Inf<span style="font-family:Verdana;">lation has </span><span style="font-family:Verdana;">a </span><span style="font-family:Verdana;">substantial impact on ...Inf<span style="font-family:Verdana;">lation has </span><span style="font-family:Verdana;">a </span><span style="font-family:Verdana;">substantial impact on an economy because it affects the financial value of money and stability in the economy. Government </span><span style="font-family:Verdana;">and non-govern</span><span style="font-family:Verdana;">- </span><span style="font-family:Verdana;">ment policies might be hindered due to the excessive rate of inflation. This paper aims to model and forecast inflation by the Box-Jenkins autoregressive integrated moving average (ARIMA) technique using annual time series data on inflation from 1987 to 2017 in Bangladesh. It is found that ARIMA (2, 1, 0) model is the best optimal to forecast inflation for a period of up to eight years. Graphical tools</span><span style="font-family:Verdana;">,</span><span style="font-family:Verdana;"> as well as theoretical tests such as Ljung-Box, Shapiro-Wilk, and runs tests have been used in the model diagnostics.</span>展开更多
A new covariate dependent zero-truncated bivariate Poisson model is proposed in this paper employing generalized linear model. A marginal-conditional approach is used to show the bivariate model. The proposed model wi...A new covariate dependent zero-truncated bivariate Poisson model is proposed in this paper employing generalized linear model. A marginal-conditional approach is used to show the bivariate model. The proposed model with estimation procedure and tests for goodness-of-fit and under (or over) dispersion are shown and applied to road safety data. Two correlated outcome variables considered in this study are number of cars involved in an accident and number of casualties for given number of cars.展开更多
Background and aims:Currently,treatment with oral direct-acting antivirals is recommended for all hepatitis C virus(HCV)-infected pediatric patients.The aim of this study was to evaluate the efficacy and safety of sof...Background and aims:Currently,treatment with oral direct-acting antivirals is recommended for all hepatitis C virus(HCV)-infected pediatric patients.The aim of this study was to evaluate the efficacy and safety of sofosbuvir and ribavirin combination ther apy for children and adolescents in Bangladesh who are living with chronic HCV in fection.Methods:An experimental study was performed from January 2021 to December 2022.HCV polymerase chain reaction(PCR)-positive thalassemic children,who were 6–18 years of age,were enrolled by consecutive non-probability sampling.Clinical features were recorded,and investigations were performed.All patients were initially treated with sofosbuvir(200 mg for 6-to 11-year-olds and 400 mg for 12-to 18-year-olds)and ribavirin(10–15 mg/kg/day)and were assessed clinically on a four-weekly basis,along with liver-function testing.The total duration of therapy was 24 weeks.HCV PCR was done at the end of treatment and 12 weeks after the completion of treatment to see the sustained virological response.Results:There were 26 cases in total,with a mean age of 9.26?2.82 years;14 were males(53.8%),and 12 females(46.2%).Twenty-five(96.15%)patients achieved a sustained virological response,and the end-of-treatment PCR was negative.One patient(3.85%)was a nonresponder even after 24 weeks of treatment.The medication was well received,with only four patients(15.3%)reporting headaches that were reported untreated.Conclusion:The combination of sofosbuvir and ribavirin is effective in treating chronic HCV infection and is not accompanied by any major negative side effects.展开更多
文摘Inf<span style="font-family:Verdana;">lation has </span><span style="font-family:Verdana;">a </span><span style="font-family:Verdana;">substantial impact on an economy because it affects the financial value of money and stability in the economy. Government </span><span style="font-family:Verdana;">and non-govern</span><span style="font-family:Verdana;">- </span><span style="font-family:Verdana;">ment policies might be hindered due to the excessive rate of inflation. This paper aims to model and forecast inflation by the Box-Jenkins autoregressive integrated moving average (ARIMA) technique using annual time series data on inflation from 1987 to 2017 in Bangladesh. It is found that ARIMA (2, 1, 0) model is the best optimal to forecast inflation for a period of up to eight years. Graphical tools</span><span style="font-family:Verdana;">,</span><span style="font-family:Verdana;"> as well as theoretical tests such as Ljung-Box, Shapiro-Wilk, and runs tests have been used in the model diagnostics.</span>
文摘A new covariate dependent zero-truncated bivariate Poisson model is proposed in this paper employing generalized linear model. A marginal-conditional approach is used to show the bivariate model. The proposed model with estimation procedure and tests for goodness-of-fit and under (or over) dispersion are shown and applied to road safety data. Two correlated outcome variables considered in this study are number of cars involved in an accident and number of casualties for given number of cars.
基金Ethical clearance was obtained from the ethical review committee of Bangladesh Shishu Hospital&Institute(No.Admin/1041/DSH/2021).
文摘Background and aims:Currently,treatment with oral direct-acting antivirals is recommended for all hepatitis C virus(HCV)-infected pediatric patients.The aim of this study was to evaluate the efficacy and safety of sofosbuvir and ribavirin combination ther apy for children and adolescents in Bangladesh who are living with chronic HCV in fection.Methods:An experimental study was performed from January 2021 to December 2022.HCV polymerase chain reaction(PCR)-positive thalassemic children,who were 6–18 years of age,were enrolled by consecutive non-probability sampling.Clinical features were recorded,and investigations were performed.All patients were initially treated with sofosbuvir(200 mg for 6-to 11-year-olds and 400 mg for 12-to 18-year-olds)and ribavirin(10–15 mg/kg/day)and were assessed clinically on a four-weekly basis,along with liver-function testing.The total duration of therapy was 24 weeks.HCV PCR was done at the end of treatment and 12 weeks after the completion of treatment to see the sustained virological response.Results:There were 26 cases in total,with a mean age of 9.26?2.82 years;14 were males(53.8%),and 12 females(46.2%).Twenty-five(96.15%)patients achieved a sustained virological response,and the end-of-treatment PCR was negative.One patient(3.85%)was a nonresponder even after 24 weeks of treatment.The medication was well received,with only four patients(15.3%)reporting headaches that were reported untreated.Conclusion:The combination of sofosbuvir and ribavirin is effective in treating chronic HCV infection and is not accompanied by any major negative side effects.
