Spinal cord injury(SCI)can cause motor and sensory paralysis,and autonomic nervous system disorders including malfunction of urination and defecation,thereby significantly impairing the quality of life.Researchers con...Spinal cord injury(SCI)can cause motor and sensory paralysis,and autonomic nervous system disorders including malfunction of urination and defecation,thereby significantly impairing the quality of life.Researchers continue to explo re new stem cell strategies for the treatment of paralysis by transpla nting human induced pluripotent stem cell-derived neural ste m/progenitor cells(hiPSCNS/PCs)into spinal cord injured tissues.展开更多
The integration of dual-mesoporous structures,the construction of heterojunctions,and the incorporation of highly concentrated oxygen vacancies are pivotal for advancing metal oxide-based gas sensors.Nonetheless,achie...The integration of dual-mesoporous structures,the construction of heterojunctions,and the incorporation of highly concentrated oxygen vacancies are pivotal for advancing metal oxide-based gas sensors.Nonetheless,achieving an optimal design that simultaneously combines mesoporous structures,precise heterojunction modulation,and controlled oxygen vacancies through a one-step process remains challenging.This study proposes an innovative method for fabricating zinc stannate semiconductors featuring dual-mesoporous structures and tunable oxygen vacancies via a direct solution precursor plasma spray technique.As a proof of concept,the resulting zinc stannate-based coatings are applied to detect 2-undecanone,a key biomarker for rice aging.Remarkably,the zinc oxide/zinc stannate heterojunctions with a well-defined secondary pore structure exhibit exceptional gas-sensing performance for 2-undecanone at room temperature.Furthermore,practical experiments indicate that the developed sensor effectively identifies adulteration in various rice varieties.These results underscore the potential of this method for designing metal oxides with tailored properties for high-performance gas sensors.The enhanced adsorption capacity and dual-mesoporous features of this semiconductor make it a promising candidate for sensing applications in agricultural food safety inspections.展开更多
Intermetallic alloys offer exceptional high-temperature mechanical properties and low densities,thus rendering them suitable for a wide range of applications in aviation and spacecraft.However,their inherent brittlene...Intermetallic alloys offer exceptional high-temperature mechanical properties and low densities,thus rendering them suitable for a wide range of applications in aviation and spacecraft.However,their inherent brittleness at room temperature poses challenges in the manufacture of complex geometries.Hence,Laser additive manufacturing(LAM)has emerged as a promising approach to investigate the potential limitations of these materials.This review discusses the key findings and challenges associated with the LAM of intermetallic alloys,particu-larly NiAl,Ni_(3)Al,and TiAl,whose engineering applications are substantial.It provides an overview of typical defect morphologies,formation mechanisms,and strategies to prevent cracks and pores.Additionally,it presents an analysis of the microstructural characteristics of as-built and post-treated samples compared with those of samples prepared conventionally.Furthermore,the mechanical properties of the above-mentioned alloys at both room and high temperatures are reviewed,thus highlighting the effects of post-treatment processes.This review concludes with summary tables detailing the mechanical properties,which serve as useful references for researchers.展开更多
The inner Milky Way disk globular cluster NGC 6362 appears to exhibit tidal tails composed of stars that have proper motions and positions in the color–magnitude diagram similar to those of cluster stars. Because rec...The inner Milky Way disk globular cluster NGC 6362 appears to exhibit tidal tails composed of stars that have proper motions and positions in the color–magnitude diagram similar to those of cluster stars. Because recent results seem also to show that these stars are distributed across the regions least affected by interstellar absorption and reproduce the observed composite star field density map, we carried out a detailed spectroscopic analysis of a number of chemical element abundances of tidal tail star candidates in order to investigate the relationship between them and NGC 6362. From European Southern Observatory's VLT@FLAMES spectra we found that the red giant branch stars selected as the cluster's tidal tail stars neither have overall metallicities nor abundances of Mg, Ca, Sc, Ti, Cr, Ni and Ba similar to the cluster's ones. Moreover, they are mainly alike to stars that belong to the Milky Way thick disk, some of them could be part of the thin disk and a minor percentage could belong to the Milky Way halo star population. On the other hand, since the resulting radial velocities do not exhibit a distribution function similar to that of the cluster's stars, we concluded that looking for kinematic properties similar to those of the cluster would not seem to be as suitable of an approach for selecting the cluster's tidal tail stars as previously thought.展开更多
It was in the 1980s that research on somatostatin(SST)in Alzheimer’s disease(AD)truly gained traction,demonstrating consistent colocalization with amyloid-β(Aβ),along with massive SST/SST cell losses(Almeida,2024)....It was in the 1980s that research on somatostatin(SST)in Alzheimer’s disease(AD)truly gained traction,demonstrating consistent colocalization with amyloid-β(Aβ),along with massive SST/SST cell losses(Almeida,2024).Although the field already had some grasp over the neuroendocrine and hypothalamic functions of the peptide,very little was known about the GABAergic interneurons(SST-INs)that synthesize it in cortical/hippocampal regions.Quite excitingly,over 40 years later,research has grown effervescent.展开更多
Objective:To investigate mutations in the Chikungunya(CHIKV)envelope genome region and evaluate their potential impact on B lymphocyte epitopes via in silico analysis.Methods:E1,E2 and 6K protein genes were sequenced ...Objective:To investigate mutations in the Chikungunya(CHIKV)envelope genome region and evaluate their potential impact on B lymphocyte epitopes via in silico analysis.Methods:E1,E2 and 6K protein genes were sequenced from viral RNA isolated from 13 CHIKV-positive serum samples from Alagoas State,Brazil,during the 2016 outbreak.Phylogenetic analysis,experimental epitope identification in the immune epitope database(IEDB)and in silico approaches were employed to predict the potential impact of the detected mutations.Results:The sequences were clustered via phylogenetic analysis.The CHIKV isolates belong to the ECSA genotype,with 13 detected amino acid mutations.Five mutations are located on the surface of the viral particle in regions critical for cellular receptor interaction.Nine mutations are known experimentally validated epitopes for B and T cells.In B-cell epitope predictions,mutations affect sequences within three conformational epitopes in E2 and one in E1,as well as linear epitopes.Notably,the E2-G60D mutation found in the Alagoas strain has been previously reported to influence the vector competence of Aedes aegypti,the primary vector in Brazil.Conclusions:Genomic surveillance and an in-depth understanding of viral mutations are crucial for adapting public health strategies and improving the outbreak response.These findings could have significant public health implications,such as the development of more effective vaccines,diagnostic tests,and antiviral therapies.展开更多
Land use change and occupation have led to modifications in the environment causing loss of biodiversity and ecosystem services throughout the planet.Some environments with high economic relevance,such as the ferrugin...Land use change and occupation have led to modifications in the environment causing loss of biodiversity and ecosystem services throughout the planet.Some environments with high economic relevance,such as the ferruginous campo rupestre(rupestrian grassland known as Canga in Brazil),are even more susceptible to severe impacts due to their extreme habitat conditions and low resilience.The determination of reference ecosystems based on the intrinsic characteristics of the ecosystem is essential for conservation as well as to the implementation of ecological restoration.We proposed the reference ecosystem of the three main types of habitats of the ferruginous campo rupestre based on their floristic composition.We described the floristic composition of each habitat and evaluated the physicochemical properties of the soils and the relationship between plants and soils.All three habitats showed high diversity of plant species and many endemic species,such as Chamaecrista choriophylla,Cuphea pseudovaccinium,Lychnophora pinaster,and Vellozia subalata.The distribution of vegetation was strongly related with the edaphic characteristics,with a set of species more adapted to high concentration of base saturation,fine sand,organic carbon,and iron,while another set of species succeeded in more acidic soils with higher S and silt concentration.We provide support for the contention that the ferruginous campo rupestre is a mosaic of different habitats shaped by intrinsic local conditions.Failure to recognize the floristic composition of each particular habitat can lead to inappropriate restoration,increased habitat homogenization and increased loss of biodiversity and ecosystem services.This study also advances the knowledge base for building the reference ecosystem for the different types of ferruginous campo rupestre habitats,as well as a key database for highlighting those species contribute most to community assembly in this diverse and threatened tropical mountain ecosystem.展开更多
针对智能交通领域多车协同驾驶中存在的通信信息乱序、丢包问题,研究网联式自主驾驶车辆协同控制技术,建立基于零阶保持(Zero Order Hold,ZOH)信息处理机制的自主驾驶车队控制模型,通过非线性系统状态估计算法进行延迟补偿,使得车队控...针对智能交通领域多车协同驾驶中存在的通信信息乱序、丢包问题,研究网联式自主驾驶车辆协同控制技术,建立基于零阶保持(Zero Order Hold,ZOH)信息处理机制的自主驾驶车队控制模型,通过非线性系统状态估计算法进行延迟补偿,使得车队控制模型在复杂汽车行驶环境下保持有效。通过构建由多辆实车组成的网联式自主驾驶车队,在封闭道路环境下进行协同驾驶编队测试,结合网络传输及传感器数据进行模型仿真,验证了模型在实车编队环境下的稳定性、有效性和实用性。展开更多
This work focused on the deposition characteristics and wear behavior of Ni-coated graphite mixed with40 vol.% Al（Ni-Gr/Al） composite coatings sprayed on an Al alloy and a steel substrate by cold spraying（CS）. The...This work focused on the deposition characteristics and wear behavior of Ni-coated graphite mixed with40 vol.% Al（Ni-Gr/Al） composite coatings sprayed on an Al alloy and a steel substrate by cold spraying（CS）. The morphology of the flattened Ni-Gr particles was examined by single-impact tests. Crosssectional microstructure and wear performance of the Ni-Gr/Al composite coatings were studied. Results showed that a larger number of Ni-Gr particles were finally bonded with the steel substrate, whereas many craters existed on the Al alloy substrate after the single-impact tests. The coating on the steel substrate had a high thickness, high graphite content and low coeficient of friction（COF） compared to those on the Al alloy substrate. In addition, the CS coatings presented a homogeneous distribution and uniform morphology of graphite, and a comparative COF to that of conventional thermal sprayed coatings. It was shown that CS could avoid the decomposition and transformation of graphite phase.展开更多
This work concerns the structural evolution of Cu70Nb20Al10(at%) alloy processed by mechanical alloying using a planetary ball mill in air atmosphere for different times(4 to 200 h). The morphological, structural, mic...This work concerns the structural evolution of Cu70Nb20Al10(at%) alloy processed by mechanical alloying using a planetary ball mill in air atmosphere for different times(4 to 200 h). The morphological, structural, microstructural, and thermal behaviors of the alloy were investigated by scanning electron microscopy, energy-dispersive spectroscopy, X-ray diffraction, and differential scanning calorimetry. X-ray diffraction patterns were examined using the Rietveld refinement technique with the help of the MAUD software. A disordered FCC-Cu(Nb,Al) solid solution was formed after 8 h of milling. The crystallite size, microstrain, and lattice parameter were determined by the Rietveld method. With increasing milling time, the crystallite size of the final product-ternary-phase FCC-Cu(Nb,Al)-is refined to the nanometer scale, reaching 12 nm after 200 h. This crystallographic structure combines good mechanical strength and good ductility. An increase in microstrain and partial oxidation were also observed with increasing milling time.展开更多
The excessive concentration of NO_(2) in the atmosphere has gained considerable attention due to its damage to the environment and human health. Gas sensor technology has important application prospects in detecting a...The excessive concentration of NO_(2) in the atmosphere has gained considerable attention due to its damage to the environment and human health. Gas sensor technology has important application prospects in detecting atmospheric NO_(2) concentration. Restricted by its wide bandgap, pristine ZnO needs additional energy to power the electronic transition as a gas sensing material.展开更多
Function of lactate:Lactate is a three-carbon molecule produced by glycolytic metabolism that is a metabolic waste product with no known use in clinical therapy.Conversely,it is a metabolite that the body should quick...Function of lactate:Lactate is a three-carbon molecule produced by glycolytic metabolism that is a metabolic waste product with no known use in clinical therapy.Conversely,it is a metabolite that the body should quickly guarantee the clearance.However,lactate is now recognized as a potential energy substrate,as well as an anti-inflammatory signaling molecule.These actions were first reported in adult animal models with a brain injury,including a traumatic brain injury and cerebral ischemia,and have also been observed in human patients(Magistretti and Allaman,2018).Recently,however,two studies by independent research groups described promising n euro p rotective results from the use of lactate in animal models with neonatal hypoxia-ischemia(Roumes et al.,2021;Tassinari et al.,2020).展开更多
The. objectives.of this study are to convert at laboratory s.cale agric.ultural residues into activated carbons （AC） with specific properties, to characterize them and to test them in adsorption reactor for tetracyc...The. objectives.of this study are to convert at laboratory s.cale agric.ultural residues into activated carbons （AC） with specific properties, to characterize them and to test them in adsorption reactor for tetracycline removal, a common antibiotic. Two new ACs were produced by direct activation with steam from beet pulp （BP-H2O） and peanut hu_lls （PH-H2O） in environmental friendly conditions BP-H2O and PH-H2Opresentcarbon content rangedcarbons with different intrinsic properties.展开更多
A fully dense carbon nanotubes (CNTs) reinforced AlSi matrix composite with the multiscale nacre-like architecture was designed and successfully realized by flake powder metallurgy followed by cold spraying (CS). The ...A fully dense carbon nanotubes (CNTs) reinforced AlSi matrix composite with the multiscale nacre-like architecture was designed and successfully realized by flake powder metallurgy followed by cold spraying (CS). The nanolaminated and ultrafine-grained structure initially created in the CNT/AlSi flaky powder was perfectly conserved, due to the typical ‘cold’ feature of CS. As discussed based on finite element analysis and single splat observation, self-alignment behavior of the flaky powders during impact also allowed the formation of the microlaminated structure. Hence, the scalable CS technique opens a new avenue for bioinspired material design and fabrication with complex shape.展开更多
基金supported by the Keio University Medical Science Fund(to YO)the General Insurance Association of Japan(to YK)+1 种基金the Takeda Science Foundation(to YK)grants from the Japan Agency for Medical Research and Development(AMED)(Grant JP24bm1123037 and JP24ym0126118)(to HO)。
文摘Spinal cord injury(SCI)can cause motor and sensory paralysis,and autonomic nervous system disorders including malfunction of urination and defecation,thereby significantly impairing the quality of life.Researchers continue to explo re new stem cell strategies for the treatment of paralysis by transpla nting human induced pluripotent stem cell-derived neural ste m/progenitor cells(hiPSCNS/PCs)into spinal cord injured tissues.
基金supported by the Outstanding Youth Foundation of Jiangsu Province of China(Grant No.BK20211548)the Yangzhou Science and Technology Plan Project(Grant No.YZ2023246)。
文摘The integration of dual-mesoporous structures,the construction of heterojunctions,and the incorporation of highly concentrated oxygen vacancies are pivotal for advancing metal oxide-based gas sensors.Nonetheless,achieving an optimal design that simultaneously combines mesoporous structures,precise heterojunction modulation,and controlled oxygen vacancies through a one-step process remains challenging.This study proposes an innovative method for fabricating zinc stannate semiconductors featuring dual-mesoporous structures and tunable oxygen vacancies via a direct solution precursor plasma spray technique.As a proof of concept,the resulting zinc stannate-based coatings are applied to detect 2-undecanone,a key biomarker for rice aging.Remarkably,the zinc oxide/zinc stannate heterojunctions with a well-defined secondary pore structure exhibit exceptional gas-sensing performance for 2-undecanone at room temperature.Furthermore,practical experiments indicate that the developed sensor effectively identifies adulteration in various rice varieties.These results underscore the potential of this method for designing metal oxides with tailored properties for high-performance gas sensors.The enhanced adsorption capacity and dual-mesoporous features of this semiconductor make it a promising candidate for sensing applications in agricultural food safety inspections.
基金supported by National Key Research and Development Program of China(Grant No.2021YFB3702502)National Natural Science Foundation of China(Grant Nos.52271035,and 52474412)+1 种基金Natural Science Foundation of Shanghai,China(Grant No.23ZR1421500)the SPMI Project from Shanghai Academy of Spaceflight Technology(Grant No.SPMI2022-06).
文摘Intermetallic alloys offer exceptional high-temperature mechanical properties and low densities,thus rendering them suitable for a wide range of applications in aviation and spacecraft.However,their inherent brittleness at room temperature poses challenges in the manufacture of complex geometries.Hence,Laser additive manufacturing(LAM)has emerged as a promising approach to investigate the potential limitations of these materials.This review discusses the key findings and challenges associated with the LAM of intermetallic alloys,particu-larly NiAl,Ni_(3)Al,and TiAl,whose engineering applications are substantial.It provides an overview of typical defect morphologies,formation mechanisms,and strategies to prevent cracks and pores.Additionally,it presents an analysis of the microstructural characteristics of as-built and post-treated samples compared with those of samples prepared conventionally.Furthermore,the mechanical properties of the above-mentioned alloys at both room and high temperatures are reviewed,thus highlighting the effects of post-treatment processes.This review concludes with summary tables detailing the mechanical properties,which serve as useful references for researchers.
基金Based on observations collected at the European Southern Observatory under ESO program(s)113.2661.001.
文摘The inner Milky Way disk globular cluster NGC 6362 appears to exhibit tidal tails composed of stars that have proper motions and positions in the color–magnitude diagram similar to those of cluster stars. Because recent results seem also to show that these stars are distributed across the regions least affected by interstellar absorption and reproduce the observed composite star field density map, we carried out a detailed spectroscopic analysis of a number of chemical element abundances of tidal tail star candidates in order to investigate the relationship between them and NGC 6362. From European Southern Observatory's VLT@FLAMES spectra we found that the red giant branch stars selected as the cluster's tidal tail stars neither have overall metallicities nor abundances of Mg, Ca, Sc, Ti, Cr, Ni and Ba similar to the cluster's ones. Moreover, they are mainly alike to stars that belong to the Milky Way thick disk, some of them could be part of the thin disk and a minor percentage could belong to the Milky Way halo star population. On the other hand, since the resulting radial velocities do not exhibit a distribution function similar to that of the cluster's stars, we concluded that looking for kinematic properties similar to those of the cluster would not seem to be as suitable of an approach for selecting the cluster's tidal tail stars as previously thought.
文摘It was in the 1980s that research on somatostatin(SST)in Alzheimer’s disease(AD)truly gained traction,demonstrating consistent colocalization with amyloid-β(Aβ),along with massive SST/SST cell losses(Almeida,2024).Although the field already had some grasp over the neuroendocrine and hypothalamic functions of the peptide,very little was known about the GABAergic interneurons(SST-INs)that synthesize it in cortical/hippocampal regions.Quite excitingly,over 40 years later,research has grown effervescent.
基金supported by Decit/SCTIE-Ministério da Saúde,Conselho Nacional de Desenvolvimento Científico e Tecnológico(CNPq),Fundação de AmparoàPesquisa do Estado de Alagoas(FAPEAL)and Secretaria de Estado da Saúde de Alagoas(SESAU-AL)[PPSUS 60030000841/2016].
文摘Objective:To investigate mutations in the Chikungunya(CHIKV)envelope genome region and evaluate their potential impact on B lymphocyte epitopes via in silico analysis.Methods:E1,E2 and 6K protein genes were sequenced from viral RNA isolated from 13 CHIKV-positive serum samples from Alagoas State,Brazil,during the 2016 outbreak.Phylogenetic analysis,experimental epitope identification in the immune epitope database(IEDB)and in silico approaches were employed to predict the potential impact of the detected mutations.Results:The sequences were clustered via phylogenetic analysis.The CHIKV isolates belong to the ECSA genotype,with 13 detected amino acid mutations.Five mutations are located on the surface of the viral particle in regions critical for cellular receptor interaction.Nine mutations are known experimentally validated epitopes for B and T cells.In B-cell epitope predictions,mutations affect sequences within three conformational epitopes in E2 and one in E1,as well as linear epitopes.Notably,the E2-G60D mutation found in the Alagoas strain has been previously reported to influence the vector competence of Aedes aegypti,the primary vector in Brazil.Conclusions:Genomic surveillance and an in-depth understanding of viral mutations are crucial for adapting public health strategies and improving the outbreak response.These findings could have significant public health implications,such as the development of more effective vaccines,diagnostic tests,and antiviral therapies.
基金supported by the Technical Project of Guangdong Province, China (Nos. 2020B090923002, 2021A1515011756)GDAS’ Project of Science and Technology Development, China (No. 2021GDASYL20210302006)+3 种基金Sciences Platform Environment and Capacity Building Projects of GDAS, China (No. 2021GDASYL-20210102005)Key R&D Program of Guangdong Province, China (No. 2020B090923002)Guangdong Special Support Program, China (No. 2019BT02C629)Guangdong Basic and Applied Basic Research Fund, China (Nos. 2020A1515111031, 2021A1515010939)。
基金Anglo American and Knowledge Center for Biodiversity for financial supportthe research funding agencies CNPq(Conselho Nacional de Desenvolvimento Científico e Tecnológico)+2 种基金scholarship from CNPq(151341/2023-0,150001/2023-1)FAPEMIG(Fundação de AmparoàPesquisa do Estado de Minas Gerais)Peld-CRSC 17(Long Term Ecology Program-campo rupestre of Serra do Cipó)。
文摘Land use change and occupation have led to modifications in the environment causing loss of biodiversity and ecosystem services throughout the planet.Some environments with high economic relevance,such as the ferruginous campo rupestre(rupestrian grassland known as Canga in Brazil),are even more susceptible to severe impacts due to their extreme habitat conditions and low resilience.The determination of reference ecosystems based on the intrinsic characteristics of the ecosystem is essential for conservation as well as to the implementation of ecological restoration.We proposed the reference ecosystem of the three main types of habitats of the ferruginous campo rupestre based on their floristic composition.We described the floristic composition of each habitat and evaluated the physicochemical properties of the soils and the relationship between plants and soils.All three habitats showed high diversity of plant species and many endemic species,such as Chamaecrista choriophylla,Cuphea pseudovaccinium,Lychnophora pinaster,and Vellozia subalata.The distribution of vegetation was strongly related with the edaphic characteristics,with a set of species more adapted to high concentration of base saturation,fine sand,organic carbon,and iron,while another set of species succeeded in more acidic soils with higher S and silt concentration.We provide support for the contention that the ferruginous campo rupestre is a mosaic of different habitats shaped by intrinsic local conditions.Failure to recognize the floristic composition of each particular habitat can lead to inappropriate restoration,increased habitat homogenization and increased loss of biodiversity and ecosystem services.This study also advances the knowledge base for building the reference ecosystem for the different types of ferruginous campo rupestre habitats,as well as a key database for highlighting those species contribute most to community assembly in this diverse and threatened tropical mountain ecosystem.
文摘针对智能交通领域多车协同驾驶中存在的通信信息乱序、丢包问题,研究网联式自主驾驶车辆协同控制技术,建立基于零阶保持(Zero Order Hold,ZOH)信息处理机制的自主驾驶车队控制模型,通过非线性系统状态估计算法进行延迟补偿,使得车队控制模型在复杂汽车行驶环境下保持有效。通过构建由多辆实车组成的网联式自主驾驶车队,在封闭道路环境下进行协同驾驶编队测试,结合网络传输及传感器数据进行模型仿真,验证了模型在实车编队环境下的稳定性、有效性和实用性。
基金financially supported by the National Natural Science Foundation of China(No.51574196)the 111 Project(No.B08040)+1 种基金the support from programs of China Scholarship Council(No.201404490058)Marie-Curie(No.268696)
文摘This work focused on the deposition characteristics and wear behavior of Ni-coated graphite mixed with40 vol.% Al（Ni-Gr/Al） composite coatings sprayed on an Al alloy and a steel substrate by cold spraying（CS）. The morphology of the flattened Ni-Gr particles was examined by single-impact tests. Crosssectional microstructure and wear performance of the Ni-Gr/Al composite coatings were studied. Results showed that a larger number of Ni-Gr particles were finally bonded with the steel substrate, whereas many craters existed on the Al alloy substrate after the single-impact tests. The coating on the steel substrate had a high thickness, high graphite content and low coeficient of friction（COF） compared to those on the Al alloy substrate. In addition, the CS coatings presented a homogeneous distribution and uniform morphology of graphite, and a comparative COF to that of conventional thermal sprayed coatings. It was shown that CS could avoid the decomposition and transformation of graphite phase.
文摘This work concerns the structural evolution of Cu70Nb20Al10(at%) alloy processed by mechanical alloying using a planetary ball mill in air atmosphere for different times(4 to 200 h). The morphological, structural, microstructural, and thermal behaviors of the alloy were investigated by scanning electron microscopy, energy-dispersive spectroscopy, X-ray diffraction, and differential scanning calorimetry. X-ray diffraction patterns were examined using the Rietveld refinement technique with the help of the MAUD software. A disordered FCC-Cu(Nb,Al) solid solution was formed after 8 h of milling. The crystallite size, microstrain, and lattice parameter were determined by the Rietveld method. With increasing milling time, the crystallite size of the final product-ternary-phase FCC-Cu(Nb,Al)-is refined to the nanometer scale, reaching 12 nm after 200 h. This crystallographic structure combines good mechanical strength and good ductility. An increase in microstrain and partial oxidation were also observed with increasing milling time.
基金financially supported by the National Natural Science Foundation of China (No. 51872254)the National Key Research & Development Program of China (No. 2017YFE0115900)the Outstanding Youth Foundation of Jiangsu Province of China (No. BK20210027)。
文摘The excessive concentration of NO_(2) in the atmosphere has gained considerable attention due to its damage to the environment and human health. Gas sensor technology has important application prospects in detecting atmospheric NO_(2) concentration. Restricted by its wide bandgap, pristine ZnO needs additional energy to power the electronic transition as a gas sensing material.
基金funding from Conselho Nacional de Desenvolvimento Científico e Tecnológico(CNPq-Brazil)Coordenacao de Aperfeicoamento de Pessoal de Nível Superior(CAPES-Brazil)+1 种基金Fundacao de AmparoàPesquisa do Estado do Rio Grande do Sul(FAPERGS-Brazil)Fundo de IncentivoàPesquisa e Eventos do Hospital de Clínicas de Porto Alegre(FIPE/HCPA-Brazil)(to LSdeF)。
文摘Function of lactate:Lactate is a three-carbon molecule produced by glycolytic metabolism that is a metabolic waste product with no known use in clinical therapy.Conversely,it is a metabolite that the body should quickly guarantee the clearance.However,lactate is now recognized as a potential energy substrate,as well as an anti-inflammatory signaling molecule.These actions were first reported in adult animal models with a brain injury,including a traumatic brain injury and cerebral ischemia,and have also been observed in human patients(Magistretti and Allaman,2018).Recently,however,two studies by independent research groups described promising n euro p rotective results from the use of lactate in animal models with neonatal hypoxia-ischemia(Roumes et al.,2021;Tassinari et al.,2020).
文摘The. objectives.of this study are to convert at laboratory s.cale agric.ultural residues into activated carbons （AC） with specific properties, to characterize them and to test them in adsorption reactor for tetracycline removal, a common antibiotic. Two new ACs were produced by direct activation with steam from beet pulp （BP-H2O） and peanut hu_lls （PH-H2O） in environmental friendly conditions BP-H2O and PH-H2Opresentcarbon content rangedcarbons with different intrinsic properties.
基金financial support from China Scholarship Council for his Ph.D. projectThe TEM facility in Lille, France, is supported by the Conseil Regional du Nord-Pas de Calais and the European Regional Development Fund
文摘A fully dense carbon nanotubes (CNTs) reinforced AlSi matrix composite with the multiscale nacre-like architecture was designed and successfully realized by flake powder metallurgy followed by cold spraying (CS). The nanolaminated and ultrafine-grained structure initially created in the CNT/AlSi flaky powder was perfectly conserved, due to the typical ‘cold’ feature of CS. As discussed based on finite element analysis and single splat observation, self-alignment behavior of the flaky powders during impact also allowed the formation of the microlaminated structure. Hence, the scalable CS technique opens a new avenue for bioinspired material design and fabrication with complex shape.
