MXene-based smart contact lenses demonstrate a cutting-edge advancement in wearable ophthalmic technology,combining real-time biosensing,therapeutic capabilities,and user comfort in a single platform.These devices tak...MXene-based smart contact lenses demonstrate a cutting-edge advancement in wearable ophthalmic technology,combining real-time biosensing,therapeutic capabilities,and user comfort in a single platform.These devices take the advantage of the exceptional electrical conductivity,mechanical flexibility,and biocompatibility of two-dimensional MXenes to enable noninvasive,tear-based monitoring of key physiological markers such as intraocular pressure and glucose levels.Recent developments focus on the integration of transparent MXene films into the conventional lens materials,allowing multifunctional performance including photothermal therapy,antimicrobial and anti-inflammation protection,and dehydration resistance.These innovations offer promising strategies for ocular disease management and eye protection.In addition to their multifunctionality,improvements in MXene synthesis and device engineering have enhanced the stability,transparency,and wearability of these lenses.Despite these advances,challenges remain in long-term biostability,scalable production,and integration with wireless communication systems.This review summarizes the current progress,key challenges,and future directions of MXene-based smart contact lenses,highlighting their transformative potential in next-generation digital healthcare and ophthalmic care.展开更多
The impact of earthquakes in urban centers prone to disastrous earthquakes necessitates the analysis of associ- ated risk for rational formulation of contingency plans and mitigation strategies.In urban centers,the se...The impact of earthquakes in urban centers prone to disastrous earthquakes necessitates the analysis of associ- ated risk for rational formulation of contingency plans and mitigation strategies.In urban centers,the seismic risk is best quantified and portrayed through the preparation of'Earthquake Damage and Loss Scenarios.'The components of such scenarios are the assessment of the hazard,inventories and the vulnerabilities of elements at risk.For the development of the earthquake risk scenario in Istanbul,two independent approaches,one based on intensities and the second on spectral displacements,are utilized.This paper will present the important features of a comprehensive study,highlight the method- ology,discuss the results and provide insights to future developments.展开更多
Since the 18th century, the irritating but also fascinating scenes of urbanity--a complex phenomenon with cultural, social, political, economic, temporal, spatial, functional, and formal dimensions--have been describe...Since the 18th century, the irritating but also fascinating scenes of urbanity--a complex phenomenon with cultural, social, political, economic, temporal, spatial, functional, and formal dimensions--have been described in literary works. Many seemingly opposite facts, such as individuality/society, freedom/loneliness/socialization, anonymity/strangeness/identity/belonging, diversity/chaos/segregation, indifferent city-dweller/initiative citizenship, have been revealed through literary works, travel and utopian writing, urban theories, scientific studies, manifestos, and newspaper articles. On the one hand, there are those who advocate a life outside the city because they consider the problems produced by the city and the phenomenon of density which they perceive merely in quantitative terms, as unsolvable problems. On the other hand, there are those who see the production of loose urban fabric as a solution or those who accept the （seemingly） opposite facts of urbanity as positive values and therefore support city life. All of these ideas are still as actual today as they were in the past. We are often unable to use our citizen rights to the city, to encounter different classes （social/etlmic/religious）, to experience heterogeneity as an aspect inherent in city life and in the route of our daily life--following the orders of the capitalist system mainly organized around work--and we are often drawn into the same districts on the same paths. Our perception of our urban environments may get monotonous and shallow, but the irritating yet fascinating features of the first big cities still exist and may be grasped and brought into consciousness. Throughout their architectural education, especially in urban design studios, students can be encouraged to investigate the rhythm of their daily life, the conditions of their urban environments, and discovering the city as an intellectual and sensual programme, so that the phenomenon of urbanity can be grasped not just on formal, but on various other dimensions as well. This study focuses on the process and outcomes of two urban studios located in Taksim Square and along the shores of the Golden Horn in Istanhul. Taking the multidimensional content of urbanity into account, acquired theoretically through literary works and studies on urban planning and its history, the main aim of these studios has been the phenomenological understanding of the dynamic content of urbanity by the students. Through creative analysis of permanent/temporary spaces engendered by the diversity of user profiles and actions discovered on phenomenological excursions, students examine the qualitative values of density and global and local dynamics. We believe that designing spaces as ＂prototypes＂ helps highlight the multidimensional content of urbanity. The present study aims not only to highlight the multidimensional content of urbanity, but also to encourage its discussion in architectural design education and to emphasize the positive contribution of theoretical readings and phenomenological studies to urban design studios. The present study also aims to emphasize the beneficial correlation of global and local dynamics as the two faces of urbanity; important more than ever for the big cities of the 21 st century if we advocate for a vivid and resilient city life and citizens.展开更多
With coming in force of The Law of Transformation of Areas at Disaster Risks numbered 16.5.2012/6306 by Ministry of Environment and Urbanization,the concept of urban transformation has entered to our life in Turkey.Ge...With coming in force of The Law of Transformation of Areas at Disaster Risks numbered 16.5.2012/6306 by Ministry of Environment and Urbanization,the concept of urban transformation has entered to our life in Turkey.Gentrification as one of the forms of urban transformation brought the existence of liberated zones produced by neo-liberal mentality.Sulukule area(Neslisah Sultan settlement)which is subject to research is counted among“the areas to be renewed and to be put under preservation”by numbered 2006/10299 decision of Council of Ministers.Due to the shortage of lands in the city,it is observed especially in 1980s that the families in high-income group have preferred to live in horizontally expending villa towns far from the center.While these residential areas are deepening the distance from the center in time,the pressure of housing demand of middle-income people and rent circles who are not planning to leave the city center caused to have an eye on these areas which are residential areas of mostly low-income people and appeared in certain regions as they are established without infrastructure and healthy conditions.With this law,the transformation has started in the areas such as Fikirtepe,Dolapdere,Esenler,and Banks of Halic(Golden Horn)where structural life is completed,and floor area ratio has been raised to 4.0 from 2.07.Vertical housing is stimulated by adding the street between the parcels to the blocks,it has been tried to prevent the victimization of local people to unearned income.There are some quarters that,under the name of gentrification,Romany citizens who passed to permanent settlement from nomadic culture at the Ottoman era,and who are engaged in activities such as handicraft,adornments,shoe making,weaving beside the show business at Fatih Sulukule district are convicted to lodge in the houses built in suburban if they have title deed,and in jerry-built tents if they don’t have deed.Chamber of Architects,Chamber of City Planners Istanbul Branch and Roma Culture Development and Solidarity Association filed“nullity suit”and“stay of execution”.Despite the continuing judicial process,the demolition started in 2009,and starting the constructing the villas in 2010 breaking the resistance of Romany citizens,the area was victimized to rent.展开更多
BACKGROUND Obsessive-compulsive disorder(OCD)is a heterogeneous disease in many respects and exhibits this diversity in terms of phenomenology.It also displays several different characteristics in children compared to...BACKGROUND Obsessive-compulsive disorder(OCD)is a heterogeneous disease in many respects and exhibits this diversity in terms of phenomenology.It also displays several different characteristics in children compared to adults.AIM To describe the socio-demographic and phenomenological features of children with OCD and to investigate the impact of these features on response to pharmacotherapy.METHODS This retrospective study was carried out with 150 children and adolescents who had been diagnosed with OCD between 2014 and 2018.Data was collected by examining the files of the patients with diagnosis of OCD and similar disorders from the hospital database.Yale-Brown Obsessive-Compulsive Scale for Children was used for the assessment of obsession-compulsion subtypes.The Clinical Global Impression(CGI)scale was used to evaluate the severity of the disease(CGI-S)and global improvement(CGI-I).The predictors of treatment response were evaluated using linear regression analysis.The level of significance for all statistic tests was set as P<0.05.RESULTS The sample was divided into prepubertal(44%)and adolescent(56%)age groups.The most prevalent obsessions were contamination and aggression obsessions,and the most frequent compulsions were washing and checking.While contamination was observed more commonly in the prepubertal age group,the religious obsession was seen more frequently in adolescents.Patients with aggression obsession presented a higher frequency of comorbid anxiety(P=0.022)and mood subgroups(P>0.05).A lower CGI-I score was linked to a lower CGI-S score(95%confidence interval 0.21-0.39,P<0.001)and the prepubertal age of admission(95%confidence interval 0.03-0.87,P=0.020).CONCLUSION The phenomenology of OCD shows differences depending on the age group and the comorbid psychiatric disorders.Earlier identification and treatment of OCD may help to prevent the impairment of the mental health of children and adolescents.展开更多
Restoration of historical buildings is important because they maintain cultural and historical continuity and transmit the cultural and social values from our precedents to future generations.Historical buildings need...Restoration of historical buildings is important because they maintain cultural and historical continuity and transmit the cultural and social values from our precedents to future generations.Historical buildings need to adapt themselves to a changing cultural,social,economic,and political context.In this paper refunctioning project of a historic Ottoman,warehouse is presented.The aim of the project is to re-gain this historical structure for public use by re-newing it to the modern comfort level and making the required functional changes.The main structural system of the warehouse consists of thick masonry stone walls.The idea in the proposed restoration project is to build a two-story steel structure inside the available volume of the warehouse.The columns of the new steel construction run parallel to the existing structural system of the historic building and are fixed at their base to the existing building foundation.Hence,there is no connection between the proposed steel structure walls and the existing masonry walls,and this will save the historic fabric of the warehouse.The project proposal shows the details of planned restoration stages,the process of programming the new interior space,construction materials,and lighting and ventilation solutions.Furthermore,in this project,two-and threedimensional computer drawings were used.Finally,the proposed parallel steel structure is able to regain the warehouse and renew it to be used as a modern housing and workshop.展开更多
Emerging evidence underscores the critical role of intestinal microbiota in postoperative recovery and long-term outcomes of gastrointestinal procedures.In this editorial,we comment on the retrospective study by Niu e...Emerging evidence underscores the critical role of intestinal microbiota in postoperative recovery and long-term outcomes of gastrointestinal procedures.In this editorial,we comment on the retrospective study by Niu et al,which highlights the beneficial impact of dietary fiber supplementation on gut microbiota restoration following endoscopic mucosa resection.The findings highlight the potential of fiber supplementation to modulate gut microbiota and support recovery following endoscopic mucosa resection.Nonetheless,we also emphasize the need for prospective,randomized studies to delineate the optimal type,dose,and duration of fiber supplementation.This research represents a significant step toward evidence-based nutritional interventions in minimally invasive gastrointestinal surgery and underscores the importance of microbiota-targeted therapies in personalized postoperative care.展开更多
Detection of Autism Spectrum Disorder(ASD)is a crucial area of research,representing a foundational aspect of psychological studies.The advancement of technology and the widespread adoption of machine learning methodo...Detection of Autism Spectrum Disorder(ASD)is a crucial area of research,representing a foundational aspect of psychological studies.The advancement of technology and the widespread adoption of machine learning methodologies have brought significant attention to this field in recent years.Interdisciplinary efforts have further propelled research into detection methods.Consequently,this study aims to contribute to both the fields of psychology and computer science.Specifically,the goal is to apply machine learning techniques to limited data for the detection of Autism Spectrum Disorder.This study is structured into two distinct phases:data preprocessing and classification.In the data preprocessing phase,four datasets—Toddler,Children,Adolescent,and Adult—were converted into numerical form,adjusted as necessary,and subsequently clustered.Clustering was performed using six different methods:Kmeans,agglomerative,DBSCAN(Density-Based Spatial Clustering of Applications with Noise),mean shift,spectral,and Birch.In the second phase,the clustered ASD data were classified.The model’s accuracy was assessed using 5-fold cross-validation to ensure robust evaluation.In total,ten distinct machine learning algorithms were employed.The findings indicate that all clustering methods demonstrated success with various classifiers.Notably,the K-means algorithm emerged as particularly effective,achieving consistent and significant results across all datasets.This study is expected to serve as a guide for improving ASD detection performance,even with minimal data availability.展开更多
Even if dissociation has various facets,it is clear that knowledge of dissociative psychosis and a dissociative schizophrenia-based viewpoint may provide new perspectives on mental disorders.Many researchers screening...Even if dissociation has various facets,it is clear that knowledge of dissociative psychosis and a dissociative schizophrenia-based viewpoint may provide new perspectives on mental disorders.Many researchers screening for comorbid symptoms of“childhood traumatic experiences”and“dissociation”,where specific characteristics are significant to the presence of psychosis and schizophrenia,may lead to an acceptable definition.In recent years,researchers have also reported crucial advances in the understanding of dissociative psychosis and dissociative schizophrenia.Although clinical studies in this area have been ongoing for a long time,research has not demonstrated that a clear and valid relationship exists between dissociation,childhood traumatic experiences,and schizophrenia or psychotic spectrum disorders.However,some results of statistical comparisons have supported the existence of the clinical manifestation known as dissociative psychosis and dissociative schizophrenia.Dissociation,childhood traumatic experiences,and positive psychotic symptoms may be a prominent part of dissociative psychosis and schizophrenia.The intense presence of negative symptoms may indicate classical schizophrenia.In research and clinical practice,researchers and clinicians may use psychometric tests to detect symptoms of dissociative psychosis.Psychotic persons with traumatic experiences likely benefit from treatment focused on trauma symptomatolgy.展开更多
Application of variable speed limits(VSL)is gradually increasingly implemented especially on highways.As a result of conducted studies and implementations,it is observed that the variable speed limits have reduced the...Application of variable speed limits(VSL)is gradually increasingly implemented especially on highways.As a result of conducted studies and implementations,it is observed that the variable speed limits have reduced the number of car accidents as well as proved positive results in terms of delays and environmental factors.Purpose of this study is to develop an algorithm for VSL application that is considered to be applied on Istanbul D100 highway and to assess the effects of application.Algorithm that is developed for VSL is a different VSL algorithm and compared with the constant speed system.According to obtained results,when the proposed system is compared to current system,it is observed that the number of delays and average stops are reduced%30 and%40 respectively and also emissions reduced at the rate of%12.展开更多
BACKGROUND Organ donation and transplantation are vital for saving lives,yet awareness remains limited.Health literacy,the ability to understand and use health information,and self-control,which influences decision-ma...BACKGROUND Organ donation and transplantation are vital for saving lives,yet awareness remains limited.Health literacy,the ability to understand and use health information,and self-control,which influences decision-making,are crucial factors in promoting awareness.Understanding their relationship can guide efforts to increase participation in organ donation.AIM To investigate the effect of health literacy on organ donation and transplantation awareness,with self-control acting as a mediator,and to emphasize its importance.METHODS The study comprised 345 adults recruited from five different cities in Türkiye.The sample included 208 women(60.29%)and 137 men(39.71%).The age range of the sample group varies between 18 and 49(median age=24.13;SD=8.81).Selfreport data were collected including psychometric measures assessing organ donation and transplantation awareness,health literacy,and self-control.Reliability analysis,descriptive statistics,correlational analysis,and mediational analysis of the data were carried.RESULTS The analysis showed that health literacy was positively correlated with organ donation and transplantation awareness(r=0.340)and self-control(r=0.376).Self-control was positively related to organ donation and transplantation awareness(r=0.531).Mediating analysis supported a mediation model where health literacy was found to influence organ donation and transplantation awareness via self-control(bootstrap=0.158,95%confidence interval=0.105-0.215).CONCLUSION The results indicate that self-control mediates the positive relationship between health literacy and organ donation and transplantation awareness.Enhancing individuals’health literacy may therefore increase awareness of organ donation and transplantation through improvements in self-control.展开更多
In the Fatira(Abu Zawal)mine area,located in the northern Eastern Desert of Egypt,fieldwork and mineralogical analysis,integrated with machine learning techniques applied to Landsat-8 OLI,ASTER,and Sentinel-2 multi-sp...In the Fatira(Abu Zawal)mine area,located in the northern Eastern Desert of Egypt,fieldwork and mineralogical analysis,integrated with machine learning techniques applied to Landsat-8 OLI,ASTER,and Sentinel-2 multi-spectral imagery(MSI)data delineate gold-sulfide mineralization in altered rocks.Gold(Au)anomalies in hydrothermal breccias and quartz veins are associated with NE-oriented felsite dykes and silicified granitic rocks.Two main alteration types are identified:a pyrite-sericite-quartz and a sulfide-chlorite-carbonate assemblage,locally with dispersed free-milling Au specks.Dimensionality reduction techniques,including principal component analysis(PCA)and independent component analysis(ICA),enabled mapping of alteration types.Sentinel-2 PC125 composite images offered efficient lithological differentiation,while supervised classifications,i.e.,the support vector machine(SVM)of Landsat-8 yielded an accuracy of 88.55%and a Kappa value of 0.86.ASTER mineral indices contributed to map hydrothermal alteration mineral phases,including sericite,muscovite,kaolinite,and iron oxides.Results indicate that post-magmatic epigenetic hydrothermal activity significantly contributed to the Au-sulfide mineralization in the Fatira area,distinguishing it from the more prevalent orogenic gold deposits in the region.展开更多
This study investigates laminar convection in three regimes(forced convection,mixed convection,and natural convection)of a bi-nanofluid(Cu-Al_(2)O_(3)-water)/mono-nanofluid(Al_(2)O_(3)-water)inside a square enclosure ...This study investigates laminar convection in three regimes(forced convection,mixed convection,and natural convection)of a bi-nanofluid(Cu-Al_(2)O_(3)-water)/mono-nanofluid(Al_(2)O_(3)-water)inside a square enclosure of sliding vertical walls which are kept at cold temperature and moving up,down,or in opposite directions.The enclosure bottom is heated partially by a central heat source of various sizes while the horizontal walls are considered adiabatic.The thermal conductivity and dynamic viscosity are dependent on temperature and nanoparticle size.The conservation equations are implemented in the solver ANSYS R2(2020).The numerical predictions are successfully validated by comparison with data from the literature.Numerical simulations are carried out for various volume fractions of solid mono/hybrid-nanoparticles(0≤ϕ≤5%),Richardson numbers(0.001≤Ri≤10),and hot source lengths((1/5)H≤ε≤(4/5)H).Isothermal lines,streamlines,and average Nusselt numbers are analyzed.The thermal performance of nanofluids is compared to that of the base heat transfer fluid(water).Outcomes illustrate the flow characteristics significantly affected by the convection regime,hot source size,sidewall motion,and concentration of solid nanoparticles.In the case of sidewalls moving downward,using hybrid nanofluid(Cu-Al_(2)O_(3)-water)shows the highest heat transfer rate in the enclosure at Ri=1,ε=(4/5)H and volume fraction ofφ=5%where a significant increment(25.14%)of Nusselt number is obtained.展开更多
Delayed wound healing following radical gastrectomy remains an important yet underappreciated complication that prolongs hospitalization,increases costs,and undermines patient recovery.In An et al’s recent study,the ...Delayed wound healing following radical gastrectomy remains an important yet underappreciated complication that prolongs hospitalization,increases costs,and undermines patient recovery.In An et al’s recent study,the authors present a machine learning-based risk prediction approach using routinely available clinical and laboratory parameters.Among the evaluated algorithms,a decision tree model demonstrated excellent discrimination,achieving an area under the curve of 0.951 in the validation set and notably identifying all true cases of delayed wound healing at the Youden index threshold.The inclusion of variables such as drainage duration,preoperative white blood cell and neutrophil counts,alongside age and sex,highlights the pragmatic appeal of the model for early postoperative monitoring.Nevertheless,several aspects warrant critical reflection,including the reliance on a postoperative variable(drainage duration),internal validation only,and certain reporting inconsistencies.This letter underscores both the promise and the limitations of adopting interpretable machine learning models in perioperative care.We advocate for transparent reporting,external validation,and careful consideration of clinically actionable timepoints before integration into practice.Ultimately,this work represents a valuable step toward precision risk stratification in gastric cancer surgery,and sets the stage for multicenter,prospective evaluations.展开更多
This paper investigates the reliability of internal marine combustion engines using an integrated approach that combines Fault Tree Analysis(FTA)and Bayesian Networks(BN).FTA provides a structured,top-down method for ...This paper investigates the reliability of internal marine combustion engines using an integrated approach that combines Fault Tree Analysis(FTA)and Bayesian Networks(BN).FTA provides a structured,top-down method for identifying critical failure modes and their root causes,while BN introduces flexibility in probabilistic reasoning,enabling dynamic updates based on new evidence.This dual methodology overcomes the limitations of static FTA models,offering a comprehensive framework for system reliability analysis.Critical failures,including External Leakage(ELU),Failure to Start(FTS),and Overheating(OHE),were identified as key risks.By incorporating redundancy into high-risk components such as pumps and batteries,the likelihood of these failures was significantly reduced.For instance,redundant pumps reduced the probability of ELU by 31.88%,while additional batteries decreased the occurrence of FTS by 36.45%.The results underscore the practical benefits of combining FTA and BN for enhancing system reliability,particularly in maritime applications where operational safety and efficiency are critical.This research provides valuable insights for maintenance planning and highlights the importance of redundancy in critical systems,especially as the industry transitions toward more autonomous vessels.展开更多
Recently, important land use changes have occurred in the Black Sea coastal regions of istanbul due to urban growth and population increases. The objective of this study was to determine changes in land use in the Bla...Recently, important land use changes have occurred in the Black Sea coastal regions of istanbul due to urban growth and population increases. The objective of this study was to determine changes in land use in the Black Sea coastal regions of Jstanbul between 1987 and 2007. Landsat 30 m satellite images from 1987 and 2007 are used in the study. The study area is 1000 m in width from the coastline to the land and the study has been carried out using the controlled classification method to classify areas into residential, agricultural, forest, bare land, brush/grassland, and lake/pond land classes. Land use changes between 1987 and 2007 were analysed in detail. Residential areas of the Black Sea coastal regions of istanbul increased by 122% over the two decades. Also an increase of 55% in agriculture areas was observed, while there were decreases of 26% in forest areas and 15% in free land. A 21% increase in the area of brush and grassland took place. Furthermore 79% of the study area was covered by residential areas in 2007. It is probable that pressure on the Jstanbul coastal regions will continue due to migraton and rapid urbanization. Therefore, Istanbul＇s Black Sea coastal regions should be maintained using a sustainable coastal management plan.展开更多
Neoplastic proliferation of plasma cells is called plasma cell dyscrasias, and these neoplasms can present as a solitary neoplasm or multiple myeloma. Extramedullary plasmacytoma, in particular pancreatic plasmacytoma...Neoplastic proliferation of plasma cells is called plasma cell dyscrasias, and these neoplasms can present as a solitary neoplasm or multiple myeloma. Extramedullary plasmacytoma, in particular pancreatic plasmacytoma, is a rare manifestation of multiple myeloma. Although computerized tomography is useful for the diagnosis of extramedullary plasmacytoma, there are no specific radiologic markers that distinguish it from adenocarcinoma. Histological confirmation by biopsy is necessary for accurate diagnosis and management of the tumor. Endosonography is the most sensitive method for the diagnosis of pancreatic tumors, and the use of fine needle aspiration by endosonography is associated with a lower risk for malignant seeding and complications. Here, we report a case of pancreatic plasmacytoma in newly identified multiple myeloma as diagnosed by endosonography. Endosonography is a reliable and rapid method for the diagnosis of extramedullary plasmacytoma. Therefore, endosonographic fine needle aspiration should be the first choice for histological evaluation when pancreatic plasmacytoma is suspected. Ideally, the pathology would be performed at the same site as endosonographic biopsy.展开更多
AIM: To assess lung parenchymal changes in ankylosing spondylitis (AS) using high resolution computed tomography (HRCT). METHODS: We included 78 AS patients whose average age was 33.87 (18-56) years with a ratio of 53...AIM: To assess lung parenchymal changes in ankylosing spondylitis (AS) using high resolution computed tomography (HRCT). METHODS: We included 78 AS patients whose average age was 33.87 (18-56) years with a ratio of 53 males to 25 females who were followed up for 3.88 (1-22) years on average. neumonia and tuberculosis were excluded. In a detailed examination of lung HRCT findings, we investigated the presence of parenchymal micronodules,parenchymal bands, subpleural bands, interlobular and intralobular septal thickening, irregularity of interfaces,ground glass opacity, consolidation, mosaic pattern,bronchial wall thickening, bronchial dilatation, tracheal dilatation, pleural thickening, emphysema, thoracic cage asymmetry, honeycomb appearance, structural distortion, apical fibrosis and other additional findings.RESULTS: In detailed HRCT evaluations, lung parenchymal changes were found in 46 (59%) of all patients. We found parenchymal bands in 21 (27%) cases, interlobular septal thickening in 9 (12%), emphysema in 9 (12%), apical fibrosis in 8 (10%), ground-glass opacities in 7 (9%), parenchymal micronodules in 5 (6%), irregularity in interfaces in 3 (4%), bronchial dilatation in 3 (4%), mosaic pattern in 2 (3%), pleural thickening in 2 (3%), consolidation in 1 (1%), bronchial wall thick ening in 1 (1%) and a subpleural band in 1 (1%) case. Furthermore, we detected subsegmental atelectasis in 2 patients and a cavitary lesion in 1 patient. CONCLUSION: Our study had the highest number of AS cases of all previous studies in evaluating lung paren chymal changes. The rate of lung parenchymal changes was slightly lower than that reported in recent literature.展开更多
BACKGROUND Children diagnosed with autism spectrum disorder(ASD)may have great difficulties when their routines change,and this may affect the psychological wellbeing of their parents.For this reason,it is important t...BACKGROUND Children diagnosed with autism spectrum disorder(ASD)may have great difficulties when their routines change,and this may affect the psychological wellbeing of their parents.For this reason,it is important to examine studies that address the mental health of parents in order to adapt to the coronavirus disease 2019(COVID-19)pandemic.AIM To determine the mental health status of parents with children diagnosed with ASD in the COVID-19 pandemic.METHODS The study,which is a systematic review,was conducted between December 15,2020 and December 30,2020 by scanning articles in English.The Scopus,Science Direct,PubMed,Cochrane,Web of Science,and Google Scholar databases were used for scanning.The keywords COVID-19 AND(“autism”OR“autistic”OR“autism spectrum disorder”)AND parent AND(“mental health”OR“anxiety”OR“stress”)were used in the search process.The inclusion criteria in the study were findings regarding the mental health of parents with children diagnosed with ASD in the COVID-19 pandemic,addressing their anxiety and stress situations,being a research article,and accessing the full text of the article.RESULTS In the study,a total of 6389 articles were reached,and the full texts of 173 articles were evaluated for eligibility.After the articles excluded by the full-text search were eliminated,12 studies involving 7105 parents were included in the analysis.The findings obtained from the articles containing data on mental health in the COVID-19 pandemic of parents with children with autism spectrum disorder were discussed in three groups.These were findings on the experiences of parents with children with ASD in the COVID-19 pandemic regarding the areas where parents with children with ASD need support in the COVID-19 pandemic and methods of coping with the COVID-19 pandemic for parents with children with ASD.In the systematic review,it was determined that the anxiety and stress of the parents increased,they needed more support compared to the pre-pandemic period,and they had difficulty coping.CONCLUSION In this systematic review,it was concluded that the COVID-19 pandemic negatively affected the mental health of the parents of children with ASD.展开更多
Background:Thinning is a commonly used treatment in forest management which affects the tree root systems.The effects of thinning on element concentrations and seasonal change of roots were evaluated in adjacent oak(Q...Background:Thinning is a commonly used treatment in forest management which affects the tree root systems.The effects of thinning on element concentrations and seasonal change of roots were evaluated in adjacent oak(Quercus frainetto Ten.)and hornbeam(Carpinus betulus L.)stands according to the different root diameter classes.Method:Two replicated control and thinning plots(50m×50 m)were set for each species(hornbeam and oak).Thinning treatments(November 2010)reduced 50%of the basal area in both oak and hornbeam stands.Roots were assessed by seasonal collection over 2 years(from October 2010 to October 2012).The roots were then sorted into diameter classes of 0–2mm(fine roots),2–5mm(small roots)and>5mm(coarse roots).C,N,P,K,Ca,Na,Mg,S,Mn,Fe,Al,Zn,Pb,Ni,Cu and Cd were analyzed.Results:Except coarse roots,the highest root biomasses were determined in April-2011 in all plots.Fine-root biomass in oak was found significantly higher in control plots.In contrast to the oak,the fine-root biomass in the thinned hornbeam plots was higher than in the controls.The small-root biomass did not significantly differ between the thinned and the control plots in both oak and hornbeam stands.However,the coarse-root biomass showed significant differences between the control(1989 g∙m^(−2))and thinned plots(1060 g∙m^(−2))in oak,while no difference was detected in hornbeam.The concentrations of C,Al,Pb,Cd,Ni,Zn,Mn,Na,K,Mg and P in the fine roots of oak were significantly higher in the thinned plots.However,the concentration of Pb,Cd and Fe in the fine roots was significantly higher in the thinned plots of hornbeam.Significant differences were observed between the species for all elements in the fine roots except for C,N and P.In particular,elements in the fine roots tended to increase in July in the oak.In the hornbeam,all element concentrations in the fine roots(except C,N,and S)in the thinned plots showed a tendency to increase in April.The concentrations of Pb,Ni,Al,Fe,Cu,Ca,Na,K,Mg and P in the hornbeam control plots increased during the April 2011 period.Conclusion:The results indicated that thinning effects on temporal changes and concentrations of elements in the roots could be attributed to species-specific characteristics.展开更多
文摘MXene-based smart contact lenses demonstrate a cutting-edge advancement in wearable ophthalmic technology,combining real-time biosensing,therapeutic capabilities,and user comfort in a single platform.These devices take the advantage of the exceptional electrical conductivity,mechanical flexibility,and biocompatibility of two-dimensional MXenes to enable noninvasive,tear-based monitoring of key physiological markers such as intraocular pressure and glucose levels.Recent developments focus on the integration of transparent MXene films into the conventional lens materials,allowing multifunctional performance including photothermal therapy,antimicrobial and anti-inflammation protection,and dehydration resistance.These innovations offer promising strategies for ocular disease management and eye protection.In addition to their multifunctionality,improvements in MXene synthesis and device engineering have enhanced the stability,transparency,and wearability of these lenses.Despite these advances,challenges remain in long-term biostability,scalable production,and integration with wireless communication systems.This review summarizes the current progress,key challenges,and future directions of MXene-based smart contact lenses,highlighting their transformative potential in next-generation digital healthcare and ophthalmic care.
文摘The impact of earthquakes in urban centers prone to disastrous earthquakes necessitates the analysis of associ- ated risk for rational formulation of contingency plans and mitigation strategies.In urban centers,the seismic risk is best quantified and portrayed through the preparation of'Earthquake Damage and Loss Scenarios.'The components of such scenarios are the assessment of the hazard,inventories and the vulnerabilities of elements at risk.For the development of the earthquake risk scenario in Istanbul,two independent approaches,one based on intensities and the second on spectral displacements,are utilized.This paper will present the important features of a comprehensive study,highlight the method- ology,discuss the results and provide insights to future developments.
文摘Since the 18th century, the irritating but also fascinating scenes of urbanity--a complex phenomenon with cultural, social, political, economic, temporal, spatial, functional, and formal dimensions--have been described in literary works. Many seemingly opposite facts, such as individuality/society, freedom/loneliness/socialization, anonymity/strangeness/identity/belonging, diversity/chaos/segregation, indifferent city-dweller/initiative citizenship, have been revealed through literary works, travel and utopian writing, urban theories, scientific studies, manifestos, and newspaper articles. On the one hand, there are those who advocate a life outside the city because they consider the problems produced by the city and the phenomenon of density which they perceive merely in quantitative terms, as unsolvable problems. On the other hand, there are those who see the production of loose urban fabric as a solution or those who accept the （seemingly） opposite facts of urbanity as positive values and therefore support city life. All of these ideas are still as actual today as they were in the past. We are often unable to use our citizen rights to the city, to encounter different classes （social/etlmic/religious）, to experience heterogeneity as an aspect inherent in city life and in the route of our daily life--following the orders of the capitalist system mainly organized around work--and we are often drawn into the same districts on the same paths. Our perception of our urban environments may get monotonous and shallow, but the irritating yet fascinating features of the first big cities still exist and may be grasped and brought into consciousness. Throughout their architectural education, especially in urban design studios, students can be encouraged to investigate the rhythm of their daily life, the conditions of their urban environments, and discovering the city as an intellectual and sensual programme, so that the phenomenon of urbanity can be grasped not just on formal, but on various other dimensions as well. This study focuses on the process and outcomes of two urban studios located in Taksim Square and along the shores of the Golden Horn in Istanhul. Taking the multidimensional content of urbanity into account, acquired theoretically through literary works and studies on urban planning and its history, the main aim of these studios has been the phenomenological understanding of the dynamic content of urbanity by the students. Through creative analysis of permanent/temporary spaces engendered by the diversity of user profiles and actions discovered on phenomenological excursions, students examine the qualitative values of density and global and local dynamics. We believe that designing spaces as ＂prototypes＂ helps highlight the multidimensional content of urbanity. The present study aims not only to highlight the multidimensional content of urbanity, but also to encourage its discussion in architectural design education and to emphasize the positive contribution of theoretical readings and phenomenological studies to urban design studios. The present study also aims to emphasize the beneficial correlation of global and local dynamics as the two faces of urbanity; important more than ever for the big cities of the 21 st century if we advocate for a vivid and resilient city life and citizens.
文摘With coming in force of The Law of Transformation of Areas at Disaster Risks numbered 16.5.2012/6306 by Ministry of Environment and Urbanization,the concept of urban transformation has entered to our life in Turkey.Gentrification as one of the forms of urban transformation brought the existence of liberated zones produced by neo-liberal mentality.Sulukule area(Neslisah Sultan settlement)which is subject to research is counted among“the areas to be renewed and to be put under preservation”by numbered 2006/10299 decision of Council of Ministers.Due to the shortage of lands in the city,it is observed especially in 1980s that the families in high-income group have preferred to live in horizontally expending villa towns far from the center.While these residential areas are deepening the distance from the center in time,the pressure of housing demand of middle-income people and rent circles who are not planning to leave the city center caused to have an eye on these areas which are residential areas of mostly low-income people and appeared in certain regions as they are established without infrastructure and healthy conditions.With this law,the transformation has started in the areas such as Fikirtepe,Dolapdere,Esenler,and Banks of Halic(Golden Horn)where structural life is completed,and floor area ratio has been raised to 4.0 from 2.07.Vertical housing is stimulated by adding the street between the parcels to the blocks,it has been tried to prevent the victimization of local people to unearned income.There are some quarters that,under the name of gentrification,Romany citizens who passed to permanent settlement from nomadic culture at the Ottoman era,and who are engaged in activities such as handicraft,adornments,shoe making,weaving beside the show business at Fatih Sulukule district are convicted to lodge in the houses built in suburban if they have title deed,and in jerry-built tents if they don’t have deed.Chamber of Architects,Chamber of City Planners Istanbul Branch and Roma Culture Development and Solidarity Association filed“nullity suit”and“stay of execution”.Despite the continuing judicial process,the demolition started in 2009,and starting the constructing the villas in 2010 breaking the resistance of Romany citizens,the area was victimized to rent.
基金The study protocol was approved by the Marmara University School of Medicine Clinical Research Ethics Committee(Protocol No:09.2019.360,date:April 5,2019).
文摘BACKGROUND Obsessive-compulsive disorder(OCD)is a heterogeneous disease in many respects and exhibits this diversity in terms of phenomenology.It also displays several different characteristics in children compared to adults.AIM To describe the socio-demographic and phenomenological features of children with OCD and to investigate the impact of these features on response to pharmacotherapy.METHODS This retrospective study was carried out with 150 children and adolescents who had been diagnosed with OCD between 2014 and 2018.Data was collected by examining the files of the patients with diagnosis of OCD and similar disorders from the hospital database.Yale-Brown Obsessive-Compulsive Scale for Children was used for the assessment of obsession-compulsion subtypes.The Clinical Global Impression(CGI)scale was used to evaluate the severity of the disease(CGI-S)and global improvement(CGI-I).The predictors of treatment response were evaluated using linear regression analysis.The level of significance for all statistic tests was set as P<0.05.RESULTS The sample was divided into prepubertal(44%)and adolescent(56%)age groups.The most prevalent obsessions were contamination and aggression obsessions,and the most frequent compulsions were washing and checking.While contamination was observed more commonly in the prepubertal age group,the religious obsession was seen more frequently in adolescents.Patients with aggression obsession presented a higher frequency of comorbid anxiety(P=0.022)and mood subgroups(P>0.05).A lower CGI-I score was linked to a lower CGI-S score(95%confidence interval 0.21-0.39,P<0.001)and the prepubertal age of admission(95%confidence interval 0.03-0.87,P=0.020).CONCLUSION The phenomenology of OCD shows differences depending on the age group and the comorbid psychiatric disorders.Earlier identification and treatment of OCD may help to prevent the impairment of the mental health of children and adolescents.
文摘Restoration of historical buildings is important because they maintain cultural and historical continuity and transmit the cultural and social values from our precedents to future generations.Historical buildings need to adapt themselves to a changing cultural,social,economic,and political context.In this paper refunctioning project of a historic Ottoman,warehouse is presented.The aim of the project is to re-gain this historical structure for public use by re-newing it to the modern comfort level and making the required functional changes.The main structural system of the warehouse consists of thick masonry stone walls.The idea in the proposed restoration project is to build a two-story steel structure inside the available volume of the warehouse.The columns of the new steel construction run parallel to the existing structural system of the historic building and are fixed at their base to the existing building foundation.Hence,there is no connection between the proposed steel structure walls and the existing masonry walls,and this will save the historic fabric of the warehouse.The project proposal shows the details of planned restoration stages,the process of programming the new interior space,construction materials,and lighting and ventilation solutions.Furthermore,in this project,two-and threedimensional computer drawings were used.Finally,the proposed parallel steel structure is able to regain the warehouse and renew it to be used as a modern housing and workshop.
文摘Emerging evidence underscores the critical role of intestinal microbiota in postoperative recovery and long-term outcomes of gastrointestinal procedures.In this editorial,we comment on the retrospective study by Niu et al,which highlights the beneficial impact of dietary fiber supplementation on gut microbiota restoration following endoscopic mucosa resection.The findings highlight the potential of fiber supplementation to modulate gut microbiota and support recovery following endoscopic mucosa resection.Nonetheless,we also emphasize the need for prospective,randomized studies to delineate the optimal type,dose,and duration of fiber supplementation.This research represents a significant step toward evidence-based nutritional interventions in minimally invasive gastrointestinal surgery and underscores the importance of microbiota-targeted therapies in personalized postoperative care.
文摘Detection of Autism Spectrum Disorder(ASD)is a crucial area of research,representing a foundational aspect of psychological studies.The advancement of technology and the widespread adoption of machine learning methodologies have brought significant attention to this field in recent years.Interdisciplinary efforts have further propelled research into detection methods.Consequently,this study aims to contribute to both the fields of psychology and computer science.Specifically,the goal is to apply machine learning techniques to limited data for the detection of Autism Spectrum Disorder.This study is structured into two distinct phases:data preprocessing and classification.In the data preprocessing phase,four datasets—Toddler,Children,Adolescent,and Adult—were converted into numerical form,adjusted as necessary,and subsequently clustered.Clustering was performed using six different methods:Kmeans,agglomerative,DBSCAN(Density-Based Spatial Clustering of Applications with Noise),mean shift,spectral,and Birch.In the second phase,the clustered ASD data were classified.The model’s accuracy was assessed using 5-fold cross-validation to ensure robust evaluation.In total,ten distinct machine learning algorithms were employed.The findings indicate that all clustering methods demonstrated success with various classifiers.Notably,the K-means algorithm emerged as particularly effective,achieving consistent and significant results across all datasets.This study is expected to serve as a guide for improving ASD detection performance,even with minimal data availability.
文摘Even if dissociation has various facets,it is clear that knowledge of dissociative psychosis and a dissociative schizophrenia-based viewpoint may provide new perspectives on mental disorders.Many researchers screening for comorbid symptoms of“childhood traumatic experiences”and“dissociation”,where specific characteristics are significant to the presence of psychosis and schizophrenia,may lead to an acceptable definition.In recent years,researchers have also reported crucial advances in the understanding of dissociative psychosis and dissociative schizophrenia.Although clinical studies in this area have been ongoing for a long time,research has not demonstrated that a clear and valid relationship exists between dissociation,childhood traumatic experiences,and schizophrenia or psychotic spectrum disorders.However,some results of statistical comparisons have supported the existence of the clinical manifestation known as dissociative psychosis and dissociative schizophrenia.Dissociation,childhood traumatic experiences,and positive psychotic symptoms may be a prominent part of dissociative psychosis and schizophrenia.The intense presence of negative symptoms may indicate classical schizophrenia.In research and clinical practice,researchers and clinicians may use psychometric tests to detect symptoms of dissociative psychosis.Psychotic persons with traumatic experiences likely benefit from treatment focused on trauma symptomatolgy.
文摘Application of variable speed limits(VSL)is gradually increasingly implemented especially on highways.As a result of conducted studies and implementations,it is observed that the variable speed limits have reduced the number of car accidents as well as proved positive results in terms of delays and environmental factors.Purpose of this study is to develop an algorithm for VSL application that is considered to be applied on Istanbul D100 highway and to assess the effects of application.Algorithm that is developed for VSL is a different VSL algorithm and compared with the constant speed system.According to obtained results,when the proposed system is compared to current system,it is observed that the number of delays and average stops are reduced%30 and%40 respectively and also emissions reduced at the rate of%12.
文摘BACKGROUND Organ donation and transplantation are vital for saving lives,yet awareness remains limited.Health literacy,the ability to understand and use health information,and self-control,which influences decision-making,are crucial factors in promoting awareness.Understanding their relationship can guide efforts to increase participation in organ donation.AIM To investigate the effect of health literacy on organ donation and transplantation awareness,with self-control acting as a mediator,and to emphasize its importance.METHODS The study comprised 345 adults recruited from five different cities in Türkiye.The sample included 208 women(60.29%)and 137 men(39.71%).The age range of the sample group varies between 18 and 49(median age=24.13;SD=8.81).Selfreport data were collected including psychometric measures assessing organ donation and transplantation awareness,health literacy,and self-control.Reliability analysis,descriptive statistics,correlational analysis,and mediational analysis of the data were carried.RESULTS The analysis showed that health literacy was positively correlated with organ donation and transplantation awareness(r=0.340)and self-control(r=0.376).Self-control was positively related to organ donation and transplantation awareness(r=0.531).Mediating analysis supported a mediation model where health literacy was found to influence organ donation and transplantation awareness via self-control(bootstrap=0.158,95%confidence interval=0.105-0.215).CONCLUSION The results indicate that self-control mediates the positive relationship between health literacy and organ donation and transplantation awareness.Enhancing individuals’health literacy may therefore increase awareness of organ donation and transplantation through improvements in self-control.
基金the National Science Foundation of China (Grant No. NSFC: 92162213)the Geology Department Faculty of Science of Al-Azhar University (Assiut Branch)+2 种基金the China Scholarship CouncilChang'an UniversityIstanbul Technical University's Scientific Research Project (BAP Project ID: 45396, code: FHD-2024-45396)
文摘In the Fatira(Abu Zawal)mine area,located in the northern Eastern Desert of Egypt,fieldwork and mineralogical analysis,integrated with machine learning techniques applied to Landsat-8 OLI,ASTER,and Sentinel-2 multi-spectral imagery(MSI)data delineate gold-sulfide mineralization in altered rocks.Gold(Au)anomalies in hydrothermal breccias and quartz veins are associated with NE-oriented felsite dykes and silicified granitic rocks.Two main alteration types are identified:a pyrite-sericite-quartz and a sulfide-chlorite-carbonate assemblage,locally with dispersed free-milling Au specks.Dimensionality reduction techniques,including principal component analysis(PCA)and independent component analysis(ICA),enabled mapping of alteration types.Sentinel-2 PC125 composite images offered efficient lithological differentiation,while supervised classifications,i.e.,the support vector machine(SVM)of Landsat-8 yielded an accuracy of 88.55%and a Kappa value of 0.86.ASTER mineral indices contributed to map hydrothermal alteration mineral phases,including sericite,muscovite,kaolinite,and iron oxides.Results indicate that post-magmatic epigenetic hydrothermal activity significantly contributed to the Au-sulfide mineralization in the Fatira area,distinguishing it from the more prevalent orogenic gold deposits in the region.
文摘This study investigates laminar convection in three regimes(forced convection,mixed convection,and natural convection)of a bi-nanofluid(Cu-Al_(2)O_(3)-water)/mono-nanofluid(Al_(2)O_(3)-water)inside a square enclosure of sliding vertical walls which are kept at cold temperature and moving up,down,or in opposite directions.The enclosure bottom is heated partially by a central heat source of various sizes while the horizontal walls are considered adiabatic.The thermal conductivity and dynamic viscosity are dependent on temperature and nanoparticle size.The conservation equations are implemented in the solver ANSYS R2(2020).The numerical predictions are successfully validated by comparison with data from the literature.Numerical simulations are carried out for various volume fractions of solid mono/hybrid-nanoparticles(0≤ϕ≤5%),Richardson numbers(0.001≤Ri≤10),and hot source lengths((1/5)H≤ε≤(4/5)H).Isothermal lines,streamlines,and average Nusselt numbers are analyzed.The thermal performance of nanofluids is compared to that of the base heat transfer fluid(water).Outcomes illustrate the flow characteristics significantly affected by the convection regime,hot source size,sidewall motion,and concentration of solid nanoparticles.In the case of sidewalls moving downward,using hybrid nanofluid(Cu-Al_(2)O_(3)-water)shows the highest heat transfer rate in the enclosure at Ri=1,ε=(4/5)H and volume fraction ofφ=5%where a significant increment(25.14%)of Nusselt number is obtained.
文摘Delayed wound healing following radical gastrectomy remains an important yet underappreciated complication that prolongs hospitalization,increases costs,and undermines patient recovery.In An et al’s recent study,the authors present a machine learning-based risk prediction approach using routinely available clinical and laboratory parameters.Among the evaluated algorithms,a decision tree model demonstrated excellent discrimination,achieving an area under the curve of 0.951 in the validation set and notably identifying all true cases of delayed wound healing at the Youden index threshold.The inclusion of variables such as drainage duration,preoperative white blood cell and neutrophil counts,alongside age and sex,highlights the pragmatic appeal of the model for early postoperative monitoring.Nevertheless,several aspects warrant critical reflection,including the reliance on a postoperative variable(drainage duration),internal validation only,and certain reporting inconsistencies.This letter underscores both the promise and the limitations of adopting interpretable machine learning models in perioperative care.We advocate for transparent reporting,external validation,and careful consideration of clinically actionable timepoints before integration into practice.Ultimately,this work represents a valuable step toward precision risk stratification in gastric cancer surgery,and sets the stage for multicenter,prospective evaluations.
基金supported by Istanbul Technical University(Project No.45698)supported through the“Young Researchers’Career Development Project-training of doctoral students”of the Croatian Science Foundation.
文摘This paper investigates the reliability of internal marine combustion engines using an integrated approach that combines Fault Tree Analysis(FTA)and Bayesian Networks(BN).FTA provides a structured,top-down method for identifying critical failure modes and their root causes,while BN introduces flexibility in probabilistic reasoning,enabling dynamic updates based on new evidence.This dual methodology overcomes the limitations of static FTA models,offering a comprehensive framework for system reliability analysis.Critical failures,including External Leakage(ELU),Failure to Start(FTS),and Overheating(OHE),were identified as key risks.By incorporating redundancy into high-risk components such as pumps and batteries,the likelihood of these failures was significantly reduced.For instance,redundant pumps reduced the probability of ELU by 31.88%,while additional batteries decreased the occurrence of FTS by 36.45%.The results underscore the practical benefits of combining FTA and BN for enhancing system reliability,particularly in maritime applications where operational safety and efficiency are critical.This research provides valuable insights for maintenance planning and highlights the importance of redundancy in critical systems,especially as the industry transitions toward more autonomous vessels.
文摘Recently, important land use changes have occurred in the Black Sea coastal regions of istanbul due to urban growth and population increases. The objective of this study was to determine changes in land use in the Black Sea coastal regions of Jstanbul between 1987 and 2007. Landsat 30 m satellite images from 1987 and 2007 are used in the study. The study area is 1000 m in width from the coastline to the land and the study has been carried out using the controlled classification method to classify areas into residential, agricultural, forest, bare land, brush/grassland, and lake/pond land classes. Land use changes between 1987 and 2007 were analysed in detail. Residential areas of the Black Sea coastal regions of istanbul increased by 122% over the two decades. Also an increase of 55% in agriculture areas was observed, while there were decreases of 26% in forest areas and 15% in free land. A 21% increase in the area of brush and grassland took place. Furthermore 79% of the study area was covered by residential areas in 2007. It is probable that pressure on the Jstanbul coastal regions will continue due to migraton and rapid urbanization. Therefore, Istanbul＇s Black Sea coastal regions should be maintained using a sustainable coastal management plan.
文摘Neoplastic proliferation of plasma cells is called plasma cell dyscrasias, and these neoplasms can present as a solitary neoplasm or multiple myeloma. Extramedullary plasmacytoma, in particular pancreatic plasmacytoma, is a rare manifestation of multiple myeloma. Although computerized tomography is useful for the diagnosis of extramedullary plasmacytoma, there are no specific radiologic markers that distinguish it from adenocarcinoma. Histological confirmation by biopsy is necessary for accurate diagnosis and management of the tumor. Endosonography is the most sensitive method for the diagnosis of pancreatic tumors, and the use of fine needle aspiration by endosonography is associated with a lower risk for malignant seeding and complications. Here, we report a case of pancreatic plasmacytoma in newly identified multiple myeloma as diagnosed by endosonography. Endosonography is a reliable and rapid method for the diagnosis of extramedullary plasmacytoma. Therefore, endosonographic fine needle aspiration should be the first choice for histological evaluation when pancreatic plasmacytoma is suspected. Ideally, the pathology would be performed at the same site as endosonographic biopsy.
文摘AIM: To assess lung parenchymal changes in ankylosing spondylitis (AS) using high resolution computed tomography (HRCT). METHODS: We included 78 AS patients whose average age was 33.87 (18-56) years with a ratio of 53 males to 25 females who were followed up for 3.88 (1-22) years on average. neumonia and tuberculosis were excluded. In a detailed examination of lung HRCT findings, we investigated the presence of parenchymal micronodules,parenchymal bands, subpleural bands, interlobular and intralobular septal thickening, irregularity of interfaces,ground glass opacity, consolidation, mosaic pattern,bronchial wall thickening, bronchial dilatation, tracheal dilatation, pleural thickening, emphysema, thoracic cage asymmetry, honeycomb appearance, structural distortion, apical fibrosis and other additional findings.RESULTS: In detailed HRCT evaluations, lung parenchymal changes were found in 46 (59%) of all patients. We found parenchymal bands in 21 (27%) cases, interlobular septal thickening in 9 (12%), emphysema in 9 (12%), apical fibrosis in 8 (10%), ground-glass opacities in 7 (9%), parenchymal micronodules in 5 (6%), irregularity in interfaces in 3 (4%), bronchial dilatation in 3 (4%), mosaic pattern in 2 (3%), pleural thickening in 2 (3%), consolidation in 1 (1%), bronchial wall thick ening in 1 (1%) and a subpleural band in 1 (1%) case. Furthermore, we detected subsegmental atelectasis in 2 patients and a cavitary lesion in 1 patient. CONCLUSION: Our study had the highest number of AS cases of all previous studies in evaluating lung paren chymal changes. The rate of lung parenchymal changes was slightly lower than that reported in recent literature.
文摘BACKGROUND Children diagnosed with autism spectrum disorder(ASD)may have great difficulties when their routines change,and this may affect the psychological wellbeing of their parents.For this reason,it is important to examine studies that address the mental health of parents in order to adapt to the coronavirus disease 2019(COVID-19)pandemic.AIM To determine the mental health status of parents with children diagnosed with ASD in the COVID-19 pandemic.METHODS The study,which is a systematic review,was conducted between December 15,2020 and December 30,2020 by scanning articles in English.The Scopus,Science Direct,PubMed,Cochrane,Web of Science,and Google Scholar databases were used for scanning.The keywords COVID-19 AND(“autism”OR“autistic”OR“autism spectrum disorder”)AND parent AND(“mental health”OR“anxiety”OR“stress”)were used in the search process.The inclusion criteria in the study were findings regarding the mental health of parents with children diagnosed with ASD in the COVID-19 pandemic,addressing their anxiety and stress situations,being a research article,and accessing the full text of the article.RESULTS In the study,a total of 6389 articles were reached,and the full texts of 173 articles were evaluated for eligibility.After the articles excluded by the full-text search were eliminated,12 studies involving 7105 parents were included in the analysis.The findings obtained from the articles containing data on mental health in the COVID-19 pandemic of parents with children with autism spectrum disorder were discussed in three groups.These were findings on the experiences of parents with children with ASD in the COVID-19 pandemic regarding the areas where parents with children with ASD need support in the COVID-19 pandemic and methods of coping with the COVID-19 pandemic for parents with children with ASD.In the systematic review,it was determined that the anxiety and stress of the parents increased,they needed more support compared to the pre-pandemic period,and they had difficulty coping.CONCLUSION In this systematic review,it was concluded that the COVID-19 pandemic negatively affected the mental health of the parents of children with ASD.
基金This work was supported by Scientific Research Projects Coordination Unit of Istanbul University-Cerrahpasa(Project No.FYD-2016-20102).
文摘Background:Thinning is a commonly used treatment in forest management which affects the tree root systems.The effects of thinning on element concentrations and seasonal change of roots were evaluated in adjacent oak(Quercus frainetto Ten.)and hornbeam(Carpinus betulus L.)stands according to the different root diameter classes.Method:Two replicated control and thinning plots(50m×50 m)were set for each species(hornbeam and oak).Thinning treatments(November 2010)reduced 50%of the basal area in both oak and hornbeam stands.Roots were assessed by seasonal collection over 2 years(from October 2010 to October 2012).The roots were then sorted into diameter classes of 0–2mm(fine roots),2–5mm(small roots)and>5mm(coarse roots).C,N,P,K,Ca,Na,Mg,S,Mn,Fe,Al,Zn,Pb,Ni,Cu and Cd were analyzed.Results:Except coarse roots,the highest root biomasses were determined in April-2011 in all plots.Fine-root biomass in oak was found significantly higher in control plots.In contrast to the oak,the fine-root biomass in the thinned hornbeam plots was higher than in the controls.The small-root biomass did not significantly differ between the thinned and the control plots in both oak and hornbeam stands.However,the coarse-root biomass showed significant differences between the control(1989 g∙m^(−2))and thinned plots(1060 g∙m^(−2))in oak,while no difference was detected in hornbeam.The concentrations of C,Al,Pb,Cd,Ni,Zn,Mn,Na,K,Mg and P in the fine roots of oak were significantly higher in the thinned plots.However,the concentration of Pb,Cd and Fe in the fine roots was significantly higher in the thinned plots of hornbeam.Significant differences were observed between the species for all elements in the fine roots except for C,N and P.In particular,elements in the fine roots tended to increase in July in the oak.In the hornbeam,all element concentrations in the fine roots(except C,N,and S)in the thinned plots showed a tendency to increase in April.The concentrations of Pb,Ni,Al,Fe,Cu,Ca,Na,K,Mg and P in the hornbeam control plots increased during the April 2011 period.Conclusion:The results indicated that thinning effects on temporal changes and concentrations of elements in the roots could be attributed to species-specific characteristics.
