After more than 20 years of development, great changes have taken place in Yuzhong Campus of Lanzhou University. Standing at the new starting point of the construction of "double first-class" universities, t...After more than 20 years of development, great changes have taken place in Yuzhong Campus of Lanzhou University. Standing at the new starting point of the construction of "double first-class" universities, the future development of campus is very important. Using the high-resolution images taken by Landsat and unmanned aerial vehicles. Based on remote sensing and GIS analysis technology, this paper analyzes the land use change, road system, plot ratio, etc. of Yuzhong Campus in the past 20 years, summarizes the development law of the campus over the years, and based on this, provides suggestions for future development, which has certain practical significance for the future construction of Yuzhong Campus and ecological innovation city.展开更多
Urban open spaces(UOS)play a crucial role in enhancing city livability and resident well-being,yet there remains a gap in utilizing social media to analyze changes in UOS utilization across different COVID(Corona Viru...Urban open spaces(UOS)play a crucial role in enhancing city livability and resident well-being,yet there remains a gap in utilizing social media to analyze changes in UOS utilization across different COVID(Corona Virus Disease)-19 phases.Our research applied Sina Weibo data to scrutinize UOS engagement across pre-pandemic(2019),pandemic(2021),and post-pandemic(2023)periods in Lanzhou City,China,revealing evolving spatiotemporal patterns and highlighting the pandemic's impact on UOS usage.Initially,scenic mountains and urban parks dominated visitor preferences in 2019.However,during the pandemic,there was a trend towards destinations that combined elements of tourism,business,entertainment,and culture,reflecting a growing appetite for diverse experiences.Despite this shift,the post-pandemic period did not see a complete return to pre-pandemic travel patterns,with a noticeable decline in visits to traditional green open spaces during lockdowns.We identified key attractions in main urban areas,highlighting geographical variations in tourism and Cultural Ecosystem Services(CES)distribution that warrant further attention.The post-pandemic landscape reveals a resurging interest in green-blue spaces and nature-focused tourism,highlighting a continued preference for cultural and natural experiences,and emphasizing the need to harmonize development with the preservation of natural and cultural heritage.This study introduces the use of social media data across pandemic phases to guide UOS management,offering insights for creating resilient,multifunctional urban spaces that address public needs and enhance community well-being.展开更多
A restoration concept has been developed based on the Baiyun Taoist Temple Map found in the Continuation of the Gaolan County Annals.This study systematically analyzes the architectural features of Baiyun Taoist Templ...A restoration concept has been developed based on the Baiyun Taoist Temple Map found in the Continuation of the Gaolan County Annals.This study systematically analyzes the architectural features of Baiyun Taoist Temple in Lanzhou during the Daoguang period of the Qing Dynasty from three perspectives:overall layout,spatial design,and garden artistic conception.The analysis offers a representative case for understanding the spatial organization principles and cultural connotation of Taoist architecture in the Lanzhou region during the Qing Dynasty.展开更多
Soundscape has been attracting more attention as a key landscape component,its effect on environmental perception relies not only on the physical attributes of sounds,but also the co-influence and interaction of sound...Soundscape has been attracting more attention as a key landscape component,its effect on environmental perception relies not only on the physical attributes of sounds,but also the co-influence and interaction of sound sources and surroundings.To systematically identify the objective soundscape characteristics in the wetland park and the influence factors,this paper applied sound walk method to investigate the sound source types,sound pressure level(SPL),and objects and subjects’soundscape perception.The results showed that artificial sounds accounted for the most of soundscapes in the park(60%),natural sounds accounted for 25%,life sounds about 15%.Among the natural sounds,bird chirping and frog croaking were the favorite of users;the mean equivalent continuous A sound level of each measure point in the park was 50.2 dB,complying with the national standard limit value.Optimization of the sound environment in the wetland park should comprehensively consider the landscape layout,current characteristics and users’requirements,relevant designs and management strategies are of great practical significance for improving the quality of soundscape and the comfort degree of overall environment.展开更多
The Yellow River(YR),China’s second-longest river,remains understudied regarding its greenhouse gases(GHGs)emissions,particularly the impacts of urban drainage ditches and wastewater treatment facilities on regional ...The Yellow River(YR),China’s second-longest river,remains understudied regarding its greenhouse gases(GHGs)emissions,particularly the impacts of urban drainage ditches and wastewater treatment facilities on regional GHGs dynamics.This study investigated methane(CH_(4))and carbon dioxide(CO_(2))concentrations,fluxes and stable carbon isotopes(δ^(13)C-CH_(4)and δ^(13)C-CO_(2))across six main stream,three ditches,and one wastewater treatment site along the upper Lanzhou section of the YR,spanning from the urban entrance(36.176°N,103.449°E)to the exit of Lanzhou city(36.056°N,104.020°E).Measured CH_(4)diffusion fluxes in mainstem sites ranged from 0.01 to 2.58 mmol·m^(−2)·d^(−1)(mean:0.36 mmol·m^(−2)·d^(−1)),while ebullitive fluxes(gas bubbles)ranged from 0.01 to 18.89 mmol·m^(−2)·d^(−1)(mean:0.90 mmol·m^(−2)·d^(−1)).CO_(2)diffusion fluxes varied between 9.16–92.80 mmol·m^(−2)·d^(−1)(averaged:39.11 mmol·m^(−2)·d^(−1))at these locations.Ebullition(bubble)fluxes accounted for 53.1%±22.4%(range:9.0%to 98.4%)to total CH_(4)emissions(diffusion plus ebullition),with peak fluxes occurring during summer,indicating its significance as a CH_(4)transport mechanism.Notably,both diffusion CH_(4)and CO_(2)fluxes and ebullitive CH_(4)rates at ditch sites substantially exceeded those in mainstream reaches.The lowest CH_(4)and highest CO_(2)concentrations were observed at a wastewater treatment site,likely resulting from the removal of high organic loads.Acetoclastic methanogenesis—the process converting acetate-derived methyl groups to CH_(4)—was identified as the dominant production pathway in both mainstream and ditch environments.CH_(4)and CO_(2)flux magnitudes in the upper YR(Lanzhou section)were comparable to those observed in subtropical Yangtze River tributaries.These results demonstrate that anthropogenic influences significantly enhance CO_(2)/CH_(4)emissions,and the lateral exports of dissolved carbon(DIC and DOC)in the main stream site was quantified.,which cannot be overlooked.The findings emphasize the critical need to account for pronounced spatiotemporal variations in arid-region GHG fluxes to improve basin-scale estimates for the YR.展开更多
Three zinc(Ⅱ),nickel(Ⅱ),and cadmium(Ⅱ)complexes,namely[Zn(μ-Htpta)(py)_(2)]n(1),[Ni(H_(2)biim)2(H_(2)O)2][Ni(tpta)(H_(2)biim)2(H_(2)O)]2·3H_(2)O(2),and[Cd_(3)(μ4-tpta)2(μ-dpe)_(3)]_(n)(3),have been construc...Three zinc(Ⅱ),nickel(Ⅱ),and cadmium(Ⅱ)complexes,namely[Zn(μ-Htpta)(py)_(2)]n(1),[Ni(H_(2)biim)2(H_(2)O)2][Ni(tpta)(H_(2)biim)2(H_(2)O)]2·3H_(2)O(2),and[Cd_(3)(μ4-tpta)2(μ-dpe)_(3)]_(n)(3),have been constructed hydrothermally at 160℃ using H_(3)tpta([1,1':3',1″-terphenyl]-4,4',5'-tricarboxylic acid),py(pyridine),H_(2)biim(2,2'-biimidazole),dpe(1,2-di(4-pyridyl)ethylene),and zinc,nickel and cadmium chlorides,resulting in the formation of stable crystalline solids which were subsequently analyzed using infrared spectroscopy,element analysis,thermogravimetric analysis,as well as structural analyses conducted via single-crystal X-ray diffraction.The findings from these single-crystal Xray diffraction studies indicate that complexes 1-3 form crystals within the monoclinic system P2_(1)/c space group(1)or triclinic system P1 space group(2 and 3),and possess 1D,0D,and 3D structures,respectively.Complex 1 demonstrated substantial catalytic efficiency and excellent reusability as a heterogeneous catalyst in the reaction of Knoevenagel condensation under ambient temperature conditions.In addition,complex 1 also showcased notable anti-wear performance when used in polyalphaolefin synthetic lubricants.CCDC:2449810,1;2449811,2;2449812,3.展开更多
Spinal cord ischemia-reperfusion injury,a severe form of spinal cord damage,can lead to sensory and motor dysfunction.This injury often occurs after traumatic events,spinal cord surgeries,or thoracoabdominal aortic su...Spinal cord ischemia-reperfusion injury,a severe form of spinal cord damage,can lead to sensory and motor dysfunction.This injury often occurs after traumatic events,spinal cord surgeries,or thoracoabdominal aortic surgeries.The unpredictable nature of this condition,combined with limited treatment options,poses a significant burden on patients,their families,and society.Spinal cord ischemia-reperfusion injury leads to reduced neuronal regenerative capacity and complex pathological processes.In contrast,mitophagy is crucial for degrading damaged mitochondria,thereby supporting neuronal metabolism and energy supply.However,while moderate mitophagy can be beneficial in the context of spinal cord ischemia-reperfusion injury,excessive mitophagy may be detrimental.Therefore,this review aims to investigate the potential mechanisms and regulators of mitophagy involved in the pathological processes of spinal cord ischemia-reperfusion injury.The goal is to provide a comprehensive understanding of recent advancements in mitophagy related to spinal cord ischemia-reperfusion injury and clarify its potential clinical applications.展开更多
In the context of modern software development characterized by increasing complexity and compressed development cycles,traditional static vulnerability detection methods face prominent challenges including high false ...In the context of modern software development characterized by increasing complexity and compressed development cycles,traditional static vulnerability detection methods face prominent challenges including high false positive rates and missed detections of complex logic due to their over-reliance on rule templates.This paper proposes a Syntax-Aware Hierarchical Attention Network(SAHAN)model,which achieves high-precision vulnerability detection through grammar-rule-driven multi-granularity code slicing and hierarchical semantic fusion mechanisms.The SAHAN model first generates Syntax Independent Units(SIUs),which slices the code based on Abstract Syntax Tree(AST)and predefined grammar rules,retaining vulnerability-sensitive contexts.Following this,through a hierarchical attention mechanism,the local syntax-aware layer encodes fine-grained patterns within SIUs,while the global semantic correlation layer captures vulnerability chains across SIUs,achieving synergistic modeling of syntax and semantics.Experiments show that on benchmark datasets like QEMU,SAHAN significantly improves detection performance by 4.8%to 13.1%on average compared to baseline models such as Devign and VulDeePecker.展开更多
Ambient fine particulate matter(PM_(2.5))pollution causes the largest environmental health risk globally,yet ex-posure levels and the resulting health risks vary across countries with different income levels.Global we...Ambient fine particulate matter(PM_(2.5))pollution causes the largest environmental health risk globally,yet ex-posure levels and the resulting health risks vary across countries with different income levels.Global wealth inequality has intensified in recent years,yet the relationship between wealth inequality and health risks related to PM_(2.5) pollution remains poorly understood.In this study,we evaluated the global mortality and health cost at-tributable to PM_(2.5) exposure from 2017 to 2021,and analyzed the relationship between wealth inequality,PM_(2.5) pollution,and the associated health risks across regions with varying economic levels.We found a consistent decline in mortalities and health costs attributable to PM_(2.5) exposure from 2017 to 2020,followed by a rebound after 2020,driven primarily by the resurgence of PM_(2.5) concentrations and a deceleration in the reduction of baseline mortality rates.We also found that the average PM_(2.5) concentration and associated risks decrease as domestic wealth inequality decreases and national income level increases.However,regions with extremely high levels of wealth inequality consistently show lower national average PM_(2.5) concentrations and health risks.These findings highlight the need to consider healthcare security during emergencies,as well as policy fairness across economic regions,in the formulation of global PM_(2.5) pollution control measures to promote sustainable,more equitable economic growth and coordinated air pollution management.展开更多
This study investigates the impact of vegetation-climate feedback on the global land monsoon system during the Last Interglacial(LIG,127000 years BP)and the mid-Holocene(MH,6000 years BP)using the earth system model E...This study investigates the impact of vegetation-climate feedback on the global land monsoon system during the Last Interglacial(LIG,127000 years BP)and the mid-Holocene(MH,6000 years BP)using the earth system model EC-Earth3.Our findings indicate that vegetation changes significantly influence the global monsoon area and precipitation patterns,especially in the North African and Indian monsoon regions.The North African monsoon region experienced the most substantial increase in vegetation during both the LIG and MH,resulting in significant increases in monsoonal precipitation by 9.8%and 6.0%,respectively.The vegetation feedback also intensified the Saharan Heat Low,strengthened monsoonal flows,and enhanced precipitation over the North African monsoon region.In contrast,the Indian monsoon region exhibited divergent responses to vegetation changes.During the LIG,precipitation in the Indian monsoon region decreased by 2.2%,while it increased by 1.6%during the MH.These differences highlight the complex and region-specific impacts of vegetation feedback on monsoon systems.Overall,this study demonstrates that vegetation feedback exerts distinct influences on the global monsoon during the MH and LIG.These findings highlight the importance of considering vegetation-climate feedback in understanding past monsoon variability and in predicting future climate change impacts on monsoon systems.展开更多
Aeolian deposits across the Yarlung Zangbo River Basin on the southern Tibetan Plateau record the landscape and atmospheric evolution of Earth's Third Pole.The complex mountain-basin system exhibits nonlinear resp...Aeolian deposits across the Yarlung Zangbo River Basin on the southern Tibetan Plateau record the landscape and atmospheric evolution of Earth's Third Pole.The complex mountain-basin system exhibits nonlinear responses to climate forcing,complicating the interpretation of its high-altitude environmental dynamics.Investigating the magnetic enhancement mechanism of aeolian deposits offers an opportunity to decipher climate signals.Our analysis of three aeolian sections from the basin indicates that magnetic minerals are predominantly low-coercivity ferrimagnetic minerals,and grain sizes fine from upper to lower reaches due to climate shifts from arid to humid.Magnetic enhancement in the upper reaches primarily originates from dust input,while dust input and pedogenesis contribute variably over time in the middle and lower reaches.Similar complex patterns occur in the Ili basin,a mountain-basin system in northwestern China.They differ from the Chinese Loess Plateau,where long-distance-transported dust is well-mixed and the pedogenic enhancement model is applied,and desert peripheries where short-distance dust is transported and the dust input model is applied.We summarize the magnetic enhancement mechanisms in various settings and offer a new framework for applying magnetic techniques in paleoclimate reconstruction within global mountain-basin systems,which highlights the need for caution in interpreting their magnetic susceptibility records.展开更多
AIM:To identify key genes and inflammatory signaling pathways involved in the anti-inflammatory effects of Hedysarum polybotrys polysaccharide(HPS)in a rat model of endotoxin-induced uveitis(EIU).METHODS:EIU was induc...AIM:To identify key genes and inflammatory signaling pathways involved in the anti-inflammatory effects of Hedysarum polybotrys polysaccharide(HPS)in a rat model of endotoxin-induced uveitis(EIU).METHODS:EIU was induced in Wistar rats through subcutaneous injection of lipopolysaccharide(LPS,200μg)and the rats were then randomly assigned to EIU group(n=5)and the HPS intervention group(n=5).HPS(400 mg/kg,intraperitoneally)or its carrier was administered 24h and 1h prior to EIU induction.Eyes were examined and enucleated 24h post-induction,and total RNA was extracted from the iris-ciliary body.Gene expression microarrays were used to identify differentially expressed genes(DEGs),followed by bioinformatics analyses,including gene ontology(GO)and pathway analysis.Key findings were not experimentally validated at the mRNA or protein level.RESULTS:A total of 322 DEGs were identified,comprising 254 mRNA and 68 lncRNA genes.GO analysis revealed significant functional categories,including response to LPS.Pathway analysis identified key signaling pathways involved in uveitis,such as cytokine-cytokine receptor interactions.Notably,16 mRNA and 7 lncRNA DEGs emerged as central nodes in the gene correlation network.CONCLUSION:HPS exerts its anti-inflammatory effects through coordinated signaling pathways,offering insights into potential therapeutic targets for managing uveitis.展开更多
Octopuses,due to their flexible arms,marvelous adaptability,and powerful suckers,are able to effortlessly grasp and disengage various objects in the marine surrounding without causing devastation.However,manipulating ...Octopuses,due to their flexible arms,marvelous adaptability,and powerful suckers,are able to effortlessly grasp and disengage various objects in the marine surrounding without causing devastation.However,manipulating delicate objects such as soft and fragile foods underwater require gentle contact and stable adhesion,which poses a serious challenge to now available soft grippers.Inspired by the sucker infundibulum structure and flexible tentacles of octopus,herein we developed a hydraulically actuated hydrogel soft gripper with adaptive maneuverability by coupling multiple hydrogen bond-mediated supramolecular hydrogels and vat polymerization three-dimensional printing,in which hydrogel bionic sucker is composed of a tunable curvature membrane,a negative pressure cavity,and a pneumatic chamber.The design of the sucker structure with the alterable curvature membrane is conducive to realize the reliable and gentle switchable adhesion of the hydrogel soft gripper.As a proof-of-concept,the adaptive hydrogel soft gripper is capable of implement diversified underwater tasks,including gingerly grasping fragile foods like egg yolks and tofu,as well as underwater robots and vehicles that station-keeping and crawling based on switchable adhesion.This study therefore provides a transformative strategy for the design of novel soft grippers that will render promising utilities for underwater exploration soft robotics.展开更多
By analyzing the pollutant concentrations over the urban area and over the rural area of the city of Lanzhou, Gansu Province, China, the relationships between the daytime inversion intensity and the pollutant concentr...By analyzing the pollutant concentrations over the urban area and over the rural area of the city of Lanzhou, Gansu Province, China, the relationships between the daytime inversion intensity and the pollutant concentration in the atmospheric boundary layer （ABL） are studied with the consideration of wind speed and direction, potential temperature, specific humidity profiles, pollutant concentration in the ABL, the surface temperature, and global radiation on the ground. It was shown that the daytime inversion is a key factor in controlling air pollution concentration. A clear and positive feedback process between the daytime inversion intensity and the air pollutants over the city was found through the analysis of influences of climatic and environmental factors. The mechanisms by which the terrain and air pollutants affect the formation of the daytime inversion are discussed. The solar radiation as the essential energy source to maintain the inversion is analyzed, as are various out-forcing factors affecting the inversion and air pollutants. At last, a physical frame of relationships of air pollution with daytime inversion and the local and out-forcing factors over Lanzhou is built.展开更多
The formation and development of weather events has a great impact on the diffusion, accumulation and transport of air pollutants, and causes great changes in the particulate pollution level. It is very important to s...The formation and development of weather events has a great impact on the diffusion, accumulation and transport of air pollutants, and causes great changes in the particulate pollution level. It is very important to study their influence on particulate pollution. Lanzhou is one of the most particulate-polluted cities in China and even in the world. Particulate matter （PM） including TSP, PM〉10, PMzs-10, PM2.5 and PM1.0 concentrations were simultaneously measured during 2005-2007 in Lanzhou to evaluate the influence of three kinds of weather events - dost, precipitation and cold front - on the concentrations of PM with different sizes and detect the temporal evolution. The main results are as follows： （1） the PM pollution in Lanzhou during dust events was very heavy and the rate of increase in the concentration of PM2.5-10 was the highest of the five kinds of particles. During dust-storm events, the highest peaks of the concentrations of fine particles （PM2.5 and PM1.0） occurred 3 hr later than those of coarse particles （PM〉10 and PM/.5-10）. （2） The major effect of precipitation events on PM is wet scavenging. The scavenging rates of particles were closely associated with the kinds of precipitation events. The scavenging rates of TSP, PM〉10 and PMa.5-10 by convective precipitation were several times as high as those caused by frontal precipitation for the same precipitation amount, the reason being the different formation mechanism and precipitation characteristics of the two kinds of precipitation. Moreover, there exists a limiting value for the scavenging rates of particles by precipitation. （3） The major effect of cold-front events on particles is clearance. However, during cold-front passages, the PM concentrations could sometimes rise first and decrease afterwards, which is the critical difference in the influence of cold fronts on the concentrations of particulate pollutants vs. gaseous pollutants.展开更多
The data, measured by a three-wavelength Integrating Nephelometer over Lanzhou City during the winters of 2001/2002 and 2002/2003 respectively, have been analyzed for investigating the scattering properties of atmos...The data, measured by a three-wavelength Integrating Nephelometer over Lanzhou City during the winters of 2001/2002 and 2002/2003 respectively, have been analyzed for investigating the scattering properties of atmospheric aerosols and exploring their relationship and the status of air pollution. The aerosol particle volume distribution is inverted with the measured spectral scattering coe?cients. The results show that the daily variation of the aerosol scattering coe?cients is in a tri-peak shape. The average ratio of backscattering coe?cient to total scattering coe?cient at 550 nm is 0.158; there exists an excellent correlation between the scattering coe?cients and the concentration of PM10. The average ratio of the concentration of PM10 to the scattering coe?cients is 0.37 g m?2, which is contingent on the optical parameters of aerosol particles such as the size distribution, etc.; an algorithm is developed for inverting the volume distribution of aerosol particles by using the histogram and Monte-Carlo techniques, and the test results show that the inversion is reasonable.展开更多
The total emission control method based on atmospheric environmental capacity is the most effective in air pollution mitigation. The atmospheric environmental capacities of SO2 on representative days over Lanzhou are ...The total emission control method based on atmospheric environmental capacity is the most effective in air pollution mitigation. The atmospheric environmental capacities of SO2 on representative days over Lanzhou are estimated using the numerical models RAMS, HYPACT and a linear programming model, according to the national ambient air quality standard of China （NAAQSCHN）. The results show that the fields of meteorological elements and SO2 simulated by the models agree reasonably well with observations. The atmospheric environmental capacity of SO2 over Lanzhou is around 111.7 × 10^3 kg d^-1, and in order to meet the air quality level Ⅱ of the NAAQSCHN, SO2 emissions need to be reduced by 20%.展开更多
Objectives:To examine the relationship between cardiovascular disease risk factors and frailty in a sample of older Chinese adults.Methods:A total of 458 community-dwelling older adults(>65 years)in Lanzhou,Gansu P...Objectives:To examine the relationship between cardiovascular disease risk factors and frailty in a sample of older Chinese adults.Methods:A total of 458 community-dwelling older adults(>65 years)in Lanzhou,Gansu Province of China participated in a cross-sectional survey.Their status was evaluated in terms of frailty phenotype(unintentional weight loss,exhaustion,low activity levels,slowness and weakness).Participants were categorized as not frail,prefrail or frail.Cardiovascular disease risk factors that were assessed included:blood pressure,body mass index,waist circumference,blood glucose,total cholesterol,triglycerides,lowdensity lipoproteins and high-density lipoproteins.Results:Individuals with obesity had an increased risk of prefrailty(OR:2.26;95%CI:1.05,4.84).Hypertension was inversely associated with frailtyamong the participants(OR:0.31;95%CI:0.11,0.87)after adjusting for covariates.Conclusions:The findings suggest that much more attention should be paid to weight control of the elderly in the community for preventing them from transition to prefrailty or frailty.Active prevention and control of cardiovascular diseases among the community-dwelling elder are still of great importance.展开更多
BACKGROUND Most of study regarding periampullary diverticulum(PAD)impact on endoscopic retrograde cholangiopancreatography(ERCP)therapy for choledocholithiasis based on data from one endoscopy center and lacked to com...BACKGROUND Most of study regarding periampullary diverticulum(PAD)impact on endoscopic retrograde cholangiopancreatography(ERCP)therapy for choledocholithiasis based on data from one endoscopy center and lacked to compare the clinical characteristic of choledocholithiasis with PAD from different geographical patients.AIM To compare the choledocholithiasis clinical characteristics between two regional endoscopy centers and analyze impacts of clinical characteristics on ERCP methods for choledocholithiasis patients with PAD.METHODS Patients seen in two endoscopy centers(The First Hospital of Lanzhou University,Lanzhou,Gansu Province,China,and Kyoto Second Red Cross Hospital,Kyoto,Japan)underwent ERCP treatment for the first time between January 2012 and December 2017.The characteristics of choledocholithiasis with PAD were compared between the two centers,and their ERCP procedures and therapeutic outcomes were analyzed.RESULTS A total of 829 out of 3608 patients in the Lanzhou center and 241 out of 1198 in the Kyoto center had choledocholithiasis with PAD.Lots of clinical characteristics were significantly different between the two centers.The common bile duct(CBD)diameter was wider,choledocholithiasis size was lager and multiple CBD stones were more in the Lanzhou center patients than those in the Kyoto center patients(14.8±5.2 mm vs 11.6±4.2 mm,12.2±6.5 mm vs 8.2±5.3 mm,45.3%vs 20.3%,P<0.001 for all).In addition,concomitant diseases,such as acute cholangitis,gallbladder stones,obstructive jaundice,cholecystectomy,and acute pancreatitis,were significantly different between the two centers(P=0.03 to<0.001).In the Lanzhou center,CBD diameter and choledocholithiasis size were lower,and multiple CBD stones and acute cholangitis were less in non-PAD patients than those in PAD patients(13.4±5.1 mm vs 14.8±5.2 mm,10.3±5.4 mm vs 12.2±6.5,39%vs 45.3%,13.9%vs 18.5%,P=0.002 to<0.001).But all these characteristics were not significantly different in the Kyoto center.The proportions of endoscopic sphincterotomy(EST),endoscopic balloon dilatation(EPBD),and EST+EPBD were 50.5%,1.7%,and 42.5%in the Lanzhou center and 90.0%,0.0%,and 0.4%in the Kyoto center,respectively.However,the overall post-ERCP complication rate was not significantly different between the two centers(8.9%in the Lanzhou and 5.8%in the Kyoto.P=0.12).In the Lanzhou center,the difficulty rate in removing CBD stones in PAD was higher than in non-PAD group(35.3%vs 26.0%,P<0.001).But the rate was no significant difference between the two groups in Kyoto center.The residual rates of choledocholithiasis were not significantly different between the two groups in both centers.Post-ERCP complications occurred in 8.9%of the PAD patients and 8.1%of the non-PAD patients in the Lanzhou Center,and it occurred in 5.8%in PAD patients and 10.0%in non-PAD patients in the Kyoto center,all P>0.05.CONCLUSION Many clinical characteristics of choledocholithiasis patients with PAD were significantly different between the Lanzhou and Kyoto centers.The patients had larger and multiple stones,wider CBD diameter,and more possibility of acute cholangitis and obstructive jaundice in the Lanzhou center than those in the Kyoto center.The ERCP procedures to manage native duodenal papilla were different depending on the different clinical characteristics while the overall post-ERCP complications were not significantly different between the two centers.The stone residual rate and post-ERCP complications were not significantly different between choledocholithiasis patients with PAD and without PAD in each center.展开更多
Rapid industrialization and urbanization have led to the most serious habitat degradation in China,especially in the loess hilly area of the Yellow River Basin,where the ecological environment is relatively fragile.Th...Rapid industrialization and urbanization have led to the most serious habitat degradation in China,especially in the loess hilly area of the Yellow River Basin,where the ecological environment is relatively fragile.The contradiction between economic development and ecological environment protection has aroused widespread concern.In this study,we used the habitat quality of Integrated Valuation of Ecosystem Services and Tradeoffs(InVEST-HQ)model at different scales to evaluate the dynamic evolution characteristics of habitat quality in Lanzhou City,Gansu Province of China.The spatiotemporal variations of habitat quality were analyzed by spatial autocorrelation.A Geographical Detector(Geodetector)model was used to explore the driving factors that influencing the spatial differentiation of habitat quality,including natural factors,socio-economic factors,and ecological protection factors.The results showed that the habitat quality index of Lanzhou City decreased from 0.4638 to 0.4548 during 2000-2018.The areas with reduced the habitat quality index were mainly located in the Yellow River Basin and Qinwangchuan Basin,where are the main urban areas and the new economic development areas,respectively.The spatial distribution of habitat quality presented a trend of high in the surrounding areas and low in the middle,and showed a significant positive spatial autocorrelation.With the increase of study scale,the spatial distribution of habitat quality changed from concentrated to dispersed.The spatial differentiation of habitat quality in the study area was the result of multiple factors.Among them,topographic relief and slope were the key factors.The synergistic enhancement among these driving factors intensified the spatial differentiation of habitat quality.The findings of this study can provide a scientific basis for land resources utilization and ecosystem restoration in the arid and semi-arid land.展开更多
文摘After more than 20 years of development, great changes have taken place in Yuzhong Campus of Lanzhou University. Standing at the new starting point of the construction of "double first-class" universities, the future development of campus is very important. Using the high-resolution images taken by Landsat and unmanned aerial vehicles. Based on remote sensing and GIS analysis technology, this paper analyzes the land use change, road system, plot ratio, etc. of Yuzhong Campus in the past 20 years, summarizes the development law of the campus over the years, and based on this, provides suggestions for future development, which has certain practical significance for the future construction of Yuzhong Campus and ecological innovation city.
基金Under the auspices of National Natural Science Foundation of China(No.42401232,72050001)Natural Science Foundation of Gansu Province(No.24JRRA419)Research Funds for Blue Green Infrastructure Planning and Ecological Restoration in Mining Cities(No.071124044/(24)0315)。
文摘Urban open spaces(UOS)play a crucial role in enhancing city livability and resident well-being,yet there remains a gap in utilizing social media to analyze changes in UOS utilization across different COVID(Corona Virus Disease)-19 phases.Our research applied Sina Weibo data to scrutinize UOS engagement across pre-pandemic(2019),pandemic(2021),and post-pandemic(2023)periods in Lanzhou City,China,revealing evolving spatiotemporal patterns and highlighting the pandemic's impact on UOS usage.Initially,scenic mountains and urban parks dominated visitor preferences in 2019.However,during the pandemic,there was a trend towards destinations that combined elements of tourism,business,entertainment,and culture,reflecting a growing appetite for diverse experiences.Despite this shift,the post-pandemic period did not see a complete return to pre-pandemic travel patterns,with a noticeable decline in visits to traditional green open spaces during lockdowns.We identified key attractions in main urban areas,highlighting geographical variations in tourism and Cultural Ecosystem Services(CES)distribution that warrant further attention.The post-pandemic landscape reveals a resurging interest in green-blue spaces and nature-focused tourism,highlighting a continued preference for cultural and natural experiences,and emphasizing the need to harmonize development with the preservation of natural and cultural heritage.This study introduces the use of social media data across pandemic phases to guide UOS management,offering insights for creating resilient,multifunctional urban spaces that address public needs and enhance community well-being.
文摘A restoration concept has been developed based on the Baiyun Taoist Temple Map found in the Continuation of the Gaolan County Annals.This study systematically analyzes the architectural features of Baiyun Taoist Temple in Lanzhou during the Daoguang period of the Qing Dynasty from three perspectives:overall layout,spatial design,and garden artistic conception.The analysis offers a representative case for understanding the spatial organization principles and cultural connotation of Taoist architecture in the Lanzhou region during the Qing Dynasty.
文摘Soundscape has been attracting more attention as a key landscape component,its effect on environmental perception relies not only on the physical attributes of sounds,but also the co-influence and interaction of sound sources and surroundings.To systematically identify the objective soundscape characteristics in the wetland park and the influence factors,this paper applied sound walk method to investigate the sound source types,sound pressure level(SPL),and objects and subjects’soundscape perception.The results showed that artificial sounds accounted for the most of soundscapes in the park(60%),natural sounds accounted for 25%,life sounds about 15%.Among the natural sounds,bird chirping and frog croaking were the favorite of users;the mean equivalent continuous A sound level of each measure point in the park was 50.2 dB,complying with the national standard limit value.Optimization of the sound environment in the wetland park should comprehensively consider the landscape layout,current characteristics and users’requirements,relevant designs and management strategies are of great practical significance for improving the quality of soundscape and the comfort degree of overall environment.
基金funded by the Strategic Priority Research Program of the Chinese Academy of Sciences(Grant No.XDB0950000)the NSFC(Grant No.42201155+2 种基金4240114742201137)the State Key Laboratory of Cryospheric Science and Frozen Soil Engineering(CSFSE-ZQ-2410).
文摘The Yellow River(YR),China’s second-longest river,remains understudied regarding its greenhouse gases(GHGs)emissions,particularly the impacts of urban drainage ditches and wastewater treatment facilities on regional GHGs dynamics.This study investigated methane(CH_(4))and carbon dioxide(CO_(2))concentrations,fluxes and stable carbon isotopes(δ^(13)C-CH_(4)and δ^(13)C-CO_(2))across six main stream,three ditches,and one wastewater treatment site along the upper Lanzhou section of the YR,spanning from the urban entrance(36.176°N,103.449°E)to the exit of Lanzhou city(36.056°N,104.020°E).Measured CH_(4)diffusion fluxes in mainstem sites ranged from 0.01 to 2.58 mmol·m^(−2)·d^(−1)(mean:0.36 mmol·m^(−2)·d^(−1)),while ebullitive fluxes(gas bubbles)ranged from 0.01 to 18.89 mmol·m^(−2)·d^(−1)(mean:0.90 mmol·m^(−2)·d^(−1)).CO_(2)diffusion fluxes varied between 9.16–92.80 mmol·m^(−2)·d^(−1)(averaged:39.11 mmol·m^(−2)·d^(−1))at these locations.Ebullition(bubble)fluxes accounted for 53.1%±22.4%(range:9.0%to 98.4%)to total CH_(4)emissions(diffusion plus ebullition),with peak fluxes occurring during summer,indicating its significance as a CH_(4)transport mechanism.Notably,both diffusion CH_(4)and CO_(2)fluxes and ebullitive CH_(4)rates at ditch sites substantially exceeded those in mainstream reaches.The lowest CH_(4)and highest CO_(2)concentrations were observed at a wastewater treatment site,likely resulting from the removal of high organic loads.Acetoclastic methanogenesis—the process converting acetate-derived methyl groups to CH_(4)—was identified as the dominant production pathway in both mainstream and ditch environments.CH_(4)and CO_(2)flux magnitudes in the upper YR(Lanzhou section)were comparable to those observed in subtropical Yangtze River tributaries.These results demonstrate that anthropogenic influences significantly enhance CO_(2)/CH_(4)emissions,and the lateral exports of dissolved carbon(DIC and DOC)in the main stream site was quantified.,which cannot be overlooked.The findings emphasize the critical need to account for pronounced spatiotemporal variations in arid-region GHG fluxes to improve basin-scale estimates for the YR.
文摘Three zinc(Ⅱ),nickel(Ⅱ),and cadmium(Ⅱ)complexes,namely[Zn(μ-Htpta)(py)_(2)]n(1),[Ni(H_(2)biim)2(H_(2)O)2][Ni(tpta)(H_(2)biim)2(H_(2)O)]2·3H_(2)O(2),and[Cd_(3)(μ4-tpta)2(μ-dpe)_(3)]_(n)(3),have been constructed hydrothermally at 160℃ using H_(3)tpta([1,1':3',1″-terphenyl]-4,4',5'-tricarboxylic acid),py(pyridine),H_(2)biim(2,2'-biimidazole),dpe(1,2-di(4-pyridyl)ethylene),and zinc,nickel and cadmium chlorides,resulting in the formation of stable crystalline solids which were subsequently analyzed using infrared spectroscopy,element analysis,thermogravimetric analysis,as well as structural analyses conducted via single-crystal X-ray diffraction.The findings from these single-crystal Xray diffraction studies indicate that complexes 1-3 form crystals within the monoclinic system P2_(1)/c space group(1)or triclinic system P1 space group(2 and 3),and possess 1D,0D,and 3D structures,respectively.Complex 1 demonstrated substantial catalytic efficiency and excellent reusability as a heterogeneous catalyst in the reaction of Knoevenagel condensation under ambient temperature conditions.In addition,complex 1 also showcased notable anti-wear performance when used in polyalphaolefin synthetic lubricants.CCDC:2449810,1;2449811,2;2449812,3.
基金supported by Cuiying Scientific and Technological Innovation Program of Second Hospital of Lanzhou University,Nos.CY2023-QN-B18(to YD),2020QN-16(to YZ)the Natural Science Foundation of Gansu Province,No.22JR11RA082(to YZ)Key R&D Plan of Gansu Provincial Department of Science and Technology-Social Development Projects,No.23YFFA0043(to XK).
文摘Spinal cord ischemia-reperfusion injury,a severe form of spinal cord damage,can lead to sensory and motor dysfunction.This injury often occurs after traumatic events,spinal cord surgeries,or thoracoabdominal aortic surgeries.The unpredictable nature of this condition,combined with limited treatment options,poses a significant burden on patients,their families,and society.Spinal cord ischemia-reperfusion injury leads to reduced neuronal regenerative capacity and complex pathological processes.In contrast,mitophagy is crucial for degrading damaged mitochondria,thereby supporting neuronal metabolism and energy supply.However,while moderate mitophagy can be beneficial in the context of spinal cord ischemia-reperfusion injury,excessive mitophagy may be detrimental.Therefore,this review aims to investigate the potential mechanisms and regulators of mitophagy involved in the pathological processes of spinal cord ischemia-reperfusion injury.The goal is to provide a comprehensive understanding of recent advancements in mitophagy related to spinal cord ischemia-reperfusion injury and clarify its potential clinical applications.
基金supported by the research start-up funds for invited doctor of Lanzhou University of Technology under Grant 14/062402。
文摘In the context of modern software development characterized by increasing complexity and compressed development cycles,traditional static vulnerability detection methods face prominent challenges including high false positive rates and missed detections of complex logic due to their over-reliance on rule templates.This paper proposes a Syntax-Aware Hierarchical Attention Network(SAHAN)model,which achieves high-precision vulnerability detection through grammar-rule-driven multi-granularity code slicing and hierarchical semantic fusion mechanisms.The SAHAN model first generates Syntax Independent Units(SIUs),which slices the code based on Abstract Syntax Tree(AST)and predefined grammar rules,retaining vulnerability-sensitive contexts.Following this,through a hierarchical attention mechanism,the local syntax-aware layer encodes fine-grained patterns within SIUs,while the global semantic correlation layer captures vulnerability chains across SIUs,achieving synergistic modeling of syntax and semantics.Experiments show that on benchmark datasets like QEMU,SAHAN significantly improves detection performance by 4.8%to 13.1%on average compared to baseline models such as Devign and VulDeePecker.
基金supported by the National Natural Science Foundation of China(Nos.42305089 and 42175106)the Self-supporting Program of Guangzhou Laboratory(No.SRPG22-007)+1 种基金the Youth Science and Technology Fund Project of Gansu(No.22JR5RA512)the Fundamental Research Funds for the Central Universities(No.lzujbky-2022-pd05).
文摘Ambient fine particulate matter(PM_(2.5))pollution causes the largest environmental health risk globally,yet ex-posure levels and the resulting health risks vary across countries with different income levels.Global wealth inequality has intensified in recent years,yet the relationship between wealth inequality and health risks related to PM_(2.5) pollution remains poorly understood.In this study,we evaluated the global mortality and health cost at-tributable to PM_(2.5) exposure from 2017 to 2021,and analyzed the relationship between wealth inequality,PM_(2.5) pollution,and the associated health risks across regions with varying economic levels.We found a consistent decline in mortalities and health costs attributable to PM_(2.5) exposure from 2017 to 2020,followed by a rebound after 2020,driven primarily by the resurgence of PM_(2.5) concentrations and a deceleration in the reduction of baseline mortality rates.We also found that the average PM_(2.5) concentration and associated risks decrease as domestic wealth inequality decreases and national income level increases.However,regions with extremely high levels of wealth inequality consistently show lower national average PM_(2.5) concentrations and health risks.These findings highlight the need to consider healthcare security during emergencies,as well as policy fairness across economic regions,in the formulation of global PM_(2.5) pollution control measures to promote sustainable,more equitable economic growth and coordinated air pollution management.
基金supported by the Swedish Research Council(Vetenskapsradet,Grant No.202203129)the Project of Youth Science and Technology Fund of Gansu Province(Grant No.24JRRA439)partially funded by the Swedish Research Council(Vetenskapsradet,Grant No.2022-06725)。
文摘This study investigates the impact of vegetation-climate feedback on the global land monsoon system during the Last Interglacial(LIG,127000 years BP)and the mid-Holocene(MH,6000 years BP)using the earth system model EC-Earth3.Our findings indicate that vegetation changes significantly influence the global monsoon area and precipitation patterns,especially in the North African and Indian monsoon regions.The North African monsoon region experienced the most substantial increase in vegetation during both the LIG and MH,resulting in significant increases in monsoonal precipitation by 9.8%and 6.0%,respectively.The vegetation feedback also intensified the Saharan Heat Low,strengthened monsoonal flows,and enhanced precipitation over the North African monsoon region.In contrast,the Indian monsoon region exhibited divergent responses to vegetation changes.During the LIG,precipitation in the Indian monsoon region decreased by 2.2%,while it increased by 1.6%during the MH.These differences highlight the complex and region-specific impacts of vegetation feedback on monsoon systems.Overall,this study demonstrates that vegetation feedback exerts distinct influences on the global monsoon during the MH and LIG.These findings highlight the importance of considering vegetation-climate feedback in understanding past monsoon variability and in predicting future climate change impacts on monsoon systems.
基金National Natural Science Foundation of China,No.42501182The Open Foundation of Key Laboratory of Western China’s Environmental System,Ministry of Education,Lanzhou Universitythe Fundamental Research Funds for the Central Universities,No.lzujbky-2024-jdzx01。
文摘Aeolian deposits across the Yarlung Zangbo River Basin on the southern Tibetan Plateau record the landscape and atmospheric evolution of Earth's Third Pole.The complex mountain-basin system exhibits nonlinear responses to climate forcing,complicating the interpretation of its high-altitude environmental dynamics.Investigating the magnetic enhancement mechanism of aeolian deposits offers an opportunity to decipher climate signals.Our analysis of three aeolian sections from the basin indicates that magnetic minerals are predominantly low-coercivity ferrimagnetic minerals,and grain sizes fine from upper to lower reaches due to climate shifts from arid to humid.Magnetic enhancement in the upper reaches primarily originates from dust input,while dust input and pedogenesis contribute variably over time in the middle and lower reaches.Similar complex patterns occur in the Ili basin,a mountain-basin system in northwestern China.They differ from the Chinese Loess Plateau,where long-distance-transported dust is well-mixed and the pedogenic enhancement model is applied,and desert peripheries where short-distance dust is transported and the dust input model is applied.We summarize the magnetic enhancement mechanisms in various settings and offer a new framework for applying magnetic techniques in paleoclimate reconstruction within global mountain-basin systems,which highlights the need for caution in interpreting their magnetic susceptibility records.
基金Supported by the National Natural Science Fundation of China(No.82101107No.81471575).
文摘AIM:To identify key genes and inflammatory signaling pathways involved in the anti-inflammatory effects of Hedysarum polybotrys polysaccharide(HPS)in a rat model of endotoxin-induced uveitis(EIU).METHODS:EIU was induced in Wistar rats through subcutaneous injection of lipopolysaccharide(LPS,200μg)and the rats were then randomly assigned to EIU group(n=5)and the HPS intervention group(n=5).HPS(400 mg/kg,intraperitoneally)or its carrier was administered 24h and 1h prior to EIU induction.Eyes were examined and enucleated 24h post-induction,and total RNA was extracted from the iris-ciliary body.Gene expression microarrays were used to identify differentially expressed genes(DEGs),followed by bioinformatics analyses,including gene ontology(GO)and pathway analysis.Key findings were not experimentally validated at the mRNA or protein level.RESULTS:A total of 322 DEGs were identified,comprising 254 mRNA and 68 lncRNA genes.GO analysis revealed significant functional categories,including response to LPS.Pathway analysis identified key signaling pathways involved in uveitis,such as cytokine-cytokine receptor interactions.Notably,16 mRNA and 7 lncRNA DEGs emerged as central nodes in the gene correlation network.CONCLUSION:HPS exerts its anti-inflammatory effects through coordinated signaling pathways,offering insights into potential therapeutic targets for managing uveitis.
基金the financial support from the Strategic Priority Research Program of the Chinese Academy of Sciences (XDB0470303)the National Key Research and Development Program of China (2022YFB4600101)+5 种基金the National Natural Science Foundation of China (52175201)the Research Program of Science and Technology Department of Gansu Province (24JRRA059, 24JRRA044, and 24YFFA014)the Science Fund of Shandong Laboratory of Advanced Materials and Green Manufacturing at Yantai (AMGM2024F12)the Major Program (ZYFZFX-2) of the Lanzhou Institute of Chemical Physics, CASthe Special Research Assistant Project of the Chinese Academy of Sciencesthe Oasis Scholar of Shihezi University
文摘Octopuses,due to their flexible arms,marvelous adaptability,and powerful suckers,are able to effortlessly grasp and disengage various objects in the marine surrounding without causing devastation.However,manipulating delicate objects such as soft and fragile foods underwater require gentle contact and stable adhesion,which poses a serious challenge to now available soft grippers.Inspired by the sucker infundibulum structure and flexible tentacles of octopus,herein we developed a hydraulically actuated hydrogel soft gripper with adaptive maneuverability by coupling multiple hydrogen bond-mediated supramolecular hydrogels and vat polymerization three-dimensional printing,in which hydrogel bionic sucker is composed of a tunable curvature membrane,a negative pressure cavity,and a pneumatic chamber.The design of the sucker structure with the alterable curvature membrane is conducive to realize the reliable and gentle switchable adhesion of the hydrogel soft gripper.As a proof-of-concept,the adaptive hydrogel soft gripper is capable of implement diversified underwater tasks,including gingerly grasping fragile foods like egg yolks and tofu,as well as underwater robots and vehicles that station-keeping and crawling based on switchable adhesion.This study therefore provides a transformative strategy for the design of novel soft grippers that will render promising utilities for underwater exploration soft robotics.
基金supported by the National Science Foundation of China (Grant Nos.40830957 and 40575006)the joint research project of Gansu Province and Chinese Academy of Science named"Study on Atmosphere Pollution and its Countermeasure of Lanzhou City"
文摘By analyzing the pollutant concentrations over the urban area and over the rural area of the city of Lanzhou, Gansu Province, China, the relationships between the daytime inversion intensity and the pollutant concentration in the atmospheric boundary layer （ABL） are studied with the consideration of wind speed and direction, potential temperature, specific humidity profiles, pollutant concentration in the ABL, the surface temperature, and global radiation on the ground. It was shown that the daytime inversion is a key factor in controlling air pollution concentration. A clear and positive feedback process between the daytime inversion intensity and the air pollutants over the city was found through the analysis of influences of climatic and environmental factors. The mechanisms by which the terrain and air pollutants affect the formation of the daytime inversion are discussed. The solar radiation as the essential energy source to maintain the inversion is analyzed, as are various out-forcing factors affecting the inversion and air pollutants. At last, a physical frame of relationships of air pollution with daytime inversion and the local and out-forcing factors over Lanzhou is built.
基金supported by the National Special Project for Commonweal Industry in China (No. GY-HY201006023,GYHY201106034)the National Support Projects for Science and Technology in China (No.2009BAC53B02)+2 种基金the Project of National Natural Science Foundation of China (No. 41075103)the Application and Foundation Research Program of Sichuan Province (No.2009JY0116)the Project of the Scientific Research Foundation of CUIT (No. KYTZ201008)
文摘The formation and development of weather events has a great impact on the diffusion, accumulation and transport of air pollutants, and causes great changes in the particulate pollution level. It is very important to study their influence on particulate pollution. Lanzhou is one of the most particulate-polluted cities in China and even in the world. Particulate matter （PM） including TSP, PM〉10, PMzs-10, PM2.5 and PM1.0 concentrations were simultaneously measured during 2005-2007 in Lanzhou to evaluate the influence of three kinds of weather events - dost, precipitation and cold front - on the concentrations of PM with different sizes and detect the temporal evolution. The main results are as follows： （1） the PM pollution in Lanzhou during dust events was very heavy and the rate of increase in the concentration of PM2.5-10 was the highest of the five kinds of particles. During dust-storm events, the highest peaks of the concentrations of fine particles （PM2.5 and PM1.0） occurred 3 hr later than those of coarse particles （PM〉10 and PM/.5-10）. （2） The major effect of precipitation events on PM is wet scavenging. The scavenging rates of particles were closely associated with the kinds of precipitation events. The scavenging rates of TSP, PM〉10 and PMa.5-10 by convective precipitation were several times as high as those caused by frontal precipitation for the same precipitation amount, the reason being the different formation mechanism and precipitation characteristics of the two kinds of precipitation. Moreover, there exists a limiting value for the scavenging rates of particles by precipitation. （3） The major effect of cold-front events on particles is clearance. However, during cold-front passages, the PM concentrations could sometimes rise first and decrease afterwards, which is the critical difference in the influence of cold fronts on the concentrations of particulate pollutants vs. gaseous pollutants.
基金the National Natural Science Foundation of China(Grant Nos.49875027,40275039).
文摘The data, measured by a three-wavelength Integrating Nephelometer over Lanzhou City during the winters of 2001/2002 and 2002/2003 respectively, have been analyzed for investigating the scattering properties of atmospheric aerosols and exploring their relationship and the status of air pollution. The aerosol particle volume distribution is inverted with the measured spectral scattering coe?cients. The results show that the daily variation of the aerosol scattering coe?cients is in a tri-peak shape. The average ratio of backscattering coe?cient to total scattering coe?cient at 550 nm is 0.158; there exists an excellent correlation between the scattering coe?cients and the concentration of PM10. The average ratio of the concentration of PM10 to the scattering coe?cients is 0.37 g m?2, which is contingent on the optical parameters of aerosol particles such as the size distribution, etc.; an algorithm is developed for inverting the volume distribution of aerosol particles by using the histogram and Monte-Carlo techniques, and the test results show that the inversion is reasonable.
基金the National Natural Science Foundation of China （Grant No. 40305020）.
文摘The total emission control method based on atmospheric environmental capacity is the most effective in air pollution mitigation. The atmospheric environmental capacities of SO2 on representative days over Lanzhou are estimated using the numerical models RAMS, HYPACT and a linear programming model, according to the national ambient air quality standard of China （NAAQSCHN）. The results show that the fields of meteorological elements and SO2 simulated by the models agree reasonably well with observations. The atmospheric environmental capacity of SO2 over Lanzhou is around 111.7 × 10^3 kg d^-1, and in order to meet the air quality level Ⅱ of the NAAQSCHN, SO2 emissions need to be reduced by 20%.
基金supported by the National Natural Science Foundation of China[grant number 71804064].
文摘Objectives:To examine the relationship between cardiovascular disease risk factors and frailty in a sample of older Chinese adults.Methods:A total of 458 community-dwelling older adults(>65 years)in Lanzhou,Gansu Province of China participated in a cross-sectional survey.Their status was evaluated in terms of frailty phenotype(unintentional weight loss,exhaustion,low activity levels,slowness and weakness).Participants were categorized as not frail,prefrail or frail.Cardiovascular disease risk factors that were assessed included:blood pressure,body mass index,waist circumference,blood glucose,total cholesterol,triglycerides,lowdensity lipoproteins and high-density lipoproteins.Results:Individuals with obesity had an increased risk of prefrailty(OR:2.26;95%CI:1.05,4.84).Hypertension was inversely associated with frailtyamong the participants(OR:0.31;95%CI:0.11,0.87)after adjusting for covariates.Conclusions:The findings suggest that much more attention should be paid to weight control of the elderly in the community for preventing them from transition to prefrailty or frailty.Active prevention and control of cardiovascular diseases among the community-dwelling elder are still of great importance.
文摘BACKGROUND Most of study regarding periampullary diverticulum(PAD)impact on endoscopic retrograde cholangiopancreatography(ERCP)therapy for choledocholithiasis based on data from one endoscopy center and lacked to compare the clinical characteristic of choledocholithiasis with PAD from different geographical patients.AIM To compare the choledocholithiasis clinical characteristics between two regional endoscopy centers and analyze impacts of clinical characteristics on ERCP methods for choledocholithiasis patients with PAD.METHODS Patients seen in two endoscopy centers(The First Hospital of Lanzhou University,Lanzhou,Gansu Province,China,and Kyoto Second Red Cross Hospital,Kyoto,Japan)underwent ERCP treatment for the first time between January 2012 and December 2017.The characteristics of choledocholithiasis with PAD were compared between the two centers,and their ERCP procedures and therapeutic outcomes were analyzed.RESULTS A total of 829 out of 3608 patients in the Lanzhou center and 241 out of 1198 in the Kyoto center had choledocholithiasis with PAD.Lots of clinical characteristics were significantly different between the two centers.The common bile duct(CBD)diameter was wider,choledocholithiasis size was lager and multiple CBD stones were more in the Lanzhou center patients than those in the Kyoto center patients(14.8±5.2 mm vs 11.6±4.2 mm,12.2±6.5 mm vs 8.2±5.3 mm,45.3%vs 20.3%,P<0.001 for all).In addition,concomitant diseases,such as acute cholangitis,gallbladder stones,obstructive jaundice,cholecystectomy,and acute pancreatitis,were significantly different between the two centers(P=0.03 to<0.001).In the Lanzhou center,CBD diameter and choledocholithiasis size were lower,and multiple CBD stones and acute cholangitis were less in non-PAD patients than those in PAD patients(13.4±5.1 mm vs 14.8±5.2 mm,10.3±5.4 mm vs 12.2±6.5,39%vs 45.3%,13.9%vs 18.5%,P=0.002 to<0.001).But all these characteristics were not significantly different in the Kyoto center.The proportions of endoscopic sphincterotomy(EST),endoscopic balloon dilatation(EPBD),and EST+EPBD were 50.5%,1.7%,and 42.5%in the Lanzhou center and 90.0%,0.0%,and 0.4%in the Kyoto center,respectively.However,the overall post-ERCP complication rate was not significantly different between the two centers(8.9%in the Lanzhou and 5.8%in the Kyoto.P=0.12).In the Lanzhou center,the difficulty rate in removing CBD stones in PAD was higher than in non-PAD group(35.3%vs 26.0%,P<0.001).But the rate was no significant difference between the two groups in Kyoto center.The residual rates of choledocholithiasis were not significantly different between the two groups in both centers.Post-ERCP complications occurred in 8.9%of the PAD patients and 8.1%of the non-PAD patients in the Lanzhou Center,and it occurred in 5.8%in PAD patients and 10.0%in non-PAD patients in the Kyoto center,all P>0.05.CONCLUSION Many clinical characteristics of choledocholithiasis patients with PAD were significantly different between the Lanzhou and Kyoto centers.The patients had larger and multiple stones,wider CBD diameter,and more possibility of acute cholangitis and obstructive jaundice in the Lanzhou center than those in the Kyoto center.The ERCP procedures to manage native duodenal papilla were different depending on the different clinical characteristics while the overall post-ERCP complications were not significantly different between the two centers.The stone residual rate and post-ERCP complications were not significantly different between choledocholithiasis patients with PAD and without PAD in each center.
基金This research was supported by the National Natural Science Foundation of China(41961029)the Gansu Construction Science and Technology Soft Science Project of China(JK2022-16).
文摘Rapid industrialization and urbanization have led to the most serious habitat degradation in China,especially in the loess hilly area of the Yellow River Basin,where the ecological environment is relatively fragile.The contradiction between economic development and ecological environment protection has aroused widespread concern.In this study,we used the habitat quality of Integrated Valuation of Ecosystem Services and Tradeoffs(InVEST-HQ)model at different scales to evaluate the dynamic evolution characteristics of habitat quality in Lanzhou City,Gansu Province of China.The spatiotemporal variations of habitat quality were analyzed by spatial autocorrelation.A Geographical Detector(Geodetector)model was used to explore the driving factors that influencing the spatial differentiation of habitat quality,including natural factors,socio-economic factors,and ecological protection factors.The results showed that the habitat quality index of Lanzhou City decreased from 0.4638 to 0.4548 during 2000-2018.The areas with reduced the habitat quality index were mainly located in the Yellow River Basin and Qinwangchuan Basin,where are the main urban areas and the new economic development areas,respectively.The spatial distribution of habitat quality presented a trend of high in the surrounding areas and low in the middle,and showed a significant positive spatial autocorrelation.With the increase of study scale,the spatial distribution of habitat quality changed from concentrated to dispersed.The spatial differentiation of habitat quality in the study area was the result of multiple factors.Among them,topographic relief and slope were the key factors.The synergistic enhancement among these driving factors intensified the spatial differentiation of habitat quality.The findings of this study can provide a scientific basis for land resources utilization and ecosystem restoration in the arid and semi-arid land.
