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Accurate laser skin perforation technique aimed at promoting bleeding and reducing pain
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作者 Han-Chao Chang Yu-Hsuan Lin Kuo-Cheng Huang 《Journal of Innovative Optical Health Sciences》 SCIE EI CAS 2015年第6期9-16,共8页
Laser skin perforation is an effective and promising technique for use in blood collection.In this study,the relation between the perforation profile of skin and laser irradiation at various energies is discussed.Incr... Laser skin perforation is an effective and promising technique for use in blood collection.In this study,the relation between the perforation profile of skin and laser irradiation at various energies is discussed.Increasing laser energy does not uniformly expand the size and depth of a hole because the shallow depth of field(DOF)of the focused light primarily concentrates energy on the skin surface.In practice,the hole gradually transforms from a semielliptical shape to an upsidedown avocado shape as the laser energy increases.This phenomenon can increase the amount of bleeding and reduce pain.The findings support the feasibility of developing an accurate laser skin perforation method. 展开更多
关键词 Laser skin perforation blood collection Er YAG laser DIABETIC
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Pixel Discontinuity Repairing for Push-Broom Orthorectified Images
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作者 Jyun-Yi Lai Ming-Fu Chen Han-Chao Chang 《Journal of Software Engineering and Applications》 2013年第4期24-29,共6页
Pixel discontinuity in orthoimages occurs frequently due to altitude variations in the pitch and heading of an airplane, and low performance of real-time analyzing software. This study proposes a scheme to resolve pix... Pixel discontinuity in orthoimages occurs frequently due to altitude variations in the pitch and heading of an airplane, and low performance of real-time analyzing software. This study proposes a scheme to resolve pixel discontinuity. The proposed scheme includes the following steps: 1) capture images by a self-made hyperspectral imager;2) determine the pixel locations of orthoimages using a top-down approach;3) repair discontinuities by the Nearest Neighbor (NN) or Bilinear Interpolation (BL) approaches;and, 4) perform a dynamic range adjustment on the orthoimages, according to the maximum pixel value of the raw images and orthoimages. After applying the proposed scheme, this study found that pixel discontinuity was eliminated by both approaches, and that the software dependability and image quality were improved substantially. In addition, the computational efficiency of the NN approach was roughly two minutes faster than that of the BL due to its simpler computation. However, BL produces smoother image edges for landscapes. 展开更多
关键词 PIXEL DISCONTINUITY REAL-TIME ANALYZING SOFTWARE TOP-DOWN Approach Orthorectification
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Microfluidic Electrochemical Detection Techniques of Cancer Biomarkers 被引量:1
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作者 Yao Xie Di Chen Shujing Lin 《Nano Biomedicine & Engineering》 2017年第1期57-71,共15页
Microfluidic electrochemical sensors are based on the immune response.Immune charge density or electrode potential and other parameters sensitive interface causes a change or cause a power solution of the active ingre... Microfluidic electrochemical sensors are based on the immune response.Immune charge density or electrode potential and other parameters sensitive interface causes a change or cause a power solution of the active ingredient(or their related components)to generate or consume,causing the detected current or potential.The electrochemical parameters of the law of changing enable the immune proteins quantitative or qualitative detection.Since the immune protein molecules themselves are typically non-electrochemical activity,and therefore immune electrochemical sensor usually mark the electrically active substance or enzyme in the antigen or antibody molecules in solution antigen(antibody)immune response and by the immobilized antigen(antibody)the concentration of the sample antigen(antibody)after the change of the current signal,causing the electro-active substance or enzyme-catalyzed reaction of substrate reaction can be determined indirectly. 展开更多
关键词 Microfluidic Cancer biomarkers Elelctrochemical detection
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