In recent years,the significant growth in the Internet of Things(IoT)technology has brought a lot of attention to information and communication industry.Various IoT paradigms like the Internet of Vehicle Things(IoVT)a...In recent years,the significant growth in the Internet of Things(IoT)technology has brought a lot of attention to information and communication industry.Various IoT paradigms like the Internet of Vehicle Things(IoVT)and the Internet of Health Things(IoHT)create massive volumes of data every day which consume a lot of bandwidth and storage.However,to process such large volumes of data,the existing cloud computing platforms offer limited resources due to their distance from IoT devices.Consequently,cloudcomputing systems produce intolerable latency problems for latency-sensitive real-time applications.Therefore,a newparadigm called fog computingmakes use of computing nodes in the form of mobile devices,which utilize and process the real-time IoT devices data in orders of milliseconds.This paper proposes workload-aware efficient resource allocation and load balancing in the fog-computing environment for the IoHT.The proposed algorithmic framework consists of the following components:task sequencing,dynamic resource allocation,and load balancing.We consider electrocardiography(ECG)sensors for patient’s critical tasks to achieve maximum load balancing among fog nodes and to measure the performance of end-to-end delay,energy,network consumption and average throughput.The proposed algorithm has been evaluated using the iFogSim tool,and results with the existing approach have been conducted.The experimental results exhibit that the proposed technique achieves a 45%decrease in delay,37%reduction in energy consumption,and 25%decrease in network bandwidth consumption compared to the existing studies.展开更多
The potential of the high resolution nuclear track detector (NTD) CR-39 is examined carefully for the measurement of relativistic nuclear projectile fragmentation cross sections and studies of related processes using ...The potential of the high resolution nuclear track detector (NTD) CR-39 is examined carefully for the measurement of relativistic nuclear projectile fragmentation cross sections and studies of related processes using the experience of many years of such measurements. The charge resolution and the charge resolving power of CR-39 detectors for the measurements of 158 A GeV 207Pb projectiles and their fragments are presented. Exposures of target-detector stacks, the chemical etching procedure and the nuclear track measurements are described in detail discussing precautions and possible errors. The procedures discussed are also valid for other NTDs. A comparison with electronic active detectors is also made considering important detection and measurement aspects. An experimental design proposing the co-use of NTDs with in-use active detectors is described.展开更多
Clear evidence exists for genetic susceptibility to hepatocellular carcinoma (HCC). Genome-wide association studies have identified multiple candidate susceptibility loci. These loci suggest that genetic variation in ...Clear evidence exists for genetic susceptibility to hepatocellular carcinoma (HCC). Genome-wide association studies have identified multiple candidate susceptibility loci. These loci suggest that genetic variation in the immune system may underpin HCC susceptibility. Genes for the antigen processing and presentation pathway have been observed to be significantly enriched across studies and the pathway is identified directly through genome-wide studies of variation using pathway methods. Detailed analysis of the pathway indicates both variation in the antigen presenting loci and in the antigen processing are different in cases in controls. Pathway analysis at the transcriptional level also shows difference between normal liver and liver in individuals with HCC. Assessing differences in the pathway may prove important in improving immune therapy for HCC and in identifying responders for immune checkpoint therapy.展开更多
基金This research is supported and funded by King Khalid University of Saudi Arabia under the Grant Number R.G.P.1/365/42。
文摘In recent years,the significant growth in the Internet of Things(IoT)technology has brought a lot of attention to information and communication industry.Various IoT paradigms like the Internet of Vehicle Things(IoVT)and the Internet of Health Things(IoHT)create massive volumes of data every day which consume a lot of bandwidth and storage.However,to process such large volumes of data,the existing cloud computing platforms offer limited resources due to their distance from IoT devices.Consequently,cloudcomputing systems produce intolerable latency problems for latency-sensitive real-time applications.Therefore,a newparadigm called fog computingmakes use of computing nodes in the form of mobile devices,which utilize and process the real-time IoT devices data in orders of milliseconds.This paper proposes workload-aware efficient resource allocation and load balancing in the fog-computing environment for the IoHT.The proposed algorithmic framework consists of the following components:task sequencing,dynamic resource allocation,and load balancing.We consider electrocardiography(ECG)sensors for patient’s critical tasks to achieve maximum load balancing among fog nodes and to measure the performance of end-to-end delay,energy,network consumption and average throughput.The proposed algorithm has been evaluated using the iFogSim tool,and results with the existing approach have been conducted.The experimental results exhibit that the proposed technique achieves a 45%decrease in delay,37%reduction in energy consumption,and 25%decrease in network bandwidth consumption compared to the existing studies.
文摘The potential of the high resolution nuclear track detector (NTD) CR-39 is examined carefully for the measurement of relativistic nuclear projectile fragmentation cross sections and studies of related processes using the experience of many years of such measurements. The charge resolution and the charge resolving power of CR-39 detectors for the measurements of 158 A GeV 207Pb projectiles and their fragments are presented. Exposures of target-detector stacks, the chemical etching procedure and the nuclear track measurements are described in detail discussing precautions and possible errors. The procedures discussed are also valid for other NTDs. A comparison with electronic active detectors is also made considering important detection and measurement aspects. An experimental design proposing the co-use of NTDs with in-use active detectors is described.
文摘Clear evidence exists for genetic susceptibility to hepatocellular carcinoma (HCC). Genome-wide association studies have identified multiple candidate susceptibility loci. These loci suggest that genetic variation in the immune system may underpin HCC susceptibility. Genes for the antigen processing and presentation pathway have been observed to be significantly enriched across studies and the pathway is identified directly through genome-wide studies of variation using pathway methods. Detailed analysis of the pathway indicates both variation in the antigen presenting loci and in the antigen processing are different in cases in controls. Pathway analysis at the transcriptional level also shows difference between normal liver and liver in individuals with HCC. Assessing differences in the pathway may prove important in improving immune therapy for HCC and in identifying responders for immune checkpoint therapy.
