Type 2 diabetes(T2D)is a chronic metabolic disorder marked by insulin resistance and impaired glucose metabolism,often diagnosed at advanced stages[1].Metabolomics offers a promising approach for identifying biomarker...Type 2 diabetes(T2D)is a chronic metabolic disorder marked by insulin resistance and impaired glucose metabolism,often diagnosed at advanced stages[1].Metabolomics offers a promising approach for identifying biomarkers to detect T2D early[2].This longitudinal study uses Korean Genome and Epidemiology Study(KoGES)data,a cohort of 10,300 individuals aged 40-69 years recruited in 2001-2002,with biennial follow-ups.The study included 664 participants from phases 6-8(2012-2016)with complete metabolomic data[3].The aim was to find novel metabolite biomarkers associated with T2D risk.展开更多
基金supported by the National Research Foundation of Korea(NRF),funded by the Ministry of Education(NRF-2022R1A2C1092497)。
文摘Type 2 diabetes(T2D)is a chronic metabolic disorder marked by insulin resistance and impaired glucose metabolism,often diagnosed at advanced stages[1].Metabolomics offers a promising approach for identifying biomarkers to detect T2D early[2].This longitudinal study uses Korean Genome and Epidemiology Study(KoGES)data,a cohort of 10,300 individuals aged 40-69 years recruited in 2001-2002,with biennial follow-ups.The study included 664 participants from phases 6-8(2012-2016)with complete metabolomic data[3].The aim was to find novel metabolite biomarkers associated with T2D risk.
