were mainly bitter,pungent,and sweet.The main patterns of AS included the damp heat,phlegm stasis,and neck arthralgia.The most commonly used herbs for AS were Chuanniuxi(Cyathu-lae Radix),Huangbo(Phellodendri Chinensis Cortex),Cangzhu(Atractylodis Rhizoma),Qinjiao(Gentianae Macrophyllae Radix),Gancao(Glycyrrhizae Radix et Rhizoma),Huangqi(Astragali Radix),and Chuanxiong(Chuanxiong Rhizoma).The most common effect of the herbs was“promoting blood circulation and removing blood stasis”,followed by“supple-menting deficiency(Qi supplementing,blood supplementing,and Yang supplementing)”,and“dispelling wind and dampness”.The data were analyzed with the support≥15%and con-fidence=100%,and after de-duplication,five second-order association rules,39 third-order association rules,39 fourth-order association rules,and two fifth-order association rules were identified.The top-ranking association rules of each were“Cangzhu(Atractylodis Rhizoma)→Huangbo(Phellodendri Chinensis Cortex)”“Cangzhu(Atractylodis Rhizoma)+Chuanniuxi(Cyathulae Radix)→Huangbo(Phellodendri Chinensis Cortex)”“Chuanniuxi(Cyathulae Radix)+Danggui(Angelicae Sinensis Radix)+Gancao(Glycyrrhizae Radix et Rhizoma)→Qinjiao(Gentianae Macrophyllae Radix)”and“Chuanniuxi(Cyathulae Radix)+Danggui(Angelicae Sinensis Radix)+Gancao(Glycyrrhizae Radix et Rhizoma)+Huangbo(Phello-dendri Chinensis Cortex)→Qinjiao(Gentianae Macrophyllae Radix)”,respectively.Five clusters were obtained using cluster analysis of the top 30 herbs.The herbs were mainly dry-ing dampness,supplementing Qi,and promoting blood circulation.The main prescriptions of AS were Ermiao San(二妙散),Gegen Jianghuang San(葛根姜黄散),and Huangqi Chongteng Yin(黄芪虫藤饮).The herbs of core prescription included Cangzhu(Atractylodis Rhizoma),Chuanniuxi(Cyathulae Radix),Gancao(Glycyrrhizae Radix et Rhizoma),Huangbo(Phellodendri Chinensis Cortex),Mugua(Chaenomelis Fructus),Qinjiao(Gentianae Macro-phyllae Radix),Danggui(Angelicae Sinensis Radix),and Yiyiren(Coicis Semen).Conclusion Clearing heat and dampness,relieving collaterals and pain,and invigorating Qi and blood are the most commonly used therapies for the treatment of AS by Professor XIONG Jibo.Additionally,customized NLP model could improve the efficiency of data mining in TCM.展开更多
<strong>Background:</strong> To ensure quality and relevance of Postgraduate Programs are a commitment of the National Quality Postgraduate Programs (PNPC), and those from UNAM. Then, the self-evaluation o...<strong>Background:</strong> To ensure quality and relevance of Postgraduate Programs are a commitment of the National Quality Postgraduate Programs (PNPC), and those from UNAM. Then, the self-evaluation of the Masters in Nursing Program (PME) is necessary for it to be part of the PNPC. This study focuses on self-evaluation of implementation mechanisms to assure effective communication and collaboration with and among graduated alumni. <strong>Methods:</strong> The research was qualitative, exploratory and descriptive. An informed consent was signed by four informants, graduated from the seventeenth generation of PME. Data collection from a focal group and descriptive data analysis by atlas.ti from guidance questions that were contrasted with the scale value from PME curriculum. <strong>Results:</strong> Four categories emerged from PME graduated alumni: Category <strong>I</strong>, Professional academic performance, Category<strong> II</strong>, International activities attendance, Category <strong>III</strong>, Academic networks, and Category <strong>IV</strong>, Higher satisfaction of international activities.<strong> Conclusions:</strong> It is concluded that self-evaluation shows a graduate’s vision of conditions and networks where PME develops. Masters in Nursing Program fulfills graduates expectancy to create networks, which will contribute to knowledge and recognition of professional practice, as well as on the area’ opportunities opening for better contributions.展开更多
The United States Environmental Protection Agency (EPA) has the authority to regulate the public water systems. The EPA does not have the jurisdiction to regulate private drinking water wells. This leaves approximatel...The United States Environmental Protection Agency (EPA) has the authority to regulate the public water systems. The EPA does not have the jurisdiction to regulate private drinking water wells. This leaves approximately fifteen percent of the nation’s population without any regulation being held in place to protect their source of drinking water. With that fifteen percent of the US population having private wells for drinking water, it makes the number of people whose drinking water is unprotected by regulation at a little over 15 million US households. This concern is even more acute in areas with groundwater that is close to the surface. Delaware residents live in a region with low elevation which is very close to the coast with low elevation and the shallow groundwater makes us concern about contaminated well water even more intense. As one of the Water Resources Program partners, we have offered free Drinking Water Quality Clinics to local well owners over the past 4 years in Delaware State University. Since 2009, over 400 Delaware residents have benefited from these clinics. At each clinic, an information session was offered in the evening, with an opportunity to hear from and speak with a drinking water well expert. Participants were given sample bottles and water testing performed the following day included pH, nitrite, nitrate, sulfate, alkalinity, fluoride, hardness, iron, lead, cadmium, arsenic, Total Coliform, and E. coli. Over half of the samples returned out of range values for pH, while 72 returned results positive for Total Coliform and Escherichia coli bacterium. Data are examined for correlations, and improved understanding of local well owners. These tests shared with local well owners insights into what may be wrong with their water. In addition, any tests that came back outside of the normal range were reported to homeowners in writing. Mailed with the written reports were also information specific to what test results were outside of the limits, and actions to take to correct the exact problem the well owners encountered. The data reported here are examined to discuss the correlations of information, and ways that the Drinking Water Quality Clinics have improved our understanding of local wells and ownerships. In conclusion, regular testing on a yearly basis is the most effective way to ensure that public health is maintained.展开更多
目的系统评价中医外治法治疗子宫腺肌病(AM)的有效性与安全性。方法检索建库至2024年11月中国知网、万方数据库、中国生物医学文献数据库、Pub Med、Web of Science中所有关于中医外治法治疗AM的随机对照试验(RCTs),采用Rev Man 5.4.1...目的系统评价中医外治法治疗子宫腺肌病(AM)的有效性与安全性。方法检索建库至2024年11月中国知网、万方数据库、中国生物医学文献数据库、Pub Med、Web of Science中所有关于中医外治法治疗AM的随机对照试验(RCTs),采用Rev Man 5.4.1软件进行Meta分析。结果纳入文献19篇,总样本量1474例,试验组740例,对照组734例。Meta分析结果显示,与对照组比较,中医外治法可显著提高临床总有效率(OR=3.09,95%CI:1.69~5.67,P=0.0003),改善患者视觉模拟评分法(VAS)评分[均数差(MD)=-1.56,95%CI:-2.47~-0.65,P=0.0008]、痛经程度积分[标准化均数差(SMD)=-0.50,95%CI:-0.94~-0.05,P=0.03]、月经量(SMD=-1.18,95%CI:-1.83~-0.53,P=0.0004)、血清糖类抗原125(CA125)水平(MD=-12.01,95%CI:-15.97~-8.04,P<0.00001)及子宫体积(MD=-17.10,95%CI:-24.49~-9.70,P<0.00001),不良反应发生率(OR=0.18,95%CI:0.09~0.35,P<0.00001)低于对照组。结论中医外治法治疗AM临床疗效显著,不良反应较少。展开更多
Holding a dominant position in the spatial planning system at the city level, a city master plan should be able to guide both long-term strategies and short-term planning implementation, while taking into account both...Holding a dominant position in the spatial planning system at the city level, a city master plan should be able to guide both long-term strategies and short-term planning implementation, while taking into account both resource conservation and urban-rural development and coordinating multi-government power and interests of various stakeholders. In the future, city master planning should keep its advanced nature and must follow the principles of being people-oriented, paying equal attention to both development quality and quantity, promoting diversified development, and containing multiple driving forces for development.展开更多
为减少高层装配式住宅的竖向变形,满足工程的实际使用功能,以山东省山东大学某26层装配整体式混凝土剪力墙住宅项目为研究对象,通过对变形情况进行模拟并对比实际施工情况,分析其变形发展变化的内在原因,包括:地基沉降、混凝土收缩徐变、...为减少高层装配式住宅的竖向变形,满足工程的实际使用功能,以山东省山东大学某26层装配整体式混凝土剪力墙住宅项目为研究对象,通过对变形情况进行模拟并对比实际施工情况,分析其变形发展变化的内在原因,包括:地基沉降、混凝土收缩徐变、预制构件连接工艺缺陷、短期施工荷载过早施加及温度应力等因素。采用建筑信息模型(building information modeling,BIM)+激光扫描实施纠偏技术、施工准备阶段三维可视化交底、施工阶段双重精度检测对比纠偏,结合沉降观测、施工预抛高等辅助措施,使竖向变形量降至10 mm,满足规范要求,并缩短了工期、降低了成本,验证了控制措施的有效性。展开更多
基金Project of State Administration of Traditional Chinese Medicine(GZY-YZS-2019-45)The Horizontal Project of Hunan Medical College(HYH-2021Y-KJ-6-33)+1 种基金Scientific Research Project of Hunan Provincial Department of Education in 2021(21C0223)Natural Science Foundation of Hunan Province in 2022(1524)。
文摘Objective This study aimed to examine and propagate the medication experience and group formula of traditional Chinese medicine(TCM)Master XIONG Jibo in diagnosing and treat-ing arthralgia syndrome(AS)through data mining.Methods Data of outpatient cases of Professor XIONG Jibo were collected from January 1,2014 to December 31,2018,along with cases recorded in A Real Famous Traditional Chinese Medicine Doctor:XIONG Jibo's Clinical Medical Record 1,which was published in December 2019.The five variables collected from the patients’data were TCM diagnostic information,TCM and western medicine diagnoses,syndrome,treatment,and prescription.A database was established for the collected data with Excel.Using the Python environment,a custom-ized modified natural language processing(NLP)model for the diagnosis and treatment of AS by Professor XIONG Jibo was established to preprocess the data and to analyze the word cloud.Frequency analysis,association rule analysis,cluster analysis,and visual analysis of AS cases were performed based on the Traditional Chinese Medicine Inheritance Computing Platform(V3.0)and RStudio(V4.0.3).Results A total of 610 medical records of Professor XIONG Jibo were collected from the case database.A total of 103 medical records were included after data screening criteria,which comprised 187 times(45 kinds)of prescriptions and 1506 times(125 kinds)of Chinese herbs.The main related meridians were the liver,spleen,and kidney meridians.The properties of Chinese herbs used most were mainly warm,flat,and cold,while the flavors of herbs were mainly bitter,pungent,and sweet.The main patterns of AS included the damp heat,phlegm stasis,and neck arthralgia.The most commonly used herbs for AS were Chuanniuxi(Cyathu-lae Radix),Huangbo(Phellodendri Chinensis Cortex),Cangzhu(Atractylodis Rhizoma),Qinjiao(Gentianae Macrophyllae Radix),Gancao(Glycyrrhizae Radix et Rhizoma),Huangqi(Astragali Radix),and Chuanxiong(Chuanxiong Rhizoma).The most common effect of the herbs was“promoting blood circulation and removing blood stasis”,followed by“supple-menting deficiency(Qi supplementing,blood supplementing,and Yang supplementing)”,and“dispelling wind and dampness”.The data were analyzed with the support≥15%and con-fidence=100%,and after de-duplication,five second-order association rules,39 third-order association rules,39 fourth-order association rules,and two fifth-order association rules were identified.The top-ranking association rules of each were“Cangzhu(Atractylodis Rhizoma)→Huangbo(Phellodendri Chinensis Cortex)”“Cangzhu(Atractylodis Rhizoma)+Chuanniuxi(Cyathulae Radix)→Huangbo(Phellodendri Chinensis Cortex)”“Chuanniuxi(Cyathulae Radix)+Danggui(Angelicae Sinensis Radix)+Gancao(Glycyrrhizae Radix et Rhizoma)→Qinjiao(Gentianae Macrophyllae Radix)”and“Chuanniuxi(Cyathulae Radix)+Danggui(Angelicae Sinensis Radix)+Gancao(Glycyrrhizae Radix et Rhizoma)+Huangbo(Phello-dendri Chinensis Cortex)→Qinjiao(Gentianae Macrophyllae Radix)”,respectively.Five clusters were obtained using cluster analysis of the top 30 herbs.The herbs were mainly dry-ing dampness,supplementing Qi,and promoting blood circulation.The main prescriptions of AS were Ermiao San(二妙散),Gegen Jianghuang San(葛根姜黄散),and Huangqi Chongteng Yin(黄芪虫藤饮).The herbs of core prescription included Cangzhu(Atractylodis Rhizoma),Chuanniuxi(Cyathulae Radix),Gancao(Glycyrrhizae Radix et Rhizoma),Huangbo(Phellodendri Chinensis Cortex),Mugua(Chaenomelis Fructus),Qinjiao(Gentianae Macro-phyllae Radix),Danggui(Angelicae Sinensis Radix),and Yiyiren(Coicis Semen).Conclusion Clearing heat and dampness,relieving collaterals and pain,and invigorating Qi and blood are the most commonly used therapies for the treatment of AS by Professor XIONG Jibo.Additionally,customized NLP model could improve the efficiency of data mining in TCM.
文摘<strong>Background:</strong> To ensure quality and relevance of Postgraduate Programs are a commitment of the National Quality Postgraduate Programs (PNPC), and those from UNAM. Then, the self-evaluation of the Masters in Nursing Program (PME) is necessary for it to be part of the PNPC. This study focuses on self-evaluation of implementation mechanisms to assure effective communication and collaboration with and among graduated alumni. <strong>Methods:</strong> The research was qualitative, exploratory and descriptive. An informed consent was signed by four informants, graduated from the seventeenth generation of PME. Data collection from a focal group and descriptive data analysis by atlas.ti from guidance questions that were contrasted with the scale value from PME curriculum. <strong>Results:</strong> Four categories emerged from PME graduated alumni: Category <strong>I</strong>, Professional academic performance, Category<strong> II</strong>, International activities attendance, Category <strong>III</strong>, Academic networks, and Category <strong>IV</strong>, Higher satisfaction of international activities.<strong> Conclusions:</strong> It is concluded that self-evaluation shows a graduate’s vision of conditions and networks where PME develops. Masters in Nursing Program fulfills graduates expectancy to create networks, which will contribute to knowledge and recognition of professional practice, as well as on the area’ opportunities opening for better contributions.
文摘The United States Environmental Protection Agency (EPA) has the authority to regulate the public water systems. The EPA does not have the jurisdiction to regulate private drinking water wells. This leaves approximately fifteen percent of the nation’s population without any regulation being held in place to protect their source of drinking water. With that fifteen percent of the US population having private wells for drinking water, it makes the number of people whose drinking water is unprotected by regulation at a little over 15 million US households. This concern is even more acute in areas with groundwater that is close to the surface. Delaware residents live in a region with low elevation which is very close to the coast with low elevation and the shallow groundwater makes us concern about contaminated well water even more intense. As one of the Water Resources Program partners, we have offered free Drinking Water Quality Clinics to local well owners over the past 4 years in Delaware State University. Since 2009, over 400 Delaware residents have benefited from these clinics. At each clinic, an information session was offered in the evening, with an opportunity to hear from and speak with a drinking water well expert. Participants were given sample bottles and water testing performed the following day included pH, nitrite, nitrate, sulfate, alkalinity, fluoride, hardness, iron, lead, cadmium, arsenic, Total Coliform, and E. coli. Over half of the samples returned out of range values for pH, while 72 returned results positive for Total Coliform and Escherichia coli bacterium. Data are examined for correlations, and improved understanding of local well owners. These tests shared with local well owners insights into what may be wrong with their water. In addition, any tests that came back outside of the normal range were reported to homeowners in writing. Mailed with the written reports were also information specific to what test results were outside of the limits, and actions to take to correct the exact problem the well owners encountered. The data reported here are examined to discuss the correlations of information, and ways that the Drinking Water Quality Clinics have improved our understanding of local wells and ownerships. In conclusion, regular testing on a yearly basis is the most effective way to ensure that public health is maintained.
文摘目的系统评价中医外治法治疗子宫腺肌病(AM)的有效性与安全性。方法检索建库至2024年11月中国知网、万方数据库、中国生物医学文献数据库、Pub Med、Web of Science中所有关于中医外治法治疗AM的随机对照试验(RCTs),采用Rev Man 5.4.1软件进行Meta分析。结果纳入文献19篇,总样本量1474例,试验组740例,对照组734例。Meta分析结果显示,与对照组比较,中医外治法可显著提高临床总有效率(OR=3.09,95%CI:1.69~5.67,P=0.0003),改善患者视觉模拟评分法(VAS)评分[均数差(MD)=-1.56,95%CI:-2.47~-0.65,P=0.0008]、痛经程度积分[标准化均数差(SMD)=-0.50,95%CI:-0.94~-0.05,P=0.03]、月经量(SMD=-1.18,95%CI:-1.83~-0.53,P=0.0004)、血清糖类抗原125(CA125)水平(MD=-12.01,95%CI:-15.97~-8.04,P<0.00001)及子宫体积(MD=-17.10,95%CI:-24.49~-9.70,P<0.00001),不良反应发生率(OR=0.18,95%CI:0.09~0.35,P<0.00001)低于对照组。结论中医外治法治疗AM临床疗效显著,不良反应较少。
文摘Holding a dominant position in the spatial planning system at the city level, a city master plan should be able to guide both long-term strategies and short-term planning implementation, while taking into account both resource conservation and urban-rural development and coordinating multi-government power and interests of various stakeholders. In the future, city master planning should keep its advanced nature and must follow the principles of being people-oriented, paying equal attention to both development quality and quantity, promoting diversified development, and containing multiple driving forces for development.
文摘为减少高层装配式住宅的竖向变形,满足工程的实际使用功能,以山东省山东大学某26层装配整体式混凝土剪力墙住宅项目为研究对象,通过对变形情况进行模拟并对比实际施工情况,分析其变形发展变化的内在原因,包括:地基沉降、混凝土收缩徐变、预制构件连接工艺缺陷、短期施工荷载过早施加及温度应力等因素。采用建筑信息模型(building information modeling,BIM)+激光扫描实施纠偏技术、施工准备阶段三维可视化交底、施工阶段双重精度检测对比纠偏,结合沉降观测、施工预抛高等辅助措施,使竖向变形量降至10 mm,满足规范要求,并缩短了工期、降低了成本,验证了控制措施的有效性。
