Brain-computer interfaces(BCIs)represent an emerging technology that facilitates direct communication between the brain and external devices.In recent years,numerous review articles have explored various aspects of BC...Brain-computer interfaces(BCIs)represent an emerging technology that facilitates direct communication between the brain and external devices.In recent years,numerous review articles have explored various aspects of BCIs,including their fundamental principles,technical advancements,and applications in specific domains.However,these reviews often focus on signal processing,hardware development,or limited applications such as motor rehabilitation or communication.This paper aims to offer a comprehensive review of recent electroencephalogram(EEG)-based BCI applications in the medical field across 8 critical areas,encompassing rehabilitation,daily communication,epilepsy,cerebral resuscitation,sleep,neurodegenerative diseases,anesthesiology,and emotion recognition.Moreover,the current challenges and future trends of BCIs were also discussed,including personal privacy and ethical concerns,network security vulnerabilities,safety issues,and biocompatibility.展开更多
BACKGROUND Antimicrobial resistance(AMR)is an escalating global health threat,disproportionately impacting low-income and middle-income countries like India.The rise of multidrug-resistant organisms(MDROs)complicates ...BACKGROUND Antimicrobial resistance(AMR)is an escalating global health threat,disproportionately impacting low-income and middle-income countries like India.The rise of multidrug-resistant organisms(MDROs)complicates treatment,increases healthcare costs,and contributes to higher morbidity and mortality.In India,factors such as antibiotic misuse,over-the-counter availability,and self-medication have exacerbated this crisis.Despite the urgency,regional data on MDRO prevalence remains limited.AIM To assess the burden and distribution of MDRO infections identified at a tertiary healthcare institute in North India.METHODS This cross-sectional study analyzed inpatient data from All India Institute of Medical Sciences(AIIMS)Rishikesh using the E-hospital database from May 2021 to February 2024,except 2022.All inpatients with culture-confirmed MDRO infections were included.Patient charts and discharge summaries were reviewed.Data analysis was performed using Jamovi software,with descriptive statistics summarizing demographics.Theχ²test was used to assess associations between MDROs and various factors.Ethical approval was obtained,and patient confidentiality was maintained.RESULTS This study included 820 participants having 1106 MDROs.The majority of patients were aged 35-64 years,with a male predominance(57.6%).Most cases were from Uttar Pradesh(49.1%)and Uttarakhand(47.6%),with Bijnor and Haridwar districts reporting the highest burden from their respective states.Klebsiella pneumoniae(K.pneumoniae)(30.6%),Acinetobacter baumannii(16.7%),and Escherichia coli(E.coli)(16.7%)were the most common MDROs.Urine was the most frequent sample type(51.0%),with K.pneumoniae as the leading pathogen.Infections varied significantly across departments(P<0.001),with General Medicine and Surgery reporting the highest burden.E.coli and Klebsiella spp.were most prevalent in these departments respectively.MDRO prevalence fluctuated over time,with significant variations by quarter(P<0.001).Following the second coronavirus disease 2019 wave,there was a rapid surge in MDROs,which stabilized after approximately three months.The overall mortality among patients harboring MDROs was 25.9%.CONCLUSION This study highlights the burden of MDROs among patients at AIIMS Rishikesh,with K.pneumoniae as the predominant pathogen.Strengthening antimicrobial stewardship and infection control measures is essential to combat rising AMR,with department-specific,and pathogen-specific stewardships.展开更多
Since the reform and opening up,the development approach targeting urban economic growth has led to a sharp increase in the proportion of impervious hardened surfaces in cities and significant waste of natural resourc...Since the reform and opening up,the development approach targeting urban economic growth has led to a sharp increase in the proportion of impervious hardened surfaces in cities and significant waste of natural resources.The urgent need for water ecological civilization construction is of great significance to the continuation of human civilization in the long run.This paper focuses on the urban waterfront landscape design of the Chongqing Institute of Engineering section of the Huaxi River in Banan District,emphasizing the concept of“symbiosis”.Using site cultural symbols as a medium to connect the campus and the city on both sides of the river,returning the riverbank to the people,restoring the ecological space of the riverfront,enriching the landscape belt,promoting the protection of bird and fish habitats,and stimulating the vitality of the riverbank space;it aims to pave the way for ecological restoration,functional expansion,landscape renewal,and riverfront space activation at the study site.展开更多
The software technology field is facing new talent demands brought by the Information Technology Application Innovation(ITAI)industry.This paper takes Shanwei Institute of Technology as an example to deeply explore th...The software technology field is facing new talent demands brought by the Information Technology Application Innovation(ITAI)industry.This paper takes Shanwei Institute of Technology as an example to deeply explore the construction of a school-enterprise community education model driven by the ITAI industry.It establishes the Kirin Workshop training base to facilitate talent cultivation,integrates the ITAI Application Adaptation Center to enhance technical capabilities,cooperates with Liqi Technology to establish an industrial college for government talent training,adjusts the professional curriculum system,and arranges for students to participate in ITAI vocational skills competitions.The school-enterprise collaborative cultivation mechanism meets the talent needs of the ITAI field,with effective practical results.This paper also points out the shortcomings of the school-enterprise collaborative education model in the ITAI industry and provides optimization methods to explore new paths for industry-education integration and serve the development of regional and national ITAI industries^([1]).展开更多
Introduction: Malignant sylvian infarction (MSI) is a type of ischemic stroke (ICS) usually affecting the entire territory of the middle cerebral artery (MCA) associated with significant cerebral edema and a mass. It ...Introduction: Malignant sylvian infarction (MSI) is a type of ischemic stroke (ICS) usually affecting the entire territory of the middle cerebral artery (MCA) associated with significant cerebral edema and a mass. It represents about 10% of all AICs, with a mortality of up to 80%. The objectives of our study were to describe the sociodemographic profile and the main clinical manifestations and identify the prognostic factors of ISM. Material and Methods: We conducted a retrospective descriptive study over a 2-year period. It included patients hospitalized for cerebral infarction involving 2/3 of the ACM territory with a NIHSS score ≥ 17 and/or a Glasgow score Results: We collected 223 patients hospitalized for ischemic stroke, of whom 21 patients (9.4%) presented with ISM. The mean age was 57.43 ± 24.24 years with a male predominance (52.4%). The mean admission time was 47 ± 0.87 hours, and hemiplegia was the frequent neurological sign (85.7%). HBP was the common cardiovascular risk factor (76.2%). The mean NIHSS at admission was 18.38 ± 12.29. Respiratory distress (p-value = 0.00015), aspiration pneumonia (p-value = 0.015) and brain herniation (p-value = 0.014) were the main complications associated with mortality. Conclusion: ISM is associated with poor prognosis in the absence of surgical treatment. Respiratory distress, aspiration pneumonia and brain herniation are associated with high mortality.展开更多
The prompt fission neutron spectrum(PFNS)is a key nuclear data quantity that is of particular interest and plays a crucial role in understanding and modeling fission processes.An array comprising 48 liquid scintillati...The prompt fission neutron spectrum(PFNS)is a key nuclear data quantity that is of particular interest and plays a crucial role in understanding and modeling fission processes.An array comprising 48 liquid scintillation detectors and a parallelplate avalanche counter(PPAC)was developed at the China Institute of Atomic Energy(CIAE)to measure the PFNS of actinide nuclei.Efficiency and energy calibrations were performed for all the liquid scintillators,and their efficiencies were consistently found to be better than 5%.The time resolutions of the PPAC and liquid scintillators were measured to be 1.08 ns and 1.16 ns using~(252)Cf and~(207)Bi sources,respectively.The pulse shape discrimination of the liquid scintillator was utilized to identify neutron andγsignals on an event-by-event basis,and the figure of merit was deduced as 1.12 at a 200 ke Vee threshold.The contribution to the PFNS from multiple scattered neutrons was evaluated via Geant4 simulations,and those originating from the environment were found to be comparable to the crosstalk between the detectors.The neutron efficiency of the entire detection array was calibrated using a~(252)Cf spontaneous fission source and was demonstrated to be consistent with the Geant4 simulation results,which verified the reliability of the detection array.展开更多
Addressing the core weaknesses in the innovation and entrepreneurship capabilities of vocational college graduates,such as market insight and risk tolerance,as well as issues with the existing training model,including...Addressing the core weaknesses in the innovation and entrepreneurship capabilities of vocational college graduates,such as market insight and risk tolerance,as well as issues with the existing training model,including courses that are disconnected from industry,a lack of systematic practical training,and superficial school-enterprise cooperation,this paper constructs a“three-dimensional,four-dimensional”training system.The“three-dimensional”foundational framework encompasses three pillars:curriculum,general education layer,professional integration layer,practical application layer,practice as in three stages:introductory,simulated,and practical,and support including dual mentors,policies,and platforms.The“four-dimensional”differentiated strategies include four implementation pathways:professional differentiation,stage differentiation,addressing capability shortcomings,and school-government-industry collaboration.This system is grounded in theories such as multiple intelligences theory and systems theory,forming a closed-loop process of“theoretical input—practical application—support mechanisms”.Based on the practices of Guangdong Vocational Institute of Public Administration,the paper proposes a competency development pathway tailored by major and stage,which can effectively enhance the innovative and entrepreneurial core competencies of vocational college graduates.This provides a replicable systematic solution for vocational college innovative and entrepreneurial education,supporting vocational education reform and regional economic development.展开更多
In response to the current issues in the construction of software engineering(SE)degree granting program,such as insufficient resource integration,low level of internationalization,and inadequate quality control,we pr...In response to the current issues in the construction of software engineering(SE)degree granting program,such as insufficient resource integration,low level of internationalization,and inadequate quality control,we propose the Software Engineering Degree Granting Program Construction Practice Project at Harbin Institute of Technology(HIT).This project aims to explore new models for software talent cultivation,establish a superior SE degree granting program,and ultimately cultivate outstanding internationalized composite SE professionals to support the high-quality development of the national software industry.To this end,we design a distinctive overall construction idea and plan for the SE degree granting program,which are characterized by“3I3S:three highlights for specialized cultivation and strictness in three aspects to ensure quality control”.After years of practice and validation of the project at the School of Software at HIT,this project has proven effective in optimizing talent cultivation models,enhancing students’practical abilities,promoting international exchange and cooperation,advancing industry-education integration,and meeting industrial needs.展开更多
Irrigation service defines the responsibilities and rights of irrigation system management agencies,water users,and other parties involved in the irrigation service contract.As a result,the irrigation service must be ...Irrigation service defines the responsibilities and rights of irrigation system management agencies,water users,and other parties involved in the irrigation service contract.As a result,the irrigation service must be clearly specified and updated by crop seasons and by all partners.Given the inherent complexity of the service,this article presents and discusses the development and application of a computer model designed to support the specification of public service levels in rice-based irrigation systems.Applied to the Tu Mai irrigation system,the model has enabled all involved parties to define irrigation service levels through systematic analysis and a thorough consideration of constraints such as water resource characteristics,hydraulic structures,and the operational plans of the irrigation system.The research findings have also helped relevant agencies reach agreements on irrigation service levels for the particular irrigation season of spring 2023,which included one irrigation period for land preparation and five subsequent irrigation periods for rice crops corresponding with a specific schedule for operating the system(discharges and duration)that met the farmers’requests for their farming practices and reduced the loss due to rice crop yield decline at the irrigation system as a whole.Additionally,recommendations for improving irrigation services in the Tu Mai system have been made,including upgrading the head pumping station to accommodate lower water levels in the Cau River,aligning the irrigation schedules of the Water User Associations(WUAs)more flexibly,and strictly supervising water deliveries to ensure safety and fairness.展开更多
Traditional psychological treatment methods often require a long time and have limited effects.Researchers have begun to explore the combination of brain-computer interface(BCI)technology and mental health,providing n...Traditional psychological treatment methods often require a long time and have limited effects.Researchers have begun to explore the combination of brain-computer interface(BCI)technology and mental health,providing new possibilities for the treatment and rehabilitation of mental illnesses.This paper reviews the advantages,existing risks,and challenges of BCI technology in mental health treatment,and prospects the future development of research on BCI and mental health.展开更多
Introduction: Pain has been defined for more than 20 years by the International Association for the Study of Pain (IASP) as an unpleasant sensory and emotional experience associated with actual or potential tissue dam...Introduction: Pain has been defined for more than 20 years by the International Association for the Study of Pain (IASP) as an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage. It has been recognized as a feature of Parkinson’s disease (PD) since the first descriptions of the disease. Material and Methods: This was a prospective descriptive study lasting six (06) months from November 1, 2023 to April 30, 2024. We included all patients diagnosed with PD and who had pain. Sociodemographic, clinical, paraclinical and therapeutic data were evaluated for each patient. Results: We identified a sample of 62 Parkinson’s patients, of whom 52 patients or 85.2% had associated pain. We noted a male predominance (38M/14F) and a sex ratio of 2.71. Musculoskeletal pain was common in 80% of our respondents. WHO level I, antidepressants and background treatment for KD were the most prescribed molecules. Conclusion: Our study shows a frequency of pain in PD. However, musculoskeletal pain is the most frequently encountered type of pain in PD patients. WHO step I analgesics, antidepressants and background treatment of KD were the main prescriptions in our study.展开更多
The advancement of fibre electronics is crucial for developing wearable smart textiles.However,traditional single-function fibres are typically limited to basic sensing and data collection capabilities,lacking effecti...The advancement of fibre electronics is crucial for developing wearable smart textiles.However,traditional single-function fibres are typically limited to basic sensing and data collection capabilities,lacking effective computational and multimodal signal processing abilities,thus significantly restricting their potential in human activity recognition.Recently,Gupta et al.introduced an innovative single-fibre computer embedding eight microelectronic devices,integrating sensing,communication,and computation into a single fibre.Establishing a distributed cooperative fibre network substantially enhanced human activity recognition accuracy from 67%(single-fibre scenario)to 95%.This novel approach effectively addresses the limitations of conventional smart fibres,paving the way for multi-point sensing,edge-based inference,and realtime human-computer interactions in future intelligent textiles.展开更多
Purpose:Interdisciplinary research has become a critical approach to addressing complex societal,economic,technological,and environmental challenges,driving innovation and integrating scientific knowledge.While interd...Purpose:Interdisciplinary research has become a critical approach to addressing complex societal,economic,technological,and environmental challenges,driving innovation and integrating scientific knowledge.While interdisciplinarity indicators are widely used to evaluate research performance,the impact of classification granularity on these assessments remains underexplored.Design/methodology/approach:This study investigates how different levels of classification granularity-macro,meso,and micro-affect the evaluation of interdisciplinarity in research institutes.Using a dataset of 262 institutes from four major German non-university organizations(FHG,HGF,MPG,WGL)from 2018 to 2022,we examine inconsistencies in interdisciplinarity across levels,analyze ranking changes,and explore the influence of institutional fields and research focus(applied vs.basic).Findings:Our findings reveal significant inconsistencies in interdisciplinarity across classification levels,with rankings varying substantially.Notably,the Fraunhofer Society(FHG),which performs well at the macro level,experiences significant ranking declines at meso and micro levels.Normalizing interdisciplinarity by research field confirmed that these declines persist.The research focus of institutes,whether applied,basic,or mixed,does not significantly explain the observed ranking dynamics.Research limitations:This study has only considered the publication-based dimension of institutional interdisciplinarity and has not explored other aspects.Practical implications:The findings provide insights for policymakers,research managers,and scholars to better interpret interdisciplinarity metrics and support interdisciplinary research effectively.Originality/value:This study underscores the critical role of classification granularity in interdisciplinarity assessment and emphasizes the need for standardized approaches to ensure robust and fair evaluations.展开更多
Background Clinical brain-computer interface(BCI)for mental disorders is an emerging interdisciplinary research field,posing new ethical concerns and challenges,yet lacking practical ethical governance guidelines for ...Background Clinical brain-computer interface(BCI)for mental disorders is an emerging interdisciplinary research field,posing new ethical concerns and challenges,yet lacking practical ethical governance guidelines for stakeholders and the entire community.Aims This study aims to establish a multidisciplinary consensus of principles for ethical governance of clinical BCI research for mental disorders and offer practical ethical guidance to stakeholders involved.Methods A systematic literature review,symposium and roundtable discussions,and a pre-Delphi(round 0)survey were conducted to form the questionnaire for the three-round modified Delphi study.Two rounds of surveys,followed by a third round of independent interviews of 25 experts from BCI-related research domains,were involved.We conducted quantitative analysis of responses and agreements among experts to reveal the consensus and differences regarding the ethical governance of mental BCI research from a multidisciplinary perspective.Results The Delphi panel emphasised important concerns of ethical review practices and ethical principles within the BCI context,identified qualified and highly influential institutions and personnel in conducting and advancing clinical BCI research,and recognised prioritised aspects in the risk-benefit evaluation.Experts expressed diverse opinions on specific ethical concerns,including concerns about invasive technology,its impact on humanity and potential social consequences.Agreement was reached that the practices of ethical governance of clinical BCI for mental disorders should focus on patient voluntariness,autonomy,long-term effects and related assessments of BCI interventions,as well as privacy protection,transparent reporting and ensuring that the research is conducted in qualified institutions with strong data security.Conclusions Ethical governance of clinical research on BCI for mental disorders should include interdisciplinary experts to balance various needs and incorporate the expertise of different stakeholders to avoid serious ethical issues.It requires scientifically grounded approaches,continuous monitoring and interdisciplinary collaboration to ensure evidence-based policies,comprehensive risk assessments and transparency,thereby promoting responsible innovations and protecting patient rights and well-being.展开更多
We selected a cell with superior electrochemical performance to characterization microstructure characterization.Here,we employed high-resolution SEM and X-ray nano-CT to investigate a porous LSCrRu-GDC composite anod...We selected a cell with superior electrochemical performance to characterization microstructure characterization.Here,we employed high-resolution SEM and X-ray nano-CT to investigate a porous LSCrRu-GDC composite anode.These experimental results are utilized for characterize and quantify the key structural parameters,such as the volume ratio of the three phases(LSCrRu,GDC,and pore),connected porosity,tortuosity,surface area of each phase,interface of LSCrRu/GDC,and three-phase boundary length(TPB where the LSCrRu,GDC and fuel gas phases come together)of the anode.展开更多
Accurate estimation on the state of health(SOH)is essential for ensuring the safe and reliable operation of batteries.Traditional assessment methods primarily focus on electrical attributes for capacity decay,often ov...Accurate estimation on the state of health(SOH)is essential for ensuring the safe and reliable operation of batteries.Traditional assessment methods primarily focus on electrical attributes for capacity decay,often overlooking the impact of thermal distribution on battery aging.However,thermal effect is a critical factor for degradation process and associated risks throughout their service life.In this paper,we introduce a novel deep learning framework specially designed to estimate the capacity and thermal risks of lithium-ion batteries(LIBs).This model consists of two main components that leverage computer vision technology.One predicts battery capacity by integrating the advantages of thermal and electrical features using a temporal pattern attention(TPA)mechanism,while the other assesses thermal risk by incorporating temperature variation to provide early warnings of potential hazards.An infrared camera is deployed to record temperature evolution of LIBs during the electrochemical process.The thermal heterogeneities are recorded by infrared camera,and the corresponding temperature evolutions are extracted as representative features for analysis.The proposed model demonstrates high accuracy and stability,with an average root mean square error(RMSE)of 0.67% for capacity estimation and accuracy exceeding 93.9% for risk prediction,underscoring the importance of integrating spatial temperature distribution into battery health assessments.This work offers valuable insights for the development of intelligent and robust battery management systems.展开更多
Introduction: Vitamin D plays a key role in phosphocalcic metabolism, in normal functioning of the immune system and in the prevention of certain forms of cancer. Systematic vitamin D supplementation has been implemen...Introduction: Vitamin D plays a key role in phosphocalcic metabolism, in normal functioning of the immune system and in the prevention of certain forms of cancer. Systematic vitamin D supplementation has been implemented in most Western countries, which has drastically reduced the prevalence of rickets. In Senegal, a country with enough sunshine, no large-scale data exists on vitamin D deficiency in children. In addition, there are no guidelines from the Ministry of Health and Social Action (MoHSA) on vitamin D supplementation. Our objective was to determine the prevalence of vitamin D deficiency in children aged 6 to 59 months and to analyze the factors associated with it at the Institute of Social Pediatrics in Pikine-Guédiawaye, a suburb of Dakar. Patients and Methods: This was a prospective, descriptive and analytical cross-sectional study over a 3-month period (from January to March 2024) at the Institute of Social Pediatric (IPS) of Pikine-Guédiawaye. The study population consisted of all children aged 6 to 59 months free from any acute or chronic pathology, whose parents had agreed to answer the questionnaires after having consented and signed the consent and children who had had a sample taken for vitamin D dosage. Results: We included 102 children, 35 of whom had vitamin D deficiency, i.e. a prevalence of 34.31% with a slight male predominance (sex ratio 1.05). Infants aged 13 - 24 months were more affected (41.67%), but the difference was not statistically significant (p-value = 0.385). Patients with acute malnutrition had a significantly higher prevalence of vitamin D deficiency (54.17% of cases versus 28.38%) in those without acute malnutrition (p = 0.02). On the other hand, chronic malnutrition, underweight and diversification foods were not significantly associated with vitamin D deficiency (p of 0.60, 0.42 and 0.09 respectively). Conclusion: Vitamin deficiency affects one-third of apparently healthy children under 5 and this deficiency has no significant relationship with diversification foods. This suggests that the observed vitamin D deficiencies are less related to diet than to lack of sun exposure.展开更多
BACKGROUND:In clinical practice,some patients might not be able or unwilling to provide a thorough history of medication and poison exposure.The aim of this study was to use toxicological analysis to examine the clini...BACKGROUND:In clinical practice,some patients might not be able or unwilling to provide a thorough history of medication and poison exposure.The aim of this study was to use toxicological analysis to examine the clinical characteristics of patients with acute poisoning whose exposure history was uncertain from a toxicological analysis perspective.METHODS:This was a retrospective and descriptive study from an institute of poisoning.Patient registration information and test reports spanning the period from April 1,2020 to March 31,2022,were obtained.Patients with uncertain exposure histories and who underwent toxicological analysis were included.Clinical manifestations and categories of toxics were analyzed.RESULTS:Among the 195 patients with positive toxicological analysis results,the main causes of uncertain exposure history was disturbance of consciousness(62.6%),unawareness(23.6%)and unwillingness or lack of cooperation(13.8%).The predominant clinical manifestations were disturbed consciousness(62.6%),followed by vomiting and nausea(14.4%)and liver function abnormalities(8.7%).A comparison of clinical manifestations between patients with positive and negative(n=99)toxicological analyses results revealed significantly different proportions of disturbances in consciousness(63%vs.21%),dizziness(1.5%vs.5.1%),multi-organ failure(1.5%vs.7.1%),and local pain(0 vs 4%).The main categories of substances involved were psychiatric medications(23.1%),sedatives(20.5%),insecticides(13.8%),and herbicides(12.8%).CONCLUSION:The clinical manifestations of acute poisoning in patients with an uncertain exposure history are diverse and nonspecific,and toxicological analysis plays a pivotal role in the diagnosis and differential diagnosis of such patients.展开更多
Nuclear astrophysics is a rapidly developing interdisciplinary feld of research that has received extensive attention from the scientifc community since the midtwentieth century.Broadly,it uses the laws of extremely s...Nuclear astrophysics is a rapidly developing interdisciplinary feld of research that has received extensive attention from the scientifc community since the midtwentieth century.Broadly,it uses the laws of extremely small atomic nuclei to explain the evolution of the universe.Owing to the complexity of nucleosynthesis processes and our limited understanding of nuclear physics in astrophysical environments,several critical astrophysical problems remain unsolved.To achieve a better understanding of astrophysics,it is necessary to measure the cross sections of key nuclear reactions with the precision required by astrophysical models.Direct measurement of nuclear reaction cross sections is an important method of investigating how nuclear reactions infuence stellar evolution.Given the challenges involved in measuring the extremely low crosssections of nuclear reactions in the Gamow peak and preparing radioactive targets,indirect methods,such as the transfer reaction,coulomb dissociation,and surrogate ratio methods,have been developed over the past several decades.These are powerful tools in the investigation of,for example,neutron-capture(n,r)reactions with short-lived radioactive isotopes.However,direct measurement is still preferable,such as in the case of reactions involving light and stable nuclei.As an essential part of stellar evolution,these low-energy stable nuclear reactions have been of particular interest in recent years.To overcome the diffculties in measurements near or deeply within the Gamow window,the combination of an underground laboratory and high-exposure accelerator/detector complex is currently the optimal solution.Therefore,underground experiments have emerged as a new and promising direction of research.In addition,to better simulate the stellar environment in the laboratory,research on nuclear physics under laser-driven plasma conditions has gradually become a frontier hotspot.In recent years,the CIAE team conducted a series of distinctive nuclear astrophysics studies,relying on the Jinping Underground Nuclear Astrophysics platform and accelerators in Earth’s surface laboratories,including the Beijing Radioactive Ion beam Facility,as well as other scientifc platforms at home and abroad.This research covered nuclear theories,numerical models,direct measurements,indirect measurements,and other novel approaches,achieving great interdisciplinary research results,with high-level academic publications and signifcant international impacts.This article reviews the above research and predicts future developments.展开更多
The compaction quality of subgrade filler strongly affects subgrade settlement.The main objective of this research is to analyze the macro-and micro-mechanical compaction characteristics of subgrade filler based on th...The compaction quality of subgrade filler strongly affects subgrade settlement.The main objective of this research is to analyze the macro-and micro-mechanical compaction characteristics of subgrade filler based on the real shape of coarse particles.First,an improved Viola-Jones algorithm is employed to establish a digitalized 2D particle database for coarse particle shape evaluation and discrete modeling purposes of subgrade filler.Shape indexes of 2D subgrade filler are then computed and statistically analyzed.Finally,numerical simulations are performed to quantitatively investigate the effects of the aspect ratio(AR)and interparticle friction coefficient(μ)on the macro-and micro-mechanical compaction characteristics of subgrade filler based on the discrete element method(DEM).The results show that with the increasing AR,the coarse particles are narrower,leading to the increasing movement of fine particles during compaction,which indicates that it is difficult for slender coarse particles to inhibit the migration of fine particles.Moreover,the average displacement of particles is strongly influenced by the AR,indicating that their occlusion under power relies on particle shapes.The dis-placement and velocity of fine particles are much greater than those of the coarse particles,which shows that compaction is primarily a migration of fine particles.Under the cyclic load,the interparticle friction coefficientμhas little effect on the internal structure of the sample;under the quasi-static loads,however,the increase inμwill lead to a significant increase in the porosity of the sample.This study could not only provide a novel approach to investigate the compaction mechanism but also establish a new theoretical basis for the evaluation of intelligent subgrade compaction.展开更多
基金supported by the National Key R&D Program of China(2021YFF1200602)the National Science Fund for Excellent Overseas Scholars(0401260011)+3 种基金the National Defense Science and Technology Innovation Fund of Chinese Academy of Sciences(c02022088)the Tianjin Science and Technology Program(20JCZDJC00810)the National Natural Science Foundation of China(82202798)the Shanghai Sailing Program(22YF1404200).
文摘Brain-computer interfaces(BCIs)represent an emerging technology that facilitates direct communication between the brain and external devices.In recent years,numerous review articles have explored various aspects of BCIs,including their fundamental principles,technical advancements,and applications in specific domains.However,these reviews often focus on signal processing,hardware development,or limited applications such as motor rehabilitation or communication.This paper aims to offer a comprehensive review of recent electroencephalogram(EEG)-based BCI applications in the medical field across 8 critical areas,encompassing rehabilitation,daily communication,epilepsy,cerebral resuscitation,sleep,neurodegenerative diseases,anesthesiology,and emotion recognition.Moreover,the current challenges and future trends of BCIs were also discussed,including personal privacy and ethical concerns,network security vulnerabilities,safety issues,and biocompatibility.
文摘BACKGROUND Antimicrobial resistance(AMR)is an escalating global health threat,disproportionately impacting low-income and middle-income countries like India.The rise of multidrug-resistant organisms(MDROs)complicates treatment,increases healthcare costs,and contributes to higher morbidity and mortality.In India,factors such as antibiotic misuse,over-the-counter availability,and self-medication have exacerbated this crisis.Despite the urgency,regional data on MDRO prevalence remains limited.AIM To assess the burden and distribution of MDRO infections identified at a tertiary healthcare institute in North India.METHODS This cross-sectional study analyzed inpatient data from All India Institute of Medical Sciences(AIIMS)Rishikesh using the E-hospital database from May 2021 to February 2024,except 2022.All inpatients with culture-confirmed MDRO infections were included.Patient charts and discharge summaries were reviewed.Data analysis was performed using Jamovi software,with descriptive statistics summarizing demographics.Theχ²test was used to assess associations between MDROs and various factors.Ethical approval was obtained,and patient confidentiality was maintained.RESULTS This study included 820 participants having 1106 MDROs.The majority of patients were aged 35-64 years,with a male predominance(57.6%).Most cases were from Uttar Pradesh(49.1%)and Uttarakhand(47.6%),with Bijnor and Haridwar districts reporting the highest burden from their respective states.Klebsiella pneumoniae(K.pneumoniae)(30.6%),Acinetobacter baumannii(16.7%),and Escherichia coli(E.coli)(16.7%)were the most common MDROs.Urine was the most frequent sample type(51.0%),with K.pneumoniae as the leading pathogen.Infections varied significantly across departments(P<0.001),with General Medicine and Surgery reporting the highest burden.E.coli and Klebsiella spp.were most prevalent in these departments respectively.MDRO prevalence fluctuated over time,with significant variations by quarter(P<0.001).Following the second coronavirus disease 2019 wave,there was a rapid surge in MDROs,which stabilized after approximately three months.The overall mortality among patients harboring MDROs was 25.9%.CONCLUSION This study highlights the burden of MDROs among patients at AIIMS Rishikesh,with K.pneumoniae as the predominant pathogen.Strengthening antimicrobial stewardship and infection control measures is essential to combat rising AMR,with department-specific,and pathogen-specific stewardships.
基金Chongqing Institute of Engineering School-level Project:Research on Urban Waterfront Landscape Design Based on the Concept of River Ecological Restoration-Taking the Section of Chongqing Institute of Engineering on Huaxi River as an Example(Project No.:2022xskz02)。
文摘Since the reform and opening up,the development approach targeting urban economic growth has led to a sharp increase in the proportion of impervious hardened surfaces in cities and significant waste of natural resources.The urgent need for water ecological civilization construction is of great significance to the continuation of human civilization in the long run.This paper focuses on the urban waterfront landscape design of the Chongqing Institute of Engineering section of the Huaxi River in Banan District,emphasizing the concept of“symbiosis”.Using site cultural symbols as a medium to connect the campus and the city on both sides of the river,returning the riverbank to the people,restoring the ecological space of the riverfront,enriching the landscape belt,promoting the protection of bird and fish habitats,and stimulating the vitality of the riverbank space;it aims to pave the way for ecological restoration,functional expansion,landscape renewal,and riverfront space activation at the study site.
基金supported by the Foundation of Shanwei Institute of Technology(swjy23-008).
文摘The software technology field is facing new talent demands brought by the Information Technology Application Innovation(ITAI)industry.This paper takes Shanwei Institute of Technology as an example to deeply explore the construction of a school-enterprise community education model driven by the ITAI industry.It establishes the Kirin Workshop training base to facilitate talent cultivation,integrates the ITAI Application Adaptation Center to enhance technical capabilities,cooperates with Liqi Technology to establish an industrial college for government talent training,adjusts the professional curriculum system,and arranges for students to participate in ITAI vocational skills competitions.The school-enterprise collaborative cultivation mechanism meets the talent needs of the ITAI field,with effective practical results.This paper also points out the shortcomings of the school-enterprise collaborative education model in the ITAI industry and provides optimization methods to explore new paths for industry-education integration and serve the development of regional and national ITAI industries^([1]).
文摘Introduction: Malignant sylvian infarction (MSI) is a type of ischemic stroke (ICS) usually affecting the entire territory of the middle cerebral artery (MCA) associated with significant cerebral edema and a mass. It represents about 10% of all AICs, with a mortality of up to 80%. The objectives of our study were to describe the sociodemographic profile and the main clinical manifestations and identify the prognostic factors of ISM. Material and Methods: We conducted a retrospective descriptive study over a 2-year period. It included patients hospitalized for cerebral infarction involving 2/3 of the ACM territory with a NIHSS score ≥ 17 and/or a Glasgow score Results: We collected 223 patients hospitalized for ischemic stroke, of whom 21 patients (9.4%) presented with ISM. The mean age was 57.43 ± 24.24 years with a male predominance (52.4%). The mean admission time was 47 ± 0.87 hours, and hemiplegia was the frequent neurological sign (85.7%). HBP was the common cardiovascular risk factor (76.2%). The mean NIHSS at admission was 18.38 ± 12.29. Respiratory distress (p-value = 0.00015), aspiration pneumonia (p-value = 0.015) and brain herniation (p-value = 0.014) were the main complications associated with mortality. Conclusion: ISM is associated with poor prognosis in the absence of surgical treatment. Respiratory distress, aspiration pneumonia and brain herniation are associated with high mortality.
基金supported by Continuous-Support Basic Scientific Research Project(No.BJ010261223282)the National Natural Science Foundation of China(Nos.U2167201,11975318)+2 种基金the State Key Laboratory of Nuclear Physics and TechnologyPeking University(No.NPT2023KFY01)the Research and Development Project of China National Nuclear Corporation。
文摘The prompt fission neutron spectrum(PFNS)is a key nuclear data quantity that is of particular interest and plays a crucial role in understanding and modeling fission processes.An array comprising 48 liquid scintillation detectors and a parallelplate avalanche counter(PPAC)was developed at the China Institute of Atomic Energy(CIAE)to measure the PFNS of actinide nuclei.Efficiency and energy calibrations were performed for all the liquid scintillators,and their efficiencies were consistently found to be better than 5%.The time resolutions of the PPAC and liquid scintillators were measured to be 1.08 ns and 1.16 ns using~(252)Cf and~(207)Bi sources,respectively.The pulse shape discrimination of the liquid scintillator was utilized to identify neutron andγsignals on an event-by-event basis,and the figure of merit was deduced as 1.12 at a 200 ke Vee threshold.The contribution to the PFNS from multiple scattered neutrons was evaluated via Geant4 simulations,and those originating from the environment were found to be comparable to the crosstalk between the detectors.The neutron efficiency of the entire detection array was calibrated using a~(252)Cf spontaneous fission source and was demonstrated to be consistent with the Geant4 simulation results,which verified the reliability of the detection array.
基金2024 University-level Innovation and Entrepreneurship Educational Reform Project,“Research on the Innovation and Entrepreneurship Education Model of Higher Vocational Colleges Based on the Theory of Technological Innovation Diffusion”(Project No.:CYJG202414)Academic Year Higher Education Institution Graduate Employment and Entrepreneurship Research Project,“Research on Strategies for Cultivating Innovation and Entrepreneurship Abilities Among Graduates of Higher Vocational Colleges”(Project No.:GJXY2024N083)2024 Guangdong Province General Higher Education Institution Specialized Innovation Project,“Research on a Specialized-Entrepreneurial Integration Talent Development System Guided by Core Competencies in the Era of Artificial Intelligence”(Project No.:2024WTSCX339)。
文摘Addressing the core weaknesses in the innovation and entrepreneurship capabilities of vocational college graduates,such as market insight and risk tolerance,as well as issues with the existing training model,including courses that are disconnected from industry,a lack of systematic practical training,and superficial school-enterprise cooperation,this paper constructs a“three-dimensional,four-dimensional”training system.The“three-dimensional”foundational framework encompasses three pillars:curriculum,general education layer,professional integration layer,practical application layer,practice as in three stages:introductory,simulated,and practical,and support including dual mentors,policies,and platforms.The“four-dimensional”differentiated strategies include four implementation pathways:professional differentiation,stage differentiation,addressing capability shortcomings,and school-government-industry collaboration.This system is grounded in theories such as multiple intelligences theory and systems theory,forming a closed-loop process of“theoretical input—practical application—support mechanisms”.Based on the practices of Guangdong Vocational Institute of Public Administration,the paper proposes a competency development pathway tailored by major and stage,which can effectively enhance the innovative and entrepreneurial core competencies of vocational college graduates.This provides a replicable systematic solution for vocational college innovative and entrepreneurial education,supporting vocational education reform and regional economic development.
基金supported in part by the Education Reform Key Projects of Heilongjiang Province under Grant Nos.SJGZ20220011,SJGZ20220012,and SJGZY2024008。
文摘In response to the current issues in the construction of software engineering(SE)degree granting program,such as insufficient resource integration,low level of internationalization,and inadequate quality control,we propose the Software Engineering Degree Granting Program Construction Practice Project at Harbin Institute of Technology(HIT).This project aims to explore new models for software talent cultivation,establish a superior SE degree granting program,and ultimately cultivate outstanding internationalized composite SE professionals to support the high-quality development of the national software industry.To this end,we design a distinctive overall construction idea and plan for the SE degree granting program,which are characterized by“3I3S:three highlights for specialized cultivation and strictness in three aspects to ensure quality control”.After years of practice and validation of the project at the School of Software at HIT,this project has proven effective in optimizing talent cultivation models,enhancing students’practical abilities,promoting international exchange and cooperation,advancing industry-education integration,and meeting industrial needs.
文摘Irrigation service defines the responsibilities and rights of irrigation system management agencies,water users,and other parties involved in the irrigation service contract.As a result,the irrigation service must be clearly specified and updated by crop seasons and by all partners.Given the inherent complexity of the service,this article presents and discusses the development and application of a computer model designed to support the specification of public service levels in rice-based irrigation systems.Applied to the Tu Mai irrigation system,the model has enabled all involved parties to define irrigation service levels through systematic analysis and a thorough consideration of constraints such as water resource characteristics,hydraulic structures,and the operational plans of the irrigation system.The research findings have also helped relevant agencies reach agreements on irrigation service levels for the particular irrigation season of spring 2023,which included one irrigation period for land preparation and five subsequent irrigation periods for rice crops corresponding with a specific schedule for operating the system(discharges and duration)that met the farmers’requests for their farming practices and reduced the loss due to rice crop yield decline at the irrigation system as a whole.Additionally,recommendations for improving irrigation services in the Tu Mai system have been made,including upgrading the head pumping station to accommodate lower water levels in the Cau River,aligning the irrigation schedules of the Water User Associations(WUAs)more flexibly,and strictly supervising water deliveries to ensure safety and fairness.
文摘Traditional psychological treatment methods often require a long time and have limited effects.Researchers have begun to explore the combination of brain-computer interface(BCI)technology and mental health,providing new possibilities for the treatment and rehabilitation of mental illnesses.This paper reviews the advantages,existing risks,and challenges of BCI technology in mental health treatment,and prospects the future development of research on BCI and mental health.
文摘Introduction: Pain has been defined for more than 20 years by the International Association for the Study of Pain (IASP) as an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage. It has been recognized as a feature of Parkinson’s disease (PD) since the first descriptions of the disease. Material and Methods: This was a prospective descriptive study lasting six (06) months from November 1, 2023 to April 30, 2024. We included all patients diagnosed with PD and who had pain. Sociodemographic, clinical, paraclinical and therapeutic data were evaluated for each patient. Results: We identified a sample of 62 Parkinson’s patients, of whom 52 patients or 85.2% had associated pain. We noted a male predominance (38M/14F) and a sex ratio of 2.71. Musculoskeletal pain was common in 80% of our respondents. WHO level I, antidepressants and background treatment for KD were the most prescribed molecules. Conclusion: Our study shows a frequency of pain in PD. However, musculoskeletal pain is the most frequently encountered type of pain in PD patients. WHO step I analgesics, antidepressants and background treatment of KD were the main prescriptions in our study.
基金supported by the National Key R&D Program of China(2022YFA1203304)the National Natural Science Foundation of China(52473270 and T2422028)+1 种基金the Suzhou Institute of Nano-Tech and Nano-Bionics,Chinese Academy of Sciences(start-up grant E1552102)the Key Research and Development Program of Gansu Province-Industrial Project(No.25YFGA044).
文摘The advancement of fibre electronics is crucial for developing wearable smart textiles.However,traditional single-function fibres are typically limited to basic sensing and data collection capabilities,lacking effective computational and multimodal signal processing abilities,thus significantly restricting their potential in human activity recognition.Recently,Gupta et al.introduced an innovative single-fibre computer embedding eight microelectronic devices,integrating sensing,communication,and computation into a single fibre.Establishing a distributed cooperative fibre network substantially enhanced human activity recognition accuracy from 67%(single-fibre scenario)to 95%.This novel approach effectively addresses the limitations of conventional smart fibres,paving the way for multi-point sensing,edge-based inference,and realtime human-computer interactions in future intelligent textiles.
文摘Purpose:Interdisciplinary research has become a critical approach to addressing complex societal,economic,technological,and environmental challenges,driving innovation and integrating scientific knowledge.While interdisciplinarity indicators are widely used to evaluate research performance,the impact of classification granularity on these assessments remains underexplored.Design/methodology/approach:This study investigates how different levels of classification granularity-macro,meso,and micro-affect the evaluation of interdisciplinarity in research institutes.Using a dataset of 262 institutes from four major German non-university organizations(FHG,HGF,MPG,WGL)from 2018 to 2022,we examine inconsistencies in interdisciplinarity across levels,analyze ranking changes,and explore the influence of institutional fields and research focus(applied vs.basic).Findings:Our findings reveal significant inconsistencies in interdisciplinarity across classification levels,with rankings varying substantially.Notably,the Fraunhofer Society(FHG),which performs well at the macro level,experiences significant ranking declines at meso and micro levels.Normalizing interdisciplinarity by research field confirmed that these declines persist.The research focus of institutes,whether applied,basic,or mixed,does not significantly explain the observed ranking dynamics.Research limitations:This study has only considered the publication-based dimension of institutional interdisciplinarity and has not explored other aspects.Practical implications:The findings provide insights for policymakers,research managers,and scholars to better interpret interdisciplinarity metrics and support interdisciplinary research effectively.Originality/value:This study underscores the critical role of classification granularity in interdisciplinarity assessment and emphasizes the need for standardized approaches to ensure robust and fair evaluations.
基金funded by the Shanghai Philosophy and Social Science Planning Project (2021BZX008)the National Social Science Foundation of China (23BZX110)the National Office for Philosophy and Social Science (20&ZD045).
文摘Background Clinical brain-computer interface(BCI)for mental disorders is an emerging interdisciplinary research field,posing new ethical concerns and challenges,yet lacking practical ethical governance guidelines for stakeholders and the entire community.Aims This study aims to establish a multidisciplinary consensus of principles for ethical governance of clinical BCI research for mental disorders and offer practical ethical guidance to stakeholders involved.Methods A systematic literature review,symposium and roundtable discussions,and a pre-Delphi(round 0)survey were conducted to form the questionnaire for the three-round modified Delphi study.Two rounds of surveys,followed by a third round of independent interviews of 25 experts from BCI-related research domains,were involved.We conducted quantitative analysis of responses and agreements among experts to reveal the consensus and differences regarding the ethical governance of mental BCI research from a multidisciplinary perspective.Results The Delphi panel emphasised important concerns of ethical review practices and ethical principles within the BCI context,identified qualified and highly influential institutions and personnel in conducting and advancing clinical BCI research,and recognised prioritised aspects in the risk-benefit evaluation.Experts expressed diverse opinions on specific ethical concerns,including concerns about invasive technology,its impact on humanity and potential social consequences.Agreement was reached that the practices of ethical governance of clinical BCI for mental disorders should focus on patient voluntariness,autonomy,long-term effects and related assessments of BCI interventions,as well as privacy protection,transparent reporting and ensuring that the research is conducted in qualified institutions with strong data security.Conclusions Ethical governance of clinical research on BCI for mental disorders should include interdisciplinary experts to balance various needs and incorporate the expertise of different stakeholders to avoid serious ethical issues.It requires scientifically grounded approaches,continuous monitoring and interdisciplinary collaboration to ensure evidence-based policies,comprehensive risk assessments and transparency,thereby promoting responsible innovations and protecting patient rights and well-being.
基金Funded by the Science and Technology Fund of Jiangxi Provincial Department of Education(No.GJJ2201105)the Innovation Fund Designated for Graduate Students of Jiangxi Province(No.YC2023-S733)。
文摘We selected a cell with superior electrochemical performance to characterization microstructure characterization.Here,we employed high-resolution SEM and X-ray nano-CT to investigate a porous LSCrRu-GDC composite anode.These experimental results are utilized for characterize and quantify the key structural parameters,such as the volume ratio of the three phases(LSCrRu,GDC,and pore),connected porosity,tortuosity,surface area of each phase,interface of LSCrRu/GDC,and three-phase boundary length(TPB where the LSCrRu,GDC and fuel gas phases come together)of the anode.
基金financial support of the Fundamental Research Funds for the Central Universities(SCU2023HGXY)Special Research Funds for Intelligent Battery Cell Multidimensional Signal Sensing Technology Project from Huawei Technologies Co.Ltd.(24H1117)。
文摘Accurate estimation on the state of health(SOH)is essential for ensuring the safe and reliable operation of batteries.Traditional assessment methods primarily focus on electrical attributes for capacity decay,often overlooking the impact of thermal distribution on battery aging.However,thermal effect is a critical factor for degradation process and associated risks throughout their service life.In this paper,we introduce a novel deep learning framework specially designed to estimate the capacity and thermal risks of lithium-ion batteries(LIBs).This model consists of two main components that leverage computer vision technology.One predicts battery capacity by integrating the advantages of thermal and electrical features using a temporal pattern attention(TPA)mechanism,while the other assesses thermal risk by incorporating temperature variation to provide early warnings of potential hazards.An infrared camera is deployed to record temperature evolution of LIBs during the electrochemical process.The thermal heterogeneities are recorded by infrared camera,and the corresponding temperature evolutions are extracted as representative features for analysis.The proposed model demonstrates high accuracy and stability,with an average root mean square error(RMSE)of 0.67% for capacity estimation and accuracy exceeding 93.9% for risk prediction,underscoring the importance of integrating spatial temperature distribution into battery health assessments.This work offers valuable insights for the development of intelligent and robust battery management systems.
文摘Introduction: Vitamin D plays a key role in phosphocalcic metabolism, in normal functioning of the immune system and in the prevention of certain forms of cancer. Systematic vitamin D supplementation has been implemented in most Western countries, which has drastically reduced the prevalence of rickets. In Senegal, a country with enough sunshine, no large-scale data exists on vitamin D deficiency in children. In addition, there are no guidelines from the Ministry of Health and Social Action (MoHSA) on vitamin D supplementation. Our objective was to determine the prevalence of vitamin D deficiency in children aged 6 to 59 months and to analyze the factors associated with it at the Institute of Social Pediatrics in Pikine-Guédiawaye, a suburb of Dakar. Patients and Methods: This was a prospective, descriptive and analytical cross-sectional study over a 3-month period (from January to March 2024) at the Institute of Social Pediatric (IPS) of Pikine-Guédiawaye. The study population consisted of all children aged 6 to 59 months free from any acute or chronic pathology, whose parents had agreed to answer the questionnaires after having consented and signed the consent and children who had had a sample taken for vitamin D dosage. Results: We included 102 children, 35 of whom had vitamin D deficiency, i.e. a prevalence of 34.31% with a slight male predominance (sex ratio 1.05). Infants aged 13 - 24 months were more affected (41.67%), but the difference was not statistically significant (p-value = 0.385). Patients with acute malnutrition had a significantly higher prevalence of vitamin D deficiency (54.17% of cases versus 28.38%) in those without acute malnutrition (p = 0.02). On the other hand, chronic malnutrition, underweight and diversification foods were not significantly associated with vitamin D deficiency (p of 0.60, 0.42 and 0.09 respectively). Conclusion: Vitamin deficiency affects one-third of apparently healthy children under 5 and this deficiency has no significant relationship with diversification foods. This suggests that the observed vitamin D deficiencies are less related to diet than to lack of sun exposure.
基金supported by National Natural Science Foundation of China(82172184)。
文摘BACKGROUND:In clinical practice,some patients might not be able or unwilling to provide a thorough history of medication and poison exposure.The aim of this study was to use toxicological analysis to examine the clinical characteristics of patients with acute poisoning whose exposure history was uncertain from a toxicological analysis perspective.METHODS:This was a retrospective and descriptive study from an institute of poisoning.Patient registration information and test reports spanning the period from April 1,2020 to March 31,2022,were obtained.Patients with uncertain exposure histories and who underwent toxicological analysis were included.Clinical manifestations and categories of toxics were analyzed.RESULTS:Among the 195 patients with positive toxicological analysis results,the main causes of uncertain exposure history was disturbance of consciousness(62.6%),unawareness(23.6%)and unwillingness or lack of cooperation(13.8%).The predominant clinical manifestations were disturbed consciousness(62.6%),followed by vomiting and nausea(14.4%)and liver function abnormalities(8.7%).A comparison of clinical manifestations between patients with positive and negative(n=99)toxicological analyses results revealed significantly different proportions of disturbances in consciousness(63%vs.21%),dizziness(1.5%vs.5.1%),multi-organ failure(1.5%vs.7.1%),and local pain(0 vs 4%).The main categories of substances involved were psychiatric medications(23.1%),sedatives(20.5%),insecticides(13.8%),and herbicides(12.8%).CONCLUSION:The clinical manifestations of acute poisoning in patients with an uncertain exposure history are diverse and nonspecific,and toxicological analysis plays a pivotal role in the diagnosis and differential diagnosis of such patients.
基金National Natural Science Foundation of China(Nos.12435010)National Key R&D Program of China(No.2022YFA1602301)。
文摘Nuclear astrophysics is a rapidly developing interdisciplinary feld of research that has received extensive attention from the scientifc community since the midtwentieth century.Broadly,it uses the laws of extremely small atomic nuclei to explain the evolution of the universe.Owing to the complexity of nucleosynthesis processes and our limited understanding of nuclear physics in astrophysical environments,several critical astrophysical problems remain unsolved.To achieve a better understanding of astrophysics,it is necessary to measure the cross sections of key nuclear reactions with the precision required by astrophysical models.Direct measurement of nuclear reaction cross sections is an important method of investigating how nuclear reactions infuence stellar evolution.Given the challenges involved in measuring the extremely low crosssections of nuclear reactions in the Gamow peak and preparing radioactive targets,indirect methods,such as the transfer reaction,coulomb dissociation,and surrogate ratio methods,have been developed over the past several decades.These are powerful tools in the investigation of,for example,neutron-capture(n,r)reactions with short-lived radioactive isotopes.However,direct measurement is still preferable,such as in the case of reactions involving light and stable nuclei.As an essential part of stellar evolution,these low-energy stable nuclear reactions have been of particular interest in recent years.To overcome the diffculties in measurements near or deeply within the Gamow window,the combination of an underground laboratory and high-exposure accelerator/detector complex is currently the optimal solution.Therefore,underground experiments have emerged as a new and promising direction of research.In addition,to better simulate the stellar environment in the laboratory,research on nuclear physics under laser-driven plasma conditions has gradually become a frontier hotspot.In recent years,the CIAE team conducted a series of distinctive nuclear astrophysics studies,relying on the Jinping Underground Nuclear Astrophysics platform and accelerators in Earth’s surface laboratories,including the Beijing Radioactive Ion beam Facility,as well as other scientifc platforms at home and abroad.This research covered nuclear theories,numerical models,direct measurements,indirect measurements,and other novel approaches,achieving great interdisciplinary research results,with high-level academic publications and signifcant international impacts.This article reviews the above research and predicts future developments.
基金This work was supported by the National Key R&D Program‘Transportation Infrastructure’project(No.2022YFB2603400).
文摘The compaction quality of subgrade filler strongly affects subgrade settlement.The main objective of this research is to analyze the macro-and micro-mechanical compaction characteristics of subgrade filler based on the real shape of coarse particles.First,an improved Viola-Jones algorithm is employed to establish a digitalized 2D particle database for coarse particle shape evaluation and discrete modeling purposes of subgrade filler.Shape indexes of 2D subgrade filler are then computed and statistically analyzed.Finally,numerical simulations are performed to quantitatively investigate the effects of the aspect ratio(AR)and interparticle friction coefficient(μ)on the macro-and micro-mechanical compaction characteristics of subgrade filler based on the discrete element method(DEM).The results show that with the increasing AR,the coarse particles are narrower,leading to the increasing movement of fine particles during compaction,which indicates that it is difficult for slender coarse particles to inhibit the migration of fine particles.Moreover,the average displacement of particles is strongly influenced by the AR,indicating that their occlusion under power relies on particle shapes.The dis-placement and velocity of fine particles are much greater than those of the coarse particles,which shows that compaction is primarily a migration of fine particles.Under the cyclic load,the interparticle friction coefficientμhas little effect on the internal structure of the sample;under the quasi-static loads,however,the increase inμwill lead to a significant increase in the porosity of the sample.This study could not only provide a novel approach to investigate the compaction mechanism but also establish a new theoretical basis for the evaluation of intelligent subgrade compaction.
