Peripartum cardiomyopathy(PPCM) represents new heart failure in a previously heart-healthy peripartum patient. It is necessary to rule out all other known causes of heart failure before accepting a diagnosis of PPCM. ...Peripartum cardiomyopathy(PPCM) represents new heart failure in a previously heart-healthy peripartum patient. It is necessary to rule out all other known causes of heart failure before accepting a diagnosis of PPCM. The modern era for PPCM in the United States and beyond began with the report of the National In-stitutes of Health PPCM Workshop in 2000, clarifying all then-currently known aspects of the disease. Since then, hundreds of publications have appeared, an indi-cation of how devastating this disease can be to young mothers and their families and the urgent desire to find solutions for its cause and better treatment. The purpose of this review is to highlight the important ad-vances that have brought us nearer to the solution of this puzzle, focusing on what we have learned about PPCM since 2000; and what still remains unanswered. Despite many improvements in outcome, we still do not know the actual triggers that initiate the pathological process; but realize that cardiac angiogenic imbalances resulting from complex pregnancy-related immune sys-tem and hormonal changes play a key role.展开更多
We constrain the host-star flux of the microlensing planet OGLE-2014-BLG-0676 Lb using adaptive optics(AO)images taken by the Magellan and Keck telescopes.We measure the flux of the light blended with the microlensed ...We constrain the host-star flux of the microlensing planet OGLE-2014-BLG-0676 Lb using adaptive optics(AO)images taken by the Magellan and Keck telescopes.We measure the flux of the light blended with the microlensed source to be K=16.79±0.04 mag and J=17.76±0.03 mag.Assuming that the blend is the lens star,we find that the host is a 0.73_(-0.29)^(+0.14)M_(⊙)star at a distance of2.67_(-1.41)^(+0.77)kpc,where the relatively large uncertainty in angular Einstein radius measurement is the major source of uncertainty.With mass of M_(p)=3.68_(-1.44)^(+0.69)M_J,the planet is likely a"super Jupiter"at a projected separation of r_(⊥)=4.53_(-2.50)^(+1.49)AU,and a degenerate model yields a similar M_p=3.73_(-1.47)^(+0.73)M_(J)at a closer separation of r_(⊥)=2.56_(-1.41)^(+0.84)AU.Our estimates are consistent with the previous Bayesian analysis based on a Galactic model.OGLE-2014-BLG-0676 Lb belongs to a sample of planets discovered in a"secondgeneration"planetary microlensing survey and we attempt to systematically constrain host properties of this sample with high-resolution imaging to study the distribution of planets.展开更多
We report the confirmation of a sub-Saturn-size exoplanet,TOI-1194 b,with a mass of about 0.456+0.055-0.051M_(J),and a very low mass companion star with a mass of about 96.5±1.5 MJ,TOI-1251 B.Exoplanet candidates...We report the confirmation of a sub-Saturn-size exoplanet,TOI-1194 b,with a mass of about 0.456+0.055-0.051M_(J),and a very low mass companion star with a mass of about 96.5±1.5 MJ,TOI-1251 B.Exoplanet candidates provided by the Transiting Exoplanet Survey Satellite(TESS)are suitable for further follow-up observations by ground-based telescopes with small and medium apertures.The analysis is performed based on data from several telescopes worldwide,including telescopes in the Sino-German multiband photometric campaign,which aimed at confirming TESS Objects of Interest(TOIs)using ground-based small-aperture and medium-aperture telescopes,especially for long-period targets.TOI-1194 b is confirmed based on the consistent periodic transit depths from the multiband photometric data.We measure an orbital period of 2.310644±0.000001 days,the radius is 0.767+0.045-0.041RJ and the amplitude of the RV curve is 69.4_(-7.3)^(+7.9)m s^(-1).TOI-1251 B is confirmed based on the multiband photometric and high-resolution spectroscopic data,whose orbital period is 5.963054+0.000002-0.000001days,radius is 0.947+0.035-0.033 R_(J) and amplitude of the RV curve is 9849_(-40)^(+42)ms^(-1).展开更多
文摘Peripartum cardiomyopathy(PPCM) represents new heart failure in a previously heart-healthy peripartum patient. It is necessary to rule out all other known causes of heart failure before accepting a diagnosis of PPCM. The modern era for PPCM in the United States and beyond began with the report of the National In-stitutes of Health PPCM Workshop in 2000, clarifying all then-currently known aspects of the disease. Since then, hundreds of publications have appeared, an indi-cation of how devastating this disease can be to young mothers and their families and the urgent desire to find solutions for its cause and better treatment. The purpose of this review is to highlight the important ad-vances that have brought us nearer to the solution of this puzzle, focusing on what we have learned about PPCM since 2000; and what still remains unanswered. Despite many improvements in outcome, we still do not know the actual triggers that initiate the pathological process; but realize that cardiac angiogenic imbalances resulting from complex pregnancy-related immune sys-tem and hormonal changes play a key role.
基金the support by National Key R&D Program of China(No.2019YFA0405100)the China Manned Space Project with NO.CMS-CSST-2021-A11 and+6 种基金Project 11573003 supported by the National Natural Science Foundation of China(NSFC)supported by a NASA Keck PI Data Awardpossible by the generous financial support of the W.M.Keck Foundationfunding from the National Science Centre,Poland,grant MAESTRO 2014/14/A/ST9/00121 to AUthe financial support of the ANR COLD WORLDS(ANR-18-CE31-0002)supported by the NASA Exoplanets Research Program(XRP)by cooperative agreement NNX16AD44Gsupported by the University of Tasmania through the UTAS Foundation and the endowed Warren Chair in Astronomy。
文摘We constrain the host-star flux of the microlensing planet OGLE-2014-BLG-0676 Lb using adaptive optics(AO)images taken by the Magellan and Keck telescopes.We measure the flux of the light blended with the microlensed source to be K=16.79±0.04 mag and J=17.76±0.03 mag.Assuming that the blend is the lens star,we find that the host is a 0.73_(-0.29)^(+0.14)M_(⊙)star at a distance of2.67_(-1.41)^(+0.77)kpc,where the relatively large uncertainty in angular Einstein radius measurement is the major source of uncertainty.With mass of M_(p)=3.68_(-1.44)^(+0.69)M_J,the planet is likely a"super Jupiter"at a projected separation of r_(⊥)=4.53_(-2.50)^(+1.49)AU,and a degenerate model yields a similar M_p=3.73_(-1.47)^(+0.73)M_(J)at a closer separation of r_(⊥)=2.56_(-1.41)^(+0.84)AU.Our estimates are consistent with the previous Bayesian analysis based on a Galactic model.OGLE-2014-BLG-0676 Lb belongs to a sample of planets discovered in a"secondgeneration"planetary microlensing survey and we attempt to systematically constrain host properties of this sample with high-resolution imaging to study the distribution of planets.
基金supported by National Natural Science Foundation of China(NSFC,Grant Nos.U1831209 and U2031144)the research fund of Ankara University(BAP)through the project 18A0759001。
文摘We report the confirmation of a sub-Saturn-size exoplanet,TOI-1194 b,with a mass of about 0.456+0.055-0.051M_(J),and a very low mass companion star with a mass of about 96.5±1.5 MJ,TOI-1251 B.Exoplanet candidates provided by the Transiting Exoplanet Survey Satellite(TESS)are suitable for further follow-up observations by ground-based telescopes with small and medium apertures.The analysis is performed based on data from several telescopes worldwide,including telescopes in the Sino-German multiband photometric campaign,which aimed at confirming TESS Objects of Interest(TOIs)using ground-based small-aperture and medium-aperture telescopes,especially for long-period targets.TOI-1194 b is confirmed based on the consistent periodic transit depths from the multiband photometric data.We measure an orbital period of 2.310644±0.000001 days,the radius is 0.767+0.045-0.041RJ and the amplitude of the RV curve is 69.4_(-7.3)^(+7.9)m s^(-1).TOI-1251 B is confirmed based on the multiband photometric and high-resolution spectroscopic data,whose orbital period is 5.963054+0.000002-0.000001days,radius is 0.947+0.035-0.033 R_(J) and amplitude of the RV curve is 9849_(-40)^(+42)ms^(-1).
