In-situ poly(1,3-dioxolane)(PDOL)-based electrolyte has received extensive attention in the research of lithium metal batteries due to its high stability to lithium anode and simple processing.However,it is still face...In-situ poly(1,3-dioxolane)(PDOL)-based electrolyte has received extensive attention in the research of lithium metal batteries due to its high stability to lithium anode and simple processing.However,it is still faced with defects such as low intrinsic ionic conductivity,a narrow electrochemical window,and poor thermal stability.A crosslinking and fluorination molecular design strategy toward PDOL is proposed to tackle the issues above.The amorphous crosslinked structure effectively improves ionic conductivity by inhibiting long-chain crystallization.Especially,the antioxidant–CF_(3)groups,stable crosslinked structure,and reduced terminal hydroxyl groups significantly enhance the electrochemical oxidation stability with a superb high-voltage window of 4.7 V.In addition,the designed electrolyte also exhibits obviously improved thermal stability with no deformation at 120°C for 5 min.Furthermore,the semi-solid NCM811||Li batteries exhibit a favourable capacity retention of 88.8%after 150 cycles at 0.5 C.Even assembled with NCM622 cathode working at 4.5 V,the semi-solid batteries can still show a satisfactory capacity retention of 85.3%after 100 cycles at 0.5 C.Also,a 0.1 Ah NCM811||Li pouch cell with active materials loading of 9 mg/cm2 demonstrates satisfactory cycling stability and working ability,which shows promising practical application prospects.展开更多
Zinc(Zn)deficiency is a global health issue,exacerbated by low Zn concentration and poor bioavailability in rice,primarily due to phytic acid(PA)interference.In this study,four doubled haploid(DH)progenies(DH1,DH11,DH...Zinc(Zn)deficiency is a global health issue,exacerbated by low Zn concentration and poor bioavailability in rice,primarily due to phytic acid(PA)interference.In this study,four doubled haploid(DH)progenies(DH1,DH11,DH18,and DH29)with distinct Zn and PA profiles were used to evaluate the effects of varying degrees of milling(DOM)on Zn bioavailability.Results showed DOM followed a double-exponential decay pattern(R^(2)>0.99)with milling time,varying among the four DH lines under identical milling conditions.As DOM increased,Zn,PA,and phosphorus(P)concentrations decreased progressively.展开更多
Constructing a framework carrier to stabilize protein conformation,induce high embedding efficiency,and acquire low mass-transfer resistance is an urgent issue in the development of immobilized enzymes.Hydrogen-bonded...Constructing a framework carrier to stabilize protein conformation,induce high embedding efficiency,and acquire low mass-transfer resistance is an urgent issue in the development of immobilized enzymes.Hydrogen-bonded organic frameworks(HOFs)have promising application potential for embedding enzymes.In fact,no metal involvement is required,and HOFs exhibit superior biocompatibility,and free access to substrates in mesoporous channels.Herein,a facile in situ growth approach was proposed for the self-assembly of alcohol dehydrogenase encapsulated in HOF.The micron-scale bio-catalytic composite was rapidly synthesized under mild conditions(aqueous phase and ambient temperature)with a controllable embedding rate.The high crystallinity and periodic arrangement channels of HOF were preserved at a high enzyme encapsulation efficiency of 59%.This bio-composite improved the tolerance of the enzyme to the acid-base environment and retained 81%of its initial activity after five cycles of batch hydrogenation involving NADH coenzyme.Based on this controllably synthesized bio-catalytic material and a common lipase,we further developed a two-stage cascade microchemical system and achieved the continuous production of chiral hydroxybutyric acid(R-3-HBA).展开更多
As the commercialization of the fifth gen-eration communication(5G)is sped up,its system testing scheme is vital for the successful deployment of 5G.Especially,5G relies on the scale-increased multiple-input-multiple ...As the commercialization of the fifth gen-eration communication(5G)is sped up,its system testing scheme is vital for the successful deployment of 5G.Especially,5G relies on the scale-increased multiple-input-multiple output(MIMO)technique to improve its capacity and coverage.Thus,testing new functions of the 5G MIMO system accurately and ef-ficiently,including beamforming(beam-tracking with movement)and multiple-user(MU)multiplexing,is a challenging task.This paper tries to construct a lab-oratorial hardware and conduct equipment-controlled field testing.Firstly,the testing scheme is presented,which is composed of the framework,the channel models and the validation methods.Then,the channel model principles are explained in detail due to its di-rect influence on the testing accuracy.Specifically,we utilize the spatial consistency and the multi-link cor-relation properties to emulate the high-speed dynamic time-varying(HDT)and the multiple-cell(MC)-MU-MIMO channels.Finally,the above testing scheme is verified in a Shanghai 5G field experiment with the practical commercial equipment and the channel em-ulator.The results show that the 5G new functions are tested accurately and efficiently by switching the channel emulation configurations.展开更多
With the increasing consumption of non renewable resources such as oil,the traditional polymer manufacturing industry that relies on fossil resources is facing unprecedented challenges.The design,synthesis,and recycli...With the increasing consumption of non renewable resources such as oil,the traditional polymer manufacturing industry that relies on fossil resources is facing unprecedented challenges.The design,synthesis,and recycling of renewable and environmentally friendly bio-based polymers as alternatives to petroleum based polymers have become hot topics in research and industrial fields.Biomass has been used as a raw material to design and synthesize closed-loop recyclable polymers,which is of great significance in addressing the waste of resources and negative impact on the environment in the traditional polymer preparation process.This review summarized recent advances in the design,synthesis,and properties of closed-loop recyclable bio-based polymers,focusing on the sustainability and recyclability of bio-based materials,followed by a brief discussion of the potential applications of closed-loop recyclable bio-based polymers in emerging applications such as 3D printing and friction electric nanogenerators.In addition,perspectives and recommendations for future research on closedloop recyclable bio-based polymers were presented.展开更多
With the rapid growth of the low-altitude economy,the demand for typical low-altitude ap-plications has accelerated the advancement of inte-grated sensing and communications(ISAC)networks.This paper begins by analyzin...With the rapid growth of the low-altitude economy,the demand for typical low-altitude ap-plications has accelerated the advancement of inte-grated sensing and communications(ISAC)networks.This paper begins by analyzing representative ap-plication scenarios to clarify the core requirements of the low-altitude economy for modern ISAC net-works.By investigating the distinctive characteris-tics of ISAC networks in low-altitude environments,it presents a comprehensive analysis of key challenges and identifies four major issues:challenges in pre-cise target detection,interference management,in-consistent sensing and communication coverage,and the complexity of air-ground coordination and han-dover.Based on fundamental theories and principles,the paper proposes corresponding solutions,encom-passing advanced technologies for precise target de-tection and recognition,high-reliability networked de-tection,robust interference management,and seamless air-ground collaboration.These solutions aim to es-tablish a solid foundation for the future development of intelligent low-altitude networks and ensure effec-tive support for emerging applications.展开更多
Tyrosine residues in proteins can be nitrated to form 3-nitrotyrosine(3-NT)under the influence of ozone(O_(3))and nitrogen dioxide(NO_(2))in the air,which may introduce health impacts.A selective and sensitive enzyme-...Tyrosine residues in proteins can be nitrated to form 3-nitrotyrosine(3-NT)under the influence of ozone(O_(3))and nitrogen dioxide(NO_(2))in the air,which may introduce health impacts.A selective and sensitive enzyme-linked-immunoassay(ELISA)method was developed to determine 3-NT in modified model protein(bovine serum albumin,BSA)and ambient aerosol samples.The nitration degrees(NDs)of BSA in the exposure experiments with different durations were detected by both the ELISA and spectrophotometric methods(i.e.,ND_(ELISA) and ND_(SEC-PDA)),which show good coincidence.The kinetic investigation by both ΔND_(ELISA) and ΔND_(SEC-PDA) in the exposure experiments shows that the rate coefficients(k)of the pseudo-first-order kinetic rate reactions of protein nitration were comparable.These results indicate that direct detection of 3-NT by the ELISA method can be applied for laboratory exposure samples analysis for kinetic studies.Based on the selective detection of 3-NT,ND_(ELISA) provides a promising measure for the assessment of ND in model proteins.3-NT was alsomeasured in PM_(2.5) samples in summer in Guangzhou,southern China,ranging from 10.1 to 404 pg/m^(3),providing clear evidence of protein nitration in ambient aerosols.We further proposed that 3-NT/protein can be used as a proxy to evaluate protein nitration in ambient aerosols.A significant correlationwas observed between 3-NT/protein and O_(3),confirming the crucial role of O_(3) in protein nitration.Our results show that the direct detection of 3-NT by the ELISA method can be more widely applied in the laboratory and field-based studies for understanding the mechanisms of protein nitration.展开更多
Extremely large-scale multiple-input multiple-output(XL-MIMO)is regarded as a promis-ing technology for next-generation communication systems.However,this will expand the near-field(NF)range,rendering more users more ...Extremely large-scale multiple-input multiple-output(XL-MIMO)is regarded as a promis-ing technology for next-generation communication systems.However,this will expand the near-field(NF)range,rendering more users more likely to be located in the NF region.In this paper,we aim to answer two questions:What are the new characteristics of the NF channel?Is it necessary to develop new transciver techniques to maintain system performance within the NF region?To this end,we first review current NF channel models and analyze the differences between the existing 3GPP TR 38.901 channel model and the NF channel model,including the spherical wavefront and spatially non-stationarity.Then,we provide ex-amples on how these differences affect the XL-MIMO system performance in terms of beamforming gain and achievable rate.Simulation results demonstrate that,when using far-field(FF)technique under the NF channel,the maximum normalized beam gain loss is less than 3 dB for most users in the NF region de-fined by Rayleigh distance.Moreover,the achievable rate loss of beam training is less than 3%compared to that realized by NF technique.Finally,we demonstrate the necessity of employing NF transceiver techniques based on simulation results.展开更多
Intelligent manufacturing(IM),a driving force behind the fourth industrial revolution,is reshaping the manufacturing sector by enhancing productivity,efficiency,and sustainability.Despite the rapid technological advan...Intelligent manufacturing(IM),a driving force behind the fourth industrial revolution,is reshaping the manufacturing sector by enhancing productivity,efficiency,and sustainability.Despite the rapid technological advancements in IM,comprehensive bibliometric reviews remain limited.This article systematically reviews the latest research in IM,addressing emerging hotspots,key technologies,and their applications across the entire product manufacturing cycle.Bibliometric analysis is employed to identify research trends visualize publication volume,collaboration patterns,research domains,co-citations,and emerging areas of interest.The article then examines key technologies supporting IM,including sensors,the Internet of Things(IoT),big data analytics,cloud computing,artificial intelligence(AI),digital twins,and virtual reality(VR)/augmented reality(AR).Furthermore,it explores the application of these technologies throughout the manufacturing cycle-from intelligent reliability design,material transportation and tracking,to intelligent planning and scheduling,machining and fabrication,monitoring and maintenance,quality inspection and control,warehousing and management,and sustainable green manufacturing—through specific case studies.Lastly,the article discusses future research directions,highlighting the increasing global market and the need for enhanced interdisciplinary collaboration,technological integration,computing power upgrades,and attention to security and privacy in IM.This study provides valuable insights for scholars and serves as a guide for future research and strategic investment decisions,offering a comprehensive view of the IM field.展开更多
The traditional nanozymes-based ratiometric fluorescence sensing platforms usually necessitate the supplementary addition of fluorescent probes,therefore greatly restricting its convenient and broad application.In thi...The traditional nanozymes-based ratiometric fluorescence sensing platforms usually necessitate the supplementary addition of fluorescent probes,therefore greatly restricting its convenient and broad application.In this study,a highly sensitive and selective ratiometric fluorescence platform for alkaline phosphatase(ALP)detection was established,only employing Prussian blue(PB)nanozymes and a commercially available chromogen of o-phenylenediamine(OPD).PB nanozymes with remarkable peroxidaselike(POD-like)activity can effectively catalyze OPD chromogen to yield 2,3-diaminophenazine(OPDox)with an intense yellow fluorescence at 573 nm emission peak.Target ALP can facilitate ascorbic acid 2-phosphate(AAP)dephosphorylation to generate phosphate and ascorbic acid(AA).Significantly,both these two resultant hydrolysis products could effectively decrease the OPDox generation via a dualpath based inhibition on the PB nanozymes POD-like activity.On the other hand,the generated dehydroascorbic acid(DHAA)from AA oxidation would exclusively react with OPD chromogen to yield3-(dihydroxyethyl)furo[3,4-b]quinoxaline-1-one(DFQ)with a strong blue fluorescent signal at 434nm,which further providing a significant enhancement on the sensing selectivity of ALP detection.As a result,an increased yellow fluorescence of OPDox and decreased blue fluorescence of DFQ could be clearly observed with different ALP addition.A robust linear relationship between the fluorescence ratio of F_(434)/F_(573)and ALP activity ranging from 0.25U/L to 6U/L was obtained,with a low detection limit of 0.112 U/L.This proposed method demonstrates high sensitivity,excellent selectivity,cost-effectiveness,and operational simplicity,yet enabling an effective detection of ALP levels in human serum.展开更多
The octahedral tunnel-like three-dimensional(3D)structure of V_(2)O_(3)enables fast metal ion(de)intercalation and high capacity in aqueous zinc-ion batteries(ZIBs),but suffers from phase transition-induced structural...The octahedral tunnel-like three-dimensional(3D)structure of V_(2)O_(3)enables fast metal ion(de)intercalation and high capacity in aqueous zinc-ion batteries(ZIBs),but suffers from phase transition-induced structural degradation and capacity fading.Herein,we demonstrate that the undesirable phase transition of V_(2)O_(3)can be effectively suppressed through a new La^(3+)doping strategy and its implementation as a robust ZIBs cathode.The introduced La^(3+)ions not only can increase cell volume and expand ion channels of V_(2)O_(3)but also offer plentiful Zn^(2+)storage sites and promote the transport of Zn^(2+)ions and electrons.In particular,the doping of La^(3+)maintains the octahedral tunnel structure of V_(2)O_(3)and prevents its phase transition during(dis)charge,which improves the cycle stability of the V_(2)O_(3)cathode in ZIBs.By virtue of the above favorable factors,La-doped V_(2)O_(3)electrode presents an impressive discharge capacity of632.1 m Ah g^(-1)at 0.1 A g^(-1)after 100 cycles with a capacity retention up to 93.1%.Even at 10 A g^(-1),its discharge capacity remains at 342.7 mAh g^(-1)after 1000 cycles with a capacity attenuation of solely0.0069%per cycle.This work establishes rare-earth cation doping as a universal paradigm to reconcile structural stability and multi-electron redox activity in high-capacity battery electrodes.展开更多
In this work,we proposed a strategy for the hydrolysis of native corn starch after the treatment of corn starch in an ionic liquid aqueous solution,and it is an awfully“green”and simple means to obtain starch with l...In this work,we proposed a strategy for the hydrolysis of native corn starch after the treatment of corn starch in an ionic liquid aqueous solution,and it is an awfully“green”and simple means to obtain starch with low molecular weight and amorphous state.X-ray diffraction results revealed that the natural starch crystalline region was largely disrupted by ionic liquid owing to the broken intermolecular and intramolecular hydrogen bonds.After hydrolysis,the morphology of starch changed from particles of native corn starch into little pieces,and their molecular weight could be effectively regulated during the hydrolysis process,and also the hydrolyzed starch samples exhibited decreased thermal stability with the extension of hydrolysis time.This work would counsel as a powerful tool for the development of native starch in realistic applications.展开更多
Carbon superstructures with multiscale hierarchies and functional attributes represent an appealing cathode candidate for zinc hybrid capacitors,but their tailor-made design to optimize the capacitive activity remains...Carbon superstructures with multiscale hierarchies and functional attributes represent an appealing cathode candidate for zinc hybrid capacitors,but their tailor-made design to optimize the capacitive activity remains a confusing topic.Here we develop a hydrogen-bond-oriented interfacial super-assembly strategy to custom-tailor nanosheet-intertwined spherical carbon superstructures(SCSs)for Zn-ion storage with double-high capacitive activity and durability.Tetrachlorobenzoquinone(H-bond acceptor)and dimethylbenzidine(H-bond donator)can interact to form organic nanosheet modules,which are sequentially assembled,orientally compacted and densified into well-orchestrated superstructures through multiple H-bonds(N-H···O).Featured with rich surface-active heterodiatomic motifs,more exposed nanoporous channels,and successive charge migration paths,SCSs cathode promises high accessibility of built-in zincophilic sites and rapid ion diffusion with low energy barriers(3.3Ωs-0.5).Consequently,the assembled Zn||SCSs capacitor harvests all-round improvement in Zn-ion storage metrics,including high energy density(166 Wh kg-1),high-rate performance(172 m Ah g^(-1)at 20 A g^(-1)),and long-lasting cycling lifespan(95.5%capacity retention after 500,000 cycles).An opposite chargecarrier storage mechanism is rationalized for SCSs cathode to maximize spatial capacitive charge storage,involving high-kinetics physical Zn^(2+)/CF_(3)SO_(3)-adsorption and chemical Zn^(2+)redox with carbonyl/pyridine groups.This work gives insights into H-bond-guided interfacial superassembly design of superstructural carbons toward advanced energy storage.展开更多
A detailed investigation was carried out to understand how the variations in configurations of the spiroannulated 6-6-6-5-5 pentacyclic diastereoisomers,the key intermediates for the synthesis of two C30 terpene quino...A detailed investigation was carried out to understand how the variations in configurations of the spiroannulated 6-6-6-5-5 pentacyclic diastereoisomers,the key intermediates for the synthesis of two C30 terpene quinonemethides and their stereoisomers,impact the reactivity of cyclopropanation.The configurations at C9,C8,and C14 for all four pentacyclic diastereoisomers involved in the diastereoisomeric mixture were determined through a combination of suitable chemical derivatization and multiple NMR spectroscopic analyses.Based on the defined configuration,the 3D structures of these diastereoisomers were optimized by density functional theory(DFT)calculation.These investigations provide reasonable supports,mainly from the steric considerations,for understanding why different diastereoisomers exhibit markedly different reactivity,as well as regio-and stereo-selectivity for cyclopropanation.In addition,the mechanism for the construction of the spiroannulated 6-6-6-5-5 pentacyclic scaffold via intramolecular Michael/aldol cascade was also investigated by deuterium labeling experiments.展开更多
NiFe-layered double hydroxides(NiFe-LDHs)are among the most promising earth-abundant electrocatalysts for the oxygen evolution reaction(OER)in alkaline media.However,their practical application is hindered by intrinsi...NiFe-layered double hydroxides(NiFe-LDHs)are among the most promising earth-abundant electrocatalysts for the oxygen evolution reaction(OER)in alkaline media.However,their practical application is hindered by intrinsic activity limitations and poor stability,primarily due to the asymmetric adsorption of oxygen intermediates.To overcome this,the binding strength must be synergistically tuned to a moderate level to optimize catalytic performance.Here,we engineered NiFeCoCr LDH through Co doping to enhance electrical conductivity and controlled Cr leaching to introduce cationic vacancies for modulating intermediate binding strength in NiFe LDH.X-ray absorption near-edge structure and extended X-ray absorption fine structure analyses reveal that NiFe-LDH with Co doping and Cr vacancies modulates the Ni oxidation state and local coordination environment,leading to a balanced electronic structure and enhanced structural complexity around the Ni sites.Additionally,these vacancies can trap OH^(-)/H_(2)O species,which can serve as a reservoir for OH^(-) transfer,facilitating the rapid formation of OER intermediates and enhancing catalytic performance at high current densities.As a result,V_(Cr)-NiFeCo LDH achieves 1.6 A cm^(-2)current density at 1.7 V vs.RHE while maintaining stable operation for over 1000 h at 500 mA cm^(-2).Density functional theory(DFT)calculations validate the synergistic effects of Co doping and Cr-induced vacancies on intermediate binding energies and improved OER kinetics.Overall,this work presents a rational design strategy to simultaneously enhance the activity and durability of NiFe-based OER catalysts for their application in high-performance alkaline water electrolysis.展开更多
The rapid development of information technology and accelerated digitalization have led to an explosive growth of data across various fields.As a key technology for knowledge representation and sharing,knowledge graph...The rapid development of information technology and accelerated digitalization have led to an explosive growth of data across various fields.As a key technology for knowledge representation and sharing,knowledge graphs play a crucial role by constructing structured networks of relationships among entities.However,data sparsity and numerous unexplored implicit relations result in the widespread incompleteness of knowledge graphs.In static knowledge graph completion,most existing methods rely on linear operations or simple interaction mechanisms for triple encoding,making it difficult to fully capture the deep semantic associations between entities and relations.Moreover,many methods focus only on the local information of individual triples,ignoring the rich semantic dependencies embedded in the neighboring nodes of entities within the graph structure,which leads to incomplete embedding representations.To address these challenges,we propose Two-Stage Mixer Embedding(TSMixerE),a static knowledge graph completion method based on entity context.In the unit semantic extraction stage,TSMixerE leveragesmulti-scale circular convolution to capture local features atmultiple granularities,enhancing the flexibility and robustness of feature interactions.A channel attention mechanism amplifies key channel responses to suppress noise and irrelevant information,thereby improving the discriminative power and semantic depth of feature representations.For contextual information fusion,a multi-layer self-attentionmechanism enables deep interactions among contextual cues,effectively integrating local details with global context.Simultaneously,type embeddings clarify the semantic identities and roles of each component,enhancing the model’s sensitivity and fusion capabilities for diverse information sources.Furthermore,TSMixerE constructs contextual unit sequences for entities,fully exploring neighborhood information within the graph structure to model complex semantic dependencies,thus improving the completeness and generalization of embedding representations.展开更多
Sichuan sausages with moisture contents of 40%,45%,50%,and 60% were stored at-18℃for durations of 0,2,4,6,and 8 weeks to evaluate the effect of moisture content on the quality attributes of Sichuan sausages during fr...Sichuan sausages with moisture contents of 40%,45%,50%,and 60% were stored at-18℃for durations of 0,2,4,6,and 8 weeks to evaluate the effect of moisture content on the quality attributes of Sichuan sausages during frozen storage.Product indicators including pH,colour,thiobarbituric acid reactive substances(TBARS),total volatile basic nitrogen(TVB-N),texture,electronic nose(E-nose)response,and water-holding capacity(thawing and cooking losses)were determined.The results indicated that as storage time increased,water retention in Sichuan sausages with different moisture contents decreased,while the degree of protein and lipid oxidation increased.This led to an increase in pH value,a colour shift from red-bright to grey-brown,and a deterioration in palatability.Among the samples,sausages with 50% moisture content exhibited the lowest thawing and cooking losses,indicating superior water-holding capacity.After 8 weeks of storage,TBARS and TVB-N values for the 50% moisture group were 19.5%and 2.5%lower,respectively,than those of the 40%and 45%moisture groups,indicating a reduced degree of oxidation.Furthermore,Sichuan sausage with 50%moisture content demonstrated an appropriate pH and colour difference,along with excellent texture and flavour,as evidenced by its higher toughness and satisfactory hardness.In conclusion,Sichuan sausage with 50% moisture content demonstrated the highest overall quality under frozen storage conditions.展开更多
Polyolefins with intrinsic antimicrobial properties have attracted significant attention.In this study,various ion-functionalized polyolefins were successfully constructed by incorporating iodine-containing comonomers...Polyolefins with intrinsic antimicrobial properties have attracted significant attention.In this study,various ion-functionalized polyolefins were successfully constructed by incorporating iodine-containing comonomers into a polypropylene backbone,followed by post-functionalization strategies that utilized the conversion reactions of pre-introduced iodine groups.The introduction of ionic groups induced notable changes in both the thermal properties and the melt rheological behavior of the material.The dual crosslinking mechanism based on ionic interactions and polypropylene crystallization significantly enhanced the mechanical strength of the material.In addition,imidazolium-based ionomers exhibit highly effective antimicrobial properties against Gram-negative Escherichia coli and Gram-positive Staphylococcus aureus.Specifically,the P5-CCl_(3)CO_(2)^(−)sample achieved a sterilization rate of 99.99%against both bacteria and maintained a high bactericidal efficacy of above 90%,even after continuous supplementation with fresh bacterial solutions for 15 days.Consequently,this polypropylene-based ionomer,which combines excellent mechanical strength with outstanding antimicrobial performance,demonstrates substantial application potential in children’s toys,food packaging,and medicine.展开更多
AIM:To investigate the association between functionaloutcomes and postoperative patient satisfaction 5y aftersmall incision lenticule extraction(SMILE)and femtosecondlaser-assisted in situ keratomileusis(FS-LASIK).MET...AIM:To investigate the association between functionaloutcomes and postoperative patient satisfaction 5y aftersmall incision lenticule extraction(SMILE)and femtosecondlaser-assisted in situ keratomileusis(FS-LASIK).METHODS:This is a cross-sectional study.Thepatients underwent basic ophthalmic examinations,axiallength measurement,wide-field fundus photography,andaccommodation function testing.Behavioral habits datawere collected using a self-administered questionnaire,andvisual symptoms were assessed with the Quality of Vision(QoV)questionnaire.Postoperative satisfaction was alsorecorded.RESULTS:Totally 410 subjects[820 eyes,160males(39.02%)and 250 females(60.98%)]who hadundergone SMILE or FS-LASIK 5y ago were enrolled.Themean(standard deviation,SD)age of all patients was29.83y(6.69).The mean(SD)preoperative manifest SEwas-5.80(2.04)diopters(D;range:-0.88 to-13.75).Patient satisfaction at 5y after undergoing SMILE or FSLASIKwas 91.70%.Patients were categorized into twogroups:dissatisfied group and satisfied group.Significantdifferences were observed between the two groups in termsof age(P=0.012),sex(P=0.021),preoperative degreeof myopia(P=0.049),postoperative visual symptoms(frequency,P=0.043;severity,P<0.001;bothersome,P=0.018),difficulty driving at night(P=0.001),andaccommodative amplitude(AMP,P=0.020).Multivariateanalysis confirmed that female sex(P=0.024),severityof visual symptoms(P=0.009),and difficulty driving atnight(P=0.006)were significantly associated with lowersatisfaction.The dissatisfied group showed higher rates ofstarbursts,double or multiple images,and high myopia,but lower age.The frequency,severity,and bothersome ofdistortion exhibited decreased with increasing age.CONCLUSION:Patient satisfaction 5y after SMILEand FS-LASIK is high and stable.Difficulty driving at night,sex,and severity of visual symptoms are important factorsinfluencing patient satisfaction.Special attention should bepaid to younger highly myopic female patients,particularlythose with starbursts and double or multiple images.It is crucial to monitor postoperative visual outcomesand provide patients with comprehensive preoperativecounseling to enhance long-term satisfaction.展开更多
Path planning for Unmanned Aerial Vehicles(UAVs)in complex environments presents several challenges.Traditional algorithms often struggle with the complexity of high-dimensional search spaces,leading to inefficiencies...Path planning for Unmanned Aerial Vehicles(UAVs)in complex environments presents several challenges.Traditional algorithms often struggle with the complexity of high-dimensional search spaces,leading to inefficiencies.Additionally,the non-linear nature of cost functions can cause algorithms to become trapped in local optima.Furthermore,there is often a lack of adequate consideration for real-world constraints,for example,due to the necessity for obstacle avoidance or because of the restrictions of flight safety.To address the aforementioned issues,this paper proposes a dynamic weighted spherical particle swarm optimization(DW-SPSO)algorithm.The algorithm adopts a dual Sigmoid-based adaptive weight adjustment mechanism for balancing global exploration and local exploitation,as well as a lens-based opposition learning one to improve search flexibility and solution diversity.Simulation experiments on real digital elevation models demonstrate that DW-SPSO significantly outperforms recent state-of-the-art particle swarm optimization(PSO)variants in terms of path safety,smoothness,and convergence speed.The performance superiority is statistically validated by the Wilcoxon signed-rank test.The results confirm the algorithm’s effectiveness in generating high-quality UAV paths under diverse threat conditions,offering a robust solution for autonomous navigation systems.展开更多
基金the financial support from the National Natural Science Foundation of China (No. 52072390)the National High-Level Talents Special Support Program (Leading Talent of Technological Innovation)+2 种基金the China Postdoctoral Science Foundation (No. 2023M743648)the Young Scientists Fund of the National Natural Science Foundation of China (No. 52302330)the support from the Shanghai Emperor of Cleaning Hi-Tech Co.,LTD
文摘In-situ poly(1,3-dioxolane)(PDOL)-based electrolyte has received extensive attention in the research of lithium metal batteries due to its high stability to lithium anode and simple processing.However,it is still faced with defects such as low intrinsic ionic conductivity,a narrow electrochemical window,and poor thermal stability.A crosslinking and fluorination molecular design strategy toward PDOL is proposed to tackle the issues above.The amorphous crosslinked structure effectively improves ionic conductivity by inhibiting long-chain crystallization.Especially,the antioxidant–CF_(3)groups,stable crosslinked structure,and reduced terminal hydroxyl groups significantly enhance the electrochemical oxidation stability with a superb high-voltage window of 4.7 V.In addition,the designed electrolyte also exhibits obviously improved thermal stability with no deformation at 120°C for 5 min.Furthermore,the semi-solid NCM811||Li batteries exhibit a favourable capacity retention of 88.8%after 150 cycles at 0.5 C.Even assembled with NCM622 cathode working at 4.5 V,the semi-solid batteries can still show a satisfactory capacity retention of 85.3%after 100 cycles at 0.5 C.Also,a 0.1 Ah NCM811||Li pouch cell with active materials loading of 9 mg/cm2 demonstrates satisfactory cycling stability and working ability,which shows promising practical application prospects.
基金supported by the National Key Research and Development Program of China(Grant No.2022YFD1200702)the Sanya Fanxing Technology Special Program,China(Grant No.2024KJFX023)the Shandong Provincial Key Research and Development Program,China(Grant No.2023LZGCQY018).
文摘Zinc(Zn)deficiency is a global health issue,exacerbated by low Zn concentration and poor bioavailability in rice,primarily due to phytic acid(PA)interference.In this study,four doubled haploid(DH)progenies(DH1,DH11,DH18,and DH29)with distinct Zn and PA profiles were used to evaluate the effects of varying degrees of milling(DOM)on Zn bioavailability.Results showed DOM followed a double-exponential decay pattern(R^(2)>0.99)with milling time,varying among the four DH lines under identical milling conditions.As DOM increased,Zn,PA,and phosphorus(P)concentrations decreased progressively.
基金supported by the National Key Research and Development Program of China(2019YFA0905100)the National Natural Science Foundation of China(21991102,22378227).
文摘Constructing a framework carrier to stabilize protein conformation,induce high embedding efficiency,and acquire low mass-transfer resistance is an urgent issue in the development of immobilized enzymes.Hydrogen-bonded organic frameworks(HOFs)have promising application potential for embedding enzymes.In fact,no metal involvement is required,and HOFs exhibit superior biocompatibility,and free access to substrates in mesoporous channels.Herein,a facile in situ growth approach was proposed for the self-assembly of alcohol dehydrogenase encapsulated in HOF.The micron-scale bio-catalytic composite was rapidly synthesized under mild conditions(aqueous phase and ambient temperature)with a controllable embedding rate.The high crystallinity and periodic arrangement channels of HOF were preserved at a high enzyme encapsulation efficiency of 59%.This bio-composite improved the tolerance of the enzyme to the acid-base environment and retained 81%of its initial activity after five cycles of batch hydrogenation involving NADH coenzyme.Based on this controllably synthesized bio-catalytic material and a common lipase,we further developed a two-stage cascade microchemical system and achieved the continuous production of chiral hydroxybutyric acid(R-3-HBA).
基金supported in part by National Natural Science Foundation of China under Grant 62201087,Grant 62525101,in part by the National Key R&D Program of China under Grant 2023YFB2904803in part by the Guangdong Major Project of Basic and Applied Basic Research under Grant 2023B0303000001+1 种基金in part by the Natural Science Foundation of Beijing-Xiaomi Innovation Joint Foundation under Grant L243002in part by the Beijing University of Posts and Telecommunications-China Mobile Research Institute Joint Institute.
文摘As the commercialization of the fifth gen-eration communication(5G)is sped up,its system testing scheme is vital for the successful deployment of 5G.Especially,5G relies on the scale-increased multiple-input-multiple output(MIMO)technique to improve its capacity and coverage.Thus,testing new functions of the 5G MIMO system accurately and ef-ficiently,including beamforming(beam-tracking with movement)and multiple-user(MU)multiplexing,is a challenging task.This paper tries to construct a lab-oratorial hardware and conduct equipment-controlled field testing.Firstly,the testing scheme is presented,which is composed of the framework,the channel models and the validation methods.Then,the channel model principles are explained in detail due to its di-rect influence on the testing accuracy.Specifically,we utilize the spatial consistency and the multi-link cor-relation properties to emulate the high-speed dynamic time-varying(HDT)and the multiple-cell(MC)-MU-MIMO channels.Finally,the above testing scheme is verified in a Shanghai 5G field experiment with the practical commercial equipment and the channel em-ulator.The results show that the 5G new functions are tested accurately and efficiently by switching the channel emulation configurations.
基金Natural Science Foundation of China(Grant Nos.32471815 and 32401528)Natural Science Foundation of Jiangsu Province of China(Grant Nos.BK20241745 and BK20240294).
文摘With the increasing consumption of non renewable resources such as oil,the traditional polymer manufacturing industry that relies on fossil resources is facing unprecedented challenges.The design,synthesis,and recycling of renewable and environmentally friendly bio-based polymers as alternatives to petroleum based polymers have become hot topics in research and industrial fields.Biomass has been used as a raw material to design and synthesize closed-loop recyclable polymers,which is of great significance in addressing the waste of resources and negative impact on the environment in the traditional polymer preparation process.This review summarized recent advances in the design,synthesis,and properties of closed-loop recyclable bio-based polymers,focusing on the sustainability and recyclability of bio-based materials,followed by a brief discussion of the potential applications of closed-loop recyclable bio-based polymers in emerging applications such as 3D printing and friction electric nanogenerators.In addition,perspectives and recommendations for future research on closedloop recyclable bio-based polymers were presented.
基金supported by National Science and Technology Major Project of China(Project Number:2024ZD1300100)Fundamental Research Funds for the central universities(2024RC02)+1 种基金National Natural Science Foundation of China(62401077,62321001)Beijing Municipal Natural Science Foundation(L232003)。
文摘With the rapid growth of the low-altitude economy,the demand for typical low-altitude ap-plications has accelerated the advancement of inte-grated sensing and communications(ISAC)networks.This paper begins by analyzing representative ap-plication scenarios to clarify the core requirements of the low-altitude economy for modern ISAC net-works.By investigating the distinctive characteris-tics of ISAC networks in low-altitude environments,it presents a comprehensive analysis of key challenges and identifies four major issues:challenges in pre-cise target detection,interference management,in-consistent sensing and communication coverage,and the complexity of air-ground coordination and han-dover.Based on fundamental theories and principles,the paper proposes corresponding solutions,encom-passing advanced technologies for precise target de-tection and recognition,high-reliability networked de-tection,robust interference management,and seamless air-ground collaboration.These solutions aim to es-tablish a solid foundation for the future development of intelligent low-altitude networks and ensure effec-tive support for emerging applications.
基金supported by the National Natural Science Foundation of China(No.41975156).
文摘Tyrosine residues in proteins can be nitrated to form 3-nitrotyrosine(3-NT)under the influence of ozone(O_(3))and nitrogen dioxide(NO_(2))in the air,which may introduce health impacts.A selective and sensitive enzyme-linked-immunoassay(ELISA)method was developed to determine 3-NT in modified model protein(bovine serum albumin,BSA)and ambient aerosol samples.The nitration degrees(NDs)of BSA in the exposure experiments with different durations were detected by both the ELISA and spectrophotometric methods(i.e.,ND_(ELISA) and ND_(SEC-PDA)),which show good coincidence.The kinetic investigation by both ΔND_(ELISA) and ΔND_(SEC-PDA) in the exposure experiments shows that the rate coefficients(k)of the pseudo-first-order kinetic rate reactions of protein nitration were comparable.These results indicate that direct detection of 3-NT by the ELISA method can be applied for laboratory exposure samples analysis for kinetic studies.Based on the selective detection of 3-NT,ND_(ELISA) provides a promising measure for the assessment of ND in model proteins.3-NT was alsomeasured in PM_(2.5) samples in summer in Guangzhou,southern China,ranging from 10.1 to 404 pg/m^(3),providing clear evidence of protein nitration in ambient aerosols.We further proposed that 3-NT/protein can be used as a proxy to evaluate protein nitration in ambient aerosols.A significant correlationwas observed between 3-NT/protein and O_(3),confirming the crucial role of O_(3) in protein nitration.Our results show that the direct detection of 3-NT by the ELISA method can be more widely applied in the laboratory and field-based studies for understanding the mechanisms of protein nitration.
基金supported by the National Key R&D Program of China(No.2023YFB2904803)the Beijing Natural Science Foundation(L243002),the National Natural Science Foundation of China(No.62341128)+2 种基金the Guangdong Major Project of Basic and Applied Basic Research(No.2023B0303000001)the National Natural Science Foundation of China(No.62201086)Beijing University of Posts and Telecommunications-China Mobile Research Institute Joint Innovation Center.
文摘Extremely large-scale multiple-input multiple-output(XL-MIMO)is regarded as a promis-ing technology for next-generation communication systems.However,this will expand the near-field(NF)range,rendering more users more likely to be located in the NF region.In this paper,we aim to answer two questions:What are the new characteristics of the NF channel?Is it necessary to develop new transciver techniques to maintain system performance within the NF region?To this end,we first review current NF channel models and analyze the differences between the existing 3GPP TR 38.901 channel model and the NF channel model,including the spherical wavefront and spatially non-stationarity.Then,we provide ex-amples on how these differences affect the XL-MIMO system performance in terms of beamforming gain and achievable rate.Simulation results demonstrate that,when using far-field(FF)technique under the NF channel,the maximum normalized beam gain loss is less than 3 dB for most users in the NF region de-fined by Rayleigh distance.Moreover,the achievable rate loss of beam training is less than 3%compared to that realized by NF technique.Finally,we demonstrate the necessity of employing NF transceiver techniques based on simulation results.
基金Supported by National Natural Science Foundation of China(Grant Nos.52375447,52305477 and 52105457)the Shandong Provincial Natural Science Foundation of China(Grant Nos.ZR2023QE057,ZR2024QE100 and ZR2024ME255)+2 种基金Qingdao Municipal Science and Technology Planning Park Cultivation Plan(Grant No.23-1-5-yqpy-17-qy)Shandong Provincial Science and Technology SMEs Innovation Capacity Improvement Project(Grant No.2022TSGC1115)the Special Fund of Taishan Scholars Project。
文摘Intelligent manufacturing(IM),a driving force behind the fourth industrial revolution,is reshaping the manufacturing sector by enhancing productivity,efficiency,and sustainability.Despite the rapid technological advancements in IM,comprehensive bibliometric reviews remain limited.This article systematically reviews the latest research in IM,addressing emerging hotspots,key technologies,and their applications across the entire product manufacturing cycle.Bibliometric analysis is employed to identify research trends visualize publication volume,collaboration patterns,research domains,co-citations,and emerging areas of interest.The article then examines key technologies supporting IM,including sensors,the Internet of Things(IoT),big data analytics,cloud computing,artificial intelligence(AI),digital twins,and virtual reality(VR)/augmented reality(AR).Furthermore,it explores the application of these technologies throughout the manufacturing cycle-from intelligent reliability design,material transportation and tracking,to intelligent planning and scheduling,machining and fabrication,monitoring and maintenance,quality inspection and control,warehousing and management,and sustainable green manufacturing—through specific case studies.Lastly,the article discusses future research directions,highlighting the increasing global market and the need for enhanced interdisciplinary collaboration,technological integration,computing power upgrades,and attention to security and privacy in IM.This study provides valuable insights for scholars and serves as a guide for future research and strategic investment decisions,offering a comprehensive view of the IM field.
基金supported by the National Natural Science Foundation of China(No.22064014)the Science and Technology Development Plan Project of Lanzhou(No.2021–1-146)+2 种基金the Science and Technology Project of Gansu Province(Nos.21YF5FA071,21JR7RA538)the Industrial Support Programme for Higher Education Institutions Project(Nos.2023CYZC-69,2024CYCZ-05)the 2023 Gansu Provincial Key Talent Project(No.2023RCXM26)。
文摘The traditional nanozymes-based ratiometric fluorescence sensing platforms usually necessitate the supplementary addition of fluorescent probes,therefore greatly restricting its convenient and broad application.In this study,a highly sensitive and selective ratiometric fluorescence platform for alkaline phosphatase(ALP)detection was established,only employing Prussian blue(PB)nanozymes and a commercially available chromogen of o-phenylenediamine(OPD).PB nanozymes with remarkable peroxidaselike(POD-like)activity can effectively catalyze OPD chromogen to yield 2,3-diaminophenazine(OPDox)with an intense yellow fluorescence at 573 nm emission peak.Target ALP can facilitate ascorbic acid 2-phosphate(AAP)dephosphorylation to generate phosphate and ascorbic acid(AA).Significantly,both these two resultant hydrolysis products could effectively decrease the OPDox generation via a dualpath based inhibition on the PB nanozymes POD-like activity.On the other hand,the generated dehydroascorbic acid(DHAA)from AA oxidation would exclusively react with OPD chromogen to yield3-(dihydroxyethyl)furo[3,4-b]quinoxaline-1-one(DFQ)with a strong blue fluorescent signal at 434nm,which further providing a significant enhancement on the sensing selectivity of ALP detection.As a result,an increased yellow fluorescence of OPDox and decreased blue fluorescence of DFQ could be clearly observed with different ALP addition.A robust linear relationship between the fluorescence ratio of F_(434)/F_(573)and ALP activity ranging from 0.25U/L to 6U/L was obtained,with a low detection limit of 0.112 U/L.This proposed method demonstrates high sensitivity,excellent selectivity,cost-effectiveness,and operational simplicity,yet enabling an effective detection of ALP levels in human serum.
基金financially supported by the National Natural Science Foundation of China(No.51962027,and 52262039)the Fundamental Research Funds for Inner Mongolia University of Science&Technology(No.2024QNJS071,2023QNJS052 and 2024QNJS064)+2 种基金the Program for Young Talents of Science and Technology in Universities of Inner Mongolia Autonomous Region(No.NJYT24002)the Central Guidance Fund for Local Scientific and Technological Development(2024ZY0012)the Ordos Higher Education Institutions Scientific Research Innovation Project(KYLJ25Z004)。
文摘The octahedral tunnel-like three-dimensional(3D)structure of V_(2)O_(3)enables fast metal ion(de)intercalation and high capacity in aqueous zinc-ion batteries(ZIBs),but suffers from phase transition-induced structural degradation and capacity fading.Herein,we demonstrate that the undesirable phase transition of V_(2)O_(3)can be effectively suppressed through a new La^(3+)doping strategy and its implementation as a robust ZIBs cathode.The introduced La^(3+)ions not only can increase cell volume and expand ion channels of V_(2)O_(3)but also offer plentiful Zn^(2+)storage sites and promote the transport of Zn^(2+)ions and electrons.In particular,the doping of La^(3+)maintains the octahedral tunnel structure of V_(2)O_(3)and prevents its phase transition during(dis)charge,which improves the cycle stability of the V_(2)O_(3)cathode in ZIBs.By virtue of the above favorable factors,La-doped V_(2)O_(3)electrode presents an impressive discharge capacity of632.1 m Ah g^(-1)at 0.1 A g^(-1)after 100 cycles with a capacity retention up to 93.1%.Even at 10 A g^(-1),its discharge capacity remains at 342.7 mAh g^(-1)after 1000 cycles with a capacity attenuation of solely0.0069%per cycle.This work establishes rare-earth cation doping as a universal paradigm to reconcile structural stability and multi-electron redox activity in high-capacity battery electrodes.
文摘In this work,we proposed a strategy for the hydrolysis of native corn starch after the treatment of corn starch in an ionic liquid aqueous solution,and it is an awfully“green”and simple means to obtain starch with low molecular weight and amorphous state.X-ray diffraction results revealed that the natural starch crystalline region was largely disrupted by ionic liquid owing to the broken intermolecular and intramolecular hydrogen bonds.After hydrolysis,the morphology of starch changed from particles of native corn starch into little pieces,and their molecular weight could be effectively regulated during the hydrolysis process,and also the hydrolyzed starch samples exhibited decreased thermal stability with the extension of hydrolysis time.This work would counsel as a powerful tool for the development of native starch in realistic applications.
基金financially supported by the National Natural Science Foundation of China(Nos.22272118,22172111,and 22309134)the Science and Technology Commission of Shanghai Municipality,China(Nos.22ZR1464100,20ZR1460300,and 19DZ2271500)+2 种基金the China Postdoctoral Science Foundation(2022M712402),the Shanghai Rising-Star Program(23YF1449200)the Zhejiang Provincial Science and Technology Project(2022C01182)the Fundamental Research Funds for the Central Universities(2023-3-YB-07)。
文摘Carbon superstructures with multiscale hierarchies and functional attributes represent an appealing cathode candidate for zinc hybrid capacitors,but their tailor-made design to optimize the capacitive activity remains a confusing topic.Here we develop a hydrogen-bond-oriented interfacial super-assembly strategy to custom-tailor nanosheet-intertwined spherical carbon superstructures(SCSs)for Zn-ion storage with double-high capacitive activity and durability.Tetrachlorobenzoquinone(H-bond acceptor)and dimethylbenzidine(H-bond donator)can interact to form organic nanosheet modules,which are sequentially assembled,orientally compacted and densified into well-orchestrated superstructures through multiple H-bonds(N-H···O).Featured with rich surface-active heterodiatomic motifs,more exposed nanoporous channels,and successive charge migration paths,SCSs cathode promises high accessibility of built-in zincophilic sites and rapid ion diffusion with low energy barriers(3.3Ωs-0.5).Consequently,the assembled Zn||SCSs capacitor harvests all-round improvement in Zn-ion storage metrics,including high energy density(166 Wh kg-1),high-rate performance(172 m Ah g^(-1)at 20 A g^(-1)),and long-lasting cycling lifespan(95.5%capacity retention after 500,000 cycles).An opposite chargecarrier storage mechanism is rationalized for SCSs cathode to maximize spatial capacitive charge storage,involving high-kinetics physical Zn^(2+)/CF_(3)SO_(3)-adsorption and chemical Zn^(2+)redox with carbonyl/pyridine groups.This work gives insights into H-bond-guided interfacial superassembly design of superstructural carbons toward advanced energy storage.
文摘A detailed investigation was carried out to understand how the variations in configurations of the spiroannulated 6-6-6-5-5 pentacyclic diastereoisomers,the key intermediates for the synthesis of two C30 terpene quinonemethides and their stereoisomers,impact the reactivity of cyclopropanation.The configurations at C9,C8,and C14 for all four pentacyclic diastereoisomers involved in the diastereoisomeric mixture were determined through a combination of suitable chemical derivatization and multiple NMR spectroscopic analyses.Based on the defined configuration,the 3D structures of these diastereoisomers were optimized by density functional theory(DFT)calculation.These investigations provide reasonable supports,mainly from the steric considerations,for understanding why different diastereoisomers exhibit markedly different reactivity,as well as regio-and stereo-selectivity for cyclopropanation.In addition,the mechanism for the construction of the spiroannulated 6-6-6-5-5 pentacyclic scaffold via intramolecular Michael/aldol cascade was also investigated by deuterium labeling experiments.
基金supported by the Natural Science Foundation of China Grant No.52272289 and 5240223,and JSPS(Japan Society for the Promotion of Science)of Grant No.22K19088,23H00313,24H02202,and 24H02205。
文摘NiFe-layered double hydroxides(NiFe-LDHs)are among the most promising earth-abundant electrocatalysts for the oxygen evolution reaction(OER)in alkaline media.However,their practical application is hindered by intrinsic activity limitations and poor stability,primarily due to the asymmetric adsorption of oxygen intermediates.To overcome this,the binding strength must be synergistically tuned to a moderate level to optimize catalytic performance.Here,we engineered NiFeCoCr LDH through Co doping to enhance electrical conductivity and controlled Cr leaching to introduce cationic vacancies for modulating intermediate binding strength in NiFe LDH.X-ray absorption near-edge structure and extended X-ray absorption fine structure analyses reveal that NiFe-LDH with Co doping and Cr vacancies modulates the Ni oxidation state and local coordination environment,leading to a balanced electronic structure and enhanced structural complexity around the Ni sites.Additionally,these vacancies can trap OH^(-)/H_(2)O species,which can serve as a reservoir for OH^(-) transfer,facilitating the rapid formation of OER intermediates and enhancing catalytic performance at high current densities.As a result,V_(Cr)-NiFeCo LDH achieves 1.6 A cm^(-2)current density at 1.7 V vs.RHE while maintaining stable operation for over 1000 h at 500 mA cm^(-2).Density functional theory(DFT)calculations validate the synergistic effects of Co doping and Cr-induced vacancies on intermediate binding energies and improved OER kinetics.Overall,this work presents a rational design strategy to simultaneously enhance the activity and durability of NiFe-based OER catalysts for their application in high-performance alkaline water electrolysis.
基金supported by the National Natural Science Foundation of China(No.62267005)the Chinese Guangxi Natural Science Foundation(No.2023GXNSFAA026493)+1 种基金Guangxi Collaborative Innovation Center ofMulti-Source Information Integration and Intelligent ProcessingGuangxi Academy of Artificial Intelligence.
文摘The rapid development of information technology and accelerated digitalization have led to an explosive growth of data across various fields.As a key technology for knowledge representation and sharing,knowledge graphs play a crucial role by constructing structured networks of relationships among entities.However,data sparsity and numerous unexplored implicit relations result in the widespread incompleteness of knowledge graphs.In static knowledge graph completion,most existing methods rely on linear operations or simple interaction mechanisms for triple encoding,making it difficult to fully capture the deep semantic associations between entities and relations.Moreover,many methods focus only on the local information of individual triples,ignoring the rich semantic dependencies embedded in the neighboring nodes of entities within the graph structure,which leads to incomplete embedding representations.To address these challenges,we propose Two-Stage Mixer Embedding(TSMixerE),a static knowledge graph completion method based on entity context.In the unit semantic extraction stage,TSMixerE leveragesmulti-scale circular convolution to capture local features atmultiple granularities,enhancing the flexibility and robustness of feature interactions.A channel attention mechanism amplifies key channel responses to suppress noise and irrelevant information,thereby improving the discriminative power and semantic depth of feature representations.For contextual information fusion,a multi-layer self-attentionmechanism enables deep interactions among contextual cues,effectively integrating local details with global context.Simultaneously,type embeddings clarify the semantic identities and roles of each component,enhancing the model’s sensitivity and fusion capabilities for diverse information sources.Furthermore,TSMixerE constructs contextual unit sequences for entities,fully exploring neighborhood information within the graph structure to model complex semantic dependencies,thus improving the completeness and generalization of embedding representations.
基金Supported by National Modern Agricultural Industry Technology System Sichuan Pig Innovation Team(SCCXTD-2026-8)Sichuan Science and Technology Program(2025ZYD0049)"Challenge and Leadership"Project for Key Core Technologies of Sui Ning in Sichuan(2025SNKBZ19).
文摘Sichuan sausages with moisture contents of 40%,45%,50%,and 60% were stored at-18℃for durations of 0,2,4,6,and 8 weeks to evaluate the effect of moisture content on the quality attributes of Sichuan sausages during frozen storage.Product indicators including pH,colour,thiobarbituric acid reactive substances(TBARS),total volatile basic nitrogen(TVB-N),texture,electronic nose(E-nose)response,and water-holding capacity(thawing and cooking losses)were determined.The results indicated that as storage time increased,water retention in Sichuan sausages with different moisture contents decreased,while the degree of protein and lipid oxidation increased.This led to an increase in pH value,a colour shift from red-bright to grey-brown,and a deterioration in palatability.Among the samples,sausages with 50% moisture content exhibited the lowest thawing and cooking losses,indicating superior water-holding capacity.After 8 weeks of storage,TBARS and TVB-N values for the 50% moisture group were 19.5%and 2.5%lower,respectively,than those of the 40%and 45%moisture groups,indicating a reduced degree of oxidation.Furthermore,Sichuan sausage with 50%moisture content demonstrated an appropriate pH and colour difference,along with excellent texture and flavour,as evidenced by its higher toughness and satisfactory hardness.In conclusion,Sichuan sausage with 50% moisture content demonstrated the highest overall quality under frozen storage conditions.
基金financially supported by the National Natural Science Foundation of China(Nos.52130307 and 52121002).
文摘Polyolefins with intrinsic antimicrobial properties have attracted significant attention.In this study,various ion-functionalized polyolefins were successfully constructed by incorporating iodine-containing comonomers into a polypropylene backbone,followed by post-functionalization strategies that utilized the conversion reactions of pre-introduced iodine groups.The introduction of ionic groups induced notable changes in both the thermal properties and the melt rheological behavior of the material.The dual crosslinking mechanism based on ionic interactions and polypropylene crystallization significantly enhanced the mechanical strength of the material.In addition,imidazolium-based ionomers exhibit highly effective antimicrobial properties against Gram-negative Escherichia coli and Gram-positive Staphylococcus aureus.Specifically,the P5-CCl_(3)CO_(2)^(−)sample achieved a sterilization rate of 99.99%against both bacteria and maintained a high bactericidal efficacy of above 90%,even after continuous supplementation with fresh bacterial solutions for 15 days.Consequently,this polypropylene-based ionomer,which combines excellent mechanical strength with outstanding antimicrobial performance,demonstrates substantial application potential in children’s toys,food packaging,and medicine.
基金Supported by Research and Transformation Application of Capital Clinical Diagnosis and Treatment Technology by Beijing Municipal Commission of Science and Technology(No.Z201100005520043).
文摘AIM:To investigate the association between functionaloutcomes and postoperative patient satisfaction 5y aftersmall incision lenticule extraction(SMILE)and femtosecondlaser-assisted in situ keratomileusis(FS-LASIK).METHODS:This is a cross-sectional study.Thepatients underwent basic ophthalmic examinations,axiallength measurement,wide-field fundus photography,andaccommodation function testing.Behavioral habits datawere collected using a self-administered questionnaire,andvisual symptoms were assessed with the Quality of Vision(QoV)questionnaire.Postoperative satisfaction was alsorecorded.RESULTS:Totally 410 subjects[820 eyes,160males(39.02%)and 250 females(60.98%)]who hadundergone SMILE or FS-LASIK 5y ago were enrolled.Themean(standard deviation,SD)age of all patients was29.83y(6.69).The mean(SD)preoperative manifest SEwas-5.80(2.04)diopters(D;range:-0.88 to-13.75).Patient satisfaction at 5y after undergoing SMILE or FSLASIKwas 91.70%.Patients were categorized into twogroups:dissatisfied group and satisfied group.Significantdifferences were observed between the two groups in termsof age(P=0.012),sex(P=0.021),preoperative degreeof myopia(P=0.049),postoperative visual symptoms(frequency,P=0.043;severity,P<0.001;bothersome,P=0.018),difficulty driving at night(P=0.001),andaccommodative amplitude(AMP,P=0.020).Multivariateanalysis confirmed that female sex(P=0.024),severityof visual symptoms(P=0.009),and difficulty driving atnight(P=0.006)were significantly associated with lowersatisfaction.The dissatisfied group showed higher rates ofstarbursts,double or multiple images,and high myopia,but lower age.The frequency,severity,and bothersome ofdistortion exhibited decreased with increasing age.CONCLUSION:Patient satisfaction 5y after SMILEand FS-LASIK is high and stable.Difficulty driving at night,sex,and severity of visual symptoms are important factorsinfluencing patient satisfaction.Special attention should bepaid to younger highly myopic female patients,particularlythose with starbursts and double or multiple images.It is crucial to monitor postoperative visual outcomesand provide patients with comprehensive preoperativecounseling to enhance long-term satisfaction.
基金supported by the National Natural Science Foundation of China(Grant No.62106092)the Natural Science Foundation of Fujian Province(Grant Nos.2024J01822,2025J01981)the Natural Science Foundation of Zhangzhou City(Grant No.ZZ2024J28).
文摘Path planning for Unmanned Aerial Vehicles(UAVs)in complex environments presents several challenges.Traditional algorithms often struggle with the complexity of high-dimensional search spaces,leading to inefficiencies.Additionally,the non-linear nature of cost functions can cause algorithms to become trapped in local optima.Furthermore,there is often a lack of adequate consideration for real-world constraints,for example,due to the necessity for obstacle avoidance or because of the restrictions of flight safety.To address the aforementioned issues,this paper proposes a dynamic weighted spherical particle swarm optimization(DW-SPSO)algorithm.The algorithm adopts a dual Sigmoid-based adaptive weight adjustment mechanism for balancing global exploration and local exploitation,as well as a lens-based opposition learning one to improve search flexibility and solution diversity.Simulation experiments on real digital elevation models demonstrate that DW-SPSO significantly outperforms recent state-of-the-art particle swarm optimization(PSO)variants in terms of path safety,smoothness,and convergence speed.The performance superiority is statistically validated by the Wilcoxon signed-rank test.The results confirm the algorithm’s effectiveness in generating high-quality UAV paths under diverse threat conditions,offering a robust solution for autonomous navigation systems.
