Pulse pile-up is a problem in nuclear spectroscopy and nuclear reaction studies that occurs when two pulses overlap and distort each other,degrading the quality of energy and timing information.Different methods have ...Pulse pile-up is a problem in nuclear spectroscopy and nuclear reaction studies that occurs when two pulses overlap and distort each other,degrading the quality of energy and timing information.Different methods have been used for pile-up rejection,both digital and analogue,but some pile-up events may contain pulses of interest and need to be reconstructed.The paper proposes a new method for reconstructing pile-up events acquired with a neutron detector array(NEDA)using an one-dimensional convolutional autoencoder(1D-CAE).The datasets for training and testing the 1D-CAE are created from data acquired from the NEDA.The new pile-up signal reconstruction method is evaluated from the point of view of how similar the reconstructed signals are to the original ones.Furthermore,it is analysed considering the result of the neutron-gamma discrimination based on charge comparison,comparing the result obtained from original and reconstructed signals.展开更多
In this article,the dynamical model and trajectory tracking problem for a tilt-rotor unmanned aerial vehicle is tackled through linear Active Disturbance Rejection Control(ADRC)applied on the tangent linearized system...In this article,the dynamical model and trajectory tracking problem for a tilt-rotor unmanned aerial vehicle is tackled through linear Active Disturbance Rejection Control(ADRC)applied on the tangent linearized system.To apply the ADRC scheme,it is considered the subsystem without the Y-axis component,which is differentially flat and whose flat outputs are obtained using the Kronecker matrix.Numerical assessment using as system parameters the ones of a scale prototype is provided to show the effectiveness of the proposal leading to accurate tracking results using admissible control values for an experimental scenario.展开更多
In this article, we establish the route taken by the author, and his research group, to bring differential flatness to the realm of active disturbance rejection control （ADRC）. This avenue entitled： 1） generalized...In this article, we establish the route taken by the author, and his research group, to bring differential flatness to the realm of active disturbance rejection control （ADRC）. This avenue entitled： 1） generalized proportional integral observers （GPIO）, as natural state and disturbance observers for fiat systems, 2） generalized proportional integral （GPI） control, provided with extra integrations, to produce a modular controller known as flat filters （FF＇s） and, finally, 3） the establishing of an equivalence of observer based ADRC with FF＇s. The context is that of pure integration systems. The obtained controllers depend only on the order of the flat system and they are to be directly used on the basis of the available flat output signal in a universal, modular, fashion. The map is complemented with the relevant references where the intermediate techniques were illustrated and developed, over the years, in connection with laboratory experimental implementations.展开更多
Heat moving source models along with transient heat analysis by finite element method were used to determine weld thermal cycles and isothermal sections obtained from the application of a gas tungsten arc welding bead...Heat moving source models along with transient heat analysis by finite element method were used to determine weld thermal cycles and isothermal sections obtained from the application of a gas tungsten arc welding beads on Inconel 718 plates. Analytical (Rosenthal’s thick plate model) and finite element results show an acceptable approximation with the experimental weld thermal cycles. The isothermal sections determined by numerical simulation show a better approximation with the experimental welding profile for double-ellipse model heat distribution than Gauss model. To analyze the microstructural transformation produced by different cooling rates in the fusion and heat affected zones, Vickers microhardness measurements (profile and mapping representation) were conducted. A hardness decrement for the heat affected zone (~200 HV0.2) and fusion zone (~240 HV0.2) in comparison with base material (~350 HV0.2) was observed. This behavior has been attributed to the heterogeneous solubilization process of the γ″ phase (nickel matrix), which, according to the continuous-cooling-transformation curve, produced the Laves phase,δ and MC transition phases, generating a loss in hardness close to the fusion zone.展开更多
Carcinogenic process has been proposed to relay on the capacity to induce local tissue damage and proliferative repair. Liver has a great regeneration capacity and currently, most studies point towards the dominant ro...Carcinogenic process has been proposed to relay on the capacity to induce local tissue damage and proliferative repair. Liver has a great regeneration capacity and currently, most studies point towards the dominant role of hepatocytes in regeneration at all levels of liver damage. The most frequent liver cancer is hepatocellular carcinoma(HCC). Historical findings originally led to the idea that the cell of origin of HCC might be a progenitor cell. However, current linage tracing studies put the progenitor hypothesis of HCC origin into question. In agreement with their dominant role in liver regeneration, mature hepatocytes are emerging as the cell of origin of HCC, although, the specific hepatocyte subpopulation of origin is yet to be determined. The relationship between the cancer cell of origin(CCO) and cancer-propagating cells, known as hepatic cancer stem cell(HCSC) is unknown. It has been challenging to identify the definitive phenotypic marker of HCSC, probably due to the existence of different cancer stem cells(CSC) subpopulations with different functions within HCC. There is a dynamic interconversion among different CSCs, and between CSC and non-CSCs. Because of that, CSC-state is currently defined as a description of a highly adaptable and dynamic intrinsic property of tumor cells, instead of a static subpopulation of a tumor. Altered conditions could trigger the gain of stemness, some of them include: EMT-MET, epigenetics, microenvironment and selective stimulus such as chemotherapy. This CSC heterogeneity and dynamism makes them out reach from therapeutic protocols directed to a single target. A further avenue of research in this line will be to uncover mechanisms that trigger this interconversion of cell populations within tumors and target it.展开更多
Using nitrate precursors, a novel spray-drying assisted citrate gel process for the preparation of neodymium-doped yttrium alumi- num garnet （YAG） phase was developed. Synthesis of single-phase polycrystalline YAG w...Using nitrate precursors, a novel spray-drying assisted citrate gel process for the preparation of neodymium-doped yttrium alumi- num garnet （YAG） phase was developed. Synthesis of single-phase polycrystalline YAG was achieved at temperatures as low as 800 ℃ using the spray-drying methodology whilst conventional approaches currently available require 1000 ℃. Initially, a solution was prepared by mixing aluminum and yttrium nitrates, citric acid, etilenglycol and neodymium oxide. This solution was dried by pulverization （spray dryer） to obtain aggregated precursor powders of the compound. These aggregates were calcined at 800, 850 and 900 ℃ to determine the phase evolution from amorphous to crystalline by X-ray diffraction （XRD）. The morphology of aggregates was characterized by scanning electron microscopy （SEM） and transmission electron microscopy （TEM）. Moreover, through XRD it was determined that the crystallization of YAG phase started at about 800 ℃ without any intermediate phases. The powders were composed of spherical aggregates with an average diameter of 1 um. From these powders, ceramic fibers with additions of 2at.% and 5at.% Nd, were extracted from the melt with diameters ranging from 30 um to 50 um.展开更多
AIM： To determine the role of c-Jun N-terminal kinase （JNK） activity in ethanol-induced apoptosis and the modulation of this signaling cascade by S-Adenosylmethionine （AdoMet）. METHODS： Primary hepatocyte cultur...AIM： To determine the role of c-Jun N-terminal kinase （JNK） activity in ethanol-induced apoptosis and the modulation of this signaling cascade by S-Adenosylmethionine （AdoMet）. METHODS： Primary hepatocyte cultures were pretreated with 100 IJmol/L SP600125, a selective JNK inhibitor, 1 mL/L DMSO or 4 mmol/L AdoMet and then exposed to 100 mmo/L ethanol. Hepatocyte apoptosis was determined by the TUNEL and DNA ladder assays. JNK activity and its inhibition by SP600125 and AdoMet were determined by Western blot analysis of c-jun phosphorylation and Bid fragmentation. SP600125 and AdoMet effects on the apoptotic signaling pathway were determined by Western blot analysis of cytochrome c release and pro-caspase 3 fragmentation. The AdoMet effect on glutathione levels was measured by EIIman＇s method and reactive oxygen species （ROS） generation by cell cytometry. RESULTS： The exposure of hepatocytes to ethanol induced JNK activation, c-jun phosphorylation, Bid fragmentation, cytochrome c release and pro-caspase 3 cleavage; these effects were diminished by SP600125, and caused a significant decrease in ethanol-induced apoptosis （P〈 0.05）. AdoMet exerted an antioxidant effect maintaining glutathione levels and decreasing ROS generation, without a significant effect on JNK activity, and prevented cytochrome c release and pro-caspase 3 cleavage.CONCLUSION： The JNK signaling cascade is a key component of the proapoptotic signaling pathway induced by ethanol. JNK activation may be independent from ROS generation, since AdoMet which exerted antioxidant properties did not have a significant effect on JNK activity. JNK pathway modulator agents and AdoMet may be components of promising therapies for alcoholic liver disease （ALD） treatment.展开更多
Two aromatic co-polyamides were synthesized combining two diacid monomers containing bulky pendant groups, 5-(9,10-dihydro-9,10-ethanoanthracene-11,12-dicarboximido)isophthalic acid(DEAIA) and 5-tert-butylisophthalic ...Two aromatic co-polyamides were synthesized combining two diacid monomers containing bulky pendant groups, 5-(9,10-dihydro-9,10-ethanoanthracene-11,12-dicarboximido)isophthalic acid(DEAIA) and 5-tert-butylisophthalic acid(TERT), with 4,4′-(hexafluoroisopropylidene)dianiline(HFA) or 2,3,5,6-tetramethyl-1,4-phenylenediamine(Durene) by direct polycondensation. The structures of the obtained aromatic co-polyamides were confirmed by FTIR, Raman and 1 H-NMR. The co-copolyamide films, DHTH and DDTD, exhibited rms-roughness values between 0.94 and 1.60 nm, respectively. Moreover, they presented good thermal stability up to300 °C. Young's moduli of the co-polyamide films were between 4.1 and 4.3 GPa. X-ray diffraction results showed that the co-polyamide films were amorphous due to the incorporation of both bulky pendant groups, tert-butyl and dibenzobarrelene. The combination of bulky pendant groups provided intrinsically transparent co-polyamide films with a transmittance higher than 88% in the range of 400-780 nm.Due to these outstanding film and optical properties, they are suggested to be flexible substrates in applications for solar cell and other portable electronic devices.展开更多
The anther culture technical was applied to produce haploid lines of rice (Oryza sativa L.). The hybrids (K/ A92VM061, K/A92VM067, K/A92VM0611, K/A92VM719, K/A92VM720 and K/A92VM721) were obtained in order to generate...The anther culture technical was applied to produce haploid lines of rice (Oryza sativa L.). The hybrids (K/ A92VM061, K/A92VM067, K/A92VM0611, K/A92VM719, K/A92VM720 and K/A92VM721) were obtained in order to generate new varieties from Indica and Japonica cultivars. Morphometric parameters of the grains were evaluated by image analysis. Flours were prepared from the whole rice grains and physicochemical, thermal and rheological properties, X-ray diffraction pattern and evaluation of color using the CIELAB system were assessed. The hybrids lines showed long (061, 611, 721), medium (719 and 720) and short (067) grains. The rice samples presented lipids (2.6% - 3.2%), protein (11% - 15%), total dietary fiber (8.4% - 10.2%), total starch (65% - 74%) and apparent amylose (5% - 32%) contents. Gelatinization temperature (Tp) was found in the range of 66.1℃ - 79.4℃ with enthalpy (ΔH) value between 3.4 - 8.1 J/g. The retrogradation parameters (temperature and ΔH) were lower than those for gelatinization in all samples. The rice samples presented A-type X-ray diffraction pattern. Rice pastes showed a non-Newtonian behavior and the brightness (L*) characterize the color of the samples. Hybrid rice grains presented morphometric properties more similar to Japonica than Indica variety. Rice hybrid had higher protein content than Indica variety. Apparent amylose, viscosity and gelatinization temperature varied significantly among hybrids and varieties.展开更多
This article deals with a linear classical approach for the robust output reference trajectory tracking control of nonlinear SISO Lagrangian systems with a controllable(fAat)tangent linearization around an operating e...This article deals with a linear classical approach for the robust output reference trajectory tracking control of nonlinear SISO Lagrangian systems with a controllable(fAat)tangent linearization around an operating equilibrium point.An endogenous injections and exogenous feedback(EIEF)approach is proposed,which is naturally equivalent to the generalized propor-tional integral control method and to a robust classical compensation network.It is shown that the EIEF controller is also equivalent,within a frequency domain setting demanding respect for the separation principle,to the reduced order observer based active disturbance rejection control approach.The proposed linear control approach is robust with respect to total dis-turbances and,thus,it is ffective for the linear control of the nonlinear Lagrangian system.An ilustrative nonlinear rotary crane Lagrangian system example,which is non-feedback linearizable,is presented along with digital computer simulations.展开更多
In this paper, a practical impulsive lag synchronization scheme for different chaotic systems with parametric uncertainties is proposed. By virtue of the new definition of synchronization and the theory of impulsive d...In this paper, a practical impulsive lag synchronization scheme for different chaotic systems with parametric uncertainties is proposed. By virtue of the new definition of synchronization and the theory of impulsive differential equations, some new and less conservative sufficient conditions are established to guarantee that the error dynamics can converge to a predetermined level. The idea and approach developed in this paper can provide a more practical framework for the synchronization between identical and different chaotic systems in parameter perturbation circumstances. Simulation results finally demonstrate the effectiveness of the method.展开更多
In this paper, a Takagi Sugeno （T-S） fuzzy model-based method is proposed to deal with the problem of synchronization of two identical or different hyperchaotic systems. The T S fuzzy models with a small number of f...In this paper, a Takagi Sugeno （T-S） fuzzy model-based method is proposed to deal with the problem of synchronization of two identical or different hyperchaotic systems. The T S fuzzy models with a small number of fuzzy IF-THEN rules are employed to represent many typical hyperchaotic systems exactly. The benefit of employing the T-S fuzzy models lies in mathematical simplicity of analysis. Based on the T-S fuzzy hyperchaotic models, two fuzzy controllers arc designed via parallel distributed compensation （PDC） and exact linearization （EL） techniques to synchronize two identical hyperchaotic systems with uncertain parameters and two different hyperchaotic systems, respectively. The sufficient conditions for the robust synchronization of two identical hyperchaotic systems with uncertain parameters and the asymptotic synchronization of two different hyperchaotic systems are derived by applying the Lyapunov stability theory. This method is a universal one of synchronizing two identical or different hyperchaotic systems. Numerical examples are given to demonstrate the validity of the proposed fuzzy model and hyperchaotic synchronization scheme.展开更多
Erbium and ytterbium doped barium titanate nanopowders were prepared using the hydrothermal method. A barium titanate structure doped with rare earth ions manifested new characteristics and improved the field of appli...Erbium and ytterbium doped barium titanate nanopowders were prepared using the hydrothermal method. A barium titanate structure doped with rare earth ions manifested new characteristics and improved the field of application of optical devices such as trichromatic tubes, LCD displays, lamps, and infrared lasers. In this work, BaTiO3：Er3＋ and BaTiO3：Yb3＋ were prepared using barium chloride [BaCl2], titanium butoxide [C16H36O4Ti], erbium chloride [ErCl3] and ytterbium chloride [YbCl3] as precursors. Anhydrous methanol was employed as a solvent. Metallic potassium was used to promote solubility in the system and increase the pH to 13. This method yielded the formation of a predominantly cubic structure in both Er3＋ and Yb3＋ doped BaTiO3 powders. Characteristic bondings of BaTiO3 were observed with FT-IR spectroscopy. The predominantly cubic structure was confirmed by X-ray diffraction and micro-Raman analyses. The particle size（～30 nm） was estimated using the Scherrer equation and X-ray diffraction data. The results were presented and discussed.展开更多
China’s swift and substantial economic growth over the past 20 years has made the country one of the top industrial powers in the world, second only the United States. From the perspective of ecology and the impact o...China’s swift and substantial economic growth over the past 20 years has made the country one of the top industrial powers in the world, second only the United States. From the perspective of ecology and the impact on the environment produced by economic and industrial growth, the exports that have driven rapid growth have also resulted in an alarming level of environmental pollution in major Chinese cities. Research has shown that the Chinese government’s investment in bringing down pollution levels has been insufficient and ineffective. The monetary amount allocated for pollution reduction has barely reached 0.15% of the country’s GDP and has failed to meaningfully reverse the effects of industrialization, including increased exports and economic growth rates affecting China’s ecology. The present study investigated China’s ecological situation in terms of the industrial production that has generated its level of exports, with special focus on problems related to water, air, and solid waste. An econometric analysis was conducted to determine the relationship between the main variables. The exports and GDP (dependent variable), air pollution, water pollution, and industrial solid waste (independent variables) were provided by the Institute of Statistics and the Environment Institute of China for this study. The data was managed in Econometric Eviews 7.0 software and yielded an adjusted R<sup>2 </sup>of 96.09% (high correlation) with an interesting correlation between the exports and three independent variables;after subsequent variable analysis, we found that investments in water and industrial solid waste were not significant (i.e., that said investments have failed to solve the pollution problem). It is necessary to review the Chinese investment policy with special attention to these variables to appropriately respond to China’s ecological crisis.展开更多
基金partially supported by MICIU MCIN/AEI/10.13039/501100011033Spain with grant PID2020-118265GB-C42,-C44,PRTR-C17.I01+1 种基金Generalitat Valenciana,Spain with grant CIPROM/2022/54,ASFAE/2022/031,CIAPOS/2021/114the EU NextGenerationEU,ESF funds,and the National Science Centre (NCN),Poland (grant No.2020/39/D/ST2/00466)
文摘Pulse pile-up is a problem in nuclear spectroscopy and nuclear reaction studies that occurs when two pulses overlap and distort each other,degrading the quality of energy and timing information.Different methods have been used for pile-up rejection,both digital and analogue,but some pile-up events may contain pulses of interest and need to be reconstructed.The paper proposes a new method for reconstructing pile-up events acquired with a neutron detector array(NEDA)using an one-dimensional convolutional autoencoder(1D-CAE).The datasets for training and testing the 1D-CAE are created from data acquired from the NEDA.The new pile-up signal reconstruction method is evaluated from the point of view of how similar the reconstructed signals are to the original ones.Furthermore,it is analysed considering the result of the neutron-gamma discrimination based on charge comparison,comparing the result obtained from original and reconstructed signals.
基金supported by the Secretaría de Investigación y Posgrado del Instituto Politécnico Nacional(SIP-IPN)under grants 20250098,20250168,20251291 and 20254791by Universidad Iberoamericana Ciudad de México+1 种基金Victor G.Sánchez-Meza is a Secretaría de Ciencia,Humanidades,Tecnología e Innovación(Secihti)fellow(CVU 964590)support received.Yair Lozano thanks the support of the Coordinación de Operación y Redes de Investigación y Posgrado of the IPN through the Red de Inteligencia Artificial y Ciencia de Datos and the Red de Expertos en Innovación Automotriz.
文摘In this article,the dynamical model and trajectory tracking problem for a tilt-rotor unmanned aerial vehicle is tackled through linear Active Disturbance Rejection Control(ADRC)applied on the tangent linearized system.To apply the ADRC scheme,it is considered the subsystem without the Y-axis component,which is differentially flat and whose flat outputs are obtained using the Kronecker matrix.Numerical assessment using as system parameters the ones of a scale prototype is provided to show the effectiveness of the proposal leading to accurate tracking results using admissible control values for an experimental scenario.
文摘In this article, we establish the route taken by the author, and his research group, to bring differential flatness to the realm of active disturbance rejection control （ADRC）. This avenue entitled： 1） generalized proportional integral observers （GPIO）, as natural state and disturbance observers for fiat systems, 2） generalized proportional integral （GPI） control, provided with extra integrations, to produce a modular controller known as flat filters （FF＇s） and, finally, 3） the establishing of an equivalence of observer based ADRC with FF＇s. The context is that of pure integration systems. The obtained controllers depend only on the order of the flat system and they are to be directly used on the basis of the available flat output signal in a universal, modular, fashion. The map is complemented with the relevant references where the intermediate techniques were illustrated and developed, over the years, in connection with laboratory experimental implementations.
基金CONACyT-México for the scholarship providedCONACyT (Project 736)SIP-IPN are also acknowledged for funds given to conduct this research
文摘Heat moving source models along with transient heat analysis by finite element method were used to determine weld thermal cycles and isothermal sections obtained from the application of a gas tungsten arc welding beads on Inconel 718 plates. Analytical (Rosenthal’s thick plate model) and finite element results show an acceptable approximation with the experimental weld thermal cycles. The isothermal sections determined by numerical simulation show a better approximation with the experimental welding profile for double-ellipse model heat distribution than Gauss model. To analyze the microstructural transformation produced by different cooling rates in the fusion and heat affected zones, Vickers microhardness measurements (profile and mapping representation) were conducted. A hardness decrement for the heat affected zone (~200 HV0.2) and fusion zone (~240 HV0.2) in comparison with base material (~350 HV0.2) was observed. This behavior has been attributed to the heterogeneous solubilization process of the γ″ phase (nickel matrix), which, according to the continuous-cooling-transformation curve, produced the Laves phase,δ and MC transition phases, generating a loss in hardness close to the fusion zone.
文摘Carcinogenic process has been proposed to relay on the capacity to induce local tissue damage and proliferative repair. Liver has a great regeneration capacity and currently, most studies point towards the dominant role of hepatocytes in regeneration at all levels of liver damage. The most frequent liver cancer is hepatocellular carcinoma(HCC). Historical findings originally led to the idea that the cell of origin of HCC might be a progenitor cell. However, current linage tracing studies put the progenitor hypothesis of HCC origin into question. In agreement with their dominant role in liver regeneration, mature hepatocytes are emerging as the cell of origin of HCC, although, the specific hepatocyte subpopulation of origin is yet to be determined. The relationship between the cancer cell of origin(CCO) and cancer-propagating cells, known as hepatic cancer stem cell(HCSC) is unknown. It has been challenging to identify the definitive phenotypic marker of HCSC, probably due to the existence of different cancer stem cells(CSC) subpopulations with different functions within HCC. There is a dynamic interconversion among different CSCs, and between CSC and non-CSCs. Because of that, CSC-state is currently defined as a description of a highly adaptable and dynamic intrinsic property of tumor cells, instead of a static subpopulation of a tumor. Altered conditions could trigger the gain of stemness, some of them include: EMT-MET, epigenetics, microenvironment and selective stimulus such as chemotherapy. This CSC heterogeneity and dynamism makes them out reach from therapeutic protocols directed to a single target. A further avenue of research in this line will be to uncover mechanisms that trigger this interconversion of cell populations within tumors and target it.
基金Universidad Michoacana de San Nicolás de Hidalgo (UMSNH) (1.24.-2005-2007)
文摘Using nitrate precursors, a novel spray-drying assisted citrate gel process for the preparation of neodymium-doped yttrium alumi- num garnet （YAG） phase was developed. Synthesis of single-phase polycrystalline YAG was achieved at temperatures as low as 800 ℃ using the spray-drying methodology whilst conventional approaches currently available require 1000 ℃. Initially, a solution was prepared by mixing aluminum and yttrium nitrates, citric acid, etilenglycol and neodymium oxide. This solution was dried by pulverization （spray dryer） to obtain aggregated precursor powders of the compound. These aggregates were calcined at 800, 850 and 900 ℃ to determine the phase evolution from amorphous to crystalline by X-ray diffraction （XRD）. The morphology of aggregates was characterized by scanning electron microscopy （SEM） and transmission electron microscopy （TEM）. Moreover, through XRD it was determined that the crystallization of YAG phase started at about 800 ℃ without any intermediate phases. The powders were composed of spherical aggregates with an average diameter of 1 um. From these powders, ceramic fibers with additions of 2at.% and 5at.% Nd, were extracted from the melt with diameters ranging from 30 um to 50 um.
文摘AIM： To determine the role of c-Jun N-terminal kinase （JNK） activity in ethanol-induced apoptosis and the modulation of this signaling cascade by S-Adenosylmethionine （AdoMet）. METHODS： Primary hepatocyte cultures were pretreated with 100 IJmol/L SP600125, a selective JNK inhibitor, 1 mL/L DMSO or 4 mmol/L AdoMet and then exposed to 100 mmo/L ethanol. Hepatocyte apoptosis was determined by the TUNEL and DNA ladder assays. JNK activity and its inhibition by SP600125 and AdoMet were determined by Western blot analysis of c-jun phosphorylation and Bid fragmentation. SP600125 and AdoMet effects on the apoptotic signaling pathway were determined by Western blot analysis of cytochrome c release and pro-caspase 3 fragmentation. The AdoMet effect on glutathione levels was measured by EIIman＇s method and reactive oxygen species （ROS） generation by cell cytometry. RESULTS： The exposure of hepatocytes to ethanol induced JNK activation, c-jun phosphorylation, Bid fragmentation, cytochrome c release and pro-caspase 3 cleavage; these effects were diminished by SP600125, and caused a significant decrease in ethanol-induced apoptosis （P〈 0.05）. AdoMet exerted an antioxidant effect maintaining glutathione levels and decreasing ROS generation, without a significant effect on JNK activity, and prevented cytochrome c release and pro-caspase 3 cleavage.CONCLUSION： The JNK signaling cascade is a key component of the proapoptotic signaling pathway induced by ethanol. JNK activation may be independent from ROS generation, since AdoMet which exerted antioxidant properties did not have a significant effect on JNK activity. JNK pathway modulator agents and AdoMet may be components of promising therapies for alcoholic liver disease （ALD） treatment.
基金the financial support from CONACYT-México(No.248378)CONACYT-México for the fellowship 427467partially supported by the project "Fortalecimiento e internacionalización del doctorado en ciencias(Materiales Poliméricos)del CICY" FOMIX YUC 2014-C17-247046
文摘Two aromatic co-polyamides were synthesized combining two diacid monomers containing bulky pendant groups, 5-(9,10-dihydro-9,10-ethanoanthracene-11,12-dicarboximido)isophthalic acid(DEAIA) and 5-tert-butylisophthalic acid(TERT), with 4,4′-(hexafluoroisopropylidene)dianiline(HFA) or 2,3,5,6-tetramethyl-1,4-phenylenediamine(Durene) by direct polycondensation. The structures of the obtained aromatic co-polyamides were confirmed by FTIR, Raman and 1 H-NMR. The co-copolyamide films, DHTH and DDTD, exhibited rms-roughness values between 0.94 and 1.60 nm, respectively. Moreover, they presented good thermal stability up to300 °C. Young's moduli of the co-polyamide films were between 4.1 and 4.3 GPa. X-ray diffraction results showed that the co-polyamide films were amorphous due to the incorporation of both bulky pendant groups, tert-butyl and dibenzobarrelene. The combination of bulky pendant groups provided intrinsically transparent co-polyamide films with a transmittance higher than 88% in the range of 400-780 nm.Due to these outstanding film and optical properties, they are suggested to be flexible substrates in applications for solar cell and other portable electronic devices.
文摘The anther culture technical was applied to produce haploid lines of rice (Oryza sativa L.). The hybrids (K/ A92VM061, K/A92VM067, K/A92VM0611, K/A92VM719, K/A92VM720 and K/A92VM721) were obtained in order to generate new varieties from Indica and Japonica cultivars. Morphometric parameters of the grains were evaluated by image analysis. Flours were prepared from the whole rice grains and physicochemical, thermal and rheological properties, X-ray diffraction pattern and evaluation of color using the CIELAB system were assessed. The hybrids lines showed long (061, 611, 721), medium (719 and 720) and short (067) grains. The rice samples presented lipids (2.6% - 3.2%), protein (11% - 15%), total dietary fiber (8.4% - 10.2%), total starch (65% - 74%) and apparent amylose (5% - 32%) contents. Gelatinization temperature (Tp) was found in the range of 66.1℃ - 79.4℃ with enthalpy (ΔH) value between 3.4 - 8.1 J/g. The retrogradation parameters (temperature and ΔH) were lower than those for gelatinization in all samples. The rice samples presented A-type X-ray diffraction pattern. Rice pastes showed a non-Newtonian behavior and the brightness (L*) characterize the color of the samples. Hybrid rice grains presented morphometric properties more similar to Japonica than Indica variety. Rice hybrid had higher protein content than Indica variety. Apparent amylose, viscosity and gelatinization temperature varied significantly among hybrids and varieties.
基金The work of M.A.Aguilar-Orduia and B.C.Gomez-Leon was supported by Consejo Nacional de Ciencia y Tec-nologia(CONACYT)Mexico under Scholarship Grants no.702805 and no.1039577,respectively.
文摘This article deals with a linear classical approach for the robust output reference trajectory tracking control of nonlinear SISO Lagrangian systems with a controllable(fAat)tangent linearization around an operating equilibrium point.An endogenous injections and exogenous feedback(EIEF)approach is proposed,which is naturally equivalent to the generalized propor-tional integral control method and to a robust classical compensation network.It is shown that the EIEF controller is also equivalent,within a frequency domain setting demanding respect for the separation principle,to the reduced order observer based active disturbance rejection control approach.The proposed linear control approach is robust with respect to total dis-turbances and,thus,it is ffective for the linear control of the nonlinear Lagrangian system.An ilustrative nonlinear rotary crane Lagrangian system example,which is non-feedback linearizable,is presented along with digital computer simulations.
基金Project supported by the National Natural Science foundation of China (Grant Nos 60534010, 60572070, 60774048 and 60728307)the Program for Changjiang Scholars and Innovative Research Team in University (Grant No 60521003) the National High Technology Research and Development Program of China (Grant No 2006AA04Z183)
文摘In this paper, a practical impulsive lag synchronization scheme for different chaotic systems with parametric uncertainties is proposed. By virtue of the new definition of synchronization and the theory of impulsive differential equations, some new and less conservative sufficient conditions are established to guarantee that the error dynamics can converge to a predetermined level. The idea and approach developed in this paper can provide a more practical framework for the synchronization between identical and different chaotic systems in parameter perturbation circumstances. Simulation results finally demonstrate the effectiveness of the method.
基金Project supported by the National Natural Science Foundation of China (Grant Nos 60534010, 60572070, 60774048 and 60728307)the Program for Changjiang Scholars and Innovative Research Groups of China (Grant No 60521003)+1 种基金the Specialized Research Fund for the Doctoral Program of Higher Education of China (Grant No 20070145015)the National High Technology Research and Development Program of China (Grant No 2006AA04Z183)
文摘In this paper, a Takagi Sugeno （T-S） fuzzy model-based method is proposed to deal with the problem of synchronization of two identical or different hyperchaotic systems. The T S fuzzy models with a small number of fuzzy IF-THEN rules are employed to represent many typical hyperchaotic systems exactly. The benefit of employing the T-S fuzzy models lies in mathematical simplicity of analysis. Based on the T-S fuzzy hyperchaotic models, two fuzzy controllers arc designed via parallel distributed compensation （PDC） and exact linearization （EL） techniques to synchronize two identical hyperchaotic systems with uncertain parameters and two different hyperchaotic systems, respectively. The sufficient conditions for the robust synchronization of two identical hyperchaotic systems with uncertain parameters and the asymptotic synchronization of two different hyperchaotic systems are derived by applying the Lyapunov stability theory. This method is a universal one of synchronizing two identical or different hyperchaotic systems. Numerical examples are given to demonstrate the validity of the proposed fuzzy model and hyperchaotic synchronization scheme.
基金Project supported by CONACYT Through Project 100764the IPN Through Projects SIP-2013664,SIP-2013665SEP-CONACYT ANUIES PROJECT M09P01
文摘Erbium and ytterbium doped barium titanate nanopowders were prepared using the hydrothermal method. A barium titanate structure doped with rare earth ions manifested new characteristics and improved the field of application of optical devices such as trichromatic tubes, LCD displays, lamps, and infrared lasers. In this work, BaTiO3：Er3＋ and BaTiO3：Yb3＋ were prepared using barium chloride [BaCl2], titanium butoxide [C16H36O4Ti], erbium chloride [ErCl3] and ytterbium chloride [YbCl3] as precursors. Anhydrous methanol was employed as a solvent. Metallic potassium was used to promote solubility in the system and increase the pH to 13. This method yielded the formation of a predominantly cubic structure in both Er3＋ and Yb3＋ doped BaTiO3 powders. Characteristic bondings of BaTiO3 were observed with FT-IR spectroscopy. The predominantly cubic structure was confirmed by X-ray diffraction and micro-Raman analyses. The particle size（～30 nm） was estimated using the Scherrer equation and X-ray diffraction data. The results were presented and discussed.
文摘China’s swift and substantial economic growth over the past 20 years has made the country one of the top industrial powers in the world, second only the United States. From the perspective of ecology and the impact on the environment produced by economic and industrial growth, the exports that have driven rapid growth have also resulted in an alarming level of environmental pollution in major Chinese cities. Research has shown that the Chinese government’s investment in bringing down pollution levels has been insufficient and ineffective. The monetary amount allocated for pollution reduction has barely reached 0.15% of the country’s GDP and has failed to meaningfully reverse the effects of industrialization, including increased exports and economic growth rates affecting China’s ecology. The present study investigated China’s ecological situation in terms of the industrial production that has generated its level of exports, with special focus on problems related to water, air, and solid waste. An econometric analysis was conducted to determine the relationship between the main variables. The exports and GDP (dependent variable), air pollution, water pollution, and industrial solid waste (independent variables) were provided by the Institute of Statistics and the Environment Institute of China for this study. The data was managed in Econometric Eviews 7.0 software and yielded an adjusted R<sup>2 </sup>of 96.09% (high correlation) with an interesting correlation between the exports and three independent variables;after subsequent variable analysis, we found that investments in water and industrial solid waste were not significant (i.e., that said investments have failed to solve the pollution problem). It is necessary to review the Chinese investment policy with special attention to these variables to appropriately respond to China’s ecological crisis.
