Meeting China's burgeoning food demand while safeguarding the resources and environmental long-term development is a critical challenge for the sustainable food systems of this century.China's accelerated food...Meeting China's burgeoning food demand while safeguarding the resources and environmental long-term development is a critical challenge for the sustainable food systems of this century.China's accelerated food imports have far-reaching implications for global resource allocation and environmental development.Hence,detailed information regarding China's food trade resource-environmental impacts is imperative for the design of effective policies that promote environmental mitigation and resource conservation.This study estimated the spatial transfers of virtual water trade(VWT),virtual land trade(VLT),and virtual GHG emission trade(VGT)embodied in China's food trade.Findings indicate that the VWT,VLT,and VGT transfers embodied in China's food trade increased by 10.4%,9.8%,and 15.2%annually.It is more important to mention that virtual water import(VWI)and virtual land import(VLI)saved 119.5×10~9m^(3)of global water resources and 29.5 Mha of land resources,respectively,but virtual GHG emission import(VGI)increased global 13 Mt CO_(2)-eq GHG emissions.The divergent impacts of China's food import on global food sustainability stem from variations in virtual water content,yields and emission intensities.Moreover,significant differences in sustainability scores were found among the top 15 importing countries,indicating that China's food trade contributes to the deepening of global food system sustainability.This study highlights the need for a multifaceted approach that considers the various environmental impacts of food trade.China is therefore encouraged to fully integrate the benefits of resource and environmental conservation into its sustainable food trade strategy,restructuring the food system to ensure the long-term nourishment of its large population.展开更多
The monofloral honey derived from Bauhinia championii(Benth.)Benth.(MH-Bc)possesses significant nutritional and bioactive value,making it highly suitable for commercial exploitation.However,the poorly defined characte...The monofloral honey derived from Bauhinia championii(Benth.)Benth.(MH-Bc)possesses significant nutritional and bioactive value,making it highly suitable for commercial exploitation.However,the poorly defined characteristics and unknown composition have hindered MH-Bc product development.In this study,we employed a combination of untargeted and targeted mass spectrometry analyses to characterize MH-Bc honey.As a result,4,7,8-trimethoxydibenzo[b,d]furan-3-ol(TDBF)was identified as a robust chemical marker for distinguishing MH-Bc from other types of honey.This specific marker was detected in both MH-Bc and the Bc plant but was absent in other honey varieties.Furthermore,a targeted mass spectrometry quantitative method was developed and validated to accurately determine the content of TDBF in honey samples.Overall,the presence of TDBF serves as a discerning indicator for future commercial MH-Bc products.展开更多
In the field of organic solar cells(OSCs),side-chain engineering is a key strategy for developing high-performance non-fullerene small molecule acceptors(SMAs),which could adjust the material solubility and modulate t...In the field of organic solar cells(OSCs),side-chain engineering is a key strategy for developing high-performance non-fullerene small molecule acceptors(SMAs),which could adjust the material solubility and modulate the intermolecular stacking properties,profoundly impacting the film morphology and thus acting on the final power conversion efficiency(PCE) of the materials.In this study,two asymmetric acceptor molecules,Qx-Ph Br-BO and Qx-Ph Br-X,were synthesized by migrating the branching site of the outer side chain from the β-site to the γ-site.The branching site located at the γ-site could reduce the steric-hindrance effect and enhance the molecular aggregation behavior,giving rise to redshifted absorption and tight π-π stacking.Morphology analysis shows that the Qx-Ph Br-X-based devices have smoother surfaces and a phase-separated structure,which is more favorable for charge transport and extraction.The Qx-Ph Br-X-based devices exhibit balanced hole-electron mobility,efficient exciton dissociation,and low charge recombination.As a result,Qx-Ph Br-X with γ-site branching exhibits superior photovoltaic performance with a PCE of 17.16 %,which is significantly higher than that of Qx-Ph Br-BO at 16.28 %.These results highlight the importance of side-chain modifications for optimizing OSC efficiency and provide an important reference for precise tuning of side-chain structures in future molecular design.展开更多
Gene flow patterns and the genetic structure of domesticated crops like cotton are not well understood.Furthermore,marker-assisted breeding of cotton has lagged far behind that of other major crops because the loci as...Gene flow patterns and the genetic structure of domesticated crops like cotton are not well understood.Furthermore,marker-assisted breeding of cotton has lagged far behind that of other major crops because the loci associated with cotton traits such as fiber yield and quality have scarcely been identified.In this study,we used 19 microsatellites to first determine the population genetic structure and patterns of gene flow of superior germplasm resources in upland cotton.We then used association analysis to identify which markers were associated with 15 agronomic traits(including ten yield and five fiber quality traits).The results showed that the upland cotton accessions have low levels of genetic diversity(polymorphism information content=0.427),although extensive gene flow occurred among different ecological and geographic regions.Bayesian clustering analysis indicated that the cotton resources used in this study did not belong to obvious geographic populations,which may be the consequence of a single source of domestication followed by frequent genetic introgression mediated by human transference.A total of 82 maker-trait associations were examined in association analysis and the related ratios for phenotypic variations ranged from 3.04% to 47.14%.Interestingly,nine SSR markers were detected in more than one environmental condition.In addition,14 SSR markers were co-associated with two or more different traits.It was noteworthy that NAU4860 and NAU5077 markers detected at least in two environments were simultaneously associated with three fiber quality traits(uniformity index,specific breaking strength and micronaire value).In conclusion,these findings provide new insights into the population structure and genetic exchange pattern of cultivated cotton accessions.The quantitative trait loci of domesticated cotton identified will also be very useful for improvement of yield and fiber quality of cotton in molecular breeding programs.展开更多
Different types of dominance hierarchies reflect different social relationships in primates. In this study, we clarified the hierarchy and social relationships in a one-male unit of captive Rhinopithecus bieti observe...Different types of dominance hierarchies reflect different social relationships in primates. In this study, we clarified the hierarchy and social relationships in a one-male unit of captive Rhinopithecus bieti observed between August 1998 and March 1999. Mean frequency of agonistic behaviour among adult females was 0.13 interactions per hour. Adult females exhibited a linear hierarchy with a reversal of 10.9%, indicating an unstable relationship; therefore, R. bieti appears to be a relaxed/tolerant species. The lack of a relationship between the agonistic ratio of the adult male towards adult females and their ranks indicated that males did not show increased aggression towards low-ranking females. Differentiated female affiliative relationships were loosely formed in terms of the male, and to some extent influenced by female estrus, implying that relationships between the male and females is influenced by estrus and not rank alone. A positive correlation between the agonistic ratio of adult females and their ranks showed that the degree to which one female negatively impacted others decreased with reduction in rank. Similarly, a positive correlation between the agonistic ratio of females and differences in rank suggests that a female had fewer negative effects on closely ranked individuals than distantly ranked ones. These data indicate that rank may influence relationships between females. A steeper slope of regression between the agonistic ratio and inter-female rank differences indicated that the extent of the power difference in high-ranking females exerting negative effects on low-ranking ones was larger during the mating season than the birth season, suggesting that rank may influence the mating success of females.展开更多
Safeguarding the elderly population in the countryside is an inherent requirement for alleviating social conflicts in rural areas and effectively carrying out China’s Rural Revitalization.The existing spatial mismatc...Safeguarding the elderly population in the countryside is an inherent requirement for alleviating social conflicts in rural areas and effectively carrying out China’s Rural Revitalization.The existing spatial mismatch between rural elderly service facilities and pop-ulation distribution in China aggravates the imbalance of facility resource space,how to improve the accuracy of demand and supply results and better measuring the spatial fairness of elderly service is significant to realize the optimal allocation of rural elderly service.Based on the above,this study pays attention to the refined needs of the elderly population,and focuses on the spatial equity of the rural elderly facilities,to make up for the short boards of the basic public services in the countryside and realize the all-round rural revitalization.This study takes Huanxian County in the hilly loess area of Longdong,China as an example and explores the spatial equity of rural elderly services by using the Urban Spatial Network Analysis(UNA)to measure the accessible quantity and supply capacity of elderly services.The results found that there were 553 rural eldercare service facilities in Huanxian County,including 285 eldercare facilities and 268 medical and health facilities,and the spatial distribution is characterized by a southward shift in the east and uneven regional distribution.Overall,the supply capacity of rural pension services was generally good,with the township center as the gathering point and spreading out in a faceted manner,with nearby townships forming a contiguous area;however,there were strong contrasts and obvious differences in the strength of supply capacity.However,the spatial equity of rural eldercare service was poor.In 42.05%of the eld-erly population grid cells,eldercare service spatial equity was extremely low.The spatial distribution also presented a northern preference over the southern,a western preference over the eastern,and a concentration along the highway.The study explored the realization of spatial equity in the optimal allocation of rural elderly services based on paying attention to the refined needs of the rural elderly pop-ulation,a vulnerable group,to provide a reference for solving the shortcomings of basic public services in rural areas.The fair allocation of rural elderly services demands that the spatial optimization of facility layout be organically coordinated with policy,management,and post-maintenance,and all elements in the rural territorial system be fully mobilized to achieve the basic guarantee of China’s rural elderly problems.展开更多
Precipitation isotopes(δ^(18)O and δ^(2)H)are closely related to meteorological conditions for precipitation generation and the initial state of water vapor source areas,and are essential to the study of the regiona...Precipitation isotopes(δ^(18)O and δ^(2)H)are closely related to meteorological conditions for precipitation generation and the initial state of water vapor source areas,and are essential to the study of the regional hydrological cycle.The deuterium excess(d-excess)indicates deviation in isotope fractionation during evaporation and can trace water vapor sources.This study analyzed 443 precipitation samples collected from the Gannan Plateau,China in 2022 to assess precipitation isotope variations and their driving factors.Water vapor sources were evaluated using the Hybrid Single-Particle Lagrangian Integrated Trajectory(HYSPLIT),Concentration Weighted Trajectory(CWT),and Potential Source Contribution Factor(PSCF)models.Results showed that precipitation isotope values showed significant spatial and temporal variations on the Gannan Plateau.Temporally,precipitation isotope values peaked in June(when evaporation dominated)and minimized in March(depletion effect of air masses in the westerly wind belt).Spatially,the isotope values showed a distribution pattern of"high in the east and low in the west",which was mainly regulated by the differences in altitude and local meteorological conditions.Compared with the global meteoric water line(GMWL)with equation of δ^(2)H=8.00δ^(18)O+10.00,the slope and intercept of local meteoric water line(LMWL)for precipitation on the Gannan Plateau were smaller(7.49 and 7.63,respectively),reflecting the existence of a stronger secondary evaporation effect under the clouds in the region.The sources of water vapor on the Gannan Plateau showed significant seasonality and spatial heterogeneity.Specifically,the westerly belt and monsoon were the main water vapor transport paths at each sampling point,with Central Asian continental water vapor dominating in spring(53.49%),Indian Ocean water vapor dominating in summer(52.53%),Atlantic Ocean water vapor dominating in autumn(46.74%),and Atlantic Ocean and Mediterranean Sea water vapor dominating in winter(42.30%and 33.68%,respectively).Changes in the intensity of convective activity and Outgoing Longwave Radiation(OLR)affected the enrichment of isotopic values,which exhibited the same change trends as δ^(18)O.During the precipitation process,the δ^(18)O value first decreased and then increased.During the initial and final stages of precipitation process,precipitation was mainly influenced by continental air masses,while during the middle stage,it was controlled by marine air masses.The systematic research on precipitation isotopes and water vapor sources is important for climate change research and extreme precipitation prediction on the Gannan Plateau and other similar areas.展开更多
Honey,a natural substance,has long been valued for its dual role in both food and medicine in diverse cultural traditions,particularly in traditional Chinese medicine(TCM).It is rich in sugars,amino acids,enzymes,poly...Honey,a natural substance,has long been valued for its dual role in both food and medicine in diverse cultural traditions,particularly in traditional Chinese medicine(TCM).It is rich in sugars,amino acids,enzymes,polyphenols,and flavonoids that contribute to its antimicrobial,antioxidant,and immuno-modulatory properties.Additionally,honey is effective in managing some conditions,such as antibiotic-resistant infections,inflammation,and oxidative stress-related diseases.This review explores the extensive health benefits of honey,emphasizing the homology between food and medicine,as proposed by TCM philosophy.Further,this review explores the traditional applications of honey in respiratory health,wound healing,and gastrointestinal support,along with modern scientific validation of these uses.Moreover,the role of honey as a dietary supplement,functional food,and preservative in culinary practices is examined.Overall,this review highlights the synergy between ancient wisdom and contemporary science,advocating for the continued exploration of the role of honey in health,nutrition,and medicine.展开更多
The efficient recovery of silver(Ag)from retired photovoltaic(PV)panels is crucial for resource sustainability and envi-ronmental protection.This study developed an environmentally friendly leaching method using ammon...The efficient recovery of silver(Ag)from retired photovoltaic(PV)panels is crucial for resource sustainability and envi-ronmental protection.This study developed an environmentally friendly leaching method using ammonia(NH_(3)·H_(2)O)and hydrogen peroxide(H_(2)O_(2)),achieving the selective dissolution of Ag from retired crystalline silicon solar panels.Meanwhile,nonprecious metals such as aluminum(Al)and lead(Pb),which are commonly found in PV cells,were barely dissolved,dem-onstrating the excellent selectivity of this method for Ag.Light irradiation significantly improved the dissolution efficiency of Ag and reduced the amount of the reagent used.Ag dissolution occurred owing to a dual-pathway synergistic effect,which stemmed from the direct oxidation of Ag by H_(2)O_(2).The strongly oxidizing hydroxyl radicals generated by photocatalysis accelerated the oxidation and dissolution of Ag.In addition,NH 3·H_(2)O effectively promoted the dissolution and stabilization of oxidation products by forming soluble Ag–NH3·H2O complexes([Ag(NH3)2]+).This article reports an efficient,selective,and environmentally friendly strategy of Ag recovery and elucidates the radical-mediated dissolution mechanism under light-driven conditions,offering a feasible way for sustainably recovering valuable metals from retired PV panels.展开更多
Stilbenes,a natural plant phytoalexin,are involved in the plant's response to various biotic and abiotic stresses in its environment.STILBENE SYNTHASE(STS)is the key enzyme regulating resveratrol synthesis in grap...Stilbenes,a natural plant phytoalexin,are involved in the plant's response to various biotic and abiotic stresses in its environment.STILBENE SYNTHASE(STS)is the key enzyme regulating resveratrol synthesis in grapevine.However,the regulatory mechanism of STS gene expression remains unclear.In this study,we reported a NAC transcription factor,VqNAC17,in Vitis quinquangularis,which can improve plant resistance to salt stress,drought stress,and Pseudomonas syringae pv.Tomato DC3000(Pst DC3000)in transgenic Arabidopsis thaliana.Additionally,the interaction between the transcription factors VqNAC17 and VqMYB15 was confrmed using yeast two-hybrid and BiFC.In transgenic A.thaliana,VqNAC17 participates in plant immunity through interaction with VqMYB15 to affect the stilbene synthesis.Furthermore,the experimental results of the yeast one-hybrid assay and LUC transient expression assay found that VqNAC17 can also bind to the promoter of VqMYB15.These results indicate that VqNAC17 is a key regulator that can promote the expression of STS by interacting with VqMYB15.展开更多
The Western Himalaya,often termed the“Water Tower of Asia,”is experiencing critical hydrological changes due to global warming.This review synthesizes current scientific knowledge on climate-driven alterations in th...The Western Himalaya,often termed the“Water Tower of Asia,”is experiencing critical hydrological changes due to global warming.This review synthesizes current scientific knowledge on climate-driven alterations in the region’s water cycle,assessing impacts on ecosystems,agriculture,energy security,and local livelihoods.We conducted a systematic literature review of peer-reviewed studies(2000-2024)from Scopus,Web of Science,and regional databases,supplemented by case studies and observational/modeling data.Key themes include cryospheric loss,shifting precipitation,river flow variability,and hydrological extremes.Key findings indicate that(1)temperature increases(0.2-0.5°C/decade)have accelerated glacier retreat(up to 20-30%mass loss in some basins)and reduced snow cover(5-15%decline since 2000);(2)altered precipitation patterns have increased rainfall dominance,elevating flood risks while reducing groundwater recharge in arid zones;and(3)river discharge shows declining dry-season flows but higher peak flows,threatening water security for over 200 million downstream inhabitants.These findings underscore the urgent need for integrated,cross-scale strategies combining scientific innovation,indigenous knowledge,and adaptive policies to enhance resilience.We highlight critical gaps in high-altitude monitoring and call for transboundary cooperation to mitigate escalating climate risks.This systematic review uniquely contrasts Western Himalayan hydrology with that of the Central and Eastern regions and benchmarks policy gaps,offering a roadmap for climate-resilient water governance.展开更多
Due to irrational human activities and extreme climate,the Qinghai-Xizang Plateau,China,faces a serious threat of desertification.Desertification has a detrimental effect on the ecological environment and socioeconomi...Due to irrational human activities and extreme climate,the Qinghai-Xizang Plateau,China,faces a serious threat of desertification.Desertification has a detrimental effect on the ecological environment and socioeconomic development.In this study,the desertification sensitivity index(DSI)model was established by integrating the spatial distance model and environmentally sensitive area index evaluation method,and then the model was used to quantitatively analyze the spatial and temporal characteristics of desertification sensitivity of the Qinghai-Xizang Plateau from 1990 to 2020.The results revealed that:(1)a general increasing tendency from southeast to northwest was identified in the spatial distribution of desertification sensitivity.The low-sensitivity areas were mostly concentrated in the Hengduan and Nyaingqêntanglha mountains and surrounding forest and meadow areas.The high-sensitivity areas were located mainly in the Kunlun and Altun mountains and surrounding decertified areas.The center of gravity of all types of desertification-sensitive areas moved to the northwest,and the desertification sensitivity showed a decreasing trend as a whole;(2)the area of highly sensitive desertification areas decreased by 8.37%,with extreme sensitivity being the largest change among the sensitivity types.The desertification sensitivity transfer was characterized by a greater shift to lower sensitivity levels(24.56%)than to higher levels(2.03%),which demonstrated a declining trend;(3)since 1990,the change in desertification sensitivity has been dominated by the stabilizing type Ⅰ(29.30%),with the area of continuously increasing desertification sensitivity accounting for only 1.10%,indicating that the management of desertification has achieved positive results in recent years;and(4)natural factors have had a more significant impact on desertification sensitivity on the Xizang Plateau,whereas socioeconomic factors affected only localized areas.The main factors influencing desertification sensitivity were vegetation drought tolerance and aridity index.Studying spatiotemporal variations in desertification sensitivity and its influencing factors can provide a scientific foundation for developing strategies to control desertification on the Qinghai-Xizang Plateau.Dividing different desertification-sensitive areas on the basis of these patterns of change can facilitate the formulation of more targeted management and protection measures,contributing to ecological construction and sustainable economic development in the area.展开更多
Intraspecific genetic variance and gene flow can support the adaptive evolution of species challenged by climate shifts or novel environmental conditions.Less well understood is how genome organization and gene flow i...Intraspecific genetic variance and gene flow can support the adaptive evolution of species challenged by climate shifts or novel environmental conditions.Less well understood is how genome organization and gene flow interact in closely related species during evolutionary divergence and differentiation.Here we conducted genomic footprint analyses to determine how three species of Pterocarya(P.stenoptera,P.hupehensis,and P.macroptera),which are sympatric but occupy different elevational niches,adapted to the heterogeneous environment of the Qinling-Daba Mountains,China.We identified candidate genes for environmental adaptation(i.e.,PIEZO1,WRKY39,VDAC3,CBL1,and RAF),and also identified regions of gene introgression between P.hupehensis and P.macroptera that show lower genetic load and higher genetic diversity than the rest of their genomes.The same introgressed regions are notably situated in areas of minimal genetic divergence yet they are characterized by elevated recombination rates.We also identified candidate genes within these introgressed regions related to environmental adaptation(TPLC2,CYCH;1,LUH,bHLH112,GLX1,TLP-3,and ABC1).Our findings have thus clarified the important role of gene flow in ecological adaptation and revealed genomic signatures of past introgression.Together,these findings provide a stronger theoretical basis for understanding the ecological adaptation and conservation of Quaternary relict woody plants in East Asia.展开更多
Metal(oxide)-zeolite bifunctional catalysts have been the subject of considerable attention from researchers in both academic and industry,due to their superior activity and stability in various heterogeneous catalyti...Metal(oxide)-zeolite bifunctional catalysts have been the subject of considerable attention from researchers in both academic and industry,due to their superior activity and stability in various heterogeneous catalytic processes[1–3].Based on the different metal loading sites,these bifunctional catalysts can be categorized as follows:(a)metal species loaded on the outer surface of zeolite crystals,(b)metal species encapsulated within the channels or cavities of zeolites,and(c)metal species incorporated into the zeolite framework(Fig.1).Metal species in type(b)and(c)samples are stabilized by the zeolite frameworks,resulting in excellent thermal and hydrothermal stability during catalytic reactions,especially under harsh conditions,as well as unique shape-selectivity.However,the complex synthesis procedures make large-scale preparation of these catalysts impractical.In contrast,a type(a)sample can be achieved via the simple impregnation;nevertheless,migration of metal species and their aggregation into larger particles often occur during the calcination and reduction processes.展开更多
Rural resilience,a core capability for addressing systemic risks and enabling sustainable development,is increasingly vital to promoting urban-rural integrated development and rural revitalization strategies.However,c...Rural resilience,a core capability for addressing systemic risks and enabling sustainable development,is increasingly vital to promoting urban-rural integrated development and rural revitalization strategies.However,current research lacks exploration of the collaborative mechanisms between rural economic resilience(RER)and rural social resilience(RSR)in ecologically vulnerable areas.Based on the practical context of rural sustainable development in such regions,this study investigates the interaction between RER and RSR from a resilience coordination perspective.In this paper,a rural resilience evaluation framework for collaborative development of economic and social resilience was established.By employing the coupling coordination degree model,obstacle degree model,and equilibrium entropy model,this paper examines the synergies,constraints,and potential of rural resilience subsystems in Jinchang City,Gansu Province,China,in 2020.The results reveal that:1)RER contributes to RSR by stabilizing the economy,enhancing community adaptability,and driving modernization.In turn,RSR strengthens RER by mitigating instability,building social capital,and fostering confidence—together forming a mutually reinforcing coupling mechanism.2)The rural economic and social resilience level in Jinchang City remains generally low with spatially clustered patterns,while the coupling coordination degree is at an intermediate level overall,with 62.59%of villages exhibiting unbalanced development between rural economic and social resilience.3)RER and RSR demonstrate synergistic degradation in ecologically vulnerable areas,where low-level rural economic and social resilience induce integrated systemic deterioration.4)Considering the unbalanced development of rural economic and social resilience in ecologically fragile areas,differentiated coordination pathways are proposed for three village typologies:RER-lagging villages,RSR-lagging villages,and villages where RER and RSR develop synchronously but lack effective coordination.These findings offer spatial governance strategies and practical guidance for enhancing rural resilience and advancing sustainable development in ecologically vulnerable regions.展开更多
Background:Small ubiquitin-like modifier(SUMO)-specific proteases(SENPs)cleave the isopeptidic bond between SUMO1/2/3 and protein substrates,thus regulating the structure,activity,and lifetime of a variety of proteins...Background:Small ubiquitin-like modifier(SUMO)-specific proteases(SENPs)cleave the isopeptidic bond between SUMO1/2/3 and protein substrates,thus regulating the structure,activity,and lifetime of a variety of proteins.Recently,accumulating evidence has suggested that SENPs play a role in the initiation and progression of human cancers.Nevertheless,the potential role of the SENP family of proteins in liver cancer has yet to be fully elucidated.Methods:This study conducted a comprehensive bioinformatics analysis of the SENP family in liver cancer,including differential expression profiling,survival analysis,mutation and copy number variations(CNVs)assessment,immune infiltration and drug sensitivity correlation,functional enrichment analyses using data from The Cancer Genome Atlas(TCGA),Clinical Proteomic Tumor Analysis Consortium(CPTAC),LinkedOmics,and other public databases.Furthermore,we performed in vitro experiments using Huh-7 and Hep-3B cell lines to investigate the functional roles of SENP1 and SENP3 in hepatocellular carcinoma cell proliferation,colony formation,and migration.Results:Our results indicated that SENP1,3,and 7 were significantly overexpressed in liver hepatocellular carcinoma(LIHC).Elevated expressions of SENP1,3,and 7 are positively correlated with poor overall survival(OS)in LIHC patients.In addition,SENP1,3,and 7 expressions are related to immune infiltration and drug sensitivity.SENP1,3,and 7 co-expressed genes were enriched in mitochondrial function,ribosomal translation,and cell cycle control.Conclusion:SENP1,3,and 7 are prognostic biomarkers and potential therapeutic targets for LIHC.Knockdown of SENP1 and SENP3 inhibited the proliferation,clonogenicity,and migration of hepatocellular carcinoma cells.展开更多
Under current climate warming, the growth resilience of plantation forests after extreme droughts has garnered increasing attention. Platycladus orientalis Linn. is an evergreen tree species commonly used for afforest...Under current climate warming, the growth resilience of plantation forests after extreme droughts has garnered increasing attention. Platycladus orientalis Linn. is an evergreen tree species commonly used for afforestation, and the stability of P. orientalis plantation forests in the Loess Hilly region directly affects the ecological and environmental security of the entire Loess Plateau of China.However, systematic analyses of the growth resilience of P. orientalis plantation forests after extreme droughts along precipitation gradients remain scarce. In this study, we collected tree ring samples of P.orientalis along a precipitation gradient(255, 400, and 517 mm) from 2021 to 2023 and used dendroecological methods to explore the growth resilience of P. orientalis to drought stress on the Loess Plateau. Our findings revealed that the growth resilience of P. orientalis increased with increasing precipitation, enabling the trees to recover to the pre-drought growth levels. In regions with low precipitation(255 mm), the plantation forests were more sensitive to extreme droughts, struggling to recover to previous growth levels, necessitating conditional artificial irrigation. In regions with medium precipitation(400 mm), the growth of P. orientalis was significantly limited by drought stress and exhibited some recovery ability after extreme droughts, therefore warranting management through rainwater harvesting and conservation measures. Conversely, in regions with high precipitation(517 mm), the impacts of extreme droughts on P. orientalis plantation forests were relatively minor. This study underscored the need for targeted strategies tailored to different precipitation conditions rather than a "one-size-fits-all" approach to utilize precipitation resources effectively and maximize the ecological benefits of plantation forests. The findings will help maintain the stability of plantation forests and improve their ecosystem service functions in arid and semi-arid areas.展开更多
The survival and mortality of conifer trees in response to climate change,particularly drought stress,have received considerable attention.However,it is crucial to explore the growth dynamics of the same conifer speci...The survival and mortality of conifer trees in response to climate change,particularly drought stress,have received considerable attention.However,it is crucial to explore the growth dynamics of the same conifer species in response to climate change in different climatic habitats.In this study,we aimed to quantify variations in the radial growth processes of conifer species,analyze their resilience during drought periods under different climatic habitats,and assess the impact of climate adaptation on conifer growth.We focused on two conifer species,Picea crassifolia(spruce)and Pinus tabuliformis(pine),which are distributed in both a humid habitat and a dry habitat in the northeastern Tibetan Plateau.Growth and resilience dynamics were identified across both climatic habitats and the contributions of temperature and moisture to the growth of the two species were simulated under drought stress using the VS-oscilloscope model.Spruce growth exhibited significant variability between climatic habitats.Specifically,the spruce growth rate declined in response to drought in the dry habitat(-0.91 cm^(2)per decade,p<0.01).In contrast,pine growth remained relatively stable(humid habitat:-0.03 cm^(2)per decade;dry habitat:0.25 cm^(2)per decade,p>0.01),although it still responded to stress during the growing season(p<0.05).Furthermore,spruce displayed reduced resistance during stress in dry habitats(-30.11%),while pine exhibited an enhanced recovery of growth rates to ensure survival(+39.62%).The climate adaptation strategies of the species were linked to the contribution of temperature and moisture to their growth rates.Moisture is critical for the growth recovery of both conifers in dry habitats when temperature-associated growth displays a‘bimodal’pattern during the growing season.These findings have significant ecological implications for understanding conifer forest processes in the context of global climate change.展开更多
基金supported by the National Natural Science Foundation of China(Grant No.42301235)Gansu Province Key Research and Development Program Project(Grant No.22YF7FA124)+1 种基金Lanzhou Youth Science and Technology Talent Innovation Program(Grant No.2023-QN-54)Northwest Normal University Young Teachers’Research Ability Enhancement Program Backbone Project(Grant No.NWNU-LKQN2023-11)。
文摘Meeting China's burgeoning food demand while safeguarding the resources and environmental long-term development is a critical challenge for the sustainable food systems of this century.China's accelerated food imports have far-reaching implications for global resource allocation and environmental development.Hence,detailed information regarding China's food trade resource-environmental impacts is imperative for the design of effective policies that promote environmental mitigation and resource conservation.This study estimated the spatial transfers of virtual water trade(VWT),virtual land trade(VLT),and virtual GHG emission trade(VGT)embodied in China's food trade.Findings indicate that the VWT,VLT,and VGT transfers embodied in China's food trade increased by 10.4%,9.8%,and 15.2%annually.It is more important to mention that virtual water import(VWI)and virtual land import(VLI)saved 119.5×10~9m^(3)of global water resources and 29.5 Mha of land resources,respectively,but virtual GHG emission import(VGI)increased global 13 Mt CO_(2)-eq GHG emissions.The divergent impacts of China's food import on global food sustainability stem from variations in virtual water content,yields and emission intensities.Moreover,significant differences in sustainability scores were found among the top 15 importing countries,indicating that China's food trade contributes to the deepening of global food system sustainability.This study highlights the need for a multifaceted approach that considers the various environmental impacts of food trade.China is therefore encouraged to fully integrate the benefits of resource and environmental conservation into its sustainable food trade strategy,restructuring the food system to ensure the long-term nourishment of its large population.
基金supported by the Natural Science Foundation of Beijing Municipality(6252026)the Youth Innovation Program of CAAS(Y2024QC11)the Agricultural Science and Technology Innovation Program under Grant(CAAS-ASTIP-2024-IAR).
文摘The monofloral honey derived from Bauhinia championii(Benth.)Benth.(MH-Bc)possesses significant nutritional and bioactive value,making it highly suitable for commercial exploitation.However,the poorly defined characteristics and unknown composition have hindered MH-Bc product development.In this study,we employed a combination of untargeted and targeted mass spectrometry analyses to characterize MH-Bc honey.As a result,4,7,8-trimethoxydibenzo[b,d]furan-3-ol(TDBF)was identified as a robust chemical marker for distinguishing MH-Bc from other types of honey.This specific marker was detected in both MH-Bc and the Bc plant but was absent in other honey varieties.Furthermore,a targeted mass spectrometry quantitative method was developed and validated to accurately determine the content of TDBF in honey samples.Overall,the presence of TDBF serves as a discerning indicator for future commercial MH-Bc products.
基金the financial support by the Beijing Natural Science Foundation (No.Z230018)the Strategic Priority Research Program of the Chinese Academy of Sciences (No.XDB0520102)CAS Project for Young Scientists in Basic Research (No.YSBR-102)。
文摘In the field of organic solar cells(OSCs),side-chain engineering is a key strategy for developing high-performance non-fullerene small molecule acceptors(SMAs),which could adjust the material solubility and modulate the intermolecular stacking properties,profoundly impacting the film morphology and thus acting on the final power conversion efficiency(PCE) of the materials.In this study,two asymmetric acceptor molecules,Qx-Ph Br-BO and Qx-Ph Br-X,were synthesized by migrating the branching site of the outer side chain from the β-site to the γ-site.The branching site located at the γ-site could reduce the steric-hindrance effect and enhance the molecular aggregation behavior,giving rise to redshifted absorption and tight π-π stacking.Morphology analysis shows that the Qx-Ph Br-X-based devices have smoother surfaces and a phase-separated structure,which is more favorable for charge transport and extraction.The Qx-Ph Br-X-based devices exhibit balanced hole-electron mobility,efficient exciton dissociation,and low charge recombination.As a result,Qx-Ph Br-X with γ-site branching exhibits superior photovoltaic performance with a PCE of 17.16 %,which is significantly higher than that of Qx-Ph Br-BO at 16.28 %.These results highlight the importance of side-chain modifications for optimizing OSC efficiency and provide an important reference for precise tuning of side-chain structures in future molecular design.
基金grants from National Key R and D Program for Crop Breeding(2016YFD0100306)National Natural Science Foundation of China(No.31401431)+2 种基金the Shaanxi Science and Technology Innovation Team(2019TD-012)the Public health specialty in the Department of Traditional Chinese Medicine(Grants no.2017-66 and 2018-43)the Open Foundation of the Key Laboratory of Resource Biology and Biotechnology in Western China(Ministry of Education)(Grants no.ZSK2017007 and ZSK2019008)。
文摘Gene flow patterns and the genetic structure of domesticated crops like cotton are not well understood.Furthermore,marker-assisted breeding of cotton has lagged far behind that of other major crops because the loci associated with cotton traits such as fiber yield and quality have scarcely been identified.In this study,we used 19 microsatellites to first determine the population genetic structure and patterns of gene flow of superior germplasm resources in upland cotton.We then used association analysis to identify which markers were associated with 15 agronomic traits(including ten yield and five fiber quality traits).The results showed that the upland cotton accessions have low levels of genetic diversity(polymorphism information content=0.427),although extensive gene flow occurred among different ecological and geographic regions.Bayesian clustering analysis indicated that the cotton resources used in this study did not belong to obvious geographic populations,which may be the consequence of a single source of domestication followed by frequent genetic introgression mediated by human transference.A total of 82 maker-trait associations were examined in association analysis and the related ratios for phenotypic variations ranged from 3.04% to 47.14%.Interestingly,nine SSR markers were detected in more than one environmental condition.In addition,14 SSR markers were co-associated with two or more different traits.It was noteworthy that NAU4860 and NAU5077 markers detected at least in two environments were simultaneously associated with three fiber quality traits(uniformity index,specific breaking strength and micronaire value).In conclusion,these findings provide new insights into the population structure and genetic exchange pattern of cultivated cotton accessions.The quantitative trait loci of domesticated cotton identified will also be very useful for improvement of yield and fiber quality of cotton in molecular breeding programs.
基金Foundation items： This work was supported by grants from the National Natural Science Foundation of China （31160422, 30960084） the China Postdoctoral Science Foundation （2013M542379）, the Program for New Century Excellent Talents in University （NCET-12- 1079）, and the Key Subject of Wildlife Conservation and Utilization in Yunnan Province. Acknowledgements： Special thanks to Prof. R.-J. ZOU at Kunming Institute of Zoology, Chinese Academy of Sciences for support Mr. Y.-Z. LU （animal keeper） for his assistance during data-collection and to three anonymous reviewers for valuable suggestions.
文摘Different types of dominance hierarchies reflect different social relationships in primates. In this study, we clarified the hierarchy and social relationships in a one-male unit of captive Rhinopithecus bieti observed between August 1998 and March 1999. Mean frequency of agonistic behaviour among adult females was 0.13 interactions per hour. Adult females exhibited a linear hierarchy with a reversal of 10.9%, indicating an unstable relationship; therefore, R. bieti appears to be a relaxed/tolerant species. The lack of a relationship between the agonistic ratio of the adult male towards adult females and their ranks indicated that males did not show increased aggression towards low-ranking females. Differentiated female affiliative relationships were loosely formed in terms of the male, and to some extent influenced by female estrus, implying that relationships between the male and females is influenced by estrus and not rank alone. A positive correlation between the agonistic ratio of adult females and their ranks showed that the degree to which one female negatively impacted others decreased with reduction in rank. Similarly, a positive correlation between the agonistic ratio of females and differences in rank suggests that a female had fewer negative effects on closely ranked individuals than distantly ranked ones. These data indicate that rank may influence relationships between females. A steeper slope of regression between the agonistic ratio and inter-female rank differences indicated that the extent of the power difference in high-ranking females exerting negative effects on low-ranking ones was larger during the mating season than the birth season, suggesting that rank may influence the mating success of females.
基金Under the auspices of the National Natural Science Foundation of China(No.42271222)Natural Science Foundation of Gansu Province(No.22JR5RA130,22JR5RA143)。
文摘Safeguarding the elderly population in the countryside is an inherent requirement for alleviating social conflicts in rural areas and effectively carrying out China’s Rural Revitalization.The existing spatial mismatch between rural elderly service facilities and pop-ulation distribution in China aggravates the imbalance of facility resource space,how to improve the accuracy of demand and supply results and better measuring the spatial fairness of elderly service is significant to realize the optimal allocation of rural elderly service.Based on the above,this study pays attention to the refined needs of the elderly population,and focuses on the spatial equity of the rural elderly facilities,to make up for the short boards of the basic public services in the countryside and realize the all-round rural revitalization.This study takes Huanxian County in the hilly loess area of Longdong,China as an example and explores the spatial equity of rural elderly services by using the Urban Spatial Network Analysis(UNA)to measure the accessible quantity and supply capacity of elderly services.The results found that there were 553 rural eldercare service facilities in Huanxian County,including 285 eldercare facilities and 268 medical and health facilities,and the spatial distribution is characterized by a southward shift in the east and uneven regional distribution.Overall,the supply capacity of rural pension services was generally good,with the township center as the gathering point and spreading out in a faceted manner,with nearby townships forming a contiguous area;however,there were strong contrasts and obvious differences in the strength of supply capacity.However,the spatial equity of rural eldercare service was poor.In 42.05%of the eld-erly population grid cells,eldercare service spatial equity was extremely low.The spatial distribution also presented a northern preference over the southern,a western preference over the eastern,and a concentration along the highway.The study explored the realization of spatial equity in the optimal allocation of rural elderly services based on paying attention to the refined needs of the rural elderly pop-ulation,a vulnerable group,to provide a reference for solving the shortcomings of basic public services in rural areas.The fair allocation of rural elderly services demands that the spatial optimization of facility layout be organically coordinated with policy,management,and post-maintenance,and all elements in the rural territorial system be fully mobilized to achieve the basic guarantee of China’s rural elderly problems.
基金supported by the National Natural Science Foundation of China(42161007)the Innovation Foundation of Higher Education Institutions of Gansu Province(2021B-081)the Foundation for Distinguished Young Scholars of Gansu Province(20JR10RA112).
文摘Precipitation isotopes(δ^(18)O and δ^(2)H)are closely related to meteorological conditions for precipitation generation and the initial state of water vapor source areas,and are essential to the study of the regional hydrological cycle.The deuterium excess(d-excess)indicates deviation in isotope fractionation during evaporation and can trace water vapor sources.This study analyzed 443 precipitation samples collected from the Gannan Plateau,China in 2022 to assess precipitation isotope variations and their driving factors.Water vapor sources were evaluated using the Hybrid Single-Particle Lagrangian Integrated Trajectory(HYSPLIT),Concentration Weighted Trajectory(CWT),and Potential Source Contribution Factor(PSCF)models.Results showed that precipitation isotope values showed significant spatial and temporal variations on the Gannan Plateau.Temporally,precipitation isotope values peaked in June(when evaporation dominated)and minimized in March(depletion effect of air masses in the westerly wind belt).Spatially,the isotope values showed a distribution pattern of"high in the east and low in the west",which was mainly regulated by the differences in altitude and local meteorological conditions.Compared with the global meteoric water line(GMWL)with equation of δ^(2)H=8.00δ^(18)O+10.00,the slope and intercept of local meteoric water line(LMWL)for precipitation on the Gannan Plateau were smaller(7.49 and 7.63,respectively),reflecting the existence of a stronger secondary evaporation effect under the clouds in the region.The sources of water vapor on the Gannan Plateau showed significant seasonality and spatial heterogeneity.Specifically,the westerly belt and monsoon were the main water vapor transport paths at each sampling point,with Central Asian continental water vapor dominating in spring(53.49%),Indian Ocean water vapor dominating in summer(52.53%),Atlantic Ocean water vapor dominating in autumn(46.74%),and Atlantic Ocean and Mediterranean Sea water vapor dominating in winter(42.30%and 33.68%,respectively).Changes in the intensity of convective activity and Outgoing Longwave Radiation(OLR)affected the enrichment of isotopic values,which exhibited the same change trends as δ^(18)O.During the precipitation process,the δ^(18)O value first decreased and then increased.During the initial and final stages of precipitation process,precipitation was mainly influenced by continental air masses,while during the middle stage,it was controlled by marine air masses.The systematic research on precipitation isotopes and water vapor sources is important for climate change research and extreme precipitation prediction on the Gannan Plateau and other similar areas.
基金supported by the National Natural Science Foundation of China(32322079)Beijing Nova Program(20220484101)Talented Young Scientist Program,Ministry of Science and Technology of the People's Republic of China,and China Postdoctoral Science Foundation(2024M753576).
文摘Honey,a natural substance,has long been valued for its dual role in both food and medicine in diverse cultural traditions,particularly in traditional Chinese medicine(TCM).It is rich in sugars,amino acids,enzymes,polyphenols,and flavonoids that contribute to its antimicrobial,antioxidant,and immuno-modulatory properties.Additionally,honey is effective in managing some conditions,such as antibiotic-resistant infections,inflammation,and oxidative stress-related diseases.This review explores the extensive health benefits of honey,emphasizing the homology between food and medicine,as proposed by TCM philosophy.Further,this review explores the traditional applications of honey in respiratory health,wound healing,and gastrointestinal support,along with modern scientific validation of these uses.Moreover,the role of honey as a dietary supplement,functional food,and preservative in culinary practices is examined.Overall,this review highlights the synergy between ancient wisdom and contemporary science,advocating for the continued exploration of the role of honey in health,nutrition,and medicine.
基金supported by the National Science Foundation of China(Nos.22525606,22176128,22236005,22406131,22506126)the Innovation Program of Shanghai Municipal Education Commission(No.2023ZKZD50)+13 种基金Shanghai Leading Talent Program of Eastern Talent Plan(No.LJ2023002)Shanghai Government(Nos.22dz1205400,23520711100)Chinese Education Ministry Key Laboratory and International Joint Laboratory on Resource ChemistryShanghai Eastern Scholar ProgramThe authors also thank Fellowship of China National Postdoctoral Program for Innovative Talents(No.BX20240229)the China Postdoctoral Science(No.2024M762100)the Foundation the Shanghai Science and Technology Commission Project(No.24ZR1455700)Shanghai Post-doctoral Excellence Pro-gram(No.2024787)the Chenguang Program of Shanghai Education Development Foundation and Shanghai Municipal Education Com-mission(No.24CGA49)the“111 Innovation and Talent Recruitment Base on Photochemical and Energy Materials”(No.D18020)Yunnan University Collaborative Innovation Center(Qujing Green Photovoltaic Industry Collaborative Innovation Center)Technology Talent and Platform Plan Project of Yunnan Provincial Department of Science and Technology(No.202305AF150088)Shanghai Engineering Research Center of Green Energy Chemical Engineering(No.18DZ2254200)Shanghai Frontiers Science Center of Biomimetic Catalysis.
文摘The efficient recovery of silver(Ag)from retired photovoltaic(PV)panels is crucial for resource sustainability and envi-ronmental protection.This study developed an environmentally friendly leaching method using ammonia(NH_(3)·H_(2)O)and hydrogen peroxide(H_(2)O_(2)),achieving the selective dissolution of Ag from retired crystalline silicon solar panels.Meanwhile,nonprecious metals such as aluminum(Al)and lead(Pb),which are commonly found in PV cells,were barely dissolved,dem-onstrating the excellent selectivity of this method for Ag.Light irradiation significantly improved the dissolution efficiency of Ag and reduced the amount of the reagent used.Ag dissolution occurred owing to a dual-pathway synergistic effect,which stemmed from the direct oxidation of Ag by H_(2)O_(2).The strongly oxidizing hydroxyl radicals generated by photocatalysis accelerated the oxidation and dissolution of Ag.In addition,NH 3·H_(2)O effectively promoted the dissolution and stabilization of oxidation products by forming soluble Ag–NH3·H2O complexes([Ag(NH3)2]+).This article reports an efficient,selective,and environmentally friendly strategy of Ag recovery and elucidates the radical-mediated dissolution mechanism under light-driven conditions,offering a feasible way for sustainably recovering valuable metals from retired PV panels.
基金supported by the National Natural Science Foundation of China(31970348 and 31600256)the International Scientifc and Technological Cooperation Projects of Shaanxi Province,China(2022KW-45)+1 种基金the Young Academic Talent Support Program of Northwest Universitythe Xi’an Agriculture Technology Research General Project,China(24NYGG0088)。
文摘Stilbenes,a natural plant phytoalexin,are involved in the plant's response to various biotic and abiotic stresses in its environment.STILBENE SYNTHASE(STS)is the key enzyme regulating resveratrol synthesis in grapevine.However,the regulatory mechanism of STS gene expression remains unclear.In this study,we reported a NAC transcription factor,VqNAC17,in Vitis quinquangularis,which can improve plant resistance to salt stress,drought stress,and Pseudomonas syringae pv.Tomato DC3000(Pst DC3000)in transgenic Arabidopsis thaliana.Additionally,the interaction between the transcription factors VqNAC17 and VqMYB15 was confrmed using yeast two-hybrid and BiFC.In transgenic A.thaliana,VqNAC17 participates in plant immunity through interaction with VqMYB15 to affect the stilbene synthesis.Furthermore,the experimental results of the yeast one-hybrid assay and LUC transient expression assay found that VqNAC17 can also bind to the promoter of VqMYB15.These results indicate that VqNAC17 is a key regulator that can promote the expression of STS by interacting with VqMYB15.
文摘The Western Himalaya,often termed the“Water Tower of Asia,”is experiencing critical hydrological changes due to global warming.This review synthesizes current scientific knowledge on climate-driven alterations in the region’s water cycle,assessing impacts on ecosystems,agriculture,energy security,and local livelihoods.We conducted a systematic literature review of peer-reviewed studies(2000-2024)from Scopus,Web of Science,and regional databases,supplemented by case studies and observational/modeling data.Key themes include cryospheric loss,shifting precipitation,river flow variability,and hydrological extremes.Key findings indicate that(1)temperature increases(0.2-0.5°C/decade)have accelerated glacier retreat(up to 20-30%mass loss in some basins)and reduced snow cover(5-15%decline since 2000);(2)altered precipitation patterns have increased rainfall dominance,elevating flood risks while reducing groundwater recharge in arid zones;and(3)river discharge shows declining dry-season flows but higher peak flows,threatening water security for over 200 million downstream inhabitants.These findings underscore the urgent need for integrated,cross-scale strategies combining scientific innovation,indigenous knowledge,and adaptive policies to enhance resilience.We highlight critical gaps in high-altitude monitoring and call for transboundary cooperation to mitigate escalating climate risks.This systematic review uniquely contrasts Western Himalayan hydrology with that of the Central and Eastern regions and benchmarks policy gaps,offering a roadmap for climate-resilient water governance.
基金funded by the National Natural Science Foundation of China(42371219)the Key Natural Science Foundation of Gansu Province(24JRRA135)the Oasis Scientific Research Achievements Breakthrough Action Plan Project of Northwest Normal University(NWNU-LZKX-202302).
文摘Due to irrational human activities and extreme climate,the Qinghai-Xizang Plateau,China,faces a serious threat of desertification.Desertification has a detrimental effect on the ecological environment and socioeconomic development.In this study,the desertification sensitivity index(DSI)model was established by integrating the spatial distance model and environmentally sensitive area index evaluation method,and then the model was used to quantitatively analyze the spatial and temporal characteristics of desertification sensitivity of the Qinghai-Xizang Plateau from 1990 to 2020.The results revealed that:(1)a general increasing tendency from southeast to northwest was identified in the spatial distribution of desertification sensitivity.The low-sensitivity areas were mostly concentrated in the Hengduan and Nyaingqêntanglha mountains and surrounding forest and meadow areas.The high-sensitivity areas were located mainly in the Kunlun and Altun mountains and surrounding decertified areas.The center of gravity of all types of desertification-sensitive areas moved to the northwest,and the desertification sensitivity showed a decreasing trend as a whole;(2)the area of highly sensitive desertification areas decreased by 8.37%,with extreme sensitivity being the largest change among the sensitivity types.The desertification sensitivity transfer was characterized by a greater shift to lower sensitivity levels(24.56%)than to higher levels(2.03%),which demonstrated a declining trend;(3)since 1990,the change in desertification sensitivity has been dominated by the stabilizing type Ⅰ(29.30%),with the area of continuously increasing desertification sensitivity accounting for only 1.10%,indicating that the management of desertification has achieved positive results in recent years;and(4)natural factors have had a more significant impact on desertification sensitivity on the Xizang Plateau,whereas socioeconomic factors affected only localized areas.The main factors influencing desertification sensitivity were vegetation drought tolerance and aridity index.Studying spatiotemporal variations in desertification sensitivity and its influencing factors can provide a scientific foundation for developing strategies to control desertification on the Qinghai-Xizang Plateau.Dividing different desertification-sensitive areas on the basis of these patterns of change can facilitate the formulation of more targeted management and protection measures,contributing to ecological construction and sustainable economic development in the area.
基金supported by the National Natural Science Foundation of China(32370386,32070372,and 32200295)Science Foundation for Distinguished Young Scholars of Shaanxi Province(2023-JC-JQ-22)+4 种基金Basic Research Project of Shaanxi Academy of Fundamental Science(22JHZ005)Shaanxi Key Research and Development Program(2024NC-YBXM-064)Science and Technology Program of Shaanxi Academy of Science(2023K-49,2023K-26,and 2019K-06)Shaanxi Forestry Science and Technology Innovation Key Project(SXLK2023-02-20)Qinling Hundred Talents Project of Shaanxi Academy of Science(Y23Z619F17).
文摘Intraspecific genetic variance and gene flow can support the adaptive evolution of species challenged by climate shifts or novel environmental conditions.Less well understood is how genome organization and gene flow interact in closely related species during evolutionary divergence and differentiation.Here we conducted genomic footprint analyses to determine how three species of Pterocarya(P.stenoptera,P.hupehensis,and P.macroptera),which are sympatric but occupy different elevational niches,adapted to the heterogeneous environment of the Qinling-Daba Mountains,China.We identified candidate genes for environmental adaptation(i.e.,PIEZO1,WRKY39,VDAC3,CBL1,and RAF),and also identified regions of gene introgression between P.hupehensis and P.macroptera that show lower genetic load and higher genetic diversity than the rest of their genomes.The same introgressed regions are notably situated in areas of minimal genetic divergence yet they are characterized by elevated recombination rates.We also identified candidate genes within these introgressed regions related to environmental adaptation(TPLC2,CYCH;1,LUH,bHLH112,GLX1,TLP-3,and ABC1).Our findings have thus clarified the important role of gene flow in ecological adaptation and revealed genomic signatures of past introgression.Together,these findings provide a stronger theoretical basis for understanding the ecological adaptation and conservation of Quaternary relict woody plants in East Asia.
基金financially supported by the National Key R&D Program of China(2024YFE0101100)the National Natural Science Foundation of China(22475112,22305132,22305155)+1 种基金the China Postdoctoral Science Foundation(2023M732323)the Postdoctoral Fellowship Program of CPSF(GZC20231679).
文摘Metal(oxide)-zeolite bifunctional catalysts have been the subject of considerable attention from researchers in both academic and industry,due to their superior activity and stability in various heterogeneous catalytic processes[1–3].Based on the different metal loading sites,these bifunctional catalysts can be categorized as follows:(a)metal species loaded on the outer surface of zeolite crystals,(b)metal species encapsulated within the channels or cavities of zeolites,and(c)metal species incorporated into the zeolite framework(Fig.1).Metal species in type(b)and(c)samples are stabilized by the zeolite frameworks,resulting in excellent thermal and hydrothermal stability during catalytic reactions,especially under harsh conditions,as well as unique shape-selectivity.However,the complex synthesis procedures make large-scale preparation of these catalysts impractical.In contrast,a type(a)sample can be achieved via the simple impregnation;nevertheless,migration of metal species and their aggregation into larger particles often occur during the calcination and reduction processes.
基金Under the auspices of National Natural Science Foundation of China(No.42271222)Natural Science Foundation of Gansu Province(No.22JR5RA130)。
文摘Rural resilience,a core capability for addressing systemic risks and enabling sustainable development,is increasingly vital to promoting urban-rural integrated development and rural revitalization strategies.However,current research lacks exploration of the collaborative mechanisms between rural economic resilience(RER)and rural social resilience(RSR)in ecologically vulnerable areas.Based on the practical context of rural sustainable development in such regions,this study investigates the interaction between RER and RSR from a resilience coordination perspective.In this paper,a rural resilience evaluation framework for collaborative development of economic and social resilience was established.By employing the coupling coordination degree model,obstacle degree model,and equilibrium entropy model,this paper examines the synergies,constraints,and potential of rural resilience subsystems in Jinchang City,Gansu Province,China,in 2020.The results reveal that:1)RER contributes to RSR by stabilizing the economy,enhancing community adaptability,and driving modernization.In turn,RSR strengthens RER by mitigating instability,building social capital,and fostering confidence—together forming a mutually reinforcing coupling mechanism.2)The rural economic and social resilience level in Jinchang City remains generally low with spatially clustered patterns,while the coupling coordination degree is at an intermediate level overall,with 62.59%of villages exhibiting unbalanced development between rural economic and social resilience.3)RER and RSR demonstrate synergistic degradation in ecologically vulnerable areas,where low-level rural economic and social resilience induce integrated systemic deterioration.4)Considering the unbalanced development of rural economic and social resilience in ecologically fragile areas,differentiated coordination pathways are proposed for three village typologies:RER-lagging villages,RSR-lagging villages,and villages where RER and RSR develop synchronously but lack effective coordination.These findings offer spatial governance strategies and practical guidance for enhancing rural resilience and advancing sustainable development in ecologically vulnerable regions.
基金supported by grants from the National Natural Science Foundation of China(Grant Nos.32070616 and 82170794).
文摘Background:Small ubiquitin-like modifier(SUMO)-specific proteases(SENPs)cleave the isopeptidic bond between SUMO1/2/3 and protein substrates,thus regulating the structure,activity,and lifetime of a variety of proteins.Recently,accumulating evidence has suggested that SENPs play a role in the initiation and progression of human cancers.Nevertheless,the potential role of the SENP family of proteins in liver cancer has yet to be fully elucidated.Methods:This study conducted a comprehensive bioinformatics analysis of the SENP family in liver cancer,including differential expression profiling,survival analysis,mutation and copy number variations(CNVs)assessment,immune infiltration and drug sensitivity correlation,functional enrichment analyses using data from The Cancer Genome Atlas(TCGA),Clinical Proteomic Tumor Analysis Consortium(CPTAC),LinkedOmics,and other public databases.Furthermore,we performed in vitro experiments using Huh-7 and Hep-3B cell lines to investigate the functional roles of SENP1 and SENP3 in hepatocellular carcinoma cell proliferation,colony formation,and migration.Results:Our results indicated that SENP1,3,and 7 were significantly overexpressed in liver hepatocellular carcinoma(LIHC).Elevated expressions of SENP1,3,and 7 are positively correlated with poor overall survival(OS)in LIHC patients.In addition,SENP1,3,and 7 expressions are related to immune infiltration and drug sensitivity.SENP1,3,and 7 co-expressed genes were enriched in mitochondrial function,ribosomal translation,and cell cycle control.Conclusion:SENP1,3,and 7 are prognostic biomarkers and potential therapeutic targets for LIHC.Knockdown of SENP1 and SENP3 inhibited the proliferation,clonogenicity,and migration of hepatocellular carcinoma cells.
基金funded by the National Natural Science Foundation of China (42071047)Innovation Fund Project for College Teachers in Gansu Province (2025A-008)+1 种基金Research Capability Enhancement Plan for Young Teachers at Northwest Normal University (NWNU-LKQN2024-19)Basic Research Innovation Group Project of Gansu Province (22JR5RA129)。
文摘Under current climate warming, the growth resilience of plantation forests after extreme droughts has garnered increasing attention. Platycladus orientalis Linn. is an evergreen tree species commonly used for afforestation, and the stability of P. orientalis plantation forests in the Loess Hilly region directly affects the ecological and environmental security of the entire Loess Plateau of China.However, systematic analyses of the growth resilience of P. orientalis plantation forests after extreme droughts along precipitation gradients remain scarce. In this study, we collected tree ring samples of P.orientalis along a precipitation gradient(255, 400, and 517 mm) from 2021 to 2023 and used dendroecological methods to explore the growth resilience of P. orientalis to drought stress on the Loess Plateau. Our findings revealed that the growth resilience of P. orientalis increased with increasing precipitation, enabling the trees to recover to the pre-drought growth levels. In regions with low precipitation(255 mm), the plantation forests were more sensitive to extreme droughts, struggling to recover to previous growth levels, necessitating conditional artificial irrigation. In regions with medium precipitation(400 mm), the growth of P. orientalis was significantly limited by drought stress and exhibited some recovery ability after extreme droughts, therefore warranting management through rainwater harvesting and conservation measures. Conversely, in regions with high precipitation(517 mm), the impacts of extreme droughts on P. orientalis plantation forests were relatively minor. This study underscored the need for targeted strategies tailored to different precipitation conditions rather than a "one-size-fits-all" approach to utilize precipitation resources effectively and maximize the ecological benefits of plantation forests. The findings will help maintain the stability of plantation forests and improve their ecosystem service functions in arid and semi-arid areas.
基金supported by the National Natural Science Foundation of China(Grant No.42371038)the Basic Research Innovation Group Project of Gansu Province(No.22JR5RA129)+1 种基金the 2022 Major Scientific Research Project Cultivation Program of Northwest Normal University(No.WNU-LKZD2022-04)the 2022 Northwest Normal University Graduate Research Grant Program(No.2022KYZZ-B066).
文摘The survival and mortality of conifer trees in response to climate change,particularly drought stress,have received considerable attention.However,it is crucial to explore the growth dynamics of the same conifer species in response to climate change in different climatic habitats.In this study,we aimed to quantify variations in the radial growth processes of conifer species,analyze their resilience during drought periods under different climatic habitats,and assess the impact of climate adaptation on conifer growth.We focused on two conifer species,Picea crassifolia(spruce)and Pinus tabuliformis(pine),which are distributed in both a humid habitat and a dry habitat in the northeastern Tibetan Plateau.Growth and resilience dynamics were identified across both climatic habitats and the contributions of temperature and moisture to the growth of the two species were simulated under drought stress using the VS-oscilloscope model.Spruce growth exhibited significant variability between climatic habitats.Specifically,the spruce growth rate declined in response to drought in the dry habitat(-0.91 cm^(2)per decade,p<0.01).In contrast,pine growth remained relatively stable(humid habitat:-0.03 cm^(2)per decade;dry habitat:0.25 cm^(2)per decade,p>0.01),although it still responded to stress during the growing season(p<0.05).Furthermore,spruce displayed reduced resistance during stress in dry habitats(-30.11%),while pine exhibited an enhanced recovery of growth rates to ensure survival(+39.62%).The climate adaptation strategies of the species were linked to the contribution of temperature and moisture to their growth rates.Moisture is critical for the growth recovery of both conifers in dry habitats when temperature-associated growth displays a‘bimodal’pattern during the growing season.These findings have significant ecological implications for understanding conifer forest processes in the context of global climate change.
