In this paper, the Lie symmetry algebra of the coupled Kadomtsev-Petviashvili （cKP） equation is obtained by the classical Lie group method and this algebra is shown to have a Kac-Moody-Virasoro loop algebra structur...In this paper, the Lie symmetry algebra of the coupled Kadomtsev-Petviashvili （cKP） equation is obtained by the classical Lie group method and this algebra is shown to have a Kac-Moody-Virasoro loop algebra structure. Then the general symmetry groups of the cKP equation is also obtained by the symmetry group direct method which is proposed by Lou et alo From the general symmetry groups, the Lie symmetry group can be recovered and a group of discrete transformations can be derived simultaneously. Lastly, from a known simple solution of the cKP equation, we can easily obtain two new solutions by the general symmetry groups.展开更多
By Lie symmetry method, the Lie point symmetries and its Kac-Moody-Virasoro (KMV) symmetry algebra of (2+1)-dimensional dispersive long-wave equation (DLWE) are obtained, and the finite transformation of DLWE is given...By Lie symmetry method, the Lie point symmetries and its Kac-Moody-Virasoro (KMV) symmetry algebra of (2+1)-dimensional dispersive long-wave equation (DLWE) are obtained, and the finite transformation of DLWE is given by symmetry group direct method, which can recover Lie point symmetries. Then KMV symmetry algebra of DLWE with arbitrary order invariant is also obtained. On basis of this algebra the group invariant solutions and similarity reductions are also derived.展开更多
The presence of inflammation in dry eye disease(DED)results in increased patient symptomatology,ocular surface damage and worsening tear dysfunction.It also affects the health of meibomian glands and their secretions ...The presence of inflammation in dry eye disease(DED)results in increased patient symptomatology,ocular surface damage and worsening tear dysfunction.It also affects the health of meibomian glands and their secretions which further aggravates ocular surface disease.This article reviews current knowledge regarding ocular surface inflammation in DED and explores the relationships between the vicious cycles of DED,inflammation and meibomian gland dysfunction(MGD).The clinical evaluation of eyes with such changes,markers that identify the presence of inflammation on the ocular surface and current treatment options are discussed.展开更多
In this paper, the extended symmetry of generalized variable-coeFficient Kadomtsev-Petviashvili （vcKP） equation is investigated by the extended symmetry group method with symbolic computation. Then on the basis of t...In this paper, the extended symmetry of generalized variable-coeFficient Kadomtsev-Petviashvili （vcKP） equation is investigated by the extended symmetry group method with symbolic computation. Then on the basis of the extended symmetry, we can establish relation among some different kinds of vcKP equations. Thus the exact solutions of these veKP equations can be constructed via the simple veKP equations or constant-coefficient KP equations.展开更多
The present paper reports 11 cases of light chain disease (LCD) sequently found in several citles over Fujian province, Immunological classification of this group of LCD ww as follows: six of me cases belonged to type...The present paper reports 11 cases of light chain disease (LCD) sequently found in several citles over Fujian province, Immunological classification of this group of LCD ww as follows: six of me cases belonged to type λ, four of them were type κ, and another one was a double LCD. We found that LCD was common in Fujlan only next to multiple myeloma (MM) of IgG class and accounted for 20% of the total 55 MM cases found in recent yean.It to well known that In matt patients of LCD M protein or Bence Jones proteinemia (BJPemia) to not detectable by conventional electro-phoresis. Our studies show that by making serum protein along with urinary BJP electrophoresis on the same one gel plate the sltuation can be greatly Improved It not only favour* the recognition of smail and faint band or bands of free light chain in serum, but also provides a repid and sensitive way, i. e. , immunofixation, to directly detect urinary light chain on the gel plate Immediately after electrophresis has been run.展开更多
The density of dendritic cells (DC) and macro-phages (Mφ) in tissue specimens of gastric carcinoma (GC n=65) was investigated by ABC im-munohistochemical method using anti-S100 protein and anti-lysozyme antibodies, a...The density of dendritic cells (DC) and macro-phages (Mφ) in tissue specimens of gastric carcinoma (GC n=65) was investigated by ABC im-munohistochemical method using anti-S100 protein and anti-lysozyme antibodies, and was compared with that in gastric ulcer (GU n=19), chronic atrophic gastritis (CAG n=28) and normal gastric mucosa (NGM n=15). The mean density if DC (cells/mm2) in GC (15.0 was significantly higher than that in NGM (3.8) and GU (8.3), but was remarkably lower when compared to that in CAG (29.5) (P<0.01). Statistically significant difference in the population density of DC was observed between well- and poorly-differentiated GC (P<0.01). With their unique dendritic processes, DC were mainly concentrated within dense lymphoid infiltrates or in the T-area of reactive lymphoid follicles and were interspersed among the tumor cells. In contrast, Mφ were present around the necrotic foci and were rarely seen within the non-necrotic neoplastic tissues. These data suggest that DC, which differ in morphology, distribution, number and function form Mφ may be more directly involved in the host immune reaction against tumor by acting as antigen presenting cells.展开更多
Thin potato crisps (2mm) were fried at 170℃, 180℃ and 190℃ for varioustimes from 10s to 180s inclusive. It was found that definite oil uptake, moisture loss trends existduring the frying process. No significant dif...Thin potato crisps (2mm) were fried at 170℃, 180℃ and 190℃ for varioustimes from 10s to 180s inclusive. It was found that definite oil uptake, moisture loss trends existduring the frying process. No significant difference in the oil uptake or moisture loss ratesbetween flat-cut and ridge-cut crisps exists. Also found in this study was that an increased oiltemperature promoted higher moisture loss rates. In turn, the higher moisture loss rates contributedto a higher oil uptake rate. It was found, based on the volumetric plots of oil content υs. watercontent, that the oil uptake rate was proportional to the moisture loss rate. As a result, it hasbeen shown that there is a possibility of having a characteristic curve of oil uptake againstmoisture content.展开更多
Background:Inflammatory diseases are among the leading causes of health issues that considerably influence health care costs.Despite the notable advancements in medical treatment that have been made in recent years,na...Background:Inflammatory diseases are among the leading causes of health issues that considerably influence health care costs.Despite the notable advancements in medical treatment that have been made in recent years,natural products with biological activity still play essential roles in a variety of anti-inflammatory conditions.The study and identification of novel treatments for the adverse effects of available synthetic anti-inflammatory agents warrant further attention.Objective:This study focused on the emerging therapeutic potential of terpenoid products as anti-inflammatory agents.Methods:The literature reveals that secondary metabolites obtained from medicinal plants,viz.terpenes and terpenoids and their nanoformulations,are effective for the treatment of inflammation in humans.Established terpenes are a broad class of secondary metabolites that are rich in monoterpenes,diterpenes,triterpenes,tetraterpenes,ceramides,and sesquiterpenes and have various therapeutic applications,such as antitumor,antibacterial,antimicrobial,analgesic and anti-inflammatory activities.Numerous studies have shown that terpenes can decrease inflammation-associated symptoms by reducing the release of proinflammatory cytokines,including nuclear transcription factor-kappa B,interleukins,tumor necrosis factor-alpha,and other inflammatory mediators.Conclusion:This review describes the latest knowledge of the different terpenoid-derived natural and synthetic compounds that have been isolated from plant sources in recent years and their anti-inflammatory potential and therapeutic mechanism of action.Furthermore,this study focused on terpenoid-based nanoformulations with enhanced bioavailability and improved therapeutic efficacy as anti-inflammatory agents.展开更多
Background:Glioblastoma multiforme(GBM)is recognized as the most lethal and most highly invasive tumor.The high likelihood of treatment failure arises fromthe presence of the blood-brain barrier(BBB)and stemcells arou...Background:Glioblastoma multiforme(GBM)is recognized as the most lethal and most highly invasive tumor.The high likelihood of treatment failure arises fromthe presence of the blood-brain barrier(BBB)and stemcells around GBM,which avert the entry of chemotherapeutic drugs into the tumormass.Objective:Recently,several researchers have designed novel nanocarrier systems like liposomes,dendrimers,metallic nanoparticles,nanodiamonds,and nanorobot approaches,allowing drugs to infiltrate the BBB more efficiently,opening up innovative avenues to prevail over therapy problems and radiation therapy.Methods:Relevant literature for this manuscript has been collected from a comprehensive and systematic search of databases,for example,PubMed,Science Direct,Google Scholar,and others,using specific keyword combinations,including“glioblastoma,”“brain tumor,”“nanocarriers,”and several others.Conclusion:This review also provides deep insights into recent advancements in nanocarrier-based formulations and technologies for GBM management.Elucidation of various scientific advances in conjunction with encouraging findings concerning the future perspectives and challenges of nanocarriers for effective brain tumor management has also been discussed.展开更多
基金Project supported by the National Natural Science Foundation of China (Grant Nos 10747141 and 10735030)National Basic Research Program of China (Grant No 2007CB814800)+2 种基金Natural Science Foundations of Zhejiang Province of China (Grant No605408)Ningbo Natural Science Foundation (Grant Nos 2007A610049 and 2008A610017)K. C.Wong Magna Fund in Ningbo University
文摘In this paper, the Lie symmetry algebra of the coupled Kadomtsev-Petviashvili （cKP） equation is obtained by the classical Lie group method and this algebra is shown to have a Kac-Moody-Virasoro loop algebra structure. Then the general symmetry groups of the cKP equation is also obtained by the symmetry group direct method which is proposed by Lou et alo From the general symmetry groups, the Lie symmetry group can be recovered and a group of discrete transformations can be derived simultaneously. Lastly, from a known simple solution of the cKP equation, we can easily obtain two new solutions by the general symmetry groups.
基金Supported by the Natural Science Foundation of China under Grant No. 10735030Ningbo Natural Science Foundation under Grant No. 2008A610017+3 种基金National Basic Research Program of China (973 Program 2007CB814800)Shanghai Leading Academic Discipline Project under Grant No. B412Program for Changjiang Scholars and Innovative Research Team in University (IRT0734)K.C. Wong Magna Fund in Ningbo University
文摘By Lie symmetry method, the Lie point symmetries and its Kac-Moody-Virasoro (KMV) symmetry algebra of (2+1)-dimensional dispersive long-wave equation (DLWE) are obtained, and the finite transformation of DLWE is given by symmetry group direct method, which can recover Lie point symmetries. Then KMV symmetry algebra of DLWE with arbitrary order invariant is also obtained. On basis of this algebra the group invariant solutions and similarity reductions are also derived.
文摘The presence of inflammation in dry eye disease(DED)results in increased patient symptomatology,ocular surface damage and worsening tear dysfunction.It also affects the health of meibomian glands and their secretions which further aggravates ocular surface disease.This article reviews current knowledge regarding ocular surface inflammation in DED and explores the relationships between the vicious cycles of DED,inflammation and meibomian gland dysfunction(MGD).The clinical evaluation of eyes with such changes,markers that identify the presence of inflammation on the ocular surface and current treatment options are discussed.
基金Supported by the National Natural Science Foundation of China under Grant No. 0735030Zhejiang Provincial Natural Science Foundations of China under Grant No. Y6090592+1 种基金National Basic Research Program of China (973 Program 2007CB814800)Ningbo Natural Science Foundation under Grant No. 2008A610017 and K.C. Wong Magna Fund in Ningbo University
文摘In this paper, the extended symmetry of generalized variable-coeFficient Kadomtsev-Petviashvili （vcKP） equation is investigated by the extended symmetry group method with symbolic computation. Then on the basis of the extended symmetry, we can establish relation among some different kinds of vcKP equations. Thus the exact solutions of these veKP equations can be constructed via the simple veKP equations or constant-coefficient KP equations.
文摘The present paper reports 11 cases of light chain disease (LCD) sequently found in several citles over Fujian province, Immunological classification of this group of LCD ww as follows: six of me cases belonged to type λ, four of them were type κ, and another one was a double LCD. We found that LCD was common in Fujlan only next to multiple myeloma (MM) of IgG class and accounted for 20% of the total 55 MM cases found in recent yean.It to well known that In matt patients of LCD M protein or Bence Jones proteinemia (BJPemia) to not detectable by conventional electro-phoresis. Our studies show that by making serum protein along with urinary BJP electrophoresis on the same one gel plate the sltuation can be greatly Improved It not only favour* the recognition of smail and faint band or bands of free light chain in serum, but also provides a repid and sensitive way, i. e. , immunofixation, to directly detect urinary light chain on the gel plate Immediately after electrophresis has been run.
文摘The density of dendritic cells (DC) and macro-phages (Mφ) in tissue specimens of gastric carcinoma (GC n=65) was investigated by ABC im-munohistochemical method using anti-S100 protein and anti-lysozyme antibodies, and was compared with that in gastric ulcer (GU n=19), chronic atrophic gastritis (CAG n=28) and normal gastric mucosa (NGM n=15). The mean density if DC (cells/mm2) in GC (15.0 was significantly higher than that in NGM (3.8) and GU (8.3), but was remarkably lower when compared to that in CAG (29.5) (P<0.01). Statistically significant difference in the population density of DC was observed between well- and poorly-differentiated GC (P<0.01). With their unique dendritic processes, DC were mainly concentrated within dense lymphoid infiltrates or in the T-area of reactive lymphoid follicles and were interspersed among the tumor cells. In contrast, Mφ were present around the necrotic foci and were rarely seen within the non-necrotic neoplastic tissues. These data suggest that DC, which differ in morphology, distribution, number and function form Mφ may be more directly involved in the host immune reaction against tumor by acting as antigen presenting cells.
文摘Thin potato crisps (2mm) were fried at 170℃, 180℃ and 190℃ for varioustimes from 10s to 180s inclusive. It was found that definite oil uptake, moisture loss trends existduring the frying process. No significant difference in the oil uptake or moisture loss ratesbetween flat-cut and ridge-cut crisps exists. Also found in this study was that an increased oiltemperature promoted higher moisture loss rates. In turn, the higher moisture loss rates contributedto a higher oil uptake rate. It was found, based on the volumetric plots of oil content υs. watercontent, that the oil uptake rate was proportional to the moisture loss rate. As a result, it hasbeen shown that there is a possibility of having a characteristic curve of oil uptake againstmoisture content.
文摘Background:Inflammatory diseases are among the leading causes of health issues that considerably influence health care costs.Despite the notable advancements in medical treatment that have been made in recent years,natural products with biological activity still play essential roles in a variety of anti-inflammatory conditions.The study and identification of novel treatments for the adverse effects of available synthetic anti-inflammatory agents warrant further attention.Objective:This study focused on the emerging therapeutic potential of terpenoid products as anti-inflammatory agents.Methods:The literature reveals that secondary metabolites obtained from medicinal plants,viz.terpenes and terpenoids and their nanoformulations,are effective for the treatment of inflammation in humans.Established terpenes are a broad class of secondary metabolites that are rich in monoterpenes,diterpenes,triterpenes,tetraterpenes,ceramides,and sesquiterpenes and have various therapeutic applications,such as antitumor,antibacterial,antimicrobial,analgesic and anti-inflammatory activities.Numerous studies have shown that terpenes can decrease inflammation-associated symptoms by reducing the release of proinflammatory cytokines,including nuclear transcription factor-kappa B,interleukins,tumor necrosis factor-alpha,and other inflammatory mediators.Conclusion:This review describes the latest knowledge of the different terpenoid-derived natural and synthetic compounds that have been isolated from plant sources in recent years and their anti-inflammatory potential and therapeutic mechanism of action.Furthermore,this study focused on terpenoid-based nanoformulations with enhanced bioavailability and improved therapeutic efficacy as anti-inflammatory agents.
文摘Background:Glioblastoma multiforme(GBM)is recognized as the most lethal and most highly invasive tumor.The high likelihood of treatment failure arises fromthe presence of the blood-brain barrier(BBB)and stemcells around GBM,which avert the entry of chemotherapeutic drugs into the tumormass.Objective:Recently,several researchers have designed novel nanocarrier systems like liposomes,dendrimers,metallic nanoparticles,nanodiamonds,and nanorobot approaches,allowing drugs to infiltrate the BBB more efficiently,opening up innovative avenues to prevail over therapy problems and radiation therapy.Methods:Relevant literature for this manuscript has been collected from a comprehensive and systematic search of databases,for example,PubMed,Science Direct,Google Scholar,and others,using specific keyword combinations,including“glioblastoma,”“brain tumor,”“nanocarriers,”and several others.Conclusion:This review also provides deep insights into recent advancements in nanocarrier-based formulations and technologies for GBM management.Elucidation of various scientific advances in conjunction with encouraging findings concerning the future perspectives and challenges of nanocarriers for effective brain tumor management has also been discussed.
