This study focuses on the improvement of the thermal stability and flame-retardant performance of polyurethane(PU)foam by using effective flame-retardant additives and nano silica(nSiO_(2))particles from rice husk.The...This study focuses on the improvement of the thermal stability and flame-retardant performance of polyurethane(PU)foam by using effective flame-retardant additives and nano silica(nSiO_(2))particles from rice husk.The addition of non-halogen flame retardants(FRs)including aluminum trihydroxide(ATH),triphenyl phosphate(TPP),and diammonium phosphate(DAP)leads to markedly enhanced thermal sta-bility and fire resistance of the PU/nSiO_(2)/FRs nanocomposites,resulting in achieving UL-94 HB standard.In particular,the nanocomposites met the UL-94 V-0 criteria thanks to the inclusion of DAP at 25 phr.The LOI value of the nanocomposites reached 26%which is much higher than that of PU/nSiO_(2)nanocompos-ite,about 20%.In order to further understand the fire-proof mechanism,the residue char layer remaining of the PU/nSiO_(2)/FRs nanocomposites after being burned was also investigated by scanning electron mi-croscopy(SEM)and Fourier transform infrared(FTIR).In addition,the microstructure,thermal stability,thermal conductivity,and mechanical properties of nanocomposites were also evaluated in this study.展开更多
The dual role of reactive oxygen and nitrogen species(RONS)in physiological and pathological processes in biological systems has been widely reported.It has been recently suggested that the regulation of RONS levels u...The dual role of reactive oxygen and nitrogen species(RONS)in physiological and pathological processes in biological systems has been widely reported.It has been recently suggested that the regulation of RONS levels under physiological and pathological conditions is a potential therapy to promote health and treat diseases,respectively.Injectable hydrogels have been emerging as promising biomaterials for RONS-related biomedical applications owing to their excellent biocompatibility,three-dimensional and extracellular matrix-mimicking structures,tunable properties and easy functionalization.These hydrogels have been developed as advanced injectable platforms for locally generating or scavenging RONS,depending on the specific conditions of the target disease.In this review article,the design principles and mechanism by which RONS are generated/scavenged from hydrogels are outlined alongside a discussion of their in vitro and in vivo evaluations.Additionally,we highlight the advantages and recent developments of these injectable RONS-controlling hydrogels for regenerativemedicines and tissue engineering applications.展开更多
基金funded by the Vietnam National University Ho Chi Minh City(VNU-HCM)under grant number C2022-18-41.
文摘This study focuses on the improvement of the thermal stability and flame-retardant performance of polyurethane(PU)foam by using effective flame-retardant additives and nano silica(nSiO_(2))particles from rice husk.The addition of non-halogen flame retardants(FRs)including aluminum trihydroxide(ATH),triphenyl phosphate(TPP),and diammonium phosphate(DAP)leads to markedly enhanced thermal sta-bility and fire resistance of the PU/nSiO_(2)/FRs nanocomposites,resulting in achieving UL-94 HB standard.In particular,the nanocomposites met the UL-94 V-0 criteria thanks to the inclusion of DAP at 25 phr.The LOI value of the nanocomposites reached 26%which is much higher than that of PU/nSiO_(2)nanocompos-ite,about 20%.In order to further understand the fire-proof mechanism,the residue char layer remaining of the PU/nSiO_(2)/FRs nanocomposites after being burned was also investigated by scanning electron mi-croscopy(SEM)and Fourier transform infrared(FTIR).In addition,the microstructure,thermal stability,thermal conductivity,and mechanical properties of nanocomposites were also evaluated in this study.
基金supported by a grant from Priority Research Centers Program(2019R1A6A1A11051471)funded by the National Research Foundation of Korea(NRF)and Korea Medical Device Development Fund grant funded by the Korea government(the Ministry of Science and ICT,the Ministry of Trade,Industry and Energy,the Ministry of Health&Welfare and the Ministry of Food and Drug Safety)(Project Number:RS-2020-KD000033)Korea Evaluation Institute of Industrial Technology(KEIT 20018560,NTIS 1415180625)funded by the Ministry of Trade,Industry&Energy(MOTIE,Korea).
文摘The dual role of reactive oxygen and nitrogen species(RONS)in physiological and pathological processes in biological systems has been widely reported.It has been recently suggested that the regulation of RONS levels under physiological and pathological conditions is a potential therapy to promote health and treat diseases,respectively.Injectable hydrogels have been emerging as promising biomaterials for RONS-related biomedical applications owing to their excellent biocompatibility,three-dimensional and extracellular matrix-mimicking structures,tunable properties and easy functionalization.These hydrogels have been developed as advanced injectable platforms for locally generating or scavenging RONS,depending on the specific conditions of the target disease.In this review article,the design principles and mechanism by which RONS are generated/scavenged from hydrogels are outlined alongside a discussion of their in vitro and in vivo evaluations.Additionally,we highlight the advantages and recent developments of these injectable RONS-controlling hydrogels for regenerativemedicines and tissue engineering applications.
